Extent and Distribution of White Matter Hyperintensities in Normal Aging, Mild Cognitive Impairment and Alzheimer s s Disease
|
|
|
- Valerie Jackson
- 5 years ago
- Views:
Transcription
1 Extent and Distribution of White Matter Hyperintensities in Normal Aging, Mild Cognitive Impairment and Alzheimer s s Disease Department of Neurology and Center for Neuroscience University of California at Davis Mitsuhiro Yoshita, Evan Fletcher, Oliver Martinez, Mario Ortega, Bruce Reed, Dan Mungas and Charles DeCarli
2 Object & Background Mild Cognitive Impairment Normal Aging (MCI) Alzheimer s Disease (NA) (AD) White Matter Hyperintensites (WMH) How different in Extent and Distribution
3 Subject Demographics AD MCI NA Number (F/M) 26 (16/1) 29 (12/17) 33 (23/1) Age (y) 79.6 ± 6.8 * 74.6 ± ± 8.1 range Education (y) 11.7 ± ± ± 5.8 range MMSE 19.5 ± 6.8 a 26.6 ± ± 2.7 range Vascular risk score range Brain volume (%) 77.3 ± 4.2 b 8.7 ± ± 4.3 WMH volume (%) 1.33 ± 1.3 c.92 ± ±.67 Data represented as mean ± standard deviation. * p <.1 between AD and NA, a p <.1 between AD and others. b p <.1 between AD and others, c p <.1 between AD and NA.
4 Image Analysis Methods Schema for WMH segmentation and nonlinear transformation for mapping DeCarli C, et al. Stroke 5. A A Composite image P P
5 ROI on 3-D 3 D WMH maps Pa Pb Pp Po Po Pp Pb Pa Cg Cs Cg (A) Cs (B) ROI volume (mm 3 ) : Cg: 263, Cs: 5, Pa: 1325, Pb: 319, Pp: 2385, Po: 983. Abbreviations: Cg: genu of corpus callosum, Cs: splenium of corpus callosum, Pa: anterior periventricular region, Pb: body of periventricular region, Pp: posterior periventricular region, Po: occipital periventricular region. We computed the number of voxel of WMH in each ROI, and calculated percentage of voxel which have WMH in each ROI of each subject.
6 Statistical Analysis 1. Groups were compared using analysis of variance (ANOVA) or Kruskal-Wallis test as appropriate according to the distribution of the data, with post hoc analysis. 2. Correlations were evaluated by Spearman s ranks correlation test. 3. Results are expressed as mean values ± standard deviation. 4. A p value less than.5 was considered significant. 5. Data were analyzed using the Statistical Package for Social Sciences (SPSS for Windows, version 12.; SPSS Inc, Chicago, IL).
7 WMH frequency maps in all subjects (A-1) X= (A-2) X= (B-1) 6 Z= (B-2) Z= (C-1) - 6 Y= (C-2) - 6 Y= (D) P A
8 3-D D WMH frequency maps in each group (A) (B) (C) Three-dimensional reconstruction of the WMH (orange) and ventricular (grey) maps. Orange color indicate the frequency of voxels containing the WMH more than 1%. (A): group of NA (B): group of MCI (C): group of AD
9 Group difference of WMH severity in each ROI (A): Periventricular region (%) * * ** Anterior Body Posterior Occipital (B): Corpus callosum region (%) * Genu * Splenium ** : AD : MCI : NA * p <.5, ** p <.1. Error bars indicate standard deviation of the mean.
10 Correlations between age, MMSE and WMH severity in each ROI Age Pa Pb Pp Po Cg Cs AD MCI NA MMSE AD MCI NA *.553** *.394* * p <.5, ** p <.1 corrected. Abbreviations: Pa: anterior periventricular region Pb: body of periventricular region Pp: posterior periventricular region Po: occipital periventricular region Cg: genu of corpus callosum Cs: splenium of corpus callosum
11 Conclusion We believe the methods developed here conclusively show the difference of WMH distribution of each cognitive stage. These observations also support the notion of both a common ischemic etiology and Wallerian degeneration as a mechanism of WMH in each cognitive stage. Our study shows that measurements of the extent and distribution of WMH in both corpus callosum and periventricular area are suitable for assessment for NA, MCI and AD.
