Acamprosate in Relapse Prevention of Alcoholism
|
|
- Kenneth Blair
- 6 years ago
- Views:
Transcription
1 Acamprosate in Relapse Prevention of Alcoholism
2 Springer Berlin Heidelberg New York Barcelona Budapest Hong Kong London Milan Paris Santa Clara Singapore Tokyo
3 M. Soyka (Ed.) Acamprosate in Relapse Prevention of Alcoholism With 47 Figures and 16 Tables, Springer
4 PD Dr. Michael Soyka Psychiatrische Klinik und Poliklinik der Universitat Miinchen NuBbaumstr Miinchen, Germany ISBN-13 : DOl: / e-isbn-13 : Library of Congress Cataloging-in-Publication Data. Acamprosate in relapse prevention of alcoholism! M.Soyka,ed. p. cm. Includes bibliographical references and index. ISBN-13: (hardcover)!. Alcoholism - Chemotherapy. 2. Acamprosate. 3. Alcoholism - Relapse - Chemoprevention. I. Soyka. M. (Michael) RC565.A This work is subject to copyright. All rights are reserved, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilm or in any other way, and storage in data banks. Duplication of this publication or parts thereof is permitted only under the provisions of the German Copyright Law of September 9, 1965, in its current version, and permission for use must always be obtained from Springer-Verlag. Violations are liable for prosecution under the German Copyright Law. Springer-Verlag Berlin Heidelberg 1996 Softcover reprint of the hardcover 1 st edition 1996 The use of general descriptive names, registered names, trademarks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regnlations and therefore free for general use. Product liability: The publisher cannot guarantee the accuracy of any information about dosage and application contained in this book. In every individual case the user must check such information by consnlting the relevant literature. Cover design: Design & Production, Heidelberg Typesetting: Scientific Publishing Services (P) Ltd, Madras SPIN: !3134!SPS Printed on acid-free paper
5 Preface Alcoholism is the most common psychiatric disorder in most developed countries and a large number of developing countries, as numerous epidemiological and clinical studies have demonstrated. Alcoholism affects the patient's life in many ways and may induce various medical and psychiatric sequelae. Over the past few decades, there have been continued efforts to improve the treatment of alcoholics. Thus different psychotherapeutic approaches have been designed and applied to alcohol treatment. Follow-up studies have demonstrated alcohol treatment to be efficient, with a significant number of patients remaining abstinent. Still, even after long-term inpatient treatment, more than 50% of the patients relapse. Relapse prevention remains a major challenge in the treatment of alcoholism. Various forms of relapse prevention including group therapy, individual psychotherapy with supportive or behavioral therapy, contingency contracting, and self-help groups have been advocated. All seem to be helpful in some cases and unsuccessful in a significant number of others. Apart from chemical aversion therapy, various psychopharmacological interventions have been tried for relapse prevention, all with limited or no success. In recent years, our knowledge of the neurochemical and neurobiological basis of alcoholism and craving for alcohol has increased significantly. The glutamatergic system has been a major focus, and acamprosate, a modulator of the glutamatergic system, is one of the most promising new pharmacological agents used in relapse prevention of alcoholism. In September 1995, a satellite symposium was held prior to the ESBRA congress to evaluate and discuss preclinical and clinical studies conducted with acamprosate. The proceedings of this symposium are summarized in this book, which also contains some important new papers on the pharmacology and clinical efficacy of acamprosate. The editor feels that this book offers a comprehensive overview on the most important studies on acamprosate conducted so far. It is hoped that many patients will benefit from anticraving drugs such as acamprosate, and perhaps this agent will help improve the treatment outcome in alcoholic patients. Munich February 1996 Michael Soyka
