1. Chang, C.C., Lin, P.C., Lin, C.H., Yeh, K.T., Hung, H.Y., Chang, J.G.*, Rapid identification of CYP2C8 polymorphisms by high resolution melting

Transcription

1 1. Chang, C.C., Lin, P.C., Lin, C.H., Yeh, K.T., Hung, H.Y., Chang, J.G.*, Rapid identification of CYP2C8 polymorphisms by high resolution melting analysis. Clinica Chimica Acta, 413(1-2), Chang, C.Y., Tsai, E.M., Wu, C.H., Wang, C.L., Liu, C.M., Long, C.Y.*, Pelvic floor abscess secondary to gossypiboma following a total Pro lift procedure. Taiwanese Journal of Obstetrics and Gynecology, 51(2), Chang, H.W.*, Chuang, L.Y., Tsai, M.T., Yang, C.H., The Importance of Integrating SNP and Cheminformatics Resources to Pharmacogenomics. Current Drug Metabolism, 13(7), Chen, B.H.*,0 Hung, M.H., Chen, J.Y.F., Chang, H.W., Yu, M.L., Wan, L., Tsai, F.J., Wang, T.P., Fu, T.F., Chiu, C.C.*, Anti-allergic activity of grapeseed extract (GSE) on RBL-2H3 mast cells. Food Chemistry, 132(2), Chen, C.C., Liu, Y.S., Cheng, C.C., Wang, C.L., Liao, M.H., Tseng, C.N.*, Chang, H.W.*, High-throughput sex identification by melting curve analysis in blue-breasted quail and chicken. Theriogenology, 77(9), Chen, F.M.*, Chang, H.W.*, Yang, S.F., Huang, Y.F., Nien, P.Y., Yeh, Y.T., Hou, M.F., The mitogen-activated protein kinase phosphatase-1 (MKP-1) gene is a potential methylation biomarker for malignancy of breast cancer. EXPERIMENTAL AND MOLECULAR MEDICINE, 44(5), Chen, H.S., Chiang, P.H., Wang, Y.C., Kao, M.C., Shieh, T.H., Tsai, C.F., Tsai, E.M.*, Benzyl butyl phthalate induces necrosis by AhR mediation of CYP1B1 expression in human granulosa cells. Reproductive Toxicology, 33(1), Chen, J.B., Yang, Y.H., Lee, W.C., Liou, C.W., Lin, T.K., Chung, Y.H., Chuang, L.Y., Yang, C.H.*, Chang, H.W.*, Sequence-Based Polymorphisms in the Mitochondrial D-Loop and Potential SNP Predictors for Chronic Dialysis. Plos One, 7(7), e Chen, P.H., Tu, H.P., Wang, S.J., Ko, A.M.S., Lee, C.P., Chiang, T.A., Tsai, Y.S., Lee, C.H., Shieh, T.Y., Ko, C.H., Chiang, S.L., Ko, Y.C.*, Monoamine oxidase A variants are associated with heavy betel quid use. Addiction Biology, 17(4), Chen, Y.C., Tu, H.P., Wu, C.S., Ko, Y.C., Yu, H.S., Lu, Y.W., Li, W.C., Chen, G.S., Lan, C.C.E.*, Association between non-atopic hand eczema and interleukin-13 gene polymorphism in Taiwanese nursing population. Experimental Dermatology,21(12), Cheng, Y.C., Wang, C.C., Chen, Y.L., Wu, S.M.*, Large volume sample stacking with EOF and sweeping in CE for determination of common preservatives in cosmetic products by chemometric experimental design. ELECTROPHORESIS, 33(9-10), Chien, J.W., Chu, Y.T., Yang, S.N., Kuo, C.H., Wang, W.L., Kuo, P.L., Jong, Y.J., Hung, C.H.*, Long-Acting Beta 2 Agonists Suppress IP-10 Expression in Human Bronchial Epithelial Cells. Journal Of Investigative Medicine, 60(7), Chiu, C.C., Chou, H.L., Wu, P.F., Chen, H.L., Wang, H.M.*, Chen, C.Y.*, Bio-Functional Constituents from the Stems of Liriodendron tulipifera. Molecules, 17(4), Chou, C.H., Chuang, L.Y., Tseng, W.L., Lu, C.Y.*, Characterization of protein adducts formed by toxic alkaloids by nano-scale liquid chromatography with mass spectrometry. Journal of Mass Spectrometry, 47(10), Chuang, L.Y., Chang, H.W.*, Lin, M.C., Yang, C.H., Chaotic particle swarm optimization for detecting SNP-SNP interactions for CXCL12-related genes in breast cancer prevention. European Journal of Cancer Prevention, 21(4),

