CURRICULUM VITAE. Roanne K. Karzon, Ph.D.

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1 CURRICULUM VITAE Roanne K. Karzon, Ph.D. ADDRESS: Program in Audiology and Communication Sciences Washington University School of Medicine Campus Box 8042, 660 South Euclid Avenue St. Louis, MO Phone (314) (office) (314) (FAX) PRESENT POSITION: Assistant Clinical Professor (Adjunct) Program in Audiology and Communication Sciences Department of Otolaryngology Washington University School of Medicine St. Louis, MO 1997-present, Manager, Audiology, Cochlear Implant Program, Visual Assessment Laboratory, Sleep Diagnostic Center, St. Louis Children s Hospital. Clinical Assistant Professor, Department of Otolaryngology, Washington University School of Medicine. EDUCATION: Undergraduate 1974 B.A., Magna Cum Laude, Speech Pathology and Audiology, University of Connecticut, Storrs, CT. Graduate 1976 M.Ed., Speech Pathology and Audiology, University of Virginia, Charlottesville, VA Ph.D., Communication Sciences, Washington University, St. Louis, MO. ACADEMIC POSITIONS/EMPLOYMENT: Postdoctoral Research Scientist and Assistant

2 Professor, Central Institute for the Deaf, St. Louis, MO Assistant Professor of Clinical Otolaryngology/ Audiology, Department of Otolaryngology, Washington University School of Medicine 1993-present Clinical Assistant Professor of Audiology, Central Institute for the Deaf. Clinical Assistant Professor, Department of Otolaryngology, Washington University School of Medicine (Adjunct) UNIVERSITY / HOSPITAL / DEPARTMENTAL APPOINTMENTS AND COMMITTEES: Audiologist/Speech Pathologist, Cooper Medical Center, Camden, NJ Olin Fellow for predoctoral training in Communication Sciences, Central Institute for the Deaf, Washington University, St. Louis, MO Manager, Audiology, St. Louis Children's Hospital present Manager, Audiology and Cochlear Implant Program, Visual Assessment Laboratory, Sleep Diagnostic Center, 1983 Honors Defense Committee for Beth Lipincott (undergraduate), Linguistics Department, Washington University, St. Louis, MO Defense Committee for Jovo Dravekovich (Master's Degree), Engineering Department, Washington University, St. Louis, MO Defense Committee for Lynne Shields (Doctoral Defense), Communication Sciences, Washington University, St. Louis, MO Defense Committee for Joy Anita Haven (Doctoral Defense), Department of Psychology, Washington University, St. Louis, MO Independent study advisor for Nickey S. Martino, A retrospective study assessing the relative clinical value of performing VRA versus ABR on infants between the ages of seven and twelve months, Communication Sciences, Washington University, St. Louis, MO.

3 1994 Independent study advisor for Albert Zhao, Test-retest reliability of distortion product otoacoustic emissions in high-risk registry neonates, Communication Sciences, Washington University, St. Louis, MO Independent study advisor for Brandy R. Jones, Sensitivity and specificity of tympanometric gradient and middle ear resonance in young children and infants, Communication Sciences, Washington University, St. Louis, MO 1996 Independent study secondary advisor for Robin Hudson, Identification of delayed onset hearing loss in neonates given ototoxic medication, Communication Sciences, Washington University, St. Louis, MO Independent study secondary advisor for Julie Lyn Old, The effects of carboplatin on hearing sensitivity in children, Communication Sciences, Washington University, St. Louis, MO Independent study advisor for Dawn M. Carpenter, The reassessment of central auditory processing disorders in children 7 to 12 years of age, Communication Sciences, Washington University, St. Louis, MO Subcommittee member for the Task force on treatment outcome and cost effectiveness Birth to Kindergarten) of the American Speech-Language-Hearing Association, March 30 to April 1, 1996, Bethesda, MD Panelist for Expanding Your Horizons in Mathematics and Science Conference for the Math/Science Network of Greater St. Louis, March 12, Independent study advisor for Julie A. Wirth, The high risk register and identification of hearing impaired infants in an NICU, Communication Sciences, Washington University, St. Louis, MO Independent study advisor for Lisa Di Maria, Changes in the use of ABR testing for differential diagnosis of hearing loss from 1984 to 2002, Communication Sciences, Washington University, St. Louis, MO Independent study advisor for Julie Berron, Physical and perceived noise levels within the neonatal instensive care unit of St. Louis Children s Hospital, Communication Sciences, Washington University, St. Louis, MO Independent study advisor for Beth Knopf, Parental response to newborn hearing screening, Communication Sciences, Washington University, St. Louis, MO Advisory Board of Audiology Online to present.