6 Contents Ethanol and the NMDA Receptor: Implications for Intoxication, Tolerance, Dependence, and Alcoholic Brain Damage D.M. Lovinger... 1 The Neurobiology of Craving: Potential Mechanisms for Acamprosate J. Littleton, M. al Qatari, and H. Little Pharmacodynamics and Pharmacokinetics of Acamprosate: An Overview P. Durbin, T. Hulot, and S. Chabac Actions of Acamprosate on Neurons of the Central Nervous System W. Zieglgansberger, C. Hauser, C. Wetzel, J. Putzke, G.R. Siggins, and R. Spanagel Acamprosate Decreases Alcohol Behavioral Dependence and Hypermotility After Alcohol Withdrawal But Increases Inhibitory Amino-Acids in Alcohol-Attracted Inbred Rats Using Microdialysis of the Nucleus Accumbens P. De Witte, A. Dahchour, E. Quertemont, P. Durbin, and S. Chabac Event-Related Potentials and EEG as Indicators of Central Neurophysiological Effects of Acamprosate U. Hegerl, M. Soyka, J. Gallinat, S. Ufer, U. PreuB, R. Bottlender, and H.-J. Moller Effects of Acamprosate on Verbal Learning in Healthy Young Subjects N. Kathmann, M. Soyka, J. Gallinat, and U. Hegerl Acamprosate in Clinical Practice: The French Experience H.-J. Aubin
7 VIII Contents Acamprosate Clinical Trials: Methodological Considerations for Assessment of Drinking Behaviour A.S. Potgieter and P. Lehert Acamprosate in the Treatment of Alcohol Dependence: A 6-Month Postdetoxification Study I. Pelc, o. Le Bon, P. Lehert, and P. Verbanck Contribution of Acamprosate in Maintaining Abstinence in Weaned Alcohol-Dependent Patients: Additional Results of the Second French Multicentre Study F. Paille, P. Parot, and C. Gillet Clinical Efficacy of Acamprosate in the Treatment of Alcoholism M. Soyka Subject Index
8 List of Contributors al Qatari, M., Pharmacology Group, Kings College, Manresa Road, London SW3 6LX, UK Aubin, H.-J., Centre d'alcoologie, Hopital Emile Roux, Limeil-Brevannes Cedex, France Bottlender, R., Psychiatrische Klinik der Ludwig-Maximilians-Universitat, NuBbaumstr. 7, Munchen, Germany Chabac, S., Groupe LIPHA, DiMI, 34 rue St-Romain, Lyon Cedex 8, France Dahchour, A., Laboratoire de Psychobiologie, Universite de Louvain, Place Croix-du-Sud, 1348 Louvain-Ia-Neuve, Belgium De Witte, P., Laboratoire de Psychobiologie, Universite de Louvain, Place Croix-du-Sud, 1348 Louvain-Ia-Neuve, Belgium Durbin, P., Groupe LIPHA, Centre de Recherche et de Developpement, 115 avenue Lacassagne, Lyon, France Gallinat, J., Psychiatrische Klinik der Ludwig-Maximillians-Universitat, NuBbaumstr. 7, Munchen, Germany Gillet, C., Centre d' Alcoologie, Hopital Fournier, 36 quai de la Bataille, NancyCedex, France Hauser, C., Max-Planck-Institut fur Psychiatrie, Klinisches Institut, Kraepelinstr. 2, Munchen, Germany Hegerl, U., Psychiatrische Klinik der Ludwig-Maximilians-Universitat, Nuf3baumstr. 7, Munchen, Germany Hulot, T., Groupe LIPHA, Centre de Recherche et de Developpement, 115 avenue Lacassagne, Lyon, France Kathmann, N., Psychiatrische Klinik der Ludwig-Maximilians-Universitat, NuBbaumstr. 7, Munchen, Germany
9 x List of Contributors Le Bon, 0., Laboratoire de Psychobiologie Medicale et d' Alcoologie, Universite Libre de Bruxelles (Campus Brugmann), Place Van Gehuchten 4, 1020 Brussels, Belgium Lehert, P., Departement de Sciences Economiques Appliquees, Facultes Catholiques de Mons, 7000 Mons, Belgium Little, H., Psychology Department, University of Durham, Durham, UK Littleton, J., Pharmacology Group, Kings College, Manresa Road, London SW3 6LX, UK Lovinger, D.M., Department of Molecular Physiology and Biophysics and Pharmacology, Vanderbilt University School of Medicine, Nashville, TN , USA Moller, H.-J., Psychiatrische Klinik der Ludwig-Maximilians-Universitat, NuBbaumstr. 7,80336 Miinchen, Germany Paille, F., Centre d'alcoologie, Hopital Fournier, 36 quai de la Bataille, Nancy Cedex, France Parot, P., Pharmaceutical Consultant, 12, avenue G. Pompidon, Puteaux, France Pelc, I., Laboratoire de Psychologie Medicale et d' Alcoologie, Universite Libre de Bruxelles (Campus Brugmann), Place Van Gehuchten 4, 1020 Brussels, Belgium Potgieter, A.S., Groupe LIPHA, 34 rue St-Romain, Lyon Cedex 8, France PreuB, U., Psychiatrische Klinik der Ludwig-Maximilians-Universitat, NuBbaumstr. 7, Miinchen, Germany Putzke, J., Max-Planck-Institut fur Psychiatrie, Klinisches Institut, Kraepelinstr. 2, Miinchen, Germany Quertemont, E., Laboratoire de Psychobiologie, Universite de Louvain, Place Croix-du-Sud, 1348 Louvain-Ia-Neuve, Belgium Siggins, G.R., Department of Neuropharmacology, The Scripps Research Institute, North Torrey Pines Road, La Jolla, CA 92037, USA Soyka, M., Psychiatrische Klinik der Ludwig-Maximilians-Universitat, NuBbaumstr. 7, Miinchen, Germany Spanagel, R., Max-Planck-Institut Fiir Psychiatrie, Klinisches Institut, Kraepelinstr. 2., Miinchen, Germany Ufer, S., Psychiatrische Klinik der Ludwig-Maximilians-Universitat, NuBbaumstr. 7, Miinchen, Germany
