16 th Annual Indy Hematology Review

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1 16 th Annual Indy Hematology Review Saturday, March 9, 2019 JW Marriott Indianapolis 10 S. West Street Indianapolis, IN Presented by: Organized by: Indy Hematology Education, Inc. This Symposium is approved for 8.5 AMA PRA Category 1 Credit(s) TM, 8.0 CNE contact hours, and 8.0 CPE contact hours by the Purdue University College of Pharmacy.

2 A full day of presentations by today s leaders in Hematology and Hematologic Malignancies Gain comprehensive clinical content that will immediately impact your practice. This full-day symposium features a series of didactic lectures presented by the nation s top hematology experts from the Dana-Farber Cancer Institute, MD Anderson Cancer Center, Johns Hopkins School of Medicine, Lombardi Comprehensive Cancer Center, Mayo Clinic, and more! The Indy Hematology Review brings together over 300 hematologists, oncologists, radiologists, physician assistants, oncology RN s, nurse practitioners, pharmacists, medical students, and other allied health professionals. Stay current with a concise summary of the critical data presented at the American Society of Hematology (ASH) annual meeting. Examine significant scientific updates in clinical hematologic research, learn how these updates directly affect the study and practice of hematology, and discover how new research can be translated into new patient care strategies. Dive deeper into new advances and targeted treatments for: Multiple Myeloma Waldenström s Macroglobulinemia Benign and Non-Benign Hematology Indolent Lymphomas and Hodgkin s Lymphoma Acute Lymphoblastic Leukemia Chronic and Acute Myeloid Leukemias Myeloproliferative Neoplasms Myelodysplastic Syndrome Hematopoietic Stem Cell Transplantation Visit the Exhibit Hall Visit the exhibit hall to experience a showcase of the latest technology and research in hematology. The exhibit hall offers an opportunity to learn about a wide range of products and services offered by pharmaceutical companies, medical suppliers, biotechnology companies, healthcare systems, and research-based companies. Stop in for a beverage and snack at the Physicians Lounge as you visit exhibitors.

3 SUPPORTERS & SPONSORSHIPS PLANNING COMMITTEE Ruemu Birhiray, MD (Chair) CEO, Indy Hematology Education, Inc. Partner and Vice President, Hematology Oncology of Indiana, PC Michael C. Wiemann, MD, FACP (Co-Chair) President, Providence Hospital Executive Vice President West Region, St. John Providence Health System Donna Birhiray, OTR, MBA Indy Hematology Education, Inc. Treasurer Thalia Hammond Indy Hematology Education, Inc. The 2019 Indy Hematology Review is supported by: AstraZeneca Bristol-Myers Squibb Immunomedics Incyte Pharmacyclics Jennifer Wheeler-Terry, JD Wabash College Debbie Locklear Meeting Services Unlimited, Inc. President Tina Machina, CMP Meeting Services Unlimited, Inc. Director of Conventions INDY HEMATOLOGY EDUCATION, INC. Indy Hematology Education, Inc. is a 501(c), non-profit corporation, incorporated on February 15, 2010, in the State of Indiana, with the following purposes: (a) Raise awareness and provide education regarding hematology and oncology diseases and disorders (b) To encourage youth to pursue careers in hematology and oncology and BOARD OF DIRECTORS Ruemu E. Birhiray, MD, President and CEO Michael C. Wiemann, MD, FACP, Vice-President Jennifer Terry, JD, Secretary and Director Donna M. Birhiray, OT, MBA, Treasurer and Director Thalia Hammond, Director (c) To connect individuals suffering from or affected by hematology and oncology diseases and disorders to organizations, programs, and service providers.