2 16. Chuang, L.Y., Lin, Y.D., Chang, H.W., Yang, C.H., An Improved PSO Algorithm for Generating Protective SNP Barcodes in Breast Cancer. PLoS One, 7(5), e Hasegawa, N., Abei, M., Fukuda, K., Kawashima, R., Seo, E., Wakayama, M., Hamada, H., Yokoyama, K.K., Obata, Y., Hyodo, I., Efficacy and Safety of Gene-Chemo Therapy Using Oncolytic Adenovirus Expressing Uracil Phosphoribosyl Transferase (UPRT) Followed by 5-Fluorouracil Administration in Syngenic Pancreatic and Biliary Cancers in Immunocompetent Adenovirus-Permissive Syrian Hamsters. MOLECULAR THERAPY, 20(1), S83-S Hsieh, T.H., Tsai, C.F., Hsu, C.Y., Kuo, P.L., His, E., Suen, J.L., Hung, C.H., Lee, J.N., Chai, C.Y., Wang, S.C., Tsai, E.M.*, n-butyl Benzyl Phthalate Promotes Breast Cancer Progression by Inducing Expression of Lymphoid Enhancer Factor 1. PLoS One, 7(8), e Hsieh, T.H., Tsai, C.F., Hsu, C.Y., Kuo, P.L., Lee, J.N., Chai, C.Y., Hou, M.F., Chang, C.C., Long, C.Y., Ko, Y.C., Tsai, E.M.*, Phthalates Stimulate the Epithelial to Mesenchymal Transition Through an HDAC6-Dependent Mechanism in Human Breast Epithelial Stem Cells. Toxicological Sciences, 128(2), Hsieh, T.H., Tsai, C.F., Hsu, C.Y., Kuo, P.L., Lee, J.N., Chai, C.Y., Wang, S.C., Tsai, E.M.*, Phthalates induce proliferation and invasiveness of estrogen receptor-negative breast cancer through the AhR/HDAC6/c-Myc signaling pathway. The FASEB Journal, 26(2), Hsu, P.C., Juo, S.H., Su, H.M., Chen, S.C., Tsai, W.C., Lai, W.T., Sheu, S.H., Lin, T.H.*, Predictor of poor coronary collaterals in chronic kidney disease population with significant coronary artery disease. BMC Nephrol,13(98). 22. Hsu, P.C., Lin, T.H., Su, H.M., Juo, S.H., Lai, W.T., Sheu, S.H.*, Association between Endostatin G4349A Polymorphism and Coronary Collaterals in the Chinese Population. ACTA CARDIOLOGICA SINICA, 28(1), Hsu, W.L., Tsai, M.H., Lin, M.W., Chiu, Y.C., Lu, J.H., Chang, C.H., Yu, H.S., Yoshioka, T.*, Differential effects of arsenic on calcium signaling in primary keratinocytes and malignant (HSC-1) cells. Cell Calcium, 52(2), Huang, L.J., Dong, H.P., Chuang, I.C., Liu, M.S., Yang, R.C.*, Attenuation of Mitochondrial Unfolded Protein Response is Associated With Hepatic Dysfunction in Septic Rats. Shock, 38(6), Huang, S.Y., Chen, N.F., Chen, W.F., Hung, H.C., Lee, H.P., Lin, Y.Y., Wang, H.M., Sung, P.J., Sheu, J.H., Wen, Z.H.*, Sinularin from Indigenous Soft Coral Attenuates Nociceptive Responses and Spinal Neuroinflammation in Carrageenan-Induced Inflammatory Rat Model. Mar Drugs, 10(9), Jang, M.Y., Long, C.Y., Chuang, S.M., Huang, C.H., Lin, H.Y., Wu, W.J., Juan, Y.S.*, Sexual dysfunction in women with ketamine cystitis: a case-control study. BJU International, 110(3), Ko, Y,C.*, Research on human burden/toxicants PREFACE. The Kaohsiung Journal of Medical Sciences, 28(7), S1-S Kuo, C.H., Li, C.H., Yang, S.N., Huang, M.Y., Chen, H.L., Kuo, P.L., Hsu, Y.L., Huang, S.K., Jong, Y.J., Wei, W.J., Chen, Y.P., Hung, C.H.*, Effect of Prostaglandin I-2 Analogs on Cytokine Expression in Human Myeloid Dendritic Cells via Epigenetic Regulation. Molecular Medicine, 18(1), Kuo, P.L., Hsu, Y.L., Tsai, M.J., Lien, C.T., Huang, M.S., Ko, Y.C.*, Nonylphenol Induces Bronchial Epithelial Apoptosis via Fas-mediated Pathway and Stimulates Bronchial Epithelium to Secrete IL-6 and IL-8, causing Bronchial Smooth Muscle Proliferation and Migration. Basic & Clinical Pharmacology & Toxicology, 110(2), Lan, C.C.E., Ko, Y.C., Yu, H.S., Li, W.C., Wu, C.S., Lu, Y.W., Yang, Y.H.*, Chen, G.S.*, Psoriatic patients with diabetes are prone to develop digestive organ cancers: A population-based study in Taiwan. Journal of Dermatological Science, 68(2), 82-8.

