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1 Program Agenda Tuesday, January 26, :00 PM to 1:00 PM Eastern Time 11:00 AM to 12:00 PM Central Time 10:00 AM to 11:00 AM Mountain Time 9:00 AM to 10:00 AM Pacific Time 11:45 AM ET Registrants Join the Program Dial-in: (877) Log-in: 12:00 12:05 PM ET Welcome and Introduction Stephanie Paul Vice President Development and Marketing American Parkinson Disease Association Staten Island, NY 12:05 12:35 PM ET Presentation David G. Standaert, MD, PhD John N. Whitaker Professor and Chair of Neurology The University of Alabama Birmingham School of Medicine Birmingham, AL Chair, APDA Scientific Advisory Board 12:35 12:55 PM ET Questions and Answers with Dr. Standaert 12:55 1:00 PM ET Closing Remarks Stephanie Paul 1:00 PM ET Adjournment
2 Biography David G. Standaert, MD, PhD John N. Whitaker Professor and Chair of Neurology The University of Alabama Birmingham School of Medicine Birmingham, AL Chair, APDA Scientific Advisory Board Dr. Standaert graduated from Harvard College in He received his MD and PhD degrees from Washington University in St. Louis. He completed a one-year internship in Medicine followed by a three-year Neurology residency at the University of Pennsylvania. He was appointed a Howard Hughes Medical Institute Physician Research Fellow, and completed a three-year research and clinical fellowship in Neurology (Movement Disorders) at Massachusetts General Hospital (MGH) in He subsequently joined the faculty at Harvard Medical School and MGH, where he served as Director of the MGH/MIT Udall Center of Excellence in PD Research. Dr. Standaert relocated to the University of Alabama at Birmingham (UAB) in July of 2006, and is now the John N. Whitaker Professor and Chair of the Department of Neurology. He serves as Director of the Division of Movement Disorders, the Director of the American Parkinson Disease Association (APDA) Advanced Center for Parkinson Research at UAB, and Director of the UAB Bachmann-Strauss Center for Dystonia and Parkinson Disease. He sees patients in a weekly clinic and oversees many clinical trials for new treatments of Parkinson's Disease. He is Chair of the Scientific Advisory Board of the American Parkinson Disease Association, a member of the Scientific Advisory Board of the Michael J. Fox Foundation for Parkinson Research, an Associate Editor of the Movement Disorders Journal, and a member of the Board of Directors of the American Neurological Association. He is a member of the Board of Directors of the UAB Health System, and Chair of the UAB Health Services Foundation Advisory Committee. Dr. Standaert s laboratory works on understanding both the root causes of Parkinson s Disease as well as the origin of the disabling symptoms that appear after long-term treatment of the disease.
3 Evaluation Form Your feedback is important to us. It is used to help design and fund future programs. Please return the completed evaluation form at the end of the program or complete it online at Thank you for your assistance. 1) How would you rate the program objectives, content, and accessibility? The program met its objectives The level of material presented was appropriate The program was easy to access Excellent Good Fair Poor ) Please rate the presentation and discussion: Parkinson s Disease Spotlight on Treatment Advances David G. Standaert, MD, PhD John N. Whitaker Professor and Chair of Neurology The University of Alabama Birmingham School of Medicine Birmingham, AL Chair, APDA Scientific Advisory Board Excellent Good Fair Poor Content Format Discussion ) How did you learn about this program? invitation APDA website Twitter Facebook APDA local chapter Other 4) What influenced your decision to attend our program? Content Format Program Faculty Other January 26, 2016 Page 1 of 2
4 5) I am a: Person with Parkinson s Disease Spouse Family Member Care Partner Friend Researcher Nurse Physician Other 6) Do you think that this program was valuable? YES NO 7) What is your preferred method to receive Parkinson s Disease information? (Indicate all that apply.) Telephone Education Programs Web Education Programs Live Seminars Online/Internet Print Materials Healthcare Provider CD-Roms/DVD Other 8) Will the information presented today help influence you to modify or change any aspect of your treatment decisions? YES NO 9) What recommendations do you have to improve this program for the future? 10) Would you attend another program similar to this? YES NO 11) What topics would you like to see presented in future Parkinson s Disease-specific programs? Name: Mail this completed form to: AOI Communications, L.P., 1 East Uwchlan Ave., Suite 408, Exton, PA January 26, 2016 Page 2 of 2
5 Basic Information About PARKINSON S DISEASE American Parkinson Disease Association
6 ABOUT PARKINSON S DISEASE Parkinson s disease (PD) is a progressive neurological condition that affects more than one million people in the United States. Approximately 60,000 people are newly diagnosed each year. Onset commonly occurs after age 60; however, up to 10% of individuals with PD will receive an earlier diagnosis and are considered young onset. People with PD experience movement (motor) problems including slowness, rigidity, and tremor. Balance and gait problems may occur as the disease progresses. Some people may also experience decreased facial expression, low voice volume, small handwriting, and difficulty with fine motor movements. A number of non-motor symptoms are associated with PD, including depression and other emotional changes; difficulty in swallowing, chewing, and speaking; urinary problems or constipation; skin problems; and sleep disruptions. It is important to understand that symptoms vary from person to person. The American Parkinson Disease Association (APDA) PD Handbook provides an expanded description of signs and symptoms. Dr. James Parkinson, an English physician, first described the disease as shaking palsy in It was not until the 1960s, however, that research revealed that in PD there is a reduction of a brain chemical (neurotransmitter) called dopamine. Motor symptoms of PD result from the loss of the pigmented dopamine neurons (brain cells) in the substantia nigra region of the brain. Dopamine is responsible for smooth, purposeful movement. Despite advances in research, the exact cause of dopamine neuron loss is still unknown. Decreases in dopamine, however, do not account for all symptoms experienced in PD. Research is ongoing to better understand more about the biology of Parkinson s and all of the changes that occur in the brain due to the disease.
