co URSE Medical Microbiology 3 COURSE CODE MMB310S

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1 @ セ M オセ M セセ M@ M セ M -- M M POLYTECHNIC OF NAMIBIA SCHOOL OF HEALTH AND APPLIED SCIENCES Department of Health Sciences セ BACHELOR OF BIOMEDICAL SCIENCES QU ALIFICATION: ALIFICATION 50BMES NQF LEVEL: 7 DE: セ - セ co URSE Medical Microbiology 3 COURSE CODE MMB310S TE: November 2014 SESSION セ RATION: 2 hours MARKS: セ MM - SECOND OPPORTUNITY EXAMINATION QUESTION PAPER EXAMINER: MODERATOR: Dr RT Mavenyengwa DrJ Ojulong THIS QUESTION PAPER CONSISTS OF _5_PAGES (INCLUDING THIS FRONT COVER) INSTRUCTIONS: 1. Answer all questions as specified under each section (A, 8, C, D and E). 2. Sections A, 8 and C must be answered on the question paper. Section D and E must be answered on separate scripts provided. 3. Please write neat and legibly. 4. Do not use the left side of the test paper. This is left for the marker. 5. No books, notes and any other additional aids are allowed. 6. Mark all answers clearly with their respective question numbers.

2 Section A Answer all questions in this section. Select and circle the correct answer out of a choice of 4 (A, B, C and D). There is only one correct answer. This section carries a total of 5 marks. Windhoek is the capital city of A. South Africa B. Botswana C. 1. The following is true concerning the Rinyoun Group II mycobacteria: A. They are usually pathogenic B. They are photochromogens C. They are slow growers D. They include Mycobacterium marinum 2. Microscopic Observation Drug Susceptibility Agar (MODS): A. utilizes mycobacteria's faster grow1h in solid than on liquid media B. detects presence of Mycobacterium tuberculosis and determines Drug Susceptibility Testing to rifampicin and isoniazid direct from a sample at the same time C. requires 5 to 21 hours as time to Mycobacterium tuberculosis and Multi-drug resistance detection D. does not depend on the morphological cording growth of Mycobacterium tuberculosis 3. The following is typical of fungal stages and forms: A. Somatic stage is the reproductive and basic form B. Sexual reproductive structures are called the anamorphic phase C. Asexual reproductive structures are called the teleomorphic phase D. The macroconidia and microconodia are asexual stages 4. Tinea unguium is a superfcial infection which affects the: A. feet B. main trunk of the body C. nails D. head 2

3 5. The dermatophytes have the following diagnostic characteristics: A. Malassezia furufur forms structures called spaghetti and meatballs B. Microsporum has macroconidia that are spindle shaped C. Trichophyton has macroconidia that are club-shaped D. Epidermophyton has macroconidia that are shaped in a cylindrical form [5] Section B Answer all questions in this section. Fill in the correct answer in the given spaces provided to complete the given statements. There are a Total of 5 marks in this section. Each response carries% a mark. In the bacterial growth curve, the first phase is the.... Lag... phase and the last is called the... Death... phase. 1. Cryptococcus can be grown on special media such as..... or 2. The two laboratory tests used to confirm the identity of Candida albicans are and Taenia solium is mainly associated with infection of... whereas Taenia saginata is associated with type of meat.. type of meat. 4. a) Koplik spots are typical of infection with the virus b) Mumps virus have a predilection for the tissues of the Safe storage of food is normally at safe temperatures below... C or above.... oc [5] Section C Answer all questions in this section Answer True (T) or False (F) for each statement by putting a circle around the correct answer. There are a Total of 25 marks in this section. Concerning bacteria (j) F they multiply by binary fission T Whey are eukaryotic rtv F their strengthening layer is the cell wall Y (!)they all cause disease ([)1 F they have no nuclear membrane 3

4 1. Parasites infect different sites in the human body: T I F Giardia Iamblia infects the bone marrow T I F Dientamoeba tragi/is infects the liver and spleen T I F Paragonimus westermani infects the lungs T I F Trichinella spiralis infects the muscles T I F Trichmonoas vagina/is infects the urogenital system 2. The following parasites can be recovered when sputum is used as a specimen of choice: T I F Echinococcus granulosus T I F Necator americanus T I F Ascaris Jumbricoides T I F Ancylostoma duodenale T I F Strongyloides stercolaris 3. The following insects transmit these infections in humans: T IF Biting midges (Culicoides sp.): Onchocerciasis T IF Blackflies (Simulium sp.): Loiasis T IF Deerflies (Chrysops sp.) : Filariasis T I F Sandfiies (Phlebotomus) : Leishmaniasis T IF Tsetse fly (Glossina spp.): African Trypanosomiasis 4. Rotaviruses mainly cause infections in children: T I F They possess a segmented double stranded DNA T I F They are surrounded by a double layered icosahedral capsid without an envelope T I F Only two serotypes are known to infects humans T I F The infection caused has inflammation and has bloody stools T I F Adults are not infected at all 5. The food poisoning bacteria include T I F Salmonella which results from improperly canned foods T I F Staphylococcus aureus which manifests as the emetic or diarrhoeal forms T I F Vibrio cholerae which manifests as rice water stools T I F Shigella which results in loose blood diarrhea T I F Clostridium botulinum which results from ingestion of contaminated fried rice [20] 4

5 Section D Answer all questions in this section. There are a Total of 20 marks in this section. 1. Briefly describe the pathology which leads to the symptomatology in Leprosy (4) 2. By using examples of each class describe the various classes of arthropods of medical importance (4) 3. Identify the different groups of patients that are susceptible to Influenza viruses and are regarded as high risk groups (4) 4. Briefly outline the three clinical forms in an individual with actinomycosis (4) 5. What are the key principles in the Hazard Analysis Critical Control Point (HACCP) system (4) [20] Section E Answer all questions in this section. There are a Total of 50 marks in this section. 1. Briefly describe the infection called Tinea nigra in terms of aetiology and clinical manifestation (1 0) 2. Identify and highlight the general properties of trematodes (1 0) 3. By use of diagrams describe the HIV replication cycle (1 0) 4. Summarize the various laboratory diagnostic methods that are available for viruses of medical importance (1 0) 5. By using a simple diagram, explain the various stages through which drinking water in urban areas is treated (1 0) TOTAL END... [50] 5

namibia UniVERSITY OF SCIEnCE AnD TECHnOLOGY

namibia UniVERSITY OF SCIEnCE AnD TECHnOLOGY FACUL TV OF HEALTH AND APPLIED SCIENCES DEPARTMENT OF HEALTH SCIENCES QUALIFICATION: BACHELOR OF BIOMEDICAL SCIENCES QUALIFICATION CODE: SOBMES LEVEL: 7 COURSE