LEUKEMIAS 2017 ACUTE & CHRONIC ENCORE AT WYNN LAS VEGAS LAS VEGAS, NEVADA OCTOBER 6 7, 2017

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1 Jointly provided by Mayo School of Continuous Professional Development and Mayo Continuing Nursing Education ACUTE & CHRONIC LEUKEMIAS 2017 REGISTER NOW! $75 DISCOUNT For Early Registration Expires 9/6/2017 Jose F. Leis, M.D., Ph.D. KEYNOTE PRESENTATION Chronic Lymphocytic Leukemia: Emerging Therapies And Highlights Of Current Practice ENCORE AT WYNN LAS VEGAS LAS VEGAS, NEVADA OCTOBER 6 7, 2017 CE.MAYO.EDU/LEUKEMIA2017

2 COURSE DESCRIPTION This is a two-day comprehensive symposium that will feature interactive case presentations with a panel of experts weighing in on pivotal treatment issues as well as taking questions from the audience. These sessions will highlight standard of care, new treatments, side effects of treatment, as well as any pertinent clinical issues of a specific diagnosis. The interactive case presentations topics will be: Chronic Myeloid Leukemia, Myeloproliferative Neoplasms, Acute Myeloid Leukemia, and Chronic Lymphoid Leukemia. The second day of the symposium will have didactic sessions to address updates in: Acute and Chronic Myeloid Leukemia, Myeloproliferative Neoplasms, Myelodysplastic Syndromes, Acute Myeloid Leukemia, Acute and Chronic Lymphoid Leukemia, Acute Lymphoblastic Leukemia, BMT Updates in 2017, Palliative Care, and Infectious Disease issues in this population. LEARNING OBJECTIVES Upon completion of this activity, participants should be able to: Demonstrate treatments for relapsed Acute Lymphoblastic Leukemia. Describe outcomes of patients with relapsed Acute Lymphoblastic Leukemia. Recognize when to use ibrutinib in Chronic Lymphoid Leukemia. Identify side effects of ibrutinib treatment. Describe what molecular markers to look for in Myeloproliferative Neoplasms. Recognize the importance of molecular markers in the treatment of Myeloproliferative Neoplasms. Identify which patients are eligible for stem cell transplant. Identify the use of different donor sources for stem cell transplant and the role of haploidentical transplant in Attendance at this Mayo Clinic course does not indicate nor guarantee competence or proficiency in the performance of any procedures which may be discussed or taught in this course. INTENDED AUDIENCE This course is designed for Physicians, Pharmacists, Nurses, Nurse Practitioners, Physician Assistants, Fellows, and Residents in the following specialties: Hematology/Oncology, Internal Medicine, Hospital Medicine, Hematopathology, and Medical Oncology.

3 CREDIT Mayo Clinic College of Medicine and Sciences is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians. Mayo Clinic College of Medicine and Sciences designates this live activity for a maximum of 11 AMA PRA Category 1 Credits. Physicians should claim only the credit commensurate with the extent of their participation in the activity. AAFP Application for CME credit has been filed with the American Academy of Family Physicians. Determination of credit is pending. AOA This program has been accredited by the American Osteopathic Association for 11 credits of AOA Category 2-A. ACPE Mayo Clinic College of Medicine and Science is accredited by the Accreditation Council for Pharmacy Education as a provider of continuing pharmacy education. Mayo Clinic College of Medicine and Science designates this educational activity for a maximum of 9.75 ACPE Knowledge-based contact hours. Participants should claim only the credit commensurate with the extent of their participation in the activity. Participants must complete the entire activity and are required to complete an online evaluation(s) to earn credit. ANCC This conference is offered in cooperation with Mayo Continuing Nursing Education. Mayo Continuing Nursing Education is accredited with distinction as a provider of continuing nursing education by the American Nurses Credentialing Center s Commission on Accreditation. Participants can earn up to 9.25 ANCC nursing contact hours commensurate with the extent of their participation in the activity. MEETING LOCATION AND ACCOMMODATIONS Encore at Wynn Las Vegas 3121 Las Vegas Boulevard South Las Vegas, NV The hotel has reserved a limited block of guest rooms at a special group rate of $259/night (USD) for a King Resort Suite and $379/night (USD) for a King Tower Suite plus applicable city/state taxes. There will be an additional charge of $50/ night (USD) for double queen bed accommodations at the Encore for weekdays and $70/night (USD) for weekends. Group rates will apply three days prior and three days following the course dates, based upon availability. To receive this group rate, you must make your reservations before the room block is filled or by the cut-off of September 5, 2017.