12 Thanks Student: Ryan Berthold, Chris Davies, Alex Early, Marty Greenia, Evan Lloyd Staff: Lauren Cibattari, Krista Garcia, Oliver Martinez, Mario Ortega, Baljeet Singh, Laura Whiteside, Sky Raptentsetsang
Four Tissue Segmentation in ADNI II
Four Tissue Segmentation in ADNI II Charles DeCarli, MD, Pauline Maillard, PhD, Evan Fletcher, PhD Department of Neurology and Center for Neuroscience, University of California at Davis Summary Table of
Extent and Distribution of White Matter Hyperintensities. in Normal Aging, MCI and AD
Yoshita 1 Extent and Distribution of White Matter Hyperintensities in Normal Aging, MCI and AD NEUROLOGY/2006/147934 M. Yoshita, MD, PhD; E. Fletcher, PhD; D. Harvey, PhD; M. Ortega, BS; O. Martinez, BS;
Extent and distribution of white matter hyperintensities in normal aging, MCI, and AD
Extent and distribution of white matter hyperintensities in normal aging, MCI, and AD M. Yoshita, MD, PhD; E. Fletcher, PhD; D. Harvey, PhD; M. Ortega, BS; O. Martinez, BS; D.M. Mungas, PhD; B.R. Reed,
Diffusion Tensor Imaging in Psychiatry
2003 KHBM DTI in Psychiatry Diffusion Tensor Imaging in Psychiatry KHBM 2003. 11. 21. 서울대학교 의과대학 정신과학교실 권준수 Neuropsychiatric conditions DTI has been studied in Alzheimer s disease Schizophrenia Alcoholism
Summary of findings from the previous meta-analyses of DTI studies in MDD patients. SDM (39) 221 Left superior longitudinal
Supplemental Data Table S1 Summary of findings from the previous meta-analyses of DTI studies in MDD patients Study Analysis Method Included studies, n MDD (medicated) HC Results (MDDHC)
Paul-Chen Hsieh, Ming-Tsung Tseng, Chi-Chao Chao, Yea-Huey Lin Wen-Yih I. Tseng, Kuan-Hong Liu, Ming-Chang Chiang, Sung-Tsang Hsieh
IMAGING SIGNATURES OF ALTERED BRAIN RESPONSES IN SMALL-FIBER NEUROPATHY: REDUCED FUNCTIONAL CONNECTIVITY OF THE LIMBIC SYSTEM AFTER PERIPHERAL NERVE DEGENERATION Paul-Chen Hsieh, Ming-Tsung Tseng, Chi-Chao
The association of children s mathematic abilities with both adults cognitive abilities
Supplemental material for The association of children s mathematic abilities with both adults cognitive abilities and intrinsic fronto-parietal networks is altered in preterm born individuals by Bäuml,
Early Diagnosis of Alzheimer s Disease and MCI via Imaging and Pattern Analysis Methods. Christos Davatzikos, Ph.D.
Early Diagnosis of Alzheimer s Disease and MCI via Imaging and Pattern Analysis Methods Christos Davatzikos, Ph.D. Director, Section of Biomedical Image Analysis Professor of Radiology http://www.rad.upenn.edu/sbia
How to read the report
Dear Client, This is your second opinion report. How to read the report 1. Always consult your findings with your doctor. 2. Please bear in mind that the report is based only on the information you provide
White matter hyperintensities correlate with neuropsychiatric manifestations of Alzheimer s disease and frontotemporal lobar degeneration
White matter hyperintensities correlate with neuropsychiatric manifestations of Alzheimer s disease and frontotemporal lobar degeneration Annual Scientific Meeting Canadian Geriatric Society Philippe Desmarais,
Estimation of Statistical Power in a Multicentre MRI study.
Estimation of Statistical Power in a Multicentre MRI study. PhD Student,Centre for Neurosciences Ninewells Hospital and Medical School University of Dundee. IPEM Conference Experiences and Optimisation
Pediatric MS MRI Study Methodology
General Pediatric MS MRI Study Methodology SCAN PREPARATION axial T2-weighted scans and/or axial FLAIR scans were obtained for all subjects when available, both T2 and FLAIR scans were scored. In order
Cover Page. The handle holds various files of this Leiden University dissertation.
Cover Page The handle http://hdl.handle.net/1887/35124 holds various files of this Leiden University dissertation. Author: Wokke, Beatrijs Henriette Aleid Title: Muscle MRI in Duchenne and Becker muscular
Periventricular T2-hyperintense lesions: does the number matter in CIS?
