POSTER SESSIONSmBASIC SCIENCE BASIC SCIENCE

Save this PDF as:
Size: px
Start display at page:

Download "POSTER SESSIONSmBASIC SCIENCE BASIC SCIENCE"

Transcription

1 POSTER SESSIONSmBASIC SCIENCE BASIC SCIENCE S U N D A Y MAY 16 AASLD Poster Session Authors are required to be present during the Poster Session from 12:00-2:00 pm. Those posters identified as DDW Posters of Distinction have received review scores that place them within the top I0% of all posters. We encourage you to make them a priority as you visit the poster session. AM-5:00 PM Hall F NASH - EXPERIMENTAL Inhibition of Liver Fibrosis by Glutathione in a Rat $905 Model of Nash Kaoru lwata, Tetsuro Sohda, Yasuhiro Takeyama, Yuko Uehara, Makoto Irie, Akira Anan, Yuji Kitamura, Norihisa Suzuki, Hiroshi Watanabe, Shotaro Sakisaka Effect of Losartan on Liver Fibrosis Development in a $906 Rat Model of Non-Alcoholic Steatohepatitis Patricio Ibanez, Margarita Pizarro, Nancy Solis, Gloria Aguayo, Ignacio Duarte, Luigi Accatino, Marco A. Arrese Increase in Long-Chain Polyunsaturated Fatty Acid n-6/ $907 n-3 Ratio in Relation to Hepatic Steatosis in Nonalcoholic Fatty Liver Disease: Jaime M. Poniachik Sr., Julia Araya, Ramon Rodrigo, Luis Videla, Jorge Contreras, Atilla Csendes, Patricio Burdiles, Juan Carlos Diaz, Jorge Rojas, Fernando Maluenda, Lilian Thielemann, Gladys Smok Inverse Relationship Between DNA Repair Enzyme $908 Expression and Oxidative DNA Damage in Fatty Liver Diseases Daquing Gao, Shiqi Yang, Lei Chen, Jiawe Huang, Chiming Wei, Anna Mac Diehl In vivo and in vitro Hepatocyte Expression of $909 Peroxisome Proliferator Activated Receptor-Alpha (PPARa) by PPARa Ligands Filiz Akbiyik, Kubilay Cinar, E. Demirpence, D. Armstrong, R. Haziroglu, Cihan Yurdaydin, Ozden Uzunalimoglu, Hakan Bozkaya TLR2 Deficiency Increases Liver Damage in an Animal $910 Model of Non-Alcoholic Steatohepatitis Arumugam Velayudham, Angela Dolganiuc, Gyongyi Szabo Exendin-4, a Glucagon-Like Protein-1 (GLP-1) Receptor $911 Agonist, Reduces Hepatic Steatosis and Lipid Peroxidation in ob/ob Mice Xiaokun Ding, Neeraj K Saxena, Nitika A. Gupta, Frank A. Anania Differentially Expressed Genes in Mouse Liver During $912 Development of Fatty Liver Montserat Villagrasa, Dietmar M. Klass, Karlheinz Holzmann, Guido Adler, Michael Fuchs Combination of the NO-Releasing Derivative of $913 Ursodeoxycholic Acid, NCX-1000, with o~-tocopherol Provides Improved Protection of Mouse Hepatocytes in an In-Vitro NASH-like Setting Amine Ouazzani-Chahdi, Aziz Elimadi, Antoine Brault, Patrick Colin, Pierre Haddad Expression of Plasminogen Activator Inhibitor-1 and $914 Tissue-Type Plasminogen Activator in Liver of Rats with Nonalcoholic Fatty Liver Disease Fan Jiangao $915 Expression of Mitochondrial Uncoupling Protein 2 and Relationship to the Content of Adenosine Triphosphate in Liver of Rats with Nonalcoholic Fatty Liver Disease Fan Jiangao AASLD Poster Session AM-5:00 PM Hall F MoriaI Convention Center STELLATE CELL BIOLOGY $916 Opposing Effects of Estradiol and Progesterone on Intracellular Pathways and Activation Processes in the Oxidative Stress-Induced Activation of Cultured Rat Hepatic Stellate Cells Ichiro Shimizu, Mina Itonaga, Xinliang Cheng, Tatuzo ltagaki, Katutaka Sannomiya, Hirohito Honda, Susumu Ito, Susumu Ito Alpha5betal Integrin Regulates Type I Collagen $917 Synthesis in Early but Not Late Stages of Hepatic Stellate Cell Activation Milan Dodig, Ben O. Ogunwale, Srinivasan Dasarathy, Bingcheng J. Wang, Arthur J. McCullough Sex And Age Differences in Activation of Hepatic $918 Stellate Cells in Culture Milan Dodig, Srinivasan Dasarthy, Arthur J. McCullough oq[31 and ol2131 Integrins Have Contrasting Roles in the $919 Regulation of Ets-1 and Metalloproteinase (MMP)I Expression in Human Hepatic Stellate Cells (HSC) Cultured in Collagen Gel Iya Y. Znoyko, Maria Trojanowska, Adrian Reuben Activated Hepatic Stellate Cells Express Keratinocyte $920 Growth Factor in Chronic Liver Disease Marcus Muehlbauer, Heike Steiling, Juergen Schoelmerich, Sabine Werner, Claus Hellerbrand Blockage of Transforming Growth Factor 13 Receptors $921 Prevent Progression of Pig Serum-Induced, Rat Liver Fibrosis Wei Jiang, Chang Qing Yang, Wen B. Liu, Ji Y. Wang Inhibitory Effects of a Soluble Transforming Growth $922 Factor 13 Type I1 Receptor on the Activation of Rat Hepatic Stellate Cells in Primary Culture Mina Itonaga, Ichiro Shimizu, Xinliang Cheng, Tatuzo Itagaki, Katutaka Sannomiya, Hirohito Honda, Hikaru Ueno, Susumu Ito AM-5:00 PM Hall F Sponsored by: AGA; Liver and Biliary LIPID AND ORGANIC ANION TRANSPORT, METABOLISM AND SECRETION $923 Abnormal Hepatic Bile Acid Transport Associated with Defective Bile Acid Conjugation: Treatment with Glycoand Taurocholic Acids Ashok K. Batta, Gerald Salen, Holmes Morton, Victoria Carlton, Laura Bull, Benjamin Shneider P-112 ~ Denotes DDW Poster of Distinction

2 r POSTER SESSIONSmBASIC SCIENCE $924 $925 $926 $927 Alternative Exretory Routes for Accumulating Bile Acids via Adaptive Renal ABC Transporter Expression in Common Bile Duct-ligated (CBDL) Mice Martin Wagner, Peter Fickert, Hanns-Ulrich Marschall, Gernot Zollner, Dagmar Silbert, Andrea Fuchsbichler, Judith Gumhold, John D. Schuetz, Frank J. Gonzalez, Kurt Zatloukal, Helmut Denk, Michael Trauner L-Fabp Deletion Reverses Hepatic Steatosis in Fasted PPAR~ 4- Mice Elizabeth P. Newberry, Susan M. Kennedy, Nicholas O. Davidson Hepatic and Renal ABC Transporter Expression in Mice Depends on Gender and Changes in Pregnancy Martin Wagner, Peter Fickert, Gernot Zollner, Dagmar Silbert, Judith Gumhold, Andrea Fuchsbichler, Kurt Zatloukal, Hanns-Ulrich Marschall, Helmut Denk, Michael Trauner Usefulness of the Phenylalanine Breath Test for the Examination of Hepatic Function in Patients with Chronic Liver Disease Compared to the Methionine Breath Test Yukimoto Ishii, Shigeru Suzuki, Tomohisa Kohno, Kimitoshi Katoh, Yasuyuki Arakawa, Tadatoshi Takayama, Satoshi Asai Expression of Phase II-Metabolizing Sulfotransferases in $928 Normal and Diseased Human Gallbladder Sylvia Aust, Peter Obrist, Walter Jaeger, Martin Klimpfinger, Gerhard Tucek, Theresia Thalhammer Phenylalanine and Methionine Breath Tests Can $929 Evaluate Liver Function in Biliary Obstruction Masaru Aoki, Yukimoto Ishii, Tadatoshi Takayama AM-5:00 PM Hall F Mortal Convention Center Sponsored by: Gastrointestinal Oncology MOLECULAR GENETICS Apobec-1 Deletion Reduces Tumor Vascularity in $930 APC"~e+Mice Through Decreased Vascular Endothelial Growth Factor (VEGF) mrna Stability Debnath Mukhopadhyay, Jeffrey O. Henderson, Hanlin Wang, Nicholas O. Davidson Tumor Suppressor Smad4 Mediates Down-regulation of $931 the Anti-adhesive Invasion-promoting Matricellular Protein SPARC Martin W. Volmer, Yvonne Radacz, Kai Stuhler, Susanne Klein-Scory, Wolff Schmiegel, Helmut E. Meyer, Irmgard Schwarte-Waldhoff Differential Proteome Analysis of Gastrointestinal $932 Carcinoma Cell Lines Following Reconstitution of the Tumor Suppressor DPC4 Kai Stuehler, Irmgard Schwarte-Waldhoff, Helmut Meyer, Wolff Schmiegel, Stephan A. Hahn Impact of Smad4 on Cell Migration and Matrix $933 Production of Colon Carcinoma Cells Yvonne Radacz, Anna Schoeneck, Susanne Klein-Scory, Marc Zapatka, Wolff Schmiegel, Irmgard Schwarte-Waldhoff The Transcriptional Repressor SNAIL Regulates E- $934 Cadherin in Colon Carcinogenesis and During Chemoprevention Hemant K. Roy, Thomas Smyrk, Patrick Iversen, Jeniffer Koetsier, Thomas Victor, Ramesh K. Walt Multiple Colonic Adenomas and MYH Mutations: $935 Phenotype and Cancer Burden Analysis Susana Mao de Ferro, Paulo Fidalgo, Cristina Albuquerque, Pedro Lage, Paula Rodrigues, Celia Bahazar, Sofia Fragoso, Ines Vitoriano, Carlos Nobre Leitao Functional Analysis of the BRAF Mutations in Human $936 Colorectal Tumors Tsuneo lkenoue, Yohko Hikiba, Fumihiko Kanai, Yasuo Tanaka, Jun Imamura, Takaaki Imamura, Miki Ohta, Hideaki Ijichi, Keisuke Tateishi, Takayuki Kawakami, Masayuki Matsumura, Takao Kawabe, Masao Omata BRAF and KRAS Mutations in Hyperplastic Polyps: $937 Histologic Subtype and Location in the Colorectum Shi Yang, Francis A. Farraye, Charline Mack, Michael J. O'Brien FHL2 As a Co-Factor of XAF1 in the Induction of $938 Apoptosis Yi Yang, Marrie C. M. Lin, Y. P. Ching, S. K Lain, Harry H. X. Xia, ShuiPing Tu, Bing Zou, Jide Wang, Guoqing Li, Hua He, Qing Gu, Jun Zhong Peng, H. F. Kung, Benjamin C. Y. Wong Cdxl Expression Inhibits [$-Catenin/TCF $939 Transcriptional Activity in Human Colon Cancer Cells Rong J. Guo, Toshihiko Ezaki, EunRan Sub, John P. Lynch CDX2 Regulates Expression of Ceruloplasmin-Related $940 Protein Hephaestin in Intestinal and Colonic Epithelium Takao Hinoi, Galina Gesina, Aytekin Akyol, Rork Ktud<. Samir Hanash, Eric R. Fearon cis Elements of the Human CDX2 Gene Regulate $941 Expression of Transgenes in Mouse Colonic Epithelial Cells Takao Hinoi, Aytekin Akyol, Eric R. Fearon Autoregulation of Cdx2 Promoter in Gastric Carcinoma $942 Cell Lines Raquel Almeida, Jose A. Ahneida, Patricia Mesquica. ]acinca Serpa, Isabelle Van Seuningen, Filipe Santos-Silva, Cello Reis, Leonor David Co-ordinated Regulation of the Tumour Suppressor $943 Gene p16 by B-catenin-lef-1 and the Ets Transcription Family Claire Murphy, Mohamed E1-Tanani, Frederick C. Campbell The Role of Genetic Silencing by pl6ink4a and pl4arf $944 Promoter Methylation in UICC Stage I-III Colon Carcinoma Chih-Jen Hsieh, Oliver Nehls, Mario Sarbia, Franz Borchard, Hans-Helmut Gruenagel, Rainer Porschen, Michael Gregor, Bodo Klump DNA Methylation and Histone Acetylation Regulate $945 Expression of p16 and p21 in Human Colon Cancer Cell Lines Jing Yuan Fang, Yingxuan Chen, Juan Lu Characterization of Expression of Methyhhioadenosin $946 Phosphorylase (MTAP) in Normal Human Colonic Epithelial Cells and Colon Carcinoma Frauke Bataille, Gerhard Rogler, Marcus Muehlbauer, Susanne Wallner, Claus Hellerbrand, Anja-Katrin Bosserhoff Identification of an Inactive Truncation of Intestinal $947 Alkaline Sphingomyelinase in Human Colon Cancer HT- 29 Cells Jun Wu, Yajun Cheng, Ake Nilsson, Rui-Dong Duan Study on the Association Between COX-2,VEGF and $948 MVD Expression in Colorectal Adenocarcinoma Chunhua Qiu Vt Denotes DDW Poster of Distinction P-113

3 POSTER SESSIONS--BASIC SCIENCE I S U N D A Y MAY 16 Siah-lL, a Novel Siah-Family Protein, Regulates ~- $949 Catenin Activity in a p53-dependent Manner Akio lwai, Hiroyuki Marusawa, Shu-Ichi Matsuzawa, Toru Fukushima, Makoto Hijikata, John C. Reed, Tsutomu Chiba, Kunitada Shimotohno Increased Expression of Bcl2 Causes Transformation of $950 Normal Enterocytes (IEC18) by Increasing Proliferation and Inhibition of Apoptosis Diana Kazanov, Liora Madar-Shapiro, Eliezer Liberman, Ludmila Strict, Nadir Arber Role of LKB-1 (STK-11) in the Development of $951 Gastrointestinal Non-Hamartomatous Polyp SunYoung Won, Se Jin Jang, Joong Dal Lee Bone Marrow Contributes to Tumour Stroma $952 Natalie C. Direkze, Kairbaan Hodivala-Dilke, Rosemary Jeffery, Toby Hunt, Scan L. Preston, Malcolm R. Alison, Nicholas A. Wright Increased Mobilization of Bone Marrow Derived $953 Endothelial Progenitor Cells in the Peripheral Blood with Colon Cancer Progression Bayasi Guleng, Keisuke Tateishi, Miki Ohta, Hideaki Ijichi, Amarsanaa Jazag, Takaaki Imamura, Jun Imamura, Yasuo Tanaka, Tsuneo Ikenoue, Takayuki Kawakami, Fumihiko Kanai, Takao Kawabe, Masao Omata Patterns of ~-catenin Staining and Downstream Targets $954 of ~-Catenin/Tcf/Lef Transcription Reveal Modes of Growth of Colorectal Adenomas: Evidence Against 'Top- Down' as a Major Component of Clonal Expansion Scan L. Preston, Dahmane Oukrif, Evangelos Kyriakides, George Elia, Ian C. Talbot, Ian P. Tomlinson, Natalie C. Direkze, Lara Lipton, Marco Novelli, Nicholas A. Wright Altered Function of KLF5 in Syngeneic Models of $955 Intestinal Tumor Progression Nicholas W. Bateman, Jennifer D. Black, Adrian R. Black Generation and Analysis of a Mouse Model of Klf5 $956 Overexpression in the Esophagus Jonathan P. Katz, Hiroshi Nakagawa, Bree G. Goldstein, Hann-Hsiang Chao, Lori S. Actman PKC-[3n Modulates Caco-2 Cell Growth in Soft Agar and $957 Apoptosis by a Kinase-independent Mechanism Beth Scaglione-Sewell, Reba Mustafi, Deborah Stoiber, Keith Lenchner, Matt Lyons, Marc Bissonnette AM-5:00 PM Hall F MoriaI Convention Center Sponsored by: Growth, Development and Aging MUCOSAL GROWTH FACTORS AND RECEPTORS Ghrelin in Barrett's Esophagus: Expression and Effects $958 on Cell Growth Peter C. Konturek, Agnieszka Nikiforuk, Vitally Kukharskyy, Martin Raithel, Eckhart G. Hahn, Steffen Muehldorfer Ghrelin" A Novel Humoral Mediator of Intestinal $959 Adaptation Talat Waseem, Mark S. Duxbury, Hiromichi Ito, Jan Rounds, Jose E. Gonzalez, David Lautz, Edward E. Whang, Stanley W. Ashley, Malcolm Robinson EGF Receptor Transactivation by Histamine and Gastrin $960 in Cultured Human Gastric Epithelial Cells Hanumantha R. Ancha, Kenneth M. Kaufman Jr., Angela Ward, Richard F. Harry EGF-Stimulated Intestinal Epithelial Cell Migration $961 Requires Src-Dependent Activation of p38 MAP Kinase Mark R. Frey, Anastasia Golovin, D. Brent Polk EGF Receptor (EGFR) Signaling via ERK 1/2 Is $962 Modulated by Extracellular Cysteine/Cystine Redox in Caco-2 Cells Yvonne Nkabyo, Young-Mi Go, Dean Jones, Thomas Ziegler Epidermal Growth Factor Receptor (EGFR) $963 Transactivation ls Required for Angiotensin li- Stimulated Mitogenesis in Intestinal Epithelial Cells Terence Chiu, Chintda Santiskulvong, Enrique Rozengurt Growth Regulation by TGF-[~ Is Abrogated by Multiple $964 Mechanisms in Gastrointestinal Tumors in elf/smad4 Mutant Mice Wilma Jogunoori, Varalakshmi Katuri, Yi Tang, Bibhuti Mishra, Lopa Mishra Inhibitor of Differentiation (Id)-2 Is a Downstream $965 Target Gene of Transforming Growth Factor (TGF)-~ in the Regulation of Apoptosis Yanna Cao, Yah Liu, Lu Chen, E. Aubrey Thompson, Courtney M. Townsend Jr., Tien C. Ko Possible Roles of Hepatocyte Growth Factor Activator $966 Inhibitor Type 2 (HAI-2) Related Small Peptide (H2RSP) on the Intestinal Epithelial Growth and Differentiation Shuichiro Uchiyama, Hiroshi Itoh, Seiji Naganuma, Hiroaki Kataoka Regeneration of Injured Intestinal Mucosa Is Impared in $967 Hepatocyte Growth Factor Activator-Deficient Mice Hiroshi Itoh, Seiji Naganuma, Shuichiro Uchiyama, Hiroaki Kataoka Altered Expression of Hepatocyte Growth Factor $968 Activator Inhibitor type2 (HAI-2) Related Small Peptide (H2RSP) in Injured Intestinal Mucosa Seiji Naganuma, Hiroshi Itoh, Shuichiro Uchiyama, Hiroaki Kataoka Insulin Receptor Substrate-1 (IRS-1) Inhibits Apoptosis $969 and Protects Stem Cells in Mouse Small Intestinal Crypts Heather Wilkins, Shira Fruchtman, C. Randall Fuller, Yah Ling, Pauline Lund Targeted Expression of PC4/TIS7 in Intestine and Liver $970 Alters Body Weight, Adiposity, Intestinal Length and Circulating IGF-1 in Transgenic Mice Yuan Wang, Hristo Iordanov, Yi Lu, Elzbieta A. Swietlicki, Marc S. Levin, Deborah C. Rubin Suppressors of Cytokine Signaling (SOCS) Limit $971 Fibrogenic Actions of Growth Hormone and Insulin-Like Growth Factor-I in Intestinal Myofibroblasts Shira Fruchtman, James G. Simmons, C. Randall Fuller, ChrisChristopher Greenhalgh, P. Kay Lund Role of Suppressor of Cytokine Signaling-2 (SOCS-2) in $972 IGF-I Action in Intestinal Growth Carmen Z. Michaylira, C. Randall Fuller, Christopher Greenhalgh, Joan K. Heath, Pauline K. Lund TNFa and IGF-I Have Additive Effects on Collagen $973 Accumulation and Proliferation of Intestinal Myofibroblasts and TNF~ Action Requires TNFR2 Arianne L. Theiss, James G. Simmons, C. Randall Fuller, Pauline K. Lurid Tumor Necrosis Factor (TNF) Regulates Survival of $974 Intestinal Epithelial Cells by a Receptor-Dependent Mechanism Fang Yah, Sutha K. John, Steven J. McElroy, D. Brent Polk P-1t4 ~ Denotes DDW Poster of Distinction

4 POSTER SESSIONS--BASIC SCIENCE S975 Increased Apoptosis in Stat6 Deficient Cell Lines May Be Due to Interactions Between Stat6 and NF-KB Eva Galka, Jennifer L. Thompson, Lisa S. Poritz, Leo Fitzpatrick, Wen Jie Zhang, Waiter A. Kohun STAT-1 Signaling Is a Critical Downstream Mediator of $976 Enterocyte Proliferation and Intestinal Adaptation Marcus D. Jarboe, Wolfgang Stehr, Nicole P. Bernal, Sherri A. Profitt, Yufang Zhang, Christopher R. Erwin, Brad W. Warner Oxidative Stress-Induced Activation of Protein Kinase D 5977 in Intestinal Epithelial Cells Jun Song, Junghee Kang, Jing Li, Jingbo Qiao, B. Mark Evers, Dai H. Chung Modulation of ~-catenin Signaling by Casein Kinase I~ $978 (CKIc) in Native Epithelia Joseph H. Sellin, Famourou Kourouma, Andrew P. Morris, Shahid Umar Akt Activation Blocks Apoptosis in Intestinal Epithelial $979 Cells by Inhibiting Caspase-3 After Polyamine Depletion Huifang M. Zhang, Jaladanki N. Rao, Xin Guo, Lan Liu, Tongtong Zou, Douglas J. Turner, Jian-Ying Wang Spatial Correlation Between Acetylcholine-induced $980 Calcium Signals and Acetylcholine-induced Cell Proliferation Along the Isolated Human Colonic Crypt Axis Alyson Parris, Amy Reynolds, Sarah Addison, Susanne Lindqvist, James Hernon, Theo Spahos, Richard Tighe, Michael Lewis, Jean Mackay, Denise Westgarth, Ian Fellows, Duncan Bell, Sandeep Kapur, Alyson Prior, Mark Williams Dual Role of the MEK/ERK Signaling in Senescence and $981 Transformation of Intestinal Epithelial Crypt Cells Marie-Josee Boucher, Nathalie Rivard Tumor Suppressor Gene p53 Regulates PGE~. Receptors $982 EP2 and EP4 Expression in Response to Genotoxic Injury Mark Smrmoski, Robert George, Shrikant Anant, Brian Dieckgraefe, Courmey W. Houchen Interaction with Nucleophosmin Regulates p53 Activity $983 in Normal Intestinal Epithelial Cells Following Polyamine Depletion Tongtong Zou, Jaladanki N. Rao, Xin Guo, Lan Liu, Huifang M. Zhang, Douglas T. Turner, Barbara L. Bass, Jian-Ying Wang Proteasome-regulated Stability of CDX2 Is Dependent $984 on CDK2 Activity Jim Boulanger, Claude Asselin, Nathalie Rivard The Chemokine SDF-1/CXCL12 Stimulates Intestinal $985 Epithelial Cell Migration and Barrier Integrity Jennifer M. Smith, Priscilla A. Johanesen, Michael B. Dwinell Discovery of Novel Activators of Serum Response $986 Element (SRE) in Epithelial Cells Aimee L Landry, Brian Seed, Ramnik Xavier Indian Hedgehog Is an Antagonist of Wnt Signaling and $987 Regulates Differentiation in Colonic Epithelial Cells Sylvia Bleuming, James Hardwick, Berber Schepman, G. Johan Offerhaus, Josbert Keller, Corinne Nielsen, William Garfield, Sander Van Deventer, Drucilla Roberts, Maikel Peppelenbosch, Gijs van den Brink Bone Morphogenetic Protein Pathway in Mature $989 Epithelial Cells of the Stomach Sylvia Bleuming, Maria Jesus Garcia Leon, Sander Van Deventer, Maikel Peppelenbosch, Gijs van den Brink Development and Resolution of Experimental Colitis in $990 Dipeptidyl Peptidase IV Knockout Mice Mark Geier, Catherine Abbott, Danik Tenikoff, Geoffrey McCaughan, Gordon Howarth NFKB and PPAR~/Are Involved in the Proliferative $991 Effect of Leptin on Colonic Mucosa Mohammad Abolhassani, Thomas Aparicio, H. Hashktorab, Carole Elbim, Andre Bado, lradj Sobhani Relative Stimulation of Superior Mesenteric Arterial $992 (SMA) Blood Flow by Enteral Nutrition and Glucagon- Like Peptide 2 (GLP-2)in Piglets John Stephens, Barbara Stoll, Xinfu Guan, Michael Helmrath, Doug Burrin Effects of Glucagon-like Peptide-2 (GLP-2) on Intestinal $993 Adaptation and Cytokine Expression in Parenterally Fed Rats with Short Bowel Syndrome Gary R. Martin, Osama Bawazir, Laurie E. Wallace, David L. Sigalet Chronic Psychological Stress Alters Epithelial Cell $994 Kinetics in Rat Ileum Gaelle Boudry, Jennifer Jury, Ping-Chang Yang, Johan D. Soderholm, Derek M. McKay. Philip M Sherman. Man" H. Perdue Gene Expression Profiles of Post-Resection Adapting $995 Crypt Enterocytes Isolated by Laser Capture Microdissection (LCM) Christopher R. Erwin, Marcus Jarboe. Nicole Boreal. Wolfgang Stehr, Mario k,led\edo~ ic. Maureet~ Sm fur, Brad Warner The immature Intestine Is Highly Responsive to Enlcral $996 Food Before Birth Per T. Sangild, Charlotte R B.lorm'ad, Ahigail I I=o\~dcn AM-5:00 PM H.iI f Sponsored by: Hormones, Transmitters, Growth Factors and Their Receptors ANIMAL MODELS: RECEPTOR OR HORMONE/KNOCKOUT TRANSGENICS Increased Mesenteric Afferent Sensitivity in SST2 $997 Receptor Deficient Mice Weifang Rong, Wendy J. Winchester, Gareth A. Hicks, David Grundy Evidence for a Role of IL-6 in Acute-TNBS-Induced $998 Colitis in Mice Jerome Gay, Michael O'Brien, Eft G. Kokkotou, Katia Karalis, Charalabos Pothoulakis Increased Visceral Pain Thresholds in CRF~ Receptor $999 Deficient Mice Anthony C. Johnson, Alan C. Foster, Beverley Greenwood- Van Meerveld Identification of Intestinal Genes Mediating the $988 Proadaptive Effects of Retinoic Acid (RA) Lihua Wang, Elzbieta A. Swietlicki, Yi Lu, Deborah C. Rubin, Marc S. Levin Denotes DDW Poster of Distinction P-115

5 POSTER SESSIONSmBASIC SCIENCE AM-5:00 PM Hall F Sponsored by: Hormones, Transmitters, Growth Factors and Their Receptors HORMONES/RECEPTORS: PATHOPHYSIOLOGIC BASIS OF DISEASE S1000 S1001 S1002 $1003 $1004 $1005 $1006 S1007 Ghrelin Stimulates NF-kb-Mediated Interleukin-8 Gene Expression in Human Colonic Epithelial Cells Dezheng Zhao Sr., Huiyan Zeng, Pauline Anton-Gay, Andrew C. Keates, Ciaran P. Kelly, Christos S. Mantzoros, Charalabos Pothoulakis Ghrelin Dynamics in Rats with Cysteamine-Induced Duodenal Ulcer Hidekazu Suzuki, Seiichiro Fukuhara, Tatsuhiro Masaoka, Yuka Abiko, Hiroshi Hosoda, Sachiko Nomura, Kenji Kangawa, Masaki Kitajima, Hiromasa lshii Cholecystokinin (CCK) Down Regulates PGE2and PGI2 Release in Inflamed Guinea Pig Gallbladder Smooth Muscle Cell Cultures Stuart 1. Myers, Mary P. Colvin, Michael R. Ruggieri Sr., Alan S. Braverman, Lori L. Bartula, Henry P. Parkman Estrogens Modulate Colonic Mucosal Functions in Vivo Silvia C. Resta-Lenert, Kim E. Barrett The Incretin Hormones GIP and GLP-1 in Diabetic Rats: Effects on Motility and Insulin Secretion Therese Edholm, Kenan Cejvan, Suad Efendic, Peter T. Schmidt, Per M. Hellstrom M3 Muscarinic Acetylcholine Receptor Regulates Gastric Mueosal Hyperplasia Caused by Hypergastrinemia in Omeprazole-Treated Mice Ryota Mochizuki, Takeshi Aihara, Yusuke Nakamura, Eiji Nakamura, Susumu Okabe, Hiroyasu Hirose GeneChip and Tissue Microarray Identification of Low Levels of Estrogen Receptor-1 Expression in GI Carcinoids is Correlatable with Disease Aggression Mark Kidd, Robert Camp, Shrikant Mane, lrvin M. Modlin Serotonin Inhibits MCT1 Activity by Retrieval of the Transporter from the Apical Membranes in Caco-2 Cells Ravinder K. Gill, Seema Saksena, Waddah A. Alrefai, Sangeeta Tyagi, Krishnamurthy Ramaswamy, Pradeep K. Dudeja AM-5:00 PM Hall F Sponsored by: Hormones, Transmitters, Growth Factors and Their Receptors HORMONES/TRANSMITTERS/RECEPTORS IN WEIGHT CONTROL AND DEVELOPMENT Bacterial Lipopolysaccharide (LPS) Inhibits Plasma $1008 Ghrelin in Fasted Rats: Mechanisms and Role in the Inhibition of Gastric Emptying and Feeding Lixin Wang, Nicole R. Basa, Almaas Shaikh, Andrew Luckey, David Heber, Vincent S. Wu, Yvette F. Tache Ghrelin-Induced Feeding Stimulatory Signal via Vagal S1009 Affernt Nerves is Important in Rats with Streptozotocin- Induced Diabetes Tatsuhiro Masaoka, Hidekazu Suzuki, Seiichirou Fukuhara, Sachiko Nomura, Yuka Abiko, Kumiko Kurabayashi, Hiroshi Hosoda, Kenji Kangawa, Hiromasa Ishii $1010 S1011 Inhibition of Intestinal Synthesis and Secretion of Apolipoproteins by Glucagon-Like Peptide-1 Xiaofa Qin, David D'Alessio, Shuqin Zheng, Qing Yang, Patrick Tso Use of Griffonia Simplicifolia II (GSII) to Isolate Metaplastic Mucous Cells from the Stomach Weiqun Kang, Yana Zavros, Merchant Juanita AM-5:00 PM Hall F Sponsored by: Hormones, Transmitters, Growth Factors and Their Receptors HORMONES/TRANSMITTERS/RECEPTORS: ACID SECRETION AND GI SECRETION/ABSORPTION $1012 S1013 $1014 $1015 $1016 S1017 S1018 S1019 S1020 S1021 S1022 NECA-Induced Fluid Secretion in Human Colonic Mucosa Is Not Mediated by Adenosine A2A or A2~ Receptors James Root, Ken Clark, Richard Borman Luminal Leptin Decreases Intestinal Glucose Absorption via Sodium-Glucose Transporter-I, SGLT-1 Robert Ducroc, Khalil Akasbi, Marion Buyse, Sandra Guilmeau, Helene Devaud, Andre Bado Apelln Stimulates Acid Secretion and Histamine Release in Rat Stomach Koji Yakabi, Shoki Ro, Teruyuki Tanaka, Shino Ohno, Mitsuko Ochiai, Tsuneko Onouchi, Susumu Kurosawa, Takashi Nakamura, Kiyoshige Takayama The GABAB Agonist, SKF-97541, Stimulates Gastric Acid Secretion in Mice Through a Gastrin-Dependent Mechanism Laura Piqueras, Vicente Martinez The 5-HT4 Receptor Agonist, Tegaserod, Stimulates Electrolyte / Water Secretion in the Rat Colon Eckhard Weber, Mario Bernhard, Hans-Juergen Pfannkuche Myristoylated Alanine-Rich C Kinase Substrate (MARCKS) Mediates Phorbol Ester-Stimulated Neurotensin Release Via Upstream PKC and Rho/ROK Pathways Jing Li, Kathleen L. O'Connor, Mark R. Hellmich, George H. Greeley Jr., Courmey M. Townsend Jr., B. Mark Evers Serotoninergic and Nitrergic Mediators of Intestinal Secretion in Human Jejunum Brian N. King, Sheikh M. Haque, John M. Kellum The Interaction Between Gastrin and Ghrelin on Acid Secretion in Rat Stomach Shoki Ro, Teruyuki Tanaka, Mitsuko Ochiai, Tsuneko Onouchi, Susumu Kurosawa, Takashi Nakamura III, Koji Yakabi, Kiyoshige Tanaka Characterization of 5-HT Receptor Subtypes Stimulating Chloride Secretion in the Guinea Pig Colon Eckhard Weber, Stefan Marcaletti, Mario Bernhard, Hans- Juergen Pfannkuche Chloride Influx in Rat Gastric Parietal Cells is Na+/K+/ 2C1" Cotransporter (NKCC) Dependent Ortrud Kosiek, Esad Vucic, Florian Grahammer, John P. Geibel Mechanism of Antagonist-Induced Up-regulation of Human Histamine H2 Receptor-GFP Fusion Protein Expressed in HEK293 Cells Satoshi Osawa, Masayoshi Kajimura, Seiji Yamamoto, Chihiro Mochizuki, Hirohiko lwasaki, Susumu Terakawa P Denotes DDW Poster of Distinction

6 POSTER SESSIONS~BASIC SCIENCE $1023 Neurogenic Mucosal Secretion Mediated by the Purinergic P2Y1 Receptor in Guinea-Pig Small Intestine Xiucai Fang, Hong-Zhen Hu, Sumei Liu, Guo-Du Wang, Na Gao, Xi-Yu Wang, Yun Xia, Jackie D. Wood $1033 Adenosine Is a Negative Regulator of NF-kappaB and MAPK Signaling in Intestinal Epithelial Cells Humberto B. Jijon, Judith Altarejos, John Walker, Karen L. Madsen S1024 Cyclooxygenase Inhibition in a Model of Neural Serotonin-Induced Chloride Secretion in Rat Distal Colon Brian N. King, Sheikh M. Haque, Luke G. Wolfe, John M. Kellum AM-5:00 PM Hall F Sponsored by: Hormones, Transmitters, Growth Factors and Their Receptors TOLL-LIKE RECEPTORS, THEIR LIGANDS AND CYTOKINE RECEPTOR SIGNALING $1025 Toll-like Receptors 2 and 4 are Upregulated on Human Lamina Propria Dendritic Cells in Intestinal Inflammation Ailsa Hart, Hafid Omar A1-Hassi, Michael Kamm, Stella Knight, Andrew Stagg AM-5:00 PM Hall F Sponsored by: Immunology, Microbiology & Inflammatory Bowel Disorders EPITHELIAL CELL IMMUNE FUNCTIONS $1026 S $1028 S1029 $1030 $1031 S1032 ADAM-9 Interacts with Interleukin-15 (IL-15) in Colonic Epithelial Cells (CECs) Martin Hausmann, Silvia Kellermeier, Stefan Kiessling, Tanja Spoettl, Katja Scbreiter, Wemer Falk, Juergen Schoelmerich, Hans Herfarth, Gerhard Rogler FcRn-Mediated Transcytosis of IgG Across Mucosal Barriers is Regulated by Calmodufin Bonny L. Dickinson, Richard S. Blumberg, Wayne I. Lencer The Serine Protease Trypsin Desensitizes Intestinal Epithelial Cells to Lipopolysaccharide Through Proteolysis of MD-2 Elke Carlo, Guido Gerken, Daniel K. Podolsky MHC II Expression on Gastric Mucosal Cells: Inhibition of Receptor Clustering and Protection from Fas Ag Signaling Calin Stoicov, Xun Cai, Hanchen Li, Jean Marie Houghton Interferon~/(IFN-'y)Selectively Suppresses TNF-~tinduced COXol and COX-2 Expression in Intestinal Epithelial Cells by Inhibiting NF-KB Function Ken Nally, Darren O'Bnen, Joe O'Connell, Fergus Shanahan Epithelial TLR5 Is Constitutively Focalized to the Mouse Cecum And Exhibit a Distinctive Down- Regulation During Experimental Colitis Cesar F. Ortega-Cava, Shunji Ishihara, Yoshikazu Kinoshita Peroxisome Profiferator-Activated Receptor-Gamma (PPAR~/) a Pivotal Key for Pro-lnflammatory Effect of Leptin on Human Epithelial Colonic Cells Mohammad Albolhassani, Jean-Claude Marie, Hassan Ashktorab, Andre Bado, Iradj Sobhani $1034 Changes in Colonic Paracellular Permeability Are Associated with Airway Challenge in Ovalbumin Sensitized Mice Helene Eutamene, Nicolas Cenac, Valerie Tondereau, Vassilia Theodor.ou, Rafael Garcia-Villar, Jean Fioramonti, Lionel Bueno AM-5:00 PM Hall F Sponsored by: Immunology, Microbiology & Inflammatory Bowel Disorders IBD: IMMUNOLOGY AND PATHOGENESIS $1035 $1036 S1037 S1038 S1039 S1040 S1041 S1042 S1043 Escherichia Coli (EC) Isolates from Crohn's Disease (CD) Tissues Are More Often Clonal, Motile and Associated with Single FlageUar Types Than EC from Control or Ulcerative Colitis (UC) Ying Mao, Chengru Zhu, Katherine Davis, Edgar C. Boedeker Consequence of Functional Nod2- and Tlr4-Mutations on Gene Transcription in Crohn's Disease Henri Braat, Pieter Stokkers, Floor de Kort, lnge Pronk, Esther Vogels, Maikel Peppelenbosch, Sander van Deventer, Daan Hommes Failure of the Acute Inflammatory Response in Crohn's Disease: The Influence of CARD15 Daniel J. B. Marks, Marcus Harbord, Bissan A1-Lazikani, ~ Minal Joshi, Stuart Bloom, Anthony W. Segal Analyzing Calcium Signals of Identified Human T-... Lymphocytes in Intact Human Intestinal Tissue Using ~:~'-'--~'~ =~= Two-Photon Microscopy -- - "- Eberhard Tutsch, Desiree Griesemer, Alexander Schwar:, Markus Hoth, Andreas Stal]mach,:v,:,a >a~=;~: ea~2,~.; <, In Vivo CpG DNA/TLR9 Ligation Induces Regulator)... Properties in CD4+CD62L+-T-Cells Which Prevent Intestinal Inflammation in the SCID-Transfer Model of Colitis Florian Obermeier, Ulrike Strauch, Nadja Dunger, Nicole Grunwald, Hans Herfarth, Juergen Schoelmerich, Werner Falk Blockade of CXCL10 Chemokine Reduces Recruitment of Effector Thl Cells to Inductive Sites in Lymphoid Tissues During Colitis in IL-10-/- Mice* Goo Lee, Jeffrey B. Brown, Jae G. Hyun, Yueming Tang, Andrew D. Luster, Terrence A. Barrett Identification of a Specific Peptide from Human Tropomyosin Isoform 5 (htm5) that Binds with HLA- DR2 and Induces T Cell Response in Ulcerative Colitis (UC) Kiron M. Das, Jianying Liu, Xin Geng, Jim J. C. Lin Expression of the ~-Opioid Receptor (MOR) Is Enhanced in Inflammatory Bowel Diseases (IBD) and Regulated by the NFKB Pathway David Philippe, Anne Tsicopoulos, Karel Geboes, Han Vorng, Jean-Frederic Colombel, Pierre Desreumaux Abnormalities of CD4+CD25 + T Regulatory Cells and FOXP3 Gene Expression in Inflammatory Bowel Disease (IBD) Zhonghui Wen, Gaff West, Manijeh Phillips, Claudio Fiocchi Denotes DDW Poster of Distinction P-117

7 S U N D A Y MAY 16 S1044 $1045 $1046 $1047 $1048 $1049 $1050 $1051 $1052 $1053 $1054 S1055 I POSTER SESSIONS--BASIC Inducible and Neuronal Nitric Oxide Synthases Activities in Proximal Colonic Mucosa Predict Evolution S1056 of Inflammatory Extension in Ulcerative Colitis Luis Menchen, Arturo Colon, Luis Behran, Sofia Botella, Ignacio Lizasoain, Juan-Carlos Leza, Maria Angeles Moro, Pedro Menchen, Pedro Lorenzo Differential Upregulation of Antiproteinases Elafin and SLPI in Human Colonic Epithelium During S1057 Inflammation Michael Schmid, Klaus Fellermann, Jan Wehkamp, Peter Fritz, Ulrich Klotz, Juergen Harder, Jens Schroeder, Eduard F. Stange S1058 Subtractive Screening Reveals Increased Expression of Moesin in Colonic Lamina Propria Fibroblasts (CLPF) from Inflammatory Bowel Disease (IBD) Mucosa Markus Lang, Martin Hausmann, Katja Schreiter, Tanja Spoettl, Juergen Schoelmerich, Werner Falk, Gerhard Rogler S1059 A Fully Human Anti-TNF mab Adalimumab (D2E7) Induces Caspase-Dependent Apoptosis of Human Peripheral Blood Monocytes and T Cells Chong Shen, Philippe Maerten, Gert Van Assche, Karel $1060 Geboes, Paul Rutgeerts, Jan Ceuppens Colitis-Associated Adenocarcinoma Development is Increased in Interleukin-10-deficient (IL-10-/-) Mice in the Absence of Chronic Nitric Oxide Production Donna-Marie McCafferty, Crystal Velichka $1061 Bone Marrow Derived Cells Mediate the Reduced Susceptibility of Inducible Nitric Oxide Synthase Deficient (inos -/-) Mice to Dextran Sodium Sulfate (DSS)-lnduced Colonic Injury S1062 Annie Li, Donna-Marie McCafferty, Chang-Wen Chen, Cathy MacNaughton, Keith Sharkey, Paul L. Beck Pathogenetic Mechanisms of Intestinal Inflammation in SCID Mice Following Adoptive Transfer of Donor Lymphocytes from SAMP1/YitFe Mice $1063 Giorgos Bamias, Charles T. Martin, Margarita N. Mishina, William G. Ross, Jesus Rivera-Nieves, Fabio Cominelli Lymphocytes from Mice with Spontaneous Ileitis Show Increased Reactivity Towards Fecal Antigens Giorgos Bamias, Charles T. Martin III, William G. Ross, Kazuhiko Sugawara, Jesus Rivera-Nieves, Fabio Cominelli S1064 Epithelial Structural Changes and Barrier Dysfunction Precede Active and Chronic Inflammation in the SAMP1/YitFc Model of Spontaneous Crohn's-Like Ileitis Kevin G.E. Scott, Brian K. Reuter, Leslie N. Hancock, Stephen M. Cohn, Jonathon B. Meddings, Fabio Cominelli, Peter B. Ernst, Theresa T. Pizarro S1065 Possible Role of T Regulatory Cell Dysfunction in the Pathogenesis of Chronic Ileitis Seen in the SAMP1/YitFc Murine Model of IBD Brian K. Reuter, Kevin G.E. Scott, Matthew I. Staples, Mohamed I. Dahman, Theresa T. Pizarro, Peter B. Ernst, Fabio Cominelli $1066 Increased Production of Eosinophil Specific Chemokine 'Eotaxin' in Inflammatory Bowel Disease Syed S. Hoque, Hazel Drummond, Subrata Ghosh Expression of Inducible Nitric Oxide Synthase (inos) mrna in Colonic Mucosa in Collagenous Colitis - Correlation to the Histological and Clinical Activity and the Effect of Budesonide Treatment $1067 Ole K. Bonderup, Jesper Bach-Hansen, Poul Madsen, Vibeke Vestergaard, Jan Fallingborg, Peter S. Teglbjaerg SCIENCE I Eosinophil Adhesion and Mediator Release is Augmented in Inflammatory Bowel Disease Luciane C. Coppi, Sara M. Thomazzi, Claudio S. R. Coy, Maria de Lourdes S. Ayrizono, Juvenal Ricardo N. Goes, Joao J. Fagundes, Ciro G. Montes, Edson Antunes, Jose G. P. Ferraz Neoangiogenesis: An Overlooked but Vital Component of Inflammatory Bowel Disease (IBD) Pathogenesis Silvio Danese, Carol de la Moire, Miquel Sans, Gaff West, Joseph Willis, Antonio Gasbarrini, Claudio Fiocchi Differential Patterns of Caspase Activation and Apoptosis in Crohn's Disease Versus Ulcerative Colitis Jan Heidemann, Henning R. Gockel, Andreas Lugering, Wolfram Domschke, Michael P. Manns, Klaus Schulze- Osthoff, Heike Bantel Role of Adaptors in Immune Modulation of Murine Colitis Ashish Chawta Interaction Between Dendritic Cells and T Cells in the Mesenteric Lymph Nodes of Inflammatory Bowel Disease Atsushi Sakuraba, Toshiro Sato, Nagamu Inoue, Hiromasa Ishii, Toshifumi Hibi Tissue Localisation of Human Colonic Dendritic Cells (DC) Is Altered in Inflammatory Bowel Disease (IBD) Hafid O. A1-Hassi, Angela Jones, Ailsa Hart, Ian Talbot, Michael Kamm, Stella Knight, Andrew J. Stagg Lymphocytic (LC) and Collagenous Colitis (CC) Are a Spectrum of the Same Disease - A Comparative Global Gene Expression Profile by Microarray Analysis Peter Tagkalidis, Gareth Price, Deon Venter, Peter Gibson, P. S. Bhathal Multidrug Resistance Gene (MDR-I) Expression in Intestinal Mucosa of Patients with Refractory Ulcerative Colitis (UC) Alicia M. Sambuelti, Sflvia M. Negreira, Anibal H. Gil, Sergio Huernos, Silvina Goncalves, Martin Toro, Zulema Kogan, Ana Cabanne, Sandra Camarero, Julio C. Bai, Alberto Lazarowski The Role of IL-15 and Ik-15 Receptor (IL-15r) in Immunoglobulin Synthesis of B Cells in the Intestinal Mucosa Tsuyoshi Nishiwaki, Kenji Ina, Kazuo Kusugami, Takafumi Ando, Osamu Watanabe, Ryuichi Furuta, Hidemi Goto Single Dose of OCH But Not A-Galactosylceramide Improves Mucosal ThlFrh2 Cytokine Balance and Prevents Experimental Colitis in Mice Yoshitaka Ueno, Shiuji Tanaka, Masaru Shimamoto, Yoshihiro Miyanaka, Sachiko Miyake, Masaru Taniguchi, Takashi Yamamura, Kazuaki Chayama NOD2 (CARD15) Mutations in Chrohn's Disease are Associated with Diminished Mucosal Paneth Cell- Defensin Expression: A Possible Explanation for Ileal Involvement Jan Wehkamp, Juergen Harder, Michael Weichenthal, Matthias Schwab, Elke Schaeffeler, Miriam Schlee, Klaus R. Herrlinger, Andreas Stallmach, Peter Fritz, Jens M. Schroeder, Klaus Fellermann, Eduard F. Stange Immunopathological Roles of Secondary Lymphoid- Tissue Chemokine (SLC) and EBI1-Ligand Chemokine (ELC) in Crohn's Disease Takayuki Matsumoto, Daichi Kawashima, Makoto Inagawa, Kenji Watanabe, Yoshio Jin-No, Shiro Nakamura, Nobuhide Oshitani, Tetsuo Arakawa, Kiyoshi Maeda, Kousei Hirakawa, Atsuo Kitano P-118 ~ Denotes DDW Poster of Distinction

