Koostas: Anneli Aus Laboriarst Allkiri Ees- ja perekonnanimi Ametikoht kuupäev

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1 Kinnitas: Elektroonselt Katrin Reimand Osakonnajuhataja kinnitatud Koostas: Anneli Aus Laboriarst Allkiri Ees- ja perekonnanimi Ametikoht kuupäev Haematology reference values Analyte Age Sex Value Unit Reference Abbreviation Prothrombin time All M/F > 70 % 1 P-PT International 18y M/F 0,80-1,20 1 normalized ratio 0d - <3d 1,15-1,35 9 INR 3d - <1m 1,05-1,35 1m - <1y 0,86-1,22 1y - <6y 0,92-1,14 6y - <11y 0,87-1,20 11y - <18y 0,97-1,30 Activated partial 18y M/F 28,9 38,1 sec 1 thromboplastin time 0d - <3d 34,3-44,8 9 P-APTT 3d - <1m 29,5-42,2 1m - <1y 35,1-46,3 1y - <6y 33,6-43,8 6y - <11y 31,8-43,7 11y - <18y 33,9-46,1 Thrombin time All M/F < 21 sek 1 P-TT Fibrinogen 18y M/F 2,0-4,0 g/l 1 P-Fibr 0d - <3d 1,92-3,74 9 3d - <1m 2,83-4,01 1m - <1y 0,82-3,83 1y - <6y 1,62-4,01 6y - <11y 1,99-4,09 11y - <18y 2,12-4,33 Factor VII 18y M/F % 1 P-FVII 0d - <3d d - <1m m - <1y y - <6y y - <11y y - <18y Factor VIII 18y M/F % 1 P-FVIII 0d - <3d d - <1m m - <1y y - <6y Page 1 of 8

2 6y - <11y y - <18y Factor IX 18 y M/F % 1 P-F IX 0d - <3d d - <1m m - <1y y - <6y y - <11y y - <18y Factor XI 18a M/N % 1 P-FXI 0p - <3p p - <1k k - <1a a - <6a a - <11a a - <18a Factor VIII inhibitor Factor IX inhibitor All M/F BU 1 P-FVIII inh, FIX inh Factor inhibitor screening All M/F 1 P-F inh screen Von Willebrand factor All M/F % 1 P-vWF Free Protein S 18y M % 1 P-fPS F d - <3d d - <1m m - <1y y - <6y y - <11y y - <18y Protein C 18y M/F % 1 P-PC 0d - <3d d - <1m m - <1y y - <6y y - <11y y - <18y Activated protein C resistance All M/F 120 sec 1 P-APCR Antithrombin III 18y M/F % 1 Page 2 of 8

3 P-ATIII 0d - <3d d - <1m m - <1y y - <6y y - <11y y - <18y D-dimer 18y M/F < 0,5 µg/ml 1 P-DD 0d - <3d < 2,47 9 3d - <1m < 2,74 1m - <1y < 0,42. 1y - <6y < 0,53 6y - <11y < 0,56 11y - <18y < 0,39 Lupus sensitive All M/F APTT (31,4 43,4) sec 1 P-PTT-LA Lupus anticoagulant All M/F 1 P-LA (normalized ratio < 1,2 Low molecular heparin P-LMWH Rivaroxaban P-RXN Page 3 of 8 All All M/F M/F 0,5-1,0 3-4 h after dosage; 0-0,1 no treatment Missing in normal plasma Result depends on dosage, time of sampling etc. IU/mL 1 ng/l 12 Reptilase time All M/F <20 sec 1 P-RT Ristocetin cofactor activity All M/F Cut off for von Willebrand disease < 40 % 10 P-vWF:RCo Plasminogen All M/F % 1 P-Plasm Platelet function test sec All M/F with epinefrin 14 B-PFA-Col/Epi Platelet function test with ADP B-PFA-Col/ADP Platelet function test with P2Y12 B-PFA-P2YP12 All M/F All M/F 106 sec 14 sec Erythrocyte 17y - <51y F < 12 mm/h 3 11

4 sedimentation rate 51y - <61y < 19 B-ESR 61y - <70y < y < 35 17y - <51y M < 10 51y - <61y < 12 61y - <70y < y < 30 COMPLETE BLOOD COUNT WITH 5-DIFF B-CBC-5DIFF Red blood cells 18y F 3,9-5, /L 4 B-RBC M 4,2-5,7 0d - <7d M/F 4,0-6,6 5 7d - <14d 3,9-6,3 14d - <1m 3,6-6,2 1m - <2m 3,0-5,4 2m - <3m 2,7-4,9 3m - <6m 3,5-5,2 6m - <3y 3,5-5,6 3y - <12y 3,8-5,6 12y - <15y M 4,4-5,7 15y - <18y 4,5-6,0 12y - <18y F 4,0-5,6 White blood cells 21y M/F 3,5-8, /L 4 B-WBC Birth 9,0-30,0 8 <12h 13,0-38,0 12h - <1d 9,4-34,0 1d - <8d 5,0-21,0 8d - <15d 5,0-20,0 15d - <2m 5,0-19,5 2m - <1y 6,0-17,5 Page 4 of 8 1y - <3y 6,0-17,0 3y - 5y 5,5-15,5 5y - <7y 5,0-14,5 7y - <9y 5,4-13,5 9y - <11y 4,5-13,5 11y - <17y 4,5-13,0 17y - <21y 4,5-11,0 Hemoglobin 18y F g/l 4 B-Hb M d - <7d M/F d - <14d d - <1m m - <2m