Periventricular T2-hyperintense lesions: does the number matter in CIS? Dott.ssa Caterina Lapucci Department of Neuroscience, Rehabilitation, Ophthalmology. Genetics, Maternal and Child Health (DINOGMI)
ORIGINAL CONTRIBUTION. Longitudinal Changes in White Matter Disease and Cognition in the First Year of the Alzheimer Disease Neuroimaging Initiative
ORIGINAL CONTRIBUTION Longitudinal Changes in White Matter Disease and Cognition in the First Year of the Alzheimer Disease Neuroimaging Initiative Owen Carmichael, PhD; Christopher Schwarz; David Drucker;
Supplementary Information
Supplementary Information The neural correlates of subjective value during intertemporal choice Joseph W. Kable and Paul W. Glimcher a 10 0 b 10 0 10 1 10 1 Discount rate k 10 2 Discount rate k 10 2 10
Neuropsychiatric Manifestations in Vascular Cognitive Impairment Patients with and without Dementia
86 Neuropsychiatric Manifestations in Vascular Cognitive Impairment Patients with and without Dementia Pai-Yi Chiu 1,3, Chung-Hsiang Liu 2, and Chon-Haw Tsai 2 Abstract- Background: Neuropsychiatric profile
Basic Steps in Planning Research. Dr. P.J. Brink and Dr. M.J. Wood
Basic Steps in Planning Research Dr. P.J. Brink and Dr. M.J. Wood Research Levels Level 1: There is little or no literature available on the topic or on the population. The purpose is to describe what
An integrated natural disease progression model of nine cognitive and biomarker endpoints in patients with Alzheimer s Disease
An integrated natural disease progression model of nine cognitive and biomarker endpoints in patients with Alzheimer s Disease Angelica Quartino 1* Dan Polhamus 2*, James Rogers 2, Jin Jin 1 212, Genentech
Dr Lucy Garvey. Imperial College Healthcare NHS Trust, London. 18 th Annual Conference of the British HIV Association (BHIVA)
18 th Annual Conference of the British HIV Association (BHIVA) Dr Lucy Garvey Imperial College Healthcare NHS Trust, London 18-20 April 2012, The International Convention Centre, Birmingham Microglial
isc ove ring i Statistics sing SPSS
isc ove ring i Statistics sing SPSS S E C O N D! E D I T I O N (and sex, drugs and rock V roll) A N D Y F I E L D Publications London o Thousand Oaks New Delhi CONTENTS Preface How To Use This Book Acknowledgements
Brain Imaging studies in substance abuse. Jody Tanabe, MD University of Colorado Denver
Brain Imaging studies in substance abuse Jody Tanabe, MD University of Colorado Denver NRSC January 28, 2010 Costs: Health, Crime, Productivity Costs in billions of dollars (2002) $400 $350 $400B legal
NIH VCID Biomarkers Consortium focused on the large unmet need for clinical trial ready VCID biomarkers with high potential for positive impact in
NIH VCID Biomarkers Consortium focused on the large unmet need for clinical trial ready VCID biomarkers with high potential for positive impact in public health Steve Greenberg*, MD, PhD, MGH (Coordinating
Supplementary Material. Functional connectivity in multiple cortical networks is associated with performance. across cognitive domains in older adults
Supplementary Material Functional connectivity in multiple cortical networks is associated with performance across cognitive domains in older adults Emily E. Shaw 1,2, Aaron P. Schultz 1,2,3, Reisa A.
Supplementary Online Content
Supplementary Online Content Voineskos AN, Foussias G, Lerch J, et al. Neuroimaging evidence for the deficit subtype of schizophrenia. JAMA Psychiatry. Published online March 6, 2013. doi:10.1001/jamapsychiatry.2013.786.
Detection of Mild Cognitive Impairment using Image Differences and Clinical Features
Detection of Mild Cognitive Impairment using Image Differences and Clinical Features L I N L I S C H O O L O F C O M P U T I N G C L E M S O N U N I V E R S I T Y Copyright notice Many of the images in
Choosing the Correct Statistical Test
Choosing the Correct Statistical Test T racie O. Afifi, PhD Departments of Community Health Sciences & Psychiatry University of Manitoba Department of Community Health Sciences COLLEGE OF MEDICINE, FACULTY
Diffusion Tensor Imaging in Dementia. Howard Rosen UCSF Department of Neurology Memory and Aging Center
Diffusion Tensor Imaging in Dementia Howard Rosen UCSF Department of Neurology Memory and Aging Center www.memory.ucsf.edu Overview Examples of DTI findings in Alzheimer s disease And other dementias Explore
Equating UDS Neuropsychological Tests: 3.0>2.0, 3.0=2.0, 3.0<2.0? Dan Mungas, Ph.D. University of California, Davis
Equating UDS Neuropsychological Tests: 3.0>2.0, 3.0=2.0, 3.0
Post Stroke Brain Plasticity
Post Stroke Brain Plasticity François CHOLLET MD, PhD Neurology Department: Stroke Unit Toulouse University Hospital (CHU) Neurosciences Institute of Toulouse CNRS, INSERM, University, CHU Versailles le
