FOCUS ON NEUROENDOCRINE TUMORS 7 TH ANNUAL. Friday, April 13, am 2 pm. REGISTER ONLINE AT PennMedicine.org/Abramson/NETs

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1 DEDICATED TO CURING NEUROENDOCRINE CANCER 7 TH ANNUAL FOCUS ON NEUROENDOCRINE TUMORS A PATIENT AND CAREGIVER PROGRAM Friday, April 13, am 2 pm REGISTER ONLINE AT PennMedicine.org/Abramson/NETs Attend in Person or View Livestream OPEN TO THE PUBLIC Law Auditorium // Jordan Medical Education Center // Perelman Center for Advanced Medicine 3400 Civic Center Boulevard // Philadelphia, PA 19104

2 7 TH ANNUAL FOCUS ON NEUROENDOCRINE TUMORS A PATIENT AND CAREGIVER PROGRAM DATE Friday, April 13, 2018 TIME 8:00 am 2:00 pm LOCATION Law Auditorium Jordan Medical Education Center Perelman Center for Advanced Medicine 3400 Civic Center Boulevard Philadelphia, PA FREE Parking! FOLLOW US #PhillyNETS WHO SHOULD ATTEND: Newly diagnosed, currently in treatment or long-term survivor of: Gastrointestinal Tract NETs including: Pancreatic NETs (hereditary or sporadic) Zollinger-Ellison syndrome (gastrinomas) Insulinomas Alimentary tract NETs (foregut, midgut or hindgut) Functional (carcinoid syndrome) Non-functional Bronchial, Thymic and Carcinoid in other locations Pheochromocytomas and Paragangliomas including hereditary and sporadic forms Hereditary Syndromes associated with Neuroendocrine Tumors If you are a family member or caregiver REGISTRATION To register or for more information, call PENN (7366) or visit PennMedicine.org/Abramson/NETs. Parking will be validated Parking information can be found at PennMedicine.org. $25 suggested donation (non-tax deductible) to support the Focus On Neuroendocrine Tumors Conference. Cash, check, money order or credit card accepted the day of the conference.

3 AGENDA 8:00 am Check In Continental Breakfast, Visit Exhibits and Experts 8:40 am Welcome and Opening Remarks Debbie L. Cohen, MD, Conference Co-Chair Joseph R. Carver, MD, Chief of Staff, Abramson Cancer Center Elyse Gellerman, MHS, Chief Executive Officer Neuroendocrine Tumor Research Foundation 8:45 am News from the Neuroendocrine Tumor Research Foundation Elyse Gellerman, MHS, Chief Executive Officer Neuroendocrine Tumor Research Foundation 9:05 am News from the Abramson Cancer Center Andrew Bellet, Major Gifts Officer, Abramson Cancer Center MORNING SESSION 9:15 am Management of NETs Overview David C. Metz, MD, Gastroenterology Debbie L. Cohen, MD, Nephrology 9:45 am Research and Clinical Update from the Penn NET Center Promising Studies including Car T and Pheo/Para Bryson W. Katona, MD, PhD, Gastroenterology Heather Wachtel, MD, Endocrine and Oncologic Surgery 10:05 am Interventional Approaches for NETs Michael C. Soulen, MD, Interventional Radiology 10:25am Surgery for NETs Heather Wachtel, MD, Endocrine and Oncologic Surgery Robert E. Roses, MD, Endocrine and Oncologic Surgery 10:50 am KEYNOTE: Theranostics for Neuroendocrine Tumors Lisa Bodei, MD, PhD, Molecular Imaging and Targeted Radionuclide Therapy 11:30 am Lunch CONFERENCE CO-CHAIRS: David C. Metz, MD, Professor of Medicine, Gastroenterology, Co-Director, Neuroendocrine Tumor Center Debbie L. Cohen, MD, Associate Professor of Medicine, Director of Clinical Hypertension Programs, Co-director of Neuroendocrine Tumor Program Elyse Gellerman, MHS, Chief Executive Officer, Neuroendocrine Tumor Research Foundation Foundation

