Material Safety Data Sheet

Transcription

1 Material Safety Data Sheet Issuing Date 02-May-2007 MSDS PN: REV. L 1. PRODUCT AND COMPANY IDENTIFICATION Product Name Product Code(s) Trade Name(s) Recommended Use Methanol , N METHYL ALCOHOL;CARBINOL; METHYL HYDROXIDE; MONOHYDROXYMETHANE; METHYLOL; WOOD ALCOHOL; WOOD SPIRIT; WOOD NAPHTHA; COLONIAL SPIRIT; COLUMBIAN SPIRIT; PYROXYLIC SPIRIT;420A REAGENT #5 For research use only. Not for use in diagnostic procedures. Supplier Address APPLIED BIOSYSTEMS 850 LINCOLN CENTRE DRIVE FOSTER CITY CA USA TELEPHONE: (650) (USA) Emergency Telephone Number CHEMTREC: (INTERNATIONAL) (NORTH AMERICA) 2. HAZARDS IDENTIFICATION DANGER! Emergency Overview FLAMMABLE LIQUID AND VAPOR POISON! Cannot be made non-poisonous. May be fatal or cause blindness if swallowed. MAY BE FATAL IF SWALLOWED Harmful by inhalation Harmful in contact with skin Irritating to eyes, respiratory system and skin Causes central nervous system depression May cause adverse liver effects May cause adverse kidney effects Appearance Clear Physical State Liquid Odor Alcohol Potential Health Effects Principle Routes of Exposure Acute Toxicity Eyes Skin Inhalation, Skin contact, Eye contact. Irritating to eyes. Harmful in contact with skin. May be absorbed through the skin in harmful amounts. May cause irritation. Prolonged skin contact may defat the skin and produce dermatitis. Page 1 / 9

2 Inhalation Ingestion Chronic Effects Aggravated Medical Conditions Interactions with Other Chemicals Environmental Hazard Harmful by inhalation. Irritating to respiratory system. May cause central nervous system depression with nausea, headache, dizziness, vomiting, and incoordination. After a latent period of 8-24 hours, vision and nervous system effects can occur, including temporary or permanent blindness. May be fatal or cause blindness if swallowed. Ingestion may cause gastrointestinal irritation, nausea, vomiting and diarrhea. May cause central nervous system depression. May cause adverse liver effects. May cause adverse kidney effects. Repeated or prolonged exposure may cause central nervous system damage. Central nervous system. Gastrointestinal tract. Preexisting eye disorders. Skin disorders. Liver disorders. Kidney disorders. Use of alcoholic beverages may enhance toxic effects. See Section 12 for additional Ecological information. 3. COMPOSITION/INFORMATION ON INGREDIENTS Chemical Name CAS-No Weight % FIRST AID MEASURES General Advice Eye Contact Skin Contact Inhalation Ingestion Notes to Physician Protection of First-aiders Immediate medical attention is required. Show this safety data sheet to the doctor in attendance. Immediately flush with plenty of water. After initial flushing, remove any contact lenses and continue flushing for at least 15 minutes. Keep eye wide open while rinsing. Do not rub affected area. Call a physician immediately. Wash off immediately with plenty of water. Consult a physician if necessary. Immediate medical attention is required. Move to fresh air in case of accidental inhalation of vapors. If not breathing, give artificial respiration. Avoid direct contact with skin. Use barrier to give mouth-to-mouth resuscitation. Call a physician or Poison Control Center immediately. Rinse mouth. Drink plenty of water. Do not induce vomiting without medical advice. Never give anything by mouth to an unconscious person. Ethanol may inhibit methanol metabolism. Treat symptomatically. Use personal protective equipment. Avoid contact with skin, eyes and clothing. Remove all sources of ignition. 5. FIRE-FIGHTING MEASURES Flammable Properties HIGHLY FLAMMABLE: Will be easily ignited by heat, sparks or flames. Flash Point 11 C / 52 F Suitable Extinguishing Media Explosion Data Sensitivity to mechanical impact Alcohol-resistant foam. Dry chemical. Carbon dioxide (CO2). Cool containers with flooding quantities of water until well after fire is out. None. Page 2 / 9