Visual Rating Scale Reference Material. Lorna Harper Dementia Research Centre University College London
Visual Rating Scale Reference Material Lorna Harper Dementia Research Centre University College London Background The reference materials included in this document were compiled and used in relation to
HIV Neurology Persistence of Cognitive Impairment Despite cart
HIV Neurology Persistence of Cognitive Impairment Despite cart Victor Valcour MD PhD Professor of Medicine Memory and Aging Center, Dept. of Neurology University of California San Francisco, USA 8 th International
Nature Neuroscience: doi: /nn Supplementary Figure 1
Supplementary Figure 1 Quantification of myelin fragments in the aging brain (a) Electron microscopy on corpus callosum is shown for a 18-month-old wild type mice. Myelin fragments (arrows) were detected
Structural lesion analysis: applications
Structural lesion analysis: applications Dagmar Timmann Department of Neurology University of Duisburg-Essen, Germany Human cerebellar lesion conditions 1. Focal cerebellar lesions a. Stroke Pro s: - acute
Cerebral amyloid angiopathy (CAA) is defined by the
White Matter Alterations in Cerebral Amyloid Angiopathy Measured by Diffusion Tensor Imaging David H. Salat, PhD; Eric E. Smith, MD, MPH, FRCPC; David S. Tuch, PhD; Thomas Benner, PhD; Vasanth Pappu, BS;
Supplemental Information. Triangulating the Neural, Psychological, and Economic Bases of Guilt Aversion
Neuron, Volume 70 Supplemental Information Triangulating the Neural, Psychological, and Economic Bases of Guilt Aversion Luke J. Chang, Alec Smith, Martin Dufwenberg, and Alan G. Sanfey Supplemental Information
Min-Chien Tu 1,2, Wen-Hui Huang 1, Yen-Hsuan Hsu 3, Chung-Ping Lo 2,4, Jie Fu Deng 1 and Ching-Feng Huang 1,2*
Tu et al. BMC Neurology (2017) 17:144 DOI 10.1186/s12883-017-0911-5 RESEARCH ARTICLE Open Access Comparison of neuropsychiatric symptoms and diffusion tensor imaging correlates among patients with subcortical
PRESERVE: How intensively should we treat blood pressure in established cerebral small vessel disease? Guide to assessing MRI scans
PRESERVE: How intensively should we treat blood pressure in established cerebral small vessel disease? Guide to assessing MRI scans Inclusion Criteria Clinical syndrome Patients must have clinical evidence
Basic Biostatistics. Chapter 1. Content
Chapter 1 Basic Biostatistics Jamalludin Ab Rahman MD MPH Department of Community Medicine Kulliyyah of Medicine Content 2 Basic premises variables, level of measurements, probability distribution Descriptive
Supplementary Materials Are taboo words simply more arousing?
Supplementary Materials Are taboo words simply more arousing? Our study was not designed to compare potential differences on memory other than arousal between negative and taboo words. Thus, our data cannot
Standing strong in the roaring 40s ANZFPS November HOBART. Credit: Tourism Tasmania and Garry Moore
Standing strong in the roaring 40s ANZFPS November 18-20 2018 HOBART Credit: Tourism Tasmania and Garry Moore Thinking on your feet the interplay between cognition, gait and falls Dr Michele Callisaya
Department of Radiology and Research Institute of Radiology, University of Ulsan College of Medicine, Asan Medical Center 2
www.ksmrm.org JKSMRM 16(2) : 115-123, 2012 Print ISSN 1226-9751 Original Article Evaluation of White Matter Abnormality in Mild Alzheimer Disease and Mild Cognitive Impairment Using Diffusion Tensor Imaging:
Cognitive impairment with and without depression history: an analysis of white matter microstructure
Research Paper Cognitive impairment with and without depression history: an analysis of white matter microstructure Shantel L. Duffy, MDR (Hons); Matt Paradise, FRANZCP; Ian B. Hickie, FRANZCP; Simon J.G.
ORIGINAL CONTRIBUTION. Progression of Mild Cognitive Impairment to Dementia in Clinic- vs Community-Based Cohorts. used to describe the transition
ORIGINAL CONTRIBUTION Progression of Mild Cognitive Impairment to Dementia in Clinic- vs Community-Based Cohorts Sarah Tomaszewski Farias, PhD; Dan Mungas, PhD; Bruce R. Reed, PhD; Danielle Harvey, PhD;
Meaning-based guidance of attention in scenes as revealed by meaning maps
SUPPLEMENTARY INFORMATION Letters DOI: 1.138/s41562-17-28- In the format provided by the authors and unedited. -based guidance of attention in scenes as revealed by meaning maps John M. Henderson 1,2 *
M2 microglia/ macrophages drive oligodendrocyte differentiation during CNS remyelination
Supplemental Information Title: M2 microglia/ macrophages drive oligodendrocyte differentiation during CNS remyelination Authors: Veronique E. Miron, Amanda Boyd, Jing-Wei Zhao, Tracy J. Yuen, Julia M.