4 AFTERNOON GENERAL SESSION 12:15 pm Multidisciplinary Team Approach for Managing NETs MODERATORS David C. Metz, MD and Debbie L. Cohen, MD PANEL MEMBERS Lisa Bodei, MD, PhD, Molecular Imaging and Targeted Radionuclide Therapy Diann Boyd, BSN, RN, OCN, NET Navigation Jason Brant, MD, Otorhinolaryngology Joseph R. Carver, MD, Cardiology Keith A. Cengel, MD, PhD, Radiation Oncology Nevena Damjanov, MD, Medical Oncology Anna Jung, PharmD, BCPS, GI Pharmacist Julia N. Kharlip, MD, Endocrinology John C. Kucharczuk, MD, Thoracic Surgery Katherine L. Nathanson, MD, Genetics Daniel A. Pryma, MD, Radiology, Nuclear Medicine Robert E. Roses, MD, Surgery, Endocrine &Oncologic Surgery Stuti Shroff, MD, PhD, Pathology & Laboratory Medicine Michael C. Soulen, MD, Interventional Radiology Ursina R. Teitelbaum, MD, Medical Oncology/Palliative Care Heather Wachtel, MD, Endocrine and Oncologic Surgery 1:45 pm Patient Power It Take Guts MODERATORS Neal Niznan, MSW, LCSW and Bonnie Bennett, BSN, RN 2:00 pm Conference Closing EXHIBIT HALL Visit our experts in Survivorship and integrative Therapies Integrative Therapies Surgery Nurse Coping with Emotions Giving Back Good Shepherd Penn Partners - Penn Therapy and Fitness Optional Managing GI Symptoms Managing Symptoms - Liver Directed Therapy Managing Symptoms - Chemotherapy Nutrition Nurse Navigation Palliative Care

5 KEYNOTE SPEAKER Lisa Bodei, MD, PhD Director of Targeted Radionuclide Therapy Molecular Imaging and Therapy Service Department of Radiology Dr. Bodei is a nuclear medicine physician who has extensive experience and broad expertise in therapeutic and diagnostic applications of nuclear medicine in oncology. Her clinical and research includes combining the therapeutic and diagnostic components of nuclear medicine, which is referred to as theranostics. From the therapeutic perspective, her special expertise is in the development of peptide receptor radionuclide therapy (PRRT) of gut and lung neuroendocrine tumors, including special investigational and molecular translational analyses to facilitate their diagnosis and therapy. ABOUT Neuroendocrine Tumor Research Foundation NETRF.org The mission of the Neuroendocrine Tumor Research Foundation is to fund research to discover cures and more effective treatments for carcinoid, pancreatic, and related neuroendocrine cancers. Abramson Cancer Center PennMedicine.org/Abramson At the Abramson Cancer Center our mission is to reduce the burden of cancer throughout our region, the nation and the world through the development of an integrated program of laboratory, clinical and population based research. The Abramson Cancer Center has been continuously designated as a Comprehensive Cancer Center by the National Cancer Institute (NCI) since One of only 45 such Centers in the country. The Abramson Cancer Center was rated EXCEPTIONAL by the NCI at our last competitive review the highest possible rating a Center can receive. The Focus on Neuroendocrine Tumors Conference is being held in collaboration with the Penn Medicine Development Office and the NET Research Foundation. Attendees will receive communication from the PENN Medicine Development Office regarding their research and programs. Participation in this conference is optional and patient privacy has been maintained. If you would prefer not to receive development materials, we will make reasonable efforts to honor such a request. Please send a written request with your name, and address to Tricia Bruning, Abramson Cancer Center Development Office, 3535 Market Street, Suite 750, Philadelphia, PA and to NET Research Foundation, 321 Columbus Avenue, Suite 5R, Boston, MA

6 3600 Market Street Suite 240 Philadelphia, PA TH ANNUAL FOCUS ON NEUROENDOCRINE TUMORS A PATIENT AND CAREGIVER PROGRAM Friday, April 13, am 2 pm Comprehensive Cancer Center A Cancer Center Designated by the National Cancer Institute Non-profit U.S. Postage PAID Permit No Phila, PA 19176

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