4 MAIN SYMPOSIUM AGENDA 7:00 AM - 2:30 PM Registration 7:00 AM - 5:00 PM Exhibit displays 7:30 AM Breakfast: Product Theaters 8:30 AM State of the Art: 2019 Emerging Therapies in Hematologic Malignancies Ruemu E. Birhiray, MD Chair CEO, Indy Hematology Education, Inc. Associate Professor of Clinical Medicine, Marian University of Osteopathic Medicine Partner and Vice President, Hematology Oncology of Indiana, PC (Indianapolis, IN) 9:00 AM Multiple Myeloma: Changing and Emerging Treatment Paradigms Kenneth Anderson, MD Kraft Family Professor of Medicine, Harvard Medical School Program Director of the Lebow Institute for Myeloma Therapeutics and Jerome Lipper Multiple Myeloma Center, Dana- Farber Cancer Institute (Boston, MA) 9:30 AM Waldenström s Macroglobulinemia: Beyond the Diagnosis Steven Treon, MD, MA, PhD Associate Professor of Medicine, Harvard Medical School Senior Attending Physician for Medical Oncology at DFCI and Brigham & Women s Hospital Director of the Bing Center for Waldenström s Macroglobulinemia Dana-Farber Cancer Institute (Boston, MA) 10:00 AM Chronic Lymphocytic Leukemia: How to Treat in 2019 Michael Keating, MB, BS Clinical Professor of Medicine, Department of Leukemia Division of Cancer Medicine The University of Texas MD Anderson Cancer Center (Houston, TX) 10:45 AM Indolent Lymphomas and Hodgkin s Lymphoma: Achieving Curability Bruce Cheson, MD, FACP, FAAS, FASCO Deputy Chief of Division of Hematology and Oncology Head of Hematology and Professor of Medicine Lombardi Comprehensive Cancer Center MedStar Georgetown University Hospital (Washington, DC) 11:15 AM Aggressive B and T Cell Lymphomas: Chemotherapy, Antibodies, Immunotherapy John Leonard, MD Attending Physician, New York-Presbyterian Hospital Richard T. Silver Distinguished Professor of Hematology and Medical Oncology Associate Dean of Clinical Research and Interim Chair of Department of Medicine Weill Cornell Medical College (New York, NY) 11:45 AM Not so Benign Hematology: Complementopathies and Aplastic Anemia Robert Brodsky, MD Director of Division of Hematology Johns Hopkins Family Professor of Medicine and Oncology Johns Hopkins University School of Medicine (Baltimore, MD) 12:15 PM Benign Hematology: Cytopenias, Clotting, and Bleeding Craig Kessler, MD Professor of Medicine and Pathology Director of Clinical Coagulation Laboratory in Division of Laboratory Medicine Lombardi Comprehensive Cancer Center MedStar Georgetown University Hospital (Washington, DC) 12:45 PM Q & A 1:00 PM Lunch: Product Theaters 2:00 PM T. HOWARD LEE KEYNOTE LECTURE: Emerging Targeted Therapies for Follicular Lymphomas: A Future Without Chemotherapy Pier Zinzani, MD, PhD Professor of Hematology, Head of Lymphoma Group Institute of Hematology L. e A. Seràgnoli University of Bologna (Bologna, Italy) 3:00 PM Challenging Cases Presentation Michael C. Wiemann, MD Co-Chair President of Providence Hospital Executive Vice President West Region, St. John Providence Health System (Warren, MI) 3:05 PM Chronic Myeloid Leukemia: Targeted Therapy in 2019 Richard Larson, MD Professor of Medicine in Section of Hematology/Oncology, Director of Hematologic Malignancies Clinical Research Program The University of Chicago Comprehensive Cancer Center (Chicago, IL) 3:35 PM Myeloproliferative Neoplasms: Genetic Prognostication and Current Treatment Ayalew Tefferi, MD, PhD Professor of Hematology and Internal Medicine Mayo Clinic (Rochester, MN) 4:05 PM Practical Considerations in the Treatment of Polycythemia Vera and Myelofibrosis Angela Fleischman, MD, PhD Assistant Professor, Department of Medicine Division of Hematology/Oncology University of California, Irvine Health (Irvine, CA) 4:35 PM Break with Q & A 10:30 AM Break with Q & A

