Reduce feed & production costs through CIBENZA DP100
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1 Reduce feed & production costs through optimized amino acid AVAILABILITY CIBENZA DP100
2 WHAT IS CIBENZA DP100? CIBENZA DP100 feed additive from Novus is an intrinsically heat stable, potent protease enzyme feed additive that optimizes the digestibility of proteins in poultry feed ingredients. Benefits in Broiler and Layer Diets Reduced cost of feed and meat/egg production by: Lowering inclusion level of costly protein sources Optimizing use of lower digestibility feed ingredients Optimizes amino acid digestibility and increased metabolizable energy Better production performance due to: Improved protein digestibility Improved energy digestibility Sustaining optimum gut health Reduction in hindgut fermentation and reducing nitrogen waste Ingredient risk management through: Introduction and/or increased use of cost-effective, locally available alternative feed ingredients Minimizing effects of anti-nutritional factors (ANF) in feed ingredients by directly degrading them or by increasing their exposure to endogenous enzymes
3 CIBENZA DP100 Characteristics Broad-spectrum protease that works on all protein sources Protease activity: 600,000 units/gram (Novus standard procedures) An Economic Advantage Commercial trials have confirmed that after reducing dietary amino acids, supplementing the diet with CIBENZA DP100 reduced production cost by as much as 4.4 cents/kg live weight, and maintained growth performance (Table 1). TABLE 1. CIBENZA DP100 Commercial Broiler Trial in Brazil Treatment Number of Cost of Barns BWG Adjusted Productivity Production (50,000 (g/d) FCR Index (USD/kg birds/barn) Live Bird) Control DP Cost Reduction of USD/kg Live Bird CIBENZA DP100 improves the digestibility of all feed protein sources, allowing for alternative ingredient use and feed cost reduction strategies (Figure 1) Figure 1. CIBENZA DP100 Improves In vitro Protein Digestibility of All Feed Ingredients Tested Release of Amino Acids from Feedstuff Soybean Meal Canola Meal Cottonseed Meal DDGS Corn Wheat Lupins Poultry Meal Meat & Bone Meal Fish Meal Feather Meal Blood Meal NegControl CIBENZA DP100 Protease B Source: Yan, et al., 2011
4 Performance and Health By improving the digestion of proteins and amino acids, CIBENZA DP100 helps make valuable nutrients more available to the animals for growth and performance, while minimizing negative effects of undigested protein in the hind gut (Figures 2-5). By doing so, CIBENZA DP100 reduces negative impact of ANF on gut brush border and increases available nutrients to the villi, therefore improving overall gut health and morphology. Weight Gain (kg) Figure 2. Weight Gain of Chickens from 1 to 48 Days 2.413a 2.309b 2.418a 2.372ab 2.436a 2.404a Carcass Yield (%) Figure 3. Carcass Yield and Breast Meat Yield of Broilers +Protease +Protease Breast Yield (%) 2.25 Low protein & amino acids Average protein & amino acids High protein & amino acids P< Low protein & amino acids Average protein & amino acids High protein & amino acids 31 *P<0.01 Clostridium perfringens (log cfu) Figure 4. Clostridium perfringens Counts in the Ileum at 15 Days of Age b Source of variation Value Crude Protein 0,128 Protease 0,107 PB x Protease 0,043 a b Value crypt: villus Figure 5. Cibenza DP100 Improves the Crypt:Villus after 14 Days of Age Source of variation Value Crude Protein 0,821 Protease 0,054 PB x Protease 0, a Control High Protein 0.00 Control High Protein Fig 2-5 Source: Yan, et al., 2011
5 Managing Risks Posed by Anti-Nutritional Factors Many anti-nutritional factors such as Glycinin and ß-Conglycinin, are proteins, and can adversely affect ingredient quality and animal performance. CIBENZA DP100 degrades these factors and minimizes their presence, ensuring high quality feed (Figure 6). Figure 6. Hydrolyzing Ability of CIBENZA DP100 on Soybean Allergenic Proteins % Anti-nutritional Factor % -94.7% -88.9% 0 Glycine ß-Conglycinin Control CIBENZA DP100 Source: Wang, et al., 2011a
6 Appearance: Light brown dry powder Odor: Neutral CIBENZA DP100 Description Packaging: 25kg bag Shelf Life: Minimum 24 months Dose: g/ton of feed OR as directed by a poultry nutritionist Ordering Information Novus has dedicated sales and technical services professionals ready to assist you. Please contact your Novus Sales Representative or contact Novus Customer Service at Novus International, Inc. 20 Research Park Dr. St. Charles, MO Product not available in all countries. NOTICE: While the information contained herein ( Information ) is presented in good faith and believed to be correct as of the date hereof, Novus International, Inc., does not guarantee satisfactory results from reliance upon such Information, disclaims all liability for any loss or damage arising out of any use of this Information or the products to which said Information refers and MAKES NO REPRESENTATIONS OR WARRANTIES, EITHER EXPRESS OR IMPLIED, OF MERCHANTABILITY, FITNESS FOR A PARTICULAR PURPOSE OR OF ANY OTHER NATURE WITH RESPECT TO THE INFORMATION OR PRODUCTS, except as set forth in Novus s standard conditions of sale. Nothing contained herein is to be construed as a recommendation to use any product or process in conflict with any patent, and Novus International, Inc., makes no representation or warranty, express or implied, that the use thereof will not infringe any patent. and CIBENZA are trademarks of Novus International, Inc., and are registered in the United States and other countries. TM SOLUTIONS SERVICE SUSTAINABILITY is a trademark of Novus International, Inc Novus International, Inc. All rights reserved. 3779_v1_EN_NEA_APEC
Reduce Feed & Production Costs Through Optimized Amino Acid Availability CIBENZA DP100
Reduce Feed & Production Costs Through Optimized Amino Acid Availability CIBENZA DP100 WHAT IS CIBENZA DP100? CIBENZA DP100 protease enzyme from Novus is an intrinsically heat stable, potent protease enzyme
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