MIP636- Mechanisms of Viral Infection and Disease

Transcription

1 MIP636- Mechanisms of Viral Infection and Disease Instructor Information: Required Texts: Course Description: Dr. Ken Olson Office Location: AIDL Foothills Campus Phone: Office Hours: by appointment Dr. Sandra L. Quackenbush Office Location: 315 Pathology Bldg Phone: Office Hours: by appointment None required. Electronic copies of course-related materials, such as peer-reviewed publications will be posted on RamCT. This graduate course will focus on the mechanisms by which viruses cause disease. Course Objectives or Course Learning Outcomes: Students will be able to describe viral evolution Students will be able to describe how viruses are transmitted and spread within the host and populations Students will be able to explain the mechanisms by which the host elicits an immune response Students will be able to describe the mechanisms by which viruses modulate the immune response Students will be able to describe the mechanisms by which viruses cause tissue damage and loss of function, inflammation and cancer Course Prerequisite MIP420 or MIP530 Credit Hours 4 Class Breakdown Lecture Hours: 3 Recitation: 1 Teaching Strategies Course Policies and Procedures: Total hours: 4 Teaching strategies for this course will be lecture, presentation of current literature and class discussions The course is designed to require two hours minimum outside work for each contact hours in achieving the learning objectives through the readings and presentation assignments. Attendance: Class attendance strongly advised. Academic Honesty: This course will adhere to the CSU Academic Integrity Policy as found in the General Catalog - 1.6, pages 7-9. ( FrontPDF/1.6POLICIES.pdf) and the Student Conduct Code ( ). At a minimum, violations will result in a grading penalty in this course and a report to the Office of Conflict Resolution and Student Conduct Services.

2 Late work & Educational Responsibility: All assignments for the week must be completed by the last day in the week unless an alternate due date has been previously approved or documentation has been provided for extreme circumstances. It is the student's responsibility to communicate with the instructor about extreme circumstances or questions concerning the assignment and their due dates. Grading Scale: Students will be evaluated and assessed using in class exam, oral presentation and written critique of an assigned paper and participation in discussions. This class uses a traditional A-F grading system. A % B % C % D % F- less than 61% Evaluation Breakdown: Midterm Examination Final Examination Paper presentation and critique Discussions Total: 30 points 35 points 25 points 10 points 100 points

3 MIP636- Mechanisms of Viral Infection and Disease Spring 2015 Wednesday and Friday 2:00-4:30 pm Pathology Room 109 Lecturer 1) Jan 21, 2015 (W) Introduction to course Olson Overview of viral structure and replication Wilusz 2) Jan 23, 2015 (F) Origin and emergence of viral diseases Olson 3) Jan 28, 2015 (W) Bioinformatics: tools for understanding Stenglein virus-host interactions 4) Jan 30, 2015 (F) Viral Epidemiology: an overview Moore 5) Feb 4, 2015 (W) Viral variation and evolution in viral pathogenesis Ebel 6) Feb 6, 2015 (F) Life of viruses in cells: entry/exit Perera 7) Feb 11, 2015 (W) Mechanisms of adaptive immunity Schenkel and evasion by viruses 8) Feb 13, 2015 (F) Mechanisms of innate immunity and evasion Blair by viruses 9) Feb 18, 2015 (W) Vaccines and innate immunity Dean 10) Feb 20, 2015 (F) Virus-induced apoptosis Clarke 11) Feb 25, 2015 (W) Overview of pathology Aboellail Experimental approaches to viral pathogenesis\ 12) Feb 27, 2015 (F) Virus-induced immunopathology Aboellail 13) Mar 4, 2015 (F) Virus induced immunosuppression; Akkina pathogenesis of AIDS

4 14) Mar 6, 2015 (W) Host factors in disease Schountz 15) Mar 11, 2015 (W) Viral oncogenesis- RNA viruses Quackenbush and DNA viruses 16) Mar 13, 2015 (F) Midterm exam 17) March Spring Break 18) Mar 25, 2015 (W) Viral encephalitis Bowen 19) Mar 27, 2015 (F) Alphaherpesvirus latency Cohrs 20) Apr 1, 2015 (W) Viral reproductive and congenital infections Bowen 21) Apr 3, 2015 (F) Viral respiratory diseases- influenza Landolt 22) Apr 8, 2015 (W) Viral enteric diseases MacNeil 23) Apr 10, 2015 (F) Mosquito-borne viral diseases Powers 24) Apr 15, 2015 (W) Vector biology and arboviruses Olson 25) Apr 17, 2015 (F) Innate immunity and the mosquito vector Blair 26) Apr 22, 2015 (F) Prion diseases Hoover 27) Apr 24, 2015 (F) Bats and zoonotic viral diseases Schountz 28) Apr 29, 2015 (W) Viral hepatitis Barton 29) May 1, 2015 (W) Rodent-borne zoonotic viral diseases Schountz 30) May 6, 2015 (W) Antiviral Therapy Geiss

5 mailto: 31) May 8, 2015 (F) Vaccine and Antiviral product development Pierro 32) Final Exam Olson/Quackenbush