8 POSTER SESSIONSmBASIC SCIENCE S1068, S1069 S1070 S1071 $1072 $1073 $1074 $1075 $1076 S1077 $1078 S1079 $1080 Role of Neutrophils for the Initiation and Perpetuation of Chemical Induced Colitis Anja A. Kuehl, Nina N. Pawlowski, Christoph Loddenkemper, Katja Grollich, Thomas F. Tedder, Douglas A. Steeber, Martin Zeitz, Joerg C. Hoffmann Downregulation of the Thl-Directing Cytokine-Like Molecule Osteopontin in Inflamed Mucosa in Crohns Disease Marc Haeder, Claudia Hayford, Martin Zeitz, Bianca M. Wittig A Critical Regulatory Role of the Leucin Zipper Transcription Factor c-maf in Thl Mediated Experimental Colitis Benno Weigmann, Markus F. Neurath Expression of Suppressors of Cytokine Signaling (SOCS) in Ulcerative Colitis Yoshihiro Miyanaka, Shinji Tanaka, Yoshitaka Ueno, Masaru Shimamoto, Masao Morihara, Masaki Kunihiro, Masaharu Sumii, Kazuaki Chayama Lymphocyte Activation via MICA-NKG2D in Crohn's Disease Matthieu Allez, Vannary Tieng, Marc Lemann, Jean-Marc Gomet, Dominique Charron, Antoine Toubert Visilizumab, a Humanized non-fcr Binding Anti-CD3 Monoclonal Antibody, Induces Th2 Cytokine Bias in Human Peripheral Blood Mononuclear Cells Tanny Tsao, Jacky Woo, Jianmin Li, James Sheridan, Thierry Sornasse, Corine Klingbeil, Vladimir Vexler Visilizumab, a Humanized non-fcr binding Anti-CD3 Monoclonal Antibody, Induces Selective Apoptosis of Glueocortieoid-lnsensitive Activated T cells Much Faster than Azathioprine Jianmin Li, Can M. Nhan, Jacky Woo, Tanny Tsao, James Sheridan, Thierry Sornasse, Corine Klingbeil, Vladimir Vexler Lamina Propria Regulatory CD4 + CD25 high T Cells Are Increased in IBD Lesions Jochen Maul, Pamela Mundt, Martin Zeitz, Rainer Duchmann VI Analysis of Saccharomyces Cerevisiae and Other Yeasts in Faeces and Intestinal Tissue Specimens of Patients with IBD Sieglinde Angelberger, Walter Reinisch, Gabriele. Mitterdorfer, Alexander Teml, Christoph Oesterreicher, Helmut K. Mayer, Harald Vogelsang, Alfred Gangl, Wolfgang Kneifel, Clemens Dejaco Deficient Expression of the Regulatory T Cell Marker FOXP3 in the Lamina Propria Lymphocytes of Patients with Inflammatory Bowel Disease Prashant Ponda, Diana Kim, Lloyd Mayer Absence of CD8 +VI~5.1 + Regulatory T (TRE) Cells in Patients with Inflammatory Bowel Disease Does Not Reflect a Deficiency of TRE Precursors Prashaut Ponda, Lloyd Mayer Activated Dendritic Cells Are Significantly Increased in Inflamed Intestinal Mucosa of Inflammatory Bowel Disease Patients Daniel C. Baumgart, Diana Metzke, Bertram Wiedenmann, Axel U. Dignass High Expression of MDR-1 Gene in Crypt Epithelial Cells in Pouchitis Alberto Lazarowski, Zulema Kogan, Aria Cabanne, Silvia Negreira, Anibal Gil, Sergio Huernos, Silvina Goncalves, Martin Toro, Sandra Camarero, Ivan Doldan, Julio C. Bai, Alicia M. Sambuelli $1081 S1082 $1083 S1084 Nitric Oxide Synthase Inhibition in Collagenous Colitis Claudia Reinders Localization of Eosinophils to Different Subspecies of Nerves in Inflammatory Bowel Disease Claire M. Smyth, Sara Woods, Mona Thornton, Tony O'Grady, Gerald Gleich, Elaine Kay, Frank Murray, Richard W. Costello Eosinophils Display an Activated Phenotype in Clinically Active Inflammatory Bowel Disease Claire M. Smyth, Sara Woods, Tony O'Grady, Gerald J. Gleich, Elaine Kay, Frank Murray, Richard W. Costello Novel Specific Antibodies Against Insertion Element 900 of Mycobactreium Paratuberculosis in Japanese Patients with Crohn's Disease Hiroshi Nakase, Kazuichi Okazaki, Tsutomu Chiba AM-5:00 PM Hall F Mofial Convention Center Sponsored by: Motility & Nerve-Gut Interaction GASTROINTESTINAL SENSORY MECHANISMS S S S S1088 S1089 S1090 S1091 S1092 $1093 Mesenteric Afferent Sensitivity to Vascular Perfusion May Arise Through Mechanical Distortion Alan M. Brunsden, Samuel Jacob, Karna Dev Bardhan, David Grundy Mechanical Stimulation of Human Enterochromaffin- BON Cells Release Adenosine to Act at A3 Receptors Io Modulate 5-HI Release Jacqueline E. Wunderlich, Jianging Xue, Minsoo Kim, Najma H. Javed, Fievos Christofi, Zach 5unites, Jun Ge Yu. Iveta Grants, Helen J. Cooke Immunodeficiency and Visceral Hyperalgesia: A Putative Mechanism for Abdominal Pain in AIDS Patients Monica Verma-Gandhu, Premysl Bercik. Patricia Blennerhassett, Waliul Khan, Lu Wang, Penglci Zhou. Gervais Tougas, Stephen Collins Differential Afferent Sensitivity to Mucosal Lipopolysaccharide (LPS) from Salmonella Typhimurium and Escherichia Coli in the Rat Jejunum Chuanyong Liu, Mario H. Mueller, Wen Jiang, David Grundy, Martin E. Kreis High Threshold Rat Colonic Afferents Directly Respond to Mast Cell Degranulation in Acute Inflammation Jonathan R. Coldwell, Gordon L. Howarth, L. Ashley Blackshaw Sex-Related Differences in Visceral Sensitivity in Adult Rats with Neonatal Colon Pain Jing Wang, Xin Peng, Elie D. A1-Chaer Plastic Changes in the Role of N-Methyl-D-Aspartate (NMDA) Receptors in the Behavioral Responses to Colorectal Distension (CRD) in Adult Rats Exposed to Neonatal Colon Irritation (CI) Jing Wang, Jiangang Xie, Elie D. A1-Chaer Experimental Colitis Alters the Functional Properties of NMDA Receptors Expressed by Colon-Specific DRG Neurons in Rats Jichang Li, James A. McRoberts, Helena Ennes, Emeran A. Mayer N-Methyl-D-Aspartate (NMDA) Receptors Modulate the Response of Inferior Splanchnic Afferent Fibers to Colorectal Distension James A. McRoberts, Yuhua Wang, Emeran A. Mayer Denotes DDW Poster of Distinction P-119

9 POSTER SESSIONS--BASIC SCIENCE S1094 $1095 G-Protein B 3 Subunit (GNB3) 825 CC Genotype and the Manifestation of Functional Gastrointestinal Disorders Gerald Hohmann, Elisabeth Grote, Ute Braun-Lang, Sebastian Haag, Angelika Pietsch, Nicholas J. Talley, Winfried Siffert Propionate Reduces Colonic Hypersensitivity in Rats Fabrice Artigue, Sophie Bourdu, Magali Millecamps, Gilles Bommelaer, Alain Eschalier, Denis Ardid, Michel Dapoigny SlI09 Sl110 Methane Gas Induces Prolonged Duration and High Amplitude Contractile Activity in the Guinea Pig Ileum Mark Pimentel, Hyo Rang Lee, Oren Zaidel, Brian van den Burg, Sandy Park, Jeffrey L. Conklin Role of Sensory C-fibers in the Hepatic Vascular Protective Mechanisms Against Acute Liver Injury in the Rat Jaroslaw Biernat, Wieslaw W. Pawlik, Ryszard Sendur, Jolanta J. Jaworek, Artur Dembinski, Zygmunt Warzecha S U N D A Y MAY 16 S1096 S1097 $1098 S1099 Sll00 Sll01 Sll02 Sl103 Sl104 Neuronal Activation in the Nucleus Tractus Solitarius (NTS)Following Intrajejunal and Systemic Lipopolysaccharide (LPS) in the Rat Georgios Gakis, Mario H. Mueller, Chuanyong Liu, Joerg Glatzle, Jutta Hahn, David Grundy, Martin E. Kreis Repeated Application of Capsaicin Sensitises Chemical Nociception in the Jejunum Johann Hammer, Barbara Schmidt, Peter Hoher, Heinz F. Hammer The Effects of Ghrelin on Mechanosensitive Jejunal Afferent Responses to Distension Charles D. R. Murray, Charlotte E. Booth, Wendy J. Winchester, Anion V. Emmanuel Ileal Allograft Sensory Function Following Adult Intestinal Transplantation Onki Cheung, Sunnder Devgun, Michael Pezzone, Carlo Di Lorenzo, Geoffrey Bond, Kareem Abu-Elmagd, Arnold Wald Sensitisation of High Threshold Mechanosensitive Jejunal Afferent Fibres Following Chronic Vagotomy David Bulmer, Reza Rahmati, Gareth Hicks, Wendy Winchester, David Grundy Co-Sensitivity of Jejunal Vagal Afferent Fibres to 5-Hh Receptor Activation and Capsaicin but Not CCK David Bulmer, Gareth Hicks, Wendy Winchester, David Grundy Colonic Extraluminal Mechanoreceptors and Inflammation in the Rat Colon Jonathan R. Coldwell, Gordon L. Howarth, L. Ashley Blackshaw Up-Regulation of NR1 Subunit of N-Methyl-D-Aspartate (Nmda) Receptors in Adult Rats with Neonatal Colon Irritation (CI) and Behavioral Implications Jiangang Xie, Rodger H. Song, Jing Wang, Elie D. Al-Chaer Deleterious Effect of Systemic Alcohol on Reflexive Pharyngeal Swallow and Pharyngo-UES Contractile Reflex Rajesh Santharam, Candy Hofmann, Tanya Rittmann, Caryn Easterling, Mark Kern, Kulwinder Dua, Reza Shaker AM-5:00 PM Hall F Sponsored by: Motility & Nerve-Gut Interaction; AGA INTERCELLULAR SIGNALING IN ENTERIC NEURAL PATHWAYS Participants will be able to: Attendees will learn about neurotransmitters controlling gastrointestinal motility; Attendees will learn about the role of interstitial cells of Cajal, enteric glia and smooth muscle in controlling gastrointestinal motility; Attendees will learn about the role of ion channels in the control of gastrointestinal motility; Attendees will learn about intracellular signaling pathways in neural and non-neural cells in the gastrointestinal tract. Characterization of Two Regions with Clustered $1111 Promoters of the Human Neuronal Nitric Oxide Synthase Gene Florian Nagl, Hans-Dieter Allescher, Roland M. Schmid, Dieter Saur Selective Contribution of Presynaptic R-type Calcium $1112 Channels to Slow Synaptic Excitation of Myenteric AHtype Neurons Matthew DeVries, Megan Vessalo, James J. Galligan Are Different Gap Junctions Involved in Neuromuscular $1113 Interaction in Mouse Proximal Colon? Andrej Sibaev, Hans-Dieter D. Allescher, Martin Storr [3 Subunit Composition of nachr-mediated Relaxation $1114 of Mouse Colon David A. Schneider, Lindsay M. Fry, Mariella De Biasi Interstitial Cells of Cajal (ICC) Are Essential for $1115 Distention-induced Colonic Peristalsis: ICC-deficient (Ws/Ws) Rat Colon Showed No Peristalsis but High Compliance Shigeru Yamato Sl105 Differential Effect of Cannabinoid (CB)I Agonist on Jejunal Mesenteric Afferent Responses to Cholecystokinin, Serotonin and Capsaicin in Fed and Fasted Rats Wen Jiang, Simon Lal, David G. Thompson, David Grundy Endocannabinoids Stimulate VIP Release from and NO $1116 Production in Enteric Nerve Endings - Evidence for Both, A CB2 and a Non-CB1, Non-CB2 Receptor Manfred Kurjak, Andreas Hamel, Dieter Saur, Hans-Dieter Allescher Sl106 $1107 Sl108 The Herbal Preparation STW 5 (Iberogast/TM) Desensitizes Intestinal Afferent Responses to Mechanical and Chemical Stimuli in the Rat Chuanyong Liu, Olaf Kelber, Mario H. Mueller, Joerg Glatzle, Paul Enck, David Grundy, Martin E. Kreis Critical Evaluation of the Colorectal Distension-Induced Visceromotor Response in Normal Rats Peter G. McLean, Colleen Taylor, Pam Gaskin, Gareth Hicks, Wendy Winchester Assessment of Visceral Sensitivity Using Radio Telemetry in a Rat Model of Maternal Separation Olaf Welting, Rene van den Wijngaard, Maaike I. Hour, Marjoleen Nijsen, Wouter de Jonge, Guy Boeckxstaens Different Neural Circuitries Behind Cholera Toxin and S 1117 Distension Induced Jejunal Secretion in vivo Shirin Kordasti, Maria Sapnara, Evan Thomas, Joel Bornstein, Henrik Sjovall Cholinergic Modulation of Motor Innervation in the S 1118 Canine Internal Anal Sphincter Amanda Ritchie, Yulia Bayguinov, Sean M Ward, Kathleen D. Keef Mucosal Neuronal Responses in Citrobacter Rodentium- $1119 Induced Colitis in Mice Lee Boyer, Dolar Sidpra, Alison M. J. Buchan, Bruce A. Vallance, Kevan Jacobson P-120 Denotes DDW Poster of Distinction

10 POSTER SESSIONS~CLINICAL SCIENCE Sl120 Acupuncture Has a Beneficial Effect on Postoperative Ileus in Conscious Rats Jose N. Balestrini, Hiroyuki Fukuda, Daisuke Tsuchida, Theodore N. Pappas, Toku Takahashi Sl128 NANC Neuronal Activity Evokes Slow Wave Like Membrane Depolarizations in Human Jejunum Circular Smooth Muscle Cells Lei Sha, Gianrico Farrugia, Joseph H. Szurszewski $1122 Sl123 $1124 Sl125.$1126 $1127 Pathways Mediating Stimulation of CGRP Release by BDNF: Identification of an Autocrine Pathway and a Novel Paracrine Pathway Involving Stimulation of 5-HT Release by BDNF John R. Grider, Barbara E. Piland Altered Intestinal Motility and Permeability in a Transgenic Mice Model of Glia Disruption Anne-Catherine Aube, Julie Cabarrocas, Michel Neunlist, Franck Doulay, Roland Liblau, Jean-Paul Galmiche Effects of the Gliotoxin Fluorocitrate on Enteric Glia and Intestinal Motor Function Ester Fernandez, Yasmin Nasser, Winnie Ho, Catherine M. Keenan, Keith A. Sharkey Rundown of Fast Excitatory Synaptic Potentials During Trains of Stimulation in the Myenteric Plexus Jim Ren, James J. Galligan Mast Cells Are Important for the Development of Chronic Visceral Pain: A Study with Mast Cell Reconstitution in W/Wv Mice Willemijntje A. Hoogerwerf VI, Kelli Gondesen, Gary Klimpel, Bryan Kosler, Shu-Yuan Xiao, John Winston, William Willis, Pankaj J. Pasricha Spontaneous Rhythmic Calcium Activity in Intact Gallbladder Smooth Muscle Onesmo B. Balemba, Thomas J. Heppner, Adrian Boney, Mark Nelson, Gary Mawe Collagen XIX is a Determinant of Esophageal Muscle Transdifferentiation and Physiology Niv Mor, Hideaki Sumiyoshi, Sui Y. Lee, Scott Henderson, Shizuko Tanaka, Hidekatsu Yoshioka, Francesco Ramirez, Satish Rattan Sl129 $1130 Sl131 Sl132 $1133 $1134 $1135 Sl136 Upregulation of Urinary Bladder PAR1 and PAR2 mrna in a Model of Pelvic Organ Cross-Sensitization Ruomei Liang, Matthew O. Fraser, Michael A. Pezzone Serotonin Reuptake in Human Colonic Epithelial Cells Matthew D. Coates, Peter L. Moses, Gary M. Mawe, Kevin F. Foley Colitis Enhances Synaptic Transmission in Guinea-Pig Submucosal Nerve Circuits Alan E. Lomax, Gary M. Mawe, Keith A. Sharkey Regulation of ILl3 and ILl3 Receptors in Small Intestine in Nippostrongylus brasiliensis (Nb) Infected Mice Motoko Morimoto, Aiping Zhao, Justin Elfrey, Josepf F. Urban Jr., Terez Shea-Donohue Lactobacillus paracasei Normalizes Post-Infective Dysmotility In Vivo and Induces a Sustained Attenuation of Inflammatory Mediators Elena F. Verdu, Premysl Bercik, Gabriela Bergonzelli, Florence Rochat, Xian-Xi Huang, Patricia Blennerhassett, Irene Corthesy-Theulaz, Stephen M. Collins Experimental Antibody-Mediated Gastrointestinal Dysmotility Steven Vernino, Leonid G Ermilov. [_ci Sha. \-and:~ Lennon, Joseph H. Szurszewski Gut-Derived Mediators in Mesenteric Lymph Inhibit Gastric and Colonic Motility During Sepsis in Rals Joerg Glatzle, Michael H. Tuerck, M:~ri,~ H Nll~'llcr. Id,>- Meile, Michae] Kasparek, Helen E Rayhould. Marlin Krci,. Tilman T. Zittd Effects of Hyperglycemia on Responses of Gastric Vagal Sensory Neurons to Serotonin Kirsteen Browning CLINICAL SCIENCE AASLD Poster Session Authors are required to be present during the Poster Session from 12:00-2:00 pro. Those posters identified as DDW Posters of Distinction have received review scores that place them within the top 10% of all posters. We encourage you to make them a priority as you visit the poster session. AM-5:00 PM Hall F ALCOHOLIC LIVER DISEASE A Double Blind Randomized Controlled Trial of $1137 Infliximab Associated with Prednisolone in Acute Alcoholic Hepatitis Sylvie Naveau, Sylvie Chollet-Martin, Sebastien Dharancy, Philippe Mathurin, Pauline Jouet, Marie Astrid Piquet, Thierry Davion, Frederic Oberti, Axel Balian, Didier Ribard, Pierre-Henri Bernard, Nicolas Carbonell, Patrick Hastier, Victor de Ledinghen, Pascal Perney, Isabelle Rosa, Philippe Broet, Dominiuque Emilie Sl138 Sl139 Sl140 Sl141 Erythropoietin Increases Platelet Reactivity and Platelet Counts in Patients with Alcoholic Liver Cirrhosis. A Randomized, Double Blind, Placebo Controlled Study Monika Homoncik, Monika Schmid, Petra Jilma-Stohlawetz, Arnulf Ferlitsch, Markus Peck-Radosavljevic, Bernd Jilma Optimization of MELD Scale in Predicting Long-Term Mortality Rate in Patients with Alcoholic Hepatitis Laith H. Jamil, Winston Dunn, Larry S. Brown, Michael Malinchoc, K. V. Narayanan Menon, W. Ray Kim, Russell H. Wiesner, Patrick S. Kamath, Vijay Shah Is the HFE Heterozygote State an Innocent Bystander in Alcoholic Liver Disease? Ferga C. Gleeson, Eleanor Ryan, Sharon Barrett, John Crowe Severe Alcoholic Hepatitis Versus Advanced Cirrhosis: Prevalence of Sepsis,Hepatorenal Syndrome,Hyperfibrinolysis and Predictors of Mortality Sumita Verma, Ketan Ajudia, Michel Mendler, Allan Redeker Denotes DDW Poster of Distinction P-121

11 POSTER SESSIONS--CLINICAL SCIENCE AASLD Poster Session AM-5:00 PM Hall F Sl151 Treatment of Chronic Hepatitis C in Canadian Prison Inmates Henry V. Chung, Victor Wong, Elizabeth Lira, Eric Yoshida, John Farley S U N D A Y MAY 16 HEPATITIS C TREATMENT I Sl142 $1143 $1144 $1145 Sl146 Sl147 Impact of AZT on Anemia and EPO Use During PEG/ RBV Therapy for HCV in HIV-infected Persons Russell Goodman, Lisa Moorehead, Daniel Alvarez, Douglas Dieterich, Mark Sulkowski Changes of IFNAR-2 Expression on peripheral Blood Leukocytes During IFN Therapy for Chronic Hepatitis C Koji Ishii, Yasukiyo Sumino, Mie Shinohara, Naoko Takamura, Katsuhiko Matsumaru, Motoko Fujita, Kanami. Sasao, Masao Shinohara, Hidenari Nagai, Manabu Watanabe, Kazumasa Miki, Wataru Yamamuro There Is a Trend to Improved SVR for African- Americans Receiving High Dose Induction IFN alfa 2b + Ribavirin Therapy for Chronic HCV: Final Results of a Prospective, Randomized, Controlled, Multicenter Trial in a VA Population Steve Flamm, Charles Mendenhall, David Johnson, Maher Azzouz, Lawrence Lumeng, Vivek Huilgol, Ena Bromley, Kimberly Sipich Improved Medical Adherence and QOL with Cognitive Behavioral Therapy in Pts Receiving PEG IFN alfa 2b (1.5 mcg/kg/wk) + Ribavirin ( mg/day) Persists Through 48 Wks of Therapy: Results of a Prospective, Randomized, Controlled, Muhicenter Trial Steve Flamm, Anne Eshelman, Michael Lyons, Arnold Levin, Stuart Gordon, Andrew Muir, Geronimo Sahagun, Jeffrey Medoff, Scott Strohecker, Ken Flora, Kenneth Kohagen, Wayne Weng, Tina Jackson Enhanced Efficacy of Interferon-alpha and Ribavirin Combination by Selective Depletion of Infected Granulocytes and Monocytes: Studies in Patients with High Plasma HCV Viraemia Koji Sawada, Shinichiro Kashiwamura, Haruki Okamura, Kunio Ohnishi, Ken Fukunaga, Abby Saniabadi, Toshikazu Hada Two-Weeks Induction Therapy with Pegylated Interferon Decreases Early Viral Load Without Improving Sustained Virological Response Rate in Patients with Chronic Hepatitis C - Prospective, Randomized, Open Label Phase III Clinical Trial Wolfgang Vogel, H. Brunner, W. Lin, Rudolf Stauber, Michael Gschwantler, Bernhard Stadler, H. Ulmer, Austrian Hepatitis Study Group $1152 $1153 $1154 Sl155 $1156 Sl157 Sl158 $1159 Psychiatric Side Effects of Pegylated Interferon Alfa-2b as Compared to Conventional Interferon Alfa-2b in Patients with Chronic Hepatitis C Arne Schaefer, Michael Scheurlen, Herbert Csef, Michael R. Kraus Preemptive Therapy with Combination Pegylated Interferon and Ribavirin in Liver Transplant Recipients with Hepatitis C Virus Guy W. Neff, Christopher B. O'Brien, Kamran Safdar, Phil Ruiz, Pablo Bejarano, Marzia Montalbano, Eugene R. Schiff Viscum Album L and Solanum Lycopersicum Inhibit Fibrosis in Chronic Hepatitis C (HCV): A Pilot Study Friedemann Schad, Burkhard Matthes, Silke Biesenthal- Matthes, Dirk Buchwald, Harald Matthes National Multicenter Study of Eligibility for Interferon and Ribavirin Therapy in Patients Coinfected with HIV and Hepatitis C Edmund J. Bini, Sue Currie, Hui Shen, Norbert Brau, Warren Schmidt, Teresa L. Wright, VA HCV-001 Research Group Interferon-~ Pharmacokinetics and Hepatitis C Viral Dyrmmics: Possible Evidence for Early Interferon Escape Gerond Lake-Bakaar, Victoria Freeman, Simon Frost Outcomes of a Hepatitis C Screening Program at a Large Urban VA Medical Center Holly Groom, Eric Dieperink, Mark Willenbring, Lori Tetrick, Janet Durfee, James Johnson, Stephen Ewing, Dave Nelson, Herbert Stockley, Rhonda yon Drashek, Judith Garrard, Samuel B. Ho The Outcome of Hepatitis C Therapy in African Americans and Hispanics With Persistently Normal Transaminases Eric J. Lawitz, Norma S. Cantu, Stephen A. Harrison, Shailesh Kadakia, Frank Adams, Mitchell Davis, Richard Sperling, Naoky Tsai, Andrei Gasic, Tarum Kothari, K. P. Ganeshappa, James Cox, Barry Sanders, Bruce Silverman, Elias Ghandour, Jeffrey Medoff, Nezam Afdahl, Mark Mailliard, Michael Curry, Alamo Study Group Hepatic Fibrosis Influences Early Virological Response Rates in Chronic Hepatitis C (CHC) Anouk T. Dev, Keyur Patel, Andrew J. Muir, Dylan Matzinger, John G. McHutchison $1148 $1149 Sl150 Treatment of Patients with Chronic HCV Infection and Normal Liver Enzymes with PEG IFN alfa 2b + Ribavirin Is Effective: Results from a Prospective, Randomized, Controlled, Multicenter Trial Steve Flamm, Jeffrey Goldman, Joel Cahan, Gregory Nelligan, David Chua, Bradley Shapiro, Mohammad Bawani, Rockford Yapp, Edward Jurkovic, Tina Jackson A Prospective Multicenter Study t O Enhance the Efficacy of Interferon-(IFN)alpha 2b + Ribavirin Combination Therapy in Patients with High Plasma HCV Viraemia by Selective Depletion of Infected Leukocytes Koji Sawada, Naohiko Masaki, Shigeki Hayashi, Mikio Zenia, Tomohisa Ishikawa, Hiroki Takahashi, Kunio Ohnishi, Ken Fukunaga, Naoki Hara, Tetsuo Yamamoto, Toshikazu Hada, Gotaro Toda Antioxidant Treatment Does Not Substantially Ameliorate the Fall in Hemoglobin in HCV Patients Treated with Pegylated Interferon Alfa-2b and Ribavirin Bruce R. Bacon, Bradley L. Freilich, Joan M. Siegner, Rosemary O'Neill, Janay Kissinger, Joyce A. Hoffmann, Robert S. Britton, Adrian M. Di Bisceglie, Clifford A. Brass $1160 $1161 $1162 High Relapse Rate of Former I.V. Drug Users with Hepatitis C Treated with Consensus-Interferon (Infergen) and Ribavirin Thomas Witthoeft, Andreas Bruening, Diether Ludwig Hepatic Steatosis in Patients with Chronic Hepatitis C Is Associated with HCV Genotype and BMI but Is Not Associated with Advanced Hepatic Fibrosis or Response to Therapy Asif Qadri, David Barnes, William Carey, Kevin Edwards, Nizar Zein The Effect of Amantadine on Sustained Virologic Response When Added to Pegylated Interferon Alfa 2b + Weight Based Ribavirin In Previous Nonresponders and Relapsers Eric J. Lawitz, Stephen A. Harrison, Norma S. Cantu, Shailesh C. Kadakia, K. P. Ganeshappa, Frank Adams, Mitchell Davis, Richard Sperling, Naoky Tsai, Andrei Gasic, Tarum Kothari, James Cox, Barry Sanders, Bruce Silverman, Elias Ghandour, Jeffrey Medoff, Vajravel Prasad, Nezam Afdahl, Mark Mailliard, Michael Curry, Alamo Study Group P-122 Denotes DDW Poster of Distinction

12 POSTER SESSIONSmCLINICAL SCIENCE ;! Sl165 1, $1167 $1168 $1169 Efficacy of Pegylated Interferon and Ribavirin in Patients with Active Psychiatric illness Gitanjali Vidyarthi, William P. Boyd, Irma Cruz-Gonzalez The Older Chronic Hepatitis C Patients are Difficult to be Treated with Ribavirin and Interferon Yoshiaki Iwasaki, Koichi Takaguchi, Keiji Kita, Haruhiko Kobashi, Yasuyuki Araki, Toshiya Osawa, Mitsuhiko Kawaguchi, Minoru Tomita, Noriaki Hashimoto, Hiroshi Ikeda, Junnosuke Shimamura, Kazuhisa Yabushita, Toshinari Shimoe, Masaharu Ando, Tomonori Senoh, Masaki Ohmoto, Yasuhiro Makino, Toshitsugu Kobatake, Koji Manabe, Kohsaku Sakaguchi, Yasushi Shiratori End of Treatment Response for PEG-IEN + Weight- Based Ribavirin Nonresponders Retreated with IFN alfacon-1 + Weight-Based Ribavirin Carroll B. Leevy, G. Ramaraju, Chris P. Chalmers, Lawrence M Blatt Use of Opioid Analgesics in Patients with Hepatitis C Aaron D. Blackwell, Eftihia Linardatos, Ashlee J. Whitehead, David W. Indest, Marian Fireman, Peter Hauser How Long Should We Retreat Non-Responders For? Final Results of the Frontier Trial Matthew Nichols, Marcelo Kugelmas No Differences in Treatment Response to HCV in Mexican Americans Ramsey C. Cheung, Sue Currie, Hui Shen, Ke-Qin Hu, Samuel Ho, Lennox Jeffers, Edmund Bini, Teresa L. Wright, VA-HCV-001 Research Group Factors That Improve the Efficacy of Epoetin Alfa for Maintenance of Ribavirin Weight-Based Dosing (RBV WBD) Aijaz Ahmed, Cynthia Leung, Prista Charuworn, Judy Grossi, Ramsey C. Cheung, Emmet B. Keeffe AASLD Poster Session AM-5:00 PM LIVER TRANSPLANTATION ' Sl170 $1171 $1172 $1173 $1174 Hall F Hepatic Histologic Changes During Interferon Therapy for Recurrent HCV Infection Post-OLT Mazen Alsatie, Oscar W. Cummings, Romil Saxena, Rong A. Qi, Lawrence Lumeng, Hwan Yoo, Naga Chalasani, Suthat Liangpusakul, A. J. Tector, Paul Y. Kwo Treatment of Recurrent Hepatitis C Infection After Liver Transplantation: Randomized Controlled Trial of Peg Interferon Alpha 2b and Ribavirin Vs. Peg Interferon Alpha 2b,Ribavirin and Amantadine Satheesh Nair, Jeanie Lipscomb, Heather Malloy, George Loss, Ari Cohen, James Eason Severity of Recurrent Hepatitis C Infection in Patients Receiving Hepatitis B Core Antibody Positive Livers: A Case Control Study Satheesh Nair, George Loss, Jamie Blazek, Ari Cohen, James Eason Impact of Pegylated Interferon Alfa-2b and Ribavirin on Depression in Liver Transplant Recipients with Recurrent Hepatitis C Mitchell Challis, Joyce Rogge, Lynne Weaver, Sandeep Mukherjee Steroid-free Immunosuppression for Liver Transplantation Recipients with Hepatitis C - A Prospective Randomized Study Tomoaki Kato, Hideo Yoshida, Olivia Hung, Marzia Montalbano, Guy Neff, Kamron Sadfar, Eugene Schiff, Andreas Tzakis $1175 S1176 $1177 $ Sl179 Sl180 Sl181 Sl182 Sl183 Sl184 Sl185 Sl186 Sl187 Sl188 Treatment of Recurrent Hepatitis C After Living Donor Liver Transplantation Motoshige Nabeshima, Koichi Tanaka, Tsutomu Chiba The Risk of Acute Rejection in Patients Treated with Pegylated Interferon and Ribavirin for Recurrent Hepatitis C Post Liver Transplantation Nassim Elhajj, Nickolas Kontorinis, Kaushik Agarwal, Myron Schwartz, Sasan Roayaie, Thomas D. Schiano Switching from Peg-Interferon ol-2b to an Escalating Peg-Interferon ~-2a Regimen for Recurrent Hepatitis C Post Liver Transplantation May Improve Virological Response and Tolerability Nickolas Kontorinis, Nassim Elhajj, Kaushik Agarwal, Sasan Roayaie, Myron Schwartz, Thomas D. Schiano Patient and Liver Graft Survival in Solitary Liver Transplantation as Compared to Combined Liver-Kidney and Serial Liver and Kidney Transplantation Jasmohan S. Bajaj, Maureen A. McBride, Katarina Anderson, Kia Saeian Elevated Serum Creatinine Immediately After OLT Portends Chronic Renal Insufficiency Kiran Bambha, W. Ray Kim, Rachel Pedersen, Terry Therneau, Walter Kremers, E. Rolland Dickson Long Term Effect of Sirolimus Salvage for Chronic Calcineurin Inhibitor Induced Nephrotoxicity in Liver Transplant Recipients Satheesh Nair, Ari Cohen, George Loss, James Eason Quality of Life After Liver or Combined Liver-Kidney- Transplantation in Patients with Advanced Polycystic Liver-(Kidney)-Disease Gabi Kirchner, Tobias Cantz, Christoph Terkamp, Siegfried Wagner, Hannelore Barg-Hock, Kinan Rifai, Bjocrn Na>ha~. Christian Strassburg, Michael Winkler, Juergen Klempnauer, Michael P. Manns Reported Prevalence of and Survival of Patients with Hepatic Encephalopathy (HE) Have Not Changed with MELD Implementation Jasmohan S. Bajaj, Kia Saeian Predictive Factors for Survival in Elderly Liver Transplant Patients Ye H. Oo, Bridget Gunson, Peter Nightingale, Charles Imber, David Mutimer, Geoffrey Haydon Lack of Correlation Between Pretransplantation MELD Score and Outcome of Liver Transplantation Amitabh Suman, William Carey, David Barnes, Nizar Zein The Efficacy of Bridging Therapy on Survival Following Liver Transplantation for Hepatocellular Carcinoma Hideo Yoshida, Tomoaki Kato, David M. Levi, Juan R. Madariaga, Jang I. Moon, Seigo Nishida, Gennaro Selvaggi, Eugene R. Schiff, Andreas G. Tzakis Increased Incidence of Biliary Complications following Liver Transplantation in Cystic Fibrosis Aaron J. Shiels, Sreenivasa S. Jonnalagadda, Ross W. Shepherd De novo Malignancies and Tobacco Abuse Following Liver Transplantation Louis G. Seele, Mohammad K. Ismail, Claudio Tombazzi, Martha J. Garner, Bradford Waters Cirrhosis After Orthotopie Liver Transplantation (OLT) in the Absence of Disease Recurrence Moataz S. Seyam, Bridget K. Gunson, James M. Neuberger, Stefan G. Hubscher Denotes DDW Poster of Distinction P-123

13 POSTER SESSIONSmCLINICAL SCIENCE I $1189 Predictors of Alcohol Recidivism in an Alberta Transplant Registry Puneeta T. Grover, Gian Jhangri, Norman Kneteman, James Shapiro, David Bigam, Andrew Mason, Klaus Gutfreund, Mang Ma, Cindy Hoekstra, Vincent Bairt AM-5:00 PM Hall F S U N D A Y MAY 16 Sl190 Sl191 $1192 $1193 Sl194 $1195 Sl196 Sl197 8 $1198 $1199 $1200 Donor Steatosis and Recipient BMI Affect One-Year Outcome When Using Expanded and Traditional Donors Jonathan Benson, A. J. Tector, Rong Qi, L. Lumeng, John A. Fridell, D. Rouch, M. Milgrom, L. 5uthat, Hwan Yoo, Naga Chalasani, Paul Kwo Recurrence of Hepatocellular Carcinoma After Liver Transplantation: A Single Center Experience Joanie Salotti, Brian Felland, Yuko Kono, Robert Mattrey, Steve Rose, Cynthia Behling, Elliot Alpert, A. Khanna, Marquis Hart, Katherine Hall, Fatma Barakat, Tarek Hassanein Predictive Factors of Outcome After Liver Transplantation in Patients with Liver Cirrhosis and Hepatocellular Carcinoma Manuela Merli, Giorgia Nicolini, Federica Gentile, Giada Indrio, Massimo Iappelli, Massimo Rossi, Pasquale Berloco, Ugo Di Tondo, Andrea Onetti Muda, Stefano Ginanni Corradini, Francesco Nudo, Adolfo F. Attili Survey of Steroid Use After Liver Transplantation in United States Hwan Y. Yoo, Sunil Ramrakhiani Liver Transplantation for Hepatocellular Carcinoma: A Single Center Experience of the MELD Impact Mankanwal Sachdev, Vijayan Balan, Jose Hernandez, Sorin Petre, Pratima Sharma, Hector Rodriguez-Luna, Jorge Rakela., Hugo Vargas, Thomas Byrne, David Douglas, David Mulligan, Adyr Moss, Kunam Reddy. Growth and Dietary Patterns in Children After Liver Transplantation Timothy A. Sentongo, Roopa Seshadri, Ann Quinn, Estella Alonso Hepatitis C in Living-Related Liver Transplantation Recipients: Are Outcomes Worse? Dean L. Chen, Nicolle Baker, Robert Smith, Leslie Lilly, Nigel Girgrah Obstacles in Adult-to-Adult Live Liver Donation: The Johns Hopkins Experience S. S. Solga, K. D. Fairbanks, C. K. Cohen, M. Rupert, Andrew S. Klein, Louis Arrazola, Rudra Rai Immediate Hospital Outcomes Following Live-Donor Hepatectomy John Donovan, Hassan Zaghla, Jeffery Kahn, Tse-Ling Fong, Linda Chan, Linda Sher, Rod Mateo, Gagandeep Singh, Nicholas Jabbour, R. R. Selby, Yuri Genyk Surgical Complications in Right Lobe Living Donor Liver Transplantation: A Single Center Experience Manuel I. Rodriguez-Davalos, Gabriel E. Gondolesi, Rafael Maurette, Giovanni Varotti, Sasan Roayaie, Sukru Emre, Myron Schwartz, Charles Miller Expression of Cytokiues That Can Activate NF-KB During Liver Regeneration in Living Liver Transplantation Donors Yumi Yamaguchi, Katsuya Shiraki, Yutaka Yamanaka, Yukiko Saitou, Tomoyuki Kawakita, Norihiko Yamamoto, Kazushi Sugimoto, Kazumoto Murata, Takeshi Nakano, Shugo Mizuno, Kentarou Yamagiwa, Hajime Yokoi, Shinji Uemoto Sponsored by: AGA; Liver and Biliary CLINICAL BILIARY TRACT DISORDERS $1202 $1203 $1204 $1205 $1206 $1207 $1208 S1209 $1210 $1211 $1212 Immunoelectronic Expressions of Intercellular Adhesion Molecules and Lymphocyte Function-Associated Antigens on Cannals of Hering and Bile Ductules in Primary Biliarry Cirrhosis Hiroaki Yokomori, Masaya Oda, Hiromasa Ishii What Hides Behind Isolated Biliary Strictures? Cynthia Levy, Paul Angu[o, Keith D. Lindor Expression of Toll-like Receptor in the Biliary Epithelial Cell Lines and Human Gallbladder Tissues Yun-Ju Jo, Ho-Soon Choi, Na-Young No, Oh Young Lee, Dong-Soo Han, Joon-Soo Hahm, Seong-Sam Back, Christopher E. Savard, Sum P. Lee Endoscopic Balloon Sphincter Dilation (Sphincteroplasty) vs Sphincterotomy For Common Bile Duct Stones: A Cochrane Collaboration Meta-Analysis Benjamin M. Weinberg, Waleed Shindy, Simon K. Lo Does Underlying Inflammatory Bowel Disease (IBD) Influence Patient Outcomes in Primary Sclerosing Cholangitis (PSC)? Satyananda Kumar Vuddagiri, Renee France, Richard Kozarek Does the Absence of Gallstones or the Presence of Irritable Bowel Syndrome Predict Symptom Response of Biliary Pain to Cholecystectomy? Bennett Hooks III, Christopher Lind, Howard Mertz Systematic Appraisal of the Role of Metallic Endobiliary Stents in the Treatment of Benign Extra-Hepatic Biliary Stricture Priyantha Siriwardana, Ajith K. Siriwardena Prediction of the Prognosis in Gallbladder Carcinoma by Mucin and p53 Immunohistochemistry Naoki Muguruma, Maynko Takagawa, Yoshitaka Imoto, Yasunori Sato, Rika Aoki, Seisuke Okamura, Ichiro Shimizu, Susumu Ito Implications of Bile Duct Morphology in Patients with Primary Sclerosing Cholangitis Peter N. Meier, Martin Krueger, Tina Nietzschmann, Michael P. Manns The Laparo-endoscopic "Rendez-Vous" for the Treatment of Cholecysto-choledocolithiasis: It Reduces Endoscopic Time and Pancreatic Damage if Compared to ERCP Gaetano La Greca, Michele Di Blasi, Manuela Di Stefano, Carmelita Marcantoni, Francesco Barbagallo, Saverio Latteri, Rosario Bonaccorsi, Domenico Russello Frequent Reflux of Intestinal Content Contributing to the Occlusion of Biliary Stents - Histological and Immunochemical Evidence Hongjun Zhang, Tat-Kin Tsang, Willis Parsons, Colleen Flanigan, Xiangwen Meng, Michael Goldberg Persistent Gallbladder Sludge: Long Term Follow Up After Successful Oral Bile Acid Dissolution Carlos Guma, Marcelo Thome, Luis Viola, Daniel Vainberg P-124 ~ Denotes DDW Poster of Distinction

14 POSTER SESSIONS--CLINICAL SCIENCE AM-5:00 PM sponsored by: Clinical Practice HEALTH SERVICES.~$1213 Hall F The Outpatient Experience of GERD Patients in US: An Analysis of the National Ambulatory Medical Care Survey Steve J. Niemcryk, Sandra Joshua-Gotlib, Doug Levine $1227 k.) S1228 $1229 The Majority of People with Colorectal Cancer Do Not Have Adequate Lymph Node Retrieval; A Population Based Study Daniel J. Virnig, Beth A. Vimig, David A. Rothenberger, Nancy N. Baxter A Model for the Treatment of Hepatitis C by Primary Care Physicians Adelaida Ortiz, Pablo J. Costas, Esther A. Torres, Vanessa Velazquez Predictive Factors of Successful Liver Transplant (OLT) in a Population with Limited Access Federico Gregory, Maria Vazquez, Hector Lozano, Arleen Guzman, Angel Alsina, Esther A. Torres, Cynthia E. Rivera $1214 $1215 $1216 $1217 S1218 $1219 $1220 $1221 $1222 $1223 S1224 $1225 S1226 Medical Service Use & Expenditures in Patients with Gastroesophageal Reflux Disease: An Analysis of Data from the Medical Expenditure Survey, Steve J. Niemcryk, Xiongkan Ke, Sandra Joshua-Gotlib, Doug Levine Acid-Related Gastrointestinal Disorders in the United States between 1989 and 2001: Prevalence, Characteristics, Reasons for Visits, and Use of Acid Reducing Therapy Patrick D. Meek, David A. Mott, Donald J. Brust, Eric A. Gaumnitz Validation of a Clinical Prediction Model and Determinants of Referral Practice in a Rapid Access Upper GI Cancer Service (Raugics) Neff Kapoor, Richard Sturgess, Keith Bodger Cost of Paediatric Inflammatory Bowel Disease: One Year Prevalence Cohort Study Asish Bassi, Zahabiyah Bassi, Mark Dalzell, David Casson, Keith Bodger The Effect on Health Care Resources of lnfliximab Use in Crohn's Disease Derek Jewell, Christopher Probert, Alan Lobo, Jack Satsangi, Alastair Forbes, Subrata Ghosh, Jon Shaffer A Nurse-Led Open Access Service for Patients with Inflammatory Bowel Disease Improves Patient Care in a UK District General Hospital Catherine PearsorL Kieran J. Moriarty, George R. Lipscomb Osteoporosis in Chronic Liver, Inflammatory Bowel and Coeliac Disease: Applying the Guidelines Emma Donaldson, Alex Simon, Karen Shepherd, Kieran J. Moriarty, George R. Lipscomb, Catherine Pearson Doctor-Patient Interaction for Irritable Bowel Syndrome: A Systematic Perspective Surinder K. Dhaliwal, Richard H. Hunt Racial/Ethnic Disparities in Colorectal Cancer at a University Based Hospital Mariam Shahbazian Sauer, Reena Salgia, Karen E. Kin Predictors of Adherence with Scheduled Colonoscopy Reid Ness, Deborah Welch, Barbara Zhao, Robert Dittus, Margaret Hargreaves Physician Barriers to Colorectal Cancer Screening in the Hispanic Population in Chicago Blythe Bartos, Karen E. Kin Combined Patient and Physician Intervention To Increase Colorectal Cancer Screening M. Rosario Ferreira, Nicolle Gorby, Nancy Dolan, Marian Fitzgibbon, Terry Davis, Dachao Liu, Alfred Rademaker, Charles Bennett Comorbid Illness and Colorectal Cancer Screening Deborah A. Fisher, Christopher Martin, Joseph Galanko, Robert S. Sandler, Dawn Provenzale AM-5:00 PM Hall F Sponsored by: Esophageal, Gastric and Duodenal Disorders BARRETT'S ESOPHAGUS: DIAGNOSIS AND MANAGEMENT Assessment of Genetic Defects in Patients with S1230 Complete versus Partial Ablation After Photodynamic Therapy (PDT) for Barretts Esophagus Kenneth K. Wang, Navtej Buttar, Loui,-Michel Won Kcc Song, kori Lutzke, Sarah Papenfus>, Shannon Knight. Kc\ ht Hailing, Marlys Anderson Aberrant Promoter Methylation Silences Secreted- S1231 Frizzled Related Protein Genes and Occurs Early During Neoplastic Progression of Barrett's Esophagus Hongzhi Zou, Jonathan J. Harrington, Julian R. Molina. Nea] K. Osborn, Lawrence J. Burgart, Kristic K Klau Da\ kl A. Ahlquist Does the Length of the Columnar-I_ined Oesophagus S1232 (CLO) Change with Time'? Piers A. C. Gatenby, Christine P J. Cargill, lame> R Ramus, Anthony Watson Does Digital Image Analysis Improve Cytological S1233 Diagnosis in Barretts Esophagus? Kenneth R. Wang, Rodney Pacifico, Navtej S. Buttar, Louis- Michel Wong Kee Song, Lori Lutzke, Sarah Papenfuss, Christine Lohse, Thomas Sebo Serum Fasting Level of Gastrin-17 is Low in Patients S1234 with Long-Segment Barrett's Esophagus Pentti Sipponen, Matti Vauhkonen, Timo Helske, Ilpo Kaariainen, Matti Harkonen Endoscopic Surveillance for Barretts Oesophagus: The S1235 Patients Perspective Amul EL-Agib, Imtiyaz Mohammed, Brian T. Cooper, Nigel Trudgill Significance of Basal Crypt Dysplasia-Like Atypia with $1236 Surface Maturation in Barrett's Esophagus Lesly D. Lomo, Patricia Blount, Cafissa Sanchez, David Cowan, Kamran Ayub, Brian Reid, Robert Odze Immunostaining for AMACR is Useful in Distinguishing $1237 Reactive from Dysplastic Epithelium in Barrett's Esophagus Russell K. Dorer, Jonathan Glickman, Patricia L. Blount, Carissa Sanchez, David Cowan, Kamran Aynb, Brian Reid, Robert J. Odze Denotes DDW Poster of Distinction P-125

15 POSTER SESSIONS--CLINICAL SCIENCE I $1238 Is Alcian Blue Staining Useful in the Diagnosis of Barrett Esophagus? Mamoun Younes, Atilla Ertan, Gulchin Ergun, Ray Verm, Margaret Bridges, Karen Woods, Frank Meriano, Carl Schmulen, Ronald Colman, Craig Johnson, Alberto Barroso, Jim Schwartz, Daniel Ball, John McKechnie, Juan Lechago AM-5:00 PM Hall F ~ Morfal Convention Center S U N D A Y MAY 16 $1239 $1240 $1241 $1242 $1243 $1244 $1245 $1246 $1247 S1248 $1249 $1250 Optimization of Photodynamic Therapy for Barrett's Esophagus: Treatment Efficacy and Stricture Incidence as a Function of Light Dose Mary N. Phan, Masoud Panjehpour, Bergein F. Overholt Barrett's Esophagus at a Tertiary Care Center: Effect of Age on Incidence and Prevalence of Dysplasia and Adenoearcinoma Jason M. Guardino, Farah Khandwala, Joel E. Richter, Gary W. Falk Reflux Esophagitis and Barrett's Metaplasia After H. Pylori Eradication - A Prospective, Controlled Study Pavel Skok, Igor Krizman, Marija Skok High Resolution Zoom Chromoendoscopy to Detect Dysplasia in Barrett's Esophagus Venkatraman Sankara Raman, Neville Krasner, Krish Ragunath, Mustafa Haqqani What is the Positive Predictive Value of Endoscopy for BE? Nicholas J. Shaheen, Beth Lynn Hocutt, Sarah M. Schmitz, Kate R. Lawrence Sensitivity and Specificity Required for Cost-effective Biomarkers Predicting Development of Esophageal Adenocarcinoma Joel H. Rubenstein, Nimish B. Vakil, John M. Inadomi Effect of Esomeprazole on Intragastric and Intraesophageal ph in Patients with Barrett's Esophagus Stuart Spechler, Prateek Sharma, Barry Traxler, Douglas Levine, Gary Falk Establishing Criteria for Subsquamous Barrett's Dysplasia: A Study of 74 Patients Puja Verma, Shari Taylor, Mary Bronner Metaplasia at the Junction: Before vs. After Ablation Therapy for Barrett's Gareth Dulai, W. M. Weinstein, Richard Sampliner, Dennis M. Jensen, G. Cortina Referral Source is Associated with Outcome in Barrett's Esophagus Nicholas J. Shaheen, Beth Lynn Hocutt, Sarah M. Schmitz, Kate R. Lawrence, Joseph A. Galanko Cost-Effectiveness of Flow Cytometry in Screening and Surveillance of Patients with Chronic Gastroesophageal Reflux Disease Lauren B. Gerson, Peter Groeneveld, Peter Rabinovitch, Patricia Blount, Brian Reid Ursodeoxycholic Acid (UDCA) Increases Proliferation and Does Not Show Promise as a Chemoprevention Agent in Barrett's Esophagus Peyman Sahbaie, Peter Siersema, Sumita Sood, Baljeet Kaur, Alan F. Hofmann, George Triadafilopoulos Sponsored by: Esophageal, Gastric and Duodenal Disorders CLINICAL EFFECTS OF HELICOBACTER TREATMENT Serum Antibodies to Helicabacter Pylori and Its Heat $1251 Shock Protein 60 Correlate with the Response of Gastric Mucosa-associated Lymphoid Tissue Lymphoma to Eradication of H. Pylori Ryuta Takenaka, Hiroyuki Okada, Motowo Mizuno, Chiho Makidono, Shin-lchiro Hori, Akiko Fu3iwara, Tadashi Yoshino, Kenji Yokota, Keiji Oguma, Yasushi Shiratori Effect of Helicobacter Pylori Eradication in Patients with $1252 Chronic Idiopathic Thrombocytopenic Purpura -A Randomized Controlled Trial Takayoshi Suzuki, Masashi Matsushima, Takayuki Shirai, Tetsuya Mine Long Term Helicobacter Felis Infection in the C57BL/6 $1253 Mouse- Natural History and Effects of Eradication Therapy on Progression of Disease Xun Cai, Calin Stoicov, Hanchen Li, Jean Marie Houghton Gastric Cancer Discovered After Successful H. pylori $1254 Eradication in Japan Tomoari Kamada, Ken Haruma, Kazuhiko Inoue, Hiroaki Kusunoki, Jiro Hata, Yuzuru Kawamura, Masanori Ito, Shinji Tanaka, Kazuaki Chayama Long Term Effects of Helicobacter pylori Eradication On $1255 L-Dopa Absorption In Parkinson' s Disease Patients Antonio Pietroiusti, Paolo Stanzione, Andrea Magrini, Andrea Bergamaschi, Livia Brusa, Alberto Galante Long-term Effect of H. pylon Eradication on the S1256 Reversibility of Acid Secretion in Patients with Profound Hypochlorhydria Katsunori Iijima, Hitoshi Sekine, Tomoynki Koike, Shuici Ohara, Tooru Shimosegawa Development of Gastric Cancer After Successful $1257 Eradication Therapy of Helicobacter Pylori by Long-Term Prospective Study Shunsuke Takata, Masanori Ito, Shinji Tanaka, Shirt Oka, Hiroyuki Ueda, Yasuo Egi, Hirohisa Kai, Atsunori Sasaki, Hiroshi Masuda, Sunjin Kim, Yoshitaka Ueno, Yasuhiko Kitadai, Tomoari Kamada, Ken Haruma, Kazuaki Chayama Characteristic of Helicobacter Pylori Induced Gastritis $1258 and Effect of H, Pylori Eradication in Patients with Chronic Idiopathic Thrombocytopenic Purpura- Comparing to Patients with Peptic Ulcer Takafumi Ando, Tomoyuki Tsuzuki, Tomokazu Mizuno, Masaaki Minami, Kenji Ina, Kazuo Kusugami, Emad E1- Omar, Michio Ohta, Hidemi Goto Dyspepsia Prescribing by Primary Care Physicians $1259 (PCP) - The Impact of an Open Access Urea Breath Test Service Kathleen Bennett, Humphrey O'Connor, Orla Thornton, Mark Dobson, Martin Buckley, Colm O'Morain, Asghar Qasim, John Feely Morphological Changes in Gastric Neoplasms After $1260 Eradication Therapy of Helicobacter Pylori in a Short- Term Follow-up Masanori Ito, Shinji Tanaka, Shirt Oka, Shunsuke Takata, Yasuo Egi, Hiroyuki Ueda, Sunjin Kim, Hirohisa Kai, Atsunori Sasaki, Hiroshi Masuda, Yasuhiko Kitadai, Tomoan Kamada, Ken Haruma, Kazuaki Chayama P-126 ~ Denotes DDW Poster of Distinction