3 Sensitivity to static discharge Yes. Specific Hazards Arising from the Chemical Flammable. Vapors may travel to areas away from work site before igniting/flashing back to vapor source. Protective Equipment and Precautions for Firefighters In the event of fire, wear self contained breathing apparatus. NFPA Health Hazard 3 Flammability 3 Stability 0 Physical and Chemical Hazards - HMIS Health Hazard 3* Flammability 3 Stability 0 Personal Precautions - 6. ACCIDENTAL RELEASE MEASURES Personal Precautions Methods for Containment Methods for Cleaning Up Use personal protective equipment. Ensure adequate ventilation. Remove all sources of ignition. Evacuate personnel to safe areas. Keep people away from and upwind of spill/leak. Prevent further leakage or spillage if safe to do so. Dam up. Soak up with inert absorbent material (e.g. sand, silica gel, acid binder, universal binder, sawdust). Pick up and transfer to properly labeled containers. Other Information Refer to protective measures listed in Sections 7 and HANDLING AND STORAGE Handling Storage Wear personal protective equipment. Avoid contact with skin, eyes and clothing. Ensure adequate ventilation. Do not breathe vapors or spray mist. In case of insufficient ventilation, wear suitable respiratory equipment. Keep away from open flames, hot surfaces and sources of ignition. Take necessary action to avoid static electricity discharge (which might cause ignition of organic vapors). Use only in an area containing flame proof equipment. Keep tightly closed in a dry and cool place. Keep away from heat and sources of ignition. Keep in properly labeled containers. Keep out of the reach of children. 8. EXPOSURE CONTROLS / PERSONAL PROTECTION Exposure Guidelines Chemical Name ACGIH TLV OSHA PEL NIOSH IDLH TWA: 200 ppm Skin STEL: 250 ppm TWA: 200 ppm TWA: 260 mg/m 3 STEL: 250 ppm STEL: 325 mg/m 3 Skin TWA: 200 ppm 6000 ppm NIOSH IDLH: Immediately Dangerous to Life or Health Engineering Measures Personal Protective Equipment Eye/Face Protection Skin and Body Protection Respiratory Protection Showers, eyewash stations, and ventilation systems. Tightly fitting safety goggles. Impervious clothing. In case of insufficient ventilation wear suitable respiratory equipment. Page 3 / 9

4 Hygiene Measures When using, do not eat, drink or smoke. Regular cleaning of equipment, work area and clothing. Remove and wash contaminated clothing before re-use. Keep away from food, drink and animal feeding stuffs. 9. PHYSICAL AND CHEMICAL PROPERTIES Appearance Clear. Odor Alcohol. Odor Threshold 100 ppm. Physical State Liquid. ph No information available. Flash Point 11 C / 52 F Autoignition Temperature 385 C / 725 F Decomposition Temperature No information available. Boiling Point/Range 65 C / 149 F Melting Point/Range -94 C / -137 F Flammability Limits in Air Upper 36% Lower 6% Explosion Limits No information available. Specific Gravity Water Solubility Completely soluble. Solubility Ether, Benzene, Alcohol, Acetone, Chloroform, Ketone, Organic solvents. Evaporation Rate 4.6 (BuAc = 1) Vapor Pressure 97.25&20 Vapor Density 1.1 VOC Content 100% Viscosity C Partition Coefficient (noctanol/water) No information available. 10. STABILITY AND REACTIVITY Stability Incompatible Products Conditions to Avoid Stable under recommended storage conditions. Strong oxidizing agents. Contact with metals (aluminum, zinc, tin) may release hydrogen gas. Heat, flames and sparks. Extremes of temperature and direct sunlight. Hazardous Decomposition Products Carbon monoxide (CO). Carbon dioxide (CO2). Formaldehyde. Hazardous Polymerization Hazardous polymerization does not occur. 11. TOXICOLOGICAL INFORMATION Acute Toxicity Page 4 / 9

