Current Topics in Pathology

Transcription

1 Current Topics in Pathology Continuation of Ergebnisse der Pathologie 71 Editors c. L. Berry E. Grundmann W. H. Kirsten Advisory Board H.-W. Altmann, K. Benirschke, A. Bohle, H. Cottier M. Eder, P. Gedigk, Chr. Hedinger, S. Iijima J. L. Van Lancker, K. Lennert, H. Meessen, B. Morson W Sandritter, G. Seifert, S. Sell, T. Takeuchi H. U. Zollinger

2 Bone and Joint Disease Contributors M.E. Adams, M.E.J. Billingham, LM. Calder P.A. Dieppe, M. Doherty, F. Eulderink E. Grundmann, o. Haferkamp, B. Heymer P. A. Revell, A. Roessner, J. A. Sachs, R. Spanel Editor C.L. Berry With 110 Figures Springer-Verlag Berlin Heidelberg New York 1982

3 c.l. Berry, Professor Dr., Department of Morbid Anatomy. The London Hospital Medical College, GB-London El lbb E. Grundmann, Professor Dr., Pathologisches Institut der Universitiit, DomagkstraBe 17, D-4400 MunsterjWestf. WH. Kirsten, Professor Dr., Department of Pathology, The University of Chicago, 950 East 59th Street, Chicago, IL 60637, USA ISBN-13 : e-isbn-13 : DOl: / Library of Congress Cataloging in Publication Data Bone and joint disease. (Current topics in pathology; 71) Bibliography: p. Includes index. Contents: Examination of synovial fluid/p.a. Revell - The synovial biopsy/f. Eulderink - Tissue reactions to joint prostheses and the products of wear and corrosion/p.a. Revell - [etc.] I. Bones - Diseases. 2. Joints-Diseases. I. Adams, M.E. II. Berry, Colin Leonard, III. Series. [DNLM: I. Bone diseases. 2. Joint diseases. WI CU821H v. 71/WE 225 B712] RBI.E6 vol s [RC930.4] [616.7'107] AACR2 ISBN-13: (U.S.) This work is subject to copyright. All rights are reserved, whether the whole or part of the material is concerned, specifically those of translation, reprinting, re-use of illustrations, broadcasting, reproduction by photocopying machine or similar means, and storage in data banks. Under 54 of the German Copyright Law where copies are made for other than private use, a fee is payable to "Verwertungsgesellschaft Wort", Munich. by Springer-Verlag Berlin Heidelberg 1982 Softcover reprint of the hardcover 1st edition 1982 The use of registered names, trademarks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. 2122/

4 List of Contributors Adams, Dr. ME. Acute Care Unit, Health Sciences Center Hospital, University of British Columbia, 2211 Wesbrook Mall, Vancouver, B.C., V6T lw5, Canada Billingham, Dr. ME.J. Bioscience I Department, Pharmaceuticals Division, Imperial Chemical Industries P.L.C., Mereside, Aldedey Park, GB-Macclesfield, Cheshire SKI0 4TG Calder, Dr.I.M. Dieppe, Dr. P.A. Doherty, Dr. M. Eulderink, Prof Dr. F. Grundmann, Prof Dr. E. Ha[erkamp, Prof Dr. O. Heymer, Prof Dr. B. Revell, Dr. P.A. Roessner, Dr.A. Department of Morbid Anatomy, Institute of Pathology, The London Hospital, Whitechapel, GB-London El IBB Department of Medicine, Bristol Royal Infirmary, University of Bristol, GB-Bristol BS2 8HW Department of Medicine, Bristol Royal Infirmary, University of Bristol, GB-Bristol BS2 8HW Pathologisch Laboratorium, Universitair Medisch Centrum, Wassenaarseweg 61, NL-2333 AL Leiden Pathologisches Institut der Universitiit MUnster, DomagkstraBe 17, D-4400 MUnster/Westf. Abteilung fur Pathologie, Universitiit Ulm, Oberer Eselsberg, D-7900 Ulm/Donau Abteilung fur Pathologie, Universitiit Ulm, Oberer Eselsberg, D-7900 Ulm/Donau Department of Morbid Anatomy, The London Hospital Medical College, Turner Street, GB-London El 2AD, Pathologisches Institut der Universitiit MUnster, Domagkstra& 17, D-4400 Mi.inster/Westf.

5 VI Sachs, Dr. I.A. Spanel, Dr. R. Department of Immunology, The London Hospital Medical College, Turner Street, GB-London El 2AD. Currently: Laboratory of Immunogenetics, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20205, USA Abteilung ftir Pathologie, Universitat Ulm, Oberer Eselsberg, D-7900 Ulm/Donau

6 Preface The enormous importance of the diseases of the locomotor system in all populations and the large component of general clinical practice which they represent have not, in the past, been matched by an appropriate pathological effort. Increasing expectation of an active and long life has resulted in a great increase in specialisation in Rheumatology and rehabilitation of those with crippling diseases. This volume presents many of the pathological advances that have followed this clinical interest, beginning with reviews of changes in biological materials obtained by invasive investigation of joints, continuing with an account of therapy Goint replacement) and also describing a "new" hazard - hyperbaric injury. Experimental models of joint disease are also described as are other entities such as crystal deposition disease. A detailed consideration of the electron microscopy of bone tumours is included since this data is not widely available in current texts. Finally, the role of the HLA system in rheumatic disease is included, indicating the value of close co-operation between clinician and pathologist in defining and linking the various rheumatic syndromes. London

7 Contents Examination of Synovial Fluid. With 9 Figures P.A. Revell..... The Synovial Biopsy. With 20 Figures F. Eulderink Tissue Reactions to Joint Prostheses and the Products of Wear and Corrosion. With 20 Figures P.A. Revell Bone and Joint Diseases in Workers Exposed to Hyperbaric Conditions. With 10 Figures I.M Calder Experimental Models of Arthritis. With 7 Figures B. Heymer, R. Spanel, O. Haferkamp Electron Microscopy in Bone Tumor Diagnosis. With 35 Figures A. Roessner, E. Grundmann The Role of Particles in the Pathogenesis of Joint Disease. With 4 Figures P.A. Dieppe, M Doherty HLA Systems and Rheumatic Diseases. With 1 Figure J.A. Sachs Experimental Models of Degenerative Joint Disease. With 4 Figures M.E. Adams, M Billingham Subject Index Indexed in ISR