16 " POSTER SESSIONS--CLINICAL SCIENCE ~r ix S1261 ~ ~: S1262 " S1263 S1264 :~ St265 C' Onset of New Life Habit Diseases by H. Pylori Eradication S 1273 Tomoari Kamada, Ken Haruma, Kuniaki Sugiu, Hiroaki Kusunoki, Jiro Hata, Yuzuru Kawamura, Masanori Ito, Shinji Tanaka, Kazuaki Chayama The TETRA Study: A Prospective Evaluation of Helicobacter Pylori Test-and-Treat Strategy on 736 $1274 Patients in Clinical Practice Javier P. Gisbert, Xavier Badia, Montse Roset, S. Khorrami, J. M. Pajares Is Lymphocytic Duodenitis a Marker for Refractory Non- S1275 Ulcer Dyspepsia in Helicobacter Pylori Gastritis? Sanjay K. Reddy, Thomas Park, Shriram Jakate, All Keshavarzian A History of a Symptomatic Helicobacter Pylori-Related Disease in an Adult 1st Degree Relative Increases the Risk of UGI Symptoms in Their Children Yoshiko Nakayama Usefulness of Helicobacter pylori Eradication in the Prevention of Recurrent Peptic Ulcer Bleeding. A Cost- Effectiveness Analysis Xavier Calvet, Emili Gene, Javier P. Gisbert, Merce Guell '. 8,00 AM-5:00 PM Hall F Sponsored by: Esophageal, Gastric and Duodenal Disorders DIAGNOSIS OF HELICOBACTER PYLORI Minimally Invasive Reliable and Rapid Non-Endoscopic $1266 Method to Obtain Helicobacter Pylori Cultures David Y. Graham, Mayumi Kudo, Rita Reddy, Antone R. Opekun Systematic Review of the Efficacy of the Stool Antigen $1267 Test in the Detection of H. pylori Before and After Treatment in Adults and Children Helen H. Lantz, Susan Partington, Nimish B. Vakil Helicobacter Pylori Stool Antigen Test Is Not Reliable in : ~51268 Patients with Bleeding Peptic Ulcers Hwai J. Lin, I. C. Sun, Wen C. Lo Is the Presence of Helicobacter Species in the Liver A $1269 Risk Factor for the Evolution of HCV-Related Liver ~ ~ Disease? Laurent Castera, Marcia Rocha, Brigitte LeBail, Corinne Ascencio, Victor de Ledinghen, Pierre-Henri Bernard, Christophe Laurent, Marie-Edith Lafon, Maylis Capdepont, Patrice Couzigou, Paulette Bioulac-Sage, Charles Balabaud, Francis Megraud, Armelle Menard Oral Cavity, a Reservoir for Gastric Helicobacter pylori;a $1270 Prospective Controlled Study with Special Reference to Gastroesophageal Reflux Yong Chan Lee, Sang-Seob Lee, Jong-Hoon Choi, Jae Hee Pyo, Chong-Youl Kim, Jin-Kyung Kang Diagnosis of Helicobacter Pylori Infection by Stool S1271 Antigen Determination. A Systematic Review Javier P. Gisbert, J. M. Pajares S1276 $1277 S1278 S1279 S1280 S1281 S1282 S1283 $1284 $1285 Organic Acids Do Not Have the Same Effect on H. pylori Urease Activity in vivo Despite Having the Same Concentration and ph Aamer Agha, Antone R. Opekun, Suhaib Abudayyeh, David Y. Graham Identification of Helicobacter Pylon DNA from Food Sources by a Novel Multiplex PCR Assay Xiangwen Meng, Hongjun Zhang, Tat-Kin Tsang, Jeremy Law Autofluorescence and 5-ALA-Induced Fluorescence of Helicobacter pylori (HP) in Human Gastric Tissue for Non-Invasive in vivo Diagnostics Clive H. Wilder-Smith, Daniel Schindler, Marie Wilson, Friedrich Meister, Petra Wilder-Smith Accuracy of a Low Dosage of 13C Urea for Diagnosis and Monitoring Helicobacter Pylori (HP) Chiara Ricci, Luigi Gatta, Andrea Tampieri, Federico Perna, Mario Miglioli, Dino Vaira Role of Non-lnvasive Diagnostic Methods for Helicobacter Pylori (HP) Infection in Patients with Atrophic Body Gastritis (ABG) Edith Lahner, Dino Vaira, Natale Figura, Federico Perna, Giancarlo D'Ambra, Amelia Pasquali, Gianfranco Delle Fave, Bruno Annibale The Culture of Helicobacter Pylori from Frozen Gastric Biopsy Sample Using New Rapid Urease Test Pum-Soo Kim, ]in-won Lec, Jung I1 Lcc, '~cok Ic,~/<, K\c Sook Kwon, Don Haeng Lee. I I>ung Gil Ki~xl. Yong \\o,,~l Shin, Young Soo Kim,.Jongwook Lee, Euyl HycoK Jill Evaluation of Three Different Tests for the Detection of Stool Antigens to Diagnose H. pylori lndction in Patients with Upper Gastrointestinal Bleeding {UGIB) Javier p. Gishert, M. Trapcro, Xa\'icr Cal\ut. Juan I ui, Mendoza, M. Quesada, M. Guell, J M Palates Is There Any Relation Between Hclicobacler priori Infection and Duodenal Iron Transporters? Yun-Ju Jo, Dong-Soo Han. Eun-kyung Klm. loon Soo Hahm, Young-gook Park. Tae Hun Kim. /c~n I lv ]or Prospective Trial of Hclicobactcr pylori Stool Antigen Testing Frank Weilert, Shamsul Islam, Anthony C. Smith Comparison Between 15 and 30 Minute Sampling Intervals in C-Urea Breath Testing Rachel Cooney, Liz Ellis, Deirdre Brady, Gerald Cox, Martin Healy, Carol Goulding, P. W. N. Keeling Serum Pepsinogens as an Early Diagnosis of H. Pylori Eradication Naohito Shirai, Takahisa Furuta, Mitsushige Sugimoto, Masayoshi Kajimura Light Meal Decreased False-Positive in the 13c-Urea Breath Test for the Diagnosis of Helicobacter Pylori Infection Takuji Yamasaki, Keiichiro Kume, Masahiro Yamasaki, lchiro Yoshikawa, Makoto Otsuki Comparison of a Novel Multiplex PCR and Histology Method for the Diagnosis of H. Pylori Xiangwen Meng, Hongjun Zhang, Tat-Kin Tsang Helicobacter Pylori Infection Increases Heart Burn Symptom in Japanese Younger Generation Yutaka Kondo, Takashi Joh, Tadayuki Oshima, Keisuke Itoh, Satoshi Tanida, Hiromi Kataoka, Makoto Sasaki, Makoto ltoh Denotes DDW Poster of Distinction P-127

17 POSTER SESSIONSmCLINICAL SCIENCE AM-5:00 PM Hall F S1297 Comparison of Two Management Strategies for H. pylori Treatment: A Clinical Study and a Cost Effectiveness Analysis Xavier Calvet, Dritana Marko, Julio Ducons, Jordi Guardiola, Llucia Tito, Felipe Bory Sponsored by: Esophageal, Gastric and Duodenal Disorders HELICOBACTER TREATMENT AND ANTIMICROBIAL RESISTANCE $1298 Is the Additional Acid Suppression Therapy After Helicobacter pylori Eradication Necessary in the Treatment of H.pylori Positive Peptic Ulcer Disease? Gwang H. Balk, Jin B. Kim, Dong J. Kim, Yo A. Sub, Chang S. Choi S U N D A Y MAY 16 Famotidine Increases the Cure Rates of Helicobacter S1286 Pylori Infection by a Triple Therapy in Patients with the Homozygous Extensive Metabolizer Genotype of CYP2C 19 Keisuke Okudaira, Takahisa Furuta, Naohito Shirai, Soichiro Miura Treatment with 4 Times Daily Dosing of Lansoprazole $1287 or Rabeprazole plus Amoxicillin As a Second Line Therapy After Failure of Eradicaion of H. Pylori by Usual PPI Based Therapies Takahisa Furuta, Naohito Shirai, Mitsushige Sugimoto, Kyoichi Ohashi, Takashi Ishizaki Antibacterial Effect of Glycine on Helicobacter Pylori in $1288 vitro Masaaki Minami Individualized Treatment Strategy for the Cure of H. S1289 Pylori Infection Based on the Susceptibility of H. Pylori to Antibiotics and the Cyp2c19 Genotype Status of the Patients Takahisa Furuta, Naohito Shirai, Mitsushige Sugimoto, Masayoshi Kajimura, Kyoichi Ohashi, Takashi Ishizaki Activities and Mechanisms of Proton Pump Inhibitors $1290 Against Helicobacter Pylori Jianzhong Zhang, Yin Yin, Lihua He, Xiaomei Yan Rescue Therapy with Rifabutin After Multiple H. Pylori $1291 Treatment Failures Javier P. Gisbert, Luis. Bujanda, Xavier Calvet, Javier Gisbert, S. Marcos, J. M. Pajares Impact of H. pylori Infection and Acid Blockade by $1292 Lansoprazole on Clarithromycin Bioavailabilty Rodrigo Ortiz, Silvana Calafatti, Luiz Moraes, Maristela Deguer, Christina Ecclisasto, Marco Marchioretto, Gilberto Bernasconi, Jose Pedrazzoli Jr. Helicobacter pylori Antibiotic Resistance in Canadian $1293 Populations Linda Best, Geraldine Cooper-Lesins, David Haldane, Sander Veldhuyzen van Zanten Rabeprazole-Based vs. Omeprazole-Based Short-Term $1294 Triple or Quadruple Therapy for Eradication of Helicobacter pylori Infection: A Randomized Paralleb Controlled Study Dadao Jing, Xing-Peng Wang Rabeprazole/Levofloxacin Based Triple Therapy as a S1295 Salvatage Treatment After Failure of H. Pylori Eradication with Standard Regimens Paolo Orsi, Ovidio Pinazzi, Giovanni Aragona, Francesco Di Mario The Efficacy of Omeprazole/Esomeprazole-Based First- $1296 Line and Rescue Therapies for Treatment of Helicobacter Pylori Infection Is Not Affected by Polymorphisms of Cytochrome P450-2C19 Christian.Kirsch, Wulf Schneider-Brachert, Dana Grossmann, Stefan Ebert, Soeren Schlichting, Regine Birngruber, Andrea Morgner, Ahmed Madisch, Manfred Stoke, Norbert Lehn, Stephan Mieblke S1299 $1300 S1301 $1302 $1303 $1304 S1305 $1306 $1307 S1308 Efficacy of Low Dosage Proton Pump Inhibitors in PPIg AC Helicobacter Pylori Eradication Therapy Takashi Kawai, Kohei Kawakami, Kazuo Takei, Taku Kudo, Takao Itoi, Fuminori Moriaysu, Yuu Takagi, Tatsuya Aoki, Emiko Rinbara, Masahisa Noguchi, Masanori Sasatsu Efficacy, Adverse Events and Adherence Related to First-Line Anti-Helicobacter pylori Quadruple Therapies: A Meta-Analysis Lori A. Fischbach, Sander van Zanten, John Dickason The Efficacy of Esomeprazole Based Triple Therapy and Low-Dose Clarithromycin Triple Therapy for Helicobacter Pylori(HP) Kyu Chan Huh, Toe Hee Lee, Young Woo Kang, Yong Woo Choi, Yeui Huyck Lira First-Line Treatment for Helicobacter Pylori Eradication: Levofloxacin/Azithromycin-Based Strategies Enrico C. Nista, Marcello Candelli, Lucia Fini, Immacolata A. Cazzato, Rosalba Finizio, Cristiano Lauritano, Giorgia Di Gioacchino, Laura Tanturri, Giovanni Cammarota, Giovanni Gasbarrini, Antonio Gasbarrini Novel Bismuth-Metronidazole-Tetracycline (BMT) Triple-Layer Tablet for Treatment of Helicobacter Pylori David Y. Graham, Antone R. Opekun, Genevieve Belson, Hala T. E1-Zimaity, Marilyn R. Carlson Stable Gastric Pentadecapeptide BPC 157 Studied for Inflammatory Bowel Disease (PLD116, PL14736, Pliva) Inhibits Helicobacter Pylori and Enteropathogenic E. Colli Proliferation in Vitro Branko Turkovic, Predrag Sikiric, Sven Seiwerth, Stjepan Mise, Tomislav Anic, Marijan Petek, Rudolf Rucman Mechanisms of Tetracycline Resistance in Helicobacter pylori: Decreased Membrane Permeability and Mutations in 16S rrna Encoding Genes Jeng Yih Wu, M. Lee, Rita Reddy, W. M. Wang, David Y. Graham, Dong H. Kwon Evaluation of a Fluorescent in-situ Hybridization Method (seafast ) to Simultaneously Identify Helicobacter pylori and Determine Its Sensitivity to Clarithromycin Julie Morris, Alisa Reasonover, Dana Bruden, Alan Parkinson, Michael Bruce, Brian McMahon, Frank Sacco, Douglas Berg Real-Time Detection of 16S rrna Mutations in Helicobacter pylori Conferring Resistance to Tetracycline Erik Glocker, Marco Berning, Monique M. Gerrits, Johannes G. Kusters, Manfred Kist Chronic Respiratory Disease is a Risk Factor for Helicobacter Pylori Clarithromycin Resistance Naoko Tsuji, Yoichi Tanaka, En Yoneda, Itsuro Yutani, Masayuki Iimori, Masatoshi Kudo P-128 ~ Denotes DDW Poster of Distinction

18 POSTER SESSIONS--CLINICAL SCIENCE r ~ i: &O0 AM-5:00 PM Hall F AM-5:00 PM Hall F 4"* i: ~nsored by: Esophageal, Gastric and Duodenal Disorders NON-VARICEAL UPPER GI BLEEDING Acute Coronary Events in Patients with Upper S1309 Gastrointestinal Bleeding: A Prospective Study U David M. lser, Alex J. V. Thompson, Koon K. Sia, Neville =: O D. Yeomans, Robert Y. Chen ii Influence of Geographical Location of Randomized $1310 Controlled Trials (RCTs) on Effectiveness of PPI i Treatment in Ulcer Bleeding: A Post Hoc Analysis of a -~ Cochrane Collaboration (CC) Systematic Review Grigoris I. Leontiadis, Linda McIntyre, Virender K. Sharma, r., Colin W. Howden 3 : Selective Serotonin Reuptake Inhibitors (SSRIs) and $1311 Risk of Upper Gastrointestinal Bleeding: Confusion or Confounding? Yuhong Yuan, Richard H. Hunt!!;: 7 ' A Loading-Dose Regimen (LDR) of Omeprazole- S1312 Immediate Release Oral Suspension (OME-IR SUSP) Increases Bioavailability (Healthy Subjects) and Achieves Rapid Control of Gastric Acidity in Critically Ill Bonnie Hepburn, Yun Hardiman, William O. Frank, Barry Goldlust S1313 Antiinflammatory Therapy with Prednisolone in the Treatment of Bleeding Helicobacter pylori Associated Peptic Ulcers Juergen Bauditz, Maria-Anna Ortner, Abdul A. Taha, Jutta Weber, Herbert Lochs Characteristics of Gastric Antral Vascular Ectasia in $1314 Hemodialysis Patients : Takanori Fukami, Yoshihiro Akashi, Seiichi Ohbayashi ' Is Upper Endoscopy Underutilized in the Setting of Acute Myocardial Infarction and Upper Gastrointestinal Bleeding Sauyu Lin, Richard Konstance, Carlos Micames, Deborah Fisher ~,,. $1316 Efficacy of PPI Treatment for Ulcer Bleeding when Compared with Placebo or an H2-Receptor Antagonist (H2RA): A Sub-Group Analysis from the Cochrane Collaboration (CC) Systematic Review Grigoris 1. Leontiadis, Linda Mclntyre, Virender K. Sharma, Colin W. Howden Outcome of Acute Upper Gastrointestinal Bleeding S1317 (AUGIB) Post-implimentation of a Protocol Based Management in a UK District General Hospital Achuth H. Shenoy, Radhakrishnan Nerukav, David N. Foster, Ravi K. Sharma, Laura J. Quest, Faiyaz Mohammed, Regi George Clinical Factors Inducing Admission in Patients with $1318 Upper Gastrointestinal Bleeding-Not Associated with Portal Hypertension (UGB-NPH) Without Absolute Criteria to Hospitalize Pedro Almela, Miguel Minguez, Ramon Anon, Vicent Hemandez, Belen Herreros, Cirilo Amoros, Vicente Sanchiz, Isabel Pascual, Francisco Mora, Adolfo Benages Sponsored by: Gastrointestinal Oncology COLON CANCER: CLINICAL I Behavioural Differences Between Participants and Non- S1319 participants in Colorectal Cancer (CRC) Screening Graeme P. Young, Stephen Cole, Naomi Roosa, Sarah Mehaffey, Alicia Smith, Adrian Esterman, Janine Severino, Deborah Tumbull Application of a Computer Algorithm for the Evaluation S1320 of Family History Questionnaires in a Screening Program Kenny Chiu, Roger Coron, Marijayne Bushey, Emily Glogowski, Nathan Ellis, Kenneth Offit, Ann Zauber, Sidney J. Winawer Randomized Controlled Trial of the Impact of Intensive S1321 Patient Education on Compliance with Fecal Occult Blood Testing Charlene Stokamer, Craig Tenner, Jhuma Chaudhuri, Eva Vazquez, Edmund J. Bini Diagnosing Small Bowel Tumors with Capsule S1322 Endoscopy Gena M. Cobrin, Robert H. Pittman, Blair S Lewis Retrospective Comparison of Surveillance Intervals After S1323 Colonoscopic Screening on Asymptomatic Japanese Yutaka Yamaji, Shimaro Kondo, Miki Ota, Hirotsugu Watabe, Goichi Togo, Makoto Okamoto, Takao Kawalnc Ryoicbi Wada, Torn Mitsusbima, Masao Omata Comparative Study of Two Fecal Occult Blood Tests in S1324 Patients Undergoing Colonoscopy: A Validation Study Marcia Cruz-Correa, Kathleen Sclnuh=, SaNay Jagannarln Mary Harris, Sergey Kantsevoy, Marshall Bedine, Anthon\ Kalloo Comparison of Clinical Characteristics of Families with S1325 and Without Mismatch Repair Gene Deletions in Hereditary Nonpolyposis Colon Cancer (HNPCC) Prathap Bandipalliam, Judith Balmana, Richard D. Kolodner, Sapna Syngal Use of Fuzzy Modeling to Predict the Risk of Colon $1326 Cancer in HNPCC Patients Rhonda M. Brand, David Jones, Henry T. Lynch, Randall E. Brand, Angel Nickolov, Patrice Watson, Hemant K. Roy C-Kit Gene Mutation Was Not Detected in S1327 Gastrointestinal Stromal Tumors of Neurofibromatosis Type I, and NF1 Gene Mutation Was Not Detected in Sporadic Gastrointestinal Stromal Tumors Kazuo Kinoshita, Seiichi Hirota, Koji Isozaki, Akiko Ohasbi, Toshirou Nishida, Yoko Murayama, Shuusaku Tsutsui, Shinji Tamura, Yasuhisa Shinomura Diagnosis and Analysis of C-Kit Mutation in $1328 Gastrointestinal Stromal Tumors (GISTs) by Endoscopic Ultrasonography-Guided Fine Needle Aspiration Biopsy, and Relationship Between C-Kit Mutation and Tumor Growth Kazuo Kinoshita, Koji Isozaki, Seiichi Hirota, Shuusaku Tsutsui, Takashi Fujimoto, Kenji Watabe, Masanori Nakahara, Yoko Murayama, Tatsuya Kiyohara, Toshirou Nishida, Shinji Tamura, Yasuhisa Shinomura Denotes DDW Poster of Distinction P-129

19 POSTER SESSIONSwCLINICAL SCIENCE S U N D A Y MAY 16 $1329 $1330 $1331 $1332 $1333 $1334 $1335 $1336 $1337 $1338 $1339 S1340 $1341 $1342 $1343 A Novel Educational Strategy to Enhance Internal Medicine (IM) Residents' Familial Colorectal Cancer Risk Assessment and Management Skills Paul Schroy III, Julie Glick, Alan Geller, Angela Jackson, Marianne Prout Association of Colorectal Cancer (CRC) and Subsequent Prostate Cancer David T. Rubin, Dezheng Huo, Hemant Roy Cholecystectomy and Risk of Colorectal Cancer Theresa Shao, Yu-Xiao Yang Colorectal Cancer (CRC)Is Associated with Increased Risk of Subsequent Urologic Malignancy (URC) David T. Rubin, Audrey H. Calderwood, Dezheng Huo Lower Prevalence of Detectable Genomic Instability in Right-Sided Colon Cancers from Blacks Alexie Nguyen, Ryan T. Doctolero, Temitope Keku, Joseph A. Galanko, Akihiro Tajima, Robert S. Sandler, John M. Carethers Effect of Tobacco/Alcohol and Gene Mutated on Extracolonic Cancers in HNPCC Mutation Carriers Ramesh Ashwathnarayan, Patrice Watson, Henry T. Lynch, Hemant K. Roy HNPCC-associated Small Bowel Cancer: Clinical and Genetic Characteristics Karsten Schulmann, Christoph Engel, Tilman Vogel, Constanze Pagenstecher, Hans K. Schackert, Magnus yon Knebel-Doeberitz, Holger Vogelsang, Josef Rueschoff, Wolff Schmiegel, The German HNPCC-Consortium Genomic Rearrangements in MSH2 and MLH1 in Spanish Hereditary Nonpolyposis Colorectal Cancer Patients Sergi Castellvi-Bel, Virginia Pinol, Antoni Castells, Montserrat Mila, Josep Maria Pique, Spanish Gastroenterological Association Molecular Signatures of High and Low Risk Aberrant Crypt Foci in a Mouse Model of Sporadic Colon Cancer Prashant R. Nambiar, Masako Nakanishi, Rishi Gupta, Evelyn Cheung, Ali Firouzi, XiaoJun Ma, Christopher Flynn, Met Dong, Kishore Guda, Rajiv Raja, Luke Achenie, Daniel W. Rosenberg Expression of Cyclooxygenase 2 in Hamartomatous Polyps of Korean Peutz-Jeghers Syndrome Patients Se-Joon Lee, Dae-Hoon Song, Jun-Pyo Chung, Kwan-Sik Lee, Jae-Bock Chung, Sangqn Lee, Jin-Kyung Kang, Soon- Won Hong Gender Disparities in Family History Knowledge in High Risk Colon Cancer Screening Sonia Kupfer, Sarah McCaffrey, Laura de Tar, Karen E. Kim Familial Colorectal Cancer Risk Assessment in Blacks; the Role of Paternal History Sonia Kupfer, Sarah McCaffrey, Laura de Tar, Karen E. Kim Digestive Manifestations of Cowden Syndrome Federico Sopena, Robert F. Wong, Katrina Lowstuter, Angela Schwab, Scott Kuwada, Randall W. Butt Colonoscopy Screening for Colorectal Cancer: A Comparative Study in Italy Nereo Segnan, Bruno Andreoni, Luigi Bisanti, Guido Castiglione, Andrea Ederle, Arnaldo Ferrari, Stefano Gasperoni, Giuseppe Malfitana, Angelo Pera, Serafino Recchia, Mario Rizzetto, Carlo Senore, Patricia Turco A Propsective Study of the Natural History of Low- Grade Dysplasia in Ulcerative Colitis Patients Using Optimum Colonoscopic Surveillance Teresa Brenmall, Michael B. Kimmey, Kris Kowdley, Peter Rabinovitch, Mary Emond, Mary Bronner 8 $1344 $1345 $1346 Clinicopathological Features of Colorectal Cancer Patients According to Level of Microsatellite Instability (MSI).The Significance of MSI-L Tumors Xavier Llor, Spanish Society of Gastroenterology/Oncology Group Identification of Cancer in Lymph Nodes Using Fourier Transform Infrared (FT-IR) Attenuated Total Reflectance (ATR) Spectroscopy. Comparison with Pathology J. S. Shi, Roger D. Soloway, Q.-B. Li, X.-J. Sun, J. S. Wang, Y.-Z. Xu, S. F. Weng, Z. Liu, F. Wang, L.-M. Yang, D.-F. Xu, J.-G. Wu A Quantifiable Fecal Immunochemical Test (FIT) for Hemoglobin Facilitates Balancing Sensitivity with Specificity When Screening for Colorectal Cancer Alicia Smith, Graeme P. Young, Stephen Cole, Joylene Morcom, Howard Chandler, Larry La Pointe AM-5:00 Sponsored by: Imaging and Advanced Technology VIRTUAL ENDOSCOPY, MRI AND CT IMAGING $1347 S1348 $1349 $1350 $1351 $1352 S1353 $1354 P-130 Denotes DDW Poster of Distinction Hall F First French Evaluation of the 3D Real Time Virtual Image in the Practice of Colonoscopy Patrick Faure, George Rateb, Jacques Moreau, Louis Buscail, Jean Escourrou A Comparison of MRI Colonography with Conventional Colonoscopy for the Assessment of Intestinal Inflammation in Patients with Inflammatory Bowel Disease Andreas G. Schreyer, Heiko C. Rath, Ron Kikinis, Markus Voelk, Juergen Schoelmerich, Stefan Feuerbach, Gerhard Rogler, Johannes Seitz, Hans Herfarth Superior Mediastinal and Neck Lymphatic Mapping in Mid- and Lower-Thoracic Esophageal Cancer as Defined by Ferumoxides-enhanced Magnetic Resonance Imaging Satoru Motoyama, Hiroshi Imano, Manabu Okuyama, Yosbihiro Minamiya, Jun-lchi Ogawa Determination of Lingual Myoarchitecture with High Angular Resolution by Diffusion Spectrum Imaging Richard J. Gilbert, Vitaly J. Napadow, Van J. Wedeen Feasibility Study of MRI Based Colonography for Diagnosis and Assessment of Diverticulosis and Diverticulitis Andreas G. Schreyer, Alois Fuerst, Ayman Agha, Ron Kikinis, Karl Scheibl, Markus Voelk, Stefan Feuerbach, Juergen Schoelmerich, Johannes Seitz, Hans Herfartb Magnetic Resonance Cholangiopancreatography Under Secretin Injection for the Diagnosis of Pancreatobiliary Reflux Ryotaro Sakamori, Tomoki Michida, Masahiro Ikeda, Takuya Hosoki Relative Accuracy of Progressive Computed Tomographic System Technology in the Staging of Gastric Cancer Michael Stepbens, Jamie Boyce, Guy Blackshaw, Holly Paris, John Barry, Paul Edwards, Gerald Thomas, Wyn Lewis Pancreatic Volume by Multi-Slice Helical CT Related to Clinical Measures of Pancreatic Function Yuji Nakamura, Susumu Higuchi, Katsuya Maruyama

20 v POSTER SESSIONS~CLINICAL SCIENCE ~1355 $1356 S1357. S1358 S1359 S1360 $1361 'S1362 Colonoscopic Measurements Have a High Correlation to Virtual Colonoscopy Centerline Measurements: Implications for Communication of Information from Radiologist to Gastroenterologist David T. Rubin, Akihiko Okamura, Abraham H. Dachman, Bonnie L. Surma, Hiro Yoshida Feasibility of CT Virtual Endoscopy in Patients with Palliative Esophageal Stent Celine Savoye-Collet, Veronique Maneglia, Emmanuel Ben Soussan, Michel Antonietti, Guillaume Savoye, Jean-Nicolas Dacher Same-Day, Same-Prep CT Colonography (CTC) for Incomplete Colonoscopy Due to Colorectal Cancer (CRC) Tara N. Troy, Abraham H. Dachman, David T. Rubin Cost-Effectiveness Study of CT Colonography Versus Colonoscopy Using Decision Analysis Steven Heitman, Andrew Fong, Stafford Dean, Robert Hilsden, Braden Manns, Joseph Romagnuolo Assessment of Bowel Preparation Efficacy Using Oral Barium in 'Prepless' CT Virtual Colonoscopy Philip Mcandrew, Kapil Kapur, Andrew Swift, Mohammed Karajeh, Paraskevi V. Sakellariou Abdominal MIBl-lmaging for Diagnosis of Gastrointestinal Carcinoma Prior Morphine Administration Arnulf Ferlitsch, Rainer Schoefl, Petra Steindl-Munda, Michael Haefner, Markus Peck-Radosavljevic, Christian Madl, Regina Poetzi, Gudrun Kreuzer, Monika Homoncik, Claudia Weidekamm, Susanne Granegger, Helmut Sinizinger Diagnostic Ability of Virtual Colonoscopy (CT Colonography) with Special Regards to Polyp Morphology Yutaka J. Kawamura, Jun'ich Sasaki, Fumio Konishi Modelling of the 3D Geometry in the Human Rectum Based on Magnetic Resonance Imaging (MRI) Jens B. Frokjaer, Barry P. McMahon, Donghua H. Liao, Asbjorn M Drewes, Hans Gregersen AM-5:00 PM Hall F Sponsored by: Immunology, Microbiology & Inflammatory Bowel Disorders il.ibd DIAGNOSTICS, DISEASE ASSESSMENT, AND THERAPEUTIC MONITORING Rapid Diagnosis of Ulcerative Colitis and Crohns $1363 Disease by the Analysis of Flatus Christopher S. J. Probert, C. E. Garner, Norman Ratcliffe $1364 : $1365 Anti-Saccharomyces Cerevisiae Antibody (ASCA) in Patients with Intestinal Behget's Disease: Relation to Clinical Course Chang Hwan Choi, Sang Kil Lee, Tae Il Kim, Hyun Sook Kim, Won Ho Kim Granulomas Are Associated with Upper GI Involvement and Fistulae but Not with Strictures in Paediatric Crohn Maja Idestrom, Fredrik Granath, Hans Hildebrand, Carlos Rubio, Yigael Finkel $ S1367 S $1369 $1370 S1371 S1372 $1373 $1374 S1375 S1376 Anti-Laminarobioside Carbohydrate Antibodies (ALCA), Detected by a Novel Glycan Microarray Chip Differentiate Between Crohn's Disease and Ulcerative Colitis Patients Iris Dotan, Sigal Fishman, Revital Kariv, Yaara Dgani, Mikael Schwartz, Ari Gargir, Larissa Spector, Zamir Halpern, Nir Dotan Predictors of Acute and Chronic Pouchitis Mohammad A. A1-Haddad, Jean-Paul Achkar, Farah Khandwala, Feza Remzi, Bo Shen, Aaron Brzezinski, Bret Lashner, Victor Fazio, Cleveland Clinic Foundation Inflammatory Transcript Profiles Reflect Onset of Clinical Remission in Patients with Steroid Refractory Crohns Disease (CD) After Treatment with Cyclophosphamide or Infliximab Andreas Stallmach, Thomas Giese, Carsten Schmidt, Bianca Ludwig, Martin Zeitz, Stefan Zeuzem, Stefan Meuer Clinical Significance of Magnifying Endoscopy in the Remission Stage of Ulcerative Colitis Minoru Matsuura, Akiyoshi Nishio, Chiharu Kawanami, Hiroshi Nakase, Hiroyuki Tamaki, Masanori Asada, Kimio Kawasaki, Toshiro Fukui, Hazuki Yoshizawa, Shinya Ohashi, Satoko Inoue, Keiichi Kiriya, Hiroshi Kitamura, Kazuichi Okazaki, Tsutomu Chiba Anal Ultrasound in Evaluating Activity of Perianal Crohn's Disease Alessandra Losco~ Flavio Caprioli, Dario Conic. Piclro Biondetti, Guido Basilisco Capsule Endoscopy in Patients with Crohns DNease and Small Bowel Involvement Distal to the Terminal Ileum, Detected by MR Enteroclysis Cornelia Tillack, Karin Herrmann, Julia Seid~'rer, b/cphan Brand, Maximi[ian Reiscr, Burkhard Gocke, Thoma> Ochsenkuhn Increase of 6-TGN Level After lnfliximab Infusion Has a 100% Predictive Value of Clinical Response in Crohns Disease Xavier Roblin, Francoise Serre Debeauvais, Frederic Heluwaert, Jean-Marc Phelip, Germain Bes_,ard, ~can I u~ Faucheron, Bruno Bonaz In vivo Imaging of Infliximab Induced Apoptosis in Crohn's Disease Patients Jan M. H. Van den Brande, Rod Bennink, Zusanna Detkova, Henri Braat, Niels Steinmetz, Maikel Peppelenbosch, Daan Hommes, Sander van Deventer Clinical and Subclinical Intestinal Inflammation Assessed by the Mucosal Mapping Technique. Studies of Mucosal Neutrophil and Eosinophil Activation in Inflammatory Bowel Diseases and Irritable Bowel Syndrome Gudjon Kristjansson, Per Venge Sr., Lars Loof, Roger Hallgren Infliximab Therapy Is Associated with Early Increase in Lymphocytosis Irrespective of the Clinical or Biological Response Severine Vermeire, Maja Noman, Gert Van Assche, Tibor Hlavaty, Myriam Bueno de Mesquita, Paul Rutgeerts Azathioprine-Induced Nodular Regenerative Hyperplasia (NRH) of the Liver in IBD patients Fady Daniel, Jean-Francois Cadranel, Philippe Seksik, Alain Cazier, Jean-Paul Duong, Marianne Ziol, Pierre Coutarel, Patrick Loison, Raymond Jian, Philippe Marteau Denotes DDW Poster of Distinction P-131

21 POSTER SESSIONS--CLINICAL SCIENCE S U N D A Y MAY 16 S1377 S1378 $1379 $1380 S1381 $1382 $1383 $1384 $1385 $1386 Changes in Activity of Distinct PKC lsoforms Could Explain the Extent of Oxidative Injury & NF-KB Activation in Mucosa of Patients with Inflammatory Bowel Disease (IBD) All Banan, Ece Mutlu, Maliha Shaikh,.Lijuan Zhang, Jeremy Fields, Sri Kommanduri, All Keshavarzian Adsorptive Granulocyte and Monocyte/Macrophage Apheresis versus Prednisolone in Patients with Corticosteroid Dependent Ulcerative Colitis Hiroyuki Hanai, Takayuki lida, Ken Takeuchi, Tatsuo Tanaka, Kotaro Tozawa, Fumitoshi Watanabe, Yasuhiko Maruyama, Masami Yamada, Yasushi Iwaoka, Isao Matsushita, Yoshihiko Satou, Abby Saniabadi Association Between Enhanced Soluble CD40 Ligand and Prothrombotic State in Inflammatory Bowel Disease Ioannis E. Koutroubakis, Angeliki Theodoropoulou, Costas Xidakis, Aekaterini Sfiridaki, George Notas, George Kolios, Elias Kouroumalis Promotor CpG Island Hypermethylation of pl4arf, p15ink4b, and p161nk4a Is Common in Normal and Inflamed Colon of Patients with Long-Standing Ulcerative Colitis Karen V. Winther, Eywin Bruun, Thomas Horn, Per Guldberg, Jorn Brynskov, Vibeke Binder Disease Activity Indices in Ulcerative Colitis Are Able to Objectively Predict Patient-Defined Remission Peter D. R. Higgins, John Mapili, Marc Schwartz, Sheryl Korsnes, Ellen M. Zimmermann Uhrasonograpy with and without Contrast, in the Assessment of Small Bowel Lesions in Crohn's Disease (CD) Nadia Pallotta, Ernesto Tomei, Angelo Viscido, Emma Calabrese, Giustina Milite, Amelia Buffone, Renzo Caprilli, Enrico Corazziari The Edinburgh Colitis Risk Score (ECRS) Aids in the Selection of Patients for Second-Line Medical Therapy/ Surgery in Japanese Cohort of Patients with Acute Severe Ulcerative Colitis (UC) Gwo-Tzer Ho, Nobu Oshitani, Dan Gilpin, Craig Mowat, Robin Prescott, Jack Satsangi Measurement of Anti-neutrophil Cytoplasmic Antibodies (ANCA) in Human Feces as an Indicator of Ulcerative Colitis Daniel F. Sisco, Thomas A. Walker, Paul A. Rufo, James H. Boone Perianal Fistulas in Crohn's Disease Are Not Mainly Colonized by Intestinal Flora R. L. West, C. J. van der Woude, H. P. H. Endtz, M. Ouwedijk, H. Boelens, Johannes Kusters, Ernst J. Kuipers Intraoperative ex vivo Histology-correlated Optical Coherence Tomography in the Detection of Transmural Inflammation in Crohn's Disease Bo Shen, Gregory Zuccaro Jr., Terry Gramlich, Natalie Gladkova, Conor Delaney, Jason Connor, Margaret Kareta, Bret Lashner, Charles Bevins, Felix Feldchtem, Scott Strong, Marlene Bambrick, Patricia Trolli, Victor Fazio $1389 $1390 $1391 $1392. $1393 $1394 S1395 $1396 $1397 S1398 S1399 Cost-Effectiveness Analysis of Fecal Lactoferrin Assay As the Initial Diagnostic Approach to Symptomatic Patients with Ileal Pouch-Anal Anastomosis Mansour A. Parsi, Jeffrey J. Ellis, Bret A. Lashner A Prospective Study of Implementation of the AGA Osteoporosis Screening Guidelines in IBD: Bone Loss Incidence, Risk Factors and Influence on Patient Management Asher Kornbluth, Sari Feldman, Carol Bodian, Michele Kissous-Hunt, James George, Simon Lichtiger, Peter Legnani The Induction of Antinuclear Antibodies Following Infliximab Treatment Is Not Related to Profound CRP Down Regulation Severine Vermeire, Maja Noman, Gert Van Assche, Tibor Hlavaty, Paul Rutgeerts Thiopurine Drug Metabolite Levels Guide Treatment in Ulcerative Colitis Ernest G. Seidman, Yves Theoret, Rachel Fisher, Jessica Seidman, Devendra Amre Activation of NF-KB Pathway (NF-KB Inducing Kinase / NIK, I-KB kinase B/g-K, I-KBa, NF-KB subunits) And Cytoskeletal Protein Instability in The Mucosa of Patients With Inflammatory Bowel Disease (IBD) Ali Banan, Maliha Shaikh, Ece Mutlu, Lijuan Zhang, Sri Kommanduri, Ashkan Farhadi, Ati Keshavarzian A Multi-tissue Analysis of Crohn's Disease (CD) and Ulcerative Colitis (UC) Etiopathology Using Microarrays Thierry Dervieux, Yuhong Tang, Craig Cadwell, Vera Lew, Igor Dozmorov, Miner Philippe, Chris Sutton, Russell Richerson, Michael Centola Calcaneal Ultrasound Bone Densitometry Is Not a Useful Tool to Screen Patients With Inflammatory Bowel Disease (IBD) at High Risk for Metabolic Bone Disease David A. Schwartz, Chris Connolley, Tatsuki Koyama, Amy Artrip, Jackie Beekley, Alan Herline Change in Red Cell MCV from 0-3 months (AMCV) and Its Relationship to 6 Thioguanine (6TG) Levels and Clinical Response in Inflammatory Bowel Disease (IBD) Patients Taking Thiopurine Drugs John L. H. Wong, Tamara Galloway, Harvey Dymond, Belinda Headon, John Lowes, Dermot McGovern, Harry Dalton Backwash Ileitis Is Under Reported in IlealPouch-Anal Anastomosis Patients Ayman S. Abdelrazeq, Derek L. Leitch, Jonathan N. Lund, Stephen H. Leveson Association of Antibodies to Exocrine Pancreas with Subtypes of Crohn's Disease Frank Klebl, Frauke Bataille, Christian Huy, Ferdinand Hofstaedter, Juergen Schoelmerich, Gerhard Rogler Malabsorption Is the Main Contributor to Underweight in Crohn's Disease Patients in Remission Nachum Vaisman, Iris Dotan, Eva Niv, Ofra Kaidar, Zamir Halperin $1387 Effects of Natalizumab on Gut Healing in a Phase 3 Study of Active Crohn's Disease Therapy (ENACT-l) Paul Rutgeerts, Miles C. Allison, Antoine Cortot, Geert D'Haens, Jens F. Dahlerup, Xavier Hebuterne, Karsten Lauritsen, Robert Lotberg, Thomas Ochsenkuhn, Stefan Schreiber, Denis Vetter, Karel Geboes $1400 C677T and A1298C Methylenetetrahydrofolate Reductase(MTHFR) Gene Polymorphism Does Not Predict Toxicity or Efficacy of Methotrexate in Patients with Inflammatory Bowel Disease Su Yang Soon, Azhar R. Ansari, Tony Marinaki, Monica Arenas, Konstantina Magdalinou, Jeremy Sanderson S1388 The Clinical Implication of Glucocorticoid Receptor[3 Expression and NFKB in Patients with Ulcerative Colitis Yun-Jung Lee, Seung Jae Myung, Suk-Kyun Yang, Jeong Sik Byeon, Jin Yong Jeong, Sun Mi Lee, Gin Hyug Lee, Do Ha Kim, Weon-Seon Hong, Jin Ho Kim, Young Min $1401 A Prospective Comparative Study of ASCA and ANCA in Chinese and Caucasian IBD Patients fan C. Lawrance, Rupert Leong, Kevin Murray, Anne Hall, Joseph J. Y. Sung P-132 ~ Denotes DDW Poster of Distinction

22 POSTER SESSIONS~CLINICAL SCIENCE ~: ~ ; $ Medical Treatment Recovered Redox Imbalance in the Colonic Mucosa of Ulcerative Colitis Yoshihiro Erignchi, Seiji Tsunada, Ryuichi Iwakiri, Tak Y. Aw, Kazurna Fujimoto Pharmacodynamic Results from a Phase 3 Study Evaluating Natalizumab Therapy of Active Crohn's Disease (ENACT-l) Ian Lawrance, Jean-Frederic Colombel, Robert Enns, Brian Feagan, Stephen B. Hanauer, Remo Panaccione, William J. Sandborn, Martin Sanders, Stefan Schreiber, Stephan R. Targan, Sander J. van Deventer, Paul Rutgeerts Azahioprine Efficacy in Corticodependent Patients with Inflammatory Bowel Diseases Xavier Roblin, Francoise Serre-Debeauvais, Frederic Heluwaert, Jean-Marc Phelip, Germain Bessard, Jean-Luc Faucheron, Bruno Bonaz Ileal Thickening: Radiographic Features Predictive of Crohn's Disease on Abdominal CT Scan Christopher Gasink, Stephen Rulyak, Stephen Rubesin, Rena Desai, James Lewis, Bernard Birnbaum, Jill E. Jacobs, Matthew Gardiner, Gary R. Lichtenstein ASCA Positivity is Associated with Increased Risk for Early Surgery in Patients with lleocolonic Crohn's Disease David G. Forcione, Michael J. Rosen, John B. Kisiel, Bruce E. Sands S1414 $1415 S1416 $1417 S1418 Health-related Quality of Life (QOL) in Patients with Crohn's Disease (CD) of Pouch, Active Pouchitis and Cuffitis After Ileal Pouch-anal Anastomosis (IPAA) Bo Shen, Bret Lashner, Reza Remzi, Aaron Brzezinski, Jhony Doumit, Ana Bennett, Jane Bast, Marlene Bambrick, Victor Fazio Natalizumab Decreases Inflammatory Cells Within the Colonic Lamina Propria of Patients with Active Crohn's Disease: Results from ENACT-1 Karel Geboes, Miles C. Allison, Antoine Cortot, Geert D'Haens, Jens F. Dahlerup, Xavier Hebuterne, Karsten Lauritsen, Robert Lot-berg, Thomas Ochsenkuhn, Stefan Schreiber, Denis Vetter, Paul Rutgeerts A 6-TGN Level Superior to 250 pmoles/8xl08 RBC Under Azathioprine ls of Clinical Interest in Patients with Crohns Disease or Ulcerative Colitis Xavier Roblin, Francoise Serre-Debeauvais, Frederic Heluwaert, Jean-Marc Phelip, Germain Bessard, Jean-Luc Faucheron, Bruno Bonaz Mesenteric Blood Flow Reflects Mucosal Blood Flow in Patients with Inflammatory Bowel Disease Roll D. Klingenberg-Noftz, Ntis Homann, Diether Ludwig Expression of Glucocorticoid Receptors mrna in Patients with Crohn's Disease (CD) Ruth Towers, Timna Naftali, Gila Gabay, Mathias Carlibach, Ami Klein, Ben Novis $1407 S1408 S1409 ; : Serologic Markers (ANCA/ASCA) are Associated with the Development of Postoperative Fistulae in Subjects with Inflammatory Bowel Disease Undergoing Ileal Pouch-Anal Anastomosis Kleanthis G. Dendrinos, James M. Becker, Arthur F. Stucchi, Lawrence J. Saubermann, Wayne W. Lamorte, Francis A. Farraye Thiopurine Methyhransferase and the Metabolism of Thiopurine Drugs in a Large Swedish Population Ulf Hindorf, Sven Almer, Curt Peterson Technetium-99m Labelled Leukocyte Single Photon Emission Computerised Tomography (SPECT) for Crohn's Disease Assessment Livia Biancone, Francesca Capoccetti, Alessandra Geremia, Carmen Petruzziello, Daniele Fina, Rosamaria Bozzi, Giovanni Simonetti, Orazio Schillaci, Francesco Pallone Glucocorticoid Receptor oz and [8 Messenger RNA Expression Is Not Correlated with Treatment Efficacy of Glucocorticoids in IBD Patients Martin Hausmann, Tanja Spoettl, Thomas Langmann, Sabine Fink, Werner Falk, Juergen Schoelmerich, Hans Herfarth, Gerhard Rogler Faecal Myeloperoxidase vs Calprottectin: As a Noninvasive Marker of Intestinal Inflammation in Inflammatory Bowel Disease (IBD) Omiea Azooz, Anne Ballinger Intestinal Granulomas Are Associated with Stricturing Phenotype and Colonic Involvement in Chinese Patients with Crohn's Disease Rupert W. L. Leon& Ka F. To, James Y. W. Lau, Joseph J. Y. Sung S1419 S1420 S1421 S1422 S1423 $1424 A Comparison Among Four Neutrophil-derivcd Prolein~ in Feces as Indicator of Disease Activity in Ulcerative Colitis Jost Langborst, Twyla Mueller, Jame> Boone, ~irrid Elsenbrucb, Guenthcr Spahn, Andrea> Mk hal,on. Gust:/\ Dobos Maintenance Infliximab Treatment ls Associated with Improved Bone Mineral Density in Crohn's Disease M. Bernstdn, S. hwin, H. Steinhart, G R Grccnhc~g Measurement of 6-thioguanosine Mono-, Di- and Triphosphates for Monitoring of Azathioprinc rhcrap?, in IBD Markus F. Neurath, Ralf Kiesslidl, Claudia Fi>chcr L/c Teichgraeber, Uhike Hotmann, Peter R Gal/c, Mallhia, Schwab Cytokine Stimulated CXC Chemokine Responses by Peripheral Blood Mononuclear Cells Reflect Levels of Disease Activity in Crohn's Disease Francis A. Farraye, Kenny S. Yung, Victor M. Morales, Katherine L. Schaefer, Lawrence J. Saubermann Serial Fecal Lactoferrin Measurements Are Useful in the Interval Assessment of Patients with Active and Inactive Inflammatory Bowel Disease Thomas R. Walker, Michelle L. Land, Tracee M Cook, James H. Boone, David Lyerly, Paul A. Rufo Pharmacogenetic Profiling in Azathioprine Therapy: The Role of TPMT, ITPA And MTHFR Polymorphisms in Drug Toxicity Azhar R. Ansari, Suyang Soon, Shariqa Raoof, Monica Arenas, Cathryn Lewis, John Duley, Tony Marinaki, Jeremy Sanderson Interobserver Agreement Analysis of the Vienna Classification Anna Oefferlbauer-Ernst, Wolfgang Miehsler, Otto Eckmuellner, Alfred Gangl, Harald Vogelsang, Walter Reinisch $1425 Perinuclear Antineutrophil Cytoplasmic Antibody(p- ANCA) and Anti Saccharomyces Cerevisiae antibody(asca)incidence May Vary Among Different Ethnic Groups with Inflammatory Bowel Disease(IBD) Dhiman Basu, Harsha Allu, Joseph H. Sellin Denotes DDW Poster of Distinction P-133