10 List of Contributors XI Verbanck, P., Laboratoire de Psychologie Medicale et d' Alcoologie, Universite Libre de Bruxelles (Campus Brugmann), Place Van Gehuchten 4, 1020 Brussels, Belgium Wetzel, C., Max-Planck-Institut fur Psychiatrie, Klinisches Institut, Kraepelinstr. 2,80804 Miinchen, Germany Zieglgansberger, W., Max-Planck-Institut fiir Psychiatrie, Klinisches Institut, Kraepelinstr. 2, Miinchen, Germany
Psychopharmacology Series 8
Psychopharmacology Series 8 Methodology of the Evaluation of Psychotropic Drugs Edited by O. Benkert, W. Maier, and K. Rickels With 19 Figures Springer-Verlag Berlin Heidelberg New York London Paris Tokyo
More informationMR Mammography (MRM) Werner A. Kaiser. Springer-Verlag Berlin Heidelberg New York London Paris Tokyo Hong Kong Barcelona Budapest
Werner A. Kaiser MR Mammography (MRM) With 648 Figures and 25 Tables Springer-Verlag Berlin Heidelberg New York London Paris Tokyo Hong Kong Barcelona Budapest Priv.-Doz., Dr. med., Dipl.-Chem. Werner
More informationAtlas of Bone Scintigraphy in the Developing Paediatric Skeleton
Klaus Hahn Sibylle Fischer Isky Gordon Atlas of Bone Scintigraphy in the Developing Paediatric Skeleton The Normal Skeleton, Variants and Pitfalls In Collaboration with J. Guillet, A. Piepsz, I. Roca and
More informationTemperature Regulation in Humans and Other Mammals
Temperature Regulation in Humans and Other Mammals Springer Berlin Heidelberg New York Barcelona Hong Kong London Milan Paris Singapore Tokyo Claus Jessen Temperature Regulation in Humans and Other Mammals
More informationIntelligence and Artificial Intelligence
Intelligence and Artificial Intelligence Springer-Verlag Berlin Heidelberg GmbH U. Ratsch M. M. Richter 1.-0. Stamatescu (Eds.) Intelligence and Artificial Intelligence An Interdisciplinary Debate With
More informationThe Psychobiology of Bulimia Nervosa
K. M. Pirke W. Vandereycken D. Ploog (Eds. ) The Psychobiology of Bulimia Nervosa With 31 Figures and 19 Tables Springer-Verlag Berlin Heidelberg New York London Paris Tokyo Privatdozent Dr. KARL MARTIN
More informationMonographs. Series Editor: U. Veronesi
Monographs Series Editor: U. Veronesi The European School of Oncology gratefully acknowledges financial support for the production of this monograph received from Farmacia (Hellas) SA, Schering-Plough
More informationMEDICAL RADIOLOGY Diagnostic Imaging
I MEDICAL RADIOLOGY Diagnostic Imaging Editors: A. L. Baert, Leuven K. Sartor, Heidelberg II Contents Springer Berlin Heidelberg New York Hong Kong London Milan Paris Tokyo III A. Adam R. F. Dondelinger
More informationB.M. Henz T. Zuberbier. J. Grabbe E. Monroe (Eds.):
B.M. Henz T. Zuberbier. J. Grabbe E. Monroe (Eds.): URTICARIA Springer Berlin Heidelberg New York Barcelona Budapest Hong-Kong London Milan Paris Santa Clara Singapore Tokyo B.M. Henz T. Zuberbier J. Grabbe
More informationInteraction Between. Mental and Physical. Needed Areas of Research. Edited by R. Ohman H. L. Freeman A. Franck Holmkvist S.
Interaction Between Mental and Physical Illness Needed Areas of Research Edited by R. Ohman H. L. Freeman A. Franck Holmkvist S. Nielzen In Collaboration with Members of the EMRC Study Group on Mental
More information167 Topics in Current Chemistry
167 Topics in Current Chemistry Marine Natural Products - Diversity and Biosynthesis Editor: Paul J. Scheuer With contributions by B. J. Baker, C.W J. Chang, G. Cimino, W H. Gerwick, R. G. Kerr, D. G.
More informationFerrozzi. Garlaschi. Bova CT of Metastases
Ferrozzi. Garlaschi. Bova CT of Metastases Springer Berlin Heidelberg New York Barcelona Hong Kong London Milan Paris Singapore Tokyo F. Ferrozzi. G. Garlaschi. D. Bova CT of Metastases With a Foreword
More informationErrors. Uroradiology. Manuel Viamonte Jr. Springer-Verlag Berlin Heidelberg New York London Paris Tokyo Hong Kong Barcelona Budapest
Manuel Viamonte Jr. Errors In Uroradiology With 148 Figures (41 Cases) in 173 Separate Illustrations Springer-Verlag Berlin Heidelberg New York London Paris Tokyo Hong Kong Barcelona Budapest Prof. Manuel
More informationExercises in Radiological Diagnosis
Exercises in Radiological Diagnosis Michel Runge Bones and Joints 170 Radiological Exercises for Students and Practitioners With 407 Illustrations Springer-Verlag Berlin Heidelberg New York London Paris
More informationIntraoperative Ultrasound Imaging in Neurosurgery
Ludwig M.Auer Vera Van Velthoven Intraoperative Ultrasound Imaging in Neurosurgery Comparison with CT and MRI With 466 Figures in 547 Separate Illustrations Springer-Verlag Berlin Heidelberg New York London
More informationMRIofthe Central Nervous System