4 2006 Scholarship Oversite Committee for Dr. Jennifer Dean, Pedatric Hematology/Oncology Fellow Capstone advisor for Kelly Clarke, Comparison of video and toy reinforcers to motivate infants/toddlers for hearing tests, Program in Audiology and 2007 Capstone advisor for Jamie Baum, Development of a high-frequency hearing loss questionnaire for children, Program in Audiology and Communications Sciences, Washington University, St. Louis, MO Ad hoc review for the International Journal of Audiology 2008 Capstone advisor for Toby Wilson, Efficacy of high-frequency tympanometry in infants birth to six months of age: A pilot study, Program in Audiology and 2008 Capstone secondary advisor for Amy M. Streufert, Quality of life measure for adolescents and children with hearing loss, Program in Audiology and 2009 Capstone advisor for Jamie Glater, Efficacy of 1000 Hz tympanometry in infants birth to 4 months of age: A follow up study, Program in Audiology and 2010 Capstone advisor for Megan Cahill, Efficacy of the speech intelligibility index as an intervention tool with pediatric cancer patients, Program in Audiology and 2011 Capstone advisor for Katherine Archibald Rapp, The efficacy of the speech intelligibility index as a counseling tool in pediatric patients, Program in Audiology and Communications Sciences, Washington University, St. Louis, MO Capstone advisor for Allyson Davis, Acceptance of earphones in children 12-to- 24 months of age during visual reinforcement audiometry, Program in Audiology and EXTRAMURAL ACTIVITIES 1983 Olin Conference Committee 1987, 1988 Olin Conference Coordinator

5 Institutional Review Board for the Protection of Human Subjects, Central Institute for the Deaf President Elect (2005), President (2006) and Past President (2007), Missouri Academy of Audiology CERTIFICATION Speech Pathology and Audiology (1978) by the American Speech-Language-Hearing Association (CCC-A/SLP). Current certification in audiology (CCC-A). Licensed as a Clinical Audiologist by the State of Missouri. HONORS AND AWARDS: 1974 Phi Beta Kappa, University of Connecticut 1974 Phi Kappa Phi, University of Connecticut 1976 Lychnos Society, University of Virginia Olin Fellowship, Washington University 2011 Editor s Award, American Journal of Audiology EDITORIAL RESPONSIBILITIES: 1984 Book Review for: Pediatric Audiology (1984). J. Jerger (Ed.), College-Hill Press. Appeared in The Volta Review, 87, Ad Hoc Reviewer for NIH epidemiology and disease control-2 Review Panel, Review Meeting June 28 to June 29, 1999, Old Town Alexandrea, VA Ad hoc review for Language, Speech, and Hearing Services in Schools Ad hoc review for PROFESSIONAL SOCIETIES AND ORGANIZATIONS: American Speech-Language-Hearing Association Missouri Speech-Language-Hearing Association Missouri Academy of Audiology RESEARCH SUPPORT: 1991 Gates, G.A. (PI) and Karzon, R.K. (Co-Investigator), Objective assessment of hearing loss in senile dementia.

6 Awarded by the Alzheimer's Disease and Related Disorders Program of the University of Missouri, $19, Karzon, R.K. (PI) and Arjmand, E.M. (Co-Investigator), 1994 Karzon, R. K. (PI) otoacoustic emissions screening in high-risk infants. Awarded by the American Hearing Research Foundation, $10,000 per year. TEACHING RESPONSIBILITIES: UNIVERSITY OF VIRGINIA 1976 Laboratory in Experimental Phonetics (Laboratory Instructor) WASHINGTON UNIVERSITY 1982, 1983 Language, Its Development and Impairment (Team-taught) Introduction to Communication Sciences and Disorders 1983 Introduction to Audiology Pediatric Audiology Lecture for Otolaryngology Residents Ad Hoc Lectures for Graduate Training Program of Central Institute for the Deaf 1992-Present 2003-Present Pediatric Audiology Monthly tutorial for the Developmental and Behavioral Focus Group of the Behavioral and Developmental Pediatrics Program. BIBLIOGRAPHY: Peer Reviewed Manuscripts 1. Karzon, R.G., and Niemoeller, A.F. (1983). A model for predicting hearing aid performance. Scandinavian Audiology, 12, Karzon, R.G. (1985). Discrimination of polysyllabic sequences by young infants. Journal of Experimental Child Psychology, 39, Karzon, R.G. (1985). Speech Development: Report of Working Group 4. In J.L. Lauter, J.D. Miller and D.R. Calvert (Eds.), Proceedings of the conference on the planning and production of speech in normal and hearing-impaired individuals. ASHA Reports, 15, Karzon, R.G. (1985). Women in Academics. In B.P. Davidson (Ed.), The Olin Network Newsletter, 1, 9-10.