23 S U N D A Y MAY 16 S1426 $1427 S1428 $1429 Is Deposition of Split Complement Fraction C4d a Marker of Antibody-Mediated Gut Damage in Inflammatory Bowel Disease? Iarl D. R. Arnott, Carolyn Li, Peter Shintaku, Ian McGowan, Peter Anton, Jonathan Braun Presence of Antibodies to Saccharomyces Cerevisiae (ASCA) Correlates with Risk of Ileocecal Resection in Children and Young Adults with Crohn's Disease Anna Zholudev, David Zurakowski, Wes Young, Athos Bousvaros, Alan Leichtner Small Bowel Crnhn's Disease: Enterodysis, Bowel Sonography and Tc-99m-HMPAO Leukocyte Scintigraphy at Comparison Fabiana Castiglione, Antonio Rispo, Massimo Imbriaco, Luigi Celentano, Antonio Cozzolino, Luigi Camera, Pier Paolo Mainenti, Francesco Manguso, Elena Di Girolamo, Gabriele Mazzacca Early and Transient Increase of 6-TGN After Infliximab Infusion in Patients with Crohns Disease Under Azathioprine: Possible Mechanisms Xavier Roblin, Francoise Serre-Debeauvais, Frederic Heluwaert, Jean-Marc Phelip, Germain Bessard, Jean-Luc Faucheron, Bruno Bonaz AM-5:00 PM Hall F (~ Sponsored by: Motility & Nerve-Gut Interaction SMALL BOWEL AND COLONIC MOTILITY GDNF (Glial Cell-Derived Neurotrophic Factor) Release $1430 During the Peristaltic Reflex Induces a Selective Increase in Motor Neurotransmitter Release and Enhances the Peristaltic Reflex John R. Grider Colonic 5-HT and Muscle Responses to the Same $1431 Infectious Agent Differ in Thl and Th2 Dominant Environments Yasuaki Motomura, Monica Verma-Gandhu, Rami T. E1- Sharkawy, John McLaughlin, Richard K. Grencis, Waliul I. Khan Classical Conditioned Response of Rectosigmoid S1432 Motility and Regional Cerebral Activity in Human Motoyori Kanazawa, Masatoshi Endo, Keiichiro Yamaguchi, Toyohiro Hamaguchi, William E. Whitehead, Masatoshi Itoh, Shin Fukudo Neural Gastrointestinal Electrical Stimulation (NGES) S1433 Enhances Colonic Motility in a Canine Model of Constipation Claudia P. Sanmiguel, Sergio Casillas-Romero, Laurence Turner, Anthony Senagore, Martin P. Mintchev, Edy E. Softer Comparative Distribution of NK1, NK2 and NIO S1434 Tachykinin Receptors in the Ganglionated Plexus and External Muscle Layers of the Human Colon Nadia Jaafari, Martine Liberge, Marie-Odile Christen, Yvon Jule Serotonin Transporter Gene Polymorphism and Its S1435 Relationship of Plasma Serotonin in Irritable Bowel Syndrome Hyojin Park, Sang Won Ji, Dock Yong Lee, Sang In Lee POSTER SESSIONS--CLINICAL SCIENCE S1436 $1437 S1438 $1439 S1440 $1441 S1442 S1443 S1444 S1445 S1446 S1447 S1448 Influence of Tegaserod on Sensorimotor Function of the Descending Colon in Man Maura Corsetti, Kwang-Jae Lee, Rita Vos, Jozef Janssens, Jan Tack Pathophysiology of Constipation and Biofeedback Therapy in Spinal Cord Diseases Ji H. Choi, Seung~Jae Myung, Suk-Kyun Yang, Jeong-Sik Byeon, In J. Yoon, Oh R. Kwon, Jung Eun Ko, Yun-Jung Lee, Gin Hyug Lee, Weon-Seon Hong, Jin-Ho Kim, Young 11 Min Colocalization and Direct Binding of Tropomyosin to Protein Kinase Codn Colonic Smooth Muscle During Agonist-Induced Contraction Sita Somara, Mercy D. Pawar, Haiyan Pang, Louise Hecker, Khalil N. Bitar Influence of Sildenafil on Colonic Sensorimotor Function in Man Maura Corsetti, Rita Vos, Jozef Janssens, Jan Tack Increased Expression of Substance P, Neuropeptide K and Galanin in Mucosal Nerves of Patients with Painful Diverticular Disease John Simpson, Frank Sundler, David Jenkins, John H. Scholefield, Robin C. Spiller Indication of Measurement of Colonic Transit Time in Patients with Functional Constipation Belch Herreros, Miguel Minguez, Vicente Sanchiz, Vicent Hernandez, Cirilo Amoros, Amaya Basagoiti, Francisco Mora, Adolfo Behaves Polyethylene Glycol 3350 for the Treatment of Constipation in Children under the Age of 2 years Dinesh S. Pashankar, Vera Loening-Baucke, Rachana Krishna, Jacquelyn Comstock Bulking Agents for the Treatment of Irritable Bowel Syndrome; a Meta-analysis A. Otto Quartero, Nick de Wit, Villy Meiniche-Schmidt, Jean Muris, Greg Rubin The Possible Role of Kynurenic Pathway Metabolites in the Mechanism of Visceral Pain in Patients with Irritable Bowel Syndrome Grazyna Rydzewska, Tomasz Wollny, Dariusz Pawlak, Ewa Turecka-Kulesza, Wlodzimierz Buczko Elevated Apoptotic Cell Death in Enteric Neurons and Intramuscular Interstitial Cells of Cajal from Colon of Patients with Slow-Transit Constipation Simon J. Gibbons, Roberto De Giorgio, Steven M. Miller, Phili p F. Schmalz, Tonia M. Young-Fadok, Joseph H. Szurszewski, Vincenzo Stanghellini, Gianrico Farrugia The Effect of Naloxone-3-glucuronide (NXG) and N- Methylnaloxone (MNX) on the Motility of the Isolated, Perfused Rat Colon After Morphine Stimulation Peter Reber, Rudolf Brenneisen, Beatrice Flogerzi, Patrick = Reber, Catarina Batista, Ulrich Scheurer Role of Cannabinoid CB1 and Tachykinin NK1 Receptors in Electrically Evoked Responses of Longitudinal Smooth Muscle Strips From Human Colonic Diverticulosis Fabio Guagnini, Tiziano Croci, Silvano Mukenge, Gianfranco Ferla, Anne-Marie Galzin, Gerard Le Fur Characterization of Abnormal Colonic Motor Activity in Children After Surgery for Hirschsprung's Disease: Results of a Multicenter Study Ajay Kaul, Frances Connor, Jose Cocjin, Keith McConnell, Alejandro Flores, Paul Hyman, Carlo Di Lorenzo I P-134 ~ Denotes DDW Poster of Distinction

24 POSTER SESSIONS--CLINICAL SCIENCE S1450 S1451 SI452 Abnormalities of Mucosal 5-Hydroxytryptamine (SHT) Metabolism in Post-Infective and Constipated IBS Simon P. Dunlop, Gulzar Singh, Charles Marsden, Robin Spiller A Scoring Method on Plain Abdominal X-Rays in the Diagnosis of Childhood Constipation Revisited Fleur de Lorijn, Jarom Heijmans, Rick van Rijn, Jan Taminiau, Marc Benninga lndiscriminant Loss of Neurons in the Myenteric Plexus of the TNBS-Inflamed Guinea Pig Distal Colon David R. Linden, Jennifer M. Couvrette, Keith A. Sharkey, Gary M. Mawe Tolerance of Long Term Administration of PEG 4000 In Elderly Patients Suffering from Chronic Constipation Philippe Chassagne Sr., Gerard Feuvrier, Bertrand Souliac, Roger Eoche, Philippe Gamier, Helene Mathiex-Fortunet, Eric Bercoff $1464 S1465 $1466 $1467 Video Mapping and Extracellular Recording Studies of Nutrient-Induced Segmentation in Isolated Guinea-Pig Small Intestine Rachel M. Gwynne, Kathleen B. Neal, Linette L. L. Tan, Anna Dombeck, Ed C. Chang, Joel C. Bomstein Identification and Preferential Expansion of Potential Interstitial Cells of Cajal in Cell Culture of Human Intestinal Smooth Muscle Cells Daisuke Kobayashi, Akiko Terauchi, Hiroshi Mashimo Intestinal Manipulation Causes Postoperative Ileus via an Inhibitory Sympathetic Efferent Pathway Hiroyuki Fukuda, Daisuke Tsuchida, Christopher R. Mantyh, Theodore N. Pappas, Toku Takahashi Expression of NKCC 1, a Na +-K +-2Cl- Cotransporter, by Myenteric Interstitial Ceils of Cajal in the Jejunum Mira Wouters Jr., Karine Smans, Alban de Kerchove d'exaerde, Jean Marie Vanderwinden S1453 $1454 i $1455 $1456 $1457 $1458 St459 $1460 S1461 Continuous Rectal Distension Has a More Pronounced Slowing Effect on Gastric Emptying in Females with Slow Transit Constipation Than in Healthy Women Georges Coremans, Rita Vos, Vassilios Margaritis, Yvo Ghoos, Jozef Janssens Table to Toilet (T.T.T.) Program for Management of Chronic Constipation and Encopresis Manoochehr Karjoo, Shannon Kesselring Substance P-Induced Expression and Endocytosis of NK1 Tachykinin Receptor on Muscle Cells of the Human Colon Hikma Boutaghou-Cherid, Martine Liberge, Marie-Odile Christen, Yvon Jule The Effects of a 2-Week Period of Daily Administration of Sildenafil on Stool Frequency, Stool Consistency and Colon Transit in Healthy Men Mark Milone, John DiBaise Impaired Electrical and Mechanical Patterns and Distribution of Interstitial Cells of Cajal in the Colon of Ws/Ws Rats Elena Alberti, Hanne B. Mikkelsen, Jytte O. Larsen, Marcel Jimenez Diurnal Pattern and Reproducibility of Colonic Motility During Ambulatory Recording Eduard van Hoboken, Melek Yuksel, Ad Masclee Clinical and Functional Effects of Antidepressant/ Anxiolytic Therapy in Patients with Functional Constipation Belen Herreros, Miguel Minguez, Vicente Sanchiz, Vicent Hernandez, Cirilo Amoros St., Amaya Basagoiti, Francisco Mora, Adolfo Benages Immunological Activation in Patients with Irritable Bowel Syndrome Lena Ohman, Magnus Simren, Henrik Sjovall Neuromodulation of Colonic Motility by Cyclooxygenase Isoforms in the Presence of Experimental Bowel Inflammation Matteo Fomai, Luca Antonioli, Rocchina Colucci, Cristina Segnani, Nunzia Bemardini, Corrado Blandizzi, Amelio Dolfi, Mario Del Tacca S1468 $1469 S1470 S1471 $1472 $1473 S1474 S1475 S1476 Effects of Clonidine on Stool Parameters and Gastrointestinal Transit in Diabetics with Chronic Diarrhea and Autonomic Neuropathy: A Double-Blind, Placebo-Controlled Trial Lucilene Rosa-e-Silva, Luiz E. A. Troncon, Ricardo B. de Oliveira, Lourenco Gallo Jr., Milton C. Foss Increased Ileal Response to Neurotransmitters in Leptin- Deficient Obese Mice Following Small Bowel Resection James M. Kiely, Jae H. Nob, Keun H Lee, Shannon 1 Graewin, Hen U A. Pitt, Deborah A. Swartz-Bastle Peripheral Slow Wave Pacemakers and Retrograde Propagation Revealed with High-Resolution Electrical Mapping in the Canine Small Intestine in vivo Wim J. E P. kammers, Luc Vet Donck. Jan A. J Schuurkes, Betty S. Stephen Deranged Smooth Muscle Alpha-actin: A Bio-marker of Intestinal Pseudo-obstruction. A Controlled Multinational Case Series Charles H. Knowles, David B. A. Silk. Ara Darzi, Roger Feakins, Ana Raimundo, Bela \:cress, Tom Crompt~,~. Greger Lindberg, Joanne E. Martin Impedance Improves the Analysis of Duodenal Peristaltic Patterns in Healthy Subjects Huan Ngyuen, Gerson Domingues, Ron Winograd, Frank Lammert, Jiri Silny, Siegfried Matern Intestinal Electrical Stimulation Inhibits Antral Motility via Sympathetic Pathway but Not Nitric Oxide Pathway in Conscious Dogs Xiaotuan Zhao, Lijie Wang, J. D. Z. Chen Inhibitory Effects of Single Channel Intestinal Electrical Stimulation on Motility of the Entire Small Intestine in Dogs Shi Liu, Lijie Wang, Douglas L. Brining, J. D. Z. Chen Duodenal Acid Clearance : What Can We Learn from Intraluminal Impedance Recordings? Guillaume Savoye, Jac Oors, Andre Smout The Wavelength of the Slow Wave Shortens Distally Ten-fold Along the length of the Canine Small Intestine Wim J. E. P. Lammers, Luc Ver Donck, Jan A. J. Schuurkes, Betty Stephen S1462 Influence of Motilin on Colonic Sensitivity to Distension and Motor Response to an Orally Ingested Meal in Man Maura Corsetti, Rita Vos, Theo Peeters, Josef Janssens, Jan Tack $1477 High Prevalence of Putative Slow EPSP Dysfunction in Irritable Bowel Syndrome (IBS) Magnus Simren, Evan A. Thomas, Joel C. Bomstein, Henrik Sjovall $1463 NK2 Receptors Mediate Spontaneous Contractions of Human Sigmoid Circular Smooth Muscle Weibiao Cao, Fabio M. Potenti, Victor E. Pricolo $1478 The Direction of the Pendular Swing Is Determined by the Direction of the Slow Wave Propagation Wim J. E. P. Lammers, Sekar Dhanasekaran, Betty Stephen, John R. Slack Denotes DDW Poster of Distinction P-135

25 POSTER SESSIONSnCLINICAL SCIENCE S1479 S1480 S1481 S1482 $1483 Novel Soft Ionization Mass Spectrometry (SIMS) Monitors Several Components in Human Breath: Studies in the Fasting and Fed Period in Healthy Subjects Piero Portincasa, Sigfried Praun, Massimo Berardino, Antonio Moschetta, Giuseppe Pistoia, Roberta Montelli, G. Scaccianoce, J. Vfllinger, Giuseppe Palasciano Oro-eecal Transit Time: The Influence of a Subsequent Meal Marion G. Priebe, Renate E. Wachters-Hagedoom, Frans Stellaard, Marius A. Heiner, Henk Elzinga, Roel J. Vonk The Degree of Methane on Lactulose Breath Test Correlates with the Severity of Constipation in IBS Subjects Mark Pimentel, Yuthana Kong, Sandy Park, Evelyn Chow Nitric Oxide Is Not Involved with the Inhibitory Effect of Electrical Stimulation on Intestinal Motility in Dogs Shi Liu, Jinsong Liu, Lijie Wang, Douglas L. Brining, J. D. Z. Chen Study of the Association Between Small Intestinal Bacterial Overgrowth and Patients with Irritable Bowel Syndrome Brennan Waiters, Stephen Vanner $1491 $1492 S1493 S1494 S1495 Rising Incidence of Hospitalization for Acute Pancreatitis in the United States from 1985 to 2000 Albert B. Lowenfels, John Fiorianti, Thomas Sullivan Significant Elevation of Serum IL-18 Levels in Patients with Acute Pancreatitis Takashi Ueda, Yoshifumi Takeyama, Naoki Matsumura, Hidehiro Sawa, Makoto Shinzeki, Yoshikazu Kuroda The Role of PMN Elastase and CRP on the Diagnosis and Assessment of Severity of Acute Pancreatitis Margarita Kitsanou, Konstantinos H. Katsanos, Dimitrios Christodoulou, George Kalabokis, Afroditi Katsaraki, Niki Kontodimou, Epameinondas V. Tsianos Peripancreatic Fluid Collections in Severe Acute Pancreatitis (SAP): Correlation Between Computerized Tomography Scan and Surgery Santhi Swaroop Vege, Joel G. Fletcher, Michael G. Sarr, Peter B. Wold, Jared A. Christensen, Suresh T. Chari Microalbnminuria as Risk Factor for Organ Failure and Death in Acute Pancreatitis. A Prospective Trial Dora A. Garcia-Cantu, Jose A. Gonzalez-Gonzalez, Nancy Rodriguez-Dominguez, Daniel O. Rodriguez-Perez, Hector J.J. Maldonado-Garza i ~ ~i~ i~i i IS U N ~ A Y MAY 16 i i S1484 Evidence That Altered Motility Contributes to Host Defense in Nematode Infection Waliul I. Khan, Yasuaki Motomura, Elena F. Verdu, Patricia A. Blennerhassett, Rami T. E1-Sharkawy, Monica Verma- Gandhu, Stephen M. Collins AM-5:00 PM Sponsored by: Pancreatic Disorders ACUTE AND CHRONIC PANCREATITIS Hall F Using Machine Learning to Predict Severity in Acute Pancreatitis g Callum B. Pearce, Steve R. Gunn, Adil Ahmed, Colin D Johnson Mild Acute Pancreatitis: A Frequent Inaccurate S1486 Diagnosis in Severe Hyperemesis Syndrome of Pregnancy Michael A. Pappas, Kabeya Mwintshi, Charlene M. Prather, Michael Firth, Raul Artal, Frank R. Burton Serum Levels of Carboxypeptidase A and Pro- S1487 Carboxypeptidase A as Predictors of Severe Pancreatitis Dengda Tang, Mark J. Sterling, Tsu-Hong Wang, Ameet Parikh, Kenneth Belitsis, Charles Gilvarg A Simple Score Plus Serum C- Reactive Protein at S1488 Admission Increase the Positive Predictive Value for g Organ Failure in Severe Acute Pancreatitis. A Prospective Trial Dora A. Garcia-Camu, Jose A. Gonzalez-Gonzalez, Nancy Rodriguez Dominguez, Daniel 0. Rodriguez Perez, Hector J.J Maldonado-Garza Oxidative Stress (OS) in Acute Pancretatitis (AP) S1489 According to Severity Vicent Hemandez, Maria Miranda, Pedro A/mela II1, Ramon Anon, Belen Herreros, Cirilo Amoros Sr., Isabel Pascual, Vicente Sanchiz, Francisco J. Romero, Adolfo Benages Long-Term Follow-up of Acute Recurrent Pancreatitis S1490 Luca Frulloni, Barbara Fern, Anna Katsotourchi, Laura Bernardoni, Elena Coato, Katia Faitini, Silvia Biasin, Franca Patrizi, Bruna Vaona, Giorgio Cavallini S1496 S1497 S1498 S1499 S1500 $1501 S S 1503 g Multivariate Analysis of Stone-related and Anatomical Factors Predisposing to Acute Biliary Panereatitis Masanori Sugiyama, Yutaka Suzuki, Nobutsugu Abe, Osamu Yan~gida, Tadahiko Masaki, Toshiyuki Mori, Yutaka Atomi Antibiotic Prophylaxis in Large Pancreatic Necrosis: Muhicenter Randomized Trial with Ciprofloxacin and Metronidazol or Meropenem Julius Spicak, Sona Hejtmankova, Petr Cech, David Hoskovec, Rodomil Kostka, Jan Leffler, Mojmir Kasalicky, Petr Svoboda, Jolana Bartova Comparison of Outcomes of Patients with Severe Acute Pancreatitis (SAP) Admitted Directly to a Tertiary Care Center with Outcomes of Patients Transferred from Outside Facilities Santhi Swaroop Vege, Suresh T. Chari, Luis F. Lara Pincay, Jonathan E. Clain, Randall K Pearson, Vicky L. Courson, Joanna R. Jones, Padma N. Munukuti, Michael B. Famell, Michael G. Sarr Urinary Trypsinogen - A Predictor of Post-ERCP Acute Panereatitis Ranvir Singh, Tahir Mugal, Maher Madhoun, Pankaj Singh, Nakechand Pooran, Bernard Stark, Simmy Bank Percutaneous External Drainage of Infected Collections in Severe Acute Pancreatitis Bartoli Eric, Houmani Zaher, Delcenserie Richard, Yzet Thierry, Brazier Franck, Geslin Guillaume, Lagarde Marine, Dupas Jean Louis Prevalence of Pancreatitis and Association with Nonalcoholic Fatty Liver Disease in Ninety Patients with Severe Hypertriglyceridemia Alan Chiemprabha, Roger Smith, John R. Crouse, Jamal A. Ibdah Treatment of Pancreatic Stones with Extracorporeal Shock Wave Lithotripsy: Results of a Muhicenter Survey Kazuo Inui, Susumu Tazuma, Taketo Yamaguchi, Hirotaka Ohara, Tadao Tsuji, Hiroyuki Miyakawa, Yoshinori Igarashi, Yutaka Atomi, Yuta Nakamura Prevalence and Causes of Malnutrition in Patients with Chronic Panereatitis Yogendra K. Joshi, Namrata Singh, Pramod K. Garg, Rakesh K. Tandon P-136 g Denotes DDW Poster of Distinction

26 POSTER SESSIONS~CLINICAL SCIENCE S ~ St506 $1507 ~00 S1508 $1509 S1510 S1511 Availability of Oral Litholysis Therapy and Its Combination with ESWL and Endoscopic Treatment in Chronic Pancreatitis Aiji Noda Low Fecal Elastase-1 Values Do Not Reliably Indicate Exocrine Pancreatic Insufficiency in Type 1 Diabetes Mellitus Paul G. Lankisch, Jan-Uwe Hahn, Sabine Bochnig, Helma Koenig, Birgit Sporleder, Patrick Maisonneuve, Albert B. Lowenfels, Wolfgang Kerner A Simple Test for the Exocrine Function of the Pancreas Using 13C-Dipeptide Exhalation Yukimoto Ishii, Shigeru Suzuki, Tomohisa Kohno, Tadashi Kohno, Kimitoshi Katoh, Yasuyuki Arakawa, Tadatoshi Takayama, Satoshi Asai Probability of Exocrine Pancreatic Insufficiency (EPI) in Patients with Severe Chronic Pancreatitis (CP) According to the Findings on Endoscopic Uhrasonography (EUS) Julio Iglesias-Garcia, Maria Vilarino-Insua, Marta Iglesias- Rey, Miguel Sobrino-Faya, Enrique Dominguez-Munoz Direct Measurement of Pancreatic Elastase 1 (PE-1) in Duodenal Aspirates from Healthy Subjects (HS)and Patients with Chronic Pancreatitis (CP) Tyler Stevens, Darwin L. Conwell, Frederick Van Lente, John J. Vargo, Gregory Zuccaro, Patrick Hanaway Long Term Clinical Outcome After Endoscopic Pancreatic Ductal Drainage for Patients with Painful Chronic Pancreatitis Myriam Delhaye, Marianna Arvanitakis, Gontran Verset, Michel Cremer, Jacques Deviere How to Treat Severe Exocrine Pancreatic Insufficiency? A Prospective Randomized Study Comparing High Doses of Pancreatic Enzymes Versus Standard Doses plus Esomeprazole Pierre H. Deprez, Jean-Francois Gigot, Jean-Paul Da Silva Pinto, Andre Geubel, Yves Horsmans Prevalence of Autoantibodies against Pancreatic Secretory Trypsin Inhibitor (PSTI) as a Novel Diagnostic Marker for Patients with Autoimmune Pancreatitis Masanori Asada, Akiyoshi Nishio, Kazushige Uchida, Hiroshi Kitamura, Satoko Inoue, Keiichi Kiriya, Shinya Ohashi, Hazuki Yoshizawa, Hiroyuki Tamaki, Toshiro Fukui, Kimio Kawasaki, Minoru Matsuura, Hiroshi Nakase, Kazuichi Okazaki, Tsutomu Chiba ASGE Poster Session Authors are required to be present during the Poster Session from 12:00-2:00 pm. AM-5:00 PM Hall F MISCELLANEOUS PREPARATION, SEDATION, GENERAL ENDOSCOPY Frequency of Complications After Endoscopic S1512 Ultrasound-Guided Fine Needle Aspiration of Solid Pancreatic Masses: A Prospective Evaluation Mohamad A. Eloubeidi, Shyam Varadarajulu, Charles M. Wilcox $1513 S1514 $1515 $1516 S1517 S1518 $1519 S1520 Risk Factors for Post-Polypectomy Hemorrhage of Colon: A Preliminary Result of a Multi-Center Study Kim Hyun-Soo, Young-Ho Kim, Won Ho Kim, Tae I1 Kim, Hyo Jong Kim, Seung Jae Mynng, Suk-Kynn Yang, Ki Myung Lee, Moon Sung Lee, Moon Kwan Chung, Sung-Ae Jung, I1 Kwon Chung, Yoon Tae Jeen, Jai Hynn Choi, Hwang Choi, Dong-Soo Han, Jae Suk Song Risk Factors for Post-EMR Hemorrhage in Patients with Gastric Tumor Kim Hyun-Soo, Suk Ki Tae, Kim Jeong Min, Chung Pil Ho, Balk Soon Koo, Lee Dong Ki, Kwon Sang Ok Hemorrhagic Complication of Endoscopic Polypectomy Is Liable to Occur in Patient with Hypertension Hirotsugu Watabe, Shintaro Kondo, Miki Ota, Tsuneo Ikenoue, Goichi Togo, Yutaka Yamaji, Makoto Okamoto, Takao Kawabe, Masao Omata Pre-, Intra-, and Post-Procedure Risk Factors for Post- ERCP Pancreatitis Bret T. Petersen, Robert Yacavone, Nicole Pochron, W. Scott Harmsen, Alan Zinsmeister, Todd Baron, Christopher Gostout, Maurits Wiersema Risk Factors Related to Bleeding in Gastric Tumors after Endoscopic Mucosal Resection Chang Min Cho, Dong Seok Lee, Chang Keun Park, Won Young Tak, Young-Oh Kweon, Sung Kook Kim, Yong Hwan Choi Factors Associated with Bleeding After Endoscopic Mucosal Resection of Gastric Tumors Yun Jung Challg, Jong-Jae Park, Ki Ho Park. G)eI>,, t~h Kim, Hyung Joon Yim, jin 'fnng Khn long Vtm Ycon. J~< Seon Kim, K~\an Soo Byun. Yotuqg Tac Bak. Chan C H<qu' Lee Chronic Atrial Fibrillation: Considerably Increased Risk for Patients Undergoing the Endoscopy of The Upper Gastrointestinal Tract Lubomir Michalko, Ludovit Gabpar, Stela HIh>la/<t,\.t Safety of Band Ligator Use in the Small Bowel and Colon Kevin B. Barker ASGE Poster Session AM-5:00 PM Hall F MISCELLANEOUS PREPARATION, SEDATION, GENERAL ENDOSCOPY $1521 $1522 $1523 $1524 Interventional Endoscopy at Ambulatory Endoscopy Centers (AEC): Is It Time? Daus Mahnke, Yang K. Chen, Mainor R. Amillon, William Brown, Roger Mattison, Raj J. Shah Introducing Manufacturing Efficiency Tools to the Endoscopy Suite: How the Toyota Model Helps Drive Endoscopes Drew Schembre, Patti Wilbur, Geoffery Jiranek, Carolyn Anderson, Joan Jarhus, Daphne Ducker, Linda Culp, Sharon Nash, Shanna Mosher, Susan Talbot, Donna Smith, Richard Kozarek Prospective Assessment of Endoscopic Ultrasound (EUS) Impact on Treatment Decision in an Unselected Cohort of 346 Patients Referred for Diagnostic EUS Enrique Vazquez-Sequeiros, Daniel Boixeda, Victor Moreira, Antonio Garcia Plaza A Prospective Survey on the Reasons Patients Fail to Complete Scheduled Endoscopic Procedures Gregory Olds, Thomas Brown, Gregory Cooper Denotes DDW Poster of Distinction P-137

27 POSTER SESSIONSmCLINICAL SCIENCE $1525 $1526 $1527 $1528 $1529 Endoscopic Disinfection: Comparison Between Electrolyzed Acid Water and 2% Glutaraldehyde Giancarlo Spinzi, Alessandro Rampoldi, Luca Ferlin, Riccardo Terramocci, Giancarlo Butti, Giorgio Minoli Creation of a Colonoscopy Screening Clinic for Improving Endoscopy Unit Efficiency Drew Schembre, Otto Lin, John Brandabur, David Patterson, Michael Gluck, Susan McCormick, Geoffery Jiranek, James Bredfeldt, Klaus Mergener, Richard Kozarek Mandatory Hygiene Control As a Key of Decreasing Failures of Endoscope Reprocessing in Ambulatory Care Berndt R. Birkner, H. K. Selbmann, S. Kleff, A. Munte Comparison of the Cancellation Rates of Open Access Versus Gastroenterologist Refered Endoscopies Gregory Olds, Thomas A. Brown, Gregory Cooper The Impact of Colonscopic Electrocautery on Pacemaker Function Navin Kumar, Hemant Roy, Alan Zunamon, Eva Gliwa, Mick Meiselman, Michael Goldberg, Tat-Kin Tsang, Randall Brand S1538 $1539 $1540 $1541 $1542 Evaluation of the CompactEASIE-Simulator for the Education in Endoscopic Hemostasis of Endoscopic Novices - A Prospective Randomized Trial Juergen Maiss, Lutz Millermann, Katja Heinemann, Norbert Krauss, Andreas Naegel, Andrea Peters, Eckhart G. Hahn, Juergen Hochberger The Impact of an ASGE Hands-on ERCP Workshop on Clinical Practice Robert E. Sedlack, Bret Petersen, Kenneth Binmoeller, Joseph Kolars Assessing Competency During ERCP Training: Objective and Subjective Perceptions by Trainees and Attendings Camron Kiafar, Rakesh Nanda, Francisco C. Ramirez Experience of Endoscopists and Radiation Exposure to Patients During ERCP Anthony Li, Danny Lee, Simon Wong, Angus Chan Uusedated Colonoscopy Performed by Trainees Under Supervision Felix W. Leung, S. Chu, B. Nguyen, S. Aharonian, R. Chitayat, M. Feinerman, P. Gulsrud, L. Jacobs s U N D A Y MAY 16 $1530 S1531 $1532 $1533 The Efficacy of a New Bees-Like Disposable Brush for the Scope Cleaning Masayuki Kato, Koji Matsuda, Chizuko Honda, Hisao Tajiri Usefulness of Attaching a Short Cap for Colonoscopy of Obese Patients Shintaro Kondo, Miki Ohta, Hirotsugu Watabe, Yutaka Yamaji, Makoto Okamoto, Takao Kawabe, Masao Omata The Value of Peracetic Acid (SCOTELIN ) for Endoscopic Disinfection Jin-Bae Kim, Dong-Soo Han, Jong-Pyo Kim, Hang-Lak Lee, Joo-Hyun Sohn, Yun-Ju Jo, Joon-Soo Hahm The Rate of Practice Changes in a Referral Endoscopy Unit Manuel Perez-Miranda, Maria L. Goyeneche, Flor Frias, Agustin Caro-Paton ASGE Poster Session AM-5:00 PM Hall F MISCELLANEOUS PREPARATION, SEDATION, GENERAL ENDOSCOPY $1543 S1544 $1545 S1546 S1547 Trainee and Trainer: A Prospective Study of Completion Times in Patients Attending for Routine Colonoscopy in a Single University Hospital Endoscopy Service Diarmuid S. Manning, Gayle Bennett, Suzi Clarke, Richard Walsh, Hugh E. Mulcahy Efficacy of a One Day Hands-on EASIE Endoscopy Simulator Train-The-Trainer Workshop Jonathan Cohen, Kai Matthes, Michael L. Kochman, Maurice A. Cerulli, Kinjal C. Vora, Juergen Maiss, Juergen Hochberger, New York Society for Gastrointestinal Endoscopy (NYSGE) Study Group Capsule Endoscopy Learning Curve Christopher P. Shaver, Joffre R. Rivera, Joseph McKinley, Patrick G. Brady Virtual Endoscopy Simulator: Can the Unexperienced Be Trained for Real Endoscopy? Ralf Kiesslich, Karsten Reinhardt, Ulrike Denzer, Stephan Kanzler, Stefan Moenk, Jochen Vollmer, Wolfgang Heinrichs, Markus F. Neurath, Peter R. Galle Training in Gastrointestinal Endoscopy in Canada: A Survey of Program Directors in Gastroenterology Frances Tse, David Armstrong, Alan N. Barkun $1534 $1535 S1536 $1537 A Six Month Follow-up on the Effectiveness of the Endoscopic Simulator in Training Colonoscopy Asyia Ahmad, Zaid Alnoah, Faullin Paletsky, Michael Kochman, Benjamin Krevsky, Steven Peikin, Giancarlo Mercogliano, Robert Boynton, James C. Reynolds, Philadelphia GI Training Group The Impact of Trainee Involvement on the Cecal Intubation Rate and Diagnostic Yield of Screening Colonoscopy Christopher S. Lee, Shahzad Iqbal, Samera Vaseer, Jennifer Northrop, Albert D. Min Quality of Performance at Screening Flexible Sigmoidoscopy Correlates with Adenoma Detection Rates Siwan Thomas-Gibson, David Swain, Gillian Schofield, Brian Saunders, Wendy Atkin Performance in Colonoscopy Can Be Reliably Scored in the First 8 Minutes of Insertion: Further Evidence for a Tri-split Video Assessment Tool Siwan Thomas-Gibson, Syed Shah, David Swain, Catherine Thapar, Gillian Schofield, Brian Saunders S1548 $1549 S1550 $1551 $1552 $1553 Is Pit Pattern Diagnosis Possible Even for Beginners? Nozomu Kobayashi, Takahisa Matsuda, Yutaka Saito, Daizo Saitoh Prediction of Endoscopic Skills on the Basis of General Unspecific Hand-Eye-Coordination Dexterity Test Juergen Maiss, Katja Heinemann, Lutz Millermann, Norbert Krauss, Andreas Naegel, Andrea Peters, Eckhart Hahn, Juergen Hochberger In the Absence of Feedback it is Not Possible to Improve Performance on the Colonoscopy Simulator Tariq Mahmood, Ara Darzi Training in Gastrointestinal Endoscopy in Canada: A Survey of Trainees in Gastroenterology Frances Tse, David Armstrong, Alan N. Barkun The Validation of Colonoscopy Simulator as a Teaching Tool Tariq Mahmood, Ara Darzi Comparison of Endoscopic Experience Obtained in an American and a British Gastroenterology Training Program Scan Weaver, Sanjib Mohanty, David Fine, Paul Winwood, Kim Isaacs, Ian Grimm P-138

28 r POSTER SESSIONS~CLINICAL SCIENCE :S1554 The Incidence of Bowel Perforations Is Positively Related to the Intensity of Pain Experienced During Simulated Colonoscopy Tariq Mahmood, Darzi Ara ASGE Poster Session AM-5:00 PM Hall F MISCELLANEOUS PREPARATION, SEDATION, GENERAL ENDOSCOPY Results of a Randomised, Multi-Centre, Single-Blind $1555 Trial to Compare the Efficacy, Acceptability and Safety of a New 2-Litre Gut Cleansing Solution Versus a Standard 4-Litre PEG + E Solution Christian Ell, Hans-Juergen Gruss Is Patient Acceptability of Oral Sodium Phosphate as S1556 Preparation for Colonoscopy as Good as Is Claimed? Amro Salem, David Underwood, William Dicky, Dafney Garrett, Paul Neilly, Robert Gilliland A Simplified Protocol for Endoscopist Administered S1557 Propofol For EUS Is Safe And Effective: A Prospective Study In 500 Patients lan Yusoff, Tju Slang Chua, Sarto Paquin, Genevieve Tessier, Ginette Raymond, Anand Sahai Testing and Development of a Device for Cleaning the S1558 Colon During Colonoscopy Annette Fritscher-Ravens, Sandy Mosse, Keiichi Ikeda, Paul Swain, S1559 $1560 $1561 $1562 $1563 $1564 $1565 Comparison of Propofol Sedation Versus Conscious Sedation During Endosonography Devjit S. Nayar, Martin Feuerman, Lawrence Scheinberg, Frank Gress A Randomized Prospective Trial Comparing Different Regimens of Oral Sodium Phosphate and Polyethylene Glycol Solution for Colonoscopy Preparation Emilie Jolicoeur, Aaaa Rostom, Sylvie Gregoire, Dilip Patel, Catherine Dube, Nay Saloojee, Cathy Lowe Moderate-Level Sedation During Endoscopy Using Low- Dose Propofol, Midazolam and an Opioid Lawrence B. Cohen, Charles D. Hightower, Daniel A. Wood, Kenneth M. Miller, James Aisenberg Non-anesthetist Administered Propofol for ERCP; Efficacy, Safety Profile and Side Effect : A Prospective Randomized Trial Pradermchai Kongkam, Bubpha Pomphisarn, Rungsun Rerknimitr A Prospective Randomised Single Blind Comparison of Three Methods of Bowel Preparation for Out-patient Flexible Sigmoidoscopy Anand L. Gidwani, Ragai R. Makar, Daphne Garrett, Robert Gilliland Treatment Efficacy and Safety Related to the Use of Propofol vs. Conventional Sedation in the Performance of Colonoscopy: A Meta-Analysis of Published Randomized Controlled Trials Neena S. Abraham, Maitreyi Raman, Kara Thompson Predictors of Oxygen Desaturation During Routine Gastrointestinal Endoscopy Timothy Cassidy, Eric Lawitz, Peter Kobes, Richard Shaffer, Esther Sutton, Linda Johnson, Donna Jones, Jeannette Turullols, Mark Jeffries $1566 $1567 $1568 $1569 $1570 S1571 $1572 S1573 $1574 $1575 S1576 S1577 $1578 Comparison of a New Bispectral Index (BIS) Algorithm to Modified Observer's Assessment of Alertness/ Sedation (MOAA/S) Scale in Moderate Sedation (MS) Sandeep Patel, John Vargo, Patricia Trolli, John Dumot, Darwin Conwell, Farah Khandwala, Gregory Zuccaro Randomized Controlled Colonoscopy Preparation Trial Comparing a Dose of Magnesium Citrate Plus 2-Liters of PEG-electrolyte Solution (PEG-ELS) Versus Standard 4-Liter PEG-ELS Samer H. A1-Shurieki, John B. Marshall A New 2 Litre Gut Lavage Solution : Results of a Prospective Randomised Multicentre Controlled Trial Comparing a PEG + Ascorbic Acid Solution Versus a Sodium Phosphate Solution Marc Barthet, Thierry Ponchon, Benoit Coffin, Main Bitoun, Cecile Dugue, Marc Halphen Correlation of Patient Satisfaction to Sedation Levels Detected by Bispectral Index (BIS) Using Moderate Sedation (MS) Sandeep Patel, John Vargo, Patricia Trolli, John Dumot, Darwin Conwell, Farah Khandwala, Gregory Zuccaro BIS Monitoring Predicts Recovery Time in Patients Receiving Intraprocedural Midazolam During Endoscopy Roger D. Mitty, Peter L. Moses, Douglas K. Pleskow Use of Bispectral Index Monitor (BIS) to Follow Depth of Sedation in Patients Undergoing Colonoscopy with Propofol Sedation Gregory S. Lesser, Robert Friedman, Edward Deal. E',I/./L/ Berberian, Steven R. Peikm, Adam B. Elfant Usefulness of Shakuyaku-kanzoh-to (TJ-68), a llcrbal Medicine, as an Antispasmodic Agent by Direct Spraying During Colonoscopy Masato Ai, Taketo Yatnaguchi, Takeo Odaka, Hilo31n>u Saisho A Comparison of Glucagon Versus Scopolamine Butylbromide as Premedicaton for Colonoscopy in Unsedated Patients Ichiro Yoshikawa, Masahiro Yamasaki. Nla>a>hi T,~<u<hi Mitsuo Tashiro, Takuji Yamasaki, Keiichiro Kume. Akit~.3~i Tabaru, Makoto Otsuki B1S Values Correlate with Clinical Sedation Scores During Midazolam/Narcotic or Propofol Sedation for Endoscopy Peter L. Moses, John J. Vargo, Roger D. Mitty, Douglas K. Pleskow, John A. Walker, Douglas K. Rex Receiver Operating Characteristics (ROC) of a Novel Bispectral Index Monitoring (BIS) Algorithm for Procedural Sedation with Opioid/Midazolam (O/M) vs Propofol(P) John J. Vargo, Peter L. Moses, Douglas K. Pleskow, Douglas K. Rex, Roger D. Mitty, John A. Walker Bispectral Index (BIS) Monitoring to Evaluate Level of Conscious Sedation for Outpatient EUS Procedures Gordon C. Hunt, Mary Lee Krinsky, John G. Kuldau, Mark S. Lemert, John McCarren, Thomas J. Savides Non-lntubated Capnography Is an Earlier Indicator of Hypoventilation Than Pulse Oximeter During Sedation for Colonoscopy Hiroshi Arakawa, Mitsuru Kaise, Hisao Tajiri, Kimio Isshi, Shouichi Saito, Takeshi Suzuki, Tomohiro Kato A Prospective Study to Assess the Efficacy and Patient Satisfaction of Three Bowel Preparations for Colonoscopy Roderick Rapier, Carmela Houston P-139

29 POSTER SESSIONS--CLINICAL SCIENCE U N MAY 16 > S1579 S1580 $1581 $1582 $1583 S1584 $1585 $1586 S1587 A Changing Landscape of Practice Patterns Regarding Unsedated Endoscopy and Propofol Use: A National Survey Ashley L. Faulx, Stacie Vela, Ananya Das, Gregory Cooper, Gerard Isenberg, Michael V. Sivak Jr., Terrell Clarence, Kenneth Wang, Amitabh Chak Safety, Efficacy and Tolerability of a Three-dose Regimen of Orally Administered Aqueous Sodium Phosphate for Colonic Cleansing Prior to Colonoscopy Robert L. Barclay Cardiopulmonary Complications with Non- Anesthesiologist-Administered Propofol vs. Standard Sedation: The CORI Experience John J. Vargo II, Glenn M. Eisen, Douglas O. Faigel, Jennifer Holub, David A. Lieberman The Demographics of Propofol-Mediated Endoscopy: The CORI Experience John J. Vargo II, Glenn M. Eisen, Doulgas O. Faigel, Jennifer Holub, David A. Lieberman Efficacy and Safety of an Oral Standard PEG Electrolytes Solution Compared to a Sodium Phosphate Solution in the Preparation of Patient for Colonoscopy Jean Francois Rey, Jean Stephane Delmotte, Daniel Gorce, Jean Luc Larpent, Stephane Mathieu, Philippe Gamier, Helene Mathiex-Fortunet, Jean Francois Flejou Is Patient Acceptability of Oral Sodium Phosphate as Preparation for Colonoscopy as Good as Is Claimed? Amro Salem, David Underwood, William Dicky, Daphne Garret< Paul Neilly, Robert Gilliland The Effects of Stress Coping Profiles and a Distraction/ Relaxation Intervention on Patient Acceptance of Colonic Cleansing for Colonoscopy Robert L. Barclay Intravenous Atropine as Pre-Medication for Upper Gastrointestinal Endoscopy: Re-evaluation of Its Utility Andy Li, Wendy Williams, Richard Thompson Sedation Without Anesthesiologist in 5250 Endoscopic Procedures: Midazolam vs. Midazolam + Dolantine vs. Propofol Ferran Gonzalez-Huix, Xavier Aldeguer, Esther Fort, Elisabet Salinas, Montserrat Figa, Manuela Hombrados, Rosa Chavero, Doroteo Acero ASGE Poster Session AM-5:00 PM Hall F OUTCOMES S1588 $1589 $1590 Development of an Instrument to Predict Endoscopic Tolerance Luis R. Pena, Houssam Mardini, Nicholas Nickl Development of a Decision Board to Elicit Patient Preferences for Palliation of Dysphagia due to Unresectable Esophageal Cancer Charles B. Evans, Leslie Nelson, Tamir Ben-Menachem Celecoxib Relieves Periprocedural Arthritis Pain in Patients Undergoing Colonoscopy Rohini Vii, Mark McCoy, Gurkirpal Singh, George Triadafilopoulos ASGE Poster Session AM-5:00 PM Hall F OUTCOMES Clinical Implications of the Extent of Invasion of T3 S1591 Esophageal Cancer as Determined by Endoscopic Ultrasound Tony E. Yusuf, Gavin C. Harewood, Jonathan E. Claim Michael J. Levy, Kenneth K Wang, Mark D. Topazian, Elizabeth Rajan Follow-up Endoscopy After Total Gastrectomy for $1592 Gastric Cancer Nam Cheol Hwang, Jun Haeng Lee Risk Factors Associated with Colonoscopic Perforation $1593 Jack I. Ramage Jr., Scott W. Grisolano, Bret T. Petersen, Kenneth W. Schroeder, Beverly J. Ott, Christopher J. Gostout Does Indication for Colonoscopy Affect Completion? An S1594 Examination of Colonoscopy Completion Rates Within a Large National Database James Nachiondo, Jennifer Holub, Atif Zaman, Glenn Eisen, Douglas Faigel Long Term Outcome of Biliary and Duodenal Stenting $1595 in Palliative Treatment of Patients with Unresectable Pancreatic Adenocarcinoma Frederique Maire, Philippe Ponsot, Alain Aubert, Dermot Otoole, Olivia Hentic, Philippe Lew, Philippe Ruszniewski, Pascal Hammel Risk of Significant Endoscopic Findings in Patients with S1596 Constipation James Fink, Glenn Eisen, Jennifer Holub, Kandice Knlgge Appropriate Use of Colonoscopy and Risk of Missing $1597 Colorectal Neoplasia Gianluca Bersani, Angelo Rossi, Giorgio Ricci, Alessandra Suzzi, Enrico Ricci, Claudio Cortini, Danilo Baroncini, Paolo Cioccolini, Vittorio Alvisi Is Upper Gastrointestinal Endoscopy Necessary $1598 Following a Normal Barium Swallow for Evaluation of Dysphagia? Stuart Flanagan, Tony Tham Diagnostic Yield of Colonoscopy for the Evaluation of $1599 Isolated Abdominal Pain Kevin C. Yee, John P. Cello, James Ostroff The Role of Therapeutic Endoscopy for Postoperative $1600 Management of Obstructive Symptoms After Hand Assisted Roux-Eu-Y-Gastric Bypass Kristoffel R. Dumon, David Metz, Michael L. Kochman, Noel N. Williams Do We Perform a Colonoscopy for Haemorrhoidal S1601 Bleeding? Francois Agret, Stephane Nahon, Pierre Lahmek, Bruno Lesgourgues, Thierry Tuszynski, Nicolas Delas ASGE Poster Session AM-5:00 PM Hall F OUTCOMES $1602 Cost-Effective Analysis of Gastric Cancer Screening in Japan Kenji Kobayashi, Tetsuya Mine P-140

30 POSTER SESSIONSmCLINICAL SCIENCE $1603 $1604 $1605 $1606 $1607 Photodynamic Therapy (PDT) for Barrett's Esophagus with High-Grade Dysplasia (BE + HGD): Cost- Effectiveness Model with Probabilistic Sensitivity Analysis Dan Comay, Gord Blackhouse, Ron Goeree, David Armstrong, John K. Marshall Cost-effectiveness of Capsule Endoscopy in Diagnosing Obscure Gastrointestinal Bleeding: An International Comparison Elvira Mueller, Bjoem Schwander, Rito Bergemann The Optimal Utilization of EUS in Pancreatic Cancer Staging Ali A. Siddiqui, William M. Tiemey Economic Evaluation of Wireless Capsule Endoscopy in Diagnosing Crohn's Disease Nell I. Goldfarb, Laura Pizzi, Christopher Salvador, Vanja Sikirica, Joseph P. Fuhr Jr. A Cost-Minimization Analysis of Alternative Strategies in Diagnosing Pancreatic Cancer Victor K. Chen, Miguel R. Arguedas, Meredith L. Kilgore, Mohamad A. Eloubeidi ASGE Poster Session AM-5:00 PM OUTCOMES S1608 $1609 S1610 S1611 $1612 S1613 S1614 Hall F Clinical Impact of Endoscopic Ultrasound (EUS) - A Prospective Study Andre Chong, Paul Desmond, Robert Chen Long Term Outcome of Endoscopic Management of Biliary Strictures Following Liver Transplantation Rajah S. Singh, Rafat S. Rizk, Kris V. Kowdley, Michael B. Kimmey Recent or Current GI Bleeding: AVMs Must Be Obliterated When Detected on Endoscopy. A Long-Term Follow-Up Study Kashyap N. Katwala, Stephen J. Sontag Endoscopic Evaluation and Treatment of Ampullary Tumors Michel Kahaleh, Vanessa M. Shami, Cynthia Yoshida, Christopher A. Moskaluk, Reid B. Adams, Paul Yeaton A Prospective Study of Colonoscopy Completion Rates for a Single Endoscopy Service Within a University Teaching Hospital Diarmuid S. Manning, Gayle Bennett, Suzi Clarke, Richard Walsh, Hugh E. Mulcahy The German Sphincterotomy Registry. A Voluntary Quality Assurance Project Matthias Maier, Christian Ell, Franz Hartmann, Ralf Jakobs, Franziska Plath, Thomas Roesch, Alexander Bachor Influence of Hypochlorhydria on Bacterial Overgrowth in the Proximal Small Intestine Yoshihisa Urita, Yoshinori Kikuchi, Kazuo Hike, Naotaka Torii, Eiko Kanda, Hidenori Kurakata, Masahiko Sasajima, Motonobu Ozaki, Kazumasa Miki ASGE Poster Session AM-5:00 PM Hall F PEDIATRICS S1615 S1616 S1617 S1618 Effectiveness of Prolonged ph Monitoring Using a Catheter-Free System in Children Undergoing Upper Endoscopy Toba Weinstein, Jeremiah Levine Use of ERCP in Management of Pediatric Patients: Indications, Findings, Therapies, and Complications Chfliang Cheng, Evan L Fogel, Stuart Sherman, Lee McHenry, James L. Watkins, Joseph F. Fitzgerald, Joseph M. Croffie, Sandeep K Gupta, Glen A. Lehman Incidence of Infantile and Familial GER in Children with Gastroesophageal Reflux Disease (GERD) Vasundhara Tolia, Lynette Essenbacher, Kim Boyer, Joel Ager Gastroesophageal Reflux Disease (GER) Questionnaire to Assess Quality of Life (QOL) in Patients and Parents Vasundhara Tolia, Lynette Essenmacher, Kim Boyer, Joel Ager ASGE Poster Session AM-5:00 PM Hall F PEDIATRICS Endoscopy and Children: Dealing with Fears $1619 Ane 1. Linden, Suzana Muller ASGE Poster Session AM-5:00 PM H~dl / PEDIATRICS S1620 S1621 S1622 Methods in the Development of a Muhidimensional Measure for Recurrent Abdominal Pain in Children (MMRAP): A Population-Based study Hoda M. Malaty, Suhaib A. Abudayyeh, Kimberly J. O'Malley, Mark A. Gilger, David Y. Graham, Michael J. Wilsey, Linda Rabeneck Fellow Perceptions of Computer-Based Endoscopy Simulators vs. Actual Procedures for Training Purposes Laurie N. Fishman, Jenifer R. Lightdale, Adrienne R. Newburg, Leonardo Villegas, Victor L. Fox Patient Reported Complications Following Pediatric Outpatient Colonoscopy and Flexible Sigmoidoscopy Steven J. Steiner, Marian D. Pfefferkorn, Joseph F. Fitzgerald ASGE Poster Session AM-5:00 PM Hall F PEDIATRICS S1623 S1624 Endoscopic Management of Duodenal Webs in Infants Nelson Garcia Jr., Satinder Gill, Martin Graham, Campbell Harris III, Alvin M. Zfass Endoscopic Manifestations of Erosive Esophagitis in Children Mark A. Gilger, Hashem B. El-Scrag, Craig L. Dietrich, Benjamin D. Gold, Eric G. Hassall P-141

