16:00 17:15 hrs - Session 1 - Rare diseases and new approaches. Chair: Alexander Claviez (Kiel), Krzysztof Kalwak (Wroclaw)

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1 9. June 2016 Friday afternoon (15:00-19:00 hrs) 15:45-16:00 hrs - Welcome address: Alicja Chybicka (Wrocław) Krzysztof Kalwak (Wroclaw) Meinolf Suttorp (Dresden) Petr Sedlacek (Prague) 16:00 17:15 hrs - Session 1 - Rare diseases and new approaches Chair: Alexander Claviez (Kiel), Krzysztof Kalwak (Wroclaw) - Carl Friedrich Classen (D) - confirmed Glioblastoma how to cure the (almost) incurable disease? New hints from the research. - Meinolf Suttorp (D)- confirmed Can we stop treatment in CML patients? - Alexander Claviez (D) - confirmed Brentuximab vedotin in the treatment of CD30+ HL and NHL.

2 17:15-17:45 hrs - Coffee Break 17:45 19:15 hrs - Session 2 - Acute lymphoblastic leukemia - Wojciech Młynarski- confirmed Chair: Bernd Gruhn (Jena), Meinolf Suttorp (Dresden) How to optimise the use of L-asparaginase? from bench to clinic and back - Marketa Zaliova- confirmed IKAROS and ERG mutations in ALL. Do they mean much? - Agata Pastorczak- confirmed Distinct clinical and biological features of acute lymphoblastic leukemia in patients with chromosomal instability syndromes. - Krzysztof Kalwak - confirmed Do we need to think about immunoglobulin substitution in children with leukemia and lymphoma and post HSCT? New drugs, new protocols brand new problems. from 19:30 hrs Networking Dinner

3 08:30 10:00 hrs - Session 3 - The broad field of pediatric stem cell transplantation - Petr Sedlacek(CZ)- confirmed Chair: Karl W. Sykora (Hannover), Jacek Wachowiak (Poznan) VOD should we use defibrotide prophylaxis or just save the precious drug for treatment only? - Peter Svec (SK)- confirmed Definition and therapy of TMA after HSCT - Krzysztof Kalwak(PL)- confirmed Haploidentical transplants in children: PTCY or T cell depleted - Catharina Schuetz (D)- confirmed Late effects of HSCT in SCID patients. Should we condition or not? 10:00-10:30 hrs - Coffee Break 10:30 12:00 hrs - Session 4 HSCT in non-malignant disorders - Jacek Wachowiak- confirmed Chair: Ursula Creutzig (Hannover), Petr Sedlacek (Prague) SAA/PNH whom and when to transplant? - Joern-Sven Kuehl- confirmed

4 Long follow up of patients with X-ALD posttransplant - Karl Walter Sykora- confirmed Current guidelines on SCT/ERT in metabolic disorders? 12:00-13:30 Lunch 18. June 2016 Saturday afternoon (13:30-18:00 hrs) 13:30 14:45 hrs - Session 5 - Acute myeloid leukemia - Ursula Creutzig - confirmed Chair: Ursula Creutzig (Munich), Dirk Reinhardt (Essen), CNS positive AML is there a problem? - Dirk Reinhardt - confirmed New drugs in the treatment of childhood AML - inquired - Ursula Creutzig- confirmed AML in Down Syndrome patients hrs. Session 6 Cord blood and Wharton s Jelly derived MSCs Chair: Petr Sedlacek (Prague), Krzysztof Kalwak (Wroclaw)

5 - Krzysztof Kalwak(PL) - confirmed CBT is there still a role for MSD or UD CBT in the era of haploidentical transplants? - Magdalena Chrościńska-Krawczyk(Lublin, PL)- confirmed Mesenchymal Stem Cells i.v. and i.t. in neurology Polish Experience 15:45-16:15 hrs - Coffee Break 16:15 18:00 hrs - Session 7: Pretty Kettle of Fish - Eine schöne Bescherung No to pięknie! - To je ale nadělení! Ez aztán szép kis meglepetés! - Čo sa to tu deje? Chair: Krzysztof Kalwak (Wroclaw), Meinolf Suttorp (Dresden) from 19:45 hrs - Outdoor dinner 19. June 2016 Sunday morning (09:00-12:30 hrs) 09:00 10:00 hrs - Session 8 Iron overload: Chair T.B.A. - Sabina Sufliarska-inquired

6 Iron overload in Slovakian SCT and hematooncological pts - Jowita Frączkiewicz- confirmed Which transplant patients are good candidates for iron chelation therapy? - Regine Grosse- inquired German guidelines on iron overload in pediatric hematooncological patients 10:00-11:00 hrs Session 9 - Infectious complications in pediatric hematooncology, Chair: T.B.A Topics: - Michał Matysiak confirmed, title T.B.A T.Ociepa (inquired) - Echinocandins are they all the same? N.Irga-Jaworska (inquired) - Antimold prophylaxis in pediatric patients a bless or curse? T.B.A. - New and old antifungal drugs how to deal with such a rich armamentarium? Coffee Break 11:30 12:30 hrs - Session 8: From bench and bedside Chair: Petr Sedlacek (Prague), Meinolf Suttorp (Dresden) Abstracts of young investigators selected for oral presentation

7 - Marek Ussowicz (PL) - confirmed Ataxia-Teleangiectasia is there a role for HSCT? Presentation of awards to best abstracts presenters and adjourn

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