Tissue Core Tissue Microarray Inventory List

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1 size/mm Array description Tissue type # of cases AQUA 1 Pancreas AQUA 1 Pancreas 10 / Pancreas IDC, Panin, IPMN, normal & cysts various types Pancreas Dr. Malafa / Dr. Centeno Exclusive B ALL TMA B ALL 1 / ALL in clot & BM biopsy B.M Dr. Ling Zhang General purpose B Map-3 Her 2-8 / IDC, cell line (4 types) and Ctr.tissues (5) Breast Dr. Teresita Antonia PI Driven B Map-3 Her / IDC, cell line (4 types) and Ctr.tissues (5) Breast Dr. Teresita Antonia PI Driven B Map-3 TN-1 7 / IDC, cell line (4 types) and Ctr.tissues (5) Breast Dr. Teresita Antonia PI Driven B Map-3 TN-2 7 / IDC, cell line (4 types) and Ctr.tissues (5) Breast Dr. Teresita Antonia PI Driven B Map-3 TN-3 8 / IDC, cell line (4 types) and Ctr.tissues (5) Breast Dr. Teresita Antonia PI Driven B Map-3 PRBBBR Her 2-11 / IDC, cell line (4 types) and Ctr.tissues (5) Breast Dr. Teresita Antonia PI Driven B Map-3 PRBBBR Her / IDC, cell line (4 types) and Ctr.tissues (5) Breast Dr. Teresita Antonia PI Driven B Map-3 PRBBBR TN 11 / IDC, cell line (4 types) and Ctr.tissues (5) Breast Dr. Teresita Antonia PI Driven BE-P BE-P 10 / Normal, B.E., HGD, LGD, ICA, Mets. & controls & Stomach Dr. Coppola General Purpose Breast 3 2 / Micropapillary ca.& IDC Breast Dr. Acs General Purpose Breast / Normal, hyperplasia, carcinoma & cell lines Breast Dr.Yeatman / Dr.Coppola General Purpose Breast 2 b 4 / Normal, DCIS, IDC, L.N. macromet. & cell lines Breast Dr. Wu Jerry General Purpose Breast Ca. 4 4 / Normal,DCIS, IDC,L.N.macromet.& cell lines Breast Tissue General Purpose Breast 5 9 / TN BC,ER PR+ BC,N.breast,cell lines & controls Breast Dr. Lancaster / Dr. Marchion PI driven Cervix 1 6 / Cervix 2 5 / Cervix 3 8 / Cervix 4 2 / line Cervix Dr. Siegel / Dr. Hakam PI Driven line Cervix Dr. Siegel / Dr. Hakam PI Driven line Cervix Dr. Siegel / Dr. Hakam PI Driven line Cervix Dr. Siegel / Dr. Hakam PI Driven cmet Development cmet Development 4 / Lung adenoca. ca. + different controls Lung Dr. Haura / Matt Smith PI Driven

