MAESTRO: Methods and Advanced Equipment for Simulation and Treatment in Radiation Oncology
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1 What is MAESTRO? Sixth Framework Program FP6 ( ) European Commission Integrated Project Duration: 5 years MAESTRO: Methods and Advanced Equipment for Simulation and Treatment in Radiation Oncology
2 Consortium Agreement Research Commissariat à l Energie Atomique (CEA) - Paris Istituto Nazionale di Fisica Nucleare (INFN) LNS + Turin NPL Management Ltd (NPL) - United Kingdom Instytut Fizyki Jadrowej (IFJ) - Krakow IN2P3 -Paris Istituto Superiore di Sanità (ISS) - Rome Delft University of Technology (TUD.IRI) - Germany Coventry University (Coventry) - United Kingdom Universitat de Barcelona (UCB)- Barcelona University of East Anglia (UEA) - United Kingdom Universidad de Castilla (UCLM) - Spain
3 Consortium Agreement Industrials Ion Beam Applications (IBA) Belgium DOSISOFT - France ELDIM - France Nuclear Research and consultancy Group (NRG) Germany Scanditronix Wellhöfer (SCX) Sweden
4 Consortium Agreement Clinics Institut Gustave Roussy (IGR) France Centre François Baclesse (CFB) France REM Radioterapia (REM) - Catania University Hospitals Coventry and Warwickshire (UHCW) United Kingdom Universitat Duisburg-Essen (UDE) - Germany Centrum Oncologii Oddzial w Krakowie (COOK) Krakow Università di Firenze, Dipartimento di Fisiopatologia clinica (DFC) - Florence
5 Outline Implementation Plan WP1 WP2 WP3 WP4 WP5 WP6 Adaptive Radiotherapy Treatment Pencil beam delivery system for protontherapy Radiotherapy Software Development Sensors for dose evaluation Clinical requirements Training and demonstration workshops Management
6 Work Package1 1. Patient Positioning (Coventry) 2. Development of a phantom with monitored mobile organs (UEA,UCLM) 3. Development of a system for monitoring corrections of organ motion (DOSisoft, INRIA) 4. Pencil Beam delivery system for protontherapy (IBA) Adaptive Radiotherapy Treatment
7 WP1.4 Pencil Beam Scanning for Protontherapy
8 Work Package2 1. Treatment simulation and patient representation (DOSisoft, INRIA) 2. Calculation for 3D dose distribution (DOSisoft, UCB)
9 WP2.1 Treatment Simulation and patient representation Products list: IMAGO for physician station SIMAGO for virtual simulation station COMPAR for comparison between planned and realised treatment AMIRTOS for IMRT EXAcor for dosimetric verification
10 WP2.2 Calculation for 3D dose distribution Software features: Use of Montecarlo codes Characterization of photon and electron beams delivered by linear accelerator Platform for fast calculation, for electrons beam Generation of input data (kernel, depth dose, profile of photon beamlets) for the TPS 3D dose distribution calculation for conformational radiotherapy and IMRT
11 Work Package3 1. Diamond dosimetry IC & TL (CEA) 2. OSL (CEA) 3. 2D Silicon detector (DFC) 4. Gas Electron Multiplier (TUD.IRI) 5. Pixel Ionization Chamber (IBA, Wellhofer-SCX) 6. 2D TLD (IFJ) 7. Gel readout (ISS) 8. 3D plastic dosimetry (ELDIM)
12 WP3.1 Diamond dosimetry
13 WP3.2 OSL (Optical Stimulated Luminescence)
14 WP3.3 2D Silicon detector
15 WP3.4 GEM applications in Protontherapy
16 WP3.5 Pixel Ionization Chamber
17 WP3.5 Pixel Ionization Chamber
18 WP3.6 2D Termoluminescence Dosimetry
19 WP3.7 Gel readout
20 WP3.8 3D Plastic Dosimetry
21 WP4 Clinical requirements 1. User s requirement for integration 2. Quality Assurance procedures and protocols 3. Pre-clinical and clinical validation processes 4. Risk assessment issues
22 WP5 Training and demonstration workshops 1. (NPL,TUD,DFC,UCB,CEA,INFN,INRIA,Cov,IGR) Report and training plan Decision on number and topic 2. (COOK,CFB,DFC) Report and demonstration plan Decision on number and topic
23 Maestro timetable Official start: May Contract being signed (< end july 04?) Duration: Phase 1: 18 months Phase 2: 60 months
24 INFN and MAESTRO Radiotherapy with protons: Clinical requirements Dosimetry (protocols, diamonds) Beam monitoring Monte Carlo Radiotherapy with photons: 1D dosimetry (diamonds) 2D dosimetry (pixel chamber) Coordination of the Executive Committee
25
26 WP1.4 Scanning Vs Scattering Tecnical Advantages
27 WP1.4 PBS Advantages
28 WP3.1 Why Diamond for radiotherapy dosimetry?
29 WP3.8 3D Plastic Dosimetry Active Plane Phantom Signal Processing
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