K. Mori (Ed.) MRIofthe Central Nervous System A Pathology Atlas With the Collaboration of M. Kurisaka A. Moriki A. Sawada With 116 Case Studies and 372 Figures Springer-Verlag Tokyo Berlin Heidelberg New
More informationSPRINGER BRIEFS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY. Gerhard Bauer Joseph S. Anderson. Gene Therapy for HIV From Inception to a Possible Cure
SPRINGER BRIEFS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY Gerhard Bauer Joseph S. Anderson Gene Therapy for HIV From Inception to a Possible Cure 123 SpringerBriefs in Biochemistry and Molecular Biology For
More informationQuality Assurance Program on Stereotactic Radiosurgery
Quality Assurance Program on Stereotactic Radiosurgery Springer Berlin Heidelberg New York Barcelona Budapest Hong Kong London Milan Paris Tokyo Gunther H. Hartmann Quality Assurance Program on Stereotactic
More informationSpringer London Berlin Heidelberg New York Barcelona Budapest Hong Kong Milan Paris Santa Clara Singapore Tokyo
Focus on Cancer Springer London Berlin Heidelberg New York Barcelona Budapest Hong Kong Milan Paris Santa Clara Singapore Tokyo Robert Dunlop Cancer: Palliative Care, Springer Robert Dunlop St Christopher's
More informationThis publication and the symposium on which it was based were sponsored by an educational grant from the Janssen Research Foundation
This publication and the symposium on which it was based were sponsored by an educational grant from the Janssen Research Foundation Guidelines for Neuroleptic Relapse Prevention in Schizophrenia Proceedings
More informationAdvances in Anatomy Embryology and Cell Biology
Advances in Anatomy Embryology and Cell Biology Vol. 175 Editors F. Beck, Melbourne B. Christ, Freiburg W. Kriz, Heidelberg E. Marani, Leiden W. Kummer, Gießen R. Putz, München Y. Sano, Kyoto T. H. Schiebler,
More informationDifferential Diagnosis of Movement Disorders in Clinical Practice
Differential Diagnosis of Movement Disorders in Clinical Practice Abdul Qayyum Rana Peter Hedera Differential Diagnosis of Movement Disorders in Clinical Practice Abdul Qayyum Rana Parkinson's Clinic
More informationNew Results. in Depression Research. Edited by H. Hippius. G. L. Klerman. N. Matussek With the Assistance of M. Schmauss
New Results in Depression Research Edited by H. Hippius. G. L. Klerman. N. Matussek With the Assistance of M. Schmauss With 68 Figures Springer-Verlag Berlin Heidelberg New York London Paris Tokyo Professor
More informationCone Beam CT of the Head and Neck
Cone Beam CT of the Head and Neck Chung How Kau Kenneth Abramovitch Sherif Galal Kamel Marko Bozic Cone Beam CT of the Head and Neck An Anatomical Atlas Professor Chung How Kau University of Alabama Birmingham
More informationCytologyin Gynecological Practice
P. Stoll G. Dallenbach-Hellweg Cytologyin Gynecological Practice An Atlas of Phase-Contrast Microscopy Second Edition with 149 Figures Springer-Verlag Berlin Heidelberg New York London Paris Tokyo Hong
More informationMEDICAL RADIOLOGY. Diagnostic Imaging and Radiation Oncology - Softcover Edition. A. L. Baert, Leuven EH. W. Heuck, Stuttgart. J. E.
MEDICAL RADIOLOGY Diagnostic Imaging and Radiation Oncology - Softcover Edition Editorial Board Founding Editors L. W. Brady, M. W. Donner (t), H.-P. Heilmann, EH. W. Heuck Current Editors Diagnostik Imaging
More informationThe Pharmacology of Alcohol and Drugs of Abuse and Addiction
The Pharmacology of Alcohol and Drugs of Abuse and Addiction Norman S. Miller The Pharmacology of Alcohol and Drugs of Abuse and Addiction Springer-Verlag New York Berlin Heidelberg London Paris Tokyo
More informationNeurobiological Bases of Abnormal Aggression and Violent Behaviour
Neurobiological Bases of Abnormal Aggression and Violent Behaviour . József Haller Neurobiological Bases of Abnormal Aggression and Violent Behaviour József Haller Department of Behavioral Neurobiology
More informationM. Ackenheil. B. Bondy. R. Engel. M. Ermann. N. Nedopil (Eds.) Implications of Psychopharmacology to Psychiatry
M. Ackenheil. B. Bondy. R. Engel. M. Ermann. N. Nedopil (Eds.) Implications of Psychopharmacology to Psychiatry Springer Berlin Heidelberg New York Barcelona Budapest Hong Kong London Milan Paris Tokyo
More informationRecent Research in Psychology
Recent Research in Psychology Gerhard Stemmler Differential Psychophysiology: Persons in Situations L z.~.s;-----, Springer-Verlag Berlin Heidelberg New York London Paris Tokyo Hong Kong Barcelona Budapest
More informationTopics in Neuroscience
Topics in Neuroscience Managing Editor: GIANCARLO COMI Co-Editor: JACOPO MELDOLESI Associate Editors: UGO ECARI MASSIMO FILIPPI GIANVITO MARTINO Springer-V erlag Italia Srl. A. Vincent G. Martino (Eds)