Clinical Task Force Update
Clinical Task Force Update John C. Morris, MD Friedman Distinguished Professor of Neurology CTF Report Crosswalk Study Report: Clinical Core Meeting LP Survey: Clinical Core Meeting CTF Progress and Future
Magnetic resonance imaging (MR!) provides
0 Wallerian Degeneration of the Pyramidal Tract in Capsular Infarction Studied by Magnetic Resonance Imaging Jesiis Pujol, MD, Josep L. Marti-Vilalta, MD, Carme Junqu6, PhD, Pere Vendrell, PhD, Juan Fernandez,
Structural MRI in Frontotemporal Dementia: Comparisons between Hippocampal Volumetry, Tensor- Based Morphometry and Voxel-Based Morphometry
: Comparisons between Hippocampal Volumetry, Tensor- Based Morphometry and Voxel-Based Morphometry Miguel Ángel Muñoz-Ruiz 1,Päivi Hartikainen 1,2, Juha Koikkalainen 3, Robin Wolz 4, Valtteri Julkunen
Ganglion cell analysis by optical coherence tomography (OCT) Jonathan A. Micieli, MD Valérie Biousse, MD
Ganglion cell analysis by optical coherence tomography (OCT) Jonathan A. Micieli, MD Valérie Biousse, MD Figure 1. Normal OCT of the macula (cross section through the line indicated on the fundus photo)
Attenuation value in HU From -500 To HU From -10 To HU From 60 To 90 HU. From 200 HU and above
Brain Imaging Common CT attenuation values Structure Air Fat Water Brain tissue Recent hematoma Calcifications Bone Brain edema and infarction Normal liver parenchyma Attenuation value in HU From -500
AAP ZIKA ECHO (EXTENSION FOR COMMUNITY HEALTHCARE OUTCOMES)
AAP ZIKA ECHO (EXTENSION FOR COMMUNITY HEALTHCARE OUTCOMES) HOUSEKEEPING ITEMS For educational and quality improvement purposes, this ECHO session will be recorded Project ECHO collects participation data
Power-Based Connectivity. JL Sanguinetti
Power-Based Connectivity JL Sanguinetti Power-based connectivity Correlating time-frequency power between two electrodes across time or over trials Gives you flexibility for analysis: Test specific hypotheses
Enhancement of Cranial US: Utility of Supplementary Acoustic Windows and Doppler Harriet J. Paltiel, MD
Enhancement of Cranial US: Utility of Supplementary Acoustic Windows and Doppler Harriet J. Paltiel, MD Boston Children s Hospital Harvard Medical School None Disclosures Conventional US Anterior fontanelle
Atherosclerosis Risk in Communities Study. NCS Stages 2/3. DERIVED VARIABLE DICTIONARY DERIVE_NCS51 SAS DATASET VERSION 51 October 2016
Atherosclerosis Risk in Communities Study NCS Stages 2/3 DERIVED VARIABLE DICTIONARY DERIVE_NCS51 SAS DATASET VERSION 51 October 2016 Prepared by the Collaborative Studies Coordinating Center ARIC NCS
Behavioral and psychological symptoms of dementia characteristic of mild Alzheimer patients
Blackwell Science, LtdOxford, UKPCNPsychiatry and Clinical Neurosciences1323-13162005 Blackwell Publishing Pty Ltd593274279Original ArticleDementia and mild AlzheimersJ. Shimabukuro et al. Psychiatry and
CADASIL: structural MR imaging changes and apolipoprotein E genotype S E V E N
CADASIL: structural MR imaging changes and apolipoprotein E genotype S E V E N CADASIL: structural MR imaging changes and apolipoprotein E genotype R. van den Boom S.A.J. Lesnik Oberstein A.A. van den
Diagnostic improvement from average image in acute ischemic stroke
Diagnostic improvement from average image in acute ischemic stroke N. Magne (1), E.Tollard (1), O. Ozkul- Wermester (2), V. Macaigne (1), J.-N. Dacher (1), E. Gerardin (1) (1) Department of Radiology,
CLINICAL SCIENCE. Rosalvo Zosimo Bispo Júnior, a Cezar Teruyuki Kawano, b Alexandre Vieira Guedes b
CLINICS 2008;63(1):3-8 CLINICAL SCIENCE CHRONIC MULTIPLE KNEE LIGAMENT INJURIES: EPIDEMIOLOGICAL ANALYSIS OF MORE THAN ONE HUNDRED CASES Rosalvo Zosimo Bispo Júnior, a Cezar Teruyuki Kawano, b Alexandre