2 size/mm Array description Tissue type # of cases Colon 2 A 9 / Normal, adenoma, adenoca.,cell lines and controls Colon different 258 Dr. Shibata Exclusive Colon 2 B 9 / Normal, adenoma, adenoca.,cell lines and controls Colon different 258 Dr. Shibata Exclusive Colon 2 C 10 / Normal, adenoma, adenoca.,cell lines and controls Colon different 258 Dr. Shibata Exclusive Colon 2 D 10 / Normal, adenoma, adenoca.,cell lines and controls Colon different 258 Dr. Shibata Exclusive Colon Control 1 Colon Control 1 1 / Colon ca. and N. Colon Colon Dr. Magliocco PI Driven CRC TMA 1 12 / Cell lines Cell Lines Dr. Haura PI Driven Esophago gastric adenoca. EGA ca. 11 / Gastric, esophageal & GE junction adenoca., low stage & high stage + Ctr. IDC breast & Stomach Dr. Coppola PI Driven Extrahepatic Biliary duct TMA Extrahepatic BDT 5/21/ Extrahepatic biliary duct tumors+normal mucosa+controls (IDC breast her 2 +) Bile Duct Dr.Coppola PI Driven Gastro-esophageal tumor 1,2,3 3 / Adenoca. of the esophagus & stomach & Stomach Merck-Moffitt project General Purpose GIST 1 3 / GIST Many Dr. Pledger / Dr. Coppola General Purpose Glioma 1 9 / Glioma (different grades) and controls Brain Dr. Egan / Dr. Shan Exclusive Glioma 2 10 / Glioma (different grades) and controls Brain Dr. Egan / Dr. Shan Exclusive Glioma 3 12 / Glioma (different grades) and controls Brain Dr. Egan / Dr. Shan Exclusive Glioma 4 2 / Glioma (different grades) and controls Brain Dr. Egan / Dr. Shan Exclusive GVHD 1 6 / GI biopsies (different areas) mostly No GVHD GI Dr.Coppola / Dr. Sagatys General Purpose GVHD 2 7 / GI biopsies (different areas) mostly No GVHD GI Dr.Coppola / Dr. Sagatys General Purpose GVHD 3 11 / GI, skin & liver biopsies Many Dr. Pidala / Dr. Sagatys General Purpose GVHD 4 2 / GI & skin biopsies Many Dr. Pidala / Dr. Sagatys General Purpose GVHD 5 1 / GI & skin biopsies Many Dr. Pidala / Dr. Sagatys PI Driven HCC 1,2,3 5 / Hepatocellular ca. Liver Merck-Moffitt project General Purpose Lung 2 3 / Lung ca. / primary & mets. adenoca.and controls Many Dr. Haura / Dr. Khalil Exclusive

3 size/mm Array description Tissue type # of cases Lung 1 3 / Lung ca. / primary & mets.adenoca. and controls Many Dr. Haura / Dr. Khalil Exclusive Lung 3 6 / Lung ca. / primary & mets. adenoca. and controls Many Dr. Haura / Dr.Khalil Exclusive Lung 4 6 / Lung ca.(adenoca.,sq.cc,nscc,), mets., normal and controls Many Dr. Haura / Dr. Magliocco Exclusive Lung 5 (KRAS) 1 / Lung ca., normal lung tissue, controls and cell line Lung Dr. Haura Exclusive Lung 6 (ALK) 2 / Lung ca., controls and cell line Lung Dr. Haura Exclusive Lung 6-2 ALK Lung / Lung ca., cell line and controls Lung Dr. Haura PI driven Lung 7 4 / Lung ca. - primary & mets, different controls Lung & Many Dr. Robinson PI Driven Lung Control 1 Lung Control 1 1 / Lung ca. Lung Dr. Magliocco PI Driven Lung Small cell ca. Lung Small cell ca. 4 / Lung small cell ca., controls & cell line Lung Dr. Scott Antonia PI driven Lymphoma 1 3 / Hodgkin's lymphoma, Diffuse large B cell lymphoma & controls L.N Dr. Haipeng Shao General Purpose Melanoma 1 10 / Melanoma 2 1 / Normal, benign nevi, dysplastic nevi, Primary cutan.melanoma, M1,2,3, regional L.N. melanoma & primary mucosal melanoma Skin Dr. Sondak / Dr. Messina General Purpose Primary cutan. melanoma, subcutaneous melanoma, L.N.melanoma mets. & distant mets. Melanoma Skin Dr. Sondak / Dr. Messina Exclusive Melanoma stage 3&4 3 2 / Melanoma stage 3 &4 and controls Many Dr. Gibney / Dr. Messina PI driven Melanoma stage 3&4 4 2 / Melanoma stage 3 &4 and controls Many Dr. Gibney / Dr. Messina General purpose Melanoma 5 10 / Desmoplastic Melanoma Many Dr. Messina PI Driven Merkel cell Ca. Merkel cell Ca. 7 / Diff. tissues Primary lesion, L.N. involv. & recurrent/mets. cases Many Dr.Messina PI Driven Met Cells Met Cells TMA 3 / cell lines + controls Cell Lines Dr. Haura / Matt Smith PI Driven Mini Bladder 1 MRE11 Mini Bladder 1 MRE11 7 / Bladder ca., normal urothelial tissue & cell line Bladder Dr. Magliocco PI Driven Mini Myeloma 2 2 / Multiple myeloma and controls B.M Dr. Hazlehurst / Dr. Zhang General Purpose Mini Myeloma 10 / Multiple myeloma and controls B.M Dr. Hazlehurst / Dr. Zhang General Purpose Mini P BAD ov.ca 1 5 / / ovarian ca., normal ovary, normal fallopian tube, cell line and controls (normal kidney& breast ca.) Ovary & F.T Dr. Lancaster / Dr. Magliocco PI Driven