More informationProgress in Social Psychiatry in Japan
Progress in Social Psychiatry in Japan Yoshibumi Nakane Progress in Social Psychiatry in Japan An Approach to Psychiatric Epidemiology Yoshibumi Nakane Department of Neuropsychiatry Nagasaki University
More informationProgress in Inflammation Research
Progress in Inflammation Research Series Editor Prof. Dr. Michael J. Parnham PLiVA Research Institute Prilaz baruna Filipovica 25 10000 Zagreb Croatia Forthcoming titles: Migraine: a Neuroinflammatory
More informationThe Central Nervous System in AIDS
IArtigas. G. Grosse F. Niedobitek (Eds.) The Central Nervous System in AIDS Neurology Radiology Pathology Ophthalmology With a Foreword by M. L'age With 128 Figures and 25 Tables Springer-Verlag Berlin
More informationTopics in Colorectal Disease
R. John Nicholls Neil 1. McC. Mortensen John M.A. Northover (Eds.) Topics in Colorectal Disease With 35 Figures, Some in Colour and 31 Tables Springer-Verlag Berlin Heidelberg New York London Paris Tokyo
More informationContributions to Lexical Semantics
Right Hemisphere Contributions to Lexical Semantics Edited by Christine Chiarello With 25 Figures Springer-Verlag Berlin Heidelberg New York London Paris Tokyo CHRISTINE CHIARELLO, Ph. D. Syracuse University
More informationWorld Health Organization
World Health Organization The series International Histological Classification of Tumours consists of the following volumes. Each of these volumes - apart from volumes 1 and 2, which have already been
More informationA. Cesarani D. Alpini. Vertigo and Dizziness Rehabilitation
A. Cesarani D. Alpini Vertigo and Dizziness Rehabilitation Springer Berlin Heidelberg New York Barcelona Hong Kong London Milan Paris Singapore Tokyo Antonio Cesarani Dario Alpini Vertigo and Dizziness
More informationUrate Deposition in Man and its Clinical Consequences
U. Gresser, N. Zöllner (Eds.) Urate Deposition in Man and its Clinical Consequences With Contributions by R. A. De Abreu, G. van den Berghe, G. Calabrese, D. J. McCarty, B. T. Emmerson, B. Gathof, M. Gonella,
More informationCongenital Hip Disease in Adults
Congenital Hip Disease in Adults George Hartofilakidis George C. Babis Kalliopi Lampropoulou-Adamidou Congenital Hip Disease in Adults George Hartofilakidis, MD, FACS Orthopaedic Department Medical School
More informationThe Rheumatoid Hip. Heiner Thabe. Springer-Verlag Berlin Heidelberg New York London Paris Tokyo Hong Kong Barcelona. With 87 Figures and 24 Tables
Heiner Thabe The Rheumatoid Hip With 87 Figures and 24 Tables Translated by Julia and David Roseveare Springer-Verlag Berlin Heidelberg New York London Paris Tokyo Hong Kong Barcelona Dr. med. Heiner Thabe
More informationNeuroblastoma. mibg in its Diagnosis and Management. Judy Moyes' V. Ralph McCready Ann Fullbrook
Judy Moyes' V. Ralph McCready Ann Fullbrook Neuroblastoma mibg in its Diagnosis and Management With 241 Figures Springer-Verlag London Berlin Heidelberg New York Paris Tokyo Judy S.E. Moyes. MA (Cantab).
More informationManagement of Headache and Headache Medications
Management of Headache and Headache Medications Lawrence D. Robbins, M.D. Management of Headache and Headache Medications Foreword by Jerome Goldstein, M.D. Springer-Verlag New York Berlin Heidelberg London
More informationDiagnostic Imaging of the Liver
S. Sakuma T. Ishigaki T. Takeuchi Diagnostic Imaging of the Liver Biliary Tract and Pancreas Data Analysis and Diagnostic Procedures With 312 Figures in 932 Separate Illustrations Springer-Verlag Berlin
More informationProgressive Multiple Sclerosis
Progressive Multiple Sclerosis Alastair Wilkins Editor Progressive Multiple Sclerosis Editor Alastair Wilkins, M.A., M.B., B.Chir, Ph.D., FRCP Department of Neurology Frenchay Hospital Bristol UK ISBN
More informationHomocysteine. Related Vitamins and Neuropsychiatric Disorders
Homocysteine Related Vitamins and Neuropsychiatric Disorders Springer Paris Berlin Heidelberg New York Hong Kong London Milan Tokyo Christina Bolander-Gouaille Teodoro Bottiglieri Homocysteine Related
More informationVaricella-Zoster Virus Epithelial Keratitis in Herpes Zoster Ophthalmicus
Varicella-Zoster Virus Epithelial Keratitis in Herpes Zoster Ophthalmicus Helena M. Tabery Varicella-Zoster Virus Epithelial Keratitis in Herpes Zoster Ophthalmicus In Vivo Morphology in the Human Cornea
More informationSeries in Psychopathology. Series Editor Lauren B. Alloy