Research Article Corticospinal Tract Change during Motor Recovery in Patients with Medulla Infarct: A Diffusion Tensor Imaging Study
BioMed Research International, Article ID 524096, 5 pages http://dx.doi.org/10.1155/2014/524096 Research Article Corticospinal Tract Change during Motor Recovery in Patients with Medulla Infarct: A Diffusion
Non-arteritic anterior ischemic optic neuropathy (NAION) with segmental optic disc edema. Jonathan A. Micieli, MD Valérie Biousse, MD
Non-arteritic anterior ischemic optic neuropathy (NAION) with segmental optic disc edema Jonathan A. Micieli, MD Valérie Biousse, MD A 75 year old white woman lost vision in the inferior part of her visual
Early Diffusion MR Imaging Findings and Short-Term Outcome in Comatose Patients with Hypoglycemia
ORIGINAL RESEARCH K. Johkura Y. Nakae Y. Kudo T.N. Yoshida Y. Kuroiwa Early Diffusion MR Imaging Findings and Short-Term Outcome in Comatose Patients with Hypoglycemia BACKGROUND AND PURPOSE: The relationship
One way Analysis of Variance (ANOVA)
One way Analysis of Variance (ANOVA) Esra Akdeniz March 22nd, 2016 Introduction Test hypothesis concerning one population mean. Test hypothesis concerning two population means What if we want to compare
EXPEDITION3: A Phase 3 Trial of Solanezumab in Mild Dementia due to Alzheimer s Disease
EXPEDITION3: A Phase 3 Trial of in Mild Dementia due to Alzheimer s Disease Lawrence S. Honig, MD, PhD On behalf of the EXPEDITION3 Study Team Disclosure Statement I will discuss investigational use only.
Online supplement data :
Online supplement data : ROI ROI name MNI coord (mm) HC>SZ HC>S ZR HC>P BP HC>P BPR Heritabil ity h^2 Heritability p-value MCP Middle cerebellar peduncle 0-41 -44 2.05 2.12 1.63 0.69 0.38 0.004473 PCT
Supplementary Results: Age Differences in Participants Matched on Performance
Supplementary Results: Age Differences in Participants Matched on Performance 1 We selected 14 participants for each age group which exhibited comparable behavioral performance (ps >.41; Hit rates (M ±
International Journal of Scientific & Engineering Research Volume 9, Issue 1, January ISSN
International Journal of Scientific & Engineering Research Volume 9, Issue 1, January-2018 781 Prevalence of depression among diabetic patients and the factors affecting it Fahad Mousa Wasili,Abrar Yousef
Effects Of Virtual Reality Training on Balance Function In Older Adults with Cognitive Impairment. Yi-Cheng Cathy Lin M.S., P.T.
Effects Of Virtual Reality Training on Balance Function In Older Adults with Cognitive Impairment Yi-Cheng Cathy Lin M.S., P.T. Introduction 2 Cognitive impairment includes the memory dysfunction, behavioral
Neuroanatomy lecture (1)
Neuroanatomy lecture (1) Introduction: Neuroanatomy has two parts: the central and peripheral nervous system. The central nervous system is composed of brain and spinal cord. The brain has the following
Papers recently published using NACC data. Lilah Besser, PhD, MSPH
Papers recently published using NACC data Lilah Besser, PhD, MSPH Example publications, 2016-2017 NACC data used Author Year UDS Kielb et al 2017 NP + UDS Sposato et al 2017 MRI + UDS Lange et al 2016
Quantification of intracellular payload release from
Quantification of intracellular payload release from polymersome nanoparticles Edoardo Scarpa 1,2, Joanne L. Bailey 2, Agnieszka A. Janeczek 1,2, Patrick S. Stumpf 1,2, Alexander H. Johnston 2, Richard
Diffusion-Weighted and Conventional MR Imaging Findings of Neuroaxonal Dystrophy
AJNR Am J Neuroradiol 25:1269 1273, August 2004 Diffusion-Weighted and Conventional MR Imaging Findings of Neuroaxonal Dystrophy R. Nuri Sener BACKGROUND AND PURPOSE: Neuroaxonal dystrophy is a rare progressive
ORIGINAL CONTRIBUTION. Risk Factors for Mild Cognitive Impairment. study the Cardiovascular Health Study Cognition Study.
