Material Safety Data Sheet

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1 Material Safety Data Sheet NFPA HMIS Personal Protective Equipment 2 0 Health Hazard Fire Hazard 2 0 See Section 5. Section. Chemical Product and Company Identification Page Number: Common Name/ Trade Name Tetracaine Catalog Number(s). YY20, TE220 CAS# Manufacturer SPECTRUM CHEMICAL MFG. CORP S. SAN PEDRO STREET GARDENA, CA RTECS TSCA DG TSCA 8(b) inventory: No products were found. Commercial Name(s) Synonym 4-Butylaminobenzoicacid-2-(dimethylamino)ethylester; Amethocaine Anetain p-(butylamino)benzoic acid, 2-(dimethylamino)ethyl ester p-butylaminobenzoyl-2-dimethylaminoethanol Intercain Laudocaine Medicaine Medihaler-tetracaine Meethobalm Niphanoid Benzoic acid, 4-(butylamino)-, 2-(dimethylamino)ethyl ester Contralgin Dicain Dicaine Dikain Dimethylaminoethyl p-butyl-aminobenzoate 2-Dimethylaminoethyl p-butylaminobenzoate Fissucain Metraspray Mucaesthin Pantocaine Pontocaine Rexocaine Tetracaine Uromucaesthin CI# IN CASE OF EMERGENCY CHEMTREC (24hr) Chemical Name Chemical Family Chemical Formula Supplier Benzoic acid, p-(butylamino)-, 2-(dimethylamino)ethyl ester C5H24N2O2 SPECTRUM CHEMICAL MFG. CORP S. SAN PEDRO STREET GARDENA, CA CALL (30)

2 Tetracaine Page Number: 2 Section 2.Composition and Information on Ingredients Exposure Limits Name CAS # TWA (mg/m 3 ) STEL (mg/m 3 ) CEIL (mg/m 3 ) % by Weight ) Tetracaine Toxicological Data on Ingredients Tetracaine: ORAL (LD50): Acute: 300 mg/kg [Mouse]. Section 3. Hazards Identification Potential Acute Health Effects Potential Chronic Health Effects Hazardous in case of skin contact (irritant, sensitizer), of eye contact (irritant), of ingestion. Slightly hazardous in case of inhalation. Slightly hazardous in case of skin contact (sensitizer). CARCINOGENIC EFFECTS: MUTAGENIC EFFECTS: TERATOGENIC EFFECTS: DEVELOPMENTAL TOXICITY: Section 4. First Aid Measures Eye Contact Skin Contact Serious Skin Contact Inhalation Serious Inhalation Ingestion Serious Ingestion Check for and remove any contact lenses. In case of contact, immediately flush eyes with plenty of water for at least 5 minutes. Get medical attention. In case of contact, immediately flush skin with plenty of water for at least 5 minutes while removing contaminated clothing and shoes. Cover the irritated skin with an emollient. Wash clothing before reuse. Thoroughly clean shoes before reuse. Get medical attention. Wash with a disinfectant soap and cover the contaminated skin with an anti-bacterial cream. Seek immediate medical attention. If inhaled, remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical attention. Evacuate the victim to a safe area as soon as possible. Loosen tight clothing such as a collar, tie, belt or waistband. If breathing is difficult, administer oxygen. If the victim is not breathing, perform mouth-to-mouth resuscitation. Seek medical attention. Do NOT induce vomiting unless directed to do so by medical personnel. Never give anything by mouth to an unconscious person. If large quantities of this material are swallowed, call a physician immediately. Loosen tight clothing such as a collar, tie, belt or waistband. Section 5. Fire and Explosion Data Flammability of the Product Auto-Ignition Temperature Flash Points Flammable Limits Products of Combustion Fire Hazards in Presence of Various Substances May be combustible at high temperature. These products are carbon oxides (CO, CO2), nitrogen oxides (NO, NO2...). Slightly flammable to flammable in presence of open flames and sparks, of heat. Explosion Hazards in Presence of Various Substances Risks of explosion of the product in presence of mechanical impact: Risks of explosion of the product in presence of static discharge: Fire Fighting Media and Instructions Fire Hazards SMALL FIRE: Use DRY chemical powder. LARGE FIRE: Use water spray, fog or foam. Do not use water jet.

3 Tetracaine Page Number: 3 Explosion Hazards Section 6. Accidental Release Measures Small Spill Large Spill Use appropriate tools to put the spilled solid in a convenient waste disposal container. Use a shovel to put the material into a convenient waste disposal container. Section 7. Handling and Storage Precautions Storage Keep away from heat. Keep away from sources of ignition. Ground all equipment containing material. Do not ingest. Do not breathe dust. Wear suitable protective clothing. If ingested, seek medical advice immediately and show the container or the label. Avoid contact with skin and eyes. Keep away from incompatibles such as oxidizing agents. Keep container tightly closed. Keep container in a cool, well-ventilated area. Sensitive to light. Store in light-resistant containers. Section 8. Exposure Controls/Personal Protection Engineering Controls Personal Protection Personal Protection in Case of a Large Spill Exposure Limits Use process enclosures, local exhaust ventilation, or other engineering controls to keep airborne levels below recommended exposure limits. If user operations generate dust, fume or mist, use ventilation to keep exposure to airborne contaminants below the exposure limit. Splash goggles. Lab coat. Dust respirator. Be sure to use an approved/certified respirator or equivalent. Gloves. Splash goggles. Full suit. Dust respirator. Boots. Gloves. A self contained breathing apparatus should be used to avoid inhalation of the product. Suggested protective clothing might not be sufficient; consult a specialist BEFORE handling this product. Section 9. Physical and Chemical Properties Physical state and appearance Solid. Odor Odorless. Molecular Weight ph (% soln/water) g/mole Taste Color White. Boiling Point Melting Point 4-46 C ( F) Critical Temperature Specific Gravity Vapor Pressure Not applicable. Vapor Density Volatility Odor Threshold Water/Oil Dist. Coeff. Ionicity (in Water) Dispersion Properties Solubility