3 31. Lan, C.C.E., Ko, Y.C., Yu, H.S., Wu, C.S., Li, W.C., Lu, Y.W., Chen, Y.C., Chin, Y.Y., Yang, Y.H.*, Chen, G.S.*, Methotrexate Reduces the Occurrence of Cerebrovascular Events among Taiwanese Psoriatic Patients: A Nationwide Population-based Study. ACTA DERMATO-VENEREOLOGICA, 92(4), Lan, C.C.E., Wu,S.B., Wu, C.S., Shen, Y.C., Chiang, T.Y., Wei, Y.H.*, Yu, H.S.*, Induction of primitive pigment cell differentiation by visible light (helium-neon laser): a photoacceptor-specific response not replicable by UVB irradiation. Journal of Molecular Medicine, 90(3), Lee, C.C., Lin, Y.H., Chang, W.H., Wu, Y.C., Chang, J.G., The small molecule calactin induces DNA damage and apoptosis in human leukemia cells. European Journal of Cancer Prevention, 21(5), Lee, C.H., Hong, C.H., Yu, C.L., Wang, L.F., Clausen, B.E., Liao, W.T., Huang, S.K., Chen, G.S., Yu, H.S.*, Arsenic mobilizes Langerhans cell migration and induces Th1 response in epicutaneous protein sensitization via CCL21: A plausible cause of decreased Langerhans cells in arsenic-induced intraepithelial carcinoma. Biochemical Pharmacology, 83(9), Lee, C.H., Hong, C.H., Yu, W.T., Chuang, H.Y., Huang, S.K., Chen, G.S., Yoshioka, T., Sakata, M., Liao, W.T., Ko, Y.C., Yu, H.S.*, Mechanistic correlations between two itch biomarkers, cytokine interleukin-31 and neuropeptide beta-endorphin, via STAT3/calcium axis in atopic dermatitis. British Journal of Dermatology, 167(4), Lee, C.H., Ko, A.M.S., Yen, C.F., Chu, K.S., Gao, Y.J., Warnakulasuriya, S., Sunarjo, Ibrahim, S.O., Zain, R.B., Patrick, W.K., Ko, Y.C.*, Betel-quid dependence and oral potentially malignant disorders in six Asian countries. BRITISH JOURNAL OF PSYCHIATRY, 201(5), Lee, C.H., Lee, K.W., Fang, F.M., Wu, D.C., Tsai, S.M., Chen, P.H., Shieh, T.Y., Chen, C.H., Wu, I.C., Huang, H.L., Chen, B.H., Chang, C.H., Chen, M.K., Chou, S.H., Tsai, Y.S., Chiang, S.L., Ko, Y.C.*, The neoplastic impact of tobacco-free betel-quid on the histological type and the anatomical site of aerodigestive tract cancers. International Journal of Cancer, 131(5), Lee, S.C., Wang, C.C., Yang, P.C., Wu, S.M.*, Enantioseparation of (+/-)-threo-methylphenidate in human plasma by cyclodextrin-modified sample stacking capillary electrophoresis. Journal of Chromatography A, 1232, Lee, T.T.Y., Tsai, C.F., Hsieh, T.H., Chen, J.J.J., Wang, Y.C., Kao, M.C., Wu, R.M., Singh, S., Tsai, E.M., Lee, J.N., Ectopic Pregnancy-Derived Human Trophoblastic Stem Cells Regenerate Dopaminergic Nigrostriatal Pathway to Treat Parkinsonian Rats. PLoS One, 7(12), e Li, J.H., Ko, Y.C.*, Plasticizer incident and its health effects in Taiwan. The Kaohsiung Journal of Medical Sciences, 28(7), S17-S Li, J.H., Yu, W.J., Lai, Y.H., Ko, Y.C., Major food safety episodes in Taiwan: Implications for the necessity of international collaboration on safety assessment and management. The Kaohsiung Journal of Medical Sciences, 28(7), S10-S Lin, C.L., Chen, R.F., Chen, J.Y.F., Chu, Y.C., Wang, H.M., Chou, H.L., Chang, W.C., Fong, Y., Chang, W.T., Wu, C.Y., Chiu, C.C.*, Protective Effect of Caffeic Acid on Paclitaxel Induced Anti-Proliferation and Apoptosis of Lung Cancer Cells Involves NF-kappa B Pathway. International Journal of Molecular Sciences, 13(5), Lin, E., Lin, W.H., Wang, S.Y., Chen, C.S., Liao, J.W., Chang, H.W., Chen, S.C., Lin, K.Y., Wang, L., Yang, H.L., Hseu, Y.C.*, Flavokawain B inhibits growth of human squamous carcinoma cells: Involvement of apoptosis and cell cycle dysregulation in vitro and in vivo. The Journal of Nutritional Biochemistry, 23(4), Lin, K.L., Juan, Y.S., Lo, T.S., Liu, C.M., Tsai, E.M., Long, C.Y.*, Three-dimensional ultrasonographic assessment of compression effect on urethra following