Risk Factors for Mild Cognitive Impairment in the Cardiovascular Health Study Cognition Study Part 2 ORIGINAL CONTRIBUTION Oscar L. Lopez, MD; William J. Jagust; Corinne Dulberg, PhD; James T. Becker,
2 nd Annual Internatioanl Conference on Nursing, 2-5 May 2016, Athens Greece
SELF ESTEEM AND SOCIAL VIEW ANXIETY IN COSMETIC SURGERY PATIENT Hayriye ÜNLÜ Assoc. Prof. Nevin DOĞAN Lecturer Baskent University Health Sciences Faculty, Department Of Nursing 2 nd Annual Internatioanl
Visualization strategies for major white matter tracts identified by diffusion tensor imaging for intraoperative use
International Congress Series 1281 (2005) 793 797 www.ics-elsevier.com Visualization strategies for major white matter tracts identified by diffusion tensor imaging for intraoperative use Ch. Nimsky a,b,
High spatial resolution reveals excellent detail in pediatric neuro imaging
Publication for the Philips MRI Community Issue 46 2012/2 High spatial resolution reveals excellent detail in pediatric neuro imaging Achieva 3.0T with 32-channel SENSE Head coil has become the system
CNS Imaging. Dr Amir Monir, MD. Lecturer of radiodiagnosis.
CNS Imaging Dr Amir Monir, MD Lecturer of radiodiagnosis www.dramir.net Types of radiological examinations you know Plain X ray X ray with contrast GIT : barium (swallow, meal, follow through, enema) ERCP
A pictorial review of neurological complications of systemic lupus erythematosus and antiphospholipid syndrome
A pictorial review of neurological complications of systemic lupus erythematosus and antiphospholipid syndrome Poster No.: C-2780 Congress: ECR 2010 Type: Educational Exhibit Topic: Neuro Authors: E. Tavernaraki,
PRETERM BIRTH RESULTS IN ALTERATIONS IN NEURAL CONNECTIVITY AT AGE 16 YEARS
Yale University EliScholar A Digital Platform for Scholarly Publishing at Yale Yale Medicine Thesis Digital Library School of Medicine 8-17-2010 PRETERM BIRTH RESULTS IN ALTERATIONS IN NEURAL CONNECTIVITY
Valutazione dei disturbi neurocognitivi e invecchiamento: non solo HAND. Workshop Nazionale CISAI Lecco 20 Marzo 2015
Valutazione dei disturbi neurocognitivi e invecchiamento: non solo HAND Workshop Nazionale CISAI Lecco 20 Marzo 2015 Paola Cinque Dipartimento di Malattie Infettive Istituto Scientifico San Raffaele, Milano
Across the Cognitive Impairment Continuum Increasing Patient Dependence is Associated with an Increase in Caregiver Burden
Across the Cognitive Impairment Continuum Increasing Patient Dependence is Associated with an Increase in Caregiver Burden Loretto Lacey Janssen Alzheimer s Immunotherapy Dublin, Ireland Alzheimer's Europe
ARIC V5 / NCS Code Book III, S.5. Section 5: Derived Variable File
Chapter III. Derived Files Derived Variable Dataset (DERIVE_NCS51) ARIC V5 / NCS Code Book III, S.5 Page 1 of 16 Derived Variable Dataset: FORM CODE=DERIVE_NCS51 VERSION=1.0 Instructions: Derived variables
Assessing Brain Volumes Using MorphoBox Prototype
MAGNETOM Flash (68) 2/207 33 Assessing Brain Volumes Using MorphoBox Prototype Alexis Roche,2,3 ; Bénédicte Maréchal,2,3 ; Tobias Kober,2,3 ; Gunnar Krueger 4 ; Patric Hagmann ; Philippe Maeder ; Reto
Theory of mind skills are related to gray matter volume in the ventromedial prefrontal cortex in schizophrenia
Theory of mind skills are related to gray matter volume in the ventromedial prefrontal cortex in schizophrenia Supplemental Information Table of Contents 2 Behavioral Data 2 Table S1. Participant demographics
Using a Likert-type Scale DR. MIKE MARRAPODI
Using a Likert-type Scale DR. MIKE MARRAPODI Topics Definition/Description Types of Scales Data Collection with Likert-type scales Analyzing Likert-type Scales Definition/Description A Likert-type Scale
COUNTY PROFILE: Laurens County, Georgia
COUNTY PROFILE: Laurens County, Georgia US COUNTY PERFORMANCE The Institute for Health Metrics and Evaluation (IHME) at the University of Washington analyzed the performance of all 3,142 US counties or
Comparative Study of Different Digoxin Treatment Regimens in Egyptian Hospitals. For Partial Fulfillment of Master Degree in Pharmaceutical Sciences