Series in Psychopathology Series Editor Lauren B. Alloy Michael W. O'Hara Postpartum Depression Causes and Consequences With a Foreword by Lee S. Cohen, M.D. With 22 Illustrations Springer-Verlag New York
More informationEvidence-Based Forensic Dentistry
Evidence-Based Forensic Dentistry Balwant Rai Jasdeep Kaur Evidence-Based Forensic Dentistry Authors Balwant Rai Earth and Life Sciences Vrije Universiteit Amsterdam and ILEWG Amsterdam The Netherlands
More informationDeep Brain Stimulation for Neurological Disorders
Deep Brain Stimulation for Neurological Disorders Toru I t a k u ra Editor Deep Brain Stimulation for Neurological Disorders Theoretical Background and Clinical Application Editor Toru Itakura, MD, PhD
More informationDermatological Diseases of the Nose and Ears
Dermatological Diseases of the Nose and Ears Can Baykal K. Didem Yazganoğlu Dermatological Diseases of the Nose and Ears An Illustrated Guide Prof. Dr. Can Baykal Dr. K. Didem Yazganoğlu Istanbul University
More informationWhite Coat Hypertension
White Coat Hypertension Giuseppe Mancia Guido Grassi Gianfranco Parati Alberto Zanchetti White Coat Hypertension An Unresolved Diagnostic and Therapeutic Problem Giuseppe Mancia Emeritus Professor University
More informationMEDICAL RADIOLOGY. Diagnostic Imaging and Radiation Oncology
MEDICAL RADIOLOGY Diagnostic Imaging and Radiation Oncology Editorial Board Founding Editors: L.W. Brady, M.W. Donner (t), H.-P. Heilmann, F.H.W. Heuck Current Editors: A.L. Baert, Leuven. L.W. Brady,
More informationTestosterone. Substitution. Action Deficiency. E. Nieschlag H. M. Behre (Eds.) Editorial Assistant: S. Nieschlag. With 78 Figures and 20 Tables
E. Nieschlag H. M. Behre (Eds.) Testosterone Action Deficiency Substitution Editorial Assistant: S. Nieschlag With 78 Figures and 20 Tables Springer-Verlag Berlin Heidelberg New York London Paris Tokyo
More informationPositive Family Therapy
N. Peseschkian Positive Family Therapy The Family as Therapist Springer-Verlag Berlin Heidelberg N ew York Tokyo Dr. med. Nossrat Peseschkian Facharzt flir Neuroiogie und Psychiatrie Psychotherapie An
More informationAIDS Testing Methodology and Management Issues
AIDS Testing Gerald Schochetman J. Richard George Editors AIDS Testing Methodology and Management Issues Foreword by Walter R. Dowdle With 38 Illustrations Springer-Verlag New York Berlin Heidelberg London
More informationSpringer-Verlag Berlin Heidelberg GmbH
Clinical Acupuncture Springer-Verlag Berlin Heidelberg GmbH Gabriel Stux Richard Hammerschlag (Editors) Clinical Acupuncture Scientific Basis With Contributions by B. M. Berman, S. Birch, C. M. Cassidy,
More informationPolymyalgia Rheumatica and Giant Cell Arteritis
Jozef Rovenský Burkhard F. Leeb Howard Bird Viera Štvrtinová Richard Imrich Editors Polymyalgia Rheumatica and Giant Cell Arteritis SpringerWienNewYork Editors Prof. Jozef Rovenský, MD, DSc, FRCP, Slovakia
More informationMorbid Obesity in Adolescents
Morbid Obesity in Adolescents ThiS is a FM Blank Page Kurt Widhalm Gerhard Prager Editors Morbid Obesity in Adolescents Conservative Treatment and Surgical Approaches Editors Kurt Widhalm Department of
More informationAlternate Methods. of Benign Prostatic Hyperplasia
N.A.Romas E.D.Vaughan (Eds.) Alternate Methods in the Treatment of Benign Prostatic Hyperplasia With 67 Figures and 26 Tables Springer-Verlag Berlin Heidelberg New York London Paris Tokyo Hong Kong Barcelona
More informationKai-Uwe Schmitt. Peter F. Niederer Felix Walz. Trauma Biomechanics. Introduetion to Aecidentallnjury. ~ Springer
Trauma Biomechanics Kai-Uwe Schmitt. Peter F. Niederer Felix Walz Trauma Biomechanics Introduetion to Aecidentallnjury ~ Springer PD Dr. KAI-UWE SCHMITT Prof. Dr. sc. techno PETER F. NIEDERER Prof. Dr.
More informationDiseases of the Spinal Cord
Diseases of the Spinal Cord Elke Hattingen Stefan Weidauer Matthias Setzer Johannes C. Klein Frank Vrionis Editors Diseases of the Spinal Cord Novel Imaging, Diagnosis and Treatment Editors Elke Hattingen
More informationMark W.J. Strachan Brian M. Frier. Insulin Therapy. A Pocket Guide
Insulin Therapy Mark W.J. Strachan Brian M. Frier Insulin Therapy A Pocket Guide Mark W.J. Strachan, MD, FRCP (Ed) Metabolic Unit Western General Hospital Edinburgh United Kingdom Brian M. Frier, MD,
More informationAlexander N. Sencha Elena V. Evseeva Mikhail S. Mogutov Yury N. Patrunov. Breast Ultrasound
Breast Ultrasound Alexander N. Sencha Elena V. Evseeva Mikhail S. Mogutov Yury N. Patrunov Breast Ultrasound Alexander N. Sencha Department of Ultrasound Diagnostics Yaroslavl Railway Clinic Yaroslavl
More informationHans-Jakob Steiger, Robert Schmid-Elsaesser, Alexander Muacevic, Hartmut Brilckmann und Berndt Wowra
