INTERNATIONAL MYELOMA SOCIETY EDUCATIONAL WORKSHOP. October 27-28, 2017 Gaylord National Hotel Washington, D.C. Metro Area

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1 INTERNATIONAL MYELOMA SOCIETY EDUCATIONAL WORKSHOP October 27-28, 2017 Gaylord National Hotel Washington, D.C. Metro Area The International Myeloma Society (IMS) is a professional, scientific and medical society established to bring together clinical and experimental scientists involved in the study of myeloma. The IMS accomplishes its mission by providing educational forums in the form of conferences, symposia, and workshops conducted around the globe. The goal for the Educational Workshop is to share with local hematologists the state of the art on diagnosis, monitoring and treatment of Plasma Cell malignancies paying special attention to the current practice in the local countries and the opportunities for improvement. Our purpose is also to offer the opportunity for social interaction in order to establish potential collaborations with the invited speakers including the possibility of visiting the institutions or establishing fellowship programs. The program will include lectures plus roundtable discussions around the most hot and controversial topics. The format of the roundtable will include the counterpoint opinion of the invited speakers with the local hematologists based on both challenging questions and clinical cases. Program Chairs: Noopur Raje, MD Director, Center for Multiple Myeloma Massachusetts General Hospital Cancer Center Boston, Massachusetts Professor of Medicine, Harvard Medical School Robert Orlowski, MD, PhD Chairman, Ad Interim, Director of Myeloma and Professor of Medicine Departments of Lymphoma/Myeloma MD Anderson Cancer Center, Houston, Texas Shaji Kumar, MD Professor of Medicine Mayo Clinic, Rochester, MN Program Committee: Ashraf Badros University of Maryland Medical Center David Vesole Georgetown University

2 Washington, DC PRELIMINARY PROGRAM This activity has been planned and implemented in accordance with the accreditation requirements and policies of the Accreditation Council for Continuing Medical Education (ACCME) through the joint providership of Mayo Clinic College of Medicine and Science and the International Myeloma Society. Mayo Clinic College of Medicine and Science is accredited by the ACCME to provide continuing medical education for physicians. The Mayo Clinic College of Medicine and Science designates this live activity for a maximum of AMA PRA Category 1 Credit(s). Physicians should claim only the credit commensurate with the extent of their participation in the activity. Friday, October 27, :15-08:30 Welcome and introduction 08:30-9:00 Multiple Myeloma: The past, present and future Robert A Kyle 9:00-9:30 Genomics to predict disease outcomes: are we there yet? Herve Avet-Loiseau 9:30-10:00 What are the optimal Imaging Techniques in MM, MRI, CT-scan and PET? Noopur Raje 10:00-10:30 Coffee 10:30-11:00 Implementing the new diagnostic criteria in daily practice and appropriate tests for follow up and treatment decisions Ajai Chari 11:00-11:30 Minimal residual Disease. How and when to do it? Nikhil Munshi 11:30-12:00 Roundtable: How to do a correct diagnosis and follow-up: Controversial cases with emphasis on local practice Moderator: Nikhil Munshi Discussants: Hervé Avet-Loiseau, Noopur Raje, Ajai Chari, Ashraf Badros, Sundar Jagannath 12:00-13:00 Lunch

3 Friday, October 27, 2017 Continued 13:00-13:30 Management of Renal Disease in monoclonal gammopathies Nelson Leung 13:30-15:30 How I treat newly diagnosed transplant eligible MM patients? (20 minutes for each talk and four cases 10 minutes each) 15:30-16:00 Coffee The best induction and risk adapted approaches for initial therapy in myeloma Robert Orlowski Role of autologous stem cell transplant Sundar Jagannath When should we use consolidation and maintenance? Ravi Vij Allogeneic stem cell transplant in myeloma: is there still a role? David Vesole Roundtable: Optimizing the use of stem cell transplant in myeloma Controversial cases presented by local physicians with emphasis on local practice Moderator: Sundar Jagannath Discussants: Robert Orlowski, Sundar Jagannath, David Vesole, Noopur Raje, Faith Davies 16:00-16:30 MGUS & Smoldering Myeloma. How to predict outcome & To treat or not to treat Ashraf Badros 16:30-17:00 Treatment of Disease Complications Luciano Costa

4 Saturday, October 28, :00-8:30 Future targets and therapy in myeloma? Kenneth Anderson 8:30-10:00 How I treat newly diagnosed elderly patients? (20 minutes for each talk and three cases 10 minutes each) 10:00-10:30 Coffee Break Induction and maintenance therapy in Elderly Shaji Kumar How do we utilize Frailty score in elderly? Natalie Callander Roundtable: Controversial elderly cases with emphasis on US practice Moderator: Shaji Kumar Discussants: Faith Davies, Sagar Lonial, Nikhil Munshi, Donna Reece, Natalie Callander 10:30 11:30 How do I treat? Waldenström Macroglobulinemia Steve Treon Amyloidosis: Under-diagnosed disorder Shayna Sarosiek 11:30-13:30 How to make the right choices in the relapsed patient? 13:30 Lunch How do we manage 1 st relapse Sagar Lonial Approaches for refractory myeloma Jacob Laubach Roundtable: Controversial cases with emphasis on US practice Moderator: Sagar Lonial Discussants: Paul Richardson, Sundar Jagannath; Robert Orlowski, Phil McCarthy, Faith Davies

5 THANK YOU TO OUR SPONSORS Platinum This activity is supported by an educational grant from Celgene Corporation. Gold Silver