7 5. Painter, C., Fredrickson, J.M., Kaiser, T., and Karzon, R. (1987). Human speech development for an implantable artificial larynx. Annals of Otology, Rhinology and Laryngology, 96, Kaiser, T.N., and Karzon, R.K. (1988). Biologic listening check. Hearing Instruments, 39, Karzon, R.G., and Nicholas, J.G. (1989). Syllabic pitch perception in 2- to 3-month-old infants. Perception and Psychophysics, 45, Lauter, J.L., and Karzon, R.G. (1990a). Individual differences in auditory electric responses. III. A replication, with observation of individual vs. group characteristics. Scandinavian Audiology, 19, Lauter, J.L., and Karzon, R.G. (1990b). Individual differences in auditory electric responses: comparisons of between-subject and within subject variability. IV. Latency-variability comparisons in early, middle, and late responses. Scandinavian Audiology, 19, Lauter, J.L., and Karzon, R.G. (1990). Individual differences in auditory electric responses: comparisons of between-subject and within-subject variability. V. Amplitude variability comparisons in early, middle, and late responses. Scandinavian Audiology, 19, Karzon, R.G. (1991). Validity and reliability of tympanometric measures for pediatric patients. Journal of Speech and Hearing Research, 34, Karzon, R.G., Garcia, P., Peterein, J.P. and Gates, G.A. (1994). Distortion Product Otoacoustic Emissions (DPOEs) in the Elderly. American Journal of Otology, 15 (5), Gates, G.A., Karzon, R.K., Garcia, P., Peterein, J. Storandt, M., Morris, J.C. and Miller, J.P.(1994) Auditory dysfunction in senile dementia of the Alzheimer's type. Archives of Neurology, 52(6), Popelka, G., Karzon, R.K., and Arjmand, E.M. (1994). Growth of the 2f 1 -f2 distortion product otoacoustic emission for low-level stimuli in human neonates. Ear and Hearing, 16, Popelka, G., Karzon, R.K., and Clary, R.A. (1998). Identification of Noise Sources That Influence Distortion Product Otoacoustic Emission Measurements in Human Neonates. Ear and Hearing, 19, Herrmann B.W., Karzon R., Molter D.W. (2005). Otologic and Audiologic Features of Nager Acrofacial Dysostosis. International Journal of Pediatric Otorhinolaryngology, 69, Lieu, J.C., Karzon, R.K., and Mange, C.C. (2006). Hearing Screening in the NICU: Follow-Up of Referrals. American Journal of Audiology, 15,

8 18. Karzon, R.K. and Lieu, J.C. (2006). Initial Audiologic Assessment of Infants. American Journal of Audiology, 15, Karzon, R.K. and Lieu, J.C. (2007). Response to Sauter. American Journal of Audiology, 16, Dean, J.B., Hayashi, S.S., Albert, C.M., King, A.A., Karzon, R., Hayashi, R.J. (2008). Hearing loss in pediatric oncology patients receiving carboplatin-containing regimens. Journal of Pediatric Hematology and Oncology, 30 (2), Kolinsky, D.C., Hayashi, S.S., Karzon, R.K., Mao, Jingnan, M., Hayashi, R.J. (2010) Late onset hearing loss: A significant complication of cancer survivors treated with cisplatin containing chemotherapy regimens, Journal of Pediatric Hematology and Oncology, 32, Lieu, J.E., Tye Murray, N., Karzon, R.K., Piccirillo, J.F. (2010) Unilateral hearing loss is associated with worse speech-language scores in children. Pediatrics, 125(6), Karzon, R. K. and Banerjee, P. (2010). Animated toys versus video reinforcement in 16- to 24- month-old children in a clinical setting. The American Journal of Audiology, In Press. 24. Marhall, BA, Permutt, MA, Paciorkowski, AR, Hoekel, J, Karzon, R, et al. (2013) Phenotypic characteristics of early Wolfram syndrome, Orphanet Journal of Rare Diseases, Apr 27; 8(1): 64 [Epub ahead of print] 26. Karzon, R. K. and Hullar, T.E. (2013) Audiologic and Vestibular Findings in Wolfram Syndrome Ear and Hearing, Nov-Dec; 34(6): Lieu, J. E. C., Karzon, R.K., Ead, B., Murray, N. T. (2013) Do Audiologic Characteristics Predict Outcomes in Children with Unilateral Hearing Loss? Otology and Neurotology, Dec; 34(9):