5 2m - <3m m - <6m m - <3y y - <12y y - <15y M y - <18y y - <18y F Hematocrit 18y M % 4 B-Hct F d - <7d M/F d - <14d d - <1m m - <2m m - <3m m - <6m m - <3y y - <12y y - <15y M y - <18y y - <18y F Platelets B-PLT All M/F /L 4 Mean cell volume 18y M/F fl 4 B-MCV 0d - <7d d - <14d d - <1m m - <2m m - <3m m - <6m m - <3y y - <12y y - <18y Mean cell 4 hemoglobin 18y M/F pg B-MCH Mean cell 18y M/F g/l 4 hemoglobin 0d - <7d concentration 7d - <1m B-MCHC 1m - <3m m - <6m m - <3y y - <12y y - <18y RDW-CV 18y M/F 11,6-14,0 % 3 B-RDW-CV 0d - <18y Page 5 of 8

6 Reticulocytes 18y M/F 0,5-2,5 % 3 B-Ret % B-Ret # 10 9 /L Neutrophils M/F 40,0-80,0 % 3 21y B-Neut% 2,0-7, /L B-Neut# Birth 6,0-26,0 8 <12h 6,0-28,0 12h - <1d 5,0-21,0 1d - <8d 1,5-10,0 8d - <15d 1,0-9,5 15d - <2m 1,0-9,0 2m - <7m 1,0-8,5 7m - <5y 1,5-8,5 5y - <9y 1,5-8,0 9y - <17y 1,8-8,0 17y - <21y 1,8-7,7 Band neutrophils 18y M/F 0-5,0 % 3 Lymphocytes 21y M/F 20,0-40,0 % 3 B-Lymph% 1,0-3, /L B-Lymph# 0h - <12h 2,0-11,0 8 12h - <1d 2,0-11,5 1d - <15d 2,0-17,0 15d - <2m 2,5-16,5 2m - <7m 4,0-13,5 7m - <1y 4,0-10,5 1y - <3y 3,0-9,5 3y - <5y 2,0-8,0 5y - <7y 1,5-7,0 7y - <9y 1,5-6,8 9y - <11y 1,5-6,5 11y - <17y 1,2-5,2 17y - <21y 1,0-4,8 Monocytes B-Mono% B-Mono# Eosinophils B-Eo% B-Eo# Page 6 of 8 18y M/F 2,0-10,0 % 3 0,2-1, /L 0d - <7d 0,5-1,7 5 7d - <14d 0,3-1,3 14d - <3m 0,5-1,8 3m - <6m 0,2-1,6 6m - <3y 0,2-1,4 3y - <12y 0,1-1,1 12y - <18y 0,0-1,0 18y M/F 1,0-6,0 % 3 0,0-0, /L 0d - <7d 0,2-0,7 5 7d - <14d 0,2-0,8

7 Basophils B-Baso% B-Baso# Page 7 of 8 14d - <3m 0,2-0,6 3m - <6m 0,0-1,1 6m - <3y 0,0-1,0 3y - <12y 0,0-0,7 12y - <18y 0,0-0,7 18y M/F 0-1,0 % 3 0-0, /L 0d - <7d 0-0,3 5 7d - <18y 0-0,2 CEREBROSPINAL FLUID Leukocytes CSF-WBC Erythrocytes CSF-RBC 16y M/F /L 6 0d - <2m <27 2m - <16y <7 18a 0 Newborn preterm (<7d) <1000 Newborn term (<7d) <800 Neonate (7-30d) <50 3m - <18y <5 CEREBROSPINAL FLUID MICROSCOPY CSF-Diff Lymphocytes 18y M/F % 6 Monocytes 3-37 Neutrophils 0-2 Lymphocytes Neonate (<30d) 2-38 Monocytes Neutrophils 0-8 Histiocytes 1-9 URINE TEST STRIP Specific gravity U-SG strip 18y M/F ph U-pH strip 4,8 7,4 Leukocytes U-WBC strip (< 10 x 10 6 /L) Erythrocytes U-RBC strip (< 5 x 10 6 /L) Nitrite U-Nit strip Protein U-Pro strip (<0,1 g/l) Glucose U-Gluc strip (<1,7 mmol/l) 7 13

8 Ketone U-Ket strip (<0,5 mmol/l) Urobilinogen U-Ubg strip (<17 µmol/l) Bilirubin U-Bil strip (<3,4 mmol/l) URINE MICROSCOPY Erythrocytes U-ERY All M/F <4 /hpf Leukocytes M <2 U-WBC F <4 Hyaline cast U-hyaline cast M/F Diagnostica Stago methodology, 2015/ Lewis SM, Bain BJ, Bates I. Dacie and Lewis Practical Haematology, Nordic Reference Interval Project, Calgary Laboratory Services, CBC Reference values, CLSI H56-A, European Urinalysis Guidelines, Greer JP, Arber DA, Glader B et al. Wintrobe s Clinical Hematology, Diagnostica Stago methodology, Chrono-Log Ristocetin cofactor assay methodology, 07/ Innovance PFAP2Y methodology, Diagnostica Stago methodology, Roche Urisys teststrips methodology, Dade PFA Collagen/EPI Test Cartidge and Dade PFA Collagen/ADP Test Cartidge methodology, 2012 Page 8 of 8

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