ANNUAL CURRICULUM. Lesson 1 : Testicular activity and its control. Experiment : Dissection of mouse reproductive system

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1 Class : S5 Subject : BIOLOGY Teacher name: AMILHAT CURRICULUM 2012/2013 European section : english Teaching language: english Periods: 2 or 1h30 IGCSE preparation for IGCSE biology (Edexcel) 12h yearly CERTIFICATION OBJECTIVES ANNUAL CURRICULUM 1 ST PART : HORMONAL AND NERVOUS COMMUNICATION September (2 weeks) I. Nervous system Hormonal system 2 nd PART : HUMAN REPRODUCTION Lesson 1 : Testicular activity and its control September Experiment : Dissection of mouse reproductive system Doc. 1a : Human male reproductive system doc. 1b : function of reproductive system organs I. Sperm cell and testosterone production during life 1. sperm cell production Experiment : Microscopic observation of testis slide and sperm cell in epidydimis Experiment : Microscopic observation of sperm cell in epidydimis October Doc. 2 : organisation of a sperm cell Doc. 3 : testis section autoradiography 2. testosterone : a male hormon 3. testosterone production Document 4 : Blood concentration of testosterone during 15 days (above) and one day (below) November Regulation of blood concentration of testosterone 1. Hypophysis controls testis activity Doc. 5 : consequences of hypophysis ablation on male activity Doc. 6 : concentration of hypophyseal hormons in function of time Doc. 7 : role of hypophyseal hormons on testicular functioning 2. Hypothalamus controls hypophysis activity

2 Doc. 7 : production of hypophyseal hormons after GnRH injection Doc. 8 : consequences of testis castration 3. a negative feedback exerced by testosterone on pituitary gland and HT Conclusion : construction of a sketch about testis activity and its control December Lesson 2 : To understand female reproductive cycle Doc. 1a : Human female reproductive system Doc. 1b : function of reproductive system organs I. the changes at puberty Female cyclic functioning 1. ovarian cycle Experiment : Microscopic observation of ovaries during cycle doc. 2 : picture of De Graaf follicle to label 2. uterian cycle Experiment : Microscopic observation of uterus during cycle doc. 3: changes in the lining of uterus 3. Cervical mucus cycle 4. Production of ovarian hormons Cf. doc. 4 : Changes in ovarian hormons concentration during menstrual cycle I Control of female cyclic functioning by HT pituitary gland Conclusion : construction of sketchs about female cyclic activity and its control Lesson 3 : From fertilization to pregnancy I. Fertilization and beginning of pregnancy 1. how to manage a fertilization Experiment : Microscopic observation of a Sea urchin fertilization (?) 2. fertility period From pregnancy to childbirth Experiment : Use of pregnancy test (?) Revise human reproduction and coordination chapter for mid-january

3 Mid-january Semestrial exam on human reproduction and coordination Lesson 4 : Birth control and Assisted reproductive technology I. Birth control 1. methods that avoid fertilization 2. methodes using sexual hormons Paper report and presentation of ART and STD by pupils To make a slideshow presentation Assisted reproductive technology 1. pregnancy supervision 2. Infertility treatments I STD (sexually transmitted diseases) 3 RD PART : GENETICS / INHERITANCE date Programmation Homework Lesson 1 : Unit and diversity of human beings february I. Resemblances parents - children A. transmission of resemblances B. Influence of life habits The structures carrying inherited features A. Cellular Localisation Document 1 : nucleus transfer between 2 individuals of the same species B. The nucleic structures carrying inherited features 1. Chromosomes Doc. 2 : Chromosomes and genetic information 2. Composition of chromosomes Experiment : DNA Extraction of different living beings 3. relation between DNA and chromosome Document 3 : relation DNA - Chromosome To make a paper report for March Test n 1 : Unit and diversity of human beings I DNA : a molecule that carries a genetic information Document 4 : a gene transfer between a human cell and a bacterian cell

4 IV. DNA : an informative molecule 1. Organisation of DNA molecule Use of rastop software Doc. 5 : DNA structure 2. DNA a coding molecule Experiment with Anagene sofware (not possible) to compare ABO gene for differents human beings (A and B blood groups) Doc. 6a : ABO gene and blood group feature Doc. 6b : Comparison of ABO gene for differents human beings (A and B blood groups) 3. genes and alleles of a gene Doc. 7 : genes and alleles of a gene 4. mutations Document 8 : Mutations Conclusion lesson 1 Test n 2 : Unit and diversity of human beings April Lesson 2 : the maintaining of chromosomes set (or complement) during celldivision (mitosis) I. Importance of cell division (mitosis) Document 1 : Importance of mitosis in the functioning of the organism Mechanisms of chromosomes distribution (sharing out) during cell division (mitosis) Experiment : Microscopic Observation of mitosis figures in an active division area of hyacinth root Comparison with differents steps of Ascaris mitosis Doc. 2a and 2b For Document 2a : stages in mitotic division of a cell Document 2b : Different steps of mitosis (plant cell with 2n = 6) I duplication of chromosomes Document 3 : Evolution of DNA amount in a cell in function of time Document 4 : Conservation of the chromosome complement during cell division Conclusion Self-assessment questions (1 7) on chromosomes and cell divisions (IGCSE preparation)

5 may Lesson 3 : Inheritance and original transmission of hereditary features I. Genotype and phenotype Document 1 : Family tree Original chromosomes transmission from parents to children 1. Alleles transmission Document 1 : Family tree Document 2 : Rhesus factor 2. Gametes formation and alleles transmission Document 3 : Chomosomes complement of a sperm cell and an egg cell Experiment : Microscopic Observation of meiosis figures in Lily anther Document 4 : Steps of meiosis Document 5 : Chromosomes sharing out during gametes formation. 3. meeting of gametes during fertilization Experiment : Modelization of Original transmission of alleles during gametogenesis and fertilization Test n 3 : Chromosomes and cell divisions I Chromosomal anomaly Self-assessment questions (8 13) on chromosomes and cell divisions (IGCSE preparation) Genetic exercise for IGCSE preparation May Lesson 4 : Crossings and genetic diversity I. Crossing of 2 pure-breeding living beings which differs by one feature (monohybrid cross) Crossing of 2 pure-breeding living beings which differs by 2 features (dihybrid cross) 1. Independent genes 2. Linked genes Experiment : Observation and counting of fruit fly offspring I Natural selection and genetic drift VACATION End of May : IGCSE preparation exam : - nature and variety of living organisms - structures and functions of living organisms - reproduction and inheritance - ecology and environment - use of biological resources

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