4 tension-free vaginal tape and transobturator tape procedures. Ultrasound in Obstetrics & Gynecology, 39(4), Lin, P.C., Liu, T.C., Chang, C.C., Chen, Y.H., Chang, J.G.*, High-resolution melting (HRM) analysis for the detection of single nucleotide polymorphisms in microrna target sites. Clinica Chimica Acta, 413(13-14), Lin, Y.J., Kirchner, D.K., Guntert, P.*, Influence of H-1 chemical shift assignments of the interface residues on structure determinations of homodimeric proteins. Journal of Magnetic Resonance, 222, Lin, Y.T.*, Chen, G.Y., A Scaffold-Independent Subcellular Event-Based Analysis: Characterization of Significant Structural Modifications. JOURNAL OF CHEMICAL INFORMATION AND MODELING, 52(2), Linnert, M., Haupt, K., Lin, Y.J., Kissing, S., Paschke, A.K., Fischer, G., Weiwad, M., Lucke, C.*, NMR assignments of the FKBP-type PPIase domain of the human aryl-hydrocarbon receptor-interacting protein (AIP). Biomolecular NMR Assignments, 6(2), Liu, X.P., Huang, Y.C., Hung, W.C., Chen, W.T., Yu, H.S., Chai, C.Y.*, Sodium arsenite-induced abnormalities in expressions of Caveolin-1, enos, IKK beta, and COX-2 in SV-40 immortalized human uroepithelial cells and in urothelial carcinomas. Toxicology in Vitro, 26(7), Lo. T.S., Long, C.Y., Lin, Y.H., Lin, H.H., Doppler ureteric jet in urogenital prolapsed. International Urogynecology Journal, 23(1), Long, C.Y., Hsu, C.S., Wu, C.H., Liu, C.M., Wang, C.L., Tsai, E.M., Three-year outcome of transvaginal mesh repair for the treatment of pelvic organ prolapsed. European Journal of Obstetrics & Gynecology and Reproductive Biology, 161(1), Long, C.Y., Juan, Y.S., Wu, M.P., Liu, C.M., Chiang, P.H., Tsai, E.M.*, Changes in Female Sexual Function following Anterior with and without Posterior Vaginal Mesh Surgery for the Treatment of Pelvic Organ Prolapse. The Journal of Sexual Medicine, 9(8), Long, C.Y., Lo, T.S., Wang, C.L., Wu, C.H., Liu, C.M., Su, J.H., Risk factors of surgical failure following transvaginal mesh repair for the treatment of pelvic organ prolapsed. European Journal of Obstetrics & Gynecology and Reproductive Biology, 161(2), Long, C.Y., Wang, C.L., Hsu, C.S.*, Anterior vaginal cyst mimicking a cystocele assessed by transperineal ultrasound. European Journal of Obstetrics & Gynecology and Reproductive, 165(1), Shu, C.W.*, Liu, P.F., Huang, C.M., High Throughput Screening for Drug Discovery of Autophagy Modulators. Combinatorial Chemistry & High Throughput Screening, 15(9), Singh, S., Li, S.S.L.*, Epigenetic Effects of Environmental Chemicals Bisphenol A and Phthalates. International Journal of Molecular Sciences, 13(8), Singh, S., Li. S.S.L., Bisphenol A and phthalates exhibit similar toxicogenomics and health effects. Gene, 494(1), Suen, J.L., Hung, C.H., Yu, H.S., Huang, S.K., Alkylphenols-potential modulators of the allergic response. The Kaohsiung Journal of Medical Sciences, 28(7), S43-S Tang, J.Y., Chang, C.C., Lin, P.C., Chang, J.G., Isocitrate dehydrogenase mutation hot spots in acute lymphoblastic leukemia and oral cancer. The Kaohsiung Journal of Medical Sciences, 28(3), Tsai, M.J., Kuo, P.L., Ko, Y.C., The association between phthalate exposure and asthma. The Kaohsiung Journal of Medical Sciences, 28(7), S28-S Tsai, W.C., Wu, M.T., Wang, G.J., Lee, K.T., Lee, C.H., Lu, Y.H., Yen, H.W., Chu, C.S., Chen, Y.T., Lin, T.H., Su, H.M., Hsu, P.C., Cheng, K.H., Duh, T.H., Ko, Y.C., Sheu,