31 ASGE Poster Session AM-5:00 PM Hall F PEDIATRICS LAPEG (Laparoscopic Assisted Percutaneous Endoscopic $1625 Gastrostomy): Towards a Safer Percutaneous Endoscopic Gastrostomy Placement Koorosh Kooros, Alejandro F. Flores, Marc S. Lessin, Brian F. Gilchrist One Hundred Fourteen Experiences of ERCP in S1626 Children Sun Yeon Lee, Soo Hee Chang, Kyung Mo Kim EUS in the Diagnosis and Management of Esophageal $1627 Pathology in Children Antonio Quiros, Shiro Urayama POSTER SESSIONSmCLINICAL SCIENCE ASGE Poster Session AM-5:00 PM Hall F PEDIATRICS $1628 Lymphoma of the Terminal Ileum Presenting as Intussusception and Hematochezia Ramamurti Chandra, Katie P. Miller, Dennis Borochovitz P-142

32 ' POSTER SESSIONS~COMBINED SCIENCE COMBINED SCIENCE AASLD Poster Session Authors are required to be present during the Poster Session from 12:00-2:00 pro. Those posters identified as DDW Posters of Distinction have received review scores that place them within the top 10% of all posters. We encourage you to make them a priority as you visit the poster session. AM-5:00 PM Hail F Mortal Convention Center AASLD Poster Session AM-5:00 PM Hall F Mortal Convention Center HEPATIC FIBROSIS $1638 Intrahepatic Gene Expression Profiles and Alpha- Smooth Muscle Actin Patterns in Hepatitis C Virus (HCV)-Induced Fibrosis Daryl T.Y. Lau, Bruce A. Luxon, Shu-Yuan Xiao, Michael Beard, Stanley M. Lemon ACUTE LIVER FAILURE An Antisense RNA to a Novel Gene Fgl2 and Its $1629 Therapeutic Effects in vitro and in vivo in Fulminant Viral Hepatits in Mice Qin Ning, Chuanlong Zhu, Yi Sun, Weiming Yam Dong Xi, Gary Le W, Xiaoping Luo -! ' Histamine Reduces Pro-Inflammatory Cytokines and $i630 Increases Survival in LPS-Induced Liver Injury After Partial Hepatectomy in Rats Stephen C. Hornyak, Adrian V. Radi, Kurt R. Gehlsen, Tapio Haaparanta Portal and Systemic Distribution of Benzodiazepines in i $1631 Thioacetamide- nduced Liver Failure Rats Justin H. Nguyen Testing the Putative Role of Parvovirus B19 or Hepatitis $1632 E Virus in Acute Liver Failure in the U.S William M. Lee, Kevin E. Brown, Neal S. Young, Susan } Wong, Jennifer D. Webster, George J. Dawson, Robert Fontana, Lorenzo Rossaro, R. Todd Stravitz, Julie Poison Screening for Wilson Disease in Acute Liver Failure by $1633 Serum Testing: A Comparison of Currently Used Tests Jessica D. Korman, Irene Volenberg, Jody Balko, Joe Webster, Frank V. Schiodt, William M. Lee, Michael L. Schilsky, The Acute Liver Failure Study Group Acute Liver Failure Patients Treated with Bioartificial $1634 Porcine Liver: Analysis of the Humoral Immune Response Against Pig Hepatocytes Angeles Baqueriz O, Veneta Kirilova, Ian Williamson, Ova Oakley, Henk-Jan Schuurman, Clive Patience, Achilles Demetriou, Ronald W. Busuttil, Christopher Shackleton MARS Versus Prometheus: Comparison of Clearances as S1635 a Measure of Efficiency in Two Different Liver Detoxification Devices Peter Krisper, Rudolf Stauber, Bernd Haditsch, Michael Trauner, Herwig Holzer, Daniel Schneditz AASLD Poster Session AM-5:00 PM Hall F Mortal Convention Center EXPERIMENTAL TRANSPLANTATION PRESERVATION, IS~HEMIA REPERFUSION The New Method of Hepatocyte Cryopreservation Using Non-metabolizable Glucose Compounds Keishi Sugimachi, Mehmet Toner The Mitochondrial Permeability Transition and $1637 Subsequent Caspase Activation Mediate Ischaemia- Reperfusion Injury to Human Liver Ian Currie, Stephen McNally, Ewan Harrison, Nick Wheelhouse, James Garden, Rowan Parks, James Ross $1639 $1640 S1641 S1642 $1643 $1644 $1645 S 1646 S1647 $1648 An Improved Biomarker Panel (FIBROSpect II) for Differentiating Mild from More Severe Liver Fibrosis in Chronic HCV Patients Esther Oh, Katie Smith, Keyur Patel, Stuart Gordon, Jean- Michel Pawlotsky, Ira Jacobson, John G. McHutchison Nitric Oxide Prevents Ongoing Thioacetamide-induced Liver Fibrosis by Upregulation of TGF-beta Masking Protein Gene in the Rat Liver Naoyuki Chisato, Tom Kono, Mutsubu Sugawara, Yoshiaki Ebisawa, Toshiyuki Asama, Takaaki Osawa, Tatsuya Suzuki, Yurino Kashiwade, Shinichi Kasai The Heterogeneity of Fibrosis in Patients with NA~H v~. HCV Mark V. Galan, Fame:_ Haatoh, Neal S G<qd,lcin. ",tlxa~tt t Gordon Gene Expression Profile Associated with Activated Hepatic Stellate Cells: Implications for Hepatic Fibrosis J. Michael Estep, Linda O'Rcill)'. Kalen 5Lh]:uich <,~l<~l<]i'~< Grant, Janus Ong, James Piper, Johann jonsson. Vika> Chandhoke, Katie M. Smith, Zobair M. Youlqo%l The Common Functional C(-159)T Polymorphism of the LPS Receptor CD14 Does Not Influence the Disease Outcome in Patients with Chronic Hepatitis C Infection Marcus Muehlbauer, Cart]in Meiler, Nlonika J<,hann \tttdt Hartmann, Norbert \Vodartc. Juergen Schoelmerich < [au- Hellerbrand A Sensitive in vivo Marker of Hepatic Fibrogenesis Using 2H20 Labeling of Liver Collagen or Hydroxyproline James Gardner, Abraham Bautista Jr., Julie Stark, David Buffman, Marc Hellerstein, Scott Turner Prospective Evaluation of a Serum (FibroSpect II) Panel to Predict Fibrosis in Chronic HCV Patients Keyur Patel, David R. Nelson, Nezam Afdahl, Esther Oh, Katie Smith, John G. McHutchison, Don Rockey Expression Pattern and Potential Role of the Novel Liver Specific Melanoma Inhibitory Activity Gene 2 (MIA2) in Liver Fibrosis and Hepatocellular Carcinoma Claus Hellerbrand, Frauke Bataille, Jacqueline Schlegel, Arndt Hartmann, Marcus Muehlbauer, Juergen Schoelmerich, Anja K. Bosserhoff Distribution and Isoforms of Epimorphin in the Injured Liver by Carbon Tetrachloride in Mice Daisuke Segawa, Kouichi Miura, Takashi Goto, Ken-Ichiro Mikami, Shigetoshi Oshima, Kunio Nakane, Kazuo Yoneyama, Tomomi Shibuya, Daisuke Watanabe, Ei Kataoka, Sumio Watanabe Regulation of Liver Fibrosis by P2Y Nucleotide Receptors Jonathan A. Dranoff, Emma A. Kruglov, Jean Sevigny, Simon C. Robson, Marianna Gaca, Rebecca G. Wells Denotes DDW Poster of Distinction P-143

33 POSTER SESSIONS--COMBINED SCIENCE S U N D A Y MAY 16 AASLD Poster Session AM-5:00 PM Hall F HEPATITIS B Application of the 2001 AASLD Hepatitis B Practice S1649 Treatment Guidelines to Patients Presenting to a Tertiary Care Medical Center Ronald Lew, Nancy Reau, Donald Jensen Recent Epidemiology of Chronic Hepatitis B Infection in $1650 Lower Manhattan Christine T. Bang, Tamer N. Sargios, David Widjaja, Henry C. Bodenheimer Jr., Albert D. Min The ~3C-Caffeine Breath Test Distinguishes Cirrhosis in $1651 Chronic Hepatitis B Infection and Is Unaffected by Short-term Lamivudine Therapy Gordon Park, Peter Katelaris, Brian Jones, Francis Scow, David Le Couteur, Meng Ngu Efficacy of High Dose Hepatitis B Vaccine (80Dg) in $1652 Chronic Liver Disease Asad Aziz, Shilun D. Li, Saad Aziz, Abhinandana Anantharaju, Loretta Murphy, Nancy Leone, Marc Kennedy, David H. Van Thiel Cirrhosis and Diabetes Mellitus Reduce High Dose S1653 Hepatitis B Vaccine (80mcg) Responses Shilun D. Li, Asad Aziz, Saad Aziz, Abhinandana Anantharaju, Loretta Murphy, Nancy Leone, Marc Kennedy, David Van Thiel S1654 $1655 $1656 S1657 $1658 Evolution of the Core Promoter, Precore and Core Gene Mutations of Hepatitis B Virus During Lamivudine Therapy in Patients with Chronic Hepatitis B Sun Suk Kim, Hwang Yu Jin, Kwang An Kwon, Moon Gi Chung, Dong Kyun Park, Yeon Suk Kim, So Young Kwon, Yu Kyung Kim, Duck Joo Choi, Ju Hyun Kim Sequential Therapy with Lamivudine and Interferon is Superior to Lamivudine Monotherapy in Patients With HbeAg Positive Chronic Hepatitis Hiroshi Watanabe Influence of the Hepatitis B Virus X Protein on Cellular and Viral Gene Expression Charles R. Madden, Betty L. Slagle Relation Between Core Gene Mutations and lntrahepatic HBcAg Expression in Young Adults with Perinatally Acquired Chronic Hepatitis B Infection Tae Hyeon Kim, Suck Chei Choi, Joo fin Yeom, Yong-Ho Nab, Haak Chul Kim, Guem Suk Seo, Sang-Wook Kim, Yong Sung Kim Molecular Epidemiology and Phylogenetic Analysis of Hepatitis B Virus (HBV) Isolated Subjects from Iran Mohammad Reza Zali, Mohammad Azizi, Samad Amini- Bavil-Olyaee, Ramin Sarrami Foroshani, Ahmad Adeli, Babak Noori Nayer AASLD Poster Session AM-5:00 PM Hall F METABOLIC LIVER DISEASES $1659 Blocking Nrampl Expression in Macrophage Dramatically Decreased ATP-Dependant Iron Transport Yingda Wang, Koji Abe, Christopher Ferris S1660 S1661 $1662 S1663 The Ancestral Haplotype Is Not Associated with an Enhanced Risk of Developing Iron Overload in Hereditary Haemochromatosis: Evidence from Families Studied in South Wales Anne McCune, Kymberley Carter, Mark Worwood, David Ravine, Helen Jackson, David Hutton Alcohol: A Fibrogenic Cocktail in Genetic Haemochromatosis? Ferga C. Gleeson, Eleanor Ryan, Sharon Barrett, John Crowe Wilson Disease in Septuganerian Siblings: Raising the Bar for Diagnosis Aftab Ala, George Brewer, Jimo Boi~igin, Arnold Rochwarger, Michael Schilsky Copper Related Toxic Effects on Cellular Protein Metabolism Katrin Merker, Doreen Hapke, Kristian Reckzeh, Herbert Lochs, Tilman Grune, Hartmut Schmidt AM-5:00 PM Hall F Sponsored by: AGA; Liver and Biliary CLINICAL BILIARY GALLSTONE DISEASES AND GALLSTONE PATHOGENESIS S1664 S1665 S1666 $1667 $1668 $1669 $1670 Small Gallbladder Stones, Good Gallbladder Motility and Fast Crystallization Are Major Risk Factors for Acute Pancreatitis Niels G. Venneman, Willem Renooij, Peter M. Go, lvo A. M. J. Broeders, Gerard P. vanberge-henegouwen, Karel J. van Erpecum Incidence, Natural History, and Risk Factors for Biliary Sludge and Stones During Pregnancy Cynthia W. Ko, Shirley A. A. Beresford, Scott J. Schulte, Alvin M. Matsumoto, Sum P. Lee Haplotypes of the ABCG5/G8 Genes Encoding the Hepatocanalicular Cholesterol Transporter Are Associated with Cholecystolithiasis H. E. Wasmuth, Nahum Mendez-Sanchez, N. Rahbar- Tabrizi, Hanns-Ulrich U. Marschall, Henning Wittenburg, A. C. King-Martinez, Misael Uribe, Siegfried Matern, Frank Lammert Orlistat Impairs Gallbladder Emptying Through Inhibition of CCK Release in Response to a Test Meal Mark Ellrichmann, Frank Schmitz, Jan M. Otte, Gabriele Brunke, Karl-H. Herzig, Wolfgang E. Schmidt ABCA1 Expression of Gallbladder Tissue in Gallbladder Diseases Ho-Soon Choi, Oh Yong Lee, Dong-Soo Han, Joo-Hyun Sohn, Joon-Soo Hahm, Hyun Joo Jang, Jin Lee, Chang Soo Eun, Rahul Kuver, Sum Lee Natural History of Gallstone Disease: Expectant Management or Active Treatment? Results from a Population-based Cohort Study (the Multicenter Italian Study of Cholelitiasis, MICOL) Davide Festi, Antonio Colecchia, Enrico Roda, Adolfo Attili, Paola Loria, Nicola Carulli, Simona Capodicasa, Ferdinando Romano Genetic and Environmental Influences on Symptomatic Gallstone Disease: A Swedish Twin Study of 43,141 Twin Pairs Despina Katsika, Andrej Grjibovski, Curt Einarsson, Frank Lammert, Paul Lichtenstein, Harms-Ulrich Marschall P Denotes DDW Poster of Distinction

34 : 6:00 : Si671 I; S1672 k S1673 ~ S1674!~ S:oo :' $1675 T Increased Contractility of the Inflamed Human Gallbladder Is Mediated via Bradykinin B1 Receptor Activation Roberto De Giorgio, Marcello Trevisani, Barbara Giovanni, Vincenzo Stanghellini, Piero Geppetti, Roberto Corinaldesi POSTER SESSIONS~COMBINED SCIENCE Gilbert's Syndrome and Choledocholithiasis Michelle C. Beilstein, Nuzhat A. Ahmad, Gregory G. Ginsberg, Michael L. Kochman, Colleen M. Brensinger, Eric Rappaport, K. Rajender Reddy, William B. Long Effect of Chronic Administration of Ursodeoxycholic Acid on Gallbladder and Gastro-Intestinal Motility in Gallstone Patients and Healthy Controls Antonio Colecchia, Lorenza Sandri, Patrizia Simoni, Francesco Azzaroli, Amanda Vestito, Simona Capodicasa, Giuseppe Mazzella, Aldo Roda, Enrico Roda, Davide Festi Association of Unconjugated Bilirubin with Microparticulates of Calcium Carbonate Synthesized in a Phosphotidyl Choline Vesicle Solution Z. L. Yang, Roger D. Soloway, J. Chao, X. B. Liu, L. Zhang, F. Wang, J.-G. Wu High Association Between Cardiovascular Disease and Gallstone Disease Nahum Mendez-Sanchez, Jesus Bahena-Aponte, Daniel Motola-Kuba, Karla Sanchez-Lara, Norberto Chavez-Tapia, Martha H. Ramos, Misael Uribe i~,~ AM-5:00 PM Hall F Sponsored by: Esophageal, Gastric and Duodenal Disorders BARRETT'S ESOPHAGUS: PATHOGENESIS 8:.00 S S ~ ; S1678 '8 S S S1681 S1682 Lumen-to-Surface ph Gradient in Barrett's Esophagus Solange M. Abdulnour-Nakhoul, Roy C. Orlando Defective TGF[~ Signalling Throughout the Barrett's Metaplasia-Dysplasia-Adenocarcinoma Sequence Benjamin A. Onwuegbusi, Rebecca C. Fitzgerald An Increase in Cytosolic Calcium Mediates Acid- Induced Prostaglandin Ez Production in Barrett's Esophagus Weibiao Cao, Jack R. Wands, Jose Behar Reactive Nitrogen Species Derived from Reflux of Duodenal Contents Play an Important Role in the Development of Esophageal Adenocarcinoma in a New Rat Reflux Model Ken-Ichi Mukaisho, Takanori Hattori Novel in vitro Model for Studying the Development and Neoplastic Progression of Barrett's Esophagus Rachana R. Maniar, Ruben D. Ramirez, Carmela P. Morales, S. D. Dimitrijevich, Stuart J. Spechler, Rhonda F. Souza Esophageal Bilirubin Exposure Is Not Increased Following Cholecystectomy Martin Fein, Joern Maroske, Marco Sailer CDX-1 and CDX-2 Are Differentially Expressed in Cardia Mucosa and Columnar-Lined Epithelium of Patients with Barrett's-Esophagus Mark Juhasz, Ulrich Peitz, Michael Vieth, Zsoh Tulassay, Matthias Ebert, Peter Malfertheiner t $1683 $1684 $1685 $1686 $1687 S1688 $1689 $1690 S1691 $1692 $1693 $1694 $1695 Identification of Gastroduodenal Reflux Related Signaling in Barretts Esophagus Cathrine DeMars, Navtej S. Buttar, Raul Urrutia, Kenneth K. Wang, Louis-Michel Wong Kee Song, Vivek Mittal, Sarah M. Papenfuss, Marlys Anderson, Lori Lutzke, Amanda Ross Acid and Acidified Bile Salts Increase Oxidant Production in Barrett's Esophagus Linda A. Feagins, Lance S. Terada, Kenneth Shewmake, Carmela P. Morales, Stuart J. Spechler, Rhonda F. Souza Activation of NF-KB/IL-6/STAT-3 Pathway in Esophageal Cells by Bile Acids and Low ph Katerina Dvorakova, Claire M. Payne, Melissa Chavaria, Terry Landowski, Tara Margelofski, Cara Crowley-Weber, Harris Bernstein, Carol Bemstein, Harinder Garewal Prevalence and Incidence of Barrett's Adenocarcinoma Among Patients with Reflux Disease in a Large Prospective Cohort Study Michael Vieth, Andreas Leodolter, Michael Kulig, Emma Naucler, Tore Lind, Daniel Jaspersen, Stefan N. Willich, Joachim Labenz, Peter Malfertheiner, Manfred Stoke Global Gene Expression in Barrett's Esophagus Using Microarrays Hashem B. E1-Serag, Rhonda Souza, Leif Peterson, Petra Pilgrim, Gretchen Darlington GERD is Associated with Shortened Telomeres in the Distal Squamous Esophagus Tisha Dineen, Ruben D. Ramirez, Edward Lec. Yu~nan Shen, Xi Zhang, Charles Owen, Carmcla MoraL-,, Rh,,tnd,~ Souza, Stuart J. Spechler Barrett's Esophagus is Associated with an Increased Epithelial Inflammation Leon M. G Moons, Johannes G. Kusters, Ernst j Ktdpct-. Wendy Tra, Herman van Dekken, Arnoud H ki van kl:c~ Peter D. Siersema Down-Regulation of the Homeobox Gene CDX2 b} an Acidified Bile Pulse in an in vitro Model oof BarreU~s Oesophagus Neff Kapoor, Lugang Yu, Keith Bodger Conjugated but Not Unconjugated Bile Acids Induce Time-Dependent Increases in Proliferation in Barrett's Esophagus ex vivo Cultures Peter D. Siersema, Baljeet S. Kaur, Diana M. Toivola, Alan F. Hofmann, M. Bishr Omary, Ernst J. Kuipers, George Triadafilopoulos A Novel External Esophageal Perfusion Rat Model for Reflux Esophagitis Yan Li, Susan F. Ellis, Robert C. Martin, Mukunda B. Ray, Whitney Jones, John M. Wo Hypermethylation Silences GATA4 Gene and Occurs Early in the Tumorigenesis of Barrett's Esophagus Hongzhi Zou, Jonathan J. Harrington, David A. Ahlquist Low ph Results in Co-ordinate Regulation of Gene Expression in Esophageal Cells Shane Duggan, Mohammed Abdel-Latif, Edward Fox, William Gallagher, John Reynolds, Dermot Kelleher Genomic Aberrations in Barrett's Esophagus (BE)- Associated Dysplasia-Carcinoma Sequence: An Array- Based Comparative Genomic Hybridization (A-CGH) Study Anna Siva, Marek Skacel, Dina Kandil, Graham Casey, Jennifer A. Brainard, Thomas W. Rice, Mary P. Bronner, John R. Goldblum, Raymond R. Tubbs, Gary W. Fail Denotes DDW Poster of Distinction P-145

35 POSTER SESSIONS--COMBINED SCIENCE S U N D A Y MAY 16 $1696 S1697 S1698 S1699 S1700 $1701 S1702 $1703 S1704 S1705 Post-Translational Suppression of Ornithine Decarboxylase by Peroxisome Proliferator-Activated Receptor-Gamma Ligand in Barrett'S Adenocarcinoma Cells Takashi Takashima, Yasuhiro Fujiwara, Masaki Hamaguchi, Eiji Sasaki, Toshio Watanabe, Kazunari Tominaga, Nobuhide Oshitani, Takayuki Matsumoto, Kazuhide Higuchi, Tetsuo Arakawa Acid Exposure Up-regulates Expression of a Colonic Epithelial Protein Present in BIC-1 Adenocarcinoma of Esophagus Cells and in a Colon Cancer Cell Line Jianying Liu, )(in Geng, David Beer, Kiron M. Das Increased Activation of STAT-3 in Patients with Barrett's Esophagus Katerina Dvorakova, Lois Ramsey, Richard Sampliner, Hana Holubec, Anil Prasad, Claire M. Payne, Harris Bernstein, Carol Bemstein, Harinder Garewal H.Pylori Activates Different Apoptotic Signaling Pathways in Barrett's-Derived Esophageal Adenocarcinoma Cells Depending Upon the Level of COX-2 Expression Brandon Barrett, Kathy Bacon, Brett Sheppard, Clifford Deveney, Michael Rutten Premature Opening of the LES Correlates with the Length of Barrett's Esophagus Eugene F. Tharalson, Rodney L. Akins, Francisco C. Ramirez, Michele A. Young Expression of the Intestinal Transcription Factor CDX2 in Non-Goblet Cells in Biopsies of Barrett Esophagus Liang Liu, Mahdis Rahmani, Mamoun Younes Patients Who Presently Do Not Smoke Have Longer Lengths of Barrett's Esophagus (BE) As Compared to Those Who Actively Smoke --a Multi-Center Survey Ronnie Fass, Colleen Green, William D. Chey, Michael P. Jones, Glenn M. Eisen, Michael Briseno, Harinder S. Garewal, Francisco C. Ramirez Histological and Genetic Characterisation of a Surgical Model of Esophageal Adenocarcinoma in the Rat Andrew Hindmarsh, Edward Cheong, Virginia Sams, Lazlo igali, Joanne F. Doleman, Nigel Belshaw, Elizabeth Lund, Michael Rhodes, fan T. Johnson Regulators of COX-2 Expression in Barrett's Oesophagus George F. Abouda, James P. Cotton, Joanne Darragh, John F. Dillon Early Detection of Intestinal Metaplasia at the GE Junction Without Histologic Barrett's Esophagus Using mab DAS-1 Manoj A. Shirodkar, Eric H. Shen, Sudha Nahar, Devang Patel, Ellen Ebert, Nadeem Baig, Aram Manoukian, Kiron M. Das AM-5:00 PM Hall F Sponsored by: Gastrointestinal Oncology TRANSLATIONAL RESEARCH I S1706 Sensitivity and Specificity of Microsatellite Instability (MSI) and Immunohistochemistry (IHC) as Prescreening Markers in HNPCC Suspected Patients Olivier Berthelet, Quin Wang, Marie-Odile Joly, Claire Thomas, Francoise Desseigne, Dominique Leroux, Fabienne Prieur, Jean-Yves Scoazec, Jean-Christophe Saurin S1707 $1708 S1709 S1710 S1711 S1712 $1713 S1714 S1715 S1716 S1717 S1718 Immunohistochemical Expression of [~-catenin, p53, bcl- 2 and COX-2 According to Macroscopic Morphology of Colorectal Adenomas Hyun A. Oh, Yeung Sung Kim, Moon Kwan Chung, Tae Nyeun Kim, Byung Ik Jang, Jun Hwan Kim, Young Kyung Bae Molecular Differences Between Sporadic Serrated and Conventional Colorectal Adenomas Kazuo Konishi, Toshiko Yamochi, Reiko Makino, Kazuhiro Kaneko, Taikan Yamamoto, Hisako Nozawa, Atsushi Katagiri, Yosuke Kumekawa, Michio Imawari Epigenetic Changes and MSI in Coloreetal Cancers from African Americans Hassan Ashktorab, Duane Smoot, Aiqiu Zhao, Marie N. Fidelia-Lambert, Haleh Farzanmehr, Mohsin Zafar, Rehana Begum, Bahram Momen, Linda M Hyland, Karin Berg, Christin laccobuia-danahukl, Ajay Goel, C. Richard C. Boland, John M. Carethers, Francis Giardiello Loss of PMS2 Protein Expression Is Not Infrequent in Colorectal Cancer Kaspar Truninger, Mirco Menigatti, Ritva Haider, Jan-Olaf Gebbers, Fridolin Bannwart, Anna Russell, Karl Heinimann, Huseyin Yurtsever, Joerg Neuweiler, Hans-Martin Riehle, Primo Schaer, Josef Jiricny, Giancarlo Marra Loss of Imprinting (LOI) of Insulin-Like Growth Factor (IGF)-2 in Background Normal Colonic Mucosa in Patients with Colorectal Cancer Jun'ichi Sasaki, Yutaka J. Kawamura, Toshihiko Tsukamoto, Fumio Konishi Expression of Macrophage Inhibitory Factor in Human Colorectal Cancer Stratified according to Microsatellite Instability Status Bingtuan Wang, He-Hong Ni, Kai Liu, Julio Faria Risk Factors for Lymph-Node IVlg~tases: A Prospective Study ~ K II Francisc~-~ ~n~rg, Demian A. F~l~[llg~l,t~'v~'is~uba, Gonzalo Soto, alvaro A. Z~li~lLWGl'6ria Aguayo, Concepcion Risueno, Paola Viviani, Guillermo Marshall, Guillermo Marshall Cyclooxygenase-2 Enhances Expression of Carcinoembryonic Antigen-Related Cell Adhesion Molecules (CEACAMs) on Human Colon Cancer Cell Takanobu lrie, Shingo Tsuji, Masahiko Tsujii, Satoshi Egawa, Masato Komori, Tsutomu Nishida, Masakazu Yasumaru, Hideki Iijima, Hiroaki Murata, Norio Hayashi, Sunao Kawano Analysis of Uncoupling Protein-2 Expression in Human Colon Cancer Masayoshi Horimoto, Murray B. Resnick, Tamako A. Konkin, Justin Routhier, Jack R. Wands, Gyorgy Baffy Genetic Polymorphisms in the CYP2C9 Enzyme and the Risk of Colorectal Adenoma Andrew T. Chan, Gregory J. Tranah, Edward L. Giovannucci, David J. Hunter, Charles S. Fuchs PPARF Pro 12 Ala Polymorphism and Colon Cancer Risk Temitope O. Keku, Robert C. Millikan, Joseph Galanko, Kendra Bowen, Elizabeth Hodgson, Jon S. Player, Allison Eaton, Chris Martin, Robert Sandier Role of Cytokine Gene Polymorphisms in Colorectal Cancer and Their Interaction with Aspirin Use Mairi MacArthur, Linda Sharp, Georgina L. Hold, Julian Little, Emad M. E1-Omar P Denotes DDW Poster of Distinction

36 r POSTER SESSIONS~COMBINED SCIENCE $1720 S1721 S1722 $1723 $1724 $1725,S1726 S1727 S1728 S1729 $ Epidemiology of Interleukin 1 Genetic Polymorphisms in the General Population Rocco M Zagari, Luigi Ricciardiello, Michele Baglioni, Cristian Bonvicini, Veronica Lunedei, Lorenzo Fuccio, Cristina Martuzzi, Enrico Roda, Franco Bazzoli The C677T Methylenetetrahydrofolate Reductase(MTHFR) Polymorphism Is Associated with Reduced MTHFR Expression in Colorectal Cancer Kellie Collins, Glen A. Doherty, Maw-Rose Sweeney, Sinead M. Byrne, Abdur Aftab, Elaine W. Kay, Frank E. Murray, Denis C. Shields Pilot Study on UDP-Glucuronosyltransferase Polymorphisms and Risk of Colorectal Adenomatous Polyps in African-Americans Hugo Pinillos, Peter Holt, Joshua Muscat, Philip Lazarus Gene-Expression Profile of the Normal Mucosa of Patients with Colorectal Cancer and of Normal Controls Identified by DNA Microarray Analysis Francesco Franceschi, Lucia Fini, Alberto Manno, Emilia Carloni, Maria A. Zocco, Simona di Caro, Diego Leo, Michele C. Santoro, Immacolata A. Cazzato, Nicolo Gentiloni Silveri, Aurelio Ptcctocchi, Claudio Coco, Giovanni B. Gasbarrini, Antonio Gasbarrini Diagnosis of Malignancy in Colon Biopsy Specimen by mrna Expression Profiling Orsolya Galamb, Ferenc Sipos Sr., Bela Molnar, Zsolt Tulassay Removal of Flat Colonic Lesions Is Supported by Gene Expression Profiling Analysis Anjali K. Morey, Shai Friedland, Mari Olsen, Roy Soetikno, Patrick Brown, Anson W. Lowe Tissue Array Profiling Reveals That the Cell Cycle Proteins, Ki67 and P16, May Predict Tumor Behavior in Gastrointestinal Carcinoids Mark Kidd, Robert Camp, Irvin M. Modlin Tissue Microarrays (TMA) For Gene Expression Analysis In Colorectal Carcinomas (CRC) Genevieve Monges, Severine Esteries, Christophe Ginestier, Emmannuelle Charafe-Jauffret, Francois Bertucct, Patrice Viens, Frederic Viret, Marc Giovannini, Jean-Robert Delpero, Danielle Parriaux, Danielle Birnbaum Gene-Expression Profile of Colorectal Adenocarcinoma Tissue Identified by Gene Microarray Analysis. Francesco Franceschi, Lucia Fini, Alberto Manno, Emilia Carloni, Maria A. Zocco, Simona di Caro, Diego Leo, Michele C. Santoro, Enrico C. Nista, Immacolata A. Cazzato, Nicolo Gentiloni Silveri, Aurelio Picciocchi, Claudio Coco, Giovanni Gasbarrini, Antonio Gasbarrini Human Neuroendocrine Tumor Cells Express Cold Sensitive TRPM8 Channels Stefan Mergler, Thomas Hath, Carsten Groetzinger, S. Kaiser, Peter Neuhaus, Wolf-Otto Bechstein, Bertram Wiedenmann Expression of CD44 Splice Variants and Tyrosine Kinase Receptor c-met Depends upon Growth and Differentiation Status in Colon Cancer Cells Ravinder Singh, Barry J. Campbell, Jonathan M. Rhodes Detection of APC and hpp1 Gene Methylation Using Rectal Brush Biopsy as an Alternative Approach for Bowel Research Rak John C. Mathers, Seamus Kelly, M Welfare, L Williams, L. Janssens AM-5:00 PM Hall F Sponsored by: Intestinal Disorders CELIAC DISEASE AND OTHER INTESTINAL DISORDERS $1731 $1732 S1733 $1734 $1735 S1736 $1737 $1738 $1739 $1740 $1741 HLA Class I-Restricted Gliadin Peptide Activates Small Intestinal Immune Response in in vitro Cultured Treated Coeliac Mucosa Giuseppe Mazzarella, Carmen Gianfrani, Rosita Stefanile, Virginia Salvati, Nicola Giardullo, Gaetano Iaquinto, Clementina Faruolo, Elena Cosentini, Riccardo Troncone, Salvatore Auricchio, Alessandro Sette Is Prolyl-Endopeptidase Effective in the Detoxification of Gliadin Peptides in Coeliac Disease? Tamara Matysiak-Budnik, Celine Candalh, Christophe Dugave, Christophe Cellier, Nadine Cerf-Bensussan, Martine Heyman Revisiting T Cell Abnormalities and Prognosis in Refractory Celiac Disease Kayode O. Olowe, Cezary Ciszewski, Xujun Wu, Bana Jabri, Govind Bhagat, Peter H. R. Green Celiac Disease (CD): Should Be Patients with Lymphocytic Enteritis (Marsh I Lesion) Be Treated with a Gluten-free Diet (GFD)? Maria Esteve, Fernando Fernandez Banare>. Mcrce Rosinach, Clarisa Gonzale_-, Carme Farrc, M,~llt>erral \[,/ta.~ Montse Forne, Jaume Casalot>, Jorge C I spmo>,~,rlt~l~/,~ Salas, Josep Maria Viver A Functional-Genetics Approach to Unravel Molecular Pathways in Celiac Disease Cisca Wijmenga, Martine van Belzen. Bedona Dio_-clach, Lude Franks, Alienke Mt,nsuur, Erica \'a~q O,,u ~I~//[l[l~ Wapenaar, Rodercik Houwen, Chris Mulder Gliadin-lnduced Oxidative Stress and Morphologic Damage in a Three-Dimensional Cell Culture Model Luca Elli, Ersilia Dolfini, [ eda Roncoroni, Maria Pia Colleoni, Barbara Costa, Vito Lorus~o. 5imona Rampotqi. Maria Letizia Falini, Maria Teresa Bardella Refractory Celiac Disease (RCD): Factors Associated with Overt Lymphomatous Transformation and Survival Cellier Christophe, Lecomte Thierry, Afchain Pauline, Verkarre Virginie, Cosnes Jacques, Lemann Marc, Bouhnik Yoram, Colombel Jean Frederic, Delchier Jean Charles, Brousse Nicole, Cerf-Bensussan Nadine Duodenal Surface Barrier is Altered in Coeliac Disease, and is Not Restored to Normal by Gluten-Free Diet Stefania Bertolazzi, Massimo Amato, Francesco Lanzarotto, Vincenzo Villanacci, Federica Benini, Alessandra Mora, Alberto Lanzini Dissociation Between Morphological and Functional Abnormalities in Untreated Coeliac Disease John W. O'Donohue, Puru Premchand, Deepak Joshi, Ian Forgacs, Mashal D. AI-Nawab, lngvar T. Bjarnason ICOS and CD28 Gene Polymorphisms and Celiac Disease Karen Brophy, Anthony Ryan, Conleth Feighery, Colm O'Morain, Nicholas Kennedy, Ramona McLoughlin, Fiona Stevens, Dermot Kelleher, Ross McManus HLA-DQ2 Dosing Might Predispose to Development of Refractory Celiac Disease (Type II) and EATL Bart Crusius, Marije Goerres, Muhammed Hadithi, Jos Meijer, Amado S. Pena, Chris Mulder Denotes DDW Poster of Distinction P-147

37 POSTER SESSIONS--COMBINED SCIENCE $1742 $1743 $1744 Can 18F-Fluoro-Deoxy-Glucose Positron Emission Tomography Be Useful in Detecting Enteropathy- $1754 Associated T-CeU Lymphoma in Refractory Celiac Disease? Muhammed Hadithi, Emile Comans, RoelHeijmans, Marie von Blomberg, Joost Oudejans, Otto Hoekstra, Chris Mulder $1755 Canadian Celiac Health Survey Connie M. Switzer, Ann B. Cranney, Ian D. Graham, J. Decker Butzner, Mohsin Rashid, Vernon D. Burrows, Marion Zarkadas, Shelley M. Case, Mavis K. Molloy, Ralph Warren $1756 Enzyme Therapy for Management of Celiac Disease Finlay A. Macrae, Hugh J. Comell, Joy Me/ny, Cathy Pizzey, Fiona Cook, Sandra Mason, Ted Stelmasiak IgA Anti-Actin Antibodies and Autoimmunity in Celiac Disease Emilia Sugai, Silvia Pedreira, Maria L. Moreno, Horacio Vazquez, Roberto Mazure, Fabio Nachman, Edgardo Smecuol, Sonia I. Niveloni, Eduardo Maurino, Julio C. Bai Celiac Disease Screening in First Degree Relatives: A Canadian Population Study Anshu Srivastiva, Tony Abboud, Marvin J. Fritzler, Jonathon B. Meddings, J. Decker Butzner Is Childhood Celiac Disease (CD) a Temporary or a Lifelong Disorder? Cellier Christophe, Grosdidier Etienne, Patey Natacha, Verkarre Virginie, Rault Dorothee, Matysiak Tamara, Mallamut Georgia, Cerf-Bensussan Nadine, Brousse Nicole, Schmitz Jacques p =J S U N D A Y MAY 16 $1745 $1746 S1747 $1748 $1749 $1750 $1751 $1752 $1753 Celiac Children Grow Up Carolina Ciacci, Paola Iovino, Daniela Amomso, Monica $1757 Siniscalchi, Raffaella Tortora, Assunta Di Gilio, Gabriele Mazzacca Immunogenicity and in vivo Toxicity of HMW Glutenins in Celiac Disease David Dewar, Emma Pollock, Wolfgang Engel, Julia Ellis, Massimo Amato, Herbert Wieser, Paul Ciclitira $1758 Intestinal Proteinase-Activated Receptor (PAR)-2 Is Up- 8 regulated in Active Celiac Disease and Co-Localizes with Zot/Zonulin Receptor Maria Grazia Clemente, Stefano De Virgilis, Maria Paola Musu, Paolo Usai, Patrizia Porqueddn, Lucia Cicotto, Carlo Massida, Alessio Fasano S1759 Sera of Patients with Celiac Disease and Neurological Disorders Evoke Mitochondrial-Dependent Apoptosis in a Neuroblastoma Cell Line Roberto De Giorgio, Elisabetta Cervio, Umberto Volta, Manuela Verri, Federica Boschi, Ornella Pastoris, Riccardo Vicini, Alessandro Agazzi, Barbara Giovanni, Giovanni S1760 Sarnelli, Fabrizio De Ponti, Vincenzo Stanghellini, Roberto Corinaldesi, Marcello Tonini Screening Patients with Hashimoto's Thyroiditis for Celiac Disease and Vice Versa Muhammed Hadithi, Hans de Boer, Louis Verschoor, Bart S1761 Crusius, Amando S. Pena, Jos Kerckhaert, Chris Mulder Intestinal Permeability in Long Term Follow-up of Celiac Patients on a Gluten Free Diet Donald Duerksen, Carrie Wilhem-Boyles, David Parry S1762 Management of Nonresponsive Celiac Disease David H. Dewar, Matthew W. Johnson, Julia Ellis, Paul J. Ciclitira S1763 Celiac Disease Case-Finding in Primary Care in North America. Preliminary Results of a Multicenter, Prospective Study Carlo Catassi, Otto Louis-Jacques, Debby A. Kryszak, Karoly Horvath, Lisa Medeiros, lvor Hill, Donald Duerksen, S1764 Sheila E. Crowe, Andrew R. Brown, Andrew Wolf, Anthony Vitelli, Walter Robison, James Moreci, Ashith Mally, Stephanie Colodny, Paul Hartley, Rajesh Saxena, Sridhar Patnam, Nathan Bennett, Briyce Palchick, Donna College, Varica Thomas, Cathy Brooks, Cathleen Paulin, Mike Volk, $1765 Agata Bednarz-Volk, Even Heald, Alessio Fasano Bone Mineral Density Changes in Treated Celiac Disease: Long Term Follow-up Julian R. F. Walters, Jennifer Field, Lucy Goddard, Orli Rhodes-Kendler, Linda Banks S1766 The Prevalence of Celiac Disease in Natrona County, Wyoming Kent D. Katz, Patricia Krause, Kim Attaway, Lucy Sullivan, Christopher Jones, Valerie Lathrop, Kristine Maggi, George Oveka, Nancy Neufeld, Judy Aurelius, Roger Budd, Joseph A. Murray Systematic Assessment of the Causes of Watery Chronic Diarrhea with Clinical Characteristics Suggesting Functional Disease Fernando Fernandez-Banares, Maria Esteve, Montserrat Alsina, Jaume Casalots, Carme Farre, Montse Buxeda, Montse* Forne, Jorge C. Espinos, Clarisa Gonzalez, Antonio Salas, Josep Maria Viver Characterization of Mycophenolate MofetiMnduced Intestinal Injury in Transplant Patients L. Heemskerk, I. Gan, Stefan Urbanski, V. Falck, K. McLaughlin, K. K Burak, S. Yilmaz, S. Seminowich, Gary Martin, Paul L. Beck Positive Celiac Serology in Patients With Abdominal Pain and Negative Small Bowel Biopsy Have Inflammatory Changes in the Small Bowel on Capsule Endoscopy Samuel N. Adler, Harold Jacob Antibiotic-associated Hemorrhagic Colitis Is Induced by Klebsiella Oxytoca in an in vivo Rat Model Christoph Hoegenauer, Cord Langner, Eckhard Beubler, Irmgard T. H. Lippe, Rudolf Schicho, Guenter J. Krejs, Thomas A. Hinterleitner Circulating Cytokine Profile Suggests a Role for Inflammation in Irritable Bowel Syndrome Mahesh P. Sharma, Vineet Ahuja, Vikas Sachdev The Spectrum of Segmental Colitis Associated with Diverticulosis Ioannis E. Koutroubakis, Pavlos Antoniou, Maria Tzardi, Elias Kouroumalis Hermansky-Pudlak Syndrome: Colitis Frequency in a Large Cohort of Patients Nadeem Hussain, David Geho, Martha Quezado, Dorett Sutherland, William Gahl, Peter Mannon Efficacy of Mesalamine lg HS vs. 500 mg BID Suppositories in Mild to Moderate Ulcerative Proctitis: A Multicenter Randomized Trial Mark Lamet, Theadore Ptak, Chrystian Dallaire, Umedchandra Shah, Maha Guindi, Jean Spenard, Danielle de Montigny Cytokine Imbalance in Patients with Irritable Bowel Syndrome and Response to Probiotic Therapy Liam O'Mahony, Mary Lucey, Jane McCarthy, Peter Kelly, Barry Kiely, John K. Collins, Fergus Shanahan, Eamonn Quigley P-148 ~ Denotes DDW Poster of Distinction

38 r $1767 S1768 S1769 S1770 $ S1772 POSTER SESSIONSICOMBINED SCIENCE Gastroduodenal and Intestinal Permeability in Patients Undergoing High-Dose Chemotherapy and Autologous $1778 Peripheral Blood Stem-Cell Transplantation (PBSCT) Renato Cannizzaro, Mariagrazia Michieli, Maurizio Rupolo, Armando Franceschin, Ettore Bidoli, Moreno Mazzuccato, Luciano Abbruzzese, Massimiliano Berretta, Umberto Tirelli Enhanced Chemokine Receptor 4 and Interleukin 6 S1779 mrna Expression in Patients with Cow's Milk Protein Sensitive Enteropathy Laura Paajanen, Jorma Kokkonen, Tuomo Karttunen, Tuula Tuure, Riitta Korpela, Outi Vaarala Efficacy of Mesalazine in the Treatment of Symptomatic Diverticular Disease Giovanni Aragona, Gioacchino Leandro, Libera Fanigliulo, S1780 Giulia M. Cavestro, Giuseppe Comparato, Lucas G. Cavallaro, Pierantonio Muzzetto, Angelo Franze', Francesco Di Mario Apoptotic Colopathy: New Subtype of Microscopic Colitis or Epiphenomenon? S1781 Darrell S. Pardi, Thomas C. Smyrk, Patricia Kammer, Herschel A. Carpenter, Joseph A. Murray Genetic Variation in the T Cell Regulatory Gene CTLa4 Is Associated with Early Onset Celiac Disease $1782 Karen A. Hunt, Dermot P. B. McGovern, Parveen J. Kumar, Subrata Ghosh, Simon P. L. Travis, Julian R. F. Wakers, Derek P. Jewell, Raymond J. Playford, David A. van Heel Effectiveness of Treatment in Patients with an Abnormal $1783 SeHCAT Scan Catherine E. Farrow, David Dunlop, John D. Linehan AM-5:00 PM Hall F S1784 Sponsored by: Intestinal Disorders INTESTINAL ISCHEMIA AND FREE RADICAL BIOLOGY S $1774 $1775 S1776 $1777 Endothelial Nitric Oxide Synthase (enos)-dependent Release of Calcitonin Gene-Related Peptide (CGRP) Triggers the Postischemic Anti-Inflammatory Effects of Ethanol Preconditioning (EPC) Kazuhiro Kamada, Taiji Yamaguchi, Patsy Carter, Toshikazu Yoshikawa, Ronald J. Korthuis Chronic Mesenteric lschemia: From Classic Abdominal Angina to Single- and Multivessel Disease; Experience in 102 Patients P. B. F. Mensink, J. J. Kolkman, A. S. Van Petersen, A. B. Huisman, Ernst J. Kuipers, R. H. Geelkerken Novel Role for Hydrogen Peroxide in Ach-lnduced Dilation of Human Intestinal Microvessels Ossama A. Hatoum, David D. Binion, Hiroto Miura, John J. Bosnjak, Mary F. Otterson, Gordon L. Telford, David D. Gutterman Gastric Ischemic Pain with Normal Mesenteric Vessels: A New Disease Entity? Report on Diagnosis, Treatment and Outcome in 14 Patients J. J. Kolkman, P. B. F. Mensink, A. B. Huisman, Ernst Kuipers, R. H. Geelkerken A Novel Role for Angiotensin II Type 1 Receptors in the Intestinal Microvascular Dysfunction Induced by Ischemia and Reperfusion Thomas Petnehazy, Karen Y. Stokes, D. Neff Granger I S1785 Ethanol Preconditioning Prevents Post-ischemic Leukocyte Adhesion in Both Gender Murine Small Intestine and Involves PKC-dependent Pathway Taiji Yamaguchi, Kazuhiro Kamada, Catherine Dayton, Toshikazu Yoshikawa, Ronald J. Korthuis Anti-Inflammatory Effect of Candesartan, a Angiotensin 2 Type 1 Receptor Blocker, on Ischemia/Reperfusion- Induced Intestinal Mucosal Injury in Rats Yutaka lsozaki, Norimasa Yoshida, Tomohisa Takagi, Kazuhiro Katada, Hiroki Manabe, Satoshi Kokura, Hiroshi Ichikawa, Yuji Naito, Toru Tanigawa, Takeshi Okanoue, Toshikazu Yoshikawa Magnesium Deficiency Alters Intestinal Response to Ischemia/Reperfusion Bradford J. Scanlan, Sunny K. Whiteman, Justin E. Elfrey, Blaine Tuft, Aiping Zhao, William B. Weglicki, Terez Shea- Donohue Angiotensin 1-7 Mediates Protective Action of Lisinopril in Ischemia/Reperfusion Injury of the Proximal Jejunum Ryszard Sendur, Jaroslaw Biemat, Rafal Obuchowicz, Michal Pawlik, Artur Dembinski, Wieslaw W. Pawlik Identification of Intestinal Ischemia Using Magnetic Vector Projection Analysis Jared A. Sims, Robert L. Palmer, L. Alan Bradshaw, William O. Richards Protective Effects of a Protease Inhibitor (Gabexate Mesilate) on Intestinal lschemia/reperfusion Injm-y in Rats Francesco Calcina, Carla Sternini. Pao/a Ghi:_-ardi F~,,T, Cattaruzza, Simona Bertoni. Vigilin Ballah~ni, Xl~lti~UnT21tn~i Impicciatore, Elisabetta Barocelli Ischemic Preconditioning Attenuates Ischemia/ Reperfusion-lnduced Mucosal Apoptosis via hnproving Mitochondrial Membrane Potential in Rat Small Intestine Masatoki Adachi, Bin Wu, Akifumi Ootani. P~vuicht I~xal:~ Takehiro Pujise, Se0i Tsunada. Kazuma FLtiimotn Catalase Is the Predominant Protective Mechanism Against H:O:-induced Barrier Dysfunction in Rat Colon Yolanda Adame-Navarrete, Jesus A. Fernandez Rq~lC,a. Julio M. Mayol AM-5:00 PM Hall F Sponsored by: Nutrition & Obesity OBESITY AND SATIERY Roux-en-Y Gastric Bypass in Rats Alters Hypothalamic $1786 Weight Regulation Through a Decrease in Circulating Ghrelin Levels Shishir K. Maithel, Nicholas Stylopoulos, David W. Rattner, Daniel B. Jones, Lee M. Kaplan Endoscopic Burden of Anastomotic Ulceration and $1787 Stricture After Roux-en-Y Gastric Bypass Brintha Krishnamoorthy, Timothy S. Kuwada, Ervin Denham, Kenric Muryama, Alexander P. Nagle, Thomas W. Powers, Peter J. Kahrilas, Jay B. Prystowsky, John E. Pandolfino Gastric Pacemaker Therapy for Weight Loss in Severely S1788 Obsese Patients Does Not Operate by the Mechanism of Gastric Emptying Claudia Knippig, Jochin Weigt, Stefanie Wolff, Sabine Westphal, Andreas Leodolter, Hans Lippert, Peter Malfertheiner Denotes DDW Poster of Distinction P-149

