American University of Beirut Faculty of Health Sciences Medical Laboratory Sciences Program

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1 P 1 of 5 American University of Beirut Faculty of Health Sciences Medical Laboratory Sciences Program () Fall Semester Name Rolla Al-Khatib Course Credits: 3 credits Office Hours: TWRF: 10:00 a.m.-11:00 a.m. Meeting Location Van Dyck, or by appointment MTW Nabil Boustani Office Location: Van Dyck, Rm 322 Meeting Time: MTW: 02:00 p.m. 02:50 p.m. Extension ra03@aub.edu.lb COURSE DESCRIPTION is intended to introduce students to fundamental concepts in hematology, including normal physiology of blood, development of blood cell elements in the erythrocytic, leukocytic and megakaryocytic cell lines as well as blood cell disorders, with a special emphasis on anemias. The course covers the different causes of anemias and prepares students to the diagnosis of the different types of anemia based on laboratory findings. It is based on lectures, discussions, demonstrations and case studies. GENERAL INSTRUCTIONAL OBJECTIVES By the end of the course, students will be able to: - Know the various elements of the blood; - Understand the function of each type of blood cell; - Know the basic elements of the bone marrow; - Understand the principles of erythropoiesis, myelopoiesis and megakaryopoiesis. - Understand the basic mechanisms of anemia; - Know the different lab. findings associated with the different types of anemia; - Describe the different types of diseases associated with abnormal clotting. STUDENTS LEARNING OUTCOMES By the end of the course, students will be able to: - Describe the various elements of the blood; - Explain the function of each type of blood cell; - Describe the different types of blood cells in the bone marrow; - Describe the formation and development of the different types of blood cells in the bone marrow; - Classify the different types of anemia; - Diagnose the different types of anemia based on laboratory findings; - Describe the different types of diseases associated with abnormal clotting.

2 P 2 of 5 REFERENCES * Moodle Course * Clinical Hematology E.Anne Stiene-Martin Cheryl A.Lotspeich-Steininger John A. Koepke * Interesting Hematology Links STUDENT ASSESSMENT Grades for this course will be based on the following criteria: Quiz I 30 % Quiz II 35 % Final exam 35 % N.B.: The passing grade for the course is 60 COURSE SYLLABUS Week Topic Activities Reading W E E K 1 M AUG 29 * Introduction Moodle (Syllabus) T AUG 30 * Introduction to Hematology * Composition of blood (RBC(s), WBC(s) and platelets). W AUG 31 * Anticoagulants * Sources of blood for hematological tests * Manual blood film preparation * Staining of the blood film W E E K 2 M SEP 5 * Tools used to study blood cells Moodle (Lecture) CBC count WBC count RBC count T SEP 6 * Hemoglobin (Spectrophotometric determination of Hb concentration) * Hematocrit (Centrifuged HCT) Moodle (Lecture & Table)

3 P 3 of 5 W SEP 7 * Red blood cell indices (MCV, MCH, MCHC, RDW) Moodle (Lecture & Table) W E E K 3 M SEP 12 * Vacation T SEP 13 * Vacation W SEP 14 * Techniques for cell counting Moodle (Lecture) W E E K 4 M SEP 19 * Erythrocyte Sedimentation Rate T SEP 20 * Erythrocyte, production, maturation and destruction * Reticulocyte count Moodle (Lecture) W SEP 21 * Structure of hemoglobin * Normal hemoglobin variants * Hemoglobin synthesis and function W E E K 5 M SEP 26 * Alterations of the red blood cells Hematology atlas.com and Presentation) T SEP 27 * Alterations of the red blood cells Hematology atlas.com and Presentation)) W SEP 28 * Abnormal red blood cell inclusions Hematology atlas.com and Presentation W E E K 6 M OCT 3 * Abnormal red blood cell inclusions Hematology atlas.com and Presentation) T OCT 4 * Structure of the red blood cell and red blood cell membrane W OCT 5 * Classification of white blood cells Moodle (Lecture & Power * Differential count Point) W E E K 7 M OCT 10 * Quiz I T OCT 11 W OCT 12 * * * Vacation Neutrophils Eosinophils Basophils Moodle (Lecture & Power Point Presentaion)

4 P 4 of 5 W E E K 8 M OCT 17 * Correction of Quiz I T OCT 18 * Monocytes Moodle (Lecture & Power * Lymphocytes Point Presentaion) W OCT 19 * Organs involved in blood cell formation * Structure of the bone marrow * Stem Cells Moodle (Lecture) W E E K 9 M OCT 24 * Other elements of the bone marrow Moodle (Lecture & Power T OCT 25 * Other elements of the bone marrow Moodle (Lecture & Power W OCT 26 * Erythropoiesis Moodle (Lecture & Power W E E K 10 M OCT 31 * Myelopoiesis Moodle (Lecture & Power T NOV 1 * Thrombopoiesis Moodle (Lecture & Power W NOV 2 * Introduction to anemias Moodle (Lecture) W E E K 11 M NOV 7 * Iron deficiency anemia (Introduction) Moodle (Lecture) T NOV 8 * Iron deficiency anemia (Diagnosis) W NOV 9 * Iron deficiency anemia (Case Study) W E E K 12 M NOV 14 * thalassemia (Introduction) Moodle (Lecture ) M T NOV 15 * thalassemia (Diagnosis ) Moodle (Lecture ) W NOV 16 * thalassemia (Treatment ) Moodle (Lecture W E E K 13 M NOV 21 * Quiz II T NOV 22 * Vacation W NOV 23 * Sickle cell anemia Moodle (Lecture)

5 P 5 of 5 W E E K 14 M NOV 28 * Megaloblastic anemia Moodle (Lecture) T NOV 29 * Coagulation I Moodle (Lecture) W NOV 30 * Coagulation II Moodle (Lecture) W E E K 15 M DEC 5 * Correction of Quiz II T DEC 6 * Revision Session COURSE POLICY 1. Attendance: you are expected to attend all classes and participate in class activities. If you miss a class, it is your responsibility to make up for the material missed, and inquire about any announcements made. If you miss more than one fifth of class sessions, you are subject to withdrawing from the course with a-wgrade. Please refer to the AUB catalogue. 2. Exams: Examinations must be taken as scheduled. Make up exams will not be given unless a valid excuse is given. Only authorized medical reports will be accepted. (AUBMC/ Infirmary) 3. Withdrawal date: Please observe withdrawal dates set by the Registrar s Office. 4. communication: I will be ing you on regular basis throughout the semester. You are required to check your s regularly. 5. Moodle: The course material and assignments are posted on Moodle. Students are held accountable for checking the Moodle course on regular basis. 6. Academic integrity: Cheating and plagiarism will not be tolerated. Review the Student Code of Conduct in your handbook and familiarize yourself with definitions and penalties. If you re in doubt about what constitutes plagiarism, ask your instructor because it is your responsibility to know. The American University of Beirut has a strict anti-cheating policy. Penalties include failing marks on the assignment in question, suspension or expulsion from University and a permanent mention of the disciplinary action in the student s records. 7. Special needs: AUB strives to make learning experiences as accessible as possible. If you anticipate or experience academic barriers due to a disability (including mental health, chronic or temporary medical conditions), please inform me immediately so that we can privately discuss options. In order to help establish reasonable accommodations and facilitate a smooth accommodations process, you are encouraged to contact the Accessible Education Office: accessibility@aub.edu.lb; , x3246; West Hall, 314.