Bead Chemiluminescense IMMULITE 2000, 2000 XPI & 2500

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1 Bead Chemiluminescense IMMULITE 2000, 2000 XPI & 2500 For internal use only / Copyright Siemens AG All rights reserved.

2 المانھای مھم در روشھای کميلومينسانس: کميلومينسانسر مرحله جداسازی.1.2 Page 2

3 Chemilumiencsencers : مھم کميلومينسنسر ھا ويژگيھای سايز مولکولی نوع لومينسانس.1.2 Page 3

4 Chemiluminecser Size Page 4

5 Chemilumiencsencer Size smaller size decreases blockage of Binding sites, increases diffusion rates, and increases the assay sensitivity Page 5

6 Light emission Page 6

7 Light emission Page 7

8 Separation Page 8

9 Breadth of Menu * Currently 200 FDA approved Page 9

10 Breadth Of Menu Not all assays are available in all countries Page 10 Allergy Anemia Bone Cardiovascular Diabetes Growth Metabolic Infectious Disease Congenital Reproductive Endocrinology TDM Thyroid Function Tumor Markers/Oncology Other Veterinary

11 Current IMMULITE Systems Test Menu Real Choice. Over 95 assays plus a menu of over 465 essential specific allergens and allergen panels. Not all assays available on all platforms or all countries. (See Siemens website for current menu at Adrenal/Pituitary Cardiac Biomarkers Infectious Disease TDM Tumor Markers Under Development ACTH CK-MB EBV-EBNA IgG Carbamazepine AFP Anti-CCP D-Dimer EBV-VCA IgG Cortisol Digitoxin BR-MA (CA15-3) Celiac Disease Markers Myoglobin EBV-VCA IgM Digoxin CEA (Anti-Gliadin IgA, NT-proBNP* Syphilis Phenobarbital GI-MA (CA19-9)* Anti-Gliadin IgG) Allergy Troponin I Phenytoin OM-MA (CA125) CMV Antibody Avidity 3gAllergy Specific IgE Theophylline PAP* Procalcitonin Inflammation Markers (Quantitative) Allergen-Specific IgG* (See Allergen Menu) Allergen Specific IgG4* (See Allergen Menu) AlaTOP Allergy Screen ECP* Total IgE Anemia EPO Ferritin Folic Acid Homocysteine Vitamin B12 Autoimmune Anti-tTG IgA Bone Metabolism Calcitonin Osteocalcin* Intact PTH Pyrilinks -D Page 11 Diabetes Urinary Albumin C-Peptide Insulin Growth hgh IGF-I IGFBP-3 Infectious Disease CMV IgG CMV IgM* H. pylori IgG Anti-HBc Anti-HBc IgM HAV Total* HAV IgM* HBsAg HBsAg Confirmatory Anti-HBs Herpes I & II IgG Rubella Quantitative IgG Rubella IgM Toxoplasma Quantitative IgG Toxoplasma IgM Toxoplasma IgM mu-capture High Sensitivity CRP IL-1β IL2R IL-6 IL-8 IL-10 LBP* (Lipopolysaccharide Binding Protein) TNFα Reproductive Endocrinology AFP (NTD) Androstenedione DHEA-SO 4 Estradiol Unconjugated Estriol FSH HCG (Total HCG) Free Beta HCG LH PAPP-A* Progesterone Prolactin SHBG Total Testosterone Tobramycin Valproic Acid Vancomycin Thyroid Function Free T3 Total T3 Free T4 Total T4 TBG Thyroglobulin Anti-TG Ab Anti-TPO Ab Thyroid Uptake Rapid TSH Third Generation TSH PSA Free PSA Third Generation PSA STAT Assays: CK-MB HCG (Total HCG) Intact PTH (Turbo) Myoglobin STAT Troponin I NT-proBNP* D-Dimer Veterinary Canine Total T4 Canine TSH Canine TLI Other Analytes Beta-2 Microglobulin Gastrin Nicotine Metabolite* Measles IgG & IgM Mumps IgG & IgM Lyme Screen TSI Vitamin D * Available outside the US Does not bear the CE Mark

12 (TIP) Position Tip Position Page 12

13 TIP SENSOR LOCATIONS INCUBATOR Incubator Belt 2 TIP Pipetting Position Belt Transfer TIP Wash 1 TIP Wash 2 TIP Inlet TIP Page 13

14 OFFSET SENSOR LOCATIONS- INCUBATOR Incubator Belt 2 Incubator Belt 2 Home Transfer Offset Incubator Wash 1 & Pipettor Offset Incubator Belt 2 Wash 2 Offset Incubator Inlet Offset Incubator Belt 1 Home Incubator Belt 1 Transfer Offset Page 14

15 TIP SENSOR LOCATIONS - LUMINOMETER PMT Attenuator Motor Luminometer TIP Wash 1 Luminometer TIP Wash 2 Exit Transfer Motor PMT Transfer Motor Page 15

16 OFFSET SENSOR LOCATIONS LUMINOMETER Luminometer Home Luminometer Wash 1, Wash 2, Substrate, PMT Transfer Offset Page 16

17 Questions? Thank you for your time today. Page 17

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