Hans-Jakob Steiger, Robert Schmid-Elsaesser, Alexander Muacevic, Hartmut Brilckmann und Berndt Wowra Neurosurgery of Arteriovenous Malformations and Fistulas A Multimodal Approach Springer-Verlag Wien
More informationMusculoskeletal Health in Women
Musculoskeletal Health in Women Elinor Mody Elizabeth Matzkin Editors Musculoskeletal Health in Women Editors Elinor Mody, MD Department of Rheumatology Gretchen and Edward Fish Center for Women s Health
More informationCerebral Blood Flow, Metabolism, and Head Trauma
Cerebral Blood Flow, Metabolism, and Head Trauma Christian W. Kreipke Editors Jose A. Rafols Cerebral Blood Flow, Metabolism, and Head Trauma The Pathotrajectory of Traumatic Brain Injury Editors Christian
More informationFriedrich Kummer (ed.) Treatment of Asthma: The long-acting beta-2-agonists. Springer WienN ewyork
Friedrich Kummer (ed.) Treatment of Asthma: The long-acting beta-2-agonists Springer WienN ewyork Prof. Dr. med. Friedrich Kummer 2. Medizinische Abteilung mit Lungenkrankheiten und Tuberkulose, Wilhelminenspital,
More informationPolymyalgia Rheumatica and Giant Cell Arteritis
Jozef Rovenský Burkhard F. Leeb Howard Bird Viera Štvrtinová Richard Imrich Editors Polymyalgia Rheumatica and Giant Cell Arteritis SpringerWienNewYork Editors Prof. Jozef Rovenský, MD, DSc, FRCP, Slovakia
More informationAttention-Deficit Hyperactivity Disorder (ADHD) in Adults
Attention-Deficit Hyperactivity Disorder (ADHD) in Adults Key Issues in Mental Health Vol. 176 Series Editors A. Riecher-Rössler Basel M. Steiner Hamilton Attention-Deficit Hyperactivity Disorder (ADHD)
More informationUrinary Tract Infection
Urinary Tract Infection Abhay Rané Ranan Dasgupta Editors Urinary Tract Infection Clinical Perspectives on Urinary Tract Infection Editors Abhay Rané, MS, FRCS, FRCS (Urol) Department of Urology Surrey
More informationSpringerBriefs in Cancer Research
SpringerBriefs in Cancer Research For further volumes: http://www.springer.com/series/10786 Natalia Aptsiauri Angel Miguel Garcia-Lora Teresa Cabrera MHC Class I Antigens In Malignant Cells Immune Escape
More informationRadiology Illustrated
Radiology Illustrated For further volumes: http://www.springer.com/series/11755 In-One Kim Editor Radiology Illustrated: Pediatric Radiology Editor In-One Kim, M.D. Department of Radiology Seoul National
More informationSymposium in Immunology IV
M. M. Eibl C. Huber H. H. Peter U. Wahn (Eds.) Symposium in Immunology IV Allergic Diseases With 34 Figures and 14 Tables Springer-Verlag Berlin Heidelberg New York London Paris Tokyo Hong Kong Barcelona
More informationSmall Supernumerary Marker Chromosomes (ssmc)
Small Supernumerary Marker Chromosomes (ssmc) . Thomas Liehr Small Supernumerary Marker Chromosomes (ssmc) A Guide for Human Geneticists and Clinicians With contributions by Unique (The Rare Chromosome
More informationErnst Schering Research Foundation Workshop 30 Therapeutic Vaccination Strategies
Ernst Schering Research Foundation Workshop 30 Therapeutic Vaccination Strategies Springer-Verlag Berlin Heidelberg GmbH Ernst Schering Research Foundation Workshop 30 Therapeutic Vaccination Strategies
More informationExperimental Hypertension and Therapeutic Progress: Vasodilation and Beyond
B. Garthoff A.M. Knorr W.-D. Busse F. Seuter (Eds.) Experimental Hypertension and Therapeutic Progress: Vasodilation and Beyond With 42 Figures and 10 Tables Springer-Verlag Berlin Heidelberg New York
More informationTherapeutic rtms in Neurology
Therapeutic rtms in Neurology Thomas Platz Editor Therapeutic rtms in Neurology Principles, Evidence, and Practice Recommendations Editor Thomas Platz BDH-Klinik Greifswald Ernst-Moritz-Arndt Universität
More informationJohn Papadopoulos David R. Schwartz Consulting Editor. Pocket Guide to Critical Care Pharmacotherapy Second Edition
John Papadopoulos David R. Schwartz Consulting Editor Pocket Guide to Critical Care Pharmacotherapy Second Edition 123 Pocket Guide to Critical Care Pharmacotherapy John Papadopoulos Author David R. Schwartz
More informationZayas, Functionality of Proteins in Food
Zayas, Functionality of Proteins in Food Springer-Verlag Berlin Heidelberg GmbH Joseph F. Zayas Functionality of Proteins in Food Wit h 86 Figures and 21 Tables Springer Prof. Dr. Joseph F. Zayas t Kansas
More informationCurrent Topics in Pathology
Current Topics in Pathology 80 Managing Editors C.L. Berry E. Grundmann Editorial Board H. Cottier, P.I Dawson, H. Denk, C.M. Fenoglio-Preiser Ph.U.Heitz, O.H.Iversen, F.Nogales, N.Sasano, G.Seifert J.C.E.