5 4:45 PM Acute Lymphoblastic Leukemia: Emerging and Targeted Therapies Hagop Kantarjian, MD Samsung Distinguished University Chair in Cancer Medicine, Associate Vice President for Global Academic Programs, Professor and Department Chair, Department of Leukemia, Division of Cancer Medicine The University of Texas MD Anderson Cancer Center (Houston, TX) 5:15 PM Acute Myeloid Leukemias: Treatment Options in 2019 Martin Tallman, MD Chief of Leukemia Service and Professor of Medicine Memorial Sloan-Kettering Cancer Center Weill Cornell Medical College (New York, NY) 5:45 PM Myelodysplastic Syndrome; How Much Further Do We Have To Travel? Richard Stone, MD Attending Physician, Brigham and Women s Hospital Professor of Medicine, Harvard Medical School Director, Adult Leukemia Program Dana-Farber Cancer Institute (Boston, MA) 6:15 PM Hematopoietic Stem Cell Transplantation: How I Treat and When I Transplant in 2019 Richard Childs, MD, RADM, USPHS Senior Investigator for Laboratory of Transplantation Immunotherapy Clinical Director, National Heart, Lung, and Blood Institute (NHLBI) National Institutes of Health (Bethesda, MD) 6:45 PM Wrap Up and Adjourn 7:00 PM 8:30 PM Challenging Cases in Lymphoproliferative and Plasma Cell Disorders / Interactive Meeting with the Professors / Reception Paul Richardson, MD R.J. Corman Professor of Medicine, Harvard Medical School Clinical Program Leader and Director of Clinical Research of the Jerome Lipper Multiple Myeloma Center, Dana-Farber Cancer Institute (Boston, MA) Sonali Smith, MD Elwood V. Jensen Professor of Medicine Director, Lymphoma Program The University of Chicago (Chicago, IL) NURSING SYMPOSIUM AGENDA 8:30 AM State of the Art: 2019 Emerging Therapies in Hematologic Malignancies Ruemu E. Birhiray, MD Chair 9:00 AM Indolent Lymphomas and Hodgkin s Lymphoma Bruce Cheson, MD, FACP, FAAS, FASCO 10:35 AM Chronic Leukemias Michael Keating, MB, BS 10:55 AM Break with Q & A 11:10 AM Myeloproliferative Neoplasms Ayalew Tefferi, MD, PhD 12:10 PM Emesis and Nutritional Strategies for Hematologic Malignancies 12:30 PM Multiple Myeloma Paul Richardson, MD 12:50 PM Break with Q & A 9:20 AM Benign Hematology and Coagulopathy Craig Kessler, MD 9:40 AM Acute Leukemia and MDS Richard Stone, MD 11:30 AM Recognition and Management of Toxicities of Oral Therapeutics in Hematologic Malignancies Michelle Wright Mast, FNP-BC Nurse Practitioner, Hematology/Oncology St. Vincent Medical Group (Indianapolis, IN) 1:00 PM Lunch: Product Theaters 2:00 PM Adjourn and join General Session for T. Howard Lee Lecture 10:00 AM Break with Q & A 10:15 AM Aggressive Lymphomas Sonali Smith, MD 11:50 AM Management of Long-Term Survivors of Hematologic Malignancies Kristi Orbaugh, RN, MSN RNP, AOCN Adult Nurse Practitioner Community Hospital Oncology Physicians (Indianapolis, IN) Disclosure information, biographies, and slides (where authorized by the presenter) will be available at indyhematologyreview.com

6 REGISTRATION To register online, go to indyhematologyreview.com and click on Register. Early Bird Registration: ends February 15, 2019 Early Bird Physicians $ Early Bird Physicians + CME Fee $ Early Bird Allied Health & Nurses $ Early Bird Allied Health & Nurses + CNE Fee $ Early Bird Nurse Practitioners & Pharmacists $ Early Bird Nurse Practitioners & Pharmacists + CPE Fee $ Industry & Exhibitors $ Standard Registration: after February 15, 2019 Physicians $ Physicians + CME Fee $ Allied Health & Nurses $ Allied Health & Nurses + CNE Fee $ Nurse Practitioners & Pharmacists $ Nurse Practitioners & Pharmacists + CPE Fee $ Industry & Exhibitors $ Student/Fellow Scholarship* (Limited Number) $25.00 Nurse Scholarship* (Limited Number) $25.00 *A limited number of scholarships are available on a first-come, first-served basis. If you are registering clinicians for your office, fill in the attendee s full name and address so the post-event survey and continuing education credits are ed to the attendee. REFUND POLICY Request a registration cancellation refund on or before February 22, 2019, to receive a Full Refund. After February 22, there is NO REFUND. HOTEL RESERVATIONS Make your reservation online at indyhematologyreview.com and click on Hotel/Parking. You may also call the JW Marriott Indianapolis directly at or toll free at Mention Indy Hematology Review for the discounted group rate of $192 plus tax (currently 17%). Access to the block of discounted rooms will close on Friday, February 15, Make your reservation early! PARKING Parking is available at the JW Marriott Indianapolis. 24-hour parking rates are currently: $44.00 on-site parking; $49.00 valet. *Rates are subject to change without notice. Self-parking is also available at the Government Center Washington St. Parking Facility, 401 West Washington Street. First Hour: $15.00; Daily Maximum: $25.00 QUESTIONS? Please contact , Indyhr@conventionmanagers.com.

