MEMORANDUM. These reference ranges are effective immediately but sample requirements remain unchanged currently.

Transcription

1 MEMORANDUM Originating Department Chemical Pathology Issued By: Issued To: Subject: Details: Dr. Shari Srinivasan All Laboratory Service Users Change in Chemical Pathology Analysers Dear Colleague, As you may be aware, the Chemical Pathology Laboratory in Beaumont Hospital has introduced new analysers for routine chemistry and immunoassay testing. The table on the following pages provides a summary of changes to reporting and units. Significant changes are highlighted in bold text. New reference and interpretative comments (when required) will be appended to all test reports. These reference are effective immediately but sample requirements remain unchanged currently. As time progresses, changes will be required to this table which will be updated in the Current Roche Reference Ranges document available in the following locations: Chemical Pathology Internet Page: Hospital Intranet Page: The user manuals for the department will be updated with this information in due course. As a result of this change in technology, please be aware that the department is no longer accredited for the tests listed above. However, internal validation of all assays has verified the clinical acceptability of these tests and accreditation will be sought for them at the next assessment by the Irish National Accreditation Board. Please contact the laboratory on (852) 8391 with any clinical queries that may arise. Kind regards, Dr. Shari Srinivasan Consultant Chemical Pathologist Mr. Peter O Leary Laboratory Manager NOTE: All memos issued from the Clinical Directorate of Laboratory Medicine must be recorded as active documents on Q-Pulse Page 1 of 6

2 ROUTINE CHEMISTRY AAT g/l ACE IU/L ALBUMIN g/l ALK U/L F: M: ALT U/L F: 0-35 M: 0-50 F: 0-33 M: 0-41 AMYLASE U/L AST U/L F: 0-35 M: 0-50 F: 0-32 M: 0-40 (VITAMIN) B12 ng/l % positive bias B2MICROGLOBULIN mg/l BILIRUBIN TOTAL μmol/l BILIRUBIN DIRECT μmol/l CALCIUM mmol/l CERULOPLASMIN g/l F: M: CHOLESTEROL mmol/l CK U/L F: M: F: M: CL mmol/l CREATININE μmol/l F: F: % positive bias M: M: CRP mg/l % negative bias at high levels CSF PROTEIN mg/dl Page 2 of 6

3 CSF GLUCOSE mmol/l 60% of serum FE (IRON) μmol/l F: M: FERRITIN ng/ml F: F: % negative bias M: M: FOLATE μg/l GGT U/L F: 0-38 M: 0 55 F < 40 M < 60 GLUCOSE (fasting) mmol/l HDL mmol/l >1.0 IGA g/l IGG g/l IGM g/l K mmol/l LDH U/L F: M: % negative bias LDL CHOLESTEROL mmol/l 0 3 <3.0 Calculated Value MG mmol/l NA mmol/l NT PRO BNP pg/ml Age related Age related No change NON HDLC mmol/l <3.8 <3.8 PO4 mmol/l PROTEIN g/l TCO2 mmol/l Page 3 of 6

4 TROPONIN <0.04 ug/l <14ng/L *Change of assay to hstnt * *New reporting units* *Do NOT compare old and new values* TRANSFERRIN mg/dl TRIGLYCERIDE mmol/l (non-fasting) (fasting) URATE μmol/l F: M: F: M: UREA mmol/l ENDOCRINOLOGY ACTH pg/ml No change CORTISOL (AM) nmol/l DHEAS μmol/l Age and gender related ESTRADIOL pmol/l Follicular: Ovulation: Luteal: Postmenopause: <147 MALE: <173 Age and gender related Follicular: Ovulation: Luteal: Postmenopause: < MALE: : FT4 pmol/l FSH miu/l Follicular: 1-10 Ovulation: 4-23 Luteal:1-8 Postmenopause: MALE: 1 12 MALE: Follicular: Ovulation: Luteal: Postmenopause: No change INSULIN miu/l No change s Page 4 of 6

5 LH miu/l Follicular: 2-12 Ovulation: Luteal:1-13 MALE: 1 9 PROGESTERONE nmol/l Follicular: Luteal: Follicular: Ovulation: Luteal: Postmenopause: MALE: Follicular: Ovulation: Luteal: Postmenopause: < Page 5 of 6 MALE: < PROLACTIN miu/l F: F: M: M: PTH pg/ml No change SHBG nmol/l Age and gender related Age and gender related No change OSTERONE nmol/l Age and gender related Age and gender related No change TSH miu/l THERAPEUTIC DRUG MONITORING CARBAMAZEPINE mg/l DIGOXIN μg/l ETHANOL mg% <10 <10 GENTAMYCIN μg/ml Trough: Peak: 6-10 LITHIUM mmol/l PARACETAMOL mg/l <10 <5 See Nomogram PHENOBARBITONE mg/l No change PHENYTOIN mg/l No change

6 SALICYLATE mg/l <15 <10 THEOPHYLLINE mg/l No change VALPROATE mg/l No change VANCOMYCIN μg/ml No change Page 6 of 6