39 S U N D A Y MAY 16 $1789 $1790 S1791 $1792 $1793 S1794 S1795 S1796 $1797 $1798 S1799 $1800 $1801 A Prospective Evaluation of a New Intra-gastric Balloon for the Treatment of Obesity: A Two-center Experience Arnaldo J. Ganc, Aureo L. De Paula, Ricardo L. Ganc Gene Expression Profiles Associated with Obesity Sveta Nazarenko, Ancha Baranova, Hazem Elariny, Karen Schlauch, Abraham Younoszai, Shobha Gowder, Tariq Alsheddi, Francesco Goretta, Olivier Court, H. David Reines, Vikas Chandhoke, Zobair M. Younossi Failure to Diagnose Obesity and Screen for Fatty Liver Disease in Pediatric Practice Matthew R. Riley, William E. Berquist, Philip RosenthaI, Nathan M. Bass, Raphael B. Merriman Cutaneous Gastric Electrical Stimulation at Tachygastrial Frequency Induces Dyspeptic Symptoms and Delays Gastric Emptying in Healthy Humans Jing Wang, Jinsong Liu, Xiaohua Hou, J. D. Z. Chen Therapeutic Potential of Fundic Electrical Stimulation for Obesity: A Preliminary Clinical Study Jun Liu, Xiaohua Hou, J. D. Z. Chen Intraparenchymal Infusion of Brain Derived Neurotrophic Factor in the Dorsal Vagal Complex Induces Anorexia, Hypodipsia and Weight Loss in Rat Bruno Bariohay, Bruno Lebrun, Magali Hay, Emmanuel Moyse, Andre Jean Nutrient Drink Test Predicts Food Intake from a Standard Buffet Meal in Obesity Filippo Cremonini, Michael Camilleri, Jonathan Gonenne, Kari Baxter, Duane Burton POSTER SESSIONSmCOMBINED SCIENCE Protein Induced Satiety Is Not Altered by Fat in Healthy Human Subjects Sibylle Oesch, Lukas Degen, Christoph Beglinger A Novel Selective Human BRS-3 Agonist Induces CREB Phosphorylation and Transactivation Xiaoqun Qin, Sreenivas Garla, Xiangpmg Qu, Dongmei Xiao, David Coy, Horst C. Weber Effects of Diet and Weight Loss on Activity of Blood Mononuclear Cells in vitro and Chemiluminescence of Neutrophils in Women with Visceral Obesity Krystyna W. Zwirska-Korczala, Stanislaw J. Konturek, Tomasz Brzozowski, Zenon Czuba, Anna Sitkiewicz, Agnieszka Berdowska, Wojciech Krol Upper Abdominal Symptoms Are not Associated with Changes in Body Mass Index (BMI) Nicholas J. Talley, G. Richard Locke III, Cathy D. Schleck, Hiedi Treitline, Patrick H. Griffin, Alan R. Zinsmeister Obesity Increases Cost and Length of Stay Among Patients Undergoing Elective Surgical Procedures Alison G. Hoppin, Richard A. Wiklund, Lee Kaplan Loss of Gastrin Gene Expression Results in Insulin Resistance and Abdominal Obesity in Mutant Mice Stephanie L. Cobb, Michael J. Quast, Ligia M. Belalcazar, Jingna Wei, Gurpreet Singh, Pomila Singh P Denotes DDW Poster of Distinction

40 POSTER SESSIONS--BASIC SCIENCE BASIC SCIENCE AASLD Poster Session Authors are required to be present during the Poster Session from 12:00-2:00 pm. Those posters identified as DDW Posters of Distinction have received review scores that place them within the top 10% of all posters. We encourage you to make them a priority as you visit the poster session. AM-5:00 PM Hall F PORTAL HYPERTENSION: EXPERIMENTAL M905 M906 M907 M908 Increased Expression of Renal Neutral Endopeptidase (EC ) in Rats with CCL4-Induced Cirrhosis with Ascites: Acute Effects of Its Pharmacological Inhibition with i.v. Candoxatrilat Giovanni Sansoe, Manuela Aragno, Francesca Restivo, Giulio Mengozzi, Antonina Smedile, Giovanni Touscoz, Floriano Rosina, Oliviero Danni, Mario Rizzetto Decreased Expression of a 72-kDa Heat Shock Protein in Kidney of Biliary Cirrhotic Rats Ken-lchiro Mikami, Takashi Goto, Michiro Otaka, Kouichi Miura, Shigetoshi Ohshima, Kazuo Yoneyama, Daisuke Watanabe, Daisuke Segawa, Ei Kataoka, Tomomi Shibuya, Ryutaro Yoshino, Sumio Watanabe NCX-999, a NO-Releasing Derivative of UDCA, Modulates Hepatic Stellate Cells and Reduces Vasomotor Response to Nor-Epinefrine in Intact Rats Stefano Fiorucci, Elisabetta Antonelli, Anna Rita Di Lorenzo, Eleonora Distrutti, Monia Baldoni, Andrea Mencarelli, Antonio Morelli Selective COX-1 Inhibition Reduces Portal Vein Pressure in Portal Hypertensive Rats Tomohiko Akahoshi, Tetsuya Tanigawa, Andrzej S. Tarnawski, Shiun-Kwei Chiou, Makoto Hashizume, Yoshihiko Maehara, Michael K. Jones AM-5:00 PM Hall F Sponsored by: Esophageal, Gastric and Duodenal Disorders GASTRIC EPITHELIAL SIGNALING DURING HELICOBACTER INFECTION M909 8 M910 M911 The Polymorphism Interleukin-8-251A Is Associated with Enhanced Transcriptional Activity and a Progression of Gastric Atrophy in Helicobacter Pylori Infection Motoki Ohyauchi, Akira Imatani, Makoto Yonechi, Shuichi Ohara, Atsushi Masamune Jr., Tomoyuki Koike, Katsunori Iijima, Naoki Asano, Atsushi Miura, Tooru Shimosegawa H. pylori Regulates H,K-ATPase Expression at Spl and MZF 1-4 Response Elements in the o Subunit Promoter Adam Smolka, Charles E. Hammond lndomethacin Alters Helicobacter pylori CagA-Dependent Signalling in Gastric Epithelial Cells in vitro Martin W. James, Richard H. Argent, Christopher J. Hawkey, John C. Atherton FI.Pylori Colonization Downregulates the Sonic M912 Hedgehog (SHH) Gradient in the Stomach of Mongolian Gerbils Hidekazu Suzuki, Yuriko Minegishi, Takayuki Ota, Tatsuhiro Masaoka, Emi Takashima, Gijs R. van den Brink, Hiromasa Ishii Activation of the JAK-STAT Signaling Pathway by M913 Helicobacter Pylori CagA Protein in Gastric Epithelial Cells Wai K. Leung, Michael W. Y. Chan, Yoshio Yamaoka, Ka- Kui Chan, Joseph J. Y. Sung Inhibition of Proinflammatory Cytokine Expression by M914 Nf-kB (P65) Antisense Oligonucleotide in Helicobacter Pylori-lnfected Mice Sang Gyun Kim, Joo Sung Kim, Jung Mogg Kim, Hyun Chae Jung, In Sung Song Regulation of RANTES Promoter Activation in Gastric M915 Epithelial Cells Infected with Helicobacter pylori Takahiko Kudo, Hong Lu, Antonella Casola, Allan R. Brasier, David Y. Graham, Yoshio Yamaoka Interleukin-10 Suppresses Helicobacter pylori Induced M916 Interleukin-8 Secretion and Increases H. pylori Survival by Acting Directly on the Epithelial Cell Karen Robinson, John Atherton Helicobacter Pylari Regulates the Levels of Protein M917 Tyrosine Phosphatases 1B and 1D, in Addition to Altering Levels of Tyrosine Phosphorylation, within a Human Primary Antra/Cell Preparation and the Human Gastric Epithelial Cell Line, NCI-N87 Victoria S. Conlin, Jian Kang, Susan Curtis, Ying Zhao, Edwin Moore, Steven Pelech, Alison Buchan Geranylgeranylacetone Attenuates Expression of M918 Inflammatory Cytokines in Gastric Epithelial Cells During Exposure to Hyperosmotic Stress and/or H. Pylori Akinori Yanaka, Songhua Zhang, Masafumi Tauchi, Hideo Suzuki, Takeshi Shibahara, Hirofumi Matsui, Akira Nakahara, Naomi Tanaka Expression of Urokinase-Type Plasminogen Activator, M919 Its Receptor and Plasminogen Activator Inhibitor-1 in the Gastric Cancer Cells and Effect of Helicobacter Pylori Jun-lch Iwamoto, "fuji Mizokami, Kimiko Takahashi, Takeshi Matsuoka Long Term Chronic Helicobacter pylon Infection M920 Upregulates Gastric EGFR, c-met, ADAM 17 and COX-2 Expression in the Mongolian Gerbil Anthony H. T. Jeremy, M. Aboshkiwa, Michael F. Dixon, Philip A. Robinson, Jean E. Crabtree Ecabet Sodium Inhibits Helicobacter Pylori M921 Lipopolysaccharide-Induced Activation of NADPH Oxidase 1 and Apoptosis of Guinea Pig Gastric Mucosal Cells Kazuhito Rokutan, Kenji Kusumoto, Tsukasa Kawahara, Shigetada Teshima-Kondo, Yuki Kuwano, Kiyoshi Masuda Denotes DDW Poster of Distinction P- 151

41 POSTER SESSIONS--BASIC SCIENCE AM-5:00 PM Hall F Sponsored by: Gastrointestinal Oncology GROWTH FACTORS AND SIGNAL TRANSDUCTION EGFR is Upregulated in Human Colonic Aberrant Crypt M922 Eoci Greg Cohen, Gerry Boss, Piotr Obara, Alessandro Fichera, Nathaniel Little, John Hart, Marc Bissonnette M932 M933 Functional Correlation of Growth Suppression with Activin Treatment in Microsatellite Unstable, Activin Type 2 Receptor (ACVR2)-Restored Colorectal Cancer Cells Barbara Jung, Stayce Beck, Antonio Fiorino, Ryan T. Doctolero, E. J. Smith, Melanie Bocanegra, Betty L. Cabrera, John M. Carethers Osteopontin (OPN) is Differentially Activated by Two Low-Calcemic Analogs of la,25-dihydroxyvitamin D3 (VD3) but Inhibited by Tcf-4 Mella McCann, Mohamed E1-Tanani, Margaret Hoper, Gary Posner, Frederick C. Campbell a O N D A Y MAY 17 EGFR Antagonist Iressa Inhibits Receptor Activation, M923 Colonic Hyperproliferation and Aberrant Crypt Formation in the Rat Azoxymethane Model of Colon Cancer Sharad Khare, Nathaniel Little, Reba Mustafi, Greg Cohen, Sonia Cerda, Nirmita Kumar, Ramesh Wall, Maria Tretiakova, Loren Joseph, Yan Chun Li, Alessandro Fichera, Marc Bissonnette Deoxycholyltaurine (DCT)-Induced Proliferation of M924 H508 Colon Cancer Cells Is Mediated by Transactivation of Epidermal Growth Factor Receptors (EGFR) Kunrong Cheng, Jean-Pierre Raufman K-ras Can Inhibit GSK-3~ and Stimulate the Wnt M925 Signaling Pathway in Colon Cancer Jingnan Li, Yusuke Mizukami, Xiaobo Zhang, Won-Seok Jo, Daniel C. Chung Prostaglandin E2-EP3 Signaling Stimulates Angiogenesis M926 in Gastric Cancer via Induction of VEGF Expression Kazuhide Higuchk Toshio Watanabe, Harunori Fujita, Tetsuya Tanigawa, Takashi Takashima, Masaki Hamaguchi, Eiji Sasaki, Kazunari Tominaga, Yasuhiro Fujiwara, Tetsuo Arakawa ErbB Kinase and Heregnlin Signaling and Their Role on M927 VEGF Secretion in Colon Cancer Cells Masaoki Yonezawa, Ken Wada, Atsusi Tatuguchi, Tomonori Akamatsu, Katya Gudis, Shunji Fujimori, Choitsu Sakamoto Activin A Stimulates Vascular Endothelial Growth M928 Factor Gene Transcription in Human Hepatocellular Carcinoma Cells Karola Wagner, Michael Peters, Arne Schoh, Christoph Benckert, Bertram Wiedenmann, Stefan Rosewicz Competition Between Spl-Like Activators and M929 Repressors Determines the Cellular Gene Response to TGFbeta Anita Buck, Volker Ellenrieder, Kerstin Jungert, Heike Moennich, Aria Harth, Guido Adler, Thomas M. Cress PI3K/AKT Attenuates Growth Suppression by TGF~ Via M930 SMAD3 in TGFBR2-Restored HCTll6 Colon Cancer Cells Antonio Fiorino, Betty Cabrera, Stayce Beck, John M. Carethers M934 M935 M936 M937 M938 M939 M940 M941 M942 Peroxisome Proliferator-activated Receptor Expression and Activation in Normal Human Colonic Epithelial Cells and Tubular Adenomas Mads W. Matthiessen, Gitte Pedersen, Tatjana Albrektsen, Sven Adamsen, Jan Fleckner, Jorn Brynskov In vitro Use of PPARgamma Inhibitors Results in Nonapoptotic Mechanisms of Cell Death in Human Colon Cancer Cell Lines Katherine L. Schaefer, Svetlana Denevich, Kenny S. Yung, Lawrence J. Saubermann Sulindac Metabolites Induce Apoptosis in Colon Cancer Cells by Selectively Downregulating the MAP Kinase Arm of EGF Receptor Signaling Hanna M. Kraus, Pamela Rice, Dennis Ahnen, Heather Walczak The Matrix Melloproteinase Inhibitor Actinonin Blocks the Invasion of CC531 Tumor Cells cx vivo and Reduces Hepatic Metastasis in a Rat Liver Tumor Model in Vivo Christoph Isbert, Christoph T. Germer, Detlef Schuppan, Heinz J. Buhr, Joerg Ritz, Regina Fenski Ets Gene, PEA3 Cooperates with B-catenin-Lef-1 and c- jun in Regulation of Osteopontin Transcription Mohamed E1-Tanani, Angela Platt-Higgins, Philip Rudland, Frederick C. Campbell EGFR: A Potential Target of the Wnt/l~-Catenin Pathway in Liver Xinping Tan, Amanda Micsenyi, George K. Michalopoulos, Satdarshan S. Monga PKC-dependent Interleukin-8 Induction by Neurotensin in Human Colon Cancer Cell Lines Xiaofu Wang, Qingding Wang, Andy L. Chen, B. Mark Evers Constitutive Activation of MEK1 Signaling Transforms Rat Intestinal Epithelial Cells Koga Komatsu, Katkuri Sharada, Michiro Otaka, Sumio Watanabe, Raymond N. DuBois C-Terminal SRC Kinase (CSK) Acts as a Tumor Suppressor Gene in Colon Cancer (CRC) Cells Dhananjay Kunte, Ramesh Walk Jennifer Koetsier, A. Yu Kilimnik, I. G. Pyatkin, Y. A. Fedotov, M. N. Kostjukova, S. R. Strelnikova, Hemant Roy Analysis of TGF-[~ Signal Targets in Smad4-knocked M931 Down Pancreatic Cancer Cells Amarsanaa Jazag, Ijichi Hideaki, Imamura Takaaki, Kanai Fumihiko, Guleng Bayasi, Ohta Miki, Imamura Jun, Tanaka Yasuo, Tateishi Keisuke, Ikenoue Tsuneo, Kawakami Takayuki, Kawabe Takao, Miyagishi Makoto, Taira Kazunari, Omata Masao M943 M944 The Writ Signaling Inhibitor ICAT May Function as a Negative Feedback Regulator of Beta-catenin in Colorectal Carcinoma (CRC) Anke Reinacher-Schick, Stephan E. Baldus, Claus Michels, Irmgard Schwarte-Waldhoff, Wolff Schmiegel, Cara J. Gottardi Increased Expression of p53 Prevents Malignant Transformation of Normal Enterocytes (Iec18) with an Active Writ2 Pathway Meirav Rozenblat, Hadas Dvory4obol, Diana Kazanov, Ludmila Strict, Elisa Tiomny, Liora Madar-Shapiro, Nadir Arber P Denotes DDW Poster of Distinction

42 POSTER SESSIONSmBASIC SCIENCE M945 M946 M947 M948 Tethered Transforming Growth Factor Alpha (TGFo0 Is Expressed by A Variety of Colorectal Cancer Cell Lines and May Be Responsible For Up-Regulation of the Epidermal Growth Factor Receptor (EGFR) Arjun Takhar, Joseph Harris, Phil Clarke, Sue Watson JNK1 Up-Regulates the Expression of XIAP-Associated Factor 1 (XAF1) by a P53-Dependent Pathway in Gastrointestinal Cancer Jide Wang, Qing Gu, Harry H. X. Xia, ShuiPing Tu, Jun Zhong Peng, Yi Yang, Bing Zou, Marrie C. M. Lin, H. F. Kung, S. K. Lam, Benjamin C. Y. Wong RACK1 Regulates Mitogenic Signaling and G~/S Transition by Suppressing Src Kinase Activity Vidya Mamidipudi, Jian Zhang, Kelly Lee, Christine A. Cartwright Selective Induction of Apoptosis in Human Colon Cancer Cells with Active Wnt/[~-catenin Pathway Hadas Dvory-Sobol, Meirav Rozenblat, Diana Kazanov, Efrat Cohen-Noyman, Liora Madar-Shapiro, Aharon Hallak, Nadir Arber AM-5:00 PM Hall F Sponsored by: Growth, Development and Aging GI DEVELOPMENT M949 M950 M951 M952 M953 M954 M955 M956 M957 An L198P Substitution of the Cdx2 Abolishes Inhibitory Functions of Cdx2 on Cell Growth Trang B. Nguyen, Wei Xu, Erinn B. Rankin, EunRan Sub Intestinal Metaplasia of Gastric Mucosa Following Fusion with Intestine Does Not Involve Cdxl/Cdx2 Yasushi Fukushima, Keisuke Tateishi, Takashi Ishikawa, Toshihito Saitoh, Masao Omata Mechanisms Underlying Regulation of the Enterocyte Differentiation Marker Intestinal Alkaline Phosphatase Gene by Cdxl and Cdx2 Fuad Alkhoury, Moushumi Mozumder, Wenying Zhang, Premraj Pushpakaran, Elizabeth Fleming, Madhu S. Malo, Richard A. Hodin Cdxl or Cdx2 Expression in Human Colon Cancer Colo 205 Cells Induces Adherens, Desmosomal, and Tightjunction Proteins Toshihiko Ezaki, Rong J. Guo, John P. Lynch Expression of the Tight Junction Molecule Claudin-2 in the Human Intestine: A Complex Segment-specific Pattern Related to GATA-4 Expression Fabrice Escaffit, Francois Boudreau, Jean-Francois Beaulieu Cooperation Between GATA4 and TGF-beta Signaling Regulates Intestinal Epithelial Cell Specific Promoters Narasimhaswamy S. Belaguli, Helen Lu, David H. Berger Spatial-specific Activation of NF-KB and AP-1 and Induction of NOS-2 and HO-1 Expression in the Intestinal Crypt-villus Axis Induced by LPS in Rats Kwo-Yih Yeh, Mary Yeh, D. Nell Granger, Jonathan Glass Interaction Between Two Kruppel-Like Transcription Factors in Regulation of Intestinal Gene Expression Moushurni Mozumder, Madhu S. Malo, Premraj Pushpakaran, Fuad Alkhoury, Elizabeth Fleming, Long- Chuan Bai, Juanita Merchant, Richard A. Hodin Regulation of Intestinal Cell Differentiation by the Transcription Factor NFAT Qingding Wang, Xiaofu Wang, B. Mark Evers M958 M959 M960 M961 8 M962 M963 M964 8 M965 M966 M967 M968 M969 M970 M971 M972 M973 Serum Response Factor Regulates the Expression of Pancreas Duodenum Homeobox-1 Gene Narasimhaswamy S. Belaguli, Helen Lu, Michael S. Parmacek, Robert J. Schwartz, David H. Berger Histone Deacetylase 3 Inhibits the Function of Enterocyte Transcription Factors Fuad Alkhoury, Madhu S. Malo, Moushumi Mozumder, Premraj Pushpakaran, Elizabeth Fleming, Richard A. Hodin Expression of Specific Focal Adhesion Kinase (FAK) Phospho-Forms During Intestinal Development Abdul H. Khan, Robert Carroll, Richard V. Benya TGF-~I Induces Intestinal Myofibroblast Differentiation and Has an Ambivalent Effect on Cell Migration Sandra N. Leeb, Daniela Vogl, Werner Falk, Juergen Schoelmerich, Gerhard Rogler Role of ELF- a [3-Spectrin and Smad4 in TGF-~ Signaling and Digestive Tract Tumors Varalakshmi Katuri, Yi Tang, Bibhuti Mishra, Lopa Mishra Notch Expression in Adult Pancreas and Its Alteration in Streptozotocin-lnduced Diabetes in Rats Yasutada Akiba, Ken-Ichi Katsube, Masahiko Nakamura, Hiromasa Ishii Pancreatic Regeneration After Partial Pancreatectomy is Dependent on PI3K/Akt Activation Hiroaki Watanabe, Hiroshi Saito, Junji Ueda, B. Mark Evers Roles of CTPL/Sfxn3 and Sfxn Family Members in the Differentiation and Regeneration of Pancreatic Islet Yukako Yoshikumi, Hirosato Mashima, Namiki Ueda, Hideki Ohno, Junko Suzuki, Masao Omata Cathepsin L Regulates Intestinal Epithelial Cell Differentiation Carine Lussier, Marc-Emile Plourde, Etienne Lemieux, EunRan Suh, Francois Boudreau Increased Intestinal and Hepatic Growth and Altered Spermatogenesis in Epimorphin Null Mice Yuan Wang, Yi Lu, Hristo Iordanov, Lihua Wang, Elzbieta A. Swietlicki, Marc S. Levin, Deborah C. Rubin Neurogenin3 Expression in Gastrointestinal Progenitor Cells Does Not Commit Cells to Adopt an Endocrine Cell Fate Susan E. Schonhoff, Maryann Giel, Andrew B. Leiter Developmental Expression of mrnas Encoding Proteins Involved in RNA Translocation Shabana Islam, Robert K. Montgomery, Richard J. Grand Fungal-Bacterial Consorts in the Development of an lmmunoregulatory B Cell Subset David A. Ziring, Bo Wei, Jonathan Braun, James Borncman IL-7 Administration Alters the Function and Phenotype of Intestinal Intraepithelial Lymphocytes in Mice Hua Yang, Ariel U. Spencer, Daniel H. Teitelbaum Macrophage Small Talk with Memory T-Cells at the Epithelial Fence Martin Hausmann, Frauke Bataille, Tanja Spoettl, Katja Schreiter, Werner Falk, Juergen Schoelmerich, Hans Herfarth, Gerhard Rogler Enhanced Bile Acid-induced Hepatic Oxidative Injury in the Obese Zucker Rat: An in viva Model of "Steatocholestasis" Ronald J. Sokol, Gregory Kobak, Michael Devereaux, Rolf Dahl, Eric Gumpricht Denotes DDW Poster of Distinction P-153

43 POSTER SESSIONSmBASIC SCIENCE M974 M975 M976 Total Parenteral Nutrition Prior to Oral Feeding Predispose to Spontaneous Development of NEC in Premature Piglets Charlotte R. Bjornvad, Thomas T. Nielsen, Bent B. Jensen, Soren K Jensen, Per T. Sangild Liver Growth Hormone Resistance Precedes Growth Failure in Experimental Colitis Lee Denson, Jiman He, Lisa DiFedele, Erin Bonkowski, Matthew Held Glucocorticoid Treatment Prior to Preterm Birth: Effects on Intestinal Maturation in Fetal Lambs and Baboons Per T. Sangild, Peter W. Nathanielsz, Kathie A. Berghorn, Abigail L. Fowden M984 M985 NogoA-Immunoreactivity is Extensively Expressed in the Human Enteric Nervous System and in Some Enteroendocrine (EE) Cells Roxane Peddle, Inger-Sofie Selmer, Adebayo Adeeko, Stephen E. Moore, Robert H. Riddell, Ronald H. Stead Expression of Notch Pathway Components in Adult Rat Stomach Hiroshi Nagata, Yasutada Akiba, Hidekazu Suzuki, Hiromasa Ishii AM-5:00 PM Hall F M O N D A Y MAY 17 AM-5:00 PM Hall F Modal Convention Center Sponsored by: Hormones, Transmitters, Growth Factors and Their Receptors HORMONES/RECEPTORS: GI CELL GROWTH/ DIFFERENTIATION/APOPTOSIS M977 M978 M979 M980 M981 M982 M983 Ephrin-A1 Mediated Eph A2 Stimulation at Cell-cell Contacts Induces 'Inside-out' FAK Phosphorylation Modifying Survival Signaling and Anchorage Dependence in Primary Normal and Neoplastic Human Intestinal Epithelial Cells (IEC) Claudia Hofmann, Monika Artinger, Bettina Federhofer, Thomas Vogt, Gerhard Rogler, Juergen Schoelmerich, Johannes Grossmann Progastrin Stimulates Murine Colonic Epithelial Mitosis After DNA Damage in the Absence of Murine Amidated Gastrin Penelope D. Ottewell, Andrea Varro, Alastair J. M. Watson, Rod Dimaline, Graham J. Dockray, D. M. Pritchard Leptin Prevents Sodium Butyrate-Induced Apoptosis in Human Colon Cancer HT-29 Cells via NFKAPPA-B Signalling Patricia Rouet-Benzineb, Thomas Aparicio, Sandra Guilmeau, Cecile Pouzet, Veronique Descatoire, Marion Buyse, Andre Bado Neuromedin B (NMB) and its Receptor (NMBR) are Mitogens in both Normal and Malignant Epithelial Cells Lining the Colon Damien Matusiak, Peter Coward, Sarah Glover, Anne Chai, Rajkumar Nathaniel, Jianxin Yang, Kristina Matkowskyj, Richard V. Benya Gastric Cell Apoptosis Induced by Gastrin Stimulation Is Mediated by CCK-B/Gastrin Receptors and Histamine- 2 Receptors Guanglin Cui, Shigeo Takaishi, Wandong Ai, Jane E. Carlson, Dana M. Frederick, Timothy C. Wang TRAIL Receptor Expression in Hereditary and Sporadic Colorectal Tumors as Targets for Apoptosis Induction and the Role of BAX Mutations as an Evading Mechanism Jan Koomstra, Mathilde Jalving, Fleur Rijcken, Jantine Westra, Nynke Zwart, Harry Hollema, Elisabeth de Vries, Robert Hofstra, Jan Kleibeuker, Steven de Jong Effects of Microgravity on Caco-2 Cells: Differentiation Fast-Fowarded Rebecca K. Anderson, Sarah Glover, Jessica A. Cobb, Roger Tran-Son-Tay, Richard V. Benya Sponsored by: Hormones, Transmitters, Growth Factors and Their Receptors HORMONES/TRANSMITTERS/RECEPTORS: GI MOTILITY Activation of Proteinase-Activated Receptor 2 Prevents M986 Gastrointestinal Transit Delay Induced by Ischemia/ Reperfusion in Rats Fiore Cattaruzza, Francesco Calcina, Yat Tang, Nathalie Vergnolle, Elisabetta Barocelli, Mariannina Impicciatore, Catia Sternini CRF Receptor l in the Brain Plays a Role in M987 Postoperative Ileus in Rats Andrew Luckey, Lixin Wang, Mulugata Million, Jozsef Czimmer, Yvette F. Tache Differential Determinants for Motilin Receptor M988 Activation by Peptide and Non-peptidyl Ligands Bunzo Matsuura, Maoqing Dong, Laurence J. Miller, Tomoyuki Yokota, Hidetaka Matsui, Morikazu Onji Differential Role of Nitric Oxide Synthase Isoforms on M989 Peristalsis in the Mouse Proximal Colon Abdelrazzag A. El-Majdoub, Robert J. Naylor, Bishwa R. Tuladhar Characterization of Guinea Pig Native and Recombinant M990 5-HT4 Receptors Ross G. Vickery, Ngoc A. Mai, M. T. Pulido-Rios, Mick D. O'Keefe, Jacqueline A. M. Smith, Patrick P. A. Humphrey Distinctive Signaling by Cannabinoid CB1 Receptors in M991 Smooth Muscle Cells: Absence of G~/-Dependent Activation of PLC-~ Sunila Mahavadi, Huiping Zhou, Kamam S. Murthy Purinergic Inhibitory Neuromuscular Transmission M992 Mediated by the P2Y~ Receptor in Guinea-Pig Small Intestine Guo-Du Wang, Hong-Zhen Hu, Xi-Yu Wang, Na Gao, Sumei Liu, Xiucai Fang, Yun Xia, Jackie D. Wood Functional Characterization of Neurokinin Type-1 M993 Receptors in the Ascending and Sigmoid Human Colon Michel Neunlist, Tsvetelina Oreshkova, Stanislas Bruley des Varannes, Christian Hamel, Jean-Paul Galmiche, Eckhard Weber Elevation of Intracellular Cyclic AMP Levels Contributes M994 to the Excitability of Myenteric AH/Dogiel Type II and S/Dogiel Type I Neurons with Polarized Projections Zhixiong Chen, Jorge E. Guzman, Jun Ge Yu, Iveta Grants, Helen J. Cooke, Fievos L. Christofi Tegaserod is a Potent 5-HT2~ Antagonist In Vitro and In M995 Vivo David T. Beattie, Scott R. Armstrong, Patrick P. A. Humphrey, Daniel Marquess, M. T. Pulidos-Rios, Jacqueline A. M. Smith P-IS4 8 Denotes DDW Poster of Distinction

44 r POSTER SESSIONS~BASIC SCIENCE M996 M997 M998 M999 M1000 M1001 M1002 M1003 M1004 M1005 M1006 M1007 M1008 M1009 Variability in the Detection of 5HT-Immunoreactive (IR) Enterochromaffin (EC) and Mast Cells (MC) in the Gastrointestinal Tract Roxane Peddle, David Vondracek, Inger-Sofie Selmer, Gareth Hicks, Robert H. Riddell, Ronald H. Stead Tachyphylaxis Assays for Motilin Agonist Drug Development Christopher W. Carreras, Mark Claypool, Daniel V. Santi, Jan A. J. Schuurkes, Theo L. Peeters, Robert G. Johnson Jr. Enteric Delta Opioid Receptors Are Key Components in Neuromuscular, Secretomotor and Viscerofugal Signaling Pathways Paul R. Wade, Jeffrey M. Palmer, Paul Saunders, Nathaniel Wallace, Craig Schneider, David Grundy, Ronald H. Stead, Pamela J. Hornby Homing in on ATP's Role in 5-Hydroxytryptamine Release in Mechanosensitive Carcinoid BON Cells Jianjing Xue, Fievos L. Christofi, Jacqueline E. Wunderlich, Y.-Z. Wang, Yong-Cheol Jeon, Helen J. Cooke Endothelin Receptors in Lower Esophageal Sphincter Circular Smooth Muscle Shih-Che Huang Leptin Delays Gastric Emptying Rate in Rats: Role of Vagal Afferent Fibers and CCK-1 Receptors Baris Cakir, Ozgur Kasimay, Ersin Devseren, Berrak C. Yegen Expression and Effects of CRF Receptors in the Rat Small Intestine Christophe Porcher, Aurelie Juhem, Andre Pemnequin, Valerie Sinniger, Bruno Bonaz The NK~ Receptor Antagonist Talnetant (SB ) Modulates Peristalsis Induced by Supra-optimal Distension Pressure in the Guinea Pig Isolated Ileum Bishwa R. Tuladhar, Emtiaz Aziz, Gareth J. Sanger A Novel in vivo Model of 5-HT~ Receptor-mediated Esophageal Relaxation in the Anesthetized Rat Scott R. Armstrong, Julia L. McCullough, Gleumar P. Obedencio, Daniel Marquess, Patrick P. A. Humphrey, David T. Beattie Involvement of Endogenous Opiates in the Inhibitory Effect of Clonidine on Peristalsis in the Mouse Isolated Colon Bishwa R. Tuladhar, Emtiaz Aziz, Gareth J. Sanger Exogenous Adenosine Increases Sphincter of Oddi Motility, Acting via Cholinergic Motor Neurons Charmaine M. Woods, James Toouli, Gino T. P. Saccone Lysophosphatidic Acid (LPA) Interacts with LPA3 Receptors to Activate Selectively GOLq and Induce Initial and Sustained MLC20 Phosphorylation and Contraction Huiping Zhou, Jiean Huang, Karnam S. Murthy Acetylcholine-Induced Phosphorylation of Tropomyosin at Smooth Muscle Specific PKC Sites in Colonic Smooth Muscle Cells Sita Somara, Khalil N. Bitar Activation of the GHS-Receptor Accelerates Gastric Emptying in Dogs Benoit Moreaux, Joke Van den Berg, Leen Thielemans, Ann Meulemans, Bernard Coulie AM-5:00 PM Hall F Sponsored by: Immunology, Microbiology & Inflammatory Bowel Disorders EPITHELIAL CELL: IMMUNE CELL INTERACTIONS Carcinoembryonic Antigen (CEA) Downregulates IL-12 M1010 in Macrophages Mee S. Park, Lloyd Mayer The Role of Setectins in the Intestinal Epithelial M1011 Migration of HL-60 Differentiated Eosinophils Sonia Micbail, Frank Abernathy CDld and the CEA Subfamily Member, gp180, Activate M1012 a Diverse Subset of CD8 + Cells Ling Shao, Adam R. Jacobs, Valerte V. Johnson, Lloyd Mayer COX-2 Inhibition Increases Chemokine Production and M1013 Splenocyte Proliferation in a Model of Colorectal Cancer Alice J. Walmesley, Stephen E. Christmas, Alastair J. M. Watson AM-5:00 PM Hall F Sponsored by: Immunology, Microbiology & Inflammatory Bowel Disorders IBD: ANIMAL MODELS, PRE-CLINICAL TREATMENT AND NOVEL THERAPIES M M1015 MlO16 M1017 M1018 M1019 Therapeutic Efficacy of Blocking Smad7 in TNBSinduced Colitis Monica Boirivant, Francesco Pallone, Ivan Monteleone, Claudia di Giacinto, Mariarosaria Marinaro, Thomas T. Macdonald, Giovanni Monteleone Specific Regulation of Interferon-Gamma by CEACAM1 Through the Specific Inhibition of Mitogen Activated Protein Kinase and T-BET....~ Hideki Iijima, Markus Neurath, Daohang Chen. Iaka<tni Nagaishi, Christoph Becket, Kathr}qn V Hohnes, Rkhard _'- :::i:j: :i:i]}_~..~ Blumberg : : : : ::)~ In situ Demonstration of Monocyte Migration in Spontaneous Ileitis of SAMP1/YIT Mice -Attenuating :::: :i :7:~ Effects of Anti-PSGL-1 Antibody :~ : _ ~ Hisayuki Matsunaga, Yoshikazu Tsuzuki, Kqji M:tlsLtz.tl,.t. :~:~ Takuya Inoue, Ryota Hokari, Yoslnikw,~ Okacl: :\tsk>hi 3~ Kawaguchi, qhigeaki Nagao, Kazuro Itoln qatoshi... Matsumoto, Soichiro Miura : ::~ The Effect of ~-Galactosylceramide on Chronic!~ Enterocolitis in IL-10 Deficient Mice ~ Manabu Shiraki, Hiroyuki Ailnara, Mitsunori No<uchi Motoji Oki, Seiichi Takahashi, Kazuma -takahashi, Yoshitaka Kinouchi, Tooru Shimosegawa A Critical Role for the The Lymphotoxin Beta Receptor in Murine Citrohacter Rodentium-lnduced Colitis Thomas W. Spahn, Christian Maaser, Lars Eckmann, Jan Heidemann, Hermann Herbst, Wolfram Domschke, Torsten Kucharzik Intestinal Helminths Induce Lamina Propria T cell ILl0, Which Inhibits Mucosal IFN~/Production David E. Elliott, Tommy Setiawan, Ahmed Metwali, Ying Wang, Arthur Blum, Joseph F. Urban Jr., Joel V. Weinstock Denotes DDW Poster of Distinction P-155

45 POSTER SESSIONS--BASIC SCIENCE M O N D A Y MAY 17 M1020 M1021 M1022 M1023 M1024 M1025 M1026 M1027 M1028 M1029 M1030 M1031 M1032 M1033 Inhibition of Histone Deacetylases Exerts a Strong Antiinflammatory Potency in Experimental Colitis Britta Siegmund, Arvind Batra, Inka Fedke, Flavio Leoni, Giamila Fantuzzi, Martin Zeitz, Paolo Mascagni, Charles A. Dinarello Glucocerebroside Treatment Ameliorates Experimental Colitis: A New Immune-Modulatory Tool Maya Margalit, Ruslana Alper, Barbara E. Thalenfeld, Dean L. Engelhardt, Elazar Rabbani, Yaron llan Complex Effects of Ppargamma Activation on Crohn's Disease in Mice Kazuhiko Sugawara, Brian K. Stevens, Sharon B. Hoang, Christopher A. Moskaluk, Fabio Cominelli, Marcia J. McDuffie The Vitamin D3 and Dexamethasone Induced Regulatory T Cell Does Not Correlate to the Expression of Foxp3 Makoto Naganuma, Kevin G.E. Scott, Peter B. Ernst 2'-Deoxycoformycin Reduces Inflammation and Attenuates Expansion Within Lymphoid Inductive Sites in Murine IL-IO-/- Colitis Jeffrey B. Brown, Terrence A. Barrett The A3 Adenosine Receptor Agonist IB-MECA Is Beneficial in TNBS-Colitis Jorge E. Guzman, Najma H. Javed, Arturo J. Cardounel, Karl Kornacker, Jun Ge Yu, Iveta Grants, Helen J. Cooke, Fievos L, Christofi Effects of Antisense Oligonucleotides to the p65 Subunit of NF-kappa B on Expression of Pro-Inflammatory Cytokines in Lamina Propria Mononuclear Cells from Patients With Ulcerative Colitis Hua Tian Garl, Qin Ouyang, You Qin Chen Efficacy of CXCR2 Antagonist (SB265610) in Mouse Dextran Sodium Sulfate Model of Colitis Jong H. Nam, Nandhakumar Kanagarajan, Pouria Kashkouli, Zaid Alnoah, Sreekant Murthy Growth Hormone Reduces the Severity of Fibrosis Associated with Chronic Intestinal Inflammation Arianne L. Theiss, C. Randall Fuller, Bo Liu, R. Balfour Sartor, Pauline K. Lund Antibody Eosinophil Cationic Protein Treatment Inhibits Dextran Sulfate Sodium-Induced Colitis In Rats Kazuko Shichijo, Kazuya Makiyama, Chun-Yang Wen, Mutsumi Matsuu, Toshiyuki Nakayama, Masahiro Nakashima, Ichiro Sekine Anti-inflammatory Properties of Simvastatin and Atorvastatin in the Dextran Sulfate Sodium (DSS) Mouse Model of Colitis Jong H. Nam, Zaid Alnoah, Sreekant Murthy Cure of Colitis by CD4 + CD25 + Regulatory T Cells Christian Mottet, Holm H. Uhlig, Fiona Powrie Involvement of Nitric Oxide and Cyclooxygenase Products in the Ameloration of Ulcerative Colitis by Peroxisome Proliferator-Activated Receptor-Gamma (PPAR~/) in Rats Slawomir Kwiecien, Tomasz M. Brzozowski, Malgorzata Zwolinska-Wcislo, Peter C. Konturek, Robert Pajdo, Starlislaw J. Konmrek, Agata Machowska, Jozef Bogdal, Wieslaw W. Pawlik Severe Experimental Colitis in Apolipoprotein A-IV Knockout Mice Can Be Prevented with Recombinant Human Apolipoprotein A-IV treatment Thorsten Vowinkel, Theodore J. Kalogeris, Christian F. Krieglsteirl, Mijiki Mori, Richard H. Tumage, Patrick Tso, D. Neff Granger M1034 M1035 M1036 M1037 M1038 M1039 M1040 M1041 M1042 M1043 M1044 M1045 Probiotic Performance in IBD Is Not Uniform: A Multi- Strain Comparison in the Lymphocyte Transfer Model of Enterocolitis Kevirl Duke, Sharon Murphy, Myles Smith, Mary A. O'Donovan, Barry Kiely, John K. Collins, Liam O'Mahony, Fergus Sharlaharl Treatment of Acute Colitis of Mice by Hepatocyte Growth Factor Gene Transfer to the Liver via Tail Vein Yusuke Kawauchi, Kenji Suzuki, Takayasu Hanawa, Hiroyuki Yoneyama, Hiroki Maruyama, Gi Dong Han, Hiroshi Kawachi, Fujio Shimizu, Jun-Ichi Miyazaki, Hitoshi Asakura, Yutaka Aoyagi Amelioration of Acute Colitis of Mice by Enema of Anti- Inter feron-lnducible-protein 10-Antibody Kenji Suzuki, Yusuke Kawauchi, Yasuyuki Baba, Hiroyuki Yoneyama, Gi Dong Han, Hiroshi Kawachi, Shosaku Narumi, Fujio Shimizu, Hitoshi Asakura, Yutaka Aoyagi Synergistic Effects of Systemic Trefoil Factor Family 1 and Epidermal Growth Factor in a Rat Model of Colitis Anthony J. FitzGerald, M. Pu, Tania Marchbank, Bruce R. Westley, Felicity E. B. May, Joe Boyle, Masoud Yadollahi- Farsani, Subrata Ghosh, Raymond J. Playford Rectal Probiotic Enemas Induce Colonic Mucin Expression with Reduction of DSS-induced Colitis in Rats David R. Mack, Diya Adam, Siv Ahrne, Goran Molin, Bengt Jeppsson lmmuno-modulating Effect of Filamentous Hemagglutinine A of Bordetella Pertussis in Experimental Colitis Henri Braat, Inge Huibregtse, Peter Mc Guirk, Anje te Velde, Daan Hommes, Kingston Mills, Sander van Devemer Thioredoxin-1 Is a Novel Therapeutic Molecule for Inflammatory Bowel Disease Hiroyuki Tamaki, Akiyoshi Nishio, Satoko Inoue, Keiichi Kiriya, Hiroshi Kitamura, Hazuki Yoshizawa, Shinya Ohashi, Toshiro Fukui, Minoru Matsuura, Kimio Kawasaki, Hiroshi Nakase, Hajime Nakamura, Kazuichi Okazaki, Junji Yodoi, Tsutomu Thiba A Novel Anti-Oxidant, Terathiomorybdate, Attenuates Disease Activity in Experimental Colitis Makoto Sasaki, Takashi Job, Hiromi Kataoka, Satoshi Tanida, Keisuke ltoh, Tadayuki Oshima, Yutaka Kondo, Naotaka Ogasawara, Paul Jordan, J. Steven Alexander, Makoto Itoh Inducible NO Synthase Elaborates NO That Tonically Suppresses Contractility in Experimental Colitis in the Rat Sofie Lundberg, Per M. Hellstrom Oral Treatment with a Botanical Extract (Hypoxoside) Prevents Bacterial-Induced Colitis Michael J. Wannemuehler, Albert E. Jergens, Jesse M. Hostetter, Abigail Lozano, Zhiping Liu, Andrea Dora OPC-6535, a Novel Oral Thiazole Compound, Suppresses Colonic Damage in a Rat Model of TNBSinduced Colitis Hisashi Nagamoto, Takashi Maeda, Jun-Pei Haruta, Goro Miyakoda, Kazuo Sekiguchi, Toshihiro Osaka, Takako Nakashima, Mikio Kikuchi OPC-6535 Suppresses Symptoms and Colonic Damage in a Rat Model of DSS-induced Chronic Colitis Hisashi Nagamoto, Takashi Maeda, Jun-Pei Haruta, Goro Miyakoda, Toyoki Mori, Michiaki Tominaga P-]56 8 Denotes DDW Poster of Distinction

46 r Mt046 M1047 M1048 M1049 M1050 M1051 M1052 M1053 M1054 M1055 M1056 M1057 M1058 M1059 POSTER SESSIONSmBASIC A Small Molecule CCR5 Antagonist, TAK-779 Exacerbates Trinitrobenzene Sulfonic Acid (TNBS)- M1060 Induced Colitis Jugoh Itoh, Hidezumi Kikuchi, Masanori Tanaka, Shinsaku Fukuda, Akihiro Munakata Non-Pathogenic Escherichia Coli Prevents Acute and Chronic Colitis in Mice M1061 Nobuhiko Kamada, Nagamu Inoue, Takaya Yamada, Tatsuo Suzuki, [(young Su Hong, Hiromasa Ishii, Toshifumi Hibi E-Metanicotine Hemigalactarate (TC ) Inhibits IL-8 Production in Cells of the Inflamed Mucosa Tanja N. Spoettl, Christine Petzel, Hans Herfarth, Juergen Schoelmerich, Roland Greinwald, Gregory J. Gatto, Merouane Bencherif, Gerhard Rogler Bromelain Treatment of Inflammatory Bowel Disease Laura P. Hale, Marcia R. Gottfried, Jane E. Onken Halfsynthetic Boswellic Acids Attenuate Intestinal Inflammation in Experimental Colitis Christoph Anthoni, Emile J. M. Rijcken Jr., Rudolf Mennigen, Mike G. Laukoetter, Sarah A. Mueller, Johann M1062 Jauch, Norbert Senninger, Christian F. Krieglstein ~]] Stable Gastric Pentadecapeptide BPC 157 Studied for Inflammatory Bowel Disease (PLDll6, PL14736, Pliva) Induces Nitric Oxide Synthesis Branko Turkovic, Predrag Sikiric, Sven Seiwerth, Stjepan Mise, Tomislav Anic, Marijan Petek, Rudolf Rucman Normalizing Effects of Curcumin (Diferulolylmethane) on Colonic Gene Expression in TNBS Colitis. Pawel R. Kiela, Anna J. Midura, Fayez K. Ghishan I O M1063 U O Comparitive In Vitro Effects of Azo-Containing 5-ASA Pro-Drugs in Rabbit Distal Ileum Indicates All Induce Secretion M1064 Keri A. Kles, Stephan Vavricka, Mark W. Musch, Stephen ~a~ B. Hanauer, Eugene B. Chang Amelioration of Indomethacin-lnduced Small Intestinal Injury in Rats by Membrane-Anchored Phospholipase M1065 A2 Inhibitor Moshe Ligumsky, Meron Krimsky, Larissa Aptekar, Shaul Yedgar Artificial Cells Containing Thalidomide as an M1066 Alternative Oral Therapy Method for Crohn's Disease Terrence Metz, Devendra Amre, Mitchell Jones, Hongmei Chen, Wei Ouyang, Tasima Haque, Christopher Martoni, Satya Prakash Heat Shock Protein 70 Induced by M1067 Geranylgeranylacetone Protects Against Dextran Sulfate Sodium Colitis in Mice Tatsuya Ohkawara, Hiroshi Takeda, Kanji Kato, Kencho Miyashita, Shigeru Furukawa, Toshirou Sugiyama, Jun M1068 Nishihira, Masahiro Asaka Prophylactic Treatment with Losartan Reduces the Incidence of Fibrosis in Experimental Colitis by Reduction of TGF-[~I Dov Wengrower, Isa Metanes, Giuliana Zaninnelli, Mark Pines, Eran Goldin Bupropion Lowers Tumor Necrosis Factor-alpha in vivo, M1069 and Blunts Stimulated Lymphoproliferation Eric L. Altschuler, Milena B. P. Soares, Ricardo Ribeiro-dos- Santos, Danielle Brustolim, Richard E. Kast Gliotoxin Ameliorates TNBS-induced Colitis in Mice Through Down-modulation of NF-KB Activation, TNF-oL M1070 and IL-113 Expressions, and Up-regulation of Heme Oxygenase-1 Sang-Wook Kim, Geom Seok Seo, Kyoung Suk Kim, Yong Sung Kim, Young Woo Sohn, Joo Jin Yeom, Tae Hyeon Kim, Suck Chei Choi, Yong-Ho Nah, Jay Min Oh SCIENCE Subcutaneous Injection of Anti-IgE Antibody Inhibits Dextran Sulfate Sodium-lnduced Colitis in Mice Ok-Hwa Kang, Yeon-A. Choi, Yong Sung Kim, Joo Jin Yeom, Kyo Sang Yoo, Tae Hyeon Kim, Suck Chei Choi, Yong-Ho Nah, Young-Mi Lee Antioxidant Therapy Plus Mesalamine Accelerates Mucosal Healing in a Rodent Model of Colitis Ali A. Siddiqui, Hanumantha R. Ancha, Angela Ward, Muhammad K. Hasan, Dustin Tedesco, Stanley Lightfoot, Richard F. Harry AM-5:00 PM Hall F Sponsored by: Immunology, Microbiology & Inflammatory Bowel Disorders MICROBIAL-INDUCED INFLAMMATION AND IMMUNITY Blood Group B Specific Glycoconjugates Are Necessary for Invasion by Salmonella Typhimurium in Human Intestinal Epithelium Meredith Hass, Jae Sung Ko, Luke Scheidler, W. Allan Walker, N. Nanda Nanthakumar MHC Class ii Intestinal Myofibroblasts as Accessory Cells for Staphylococcal Enterotoxin-mediated T-cell Activation and Cytokine Secretion Irina V. Pinchuk, Carlos A. Barrera, Jamal I. Saada, David A. Bland, Giovanni Suarez, Ellen Beswick, Patrick A. Adegboyega, Randy C. Mifflin, Don W. Powell, Victor E. Reyes Oral Tolerance Is Intact in Germ-Free Mice Despite the Lack of Enteric Bacterial Colonization Kristen L. W. Walton, R. Balfour Sartor, Nancy C. Fisher Dendritic Cells Mediate Helicobacter PylorMnduced Chronic Gastritis John Y. Kao, Sivaprakash Rathinavelu, Yana Zavros, Long- Chuan Bai, Edwin Labut, Juanita L. Merchant Intestinal Helminth Infection Impairs Host Resistance and Enhances Colonic Pathology During Concurrent Citrobacter Rodentium Infection in Mice Chien-Chang Chen, Steve Louie, Weishu Zhu, Beth McCormick, W. Allan Walker, Hal Ning Shi C. Rodentium lifa/efal Is Essential for Colonic Hyperplasia and Inflammation in Mice Ifor R. Williams, Melanie Sherman, Daniel Kalman, Jan- Michael A. Klapproth Acute HIV Infection Is Characterized by a Preferential Depletion of CD4 + T Cells from Effector Sites in the Colon Saurabh Mehandru, Michael A. Poles, Klara Tenner-Racz. Paul Racz, Amir Horowitz, Christine M. Hogan, Sandhya Vasan, Arlene Hurley, Sarah Schlesinger, David Ho. Martin Markowitz Listeria Monocytogenes Triggers the Release of Interleukin-18 from Intestinal Epithelial Cells Klaus E. Schlottmann, Stefan Kiessling, Sybilla Korbel, Josef Schroeder, Wemer Goebel, Juergen Schoelmerich, Gerhard Rogler Microfloral Patterns in Pouchitis: A Novel Technique of Bacterial Fingerprinting Srinadh Komanduri, Pat Gillevet, Marc Brand, Ted Sadarides, Ali Keshavarzian Denotes DDW Poster of Distinction P-157

