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1 COURSE MODULE Program Title B. Pharmacy Department Pharmacognosy Course Title Pharmacognosy II
2 1. NAME OF INSTITUTION : Y. B. CHAVAN COLLEGE OF PHARMACY, AURANGABAD 2. AFFILIATED UNIVERSITY : DR. BABASAHEB AMBEDKAR MARATHWADA UNIVERSITY, AURANGABAD 3. DEPARTMENT : Pharmacognosy 4. PROGRAM TITLE : B. PHARM 4.1. Program Outcomes (PO): PO 01: Pharmacy Knowledge: Possess knowledge and comprehension of the core and basic knowledge associated with the profession of pharmacy, including biomedical sciences; pharmaceutical sciences; behavioral, social, and administrative pharmacy sciences; and manufacturing practices. PO 02: Planning Abilities: Demonstrate effective planning abilities including time management, resource management, delegation skills and organizational skills. Develop and implement plans and organize work to meet deadlines. PO 03: Problem analysis: Utilize the principles of scientific enquiry, thinking analytically, clearly and critically, while solving problems and making decisions during daily practice. Find, analyze, evaluate and apply information systematically and shall make defensible decisions. PO 04: Modern tool usage: Learn, select, and apply appropriate methods and procedures, resources, and modern pharmacy-related computing tools with an understanding of the limitations. PO 05: Leadership skills: Understand and consider the human reaction to change, motivation issues, leadership and team-building when planning changes required for fulfillment of practice, professional and societal responsibilities. Assume participatory roles as responsible citizens or leadership roles when appropriate to facilitate improvement in health and wellbeing. PO 06: Professional Identity: Understand, analyze and communicate the value of their professional roles in society (e.g. health care professionals, promoters of health, educators, managers, employers, employees). PO 07: Pharmaceutical Ethics: Honour personal values and apply ethical principles in professional and social contexts. Demonstrate behavior that recognizes cultural and personal variability in values, communication and lifestyles. Use ethical frameworks; apply ethical principles while making decisions and take responsibility for the outcomes associated with the decisions.
3 PO 08: Communication: Communicate effectively with the pharmacy community and with society at large, such as, being able to comprehend and write effective reports, make effective presentations and documentation, and give and receive clear instructions. PO 09: The Pharmacist and society: Apply reasoning informed by the contextual knowledge to assess societal, health, safety and legal issues and the consequent responsibilities relevant to the professional pharmacy practice. PO 10: Environment and sustainability: Understand the impact of the professional pharmacy solutions in societal and environmental contexts, and demonstrate the knowledge of, and need for sustainable development. PO 11: Life-long learning: Recognize the need for, and have the preparation and ability to engage in independent and life-long learning in the broadest context of technological change. Selfassess and use feedback effectively from others to identify learning needs and to satisfy these needs on an ongoing basis. 5. COURSE SPECIFICATION : 5.1. Course Identification and General Information a. Course Title: Pharmacognosy II b. Course Number/ Code c. Credit Hours e. Study level/ semester at which this course is offered f. Pre-requisite g. Co-requisite 440 Theory Practical Total Semester IV 10+2 Syllabus Basics of Pharmacognosy I (120,) Taxonomy h. Language of teaching the course English i. Prepared by Dr. Subur Khan, Mrs. Reshma Toshniwal j. Approved by Dr. Abubakar Bawazir 5.2. Course Description: 5.3. Course Objectives