7 APDA SERVICES Health and Wellness Support groups are a wonderful way to receive practical information and education about living with PD. Support groups, exercise, stress, and nutrition programs are offered. Education Up to date educational programs and information are provided through our website, a quarterly e-newsletter, a series of free publications and supplements, and regional programs. Nationwide Network of Chapters APDA s nationwide network of Chapters provides information and referral, education and support programs, health and wellness activities, and events to facilitate a better quality of life for the Parkinson's community. It is this grassroots structure that distinguishes APDA from other organizations serving people with Parkinson's disease. Information & Referral (I&R) Centers I&R Centers, are staffed by a medical director and coordinator. They offer physician and services referrals, establish and maintain support groups, and offer free support and education. RESEARCH Since its beginnings, APDA has supported innovative research and passionate, dedicated scientists, with the ultimate goal of Finding a Cure for Parkinson s disease. Cutting-edge research continues to make a substantial impact in the areas of genetics, drug discovery, animal models, and new therapies. APDA has funded most of the important Parkinson discoveries in the past 50 years, including the work of Dr. George Cotzias, who established the effectiveness of high oral doses of the medication levodopa in treating this debilitating disorder. Learn more at
8 This therapy remains the gold standard of Parkinson s treatment today. APDA supported the work of renowned scientist Dr. Roger Duvoisin and his team that led to identifying the role of heredity and environment in PD; and the work of Dr. Lawrence Golbe, whose team located the first causative mutation for Parkinson s disease: PARK1 in the alpha-synuclein gene. This work changed the direction of research by identifying an entirely new protein whose manufacture, function or breakdown could be the key to the disease. An important objective for APDA is providing funding for young investigators pursuing promising research initiatives with the potential to change lives. We support scientists like Dr. Talene Yacoubian, who studies the pathophysiology of Parkinson s disease to develop innovative new therapies, and Dr. Clemens Scherzer, who uses the latest genomic approaches to diagnose and treat Parkinson s disease. Specialized Centers Recognizing that the challenges of PD are different according to age and occupation, APDA has created national centers dedicated to varying needs: National Young Onset Center Addresses the unique challenges to younger people with PD and their families. Visit or contact (800) or young@apdaparkinson.org. National Resource Center for Rehabilitation at Boston University Provides phone access to a licensed physical therapist who can answer questions about exercise, educational materials, and available resources. Contact (888) or rehab@bu.edu. National Veteran s Center A centralized resource dedicated to supporting and improving the lives of Veterans with Parkinson s Disease. Call (888) , Ext or susan.gulas@va.gov for members of the U.S. armed forces and their families.
9 DID YOU KNOW? In the United States, every nine minutes someone is told they have Parkinson's disease. APDA S GRASSROOTS REACH We re in cities, towns, and communities across the United States. It s what makes APDA unique. APDA is the country s largest grassroots organization serving those touched by Parkinson s disease. Through our wide network of chapters, Information and Referral (I&R) Centers, Centers for Advanced Research, Specialized Centers (National Young Onset Center, National Resource Center for Rehabilitation at Boston University and National Veteran's Center) and countless support groups, we quickly reach people and connect them to resources that will provide the best outcomes as they navigate Parkinson s disease. APDA is in communities across the United States, supporting people with Parkinson s disease from the day of diagnosis throughout the Parkinson journey. APDA has been a funding partner in most major Parkinson s disease discoveries. We will continue to fund research initiatives that enable people with Parkinson s disease to lead lives that are as active as possible. Generous support for this brochure was provided by
10 ITEMS AVAILABLE FOR REQUEST Parkinson s Disease Handbook Be Active: An Exercise Program for People with Parkinson s Disease Living Well With Parkinson's Disease 10 Things You Can Do Now Living Well With Parkinson's Disease 10 Things You Can Do Now Spanish Fatigue in Parkinson s Disease Constipation & Parkinson s Disease Depression & Parkinson s Disease Incontinence & Parkinson s Disease Cognitive Changes in Parkinson s Disease For a complete listing of educational materials and patient support resources, please visit download-publications.
11 Your contribution supports: Health and wellness initiatives that deliver programs to help people maintain independence and optimism Education, communication, and support programs that share care and treatment options and connect people with Parkinson s disease to one another Expedited and innovative research to develop promising clinical approaches and better outcomes Funding of the next generation of scientists dedicated to finding new treatments and a cure Here are just a few ways to donate today: Become a monthly supporter, and your recurring gift ensures stable funding throughout the year. Double your gift through a corporate matching gift program. Ask your company s human resources office to find out if your company has one. Give a donation as a memorial or tribute to honor a loved one or dear friend while at the same time giving hope and optimism to others. Leave your legacy by naming APDA in your will planned giving is one of the simplest and most effective ways to make a difference. To make your donation now, visit the APDA website at or call (800) American Parkinson Disease Association is exempt from federal income taxes under Section 501(c) (3) of the Internal Revenue Code.
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