47 POSTER SESSIONS--BASIC SCIENCE M1071 Selective Expansion of Colitogenic Commensal Bacterial Species in SPF IL-10-/- Mice Julia Tsang, P, honda Brown, Gary Andersen, Torn Schmidt, Gerald Tannock, R. Balfour Sartor, Ken Wilson M1084 Distinct Host Pro-inflammatory Responses to Helicobacter hepaticus Infection by Intestinal Epithelial and Immune Cells Ming L. Chen, David B. Schauer M1072 Disruption of Tight Junctions and Loss of Epithelial Barrier Function by Helicobacter pylori in vivo and in vitro Are Strain-Dependent and Require Bacterial Adhesion Jason Fedwick, Jonathon Meddings, Andre Buret M1085 Induction of Expression of KLRG1 on NKT Cells and Conventional CD4 + and CD8oL + T Cells in Non- Lymphoid Tissues After Oral Listeria monocytogenes Infection Victor Arrunategui-Correa, Hyun Sil Kim M1073 Dual-Association of Gnotobiotic IL-10 Deficient (4-) Mice With Two Non-Pathogenic Commensal Bacterial Species Potentiates Colitis Sandra C. Kim, Susan L. Tonkonogy, R. Balfour Sartor M1086 The Composition of the Faecal Flora of 1BD-Patients and Their Unaffected Twin-Siblings Daisy Jonkers, Matielle Romberg-Kamps, Martine Hesselink, Reinhold Stockbrugger M1074 M1075 Monocytes are Highly Sensitive to c. difficile Toxin A- Induced Cell Death, the Mode of Which is Dependent upon Toxin Concentration Katie Solomon, Adrian Robins, Yashwant R. Mahida Gnotobiotic Mice Colonized with Helicobacter bills Demonstrate Antigen-Specific Immune Responses to Resident Enteric Flora Albert E. Jergens, Michael Wannemuehler, Andrea Dorn, Jenny Wilson, Abigail Lozano, Zhipiflg Liu, Jesse Hostetter M1087 The Distribution of the Mucosal Bacterial Species from IBD and Control Human Colon and Terminal Ileum Timothy H. J. Florin, Sharise P. Heazlewood, Anthony R. Fowler, Justice C. F. Baiano, Denis O. Krause, Xin Wang, Linda L. Blackall AM-5:00 PM Hall F M O N D A Y MAY 17 M1076 M1077 M1078 M1079 M1080 M1081 M1082 Cooperative Interactions Between Flagellin- and SopE2- Activated Signals Lead to Increased Epithelial IL-8 Secretion in Response to Salmonella Infection Fu-Chen Huang, Adam Werne, Qian Li, Edouard E. Galyov, W. Allan Walker, Bobby J. Cherayil Muramyl Dipeptide (MDP) Induces Nod2-Dependent Secretion of Proinflammatory Cytokine in Human Colon Epithelial Cells Yusong Gong, Min Zhang, Chuan-Min Chen, Qiong-Duan Zheng, Tian-Jian Chen, Jian-Jun Chen Influence of Enterobacteria on T Lymphocyte Migration in Intestinal Mucosa -in situ Observation Under Germ Free or SPF Conditions- Koichi Takebayashi, Yoshikazu Tsuzuki, Koji Matsuzaki, Ryota Hokati, Yoshikiyo Okada, Atsuhiro lwai, Atsushi Kawaguchi, Shigeaki Nagao, Kazuro Itoh, Soichiro Miura Preferential Depletion of Mucosal CD4 + V~2 y~t Cells Does Not Account for the Inverted V82:VS1 Ratio in HIV Infection Michael A. Poles, Amir Horowitz, Saurabh Mehandru, Michael Shim, Lisa Schwartz, Jeanine Daly, Patricia Sun, David Ho, Linqi Zhang Lactobacillus Prevents the Invasion and Inflammatory Response Caused by Salmonella Infection in the Human Intestine Jae Sung Ko, Meredith Hass, Luke Scheidler, W. Allan Walker, N. Nanda Nanthakumar The Role of CD8 + and CD4 + T Cells in Jejunal Injury and Proliferation of lntraepithelial Lymphocytes in Giardiasis Linda Yu, Kevin Scott, Andre Buret Colonic IgA-Produeing Cells and Macrophages are Reduced in Recurrent and Non-Recurrent C. difficle- Associated Diarrhoea Shawinder S. Johal, Christian P. Lambert, Joyce Hammond, Yashwant R. Mahida Sponsored by: Intestinal Disorders INTESTINAL EPITHELIAL TRANSPORT: ABSORPTION AND SECRETION M1088 M1089 M1090 M1091 M1092 M1093 M1094 Intestine-specific Deletion of MTP Reveals Differential Transport Functions in Enterocyte Lipid Absorption Yah Xie, Jianyang Luo, Elizabeth Newberry, Sylvie Robine, Nicholas O. Davidson DRA (Down Regulated In Adenoma) Binds in vitro to the PDZ Adapter PROTEINS E3KARP, EBP50 AND PDZK1, but Binding May Be Negatively Regulated in vivo Georg Lamprecht, Heidi Rossmann, Dorgam Natour, Julia Meier, Andreas Heil, Chris Yun, Walter Fiehn, Michael Gregor Characterization of the 5'-Regulatory Region of the Human Thiamin Transporter SLC19a3 Gene Both in vitro And in vivo in Transgenic Mice Svetlana M. Nabokina, Harold M. Said Brush Border (BB) NHE3 Activity Is Lipid Raft Dependent Rakhilya Murtazina, Xuhang Li, Mark Donowitz Regulation of Human Ileal Bile Acid Transporter in Caco2 Cells by Phorbol Ester, PMA Waddah A. Alrefai, Zaheer Sarwar, Seema Sakseua PKC Activation Stimulates MCT1 Promoter Activity in Caco2 cells Seema Saksena, Ravinder K. Gill, Sangeeta Tyagi, Waddah A. Alrefai, Alip Borthakur, Krishnamurthy Ramaswamy, Pradeep K. Dudeja Transport Characteristics of the Human Intestinal Anion Exchanger DRA (Down Regulated in Adenoma) in Transfected HEK293 Cells Georg Lamprecht, Susannah Baisch, Elena Schoenleber, Michael Gregor M1083 Chronic Cryptosporidium parvum Infection in SCID Mice Results in Failure of Innate Interferon-"/Response and Mortality Stuart McDonald, Patricia Smith, Greg Bancroft, Vincent McDonald M1095 Altered Basolateral K + Channel Activity as the Basis of Epithelial Cell Depolarization in Ulcerative Colitis Geoffrey I. Sandle, Adel A1-Hazza, Qadir Aziz, Malcolm Hunter P-158 ~ Denotes DDW Poster of Distinction

48 r POSTER SESSIONSmBASIC SCIENCE M1096 M1097 M1098 M1099 Mll00 Mll01 Ml102 Ml103 Ml104 Ml105 Ml106 Ml107 Ml108 Ml109 The Role of Upstream Stimulatory Factors 1 and 2 (USF1 and USF 2) in Regulation of Human Monocarboxylate Transporter 1 (MCT1) Promoter Alip Borthakur, Christos Hadjiagapiou, Waddah A. Alrefai, Krishnamurthy Ramaswamy, Pradeep K. Dudeja Prolonged Exposure to Physiological Concentrations of Dihydroxy-Bile Acids Inhibits Colonic Epithelial C1 Secretion Alan F. Hofmann, Kim E. Barrett, Stephen J. Keely Inhibition of Arachidonic Acid Metabolites Production Reverses the Inhibition of Na-Glucose Co-Transport in the Chronically Inflamed Intestine Steven Coon, David Quinn, Sheik Wisel, John Fromkes, Uma Sundaram PI3K Contributes to the Inhibitory Effect of Growth Hormone on Calcium-Dependent Chloride Secretion in T84 cells Jimmy Y. C. Chow, Kim E. Barrett CaSR Modulates cgmp Induced Fluid Secretion in Colonic Crypts Kumudesh Sritharan, Markus Deichstetter, Achim Seeger, John Geibel, Rainer Geibel, John-Scott Pershing, Christian Prinz, John Geibel Role of Actin Cytoskeleton in Serotonin-Mediated Inhibition of Na+/I-I + Exchange (NHE) Activity in Caco- 2 Cells Ravinder K. Gill, Jerrold R. Turner, Jaleh Malakooti, Waddah A. Alrefai, Krishnamurthy Ramaswamy, Pradeep K Dudeja Substrate-Induced Inhibition of the Serotonin Transporter in Human Intestinal Epithelial (Caco-2) Cells Ravinder K Gill, Seema Saksena, Waddah A. Alrefai, Sangeeta Tyagi, Zaheer Sarwar, Pradeep K. Dudeja Carbachol Increases Na+/HCOf Cotransport Activity in Murine Proximal Colon Oliver Bachmann, Dorothea Reichelt, Michael P. Manns, Ursula Seidler STa Stimulates a Novel Bicarbonate Secretory Pathway in CFTR Knockout Mice Zachary M. Sellers, Anders Smith, Hui Dong, Kim E. Barrett Modulation of Human Ileal Bile Acid Transporter by 25- Hydroxycholesterol in Caco2 Cells ' Waddah A. Alrefai, Zaheer Sarwar, Ravinder K. Gill Magnesium Deficiency-Induced Inflammation Alters Colonic Epithelial Cell Function Blaine A. Tuft, Minela Fernandez, Bradley Stanton, Justin Elfrey, Kathleen B. Madden, Carolyn Sullivan, William Weglicki, Terez Shea-Donohue Dexamethasone Activation of NHE3 and SGK1 in Epithelial Cells Dongsheng Wang, C. Chris Yun Weanling but not Adult Rabbit Distal Colon Exhibits Net Bile Acid Absorption: Putative Roles for Na- Dependent Bile Acid Transporter (ASBT) and Lipid Binding Protein (LBP) Jainuch Kanchanapoo, Dirk Weihrauch, Mei Ao, Pawinee Piyachaturawat, Mrinalini C. Rao Oral SPI-0211 Increases Intestinal Fluid Secretion And Chloride Concentration Without Altering Serum Electrolyte Levels Ryuji Ueno, Hiroyoshi Osama, Tsuyoshi Habe, Kory Engelke, Myra Patchen Mlll0 Mllll Mll12 Ml113 Mll14 Mll15 Ml116 Ml117 Mll18 Mll19 Ml120 Putative Anion Transporter (PAT1): Expression and Membrane Localization in the Human Intestine Seema Saksena, Ravinder K. Gill, Sangeeta Tyagi, Waddah A. Alrefai, Krishnamurthy Ramaswamy, Pradeep K. Dudeja Talniflumate (Lomucin tin) Is an Inhibitor of Intestinal Cl/Hco3" Exchange and Increases the Survival of Cystic Fibrosis Mice Nancy M. Walker, Kathryn T. Boyle, Janet E. Simpson, Lane U Clarke Basal Ion Flux of the Ileum but Not the Colon Is Altered in the Streptozotocin Diabetic Rat Abigail Forrest, Mike Parsons Apical Ammonium Inhibition of camp-stimulated Chloride Secretion in T84 Cells Is Bicarbonate Dependent Roger T. Worrell, Alison Best, Jennifer Oghene, Jeffrey B. Matthews The Rapid Repression of DMT-1 by the Hepatic Antimicrobial Peptide Hepcidin Naveen Sharma, Chris Tselepis, Jeffrey Butterworth, Brian Cooper, Tariq Iqbal Intestinal Adaptation of P-Glycoprotein Expression and Activity During DSS Induced Colitis in Rat Marion Buyse, Genia Radeva, Benjamin Beaufils, Andre Bado, Robert Farinotti Colitis Induced Changes in Murine Epithelial Cell Function Minela Fernandez, Kathleen B. Madden, Blaine Tuft, Justin E. Elfrey, Carolyn A. Sullivan, Aiping Zhao, Terez Shea- Donohue Altered Intestinal Metabolic Enzyme Activities in Leptin-Deficient Obese Mice Following Small Bowel Resection 'James M. Kiely, Jae H. Noh, Carol L. Svatek, Henry A. Pitt, Deborah A. Swartz-Basile CFTR Expression Is Increased in Chronically Inflamed Small Intestine Crypts Hui Zhang, Raju Vulapalli, Steven Coon, Uma Sundaram, Srisaila Basavappa Differences in Function and Structure of NHERFI and NHERF2 in camp and cgmp Regulation of NHE3 Boyoung Cha, Jae Ho Kim, Hans Hutt, Janani Nadarja. Mirza Zizak, Whaseon Kwon, C. Ming Tse, Chris Yun, Hugo dejonge, Mark Donowitz Intestinal Na +/I-I + Exchange Activity and Molecular Events Downstream Interferon-Gamma Receptor Activation Fernando J. Magro, Sonia Fraga, Patricio Soares-da-Silva AM-5:00 PM Hall F Mortal Convention Center Sponsored by: Intestinal Disorders INTESTINAL MOLECULAR BIOLOGY AND GENE REGULATION Ml121 Histone Deacetylase Activity Modulates C/EBP- Dependent Regulation of Acute Phase Response Gene Serum Amyloid A in Intestinal Epithelial Cells Mylene Blais, Naomie Turgeon, Sophie Routhier, Jean- Francois Tessier, Claude Asselin i Denotes DDW Poster of Distinction P-159

49 M O N D A Y MAY 17 Ml122 Ml123 M1124 Ml125 Ml126 Ml127 Ml128 Ml129 Ml130 Ml131 Ml132 Ml133 Ml134 8 Ml135 Ml136 I Disruption of TGF-]~ Signaling: Aberrant SI Phenotype in ELF Deficient Mice and Human Intestinal Transplant (ITx) Rejection Thomas Fishbein, Anan H. Said, Michael A. Zasloff, Varalakshmi Katuri, Yi Tang, Lloyd Mayo/, Bibhuti Mishra, Lopa Mishra Interaction Between the Transcription Factor CfEBP8 and the DNA Repair Factor Kn70/86 Genevieve Doyon, Amy Svotelis, Klaus Klarskov, Claude Asselin AMP-Activated Protein Kinase Down-Regnlates Intestinal SGLT1-Mediated Glucose Transport and Induces GLUT2-Dependent Uptake John Walker, Humberto Jijon, Hugo Diaz, Thomas Churchill, Karen Madsen Structural Basis for Molecular Elasticity Exhibited by the Laminin LG4-5 Dystroglycan-Binding Domain Richard Gilbert, Sebastian Heersink, Marc D. Basson, Christine Ortiz Gene Delivery and Serotype Tropism Using Recombinant Adeno-Associated Virus Vectors in Colonic Epithelial Cells Steven Polyak, Cathryn Mah, John F. Valentine Modulation of Adenoviral Transduction in Caco-2 Cells Filippos Kesisoglou, David Fleisher, Ellen M. Zimmermann Cloning and Characterization of Bitter Taste Receptors in Murine Enteroendocrine Cells STC-1 Shuping V. Wu, James Sinnett-Smith, Steven H. Young, Peter L. Chew, Joseph R. Reeve Jr., Enrique Rozengurt Biliverdin Blunts Sepsis-Induced Expression of Pro- Inflammatory Mediators and Intestinal Atony Marcus Overhaus, Beverley Moore, Betlehem A. Flynn, Anthony J. Bauer Anti-Angiogenic Effect of Cyclosporin A in Human Intestinal Microvascular Endothelial Cells Parvaneh Rafiee, Jan Heidemann, Hitoshi Ogawa, Nathan Johnson, Pamela J. Fisher, Mona S. Li, Mary F. Otterson, Christopher P. Johnson, David G. Binion Trypsin Cleaves Intestinal Alkaline Sphingomyelinase from Mucosa and Enhances the Sphingomyelinase Activity Jun Wu, Ake Nilsson, Rui-Dong Duan Intestinal Gene Transfer via Recombinant Adeno- Associated Virus Serotype 2 (raav2) in Pure and Co- Culture Models of Human Intestinal Lineages Shiue-Cheng Tang, Athanassios Sambanis, Eric Sibley Effect of Sulindac on Acute Apoptotic Response to Carcinogen in P53 Knockout Mice Ying Hu, Richard K. Le Leu, Graeme P. Young Transcriptional Activation of Myosin Light Chain Kinase Mediates TNFoL-Induced Barrier Dysfunction W. Vallen Graham, Fengjun Wang, Yingmin Wang, Jerrold R. Turner Cysteamine Alters Redox State, HIF-I~ Transcriptional Interactions and Reduces Duodenal Mucosal Oxygenation: Novel Mechanisms of Duodenal Ulceration Tetyana Khomenko, Xiaoming Deng, Zsuzsanna Sandor, Martin R. Jadus, Andrzej Tarnawski, Sandor Szabo Effects of Glucocorticoids on Expression of P- glycoprotein and Glucocorticoid Receptor in the Intestinal Epithelium Fiona Moodie, Valerie Lyons, Jack Satsangi, Jonathan R. Seckl POSTER SESSIONS--BASIC SCIENCE SSAT Poster Session AM-5:00 PM Hall F BILIARY: BASIC Ml137 Ml138 Ml139 M1140 Ml141 Optimization of Conditionally Replicative Adenovirus for Cholangiocarcinoma Pedro J. Ramirez, Hidetaka A. Ono, Julia Dawdova, Victor Krasnykh, David T. Curiel, Masato Yamamoto, Selwyn M Vickers Choice of Suture in Biliary Surgery-Does It Really Matter? Dion L. Franga, David Wicker, Naren Gupta, Thomas R. Gadacz, Jeffrey Lee, Robert G. Martindale Optimising Infectivity Enhanced, Conditionally Replicative Adenovirus for Gallbladder Cancer Gene Therapy Yaman Tekant, Pedro Ramirez, Hidetaka Ono, Viktor Krasnykh, Julia Dawdova, Tatyana Gavrikova, Long Le, David Curie1, Selwyn Vickers, Masato Yamamoto Swine Benign Biliary Stricture Model Johanna Laukkarinen, Pierce Chow, Juhani Sand, Sidney Yu, S. Somanesan, Irene Kee, In Chin Song, Teck Hin Ng, lsto Nordback Initial and Long-term Outcome of Biliary Bypass Surgery in Peri'ampullary and Pancreatic Carcinoma K. F. D. Kuhlmann, D. van Poll, Steve de Castro, O. R. C. Busch, T. M. van Gulik, Huug Obertop, D. J. Gouma SSAT Poster Session AM-5:00 PM COLON-RECTAL: BASIC Ml142 Ml143 Ml144 Ml145 Hall F Comparative Study of Epithelial Gene Expression in the Small Intestine Among Total Proctocolectomized, Dietary Sodium-Depleted and Aldosterone-Infused Rats Kouhei Fukushima, Shun Sato, Hiroo Naito, Yuji Funayama, Sho Haneda, Kazuhiro Watanabe, Chikashi Shibata, Iwao Sasaki Phosphoramidon, a Novel Matrix Metalloproteinase Inhibitor, Inhibits Significantly Tumor Growth Independently of the Application Route in a Rat Model of Peritoneal Carcinomatosis Arndt Hribaschek, Frank Meyer, Karsten Ridwelski, Matthias Pross, Peter Habermann, Walter Halangk, Hans Lippert Increased Severity of Intestinal Inflammation in the Stat6 Knockout (Star6(-/-)) Mouse Lisa Poritz, Kristian Garver, Walter Koltun, Wen Jie Zhang, Eva Galka, Leo Fitzpatrick HnRNP A1 is a Novel Marker for Human Colorectal Carcinoma Kazunori Shibao, Yoshifumi Nakayama, Koji Onitsuka, Yuzuru Inoue, Takefumi Katsuki, Koji Kadowaki, Yosuke Tsurudome, Keiji Hirata, Tatsuhiko Sako, Naoki Nagata, Hideaki Itoh P Denotes DDW Poster of Distinction

50 POSTER SESSIONS~BASIC SCIENCE SSAT Poster Session AM-5:00 PM Hall F ESOPHAGEAL: BASIC Candidate Biomarkers in the Development of Barrett's Ml146 Adenocarcinoma; CDX-2 & TSPAN-1 Daniel Vallboehmer, Jeffrey H. Peters, Sylke Schneider, Nahid Hamoui, Kazumi Uchida, Hidekazu Kuramochi, Daisuke Shimizu, Parakrama T. Chandrasoma, Kathleen D. Danenberg, Peter Danenberg, Tom R. DeMeester Oxidative Injury in Gastroesophageal Reflux Disease Ml147 (GERD) Does Not Disappear After Antireflux Surgery Jarmo A. Salo, Tuomo K. Rantanen, Jari V. Rasanen, Martti Farkkila, Eero I. Sihvo Absorbable Versus Non-Absorbale Mesh Repair of Ml148 Congenital Diaphrgmatic Hernias in a Growing Animal Model Rodrigo Gonzalez, Mark L. Wulcan, Samer G. Mattar, Edward Lin, Bruce J. Ramshaw, C. Daniel Smith Survey of 104 Genes for DNA Methylation Markers in Ml149 Esophageal Adenocarcinoma Tasha A. K. Gandamihardja, Mihaela Velicescu, Daniel Weisenberger, Kimberly Siegmund, Jeffrey A. Hagen, Jeffrey H. Peters, Steven R. DeMeester, Peter F. Crookes, Cedric G. Bremner, Tom R. DeMeester, Peter W. Laird Proteomic Analysis of SEG-1 Human Barrett's-Associated Ml150 Esophageal Adenocarcinoma Cells Treated with Keyhole Limpet Hemocyanin Sara Zulfiqar, Linda Vona-Davis, Tim Vincent, David W. McFadden SSAT Poster Session AM-5:00 PM Hall F HEPATIC: BASIC Mll51 Ml152 Ml153 Ml154 Ml155 Over-expression of AIF-1 in Liver Allografts and Peripheral Blood Correlated with Acute Rejection After Transplantation Yuichi Nagakawa, Shuji Nomoto, Yukihiko Kato, Andrew S. Klein, Zhaoli Sun Hepatocyte Specific Metabolic Activity Is Inducible in Adult Liver Stem Cells Isolated from Rodent Bone Marrow by Interleukin-3 Daniel Inderbitzin, Adrian Keogh, Guido Beldi, Markus Gass, Peter Studer, Deborah Stroka, Beat Gloor, Daniel Candinas Partial Hepatectomy Does Not Enhance the Occurrence of HCC in Cyclin D10verexpression Transgenic Mice Christopher D. Anderson, Natasha G. Deane, R. Daniel Beauchamp, Ravi S. Chari Tumor Antigen-Specific, CD8 + T-Cell Tolerance in a Murine Model of Spontaneous Hepatocellular Carcinoma Marcela Jimenez, James Staveley-O'Carroll II, Kevin F. Staveley-O'Carroll Nuclear Factor-KB and Cyclooxygenase-2 Inhibitors Provide Synergistic Inhibition of Hepatocellular Carcinoma Cellular Proliferation Possibly Through Modulation of IKBA Earl A. Gage, Matthew C. Ralstin, Atit Patel, Michelle T. Yip-Schneider, Keith D. Lillemoe, C. M. Schmidt Ml156 Ml157 Ml158 Ml159 Edaravone (MCI-186), a New Free Radical Scavenger, Reduces Oxidative Liver Damage Caused by Ischemia- Reperfusion Tomoya Abe, Michiaki Unno, Yu Katayose, Toshiki Rikiyama, Seiki Matsuno Oncolytic Mutant Herpes Vi/'~ ~ Hepatoma Cells Through a Mitoggl~ ~i~el~o~l Kinase (MAPK) - Depel/.~ ~ " ~ T~ ~:~, r~s~'adusumilli, Teresa Kim, Michael Mtll~a/t, Brendon Stiles, Yuman Fong Pharmacological Effects of Recombinant Growth Hormone on Rat Liver Cirrhosis Shuang Chen, Hongtao Wang, Jie Wang, Jishen Chen, Qingjia Ou Magnetic Resonance Imaging Provides Accurate Volume Determination in Regenerating Mouse Liver Daniel Inderbitzin, Christoforos Stoupis, Markus Gass, Guido Beldi, Adrian Keogh, Deborah Stroka, Peter Vock, Beat Gloor, Daniel Candinas SSAT Poster Session AM-5:00 PM Hall F PANCREAS: BASIC M1160 Ml161 Ml162 Ml163 Ml164 Ml165 M1166 Ml167 Ml168 Utilizing Tumor Hypoxia to Augment Viral Oncolytic Therapy in Pancreatic Adenocarcinoma Maura Reinblatt, Richard H. Pin, Yuman Fong Prostaglandin E2 (PGE2) Enhances Pancreatic Cancer Invasiveness Through an ETS-1-Dependent Induction of MMP-2 Hiromichi Ito, Mark Duxbury, Eric Benoit, Thomas E. Clancy, Michael J. Zinner, Stanley W. Ashley, Edward E. Whang SSTR1 Gene Ablation Causes Islet Hyperplasia and Insulinopenic Glucose Intolerance Xiao-Ping Wang, Michael A. Norman, Jia Yang, Franco J. DeMayo, Jonas Magnusson, F. Charles Brunicardi Bile-Pancreatic Juice Exclusion Activates JNK and Increases IL-1B Production in Ligation-lnduced Acute Pancreatitis Isaac Samuel, Smita Zaheer, Kiwhoon Lee, Asgar Zaheer Pancreatic Proteases Initiate Leukocyte-Endothelial Interaction in vitro and in Experimental Acute Pancreatitis Tobias Keck, Veronika Friebe, Andrew U \Varshaw, Ernst von Dobschuetz, Gerald Waneck, Bozena Antoniu, Stcfan Benz, Carlos Fernandez del-castillo RNAi-Mediated NF-KB RelA Suppression Sensitizes Pancreatic Cancer Cells to TNF-e~ Induced Apoptosis Jirong Bai, Charles Vollmer Jr., Mark P. Callery Notchl Signaling in Pancreatic Cancer Chris M. Schussler-Fiorenza, Jennifer Carpenter, Jamie Van Gompel, Muthusamy Kunnimalaiyaan, Herbert Chen Dexamethasone Mediates Protection Against Acute Pancreatitis via Upregnlation of Pancreatitis-Associated Protein Emad Kandil, Yin-Yao Lin, Domenico Viterbo, Victor Occasio, Martin Bluth, Michael Zenilman Autoimmune Activation and Glucose Intolerance in bsstr5-/- Mouse Model Xiao-Ping Wang, Jie Yang, Michael A. Norman, Franco J. DeMayo, Jonas Magnusson, F. Charles Brunicardi Denotes DDW Poster of Distinction P- 161

51 POSTER SESSIONSmBASIC SCIENCE Ml169 Ml170 Ml171 Ml172 Ml173 Mll74 Ml175 Ml176 Suramin Inhibits Not Only Tumor Growth and Metastasis but Also Angiogenesis in Experimental Human Pancreatic Cancer Andreas S. Porebski, O. Joe Hines, Howard A. Reber, Heinz J. Buhr, Hubert G. Hotz Serum MICA Levels in Pancreatic Cancer Patients Kaare J. Weber, Geetha Rao, Roderick Quiros, Xiulong Xu, Richard A. Prinz Pancreatitis Associated Protein (PAP) Genetic lsoforms Emad Kandil, Yin-Yao Lin, Martin Bluth, Michael Zenilman Reduction of the Bacterial Translocation in Experimental Acute Pancreatitis Using Pentoxifylline Andre S. Matheus, Cintia Y. Morioka, Ana Maria M. Coelho, Sandra N. Sampietre, Renato S. Godoy, Lourenilson J. Souza, Jose Jukemura, Jose Eduardo M. Cunba, Marcel C. C. Machado Staple Line Reinforcement with an Absorbable Polymer Membrane in Laparoscopic Distal Pancreatectomy and Partial Splenectomy Diminishes Pancreatic Duct Leak and Hemorrhage Esther C. J. Consten, Michel Gagner, Sergio Bardaro, Luca Milone The Peroxisome Proliferator-Activated Receptor-Gamma- Specific Agonist, Troglitazone, Decreases the Severity of Acute Pancreatitis In Vivo Sharon Sudarshan, Matthew A. Firpo, Michael D. Rollins, Yuanlin Shao, Brooke Hermanson, Sean j. Mulvihill, Robert E. Glasgow Suicide Gene Therapy of Pancreatic Cancer with Cytosine Deaminase: A Promising in vitro Tool Nicoletta Gallo, Paola Fogar, Filippo Navaglia, Daniela Basso, Eliana Greco, Carlo-Federico Zambon, Alessandra Falda, Cristina Durante, Claudio Pasquali, Cosimo Sperti, Mario Plebani, Sergio Pedrazzoli Hypertonic Solution (NaCl 7.5%) Reduces Mortality in Experimental Pancreatitis Marcel C. C. Machado, Ana Maria M. Coelho, Vera Pontieri, Sandra N. Sampietre, Niha A. T. Molan, Andre S. Matheus, Francisco G. Soriano, Irineu T. Velasco SSAT Poster Session AM-5:00 PM Hall F SMALL BOWEL: BASIC Ml177 8 Ml178 8 Ml179 Ml180 Acidosis Stimulation of Intestinal Arginine Absorption Is Mediated by Protein Kinase C and Mitogen-Activated Protein Kinases Haroon A. Choudry, QingHe Meng, Anne M. Karinch, ChengMao Lin, Wiley W. Souba Jr., Ming Pan Proteasome Gene Up-Regulation: A Possible Mechanism for Intestinal Adaptation David M Otterbum, L. G. Arthur, Shaheen J. Timmapuri, Suzanne M. McCahan, Marshall Z. Schwartz Enteral L-Arginine Improves Tolerance to Mesenteric Ischemia/Reperfusion (IR) in Diabetic Rats Sunny K. Whiteman, Bradford J. Scanlan, Justin E. Elfrey, Allen Chap, Brian Chap, Aiping Zhao, Terez Shea-Donohue P38 MAPK Modulates ERK 1/2 During Ischemic Stress in Model Intestinal Epithelia Joshua Mammen, Karl Matlin, Jeffrey Matthews Ml181 Ml182 M1183 M1184 Ml185 Sepsis Induces Inflammation of Lung Parenchyma Via Gut-Derived Mediators in Rats Joerg Glatzle, Mario H. Mueller, Wendelin Wilhelm, Guido Seitz, Markus Kueper, Helen E. Raybould, Martin E Kreis, Tilman T. Zittel Nitrergic Mechanisms Mediating Inhibitory Control of Longitudinal Smooth Muscle Contraction in Mouse Small Intestine Tatsuya Ueno, Judith A. Duenes, Abdalla Zarroug, Michael G. Sarr ATB /ASCT2 Message Expression in Residual Bowel Is Decreased By Massive Enterectomy and Increased By Trophic Factor (TF) Treatment Nelly E. Avissar, Thomas R. Zieglar, Li H. Gu, Liana Toia, Edward C. Ray, Jorge Berlanga-Acosta, Harry C. Sax Protein Kinase C Mediates Transforming Growth Factor- Beta Stimulation of Intestinal Glutamine Absorption QingHe Meng, Haroon A. Choudry, ChengMao Lin, Anne M. Karinch, Ming Pan High Yield Cytokine Screening in Gastrointestinal Careinoid Tumors Jamie J. Van Gompel, Muthusamy Kunnimalaiyaan, Herbert Chen SSAT Poster Session AM-5:00 PM Hall F STOMACH: BASIC M1186 Ml187 Ml188 Ml189 Optimization of Infectivity Enhanced Conditionally Replicative Adenoviral Vectors for the Gene Therapy of Gastric Cancer Hidetaka A. Ono, Julia G. Davydova, Long P. Le, Pedro J. Ramirez, Tatyana Gavrikova, Victor N. Krasnykh, Chikara Kunisaki, Hiroshi Shimada, David T. Curiel, Masato Yamamoto Comparative Evaluation of Gastrointestinal Transit and Immune Response Between Laparoscopic and Open Gastrectomy in a Porcine Model Kazuki Ueda, Ronald Matteotti, Abroad Assalia, Michel Gagner Postoperative Gastropyloroduodenal Motility and Gastric Emptying After Pylorus-Preserving Gastrectomy in Dogs Naruo Kawasaki, Koji Nakada, Tomoko Takahashi, Yoshiyuki Furukawa, Nobuyoshi Hanyu, Katsuhiko Yanaga Helicobacter Pylari Infection and Gastric Cancer-Cause or Effect?-Pathological Evidence Rodrigo Perez, Claudio Bresciani, Kyioshi Iryia, Carlos E. Jacob, Renato A. Iwashita, Bruno P. Soriano, Bruno Zilberstein, Joaquim Gama-Rodrigues P Denotes DDW Poster of Distinction

52 POSTER SESSIONS--CLINICAL SCIENCE CLINICAL SCIENCE AASLD Poster Session Authors are required to be present during the Poster Session from 12:00-2:00 pm. Those posters identified as DDW Posters of Distinction have received review scores that place them within the top 10% of all posters. We encourage you to make them a priority as you visit the poster session. AM-5:00 PM Hall F CHOLESTATIC LIVER DISEASE Serum Markers of Fibrosis in Primary Biliary Cirrhosis Ml190 Yonas Getachew, Esther Oh, Scott A. Mills, Melissa Contos, Rodney Markin, Raphael Rubin, Donald Wheeler, Nancy Flye, Beverly Huet, Burton Combes, Marlyn Mayo Macrophage Phagocytosis of Apoptotic Cells Is Defective Ml191 in PBC Jorge Allina, Marialsabel Fie1, Carmen Stanca, Nidhi Tandon, Bin Hu, Samuel Sigal, Nancy Bach, Joseph Odin Fluoxetine for the Treatment of Fatigue in Primary Ml192 Biliary Cirrhosis Jayant Talwalkar, Roberta Jorgensen, Jill Keach, Jan Petz, Keith Lindor Ml193 Ml194 Ml195 Ml196 Ml197 Ml198 Ml199 Parenchymal Function and Bile Duct Flow as Measured by Dynamic 99m TcoHIDA SPECT as Prognostic Tool in Primary Sclerosing Cholangitis Eduard Jonas, Erik Naslund, Jacob Freedman, Ragnar Befrits, Lennart Blomqvist, Anna-Karin Siosteen, Hans Jacobsson, Rolf Huhcrantz Effect of Apolipoprotein E Polymorphism on Treatment Response of UDCA and Metronidazole in PSC Martti A. Farkkila, Pekka Pikkarainen, Heimo Nurmi, Hannu U. Nuutinen, Anna-Liisa Karvonen Impact of MELD for Patients with Primary Sclerosing Cholangitis Awaiting Liver Transplantation K. D. Fairbanks, S. S. Solga, C. K. Cohen, K. S. Klein, Rudra Rai Epitope-specific Antibodies to Human Calreticu. lin in Primary Biliary Cirrhosis Wolfgang Kreisel, Kai-Wolfgang Roesler, Julia Riedel, Heinz Hoscbuetzky Increased Rates of Early Adverse Reaction to Azathioprine in Patients with Crohn's Disease Compared to Autoimmune Hepatitis: A Tertiary Referral Center Experience Jasmohan S. Bajaj, Kia Saeian, Rajiv R. Varma, Jose Franco, Joshua Knox, Jeanne Emmons, Judy Podoll, David G. Binion The Significance of Anti-Mitochondrial Antibodies (AMA) in Patients with Classical Autoimmune Hepatitis: Twenty-Eight Years of Follow-up Supriya Joshi, Maha Guindi, Jenny Heathcote Detection of Autoantibodies to the Nuclear Pore Complex gp210 in Primary Biliary Cirrhosis Patients by a New ELISA Gary L. Norman, Zakera Shums, Carol L. Peebles, Kiyomitsu Miyachi, Raleigh W. Hankins, Minoru Shibata, Etsuko Hashimoto, Hiroshi Miyakawa, Eng M. Tan M1200 M1201 M1202 Is a Leaky Gut Involved in the Pathogenesis of Intrahepatic Cholestasis of Pregnancy? Rodrigo L. Zapata, Maria Isabel Jiron, Ismael Hemandez, Lorena Sandoval, Joaquin Palma, Humberto Reyes, Manuel Sedano, Martin Gotteland, Carlos Munoz, Marcelo Lopez Osteopenia and Osteoporosis in Patients with Primary Sclerosing Cholangitis Cannot Be Predicted by Severity of Liver Disease Mical S. Campbell, Gary R. Lichtenstein, Andrew D. Rhim, Thomas W. Faust Temporal Changes in Severity of Osteopenia Before Liver Transplantation Maureen M. J. Guichelaar, Rebecca Kendall, Michael Malinchoc, Eileen J. Hay AASLD Poster Session AM-5:00 PM Hall F EPIDEMIOLOGY, DECISION ANALYSIS AND COST- EFFECTIVENESS M1203 M1204 M1205 M1206 M1207 M1208 M1209 M1210 M1211 Does a Single Light Alcohol Intake Affect the Serum C Virus RNA? Spilios Manolakopoulos, Michalis Economou, Sotiris Bethanis, Andriani Alevra, Nicoletta Mathou, Jiannis Vlachogiannakos, Georgia Vrioni, Sophia Levidiotou, Evangelos Vogiatzakis, Alec Avgerinos, Dimitrios Tzourmakliotis Group Education in Veterans with Hepatitis C Emily E. Williams, Ashlee J. Whitehead, Todd A. Harms, Robert E. Socberman, David W. Indest, Peter Hauser Central but Not Peripheral Obesity Is Associated with Cirrhosis-Related Death or Hospitalization: A Population-Based, Cohort Study George N. Ioannou, Noel S. Weiss, Edward J. Boyko, Kris V. Kowdley, Steven E. Kahn, Robert L. Carithers Jr., Jason A. Dominitz Population-Based Study of the Epidemiology of and the,. 'L~ Risk Factors for Pyogenic Liver Abscess : i:::i~%/ Gilaad G. Kaplan, Daniel B. Gregson, Kevin B. Laupland Why DoPatientswithHepatitisCNotAttendClinic :i:i i~i!!il Appointments? Results of a Focus Group Study Eric W. Dieperink, Holly Groom, Ramsey Cheung. Margaret Celebreze, Barry, Cohen, Samuel Ho. Mark Willcnbring : :':';:::::::)2~ Hepatitis C in a Large Cohort of Veterans: Population... 7: :7!i:::~... ~ Characteristics and Differences in Screening for Risk :::z :" 1 Factors. :-,: :,,: i::{7:.~7~ Mark L. \Villenbring, Eric W. Diepermk, Michael t<igs} b... Paul Thuras, Samuel B. Ho -:::-~-_- There are Three New Type 6 Variant Subgroups of HCV in Myanmar Toshiyuki Shinji, Yi Yi Kyaw, Katsunori Gokan, Shigem Okada, Norio Koide Observer vs. Operator Perceived Competence in Liver Biopsy with Ultrasound-Assisted Localization Darren B. Keller, Walter Coyle Coffee and Caffeine Consumption Protect Against Liver Injury in the United States Population Constance E. Ruhl, James E. Everhart Denotes DDW Poster of Distinction P-163

53 POSTER SESSIONS--CLINICAL SCIENCE M1212 M1213 M1214 M1215 M1216 Hepatocellular Carcinoma: The Magnitude of the Problem in Egypt Hesham I. ElMakhzangy, Gamal Esmat, Maissa Alraziky, E1- Saeed A. Aoun, Mostafa K. Mohamed The Effect of Hepatitis C Coinfection on the Risk of Fulminant Hepatic Failure in Patients with HIV in the HAART and Pre-HAART Eras Jennifer R. Kramer, Thomas P. Giordano, Julianne Souchek, Hashem B. El-Scrag Quality of Life in Persistent and Resolved HCV Infection Jeremy M. Lake, Benjamin Chan, Hugo R. Rosen, Anna Sasaki, Atif Zaman, Kenneth Ingram, Renee Rutledge, Glenn Eisen, Jonathan M. Schwartz Cost-Effectiveness of Peginterferon ~-2b plus Ribavirin Treatment of Chronic Hepatitis C with F1 Fibrosis John B. Wong, Thierry Poynard, Michael P. Manns, John G. McHutchison, Joann Harvey, Jamice K. Albrecht Utilization of Drug Insurance Services (Pharmacare) by Individuals Diagnosed with Hepatitis C Susan Kirkland, Kevork Peltekian, Jeff Scott, Ingrid Sketris, Atulya Saxena M1224 M1225 M1226 M1227 Characterization of Synthetic Ribozymes, U1 Chimeric Ribozymes and 10-23DNAzymes Directed Against HCV/ HBV in vitro Junqi Niu, Yanhua Ding, Feng Wang, Meixia Wang, Rui Hua, Xiaoyu Wen, Meimei Tian, Jinhui Zhang Long-term Treatment with Epoetin Alfa Maintains Ribavirin Dose and Hemoglobin Levels in Anemic HCV- Infected Patients Receiving Interferon/Ribavirin (IFN/ RBV) Therapy Paul J. Pockros, Mitchell L. Shiffman, Eugene R. Schiff, Nezam H. Afdhal, Mark S. Sulkowski, Zobair Younossi, Teresa Wright, Douglas T. Dieterich, Janice Jenkins, Gerhard J. Leitz, Peter J. Bowers Arrhythmias During Pegylated Interferon and Ribavirin Therapy for Chronic Hepatitis C: Observations from the WlN-R Trial Furqaan Ahmed, Ira M. Jacobson, Robert S. Brown Jr., John Vierling, Terry Box, J. L. Cochran, John B. Gross, Harry Matossian, Mordechai Rabinovitz, Geronimo Sahagun, Thomas E. Sepe, Clifford Brass Neurocognitive Changes in Patients with Chronic Hepatitis C Receiving Interferon Alfa-2b and Ribavirin Michael R. Kraus, Arne Schaefer, Michael Scheurlen M1217 Risk of Hepatitis E Virus Infection by Eating Uncooked Deer Meat Naoto Kitajima, Syuchin Tel, Syunji Ohhara, Yoshifumi Inoue, Masaharu Miki, Toshiyuki Yamatani, Yoshikazu Kinoshita, Kazuaki Takahashi, Shunji Mishiro M1228 Hemoglobin Decline Associated with Interferon and Ribavirin Therapy in Chronic Hepatitis C (CHC) Is Not Predictive of Sustained Virological Response (SVR) Anouk T. Dev, Keyur Patel, Andrew Muir, Marc Vallee, Dylan Matzinger, John McHutchison M O N D A Y MAY 17 M1218 M1219 M1220 Seroprevalence Of Hepatitis E in Nahavand, Iran: A Population-Based Study Mohammad Reza Zali, Mahnaz Taremi, Seyed Mehdi Mahmoud Arabi, Ali Ardalan, Amir Hoshang Mohammad Alizadeh, Shahin Ansari Cirrhosis Reduces the Response to Hepatitis A (HAV) Vaccination in Chronic Liver Disease Shilun D. Li, Asad Aziz, Jack Leya, Marc Kennedy, David H. Van Thiel Percutaneous Liver Biopsy in Chronic Hepatitis C patients with End Stage Renal Disease Is Safe Swati Pawa, Murray N. Ehrinpreis, Milton G. Mutchnick, Ravi Dhar, Firdous A. Siddiqui AASLD Poster Session AM-5:00 PM Hall F HEPATITIS C TREATMENT II M1221 M1222 Statistical Analysis of Combined Substitutions in NS5A of Hepatitis C Virus lb Infection and Standard or Pegylated Interferon plus Ribavirin Therapy Response Hisashi Moriguchi, Chifumi Sato Gene Expression Profiles of Patients with Chronic Hepatitis C (CH-C) Treated with Pegylated Interferon alfa-2b and Ribavirin (PEG-IFN/RBV) Zobair M. Younossi, Joanne Chan, Karen Schlauch, Jennifer Assmann, Christopher Santini, Janus Ong, Lisa Martin, Terry Gramlich, Linda McAllister, Sheng-Yung Chang M1229 M1230 M1231 M1232 M1233 M1234 Mutations of Hepatisi C Virus NS5B Region and the Response to Interferon plus Ribavirin Combination Treatment Kosei Hamano, Naoya Sakamoto, Nobuyuki Enomoto, Namiki Izumi, Yasuhiro Asahina, Masayuki Kurosaki, Eri Ueda, Yoko Tanabe, Shinya Maekawa, Mamoru Watanabe Pegylated Interferon (alpha-2b) And Ribavirin (Rebetol) For The Treatment Of HCV Infected Patients Who Failed Prior Therapy: Sustained Response Data Paul J. Gaglio, James Choi, David Zimmerman, Larry Heller, Robert S. Brown Jr. Retreatment with Pegylated Interferon Alpha-2b and Ribavirin in Patients with Chronic Hepatitis C Non Responders to Interferon Monotherapy or Interferon and Ribavirin Combination. A Prospective Randomized Pilote Study of Two Regimens: Induction Versus Regular Dose Pegylated Interferon Catherine Bapin, Pascale Fabbro-Peray, Sadia Hachemane, Dominique Larrey Impact of a Dedicated Hepatology Nurse on the Clinical Course and Quality of Life of Patients Treated with Rebetron Therapy for Chronic Hepatitis C Joanne Imperial, Mary Ahem Treatment of HCV Infected Patients, Including Non- Responders to PEG-IFN alfa2b/rbv, with PEG-IFN alfa2a/rbv: The Johns Hopkins Experience N. Zeng, C. K. Cohen, P. Schwartz, Rudra Rai HCV and HIV Coinfection: Impediments for Therapy Moises A. Garcia, Nalini M. Guda, Ahmad B. Shughoury, Iram Nadeem, Aboud Affi M1223 Cost-Effectiveness of Growth Factors During Hepatitis C Antiviral Therapy Michael K. Chapko, Jason A. Dominitz M1235 Estrogen Replacement Therapy Does Not Affect Therapeutic Outcome in Post-Menopausal Women Infected with Hepatitis C Matthew J. Hepburn, Norma S. Cantu, Maria G. Lapeer, Eric J. Lawitz P-164 ~ Denotes DDW Poster of Distinction

54 POSTER SESSIONS~CLINICAL SCIENCE M1236 M1237 M1238 M1239 M1240 M1241 M1242 M1243 M1244 M1245 M1246 M1247 Safety and Adherence to Peginterferon Alfa-2a (40KD) Plus Ribavirin (RBV) in Black Americans with Chronic Hepatitis C (CHC) HCV Genotype 1 Charles D. Howell, Lennox S. Jeffers, Sylvia Hu, Juan Carlos Lopez-Talavera Use of Dronabinol for Treatment of Common Side Effects of Chronic Hepatitis C Therapy Sara A. Levitan, Alison Uriel, Nickolas Kontorinis, Douglas Dieterich Efficacy of Interferon Alfa-2b and Ribavirin for the Treatment of Chronic Hepatitis C in Veterans with Psychiatric and Substance Abuse Disorders Malini Sahu, Edmund J. Bini The Effect of Induction Pegylated Interferon Alfa 2b and Ribavirin on Early Virologic Response in Genotype 1 Chronic Hepatitis C Eric J. Lawitz, Stephen A. Harrison, Norma S. Cantu, Mitchell Davis, Michael Perkel, Ravikumar Vemuru, Thaun Nguyen, Shailesh Kadakia, K. P. Ganesbappa, Kenneth Diamond, Harry Matossian, Terry D. Box, Elias Ghandour, Alamo Study Group Histopathological Effects of Pegylated and Standard Interferon in Responders and Non Responders Chronic Hepatitis C Genotype 4 Gamal Esmat, Khalid Zalata, Mohamed Metwally, Mohamed Abdel Harold, Amr Abouzied, Maissa El Raziky, Mohamed E1 Batanony, Thomas Strickland, Maria Sjogren Evaluation of the Safety and Efficacy of Combination Therapy with Interferon and Ribavarin in Patients with Chronic Hepatitis C and Significant Pretreatment Thrombocytopenia Raj Vuppalanchi, Paul Haynes, Paul Kwo, Lawrence Lumeng, Naga Chalasani The Effectiveness of Pegylated-Interferon and Ribavirin Combination Therapy for Chronic Hepatitis C in an Urban Clinic Setting Compared to Pivotal Clinical Trials Timothy C. Johnson, Samera Vaseer, Shahzad Iqbal, David J. Clain, Henry C. Bodenheimer Jr., Albert D. Min The Efficacy of Bovine Lactoferrin and fin-alpha 2b Combination Therapy Following 24-Week Regimen of Ribavirin plus IFN-Alpha 2b for Patients with Chronic Hepatitis C Who Did Not Respond to Prior IFN Monotherapy Koji Ishii, Yasukiyo Sumino, Mie Shinohara, Naol<o Takamura, Katsuhiko Matsumaru, Masao Shinohara, Hidenan Nagai, Manabu Watanabe, Kazumasa Miki, Koji Yamauchi, Susumu Teraguchi, Wataru Yamamuro Significance of Transferrin Iron Binding Capacity (TIBC) and Percent Iron Saturation as Predictors of Response Status Amongst Hepatitis C Genotype 1 Patients Dhiman Basu, Harsha V. Allu, Cinda H. Clark Experience with Pegylated Interferon and Ribavirin Therapy in Patients with Hepatitis C in an Urban VA Hospital Abhinandana Anantharaju, Linda Piersall, JoAnn Stegmaier, Bernard Nemchausky, Frank Iber, Nikunj Shah The Trend of Psychiatric Side Effects in US Veterans with Hepatitis C and History of Psychiatric Disorder Receiving Interferon Based Therapy Edward C. Paredez, David A. Blair, Vicki Sontag, Cynthia Geppert, Elizabeth Dettmer, Clifford Quails, Antoine Jakiche Antidepressant Use in Veterans with Hepatitis C Julie Nelligan, David W. Indest, Aaron D. Blackwell, Anna W. Sasaki, Marian Fireman, Peter Hauser AASLD Poster Session AM-5:00 PM HEPATOBILIARY IMAGING M M1249 M1250 M1251 M1252 M1253 M1254 M1255 M1256 M1257 Hall F Real Time 3D-Digital Reconstructed Imaging Using a 3D-angiography Workstation : Useful in the Diagnoses of Pancreatic and Cholangio Carcinomas Hitoshi Okubo, Fumihiko Komine, Masaki Shimojima, Hisato Harasawa, Toshihiro Shimizu, Yasuyuki Arakawa Therapeutic Response Using Contrast-Enhanced Harmonic Gray-Scale Sonography After Radiofrequency Ablation of Hepatocellular Carcinoma: Sonographic- Histopathologic Correlation Manabu Morimoto, Kazushi Numata, Kazuhito Shirato, Kazuya Sugimori, Atsushi Kokawa, Naohiko Tomita, Toshifumi Saitou, Toshio Imada, Katsuaki Tanaka Measurement of Hepatic Functional Reserve by Functional Liver Imaging: Correlation with Clinical and Laboratory Findings Jin-Woo Lee, Jung I1 Lee, Seok Jeong, Kye Sook Kwon, Don Haeng Lee, Pum-Soo Kim, Hyung Gil Kim, Yong Woon Shin, Young Soo Kim, Soon Gu Cho, Chang Hae Suh Hepatobiliary Imaging Using Technetium 99m Mmethoxyisobutylisonitrile: A Novel Technique for the Evaluation of Patients Suspected to Have Biliary Atresia Shereen Wageeh, S. E1-Refaey, Mortada Al-Shabrawi, Hanaa El-Karaksy, Nabeel Mobsen, Nehal E1-Koofy, Magd Kotb, Hassan H. A-Kader Positron Emission Tomography with F-18- Fluorodeoxyglucose in the Imaging of Liver Tumors Masazumi Fujimoto, Kazuhiko Mizuta, Toshihide Kawai, Maki Ishihara, Maki Inai, Yasunobu Toda Detection of Histopathological Differentiation with Hepatocellular Carcinoma by Enhancement Patterns Using Microbubble Contrast US Noritaka Wakui, Yasukiyo Sumino, Misato Sawa, Masahiro Kanayama, Yasuko Fujita, Hirokazu Shin, Masao Shinohara, Masao Shinohara, Manabu Watanabe, Koji Ishii, Kazumasa Miki Prevalence of Chilaiditi's Syndrome in Compensated Cirrotics and Its Uhrasound Detectability: A Prospective Study Hayato Nakagawa, Nobuo Toda, Takamasa Ooki, "fttl~:in:tga Yoshida, Hiroki Matsumoto, Michiharu Seki, Makoto Taniguchi, Kazumi Tagawa Prospective Evaluation of Hepatic Small Nodules: ~ ~ i Radiographic Findings and Probability of tlepatocellular Carcinoma Tomonori Fujishima, Ha~q~hiko Yoshida, Shuntaro Obi, Shuichiro Shiina, Norio Mine, Yuji Kondo, Noriyo ~ Yamashiki, Miho Kanda, Ryosuke Tateishi, Shinpei Sato. Takuma Teratani, Takashi [shikawa, Takat, Ka~abc'. Mas;,,... : :Z -- Omata.4:*~ Evaluation of Malignant Potential for Hepatocellular Carcinoma Using Magnetic Resonance Imaging Shotaro Enomoto, Hideyuki Tamai, Takayuki Kanno, Naoki Shingaki, Hiroki Maeda, Kosaku Moribata, Izumi Inoue, Takao Maekita, Mikitaka Iguchi, Kimihiko Yanaoka, Kenji Arii, Yasuhito Shimizu, Hiroya Nakata, Shintaro Kitauchi, Masao Ichinose Imaging the Biliary Tract : Comparable Roles of Ultrasonography and Magnetic Resonance Hanif J. Khan, Emmet J. Andrews, Mark J. Towers, Frank Cunningham, Joseph P. Mc Grath Denotes DDW Poster of Distinction P-165