4 To develop the knowledge of our alternative system of medicine. To develop knowledge of different traditional drugs. To develop the knowledge base regarding source, active constituents and uses of crude drugs. To develop the ability about the understanding of performing chemical tests the identity and quality of natural products 5.4. Course Outcomes (CO):(around 5 to 8) (e.g. CO101.1 (CO - course code, 101 subject code as per syllabus, &.1 is first CO) Code Course outcome CO Ability to explain the origin of drugs from natural sources. CO CO CO CO CO Ability to explain the role of natural products as the source of many drugs and pharmaceutical ingredients Identify some drugs available in the healthcare system that are obtained or sourced from natural products. Discuss the processes of standardization of natural products following WHO and other existing guidelines Attain Knowledge of the important natural products, their origin, properties and biological activity Identify the common adulterations and substitutions Alignment of PO to CO: (PO: Program Outcome; CO: Course Outcome) Course code (CO) Program Outcome (PO) PO1 PO2 PO3 PO4 PO5 PO6 PO7 PO8 PO9 PO10 PO11 CO H M CO H - M S - - M - M M M CO H - M S M M M CO H - M S - - M - M M M CO H - M S M M M CO H - M S - - M - M M M Correlation levels H, M or S as defined below: S: Slight (Low); M: Moderate (Medium); H: Substantial (High); If there is no correlation, put Teaching and Assessment Methods for achieving learning outcome: Teaching Strategies /methods used Methods of Assessment
5 Lectures Group Discussions Demonstrations Problem Solving Sessions Assignments Oral Presentations Written Examinations Discussions and tutorials 6. COURSE CONTENTS: 6.1. Theoretical Aspect: Order Topic list/units Subtopics list 1 Alternative various systems of medicine practiced in India viz: Ayurveda, Unani, Homeopathic and Siddha. Number Contact of Weeks Hours The holistic concept of drug administration in traditional systems of medicine. Introduction to Ayurvedic preparations like Arishtas, Asvas, Gutikas, Tailas, Chumas, Lehyas and Bhasmas
6 3 Studies of traditional drugs,. common vernacular names, botanical sources, morphology, chemical nature of chief constituents, pharmacology, categories and common uses and marketed formulations of following indigenous drugs: Amla, Kantkari, Satavari, Tylophora, Bhilawa, Kalijiri, Bach, Rasna, Punamava, Chitrack, Apamarg, Gokhru, Shankhapushpi, Brahmi, Ashoka, Methi, Lahsun, Palash, Guggal, Gymnema, Shilajit, Nagarmotha, Neem, Manjistha, Gulvel, Pippali and Chirata An introduction to metabolites Primary and Secondary A detailed study of various methods of extraction and isolation of phytopharmaceuticals infusion, decoction, digestion, maceration, percolation, successive solvent extraction, supercritical fluid extraction, steam distillation, had space techniques, sepbox, selection of suitable extraction process Phytochemical Screening Screening of alkaloids, saponins, cardenolides and bufadienolides, flavonoids and leucoanthocyanidins, tannins and polyphenols, anthraquinones, cynogenetic glycosides, amino acids in plant extracts Application different methods ochromatography and spectroscopy in plant drug analysis Quality control of herbal drugs WHO, AYUSH and Pharmacopoeial guidelines-extractive values, ash values. Determination of heavy metals, insecticides, pesticides and microbial load in herbal preparations 0.5 2
7 9 Quantitative microscopy: Definition and determination of stomatal index, stomatal number, palisade ratio, vein islet number, vein termination number, lycopodium spore method Glycosides : Definition, Classification, General properties, General method of isolation of Glycosides. Study of Source, Morphology, chemical constituents, chemical test, adultrants, sustituents and uses of following drugs a. cardiac glycosides: Digitalis, strophanthus, squill. b. anthracene glycosides: Senna, Aloe, Rhubarb, Cascara c. Saponin glycosides: Dioscorea, asparagus, safed musali, liquorice, Brahmi, Ginseng. d. cyanogenetic glycosides: Bitter almond e. Isothiocyanates