Day 1: Monday, October 24, 2016

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1 Day 1: Monday, October 24, 2016 Registration fast 8:30am 9:00am 10:30am 10:45am Welcome and Opening: HIV in Ontario How close are we to the UN AIDS targets? What about new infections? What do we need to do to reach the endgame? Co Chairs: Anita Rachlis and Tony Di Pede Minister of Health or Frank McGee, AIDS Bureau Mark Gilbert, Ontario HIV Treatment Network Sean B. Rourke, University of Toronto, Ontario HIV Treatment Network Plenary: HIV Management in 2016: Progress and Challenges Do we have the ARTs we need? What s in the pipeline? How does chronic immune activation affect treatment? What about drug resistance? Co Chairs: TBD and Robert Reinhard Ian Frank, Penn Institute for Immunology Eric Arts, University of Western Ontario David Knox, Maple Leaf Medical Clinic Concurrent s: HIV Care Quandaries: Let s Talk Cases Managing viral load/issues for immunological non responders Prescribing PrEP Managing drug resistance TBD What s gender got to do with it? Treatment and prevention 12:00pm 1:00pm Networking Lunch Plenary: Managing Patients with Complex Social, Mental Health and Addiction Issues How do issues like depression, opioid dependence, trauma and intimate partner violence affect health outcomes for people living with HIV? How can care providers address these issues in culturally appropriate ways? Co Chairs: Tim Guimond and Daniel Pugh Evan Collins, University of Toronto Conall O Cleirigh, Massachusetts General Hospital Reed Siemieniuk, McMaster University Jen Edelman, Yale University

2 Day 1: Monday, October 24, :30pm Concurrent s OCFP Poverty Assessment: what it is and how to integrate it into clinical practice Complex mental health and addiction cases A depression intervention delivered by nurses Screening for and responding to intimate partner violence Strategies for caring for people who use substances during hospital admissions 3:45pm 4:00pm 5:00pm 5:30pm Plenary: What s in the Biomedical Prevention Pipeline? What is the current research on HIV prevention? What are some of the challenges clinicians face when discussing prevention with patients? Co Chairs: Rupert Kaul and TBD Angela Kashuba, University of North Carolina Ian McGowan, University of Pittsburgh Plenary: Understanding HIV through Art A full understanding of HIV involves many different ways of knowing. In this panel discussion, three leading Toronto artists explore the relationship between their practice, HIV and community activism. Andrew Zealley, Mixed media artist Syrus Ware, Visual artist, Art Gallery of Ontario, Cultural Leaders Lab Alison Duke, Filmmaker, Goldelox Productions Reception and Poster

3 Day 2: Tuesday, October 25, :30am 10:00am 10:15am Plenary: Are Co Morbidities Different with HIV? What role does chronic inflammation play? What about family history? Does early detection of risk markers change outcomes? Are treatment strategies different for either HIV or the co morbidity? What about chronic pain? Co Chairs: TBD and Darien Taylor Alan Winston, Imperial College London Markella Zanni, Harvard Medical School Jessica Merlin, University of Alabama at Birmingham Concurrent s: Managing Co morbidities and Complications of HIV Managing metabolic complications of HIV Medication errors, drug interactions and polypharmacy Clinical and ethical issues in managing HCV co infection Managing pain Managing STIs 11:30am 12:45pm 2:00pm 3:15pm 4:15pm Plenary: Aging with HIV Advances in treatment mean that people with HIV are living longer than ever before. This is good news, but it also means that clinicians face unprecedented challenges as patients age. What is the latest research on aging with HIV? How can we help people living with HIV to thrive at every stage in life? Co Chairs: Sharon Walmsley and Adrian Betts Julian Falutz, McGill University Richard Harding, King s College London, UK Alice Tseng, University Health Network Lunch Presentation: Ontario s New Clinical Guidelines Gord Arbess, Evan Collins, Linda Robinson, Robert Reinhard Strategies to improve engagement and retention Providing culturally competent care Concurrent s Advanced care planning and palliative care Shared care models Can exercise and physical therapy reduce the impacts of aging? Plenary: How Close are We to a Cure? We remain hopeful that a cure for HIV is in our future, but how far do we still have to go? What questions do we still need to answer to find a cure? What promising research is underway? Co Chairs: Mario Ostrowski and Tola Mbulaheni Eric Cohen, Universite de Montreal Douglas Nixon, George Washington University Brad Jones, George Washington University

4 Day 2: Tuesday, October 25, :30pm 5:30pm Plenary: How Can we Win the Endgame? Thinking Outside the Clinical Care Box Even if we could stop all new infections, thousands of Ontarians with HIV will continue to need clinical care for many years until there is a cure. What are the best ways to optimize care? How clinicians are thinking outside the box to improve care? Co Chairs: TBD Oliver Bacon, UCSF Medical Center Claire Kendall, University of Ottawa Curtis Cooper, The Ottawa Hospital Closing Discussion: Getting to the HIV Endgame

5 Day 3: Wednesday, October 26, 2016 Planned in cooperation with ISNV fast 8:00am 8:30am 9:45am 10:00am 11:15am Welcome and Opening Remarks Plenary: How Aging, Comorbidities and Substance Use Affect the Brain For people with HIV, how do aging, comorbidities and substance use affect their brains? What are the neuro mechanisms? Are there strategies to protect the brain? Co chairs: TBD Ron Rosenes Dennis Kolson, University of Pennsylvania Howard Fox, University of Nebraska Medical Centre Plenary: Head and HAND biomarkers, neuroimaging, and neuroinflammation An in depth discussion of advances in neuro diagnostics and HIV associated neurocognitive disorders. Co chairs: Avi Nath & Maggie Atkinson Tricia Burdo, Boston College Bruce Brew, St. Vincent s Hospital, Sydney, Australia Lucette Cysique, University of New South Wales, Australia Abstract Driven Concurrent s Topic TBD Topic TBD Topic TBD 12:15pm 1:45pm Lunch Concurrent Tracks 1:45pm Track 1: Neuro mechanisms and pathogenesis 1: The CNS Reservoirs Eric Cohen, Université de Montréal Jon Karn, Case Western Reserve University Track 2: Implications of Neurovirology Discoveries for Clinical Care 1: A HAND diagnosis Why is it important? What are the implications for care? Chair: Julian Falutz Reuben Robbins, Columbia University

6 Day 3: Wednesday, October 26, 2016 Planned in cooperation with ISNV 3:00pm 3:15pm 2: Neuroinflammation, neuromechanisms and pathogenesis Fatah Kashanchi, George Mason University 2: Strategies to Manage Neurocognitive Impairments An overview of biomedical, clinical, and other interventions to help people with HIV delay or manage neurological issues. Chair: TBD Ned Sackter, Johns Hopkins Univeristy David Moore, University of California David Vance, University of Alabama 5:00pm ISNV Adjourned HIV and the Brain in 90 Minutes Key Implications of New Research for Clinical Practice Highlights of key findings. The 10 things you need to know in practice. Talk to the researchers. A special session for clinicians who were not able to attend the full conference. Chair: TBD 7:00pm ISNV Special Event Junior Scientists/Women in Neurovirology 6:30 8:00 pm Reception and poster session

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