4 size/mm Array description Tissue type # of cases MM / MM cases, normal BM & cell line B.M Dr. Hazlehurst / Dr. Zhang PI Driven Mouse EM Mouse EM TMA 3 / Mouse uterus endometriosis, ovary, different controls Uterus & Ovary Meera / USF PI Driven Next Gen OVCA 1 2 / 2015 ovary cancer, normal ovary, N.FT, different controls & cell lines Ovary Dr. Wey PI Driven Next Gen OVCA 2 2 / 2015 ovary cancer, normal ovary, N.FT, different controls & cell lines Ovary Dr. Wey PI Driven Next Gen OVCA 3 2 / 2015 ovary cancer, normal ovary, N.FT, different controls & cell lines Ovary Dr. Wey PI Driven Next Gen OVCA 4 2 / 2015 ovary cancer, normal ovary, N.FT, different controls & cell lines Ovary Dr. Wey PI Driven Next Gen OVCA 5 2 / 2015 ovary cancer, normal ovary, N.FT, different controls & cell lines Ovary Dr. Wey PI Driven Osteosarcoma 3 3 / Osteosarcoma in different sites, mets. and controls Many Dr. Bui Exclusive Osteosarcoma 4 3 / Osteosarcoma in different sites, mets. and controls Many Dr. Bui Exclusive Ovarian tumor 1 8 / different types of ovarian tumor Ovary Dr. Tuya Pal / Dr. Coppola General Purpose P BAD ov.ca / ovarian ca., normal ovary, normal fallopian tube, cell line and controls (normal kidney& breast ca.) Ovary & F.T Dr. Lancaster / Dr. Magliocco General Purpose Pancreas 1 1 / Normal, IDC & cell lines Pancreas Dr. Malafa / Dr. Centeno General Purpose Pancreas 2 3 / Normal, IDC & cell lines Pancreas Dr. Malafa / Dr. Centeno General Purpose Pancreas 3 9 / Normal, IDC & cell lines Pancreas Dr. Malafa / Dr. Centeno General Purpose Pancreas 4 9 / Neuroendocrine ca.(well-mod.diff.) Pancreas Dr. Nasir General Purpose Pancreas 5 9 / Neuroendocrine ca. Pancreas Dr. Nasir General Purpose Pancreas 6 A 8/6/ Normal,IDC, cell lines & Ctr. Tissue tissue Dr. Malafa PI driven Pancreas 6 B 8/13/ Normal,IDC, cell lines & Ctr. Tissue tissue Dr. Malafa PI driven Pancreas 6 C 8/26/ Normal,IDC, cell lines & Ctr. Tissue tissue Dr. Malafa PI driven Control 1 Control 1 1 / ca., N. Pancreas & N. Duodenum Pancreas Dr. Magliocco PI Driven tumor 11,12,13 4 / Adenoca. of the pancreas Pancreas Merck-Moffitt project General Purpose Penile ca. TMA Penile ca. 6/16/ Penile SCC+ controls Penis Dr. Dhillon PI driven PR BB Colon / Colon ca., HGD, Adenoma, N. colon, cell line & controls Colon Dr. Munoz-Antonia PI driven

5 size/mm Array description Tissue type # of cases PR BB Colon / Colon ca., HGD, Adenoma, N. colon, cell line & controls Colon Dr. Munoz-Antonia PI driven PR BB Colon / Colon ca., HGD, Adenoma, N. colon, cell line & controls Colon Dr. Munoz-Antonia PI driven Prostate 3 1 / BPH, PIN, G6, G7, G8-9-10, mets. & cell lines Prostate Dr. Mahajan General Purpose

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