glycosides: Black mustard f. Coumarin glycosides: Psroalea, g. Flavonoid glycosides: Silymarin. h. Others: Ashwanghandha, kalmegh, picrorhiza 11 Proteins & Enzymes: Biological sources, preparation, characters and uses of: Gelatin, Collagen, diastase, papain bromalain, pancreatin, urokinase, pepsin, trypsin, pencillinase, hyaluronidase and stryptokinase Lipids Bees wax, Castor oil, Cocoa butter, Cod~liver oil, Hydnocarpus oil, Kokum butter, Lard, Linseed oil, Rice, Bran oil, Shark liver oil and Wool fat Animal products: Biological sources, chemical constituents, adulterants and uses of: Shellac, cochineal, cantherides, honey, and musk Natural toxins Study of allergens, hallucinogens, narcotics, toxic mushrooms and afalotoxin Marine Drugs:. Introduction, importance, classification of following class of drugs: Cytotoxic and antineoplastic agents, Cardiovascular drugs, Marine toxins, Antimicrobial drugs, and Antibiotic substances 0.5 2
8 6.2. Practical Aspect (If Any): Number of Contact Order Tasks/Experiments Weeks Hours * 6.3. Assignments/Tutorials: Tutorials given on topics of syllabus and assignments were given as questions on the respective chapters. 7. SCHEDULE OF ASSESSMENT TASKS DURING THE SEMESTER: Sr. No. Assessment Method Week due Marks Proportion of Final Assessment 1. Sessional ( Internal Theory exam) 20 20% 2. Final exam (theory) As per University at 80 80% end of course Total % 8. STUDENT SUPPORT: Office Hours/Week Two hours minimum Other Procedures , etc 9. TEACHER S AVAILABILITY FOR STUDENT SUPPORT: Days Monday Tuesday Wednesday Thursday Friday Saturday Time 4-5pm 4-5pm 4-5pm 4-5pm 4-5pm 4-5pm 10. LEARNING RESOURCES: Sr. No. Title of Learning Material Details 1 Text books 1.Wallis T. E., Textbook of Pharmacognosy, CBS, Delhi 2.Jean Bruneton., Pharmacognosy and Phytochemistry, Lavosier Publisher U.K. 3.Wagner and Bladt, Plant Drug analysis, Springer U.K.
9 4.V. E. Tylor, L. R. Brady and S. B. Robbers, Pharmacognosy, K.M. Varghese Co. Bombay. 5.Indian Herbal Pharmacopoiea, K. M. Varghese Co.Bombay 2 Essential references (as per syllabus) 1. C.K. Kokate, S.B. Gokhale, Nirali Publication 2. Vinod Rangari, Career publication 3 Reference material Book 4 E-materials and websites Powerpoint presentations 5 Other learning material Notes 11. FACILITIES REQUIRED: Sr. No. Particular of Facility Required 01 Lecture Rooms (capacity for 60 students) 02 Laboratory (capacity for 20 students) 03 Computing resources: P-IV-PCs with recent hardware/ utilization of open source and licensed application software 04 Other resources: Appropriate laboratory tools, Chemicals, Glass ware, Apparatus, Instrumentation 12. COURSE IMPROVEMENT PROCESSES: Strategies for obtaining student feedback on effectiveness of teaching: Course delivery evaluation by students using: questionnaires Questionnaire forms and online Other strategies for evaluation of teaching by the instructor or by the department: Periodic review by Academic Planning & Monitoring Committee and departmental review committee, Observations and assistance of colleagues, External assessments by advisors/ examiners and auditors Process for improvement of teaching: Use of ICT tools, teaching aids, Simultaneous practical orientation and theory classes (SPOT), Adoption of reflective teaching Describe the planning procedures for periodically reviewing of course effectiveness and planning for improvement:
10 Periodic review by departmental review committee, Review of course delivery and outcome through assessment and feedback from all stake holders Course development plans: Provide inputs for course improvement and update to University Course development Committees (Board of Studies) 13. INFORMATION ABOUT FACULTY MEMBER RESPONSIBLE FOR THE COURSE: Name Dr. Subur Khan, Mrs. Reshma Toshniwal Location Pharm Analysis Lab.(second floor), Pharmaceutics Lab (second floor) Contact Detail ( & Cell No.) , Office Hours 10.00am-5.00pm
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