5 S.H., Lai, W.T.*, Chewing areca nut increases the risk of coronary artery disease in Taiwanese men: a case-control study. BMC Public Health, Wang, C.C., Chao, K.H., Chen, Y.L., Chang, J.G., Wu, S.M.*, Capillary electrophoretic genotyping of epidermal growth factor receptor for pharmacogenomic assay of lung cancer therapy. Journal of Chromatography A, 1256, Wang, C.C., Chen, J.L., Chen, Y.L., Cheng, H.L., Wu, S.M.*, A novel stacking method of repetitive large volume sample injection and sweeping MEKC for determination of androgenic steroids in urine. Analytica Chimica Acta, 744, Wang, Y.C., Chen, H.S., Long, C.Y., Tsai, C.F., Hsieh, T.H., Hsu, C.Y., Tsai, E.M., Possible mechanism of phthalates-induced tumorigenesis. The Kaohsiung Journal of Medical Sciences, 28(7), S22-S Yang, J.I., Yeh, C.C., Lee, J.C., Yi, S.C., Huang, H.W., Tseng, C.N.*, Chang, H.W.*, Aqueous Extracts of the Edible Gracilaria tenuistipitata are Protective Against H2O2-Induced DNA Damage, Growth Inhibition, and Cell Cycle Arrest. Molecules, 17(6), Yang, M.H., Jong, S.B., Lu, C.Y., Lin, Y.F., Chiang, P.W., Tyan, Y.C*., Chung, T.W.*, Assessing the responses of cellular proteins induced by hyaluronic acid-modified surfaces utilizing a mass spectrometry-based profiling system: Over-expression of CD36, CD44, CDK9, and PP2A. Analyst, 137, Yang, M.H., Yang, Y.H., Lu, C.Y., Jong, S.B., Chen, L.J., Lin, Y.F., Wu, S.J., Chu, P.Y., Chung, T.W., Tyan, Y.C.*, Activity-dependent neuroprotector homeobox protein: A candidate protein identified in serum as diagnostic biomarker for Alzheimer's disease. Journal of Proteomics, 75(12), Yang, Y.H., Kao Yang, Y.H.*, Cheng, C.L., Ho, P.S., Ko, Y.C., The role of chemoprevention by selective cyclooxygenase-2 inhibitors in colorectal cancer patients - a population-based study. BMC Cancer, Yang, Y.L., Chang, W.P., Hsu, Y.W., Chen, W.C., Yu, H.R., Liang, C.D., Tsai, Y.T., Huang, Y.H., Yang, K.D., Kuo, H.C.*, Chang, W.C., Lack of Association between CLEC5A Gene Single-Nucleotide Polymorphisms and Kawasaki Disease in Taiwanese Children. Journal of biomedicine & biotechnology,2012, Yeh, C.C., Yang, J.I., Lee, J.C., Tseng, C.N., Chan, Y.C., Hseu, Y.C., Tang, J.Y., Chuang, L.Y., Huang, H.W., Chang, F.R.*, Chang, H.W.*, Anti-proliferative effect of methanolic extract of Gracilaria tenuistipitata on oral cancer cells involves apoptosis, DNA damage, and oxidative stress. BMC Complement Altern Med, Yen, C.Y., Chiu, C.C., Haung, R.W., Yeh, C.C., Huang, K.J., Chang, K.F., Hseu, Y.C., Chang, F.R., Chang, H.W.*, Wu, Y.C.*, Antiproliferative effects of goniothalamin on Ca9-22 oral cancer cells through apoptosis, DNA damage and ROS induction. Mutation Research/Genetic Toxicology and Environmental Mutagenesis, 747(2), Zhong, H.J., Yang, H., Chan, D.S.H., Leung, C.H., Wang, H.M., Ma, D.L.*, A Metal-Based Inhibitor of NEDD8-Activating Enzyme. PLoS One, 7(11), e49574.