Programme Malaria integration of new tools for zero deaths and elimination Monday 20 Wednesday 22 February 2012 WP1141

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1 Programme Malaria integration of new tools for zero deaths and elimination Monday 20 Wednesday 22 February 2012 WP1141 Around 40% of the world s population are at risk from malaria and there are approximately 300 million cases of acute malaria each year. Around 90% of these cases occur in Sub Saharan Africa, where the World Bank estimates that malaria costs more than $12 billion a year in healthcare and lost productivity approximately the same amount that is provided annually to the region in aid. This round-table meeting at Wilton Park will follow-up on the Wilton Park conference Malaria: Getting to Zero (held in April 2009) and will identify progress and next steps looking to the next five years in moving from the control to the elimination and eradication of malaria. As part of these next steps, and looking to the next five years, the workshop will discuss new tools, including the potential for a vaccine, update on trials of the candidate RTS,S vaccine, and progress with the development of epidemiological and economic models which will guide the use of any vaccine. It is anticipated that this meeting in early 2012 might be followed by a further meeting in 2013 to focus exclusively on global policy and planning needed for the implementation and roll-out of a successful vaccine. In association with The Global Health Group, University of California, San Francisco (UCSF), GlaxoSmithKline, Medicines for Malaria Venture, Novartis, PATH Malaria Vaccine Initiative and Vestergaard Frandsen Monday 20 February Participants arrive and buffet lunch available Welcome and introduction Robin Hart Director of Programmes, Wilton Park, Steyning Richard Feachem Director, The Global Health Group, Global Health Sciences, University of California, San Francisco

2 Moving from control, to elimination and eradication of malaria: what progress? To include: update since WP conference on Malaria: Getting to Zero in What progress of existing tools in control, elimination and eradication? What are the recent technical and scientific advances? What challenges remain? How would any successful vaccine change the game? Highlighting considerations in the preparations for any introduction of a vaccine. What leadership is needed? Chair: Robin Hart, Director of Programmes, Wilton Park Malaria Control: Robert Newman Director, Global Malaria Programme, World Health Organisation, Geneva Malaria Elimination: Richard Feachem Director, The Global Health Group, Global Health Sciences, University of California, San Francisco Photograph and tea/coffee Country perspectives: diagnosis and prognosis 1900 Drinks reception What do countries anticipate will change over the next few years? What will malaria look like in 2020? What worries (eg resistance to insecticides or ACTs?)? What opportunities? What planning assumptions are being made? What access and equity issues are being addressed? How countries are organising themselves to tackle this and how will this change? Chair: Bruno Moonen, Director, Malaria Control Team, Clinton Health Access Initiative (CHAI), Nairobi C O Onyebuchi Chukwu Minister of Health, Federal Ministry of Health, Abuja Richard Nchabi Kamwi Minister of Health and Social Services, Ministry of Health and Social Services, Windhoek Evelize Fresta Vice-Minister of Health, Ministry of Health, Luanda 1930 Dinner hosted by Richard Burge, Chief Executive, Wilton Park After dinner speaker Stephen O Brien Parliamentary Under Secretary of State for International Development, Department for International Development, London Tuesday 21 February Breakfast

3 New tools in the fight against malaria Part A: Drugs, vector control, others Tea/coffee Tools in the fight against malaria: progress in developments. New drugs, improved diagnostics, new insecticides, better surveillance, and other technologies. Chair: Rose Leke, Head, Department of Microbiology, Immunology and Haematology, University of Yaounde, Yaounde David Reddy Chief Executive Officer, Medicines for Malaria Venture, Geneva Robert Sloss Public Health Pesticides Portfolio Manager, The Innovative Vector Control Consortium (IVCC), Liverpool School of Tropical Medicine, Liverpool Christian Lengeler Head, Health Interventions Unit, Swiss Tropical and Public Health Institute, Basel Part B: RTS, S vaccine candidate: what progress? Lunch Clinical Update on the candidate vaccine RTS,S; the science, trials and timetable of ongoing vaccine development. What contribution would a vaccine make towards control and elimination? What more information would malaria affected countries need? Chair: Jimmy Whitworth, Head of International Activities, Wellcome Trust, London Mary Hamel Medical Epidemiologist and Senior Technical Adviser, Center for Disease Control and Prevention (CDC), Washington DC Patricia Njuguna Clinical Researcher; Paediatrician, KEMRI Wellcome Trust Research Programme, Kilifi Garden tour (optional; weather permitting) Part B: RTS, S vaccine candidate: what progress? Tea/coffee Health Economics What are the health economics models suggesting in relation to candidate vaccine RTS,S.? How cost effective? What contribution would a vaccine make towards control? What more information would malaria affected countries need? What models are needed to assist stakeholders in making choices about a vaccine? Chair: Sunil Mehra, Executive Director, Malaria Consortium, London Priscillia Hunt Senior Analyst, RAND Europe, Brussels Christophe Sauboin Senior Manager, Health Economics, GlaxoSmithKline Biologicals, Wavre

4 Integrating new tools into country malaria intervention programmes Plenary introduction followed by discussion in smaller groups Chair: Steven Phillips, Medical Director, Global Issues and Projects, Exxon Mobil Corporation Groups might discuss: 1. How new interventions becoming available in the malaria tool box might be adapted and utilised in county malaria programmes. 2. What health outcomes data would be useful to support possible policy formulation at global (WHO) and national (EPI; Expanded Programme on Immunisation/NMCP; National Malaria Control Programme) levels? 3. What additional data/information would be required to effectively integrate the new toolbox and design an optimal malaria programme? 4. Perceptions of the role of a vaccine in a programme; ensuring solutions work for communities. Discussion group leaders: 1900 Drinks reception Jason Peat Senior Public Health Officer, International Federation of Red Cross (IFRC), Geneva Antoinette Ba-Nguz Senior Programme Officer for Africa, Policy and Access, PATH Malaria Vaccine Initiative (MVI), Nairobi Constance Bart-Plange National Malaria Programme Manager, Malaria Control Programme, Ghana Health Service, Accra Doreen Ali Malaria Control Programme Manager, Ministry of Health, Lilongwe 1930 Dinner Wednesday 22 February Breakfast Integrating new tools into country malaria intervention programmes Feedback from the discussion groups followed by plenary discussion Chair: Steven Phillips, Medical Director, Global Issues and Projects, Exxon Mobil Corporation, Fairfax Financing for malaria How do we ensure adequate financing for continued progress against malaria? How will new interventions be financed? Would a malaria vaccine be financed by the Global Fund or GAVI or both? How can domestic resources for malaria be optimised? Chair: Andrew Jack, Pharmaceuticals Correspondent, Financial Times, London Alan Court Senior Adviser to the Secretary General s Special Envoy for Malaria, United Nations, New York

5 Tea/coffee Sanne Fournier-Wendes Global Partnership Manager, Vestergaard Frandsen, Lausanne The next decade: what do we need to do differently? 1230 Lunch Discussion chaired by Richard Feachem, Director, The Global Health Group, Global Health Sciences, University of California, San Francisco Thomas Teuscher Deputy Executive Director ai, Roll Back Malaria Partnership (RBM), Geneva Roy Anderson Director, London Centre for Neglected Tropical Diseases, School of Public Health, Faculty of Medicine, Imperial College London, London 1400 Participants depart

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