4 REGISTRATION FEES (in USD) On or Before Sept 6 After Sept 6 MD, PhD, DO $475 $550 Nurses, PA, NP, Other $350 $425 Registration fee includes tuition, Saturday morning Career Development session, comprehensive course syllabus (electronic), break refreshments, Saturday breakfast, and Saturday lunch. Visit the course website for more information on registering and our cancellation policy. CE.MAYO.EDU/LEUKEMIA2017 MAYO CLINIC COURSE DIRECTORS Lisa Z. Sproat, M.D., M.S.W. Ruben A. Mesa, M.D., F.A.C.P. Jeanne M. Palmer, M.D. Jeffrey A. Betcher, BS Pharm, BCOP MAYO CLINIC FACULTY Aref Al-Kali, M.D. Rochester, Minnesota Timothy G. Call, M.D. Rochester, Minnesota James M. Foran, M.D., F.R.C.P.C. Jacksonville, Florida Juan Gea-Banacloche, M.D. Tania Jain, M.B.B.S. Katalin Kelemen, M.D., Ph.D. Jose F. Leis, M.D., Ph.D. Mark R. Litzow, M.D. Rochester, Minnesota Sara E. Wordingham, M.D.

5 PROGRAM SCHEDULE FRIDAY, OCTOBER 6, :30 p.m. Registration and Refreshments 3:00 p.m. Welcome Announcements 3:15 p.m. Keynote Address: Chronic Lymphocytic Leukemia: Emerging Therapies and Highlights of Current Practice 4:00 p.m. Acute Myeloid Leukemia Case: An Interactive Case Presentation 5:00 p.m. Myelofibrosis Case: An Interactive Case Presentation 5:30 p.m. Break 5:45 p.m. Chronic Myeloid Leukemia: An Interactive Case Presentation 6:15 p.m. Chronic Lymphocytic Leukemia: An Interactive Case Presentation 7:15 p.m. Adjourn SATURDAY, OCTOBER 7, :00 a.m. Continental Breakfast for Career Development Session 7:30 a.m. 8:30 a.m. Career Development: Creating a Path to Academic Success Optional Morning Session (included in course registration fee; separate registration required) 8:00 a.m. Continental Breakfast 8:45 a.m. Announcements 9:00 a.m. Myelodysplastic Syndrome/Acute Myeloid Leukemia: Molecular Profile and Epigenetics 9:45 a.m. Myelodysplastic Syndrome/Acute Myeloid Leukemia: Emerging Therapies 10:30 a.m. Break 10:45 a.m. Myelodysplastic Syndrome: Practical Management 11:15 a.m. Acute Lymphoblastic Leukemia in Adults: Progress After All These Years 11:45 a.m. Approaching Challenging Conversations in Advanced Illness 12:15 p.m. Question and Answer 12:30 p.m. Lunch with the Experts 1:30 p.m. Myeloproliferative Neoplasms: Managing the Whole Patient with Chronic MPNs 2:00 p.m. Infectious Disease: Prophylaxis and Treatment 2:30 p.m. You Don t Have a Donor Now What? 3:00 p.m. Next Generation Sequencing in Hematologic Neoplasm: The Pathologist s Point of View 3:30 p.m. Question and Answer 4:00 p.m. Adjourn

6 MAYO CLINIC East Shea Boulevard Scottsdale, Arizona Mayo Clinic School of Continuous Professional Development ACUTE & CHRONIC LEUKEMIAS 2017 ENCORE AT WYNN LAS VEGAS LAS VEGAS, NEVADA OCTOBER 6 7, 2017 REGISTER NOW! For more information, contact Mayo Clinic School of Continuous Professional Development mca.cme@mayo.edu $75 DISCOUNT when you register online before September 6, 2017 CE.MAYO.EDU/LEUKEMIA Mayo Foundation for Medical Education and Research MC