5 Product Information Toxic by inhalation, in contact with skin and if swallowed. Component Information Chemical Name LD50 Oral LD50 Dermal LC50 Inhalation 5628 mg/kg ( Rat ) mg/kg ( Rabbit ) ppm ( Rat ) 4 h 83.2 mg/l ( Rat ) 4 h Chronic Toxicity Chronic Toxicity Repeated or prolonged exposure may cause central nervous system damage. Reproductive Toxicity Target Organ Effects Other Adverse Effects The product contains no substances known to be hazardous to health in concentrations which need to be taken into account. Central nervous system (CNS), Eyes, Gastrointestinal tract (GI), Respiratory system, Skin, Liver, Kidney. Toxic: danger of very serious irreversible effects through inhalation, in contact with skin and if swallowed. Inhalation of high vapor concentrations may cause symptoms like headache, dizziness, tiredness, nausea and vomiting. 12. ECOLOGICAL INFORMATION Ecotoxicity Ecotoxicity effects. Chemical Name Toxicity to Algae Toxicity to Fish Microtox Daphnia Magna (Water Flea) LC50= mg/l Oncorhynchus mykiss 96 h LC50= mg/l Pimephales promelas 96 h EC50 = mg/l 25 min EC50 = mg/l 15 min EC50 = mg/l 5 min Persistence and Degradability No information available. Chemical Name Log Pow DISPOSAL CONSIDERATIONS Waste Disposal Method This material, as supplied, is a hazardous waste according to federal regulations (40 CFR 261). Contaminated Packaging US EPA Waste Number Do not re-use empty containers. Dispose of in accordance with local regulations. D001 Chemical Name RCRA RCRA - Basis for Listing RCRA - D Series Wastes RCRA - U Series Wastes Included in waste stream: waste number U154 (Ignitable F039 waste) This product contains one or more substances that are listed with the State of California as a hazardous waste. Chemical Name California Hazardous Waste Status Toxic; Ignitable Page 5 / 9

6 14. TRANSPORT INFORMATION DOT TDG MEX ICAO IATA Methanol,3,(6.1),,PG METHANOL,3,,PG Proper Shipping Name Metanol Metanol,3, Methanol,3(6.1),,PG ERG Code 3P,Methanol,3(6.1),PG IMDG/IMO EmS No. F-E, S-D, Methanol,3(6.1),PG RID Page 6 / 9

7 14. TRANSPORT INFORMATION Classification Code FT1 Methanol,3,,RID ADR/RID-Labels ADR ADN Classification Code FT1 ADR/RID-Labels Classification Code FT1 Special Provisions 279 Methanol,3, Hazard Labels Limited Quantity 1 L Page 7 / 9

8 International Inventories 15. REGULATORY INFORMATION TSCA DSL EINECS/ELINCS ENCS CHINA KECL PICCS AICS Listed on inventory. For purposes of 40 CFR , this product is for Research and Development (R&D) Use Only. U.S. Federal Regulations SARA 313 Section 313 of Title I of the Superfund Amendments and Reauthorization Act of 1986 (SARA). This product contains a chemical or chemicals which are subject to the reporting requirements of the Act and Title 40 of the Code of Federal Regulations, Part 372: Chemical Name CAS-No Weight % SARA Threshold Values SARA 311/312 Hazard Categories Acute Health Hazard Chronic Health Hazard Fire Hazard Sudden Release of Pressure Hazard Reactive Hazard Yes Yes Yes No No Clean Water Act This product does not contain any substances regulated as pollutants pursuant to the Clean Water Act (40 CFR and 40 CFR ) CERCLA This material, as supplied, contains one or more substances regulated as a hazardous substance under the Comprehensive Environmental Response Compensation and Liability Act (CERCLA) (40 CFR 302). U.S. State Regulations Chemical Name Hazardous Substances RQs Extremely Hazardous Substances RQs 5000 lb California Proposition 65 This product does not contain any Proposition 65 chemicals. U.S. State Right-to-Know Regulations Chemical Name Massachusetts New Jersey Pennsylvania Illinois Rhode Island X X X X X International Regulations Mexico - Grade Serious risk, Grade 3 Page 8 / 9

9 Canada Chemical Name Carcinogen Status Exposure Limits Mexico: TWA= 200 ppm Mexico: TWA= 260 mg/m 3 Mexico: STEL= 310 mg/m 3 Mexico: STEL= 250 ppm This product has been classified in accordance with the hazard criteria of the Controlled Products Regulations (CPR) and the MSDS contains all the information required by the CPR. WHMIS Hazard Class B2 Flammable liquid D2A Very toxic materials Chemical Name NPRI X Legend NPRI - National Pollutant Release Inventory 16. OTHER INFORMATION Issuing Date 02-May-2007 Revision Note No information available Disclaimer The information provided on this MSDS is correct to the best of our knowledge, information and belief at the date of its publication. The information given is designed only as a guide for safe handling, use, processing, storage, transportation, disposal and release and is not to be considered as a warranty or quality specification. The information relates only to the specific material designated and may not be valid for such material used in combination with any other material or in any process, unless specified in the text. End of MSDS Page 9 / 9