Comparative Study of Different Digoxin Treatment Regimens in Egyptian Hospitals A Thesis presented by Sahar Atef Azmy Al Shabasy, BSc Teaching Assistant, Clinical Pharmacy Department, Faculty of Pharmacy,
Delayed Encephalopathy of Acute Carbon Monoxide Intoxication: Diffusivity of Cerebral White Matter Lesions
AJNR Am J Neuroradiol 24:1592 1597, September 2003 Delayed Encephalopathy of Acute Carbon Monoxide Intoxication: Diffusivity of Cerebral White Matter Lesions Ji-hoon Kim, Kee-Hyun Chang, In Chan Song,
Table of Contents. Plots. Essential Statistics for Nursing Research 1/12/2017
Essential Statistics for Nursing Research Kristen Carlin, MPH Seattle Nursing Research Workshop January 30, 2017 Table of Contents Plots Descriptive statistics Sample size/power Correlations Hypothesis
Clinical Applications of fmri
Clinical Applications of fmri Benjamin M. Hampstead, Ph.D., ABPP/CN Associate Professor Department of Psychiatry University of Michigan VA Ann Arbor Healthcare System No Disclosures or Conflicts Hampstead
Structural And Functional Integration: Why all imaging requires you to be a structural imager. David H. Salat
Structural And Functional Integration: Why all imaging requires you to be a structural imager David H. Salat salat@nmr.mgh.harvard.edu Salat:StructFunct:HST.583:2015 Structural Information is Critical
A semantic verbal fluency test for English- and Spanish-speaking older Mexican-Americans
Archives of Clinical Neuropsychology 20 (2005) 199 208 A semantic verbal fluency test for English- and Spanish-speaking older Mexican-Americans Hector M. González a,, Dan Mungas b, Mary N. Haan a a University
UNIVERSITY OF CALGARY. A New Method for Assessing Tissue Alignment using Clinical MRI in Multiple Sclerosis. Shrushrita Sharma A THESIS
UNIVERSITY OF CALGARY A New Method for Assessing Tissue Alignment using Clinical MRI in Multiple Sclerosis by Shrushrita Sharma A THESIS SUBMITTED TO THE FACULTY OF GRADUATE STUDIES IN PARTIAL FULFILMENT
September 26 28, 2013 Westin Tampa Harbour Island. Co-sponsored by
September 26 28, 2013 Westin Tampa Harbour Island Co-sponsored by From Brains at Risk to Cognitive Dysfunction: The Role of Vascular Pathology Ralph Sacco, MD, MS, FAHA, FAAN Miller School of Medicine
Supplementary Online Content
Supplementary Online Content Redlich R, Opel N, Grotegerd D, et al. Prediction of individual response to electroconvulsive therapy via machine learning on structural magnetic resonance imaging data. JAMA
Quantitative Neuroimaging- Gray and white matter Alteration in Multiple Sclerosis. Lior Or-Bach Instructors: Prof. Anat Achiron Dr.
Quantitative Neuroimaging- Gray and white matter Alteration in Multiple Sclerosis Lior Or-Bach Instructors: Prof. Anat Achiron Dr. Shmulik Miron INTRODUCTION Multiple Sclerosis general background Gray
A. One to three months of age. Anterior Lens (Mean ± SEM) Posterior Lens (Mean ± SEM) Mid Lens (Mean ± SEM) Cornea (Mean ± SEM) Genotype
Supplementary Table 1. Location of lens opacification in Aldh1a1(-/-), Aldh3a1(-/-) single and Aldh1a1(-/-)/Aldh3a1(-/-) double knockout mice (DKO) at different ages. A. One to three months of age Genotype
Machine Learning Algorithms for Neuroimaging-based Clinical Trials in Preclinical Alzheimer s Disease
Machine Learning Algorithms for Neuroimaging-based Clinical Trials in Preclinical Alzheimer s Disease Vamsi K. Ithapu Wisconsin Alzheimer s Disease Research Center University of Wisconsin-Madison April
The Future for Diffusion Tensor Imaging in Neuropsychiatry
WINDOWS TO THE BRAIN Robin A. Hurley, M.D., L. Anne Hayman, M.D., Katherine H. Taber, Ph.D. Section Editors The Future for Diffusion Tensor Imaging in Neuropsychiatry Katherine H. Taber, Ph.D., Carlo Pierpaoli,
Demyelinating Diseases of the Brain
Department of Radiology University of California San Diego Demyelinating Diseases of the Brain John R. Hesselink, M.D. T1-Weighted Images Normal White Matter Contents Axons with envelope of myelin Neuroglia