More informationPrevention of Disease Progression Throughout the Cardiovascular Continuum
Prevention of Disease Progression Throughout the Cardiovascular Continuum Springer-Verlag Berlin Heidelberg GmbH L.E. RYDEN (ED.) Prevention of Disease Progression Throughout the Cardiovaseular Continuum
More informationCounseling and Action
Counseling and Action Richard A. Young José F. Domene Ladislav Valach Editors Counseling and Action Toward Life-Enhancing Work, Relationships, and Identity 1 3 Editors Richard A. Young Department of Educational
More informationOrthopaedic Diagnosis
Hubert A. Sis sons. Ronald O. Murray H.B.S. Kemp Orthopaedic Diagnosis Clinical, Radiological and Pathological Coordinates With 534 Figures, Many in Colour Springer-Verlag Berlin Heidelberg New York Tokyo
More informationMuscle Pain: Understanding the Mechanisms
Muscle Pain: Understanding the Mechanisms Siegfried Mense l Editors Robert D. Gerwin Muscle Pain: Understanding the Mechanisms Editors Prof. Dr. Siegfried Mense Universität Heidelberg Medizinische Fakultät
More informationThe. Vertebral Artery. Pathology and Surgery. Bernard George. Claude Laurian. Springer-Verlag Wi en New York
The Vertebral Artery Pathology and Surgery Bernard George Claude Laurian Springer-Verlag Wi en New York Bernard George, M.D. Department of Neurosurgery, H6pital Lariboisiere, Paris, France Claude Laurian,
More informationE. Nieschlag H. M. Behre (Eds.) Testosterone
E. Nieschlag H. M. Behre (Eds.) Testosterone Springer Berlin Heidelberg New York Barcelona Budapest Hong Kong London Milan Paris Santa Clara Singapore Tokyo E. Nieschlag H. M. Behre (Eds.) Testosterone
More informationin Asthmology Methods Luigi Allegra. Pier Carlo Braga Roberto Dal Negro (Eds.)
Luigi Allegra. Pier Carlo Braga Roberto Dal Negro (Eds.) Methods in Asthmology With 107 Figures and 53 Tables Springer-Verlag Berlin Heidelberg New York London Paris Tokyo Hong Kong Barcelona Budapest
More informationRadiation Therapy for Skin Cancer
Radiation Therapy for Skin Cancer Armand B. Cognetta Jr. William M. Mendenhall Editors Radiation Therapy for Skin Cancer Editors Armand B. Cognetta Jr. Dermatology Associates of Tallahassee Chief, Division
More informationVolume 162. Handbook of Experimental Pharmacology. w. Rosenthal, Berlin. Editor-in-Chief K. Starke, Freiburg i. Br.
Handbook of Experimental Pharmacology Volume 162 Editor-in-Chief K. Starke, Freiburg i. Br. Editorial Board G.V.R. Born, London M. Eichelbaum, Stuttgart D. Ganten, Berlin F. Hofmann, Miinchen B. Kobilka,
More informationRespiratory Medicine Series Editor: Sharon I.S. Rounds. Marc A. Judson Editor. Pulmonary Sarcoidosis A Guide for the Practicing Clinician
Respiratory Medicine Series Editor: Sharon I.S. Rounds Marc A. Judson Editor Pulmonary Sarcoidosis A Guide for the Practicing Clinician Respiratory Medicine Series Editor: Sharon I.S. Rounds For further
More informationMinimally Invasive Gynecological Surgery
Minimally Invasive Gynecological Surgery O l av Is t re Editor Minimally Invasive Gynecological Surgery Editor Olav Istre, MD, PhD Fredriksberg Denmark ISBN 978-3-662-44058-2 ISBN 978-3-662-44059-9 (ebook)
More informationMastering Rhinoplasty: A Comprehensive Atlas of Surgical Techniques with Integrated Video Clips. Rollin K. Daniel
Mastering Rhinoplasty: A Comprehensive Atlas of Surgical Techniques with Integrated Video Clips Rollin K. Daniel Rollin K. Daniel Mastering Rhinoplasty A Comprehensive Atlas of Surgical Techniques with
More informationBasel Freiburg. Paris London NewYork New Delhi Bangkok Singapore Tokyo Sydney
The New Structuralism in Cognitive Development Contributions to Human Development Vol. 23 Series Editor Deanna Kuhn, New York, N.Y. KARGER Basel Freiburg. Paris London NewYork New Delhi Bangkok Singapore
More informationTadaaki Kirita Ken Omura Editors. Oral Cancer. Diagnosis and Therapy
Oral Cancer Tadaaki Kirita Ken Omura Editors Oral Cancer Diagnosis and Therapy Editors Tadaaki Kirita Department of Oral and Maxillofacial Surgery Nara Medical University Nara, Japan Ken Omura Oral Cancer
More informationLow and Lower Fertility
Low and Lower Fertility Ronald R. Rindfuss Minja Kim Choe Editors Low and Lower Fertility Variations across Developed Countries Editors Ronald R. Rindfuss Department of Sociology and Carolina Population
More informationThomas Reinhard Frank Larkin Editors. Corneal Disease. Recent Developments in Diagnosis and Therapy
Corneal Disease Thomas Reinhard Frank Larkin Editors Corneal Disease Recent Developments in Diagnosis and Therapy Editors Prof. Dr. med. Thomas Reinhard University Eye Hospital Freiburg Germany Dr. Frank
More informationThe Olfactory System
The Olfactory System Editor The Olfactory System From Odor Molecules to Motivational Behaviors Editor Department of Physiology The University of Tokyo Tokyo, Japan ISBN 978-4-431-54375-6 ISBN 978-4-431-54376-3
More informationTransesophageal Echocardiography
N. Kolev, G. Huemer, M. Zimpfer Transesophageal Echocardiography A New Monitoring Technique Springer-Verlag Wien New York Nikolai Kolev, MD, FACC Research Cardiologist Associate in Anesthesia and Consultant
More informationSSSP. Springer Series in Social Psychology
SSSP Springer Series in Social Psychology SSSP Changing Conceptions of Crowd Mind and Behavior Edited by Carl R Graumann and Serge Moscovici Springer-Verlag New York Berlin Heidelberg Tokyo Carl F. Graumann
More information