7 CONTINUING EDUCATION INFORMATION PHYSICIANS LEARNING OBJECTIVES At the completion of this activity, participants should be able to: 1. Discuss new emerging hematology therapies in general and for chronic Myeloid Leukemia, acute Promylelocytic and Myeloid Leukemia, and Myeloproliferative neoplasms. 2. Evaluate molecular diagnosis, targeted therapies, and resistance mechanisms of Waldenström s Macroglobulinemia to assist in disease recognition. 3. Discuss the advancement of immune check point inhibitors within hematologic malignancies and updated treatment paradigms presented at the American Society of Hematology meeting in San Diego, CA in December Recommend new regimens for Hematopoietic Stem Cell transplantation and identification of transplant candidates. 5. Review the advancement in benign hematology research. 6. Review new treatment regimens in follicular lymphoma. CME ACCREDITATION STATEMENT This activity has been planned and implemented in accordance with the accreditation requirements and policies of the Accreditation Council for Continuing Medical Education (ACCME) through the joint providership of Purdue University College of Pharmacy and Indy Hematology Education, Inc. Purdue University is accredited by the ACCME to provide continuing medical education for physicians. DESIGNATION STATEMENT Purdue University College of Pharmacy designates this live activity for a maximum of 8.5 AMA PRA Category 1 Credit(s). Physicians should claim only the credit commensurate with the extent of their participation in the activity. DISCLOSURE STATEMENT All faculty, staff, and reviewers involved in the planning, review, or presentation of continuing education activities provided by Purdue University College of Pharmacy are required to disclose to the audience any relevant commercial financial affiliations related to the content of the presentation or enduring material. Full disclosure of all commercial relationships must be made in writing to the audience prior to the activity. All additional planning committee members, staff, and reviewers of Indy Hematology Education, Inc. and Purdue University College of Pharmacy have no relationships to disclose. NURSES CNE ACCREDITATION STATEMENT Purdue University Continuing Nursing Education is accredited as a provider of continuing nursing education with distinction by the American Nurses Credentialing Center s Commission on Accreditation. This program is approved for 8.0 contact hours. PHARMACISTS CPE ACCREDITATION STATEMENT Purdue University College of Pharmacy is accredited by the Accreditation Council for Pharmacy Education as a provider of continuing pharmacy education. This is a knowledge based, continuing education activity of Purdue University, an equal access/equal opportunity institution. Universal Activity Number (UAN): L01-P This program is approved for 8.0 contact hours (0.8 CEU s). PHARMACY LEARNING OBJECTIVES At the completion of this activity, participants should be able to: 1. Discuss new emerging hematology therapies in general and for chronic Myeloid Leukemia, acute Promylelocytic and Myeloid Leukemia, and Myeloproliferative neoplasms. 2. Evaluate molecular diagnosis, targeted therapies, and resistance mechanisms of Waldenström s Macroglobulinemia to assist in disease recognition. 3. Discuss the advancement of immune check point inhibitors within hematologic malignancies and updated treatment paradigms presented at the American Society of Hematology meeting in San Diego, CA in December Recommend new regimens for Hematopoietic Stem Cell transplantation and identification of transplant candidates. 5. Review the advancement in benign hematology research. 6. Review new treatment regimens in follicular lymphoma. NOTE: While it offers CME credits, this activity is not intended to provide extensive training or certification in the field.

8 Indy Hematology Review C/O Meeting Services Unlimited 135 S. Mitthoeffer Rd. Indianapolis, IN Presented by: 16 th Annual Indy Hematology Review Saturday, March 9, :00 am 8:30 pm JW Marriott Indianapolis 10 S. West Street Indianapolis, IN

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