4 Tetracaine Page Number: 4 Section 0. Stability and Data Stability Instability Temperature Conditions of Instability Incompatibility with various substances Corrosivity The product is stable. Excess heat, dust generation, light, incompatible materials Reactive with oxidizing agents. Non-corrosive in presence of glass. Corrosivity Polymerization Sensitive to light. Will not occur. Section. Toxicological Information Routes of Entry Toxicity to Animals Chronic Effects on Humans Other Toxic Effects on Humans Toxicity to Animals Chronic Effects on Humans other Toxic Effects on Humans Inhalation. Ingestion. Acute oral toxicity (LD50): 300 mg/kg [Mouse]. Hazardous in case of skin contact (irritant, sensitizer), of eye contact (irritant), of ingestion. Slightly hazardous in case of inhalation. May affect genetic material (mutagenic) Acute Potential Health Effects: Skin: May cause skin irritation. May cause sensations of heat, cold or numbness. Eyes: Causes eye irritation. May cause sensations of heat, cold or numbness. Inhalation: May cause respiratory tract irritation. Ingestion: Harmful if swallowed. May cause gastrointestinal tract irritation with nausea and vomiting. May affect respiration (respiratory depression) and behavior/central nervous system (central nervous system depression, muscle weakness, euphoria, confusion, dizziness, light-headedness, twitching, tremors, drowsines, convulsions, unconciousness), ears (tinnitus), vision (blurred vision, double vision), cardiovascular system (hypotension, myocardial depression, bradycardia, and possibly cardiac arrest, or cardiovascular collapse). May cause sensations of heat, cold or numbness. Chronic Potential Health Effects: Skin: It may be a sensitizer and cause dermatitis, an allergic reaction. Symptoms may include itiching, hives, edema and swelling.. Section 2. Ecological Information Ecotoxicity BOD5 and COD Products of Biodegradation Toxicity of the Products of Biodegradation the Products of Biodegradation Possibly hazardous short term degradation products are not likely. However, long term degradation products may arise. The products of degradation are less toxic than the product itself.

5 Tetracaine Page Number: 5 Section 3. Disposal Considerations Waste Disposal Waste must be disposed of in accordance with federal, state and local environmental control regulations. Section 4. Transport Information DOT Classification CLASS 6.: Poisonous material.r68- Identification UNNA: 28 : Toxic Solid, inorganic, n.o.s. (Tetracaine) PG: III Special Provisions for Transport DOT Section 5. Other Regulatory Information and Pictograms Federal and State Regulations California Proposition 65 Warnings Other Regulations TSCA 8(b) inventory: No products were found. California prop. 65: This product contains the following ingredients for which the State of California has found to cause cancer which would require a warning under the statute: No products were found. California prop. 65: This product contains the following ingredients for which the State of California has found to cause birth defects which would require a warning under the statute: No products were found. OSHA: Hazardous by definition of Hazard Communication Standard (29 CFR ). EINECS: This product is on the European Inventory of Existing Commercial Chemical Substances (EINECS No ). Canada: Not listed on Canadian Domestic Substance List (DSL) or Canadian Non-domestic Substance List (NDSL) China: Not isted on National Inventory. Japan: Not listed on National Inventory (ENCS). Korea: Not listed on National Inventory (KECI). Philippines: Not listed on National Inventory (PICCS). Australia: Listed on AICS. Other Classifications WHMIS (Canada) CLASS D-B: Material causing immediate and serious toxic effects (TOXIC). CLASS D-2B: Material causing other toxic effects (TOXIC). DSCL (EEC) R22- Harmful if swallowed. R36/38- Irritating to eyes and skin. R43- May cause sensitization by skin contact. R68- Possible risk of irreversible effects. S26- In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39- Wear suitable protective clothing, gloves and eye/face protection. S45- In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible). HMIS (U.S.A.) Health Hazard Fire Hazard Personal Protection 2 0 E National Fire Protection Association (U.S.A.) Health 2 0 Flammability Specific hazard WHMIS (Canada)

6 Tetracaine Page Number: 6 DSCL (Europe) TDG (Canada) ADR (Europe) Protective Equipment Gloves. Lab coat. Dust respirator. Be sure to use an approved/certified respirator or equivalent. Wear appropriate respirator when ventilation is inadequate. Splash goggles. Section 6. Other Information MSDS Code References Other Special Considerations T3200 Validated by Sonia Owen on 8/3/202. Verified by Sonia Owen. Printed 8/3/202. CALL (30) Notice to Reader All chemicals may pose unknown hazards and should be used with caution. This Material Safety Data Sheet (MSDS) applies only to the material as packaged. If this product is combined with other materials, deteriorates, or becomes contaminated, it may pose hazards not mentioned in this MSDS. It shall be the user's responsibility to develop proper methods of handling and personal protection based on the actual conditions of use. While this MSDS is based on technical data judged to be reliable, Spectrum Quality Products, Inc. assumes no responsibility for the completeness or accuracy of the information contained herein.

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