55 M O N D A Y MAY 17 M1258 i Characterization of Focal Hepatic Tumors by SH U 508A High MI Contrast Enhanced Ultrasound Christoph Terkamp, Marco Doerge, Matthias Bahr, Michael P. Manns, Joerg Bleck, Michael Gebel AASLD Poster Session AM-5:00 PM HEPATOBILIARY SURGERY M1259 M1260 M1261 POSTER SESSIONSmCLINICAL SCIENCE I Hall F Clinical Efficacy of MELD Score Predicting Surgical Mortality & Morbidity in Patients with Liver Cirrhosis Yong Soo Kim, Sang Hoon Ahn, Kwan-Sik Lee, Chae Yoon Chon, Young Myoung Moon, Kwang Hyub Hahn Perioperative Outcome of Left Lateral Liver Resection Is Improved by Using Staple Line Reinforcement Technique Esther C. J. Consten, Michel Gagner, Luca Milone, Sergio Bardaro Outpatient Laparoscopic Cholecystectomy Is a Safe Procedure for the treatment of Gallstone Disease. Results from a Prospective Pilot Program in a Public Hospital in Chile Jorge A. Martinez-Castillo, Fernanda Bellolio, Marco Arrese, Marcel P. Sanhueza, Rodrigo Kusanovich, Julio R. Reyes, Ignacio Garcia-Huidobro, Marcelo Tortes, Marco Silberman AASLD Poster Session AM-5:00 PM Hall F Mortal Convention Center PORTAL HYPERTENSION: COMPLICATIONS OTHER THAN VARICEAL HEMORRHAGE M1262 M1263 M1264 M1265 M1266 M1267 Computerized Neuroscanning of Cirrhotics: Significant Impairment in the Absence of Overt Encephalopathy Charmaine Stewart, J. D. Ragland, Ruben Gut, Linda Stadheim, Gregory J. Gores Outcome of Factors Precipitating Porto-Systemic Encephalopathy Khalid Mumtaz, Noshaba Baig, Shahab Abid, Nadim Jafri, Saeed Hamid, Hasnain A. Shah, Wasim Jafri Oro-caecal Transit Time Is Significantly Increased in Hepatic Encephalopathy Mickael Bouin, Catherine Vincent, Karine Bouhier, Amelle Fatome, Marie Astrid Piquet, Jean-Claude Verwaerde, Thong Dao Objective Assessment of Cognitive Impairment in Cirrhotics Without Overt Encephalopathy: Implications for Diagnosis, Therapy and Public Policy Charmaine Stewart, Jane Cerhan, Glenn Smith, Linda Stadheim, Waiter Kremers, Donna Devine-Felmlee, Gregory J. Gores Diabetes Mellitus Is a Risk Factor for Hepatic Encephalopathy Nickolas Kontorinis, Elizabeth Ryan, Carmen Stanca, Samuel H. SigaI High Prevalence of Spontaneous Porto-Systemic Shunts in Cirrhotic Patients with Recurrent Hepatic Encephalopathy: A Case Control Study Oliviero Riggio, Cesare Efrati, Adolfo F. Attili, Carlo Catalano, Oriano Mecarelli, Francesca Nicolao, Stefania Angeloni, Lorenzo Ridola, Andrea Masini, Manuela Merli M1268 M1269 M1270 M1271 M1272 M1273 M1274 M1275 M1276 M1277 M1278 M1279 Minimal Hepatic Encephalopathy Diagnosed by Neuropsychological and Neurophysiological Tools in Patients with Liver Cirrhosis Senzolo Marco, Amodio Piero, Maria Cristina D'Aloiso, Fagiuoli Stefano, Del Piccolo Franco, Burra Patrizia Psychometric Evaluation of Patients with Cirrhosis and Control Subjects Before and After a 108g Amino Acid Challenge Hanan Mardini, Tamsin Manktelow, Christopher Record Transjugnlar Intrahepatic Portosystemic Shunt Versus Paracentesis in the Treatment of Refractory Ascites: A Meta-Analysis of Randomized Trials Jose M. Nieto, Sammy Saab Child C Cirrhosis and Refractory Ascites Are Not Contraindications to Hernia Repair Joo Kyung Park, Yoon Jun Kim, Jung-Hwan Yun, Hyo-Suk Lee, Chung Yong Kim, Jongwon Ha, Kyu Joo Park Comparison of the Effect of Albumin and Terlipressin in the Prevention of Postparacentesis Circulatory Dysfunction After Paracentesis of Tense Ascites: Preliminary Results of a Randomized Multicentric Study Jan Lata, Zdenek Marecek, Radan Bruha, Tomas Fejfar, Zdenek Hejda, Jiri Stehlik, Igor Tozzi, Petr Zdenek A Survey of Albumin Use in Liver Diseases in Gastroenterology Italian Centres Sergio Boccia, Loredana Simone, Caterina Rizzo, Giancarlo Spinzi Anemia Is a Major Determinant of Fatigue in Patients with Cirrhosis Nicholas Kontorinis, Carol Bodian, Louis DePalo, Douglas Dieterich, Samuel H. Sigal Anemia and Increased RDW Are Indicators of Liver Function and Prognosis in Advanced Cirrhosis: A Prospective Study Paul Arnold, Anastasios A. Mihas, Adil Habib, Souheil G. Abou-Assi, Leslie M. Williams, HoChong S. Gilles, Douglas M. Heuman Circadian Rhythm of Portal Blood Flow and Its Relation to Vasoactive Mediators in Patients with Cirrhosis Peter J. E. Schiedermaier, Lydia Koch, Artemio Mojon Ojea, Tilman Sauerbruch Predicting Clinically Significant Portal Hypertension in Chronic Hepatitis C Related Cirrhosis Adam Gordon, Joanne Mitchell, Brenda M. Morales, Michael J. Bailey, Peter W. Angus, Stuart K. Roberts Pregnancy After Placement of a Transjugular Intrahepatic Portosystemic Shunt (TIPS) in Two Patients with Budd-Chiari Syndrome (BCS) Bernhard Angermayr, Manfred Cejna, Monika Schmid, Johannes Lammer, Alfred Gangl, Markus Peck-Radosavljevic Transjugular Intrahepatic Porto-systemic Shunt (TIPS) and Liver Transplantation for Budd-Chiari Syndrome Augustin R. Attwell, Marcelo Kugelmas, Michael Ludkowski P Denotes DDW Poster of Distinction

56 POSTER SESSIONS~CLINICAL SCIENCE AASLD Poster Session AM-5:00 PM Hall F PORTAL HYPERTENSION: VARICES AND VARICEAL HEMORRHAGE Recurrence of Esophageal Varices and Rebleeding After M1280 Band Ligation for Esophageal Variceal Bleeding. A Long- Term Follow-Up Rodrigo L. Zapata, Patricio Ibanez, Arturo Acevedo, Mario Arcos, Sergio Carvajal, Daniel Cisternas, Jaime Lusbacher, Catherine Soto, Antonio Rollan Practice Patterns in Screening for Varices: A National M 1281 Survey Alfred S. Barritt IV, Miguel R. Arguedas Percutaneous Transhepatic Obliteration of Varices Using M1282 TH Glue Combined with Partial Splenic Embolization in the Management of Hemorrhage from Gastroesophageal Varices Chunqing Zhang, Kai Feng, Chengyong Qin, Hongwei Xu Prophylactic Transjugular Intrahepatic Portosystemic M1283 Shunt (TIPS) In Child's Class B Cirrhotics with Large Gastric Fundal Varices (LGFV): A Pilot Study Aijaz Ahmed, Prista Charuwom, Cynthia Leung, Joseph Lira, Ramsey C. Cheung, Daniel Sze, Mahmood Razavi, Carlos O. Esquivel, Emmet B. Keeffe MELD Score in Predicting Survival After Variceal M1284 Bleeding in Cirrhotic Patients with and Without Hepatocellular Carcinoma Lucio Amitrano, Maria Anna Guardascione, Raffaele Bennato, Francesco Manguso, Elisabetta Riccio, Antonio Balzano M1285 M1286 M1287 M1288 M1289 Predictive Factors of in-hospital Mortality in Acute Esophageal Variceal Bleeding Juan Carlos Munoz, Ivan Rascon-Aguilar, M. Mazen Jamal, Alex Vasquez, Mat Vasquez, Louis R. Lambiase, Kenneth J. Vega Medical Versus Endoscopic Intervention for Variceal Rebleeding in Cirrhosis: A Meta Analysis Jade D. Jamias, Ma Cecilia M. Sison, Ma Lourdes O. Daez Therapeutic Efficacy of Balloon-Occluded Retrograde Transvenous Obliteration in the Treatment of Gastric Varices in Cirrhotic Patients with Gastrorenal Shunt Gwang H. Balk, fin B. Kim, Dong J. Kim, Yo A. Sub, Chang S. Choi Transjugular Intrahepatic Portosystemic Shunt (TIPS) for Variceal Bleeding in Cirrhotic Patients: Comparison of Emergency and Elective Interventions Oliviero Riggio, Stefania Angeloni, Giorgia Nicolini, Filippo Salvatori, Fabrizio Fanelli, Daniela Pepino, Plinio Rossi, Adolfo Attili, Manuela Merli Factors Influencing Length of Stay in Patients Hospitalized with Gastro-Esophageal Variceal Bleed Kashif Anis, Hasnain A. Shah, Farhan A. Tirmizi, Khalid Mumtaz, Saeed Hamid, Shahab Abid, Wasim Jafri AM-5:00 Sponsored by: AGA; Liver and Biliary CLINICAL HEPATITIS: ETIOLOGY, DIAGNOSIS, AND NATURAL HISTORY M1290 M1291 M1292 M1293 M1294 M1295 M1296 M1297 M1298 M1299 Hall F Down-Regulation of Interferon-Stimulated Genes in Cells Harboring Hepatitis C Virus Replication Yasuhiro Itsui Cytochrome 2C19: A New Hepatic Target of Immune Reactions After Orthotopic Liver Transplantation Maria Grazia Clemente, Pietro Vajro, Maria P. Musu, Claudia Mandato, Nicolina di Cosmo, Patnzia Porqueddu, Lucia Cicotto, Lucia Zancan, Bruno Gridelli, Stefano De Virgiliis Disease Related Worries and Comorbidities and Not the Severity of the Liver Disease Determine Health Related Quality of Life in Patients with Chronic Hepatitis C Peter J. E. Schiedermaier, Winfried Haueser, Daniel Grandt Long-Term Monitoring of Platelet Counts after Interferon (IFN) Therapy, as a Non-Invasive Maker of Hepatic Fibrosis Progression and/or Regression in Patients with Chronic Hepatitis C Hideaki Taniguchi, Akiko Fujiwara, Kohsaku Sakaguchi, Yoshiaki lwasakt, Akio Moriya, Fumi Umeoka, Piao Cheng Yu, Shin-ichi Fujioka, Hiroyuki Shimomura, Yasushi Shiratori Prevalence of Hepatitis C Virus Infection in B-cell Non- Hodgkin's Lymphoma. Systematic Review and Metaanalysis Javier P. Gisbert, L. Garcia-Buey, J. M. Pajares, R. Moreno- Otero The APRI Index Is a Good Predictor of Hepatic Fibrosis, and May Be Affected by Liver Biopsy Size Ned Snyder, Leka Gajula, James J. Grady, Bruce A. Luxon. Dary] Lau, Shu-Yuan?,~iao, Roger D Soloway, ]ohn Pcter~cll Rantes Levels Correlate the Severity of Histological Inflamation in Chronic Hepatitis C Manuela G. Neuman, Jean Pierre Benhamou, Patrick Marcellin, Hemda Schmilovitz-Weis~, Ziv Ben-Ari, Marc Bourliere, Christian Trepo A Comparison Between Creatinine-Modified Child- Turcotte-Pugh Score and MELD Score in the Short-term Prognostic Assessment of Patients with Liver Cirrhosis Edoardo Giannini, Federica Botta, Federica Malfatti, Alessandra Fumagalli, Emanuela Tcb~a, Simonc Po[cgJlo, Elena Podesta, Tiziana Cotellesaa, Roberto Testa Polymorphisms of Interleukin 1 ~ and 133-Adrenergic Receptor in Japanese Patients with Nonalcoholic Steatohepatitis Yasuko Nozaki, Toshiji Saibara, Yoshihisa Nemoto, Masafumi Ono, Chikako Namikawa, Naoaki Akisawa, Shinji Iwasaki, Yoshihiro Hayashi, Makoto Hiroi, Hideaki Enzan, Saburo Onishi Quantitative Estimation of Non-Alcoholic Fatty Liver Disease as a Screening for Coronary Heart Disease Masahide Hamaguchi II, Takao Kojima, Tomomichi Matsushita, Shin Shimazaki, Takahiro Kato, Junichi Okuda, Kazunori Ida... t Denotes DDW Poster of Distinction P-167

57 POSTER SESSIONS--CLINICAL SCIENCE M1300 Natural History of Chronic Hepatitis C (HCV) in Patients with Intermittently Abnormal Aminotransferase (ALT) Levels Sophie Herve, Odile Goria, Ghassan Riachi, Eric Lerebours AM-5:00 PM Hall F M1301 IL-10 and TGE-[~I in Anti-HCV Positive Haemodialysed Patients Masier Annalisa, Di Leo Enza, Morisco Filomena, Marchini Francesco, Cecchetto Attilio, Rigotti Paolo, Maria Cristina D'Aloiso, Naccarato Remo, Burra Patrizia Sponsored by: Clinical Practice EPIDEMIOLOG M1302 M1303 Influences on Quality of Life in Patients with Hepatitis C Sara Olson, Nancy Lau, Maya Gambarin-Gelwan, Shelby Samuel, Temima Markovits, Sandy Iyer, Christine De La Cruz, Orry Erez, Robert Kurtz Separate Analysis of Asialoglycoprotein Receptors in the Right and Left Hepatic Lobes of Patients with Chronic Viral Hepatitis Using 99mTc-GSA SPECT Kazuhiko Sugahara, Hitoshi Togashi, Tohru Adachi, Junitsu lto, Hisayoshi Watanabe, Takafumi Saito, Sumio Kawata Fibrosis Progression Rate in HBe Antigen Positive Patients Is Higher by 2.5 Folds As Compared with Chronic Hepatitis C (CHC) Patients Akiko Fujiwara, Kohsaku Sakaguchi, Shin-Ichi Fujioka, Yoshiaki Iwasaki, Hideaki Taniguchi, Yasuhiro Miyake, Ryo Terada, Akio Moriya, Cheug Yu Piao, Yasushi Sbiratori M1313 M1314 Is Improved Accuracy of Reporting an Explanation for the Increasing Incidence Of Junctional Adenocarcinoma? Nikhil Misra, Leigh Roberts, Richard H. Hardwick Barrett's Esophagus Is Rare in the Swedish General Population Despite a High Prevalence of GERD: A Random Population Based Study (Kalixanda) Jukka Ronkainen, Pertti Aro, Tom Storskrubb, Sven-Erik Johansson, Elisabeth Bolling-Sternevald, Tore Lind, Hans Graffner, Michael Vieth, Manfred Stoke, Lars Engstrand, Nicholas J. Talley, Lars Agreus M O N D A Y MAY 17 M1304 M1305 M1306 M1307 M1308 M1309 M1310 M1311 M1312 Prospective Study of Predictors of Appearance. or Disappearance of Non-Alcoholic Fatty Liver Disease Masahide Harnaguchi, Takao Kojima, Tomomichi Matsushita, Shin Shimazaki, Takahiro Kato, Junichi Okuda, Kazunori Ida Serum Cytochrome C Level Reflects Liver Cell Death in Patients with Liver Diseases Akio Moriya, Yoshiaki Iwasaki, Hideaki Taniguchi, Shin- Ichi Fujioka, Hiroyuki Shimomura, Kohsaku Sakaguchi, Yasushi Shiratori Prevalence and Causes of Elevated ALT Levels Among Iranian Healthy Blood Donors Akram Porshams, Reza Malekzadeh, Mohamad R. Akbari, Shahin Merat Helicobacter bilis Associated Hepatitis in Outbred Mice James Fox, Arlin Rogers, Mark Whary, Nancy Taylor, Shilu Xu, Yan Feng, Susan Keys Validation of the Simultaneous 13C-Octanoic Acid and ~3C-Lactose Ureide Breath Test for Determination of Gastric Emptying and Orocecal Transit Time by Scintigraphy Hiroshi Kaneko, Hiroshi Imamura, Toshihiro Konagaya, Toshihiko Hayakawa, Shinichi Kakumu MCP-1 Gene Polymorphism in Chronic Hepatitis C Virus (HCV) Infection Juergen Glas, Helga-Paula Toeroek, Laurian Tonenchi, Christian Folwaczny High-Risk Sexual Behavior and the Risk for Acquiring Hepatitis C Bashar M. Attar, Arthur T. Evans, Mary Jo Atten, Brendan M. Reilly Prediction of HCV-related Fibrosis and Inflammation Based on a Constructed Model Bashar M. Attar, Gonzalo Pandolfi, Franjo Vladic, Erick Chinga-Alayo, Amfla Orucevic, Mary Jo Atten, Arthur T. Evans, Brendan M. Reilly M1315 M1316 M1317 M1318 M1319 M1320 M1321 M1322 M1323 M1324 M1325 Incidence of Adenocarcinoma in Short and Long Segment Columnar-Lined Oesophagus Piers A. C. Gatenby, James R. Ramus, Christine P. J. Caygill, Anthony Watson Barrett's Esophagus Develops During Youth or When We Are Born - Not During Adulthood. Part 5 in a Seri~s: The Origins of GERD Stephen J. Sontag, Jack Leya, Thomas Schnell, Greg Chejfec Blacks and Hispanics Have Significantly Fewer and Smaller Hiatal Hernias Than Whites. Part 1 in a Series: The Origins of GERD Stephen J. Sontag, Thomas Schnell, Jack Leya Low Incidence of Cancer in Patients with High Grade Dysplasia in Barrett's Esophagus Chel/iah R. Selvasekar, Sally Thorpe, Marco R. Novelli, Stephen G. Bown, Laurence B. Lovat The Development and Validation of the Chest Pain Questionnaire (CPQ) for Non-Cardiac Chest Pain (NCCP) Guy D. Eslick, Nicholas J. Talley Discriminating Non-Cardiac Chest Pain (NCCP) in Patients with Acute Chest Pain Presenting to an Emergency Department Guy D. Eslick, Nicholas J. Talley The Natural History of Non-cardiac Chest Pain (NCCP): A Four-Year Prospective Cohort Study Guy D. Eslick, Nicholas J. Talley IBS, Gallstones and Cholecystectomy: Association or Confounding Nicholas J. Talley, G. Richard Locke III, Hiedi M. Treitline, Patrick H. Griffin, Cathy D. Schleck, Alan R. Zinsmeister Gastro-Esophageal Reflux Disease: The New Epidemic in Developing Countries Reza Malekzadeh, Akram Pourshams, Siavosh NasseriMoghaddam, Mohamad H. Derakhshan The Impact of the Severity of Pyrosis and Regurgitation on Quality of Sleep (QOS) in Patients with Esophagitis Andre Elewaut, Paul Mainguet, Johan Imschoot High Incidence of Prescription of Drugs with Potential Interaction with Proton Pump Inhibitors in Patients with Esophagitis Andre Elewaut, Johan Imschoot P Denotes DDW Poster of Distinction

58 r POSTER SESSIONSmCLINICAL SCIENCE M1326 M1327 M1328 M1329 M1330 M1331 M M1333 M1334 M1335 M1336 M1337 M1338 M1339 M1340 Epidemiology of Gastro-Esophageal Reflux Disease Symptoms and Endoscopic Findings in the General Population Rocco M. Zagari, Cristina Martuzzi, Lorenzo Fuccio, Luigi Ricciardiello, Stefania Maltoni, Marco Di Marco, Enrico Roda, Franco Bazzoli Gastroesophageal Reflux Disease (GERD) in the French Population: Results of an Observational Survey Performed in a Sample of Nearly 8000 Subjects of 18 Years of Age and Above Jean-Francois Bretague, Bruno Richard-Molard, Charles Honnorat, Agnes Caekaert, Philippe Barthelemy Convent Seclusion and Helicobacter pylon (HP) Infection Rate Wladyslaw Bielanski, Malgorzata Plonka, Marta Czesnikiewicz, Maria J. Dobrzanska, Anna Kaminska, Urszula Szczyrk, Teresa Pawlik, Stanislaw J. Konturek Helicobacter Pylori Infection and Chronic Corpus Gastritis Related in Gastro-Esofageal Reflux Disease Rocco Zagari, Silvia Casanova, Cristina Martuzzi, Lorenzo Fuccio, Marco Di Marco, Stefania Maltoni, Luigi Ricciardiello, Antouia D'Errico, Walter Grigioni, Roberto Fiocca, Enrico Roda, Franco Bazzoli An Evidence-Based Examination of the African Enigma in Relation to Helicobacter pylori Infection Aamer Agha, David Y. Graham Infection Rate of Helicobacter pylori in Korean Adults Nayoung Kim, Seon Hee Lim, Kye Heui Lee, Jung Mogg Kim, Jin-Hyeok Hwang, Jin-Wook Kim, Dong Ho Lee, Hyun Chae Jung, In Sung Song Does Risk of NSAID-Related Ulcer Complications Reduce Over Time? Delia Schaffer, Craig Eagle, Ian Marshner, Mendel Grobler, Gurkirpal Singh, Chris Fenn, Manjula Schou, Kathleen Cumow Psychological Factors Mediate the Association Between Low Social Class and Upper Gastrointestinal (GI) Complaints in Australian Adults Stuart Howell, Susan Quine, Nicholas J. Talley Defecation Disorders: A French Population Survey kaurent Siproudhis, Olivia Morio, ke Grep Changing Patterns of Gallbladder Cancer in New Mexico Jehad Barakat, Thomas Y. Ma Adult Irritable Bowel Syndrome (IBS) Is Linked to the Childhood Socio-economic Environment Stuart Howell, Nicholas J. Talley, Susan Quine, Richie Poulton Prevalence of Continuous Upper and Lower GI Symptoms in Diabetics and Matched Controls Peter L. Beyer, Richard McCallum Irritable Bowel Syndrome Benchmarks: An Episodic, Claims-Based, Patient-Centric View Michael W. Pill Prevalence and Impact of Upper and Lower Gastrointestinal (GI) Symptoms in the Greek General Population George Papatheodoridis, Demetrios Karamanolis The Development and Validation of the Gastrointestinal Symptom Checklist (GISC) Stuart Howell, Nicholas J. Talley, Susan Quine M1341 M1342 M1343 M1344 M1345 M1346 M1347 M1348 M M1350 M1351 M1352 M1353 M1354 Hidden Bias in Clinical Studies of the Gastrointestinal (GI) Tract: Presentation Patterns Influence the Results in Studies of Patient Samples Stuart Howell, Susan Quine, Nicholas J. Talley Epidemiological Analysis of 486 Patients with Irritable Bowel Syndrome (IBS) in Japan: From the Data of 28,000 Consecutive Non-Referral Outpatients at the General Internal Medicine in an Urban Hospital ( ). M Ryosuke Shoda Genomic DNA from Buccal Swabs Recruited by Regular Mail in a Dutch Pancreatitis Cohort Study B. W. Marcel Spanier, Jitteke van der Meij, Elsemieke M. Gimpel, Esther W. M. Vogels, Pieter H. Reitsma, Sander J. Van Deventer, Marco J. Bruno Epidemiology of Malignant Cystic Neoplasms of the Pancreas Gregory H. Nguyenduc, Ronald Schrader, Charles Key, Gulshan Parasher Variation in Gastric Cancer Incidence and Survival Trends with Deprivation over Fifteen Years: A Population Based Study Subhajit Dutta Roy, Abdullah Jibawi, Mark Deakin, David Corless Observational Study of Chronic Pancreatitis Incidence and Prevalence and Its Complications in France Francois Dyard, Philippe Levy, Marc Barthet, Michel Amouretti, Bruno Richard-Molard, Anne-Marie Marion- Audibert Serum Selenium in Different Iranian Populations with Different Rates of Upper Gastrointestinal (UGI) Cancer Incidences Mehdi Nouraie, Akram Pourshams, Farin Kamangar, Masoud Sotoudeh, Mohammad Hossein Derakhshan, Mohammad Reza Akbari, Christian Abnet, Philip Taylor, Reza Malekzadeh, Sanford Dawsey An Association Between Fatty Hver and Breast Cancer Among Japanese Women: A case-control study Takero Mazaki, Kazuyuki Tomioka, Yosuke Suenaga, Yosuke Takeya Vitamin B12 Levels and Recurrence of Colorectal Adenomas Jeffrey T. Wet, keila A. M<t, John A Baron. Robert 5. Sandier Gastrointestinal Stromal Tumor (GIST) Incidence in the US Population James L. Lin, Namgyal L. Kyulo, John G. Lc~" Time Trends in Stomach Cancer Incidence and Mortality in Call, Colombia Throughout : An Age-Period-Cohort Analysis Luis E. Bravo, Paola Pisani, Edwin Carra~cal, Max Parl:in. Pelayo Correa Hepatitis C Infection and the Rising Incidence of Hepatocellnlar Carcinoma: A Population-Based Study Jessica A. Davila, Robert O. Morgan, Yasser Shaib, Katherine A. McGlynn, Hashem B. El-Serag Glucagonomas, VIPomas and Somatostatinomas in Multiple Endocrine Neoplasia Type 1 Nathalie Lew-Bohbot, Corinne Merle, Pierre Goudet, Brigitte Delemer, Alain Calender, Damien Jolly, Gerard Thiefin, Guillaume Cadiot Prevalence of CYP2C19 Polymorphism in a Mexican population Kduardo Giasi Gonzalez, Elvira Garza Gonzalez, Hector J.J. Maldonado-Garza, Francisco J. Bosques Padilla Denotes DDW Poster of Distinction P-169

59 POSTER SESSIONSmCLINICAL SCIENCE M1355 M1356 Mothers of Crohn's Disease Patients Show a Higher Prevalence of Breast Cancer Than Those of Controls. An IG-IBD Study Gabriele Riegler, Luigi Caserta, Fabiana Castiglione, Daniela Valpiani, Giovanni Lombardi, Ilaria Esposito, Annalisa di Leone, Sabrina Giaquinto, Antonio Rispo, Giorgio Zoli, Paolo Gionchetti, Angelo Viscido, Giacomo Sturniolo Relationship Between Environmental Factors and Inflammatory Bowel Disease Claudia Cucino, Mara Fasani, Silvano Gallus, Giovanni Maconi, Sandro Ardizzone, Gabriele Bianchi Porro M M1367 A Standardized Test Meal Increases the Sensitivity of 24 Hour ph Monitoring for the Diagnosis of Early Gastroesophageal Reflux Disease (GERD) Rodney J. Mason, Farzaneh Banki, Giuseppe Portale, Jeffrey A. Hagen, Jeffrey H. Peters, Steve R. DeMeester, Cedric G. Bremner, Tom R. DeMeester Short-Term Treatment with Proton Pump Inhibitors As a Test for Gastroesophageal Reflux Disease: A Meta- Analysis of Diagnostic Test Characteristics Mattijs E. Numans, Joseph Lau, Nick J. de Wit, Peter A. Bonis M1357 Are Children's Complementary Therapy utilization Patterns the Same as Those of Adults for Treatment of Inflammatory Bowel Disease? Lana S. Trojan, Robert J. Hilsden, Marja J. Verhoef, Anthony R. Otley M1368 Bravo Capsule Placement in the Cardia: A Novel Method for Analysis of Proximal Stomach Acid Environment Mitchal A. Schreiner, Peter J. Kahrilas, Ikuo Hirano, Thomas J. Lee, John E. Pandolfino M1358 The Epidemiology of Inflammatory Bowel Disease in Children and Young Adults in Israel: A Population Based Study Eran Israeli, Yehudith Mish, Eran Goldin, Ran Balicer, Itamar Grotto M1369 Impedance Signature of Pharyngeal Gaseous Reflux Recorded During 24-Hr Pharyngoesophageal Ambulatory Impedance Monitoring Osamu Kawamura, Muhammad Aslam, Candy Hofmann, Tanya J. Rittmann, Reza Shaker M1359 How Unbelievable Celiac Disease Is Unrecognised in Pembrokeshire: A 5-Year Hospital Population-Based Study Kamran Rostami M1370 Acid Perfusion Test: A Useful Test for Evaluating Esophageal Acid Sensitivity Alistair L. King, Angela Anggiansah, Roy Anggiansah, Terry Wong M O N D A Y MAY 17 M1360 M1361 Prevalence of Osteoporosis Risk Factors in a Tertiary Outpatient GI Clinic Paul Evans, Michelle T. Thirty, Robert S. Sandier, Lisa M. Gangarosa Re-Evaluation of Chlamydia Trachomatis Infection As a Gastrointestinal Illness Masami Yoshiike, Hitoshi Nakajima, Terimi Kamisawa, Naoto Egawa AM-5:00 PM Hall F Sponsored by: Esophageal, Gastric and Duodenal Disorders GERD DIAGNOSIS M1362 M M1364 MI365 Correlation of Abdominal Ultrasonographic Findings with Continuous 24-Hour ph Monitoring Oesophageal Studies in Children with Gastroesphageal Reflux Disease (GORD) Nermeen Gala1, Sonny K. F. Chong, Val Cook, Mary Warren Simultaneous Recordings of Esophageal Acid Exposure Using Conventional ph Monitoring and the Bravo Telemetric Catheter-Free System : Analysis of Concordance Stanislas Bruley des Varannes, Francois Mion, Philippe Ducrotte, Frank Zerbib, Philippe Denis, Thierry Ponchon, Jean-Paul Galmiche EER Related Laryngeal Signs and Symptoms in Patients with Heartburn Riitta H. Ylitalo, Per-Ake Lindestad, Stellan Hertegard ReQuestTM: International Validation of a New Evaluative Symptom-scale in Patients with Endoscopic Negative Gastroesophageal Reflux Disease (engerd) Kama Dev Bardhan, Vincenzo Stanghellini, David Armstrong, Peter Berghoefer, Gudrun Gatz, Hubert Moennikes M1371 M1372 M1373 M1374 M1375 M1376 M1377 M1378 Reflux Through an Ultrasonographic Eye: Measuring Esophageal Distension During Spontaneous Gastroesophageal Reflux Episodes Neelesh A. Tipnis, Yash R. Mittal, Jaimin Liu, Vikas Bhalla, James Puckett, Ravinder K. Mittal Simultaneous Esophageal ph Recording with the BRAVO System and a Standard Probe-Based Device Mauro Bortolotti, Luigi Gatta, Nimish Vakil, Chiara Ricci, Andrea Tampieri, Matteo Giovannini, Mario Miglioli, Dino Vaira Histological Changes in Esophageal Mucosa: Correlation with Ambulatory 24 hour ph Monitoring in Pediatric Patients Alexandra P. Eidelwein, Harrison P. Dilworth, Ryan S. Carvalho, Carmen Cuffan A New And Direct Method To Assess Esophago-Gastric Junction (EGJ) Function Barry P. McMahon, Jens B. Frokjaer, Asbjorn M. Drewes, Hans Gregersen Abnormal Gastroesophageal Flap Valve is Not Sensitive Enough to Separate Low Grade Erosive Esophagitis from Normal Population Bor-Ru Lin, Chien-Chung Liao, Jau-Min Wong, Jyh-Chin Yang, Jin-Town Wang, Teh-Hong Wang Extended ph Monitoring with the Bravo Capsule Increases Diagnostic Yield in Chest Pain Patients Chandra Prakash, Ray E. Clouse MIB-1 Proliferation Index of Squamous Epithelium in Gastroesophageal Reflux Disease. Correlations with Clinical, Endoscopic and Morphological Data Roberto Fiocca, Luca Mastracci, Paola Spaggiari, Patrizia Zentilin, Paola Ceppa, Pietro Dulbecco, Carlo Mansi, Vincenzo Savarino Detection of Proximal Esophageal Acid Exposure Enhances Sensitivity of PH Test in Non Erosive Gastroesophageal Reflux Disease Patients Sara Emerenziani, Mentore Ribolsi, Michele P. L. Guarino, Renato Caviglia, Simone Carotti, Tommasangelo Petitti, Michele Cicala P-170 ~ Denotes DDW Poster of Distinction

60 v POSTER SESSIONS~CLINICAL SCIENCE M1379 M1380 M1381 M1382 M1383 M1384 M1385 M1386 M1387 M1388 M1389 M1390 M1391 M1392 Optimal Impedance Monitoring Technique for Minute and Small Pharyngeal Reflux Events Muhammad Aslam, Caryn Easterling, Osamu Kawamura, Tanya Rittmann, Candy Hofmann, Jianxiang Liu, Reza Shaker Can Multichannel Intraluminal Impedance (MII) Help to Explain Reflux Symptoms in Patients When ph Test Fails? Dipankar Mukherjee, Etsuro Yazaki, David F. Evans, Sritharan S. Kadirkamanathan Determination of a Conversion Factor To Permit Accurate Transoral Placement of the BRAVO ph Capsule Following Transnasal Manometry Tracia L. O'Shana, Mary L. Hynes, Richard I. Rothstein Acid Not Volume Predict Symptoms of Reflux in Untreated GERD Patients James L. Wise, Joseph A. Murray, Ross A. Dierkhising, Alan R. Zinsmeister Comparison of a Simple Questionnaire to Locke Questionnaire in the Evaluation of GERD Symptoms Jasmohan S. Bajaj, Kevin Kao, Kia Saeian Prevalence of Symptomatic GERD in Patients with Uninvestigated Excessive Daytime Sleepiness Nalini M. Guda, Helen H. Lantz, Susan Partington, Maqbool Arshad, Gary Leo, Nimish B. Vakil Comparison of Reflux-Associated Symptom Probability (RASP) Tests from Ambulatory ph Monitoring Clinton T. Snedegar, Ray E. Clouse Reliability of Esophageal Balloon Distention and Bernstein Measurements in Patients with Functional Heartburn Sheila Rodriguez-Stanley, Sattar Zubaidi, Howard Proskin, Philip B. Miner Jr. Is Short Post-prandial Esophageal ph Monitoring Sufficient To Diagnose Reflux? Amine Hila, Amit Agrawal, Janice Freeman, Shirley Jamison, Donald O. Castell Validation of the Short-Form Reflux-Qual (RQS) : A Gastro-Oesophageal Reflux Disease (GERD) Specific Quality of Life Questionnaire Developed for Standard Medical Practice Michel Amouretti, Bernard Nallet, Michel Robaszkiewicz, Jean-Pierre Wainsten, Christine de La Loge, Khadra Benmedjahed, Bernard Schatz, Sylvie Brin Risk Factors for Erosive Esophagitis in Patients Undergoing Endoscopy for the Evaluation of GERD Elena Sidorenko, Allan P. Weston, Matthew Hall, April Higbee, Prateek Sharma ph Monitoring in Tracheal Stenosis: Is There a Relationship Between Stenosis and Acid Reflux? Kathryn A. Peterson III, Christopher Canale II, John Fang, Marshall Smith, Mark Elstad Comparative Effect of PPI (Proton Pump Inhibitor) Test with Rabeprazole, Lansoprazole, and Omeprazole: Role of Endoscopic Finding and H.Pylori Infection Hiroki Ichimura, Hironobu Takada, Shigeki Oka, Hiroshi Takada, Morio Takahashi, Hajime Kuwayama Twenty-four Hour Impedance and ph Monitoring (24-hr Imp-pH) in the Evaluation of GERD Patients with Persistent Symptoms Despite bid Proton Pump Inhibitors (PPI): A Muhicenter Study Steven Shay, Radu Tutuian, Daniel Sifrim, Marcelo Vela, Xin Zhang, Donald Castell M1393 M1394 M1395 M1396 M1397 M1398 A Three-Component Clinical Model To Predict Reflux- Related Histopathology Fritz Francois, Edmund J. Bini, Guillermo 1. Perez-Perez, Herman T. Yee, Martin J. Blaser Correlation Between Clinical Symptoms and Endoscopic Findings in Reflux Esophagitis: Evaluation in 8,031 Adult Subjects Masatoki Adachi, Akifumi Ootani, Kazuyo Okamoto, Akiko Danjo, Hiroyuki Sakata, Seiji Tsunada, Ryuichi lwakiri, Kazuma Fujimoto Twenty-four Hour Ambulatory Impedance and ph Monitoring (24h Imp-pH) in the Detection of Gas-only Reflux Francisco Marrero, Steven Shay Symptom Perception with Minimal Changes on Esophageal ph in Patients with Non-erosive Gastroesophageal Reflux Disease (NERD) Jose M. Remes-Troche, Ramon Carmona-Sanchez, Octavio Gomez-Escudero, Max J. Schmulson, Miguel A. Valdovinos Ingestion of Acid Foods Mimics Gastroesophageal Reflux During Ambulatory ph Monitoring Amit Agrawal, Amine Hila, Janice Freeman, Donald O. Castell Natural History of Gastroesophageal Reflux in General Practice: A Retrospective Cohort Study of Incidence and Risk Factors Aria Ruigomez, Luts A. Garcia Rodriguez, Marl-Ann Wallander, Saga Johansson, Hans Graffner, John Dent AM-5:00 PM Hall F ~ Sponsored by: Esophageal, Gastric and Duodenal Disorders GERD EPIDEMIOLOGY AND MANAGEMENT Clinical Predictors of Medical Visits in Subjects with M1399 Gastroesophageal Reflux Symptoms. A Population-Based Study Jorge A. Olmos, Juan C. Chiocca, Roberto ltiga. Hcclor Rios, Luis Soifer, Graciela Salis, Jorge Davoios The Effects of Gastroesophageal Reflux on Sleep M1400 Parameters in Patients with Insomnia Anthony J. DiMarino, Kuldip S. Banwait, Kric Kschill<el Alison Schneider, Andra Greenberg, Michad DiMarino. Karl Doghramji, Sidney Cohen Obesity Does Not Influence Symptom Profile in Patients M1401 with Gastropharyngeal Reflux Steven P. Harrell, Jennifer Koopman, Wdby "Wmstc:~d. Erk Lentsch, John M. Wo Obstructive Sleep Apnea (OSA) ls Improved by a M1402 Prolonged Treatment of Gastroesophageal Reflux (GER) with Omeprazole Mauro Bortolotti, Matteo Giovannini, Mario Miglioli Long-term Follow-up of Patients Treated with Acid M1403 Suppressive Therapy for Suspected Reflux Related Laryngeal Signs and Symptoms Jason M. Swoger, Farah Khandwala, Douglas Hicks, Joel Richter, Michael F. Vaezi Traditional Lifestyle Behaviors Attributed to Heartburn M1404 Are Not Associated with Gastropharyngeal Reflux Steven P. Harrell, Michael Tzagournis, Jennifer Koopman, Welby Winstead, Eric Lentsch, Tim Aldrich, Gerald Dryden, John M Wo Denotes DDW Poster of Distinction P-171

61 POSTER SESSIONSmCLINICAL SCIENCE M1405 Is There any Relationship Between Morbid Obesity and Gastroesophageal Reflux Disease (GERD)? Vicente Ortiz, Julio Ponce, Beatriz Martinez, Alberto Fernandez Villaverde, Marta Ponce, Belch Beltran, Nuria Maroto, Vicente Garrigues M1419 Screening for Barrett's Esophagus (BE) in Supraesophageal Reflux Disease (SRD) Is Not Indicated Mitchell D. Weinberg, David A. Katzka, Mark G. Weiner, David C. Metz M1406 Two Weeks of Rabeprazole (RAB) Treatment Is As Effective As 4 Weeks for Long Term Management of Gastroesophageal Reflux Disease (GERD) Arsene Papazian, Stanislas Bruley des Varannes, Jacques Corallo, Philippe Houcke, Jean-Paul Jacques, Patrick Levy, Jean Francois Rey, Fernand Vicari, Elisabeth Tocque, Sylvie Bonnot-Marlier Prevalence and Risk Factors for Gastro-oesophageal Reflux Symptoms (GORS) in a Danish Population - Quality of Life and Use of Health Care Resources Mette Wildner-Christensen, Jane M. Hansen, Ove B. Schaffalitzky de Muckadell AM-5:00 PM Hall F Sponsored by: Esophageal, Gastric and Duodenal Disorders M O N D A Y MAY 17 M1407 M1408 M1409 M1410 M1411 M1412 M1413 M1414 M1415 M1416 M1417 M1418 GERD and Obesity. Pathophysiology and Implications for Therapy Maria V. Gorodner, Carlos A. Galvani, Karen BagateIos, James W. Ostroff, Marco G. Patti Can Gastroesophageal Reflux Influence Outcomes After Lung Transplantation? Christopher Canale, Barbara Cahill, Carrie Sullivan, Kathryn A. Peterson III Risk Factors for Gastro-Oesophageal Reflux Symptoms: A Community Study Imtiyaz Mohammed, Peter Nightingale, Nigel TrudgilI Gastroesophageal Reflux (GER) During Siesta Cirilo Amoros Sr., Vicente Sanchiz, Lidia Marti, Vicent Hernandez, Belch Herreros, Miguel Minguez, Amaya Basagoiti, Francisco Mora, Adolfo Benages Epidemiological Evaluation of Gastroesophageal Reflux Disease (GERD)-Associated Symptoms in Healthy Subjects Vincenzo Stanghellini, David Armstrong, Hubert Moennikes, Peter Berghoefer, Gudrun Gatz, Kama Dev Bardhan Prevalence of Gastro-Oesophageal Reflux Disease (GERD) and Manometric Oesophageal Finding in Patients with Morbid Obesity Selected for Bariatric Surgery. A Prospective Study in 100 Patients Mobamed Merrouche, Florence Hamois, Jean Marc Sabate, Simon Msika, Benoit Coffin A Prospective Study of the Prevalence, Severity and Risk Factors for GERD in Pregnancy Dia Simmons, Naresh T. Gunaratnam, Chiquita Berg, Ruth Churley-Strom, James L. Marley Effect of Rabeprazole on Post-Menopausal Osteoporosis in Patients with Gastro-EsophageaI Reflux Disease (GERD) Hironobu Takada, Junko Takahashi, Kuzutomo Suzuki, Hajime Kuwayama, Yoshinobu Hamada, Takeyoshi Ohkura Pantoprazole 20 mg Is Superior to Esomeprazole 20 mg for Symptom Relief in Endoscopy Negative (En)GERD Patients with Highly Fluctuating Symptoms Hubert Moennikes, Bemd Pfaffenberger, Gudrun Gatz Gastro-Esophageal Reflux Disease (GERD): A Comparison of Lansoprazole (Lan) and Pantorpazole (Pan) in General Practice Werner Dohmen Night Time Heartburn Prevalence and Impact: A Telephone Survey Pali Hungin GERD: NONPHARMACOLOGICAL THERAPY Endoscopic Plication (Endocinch) Repairs a Physiologic M1420 Defect in Patients with Gastroesophageal Reflux Disease (GERD): Absent Pressure Profile Due to the Gastric Sling Fibers Larry S. Miller, Qing Dai, John Dimitriou, Bryan Schiffer, James Brasseur Endoscopic Gastroplication (EndoCinch TM) as M1421 Alternative Option in Treatment of GERD - an 18- months Follow Up Alexander Zabel-Langhennig, Ingolf Schiefke, Susanne Neumann, Felix Gundling, Juergen Feisthammel, Joachim Moessner, Karel Caca Effect,of Radiofrequency Energy Therapy on Reflux M1422 Mechanisms and Vagus Nerve Function in Patients with GERD Jelle Haringsma, Ad A. M. Masclee, Carlien de Jong, Ernst J. Kuipers Laparoscopic Fundoplication: Is It Worthwile in M1423 Patients with Persistent Gastro-Esophageal Reflux Disease (GERD) Symptoms Despite Proton Pump Inhibitors (PPI) Therapy Alfonso Torquati, Rami Lutfi, Joan Kaiser, William Richards Gastric Pacing Affects Lower Esophageal Sphincter M1424 Pressure and Is Beneficial on GERD in Morbidly Obese Patients Claudia Knippig, Jochin Weigt, Stefanie Wolff, Sabine Westphal, Hans Lippert, Peter Malfertheiner Therapeutic Potential of Gastric Electrical Stimulation M1425 for Gastroesophageal Reflux: A Preliminary Canine Study Jinhong Xing, Hongbing Zhu, Jiande Chen Poor Esophageal Emptying Post Fundoplication Is M1426 Explained by Deficient Muscle Tone in the Distal Esophagus James G. Brasseur, Peter J. Kahrilas, John E. Pandolfino, Tamer Zaki, Raymond J. Joehl, Sudip K. Ghosh Predictors of Long-Term Success of Endoscopic M1427 Treatment for Gastroesophageal Reflux Disease Julia J. Liu, John Saltzman, Rie Ookubo, David L. Cart- Locke Enteryx : 24-Month Clinical Safety and Effectiveness M1428 David A. Johnson, James Aisenberg, Lawrence B. Cohen, Robert A. Ganz, Glen A. Lehman, T. Raymond Foley Evaluation of Endoscopic Full-Thickness Plication on M1429 Anti-Reflux Valve Competency James P. Dolan, Brett C. Sheppard, John G. Hunter M1430 Is a Functional Study of the Esophagus at 3 and 12 Months Necessary After a Nissen Procedure? Cirilo Amoros Sr., Vicente Sanchiz, Marta M. Bosca, Vicent Hemandez, Joan Tosca, Belch Herreros, Miguel Minguez, Francisco Mora, Adolfo Benages P-172 ~ Denotes DDW Poster of Distinction

62 POSTER SESSIONS--CLINICAL SCIENCE M1431 M1432 M1433 M1434 M1435 Postfundoplication Dysphagia: Relation Between Resting and Residual Pressure of the Lower Esophageal Sphincter (LES) Cirilo Amoros Sr., Vicente Sanchiz, Maria M. Bosca, Vicent Hernandez, Lidia Marti, Belch Herreros, Miguel Minguez, Francisco Mora, Adolfo Benages Significant Weight Loss After Laparoscopic Nissen Fundoplication Christoph Neumayer, Ruxandra Ciovica, Georg Erd, Silke Leidl, Stephan Lehr, Michael Gadenstaetter, Gerhard Schwab Biliary Reflux in Gastrectomized Patients: Treatment by Ethylene-Vinyl-Alcohol Polymer (Enteryx) Injection Laugier Rene, Deviere Jacques, Costamagna Guido, Letard Jean Claude, Andrea Tringali, Grandval Philippe Percutaneous Endoscopic Gastrostomy Jejunostomy Tubes (PEG-J) in Children: A 9- Year Hospital Based Data-Base Analysis John E. Fortunate, Anti Darbari, Sally Mitchell, Carmen Cuffari Anti-Reflux Surgery Outcomes in Pediatric Gastroesophageal Reflux Disease (GERD) Diego M. Diaz, Troy E. Gibbons, Kurt Heiss, Mark L. Wulkan, Richard R. Ricketts, Benjamin D. Gold AM-5:00 PM Hall F.~ ~r Sponsored by: Esophageal, Gastric and Duodenal Disorders GERD: PHARMACOLOGICAL THERAPY Mechanism of Action of AZD0865, an H+,K+-ATPase M1436 Selective, Potassium-Competitive Acid Blocker Carin Briving, Karin Svensson, lngela Maxvall, Kjell Andersson AZD A New Potassium-Competitive Acid M1437 Blocker - Exhibits Maximal Gastric Antisecretory Effects from First Dose Bjom Holstein, Agneta Holmberg, Malin Florentzson, Ann Aurell Holmberg, Magdalena Andersson, Kjell Andersson Effect of Omeprazole on Symptoms and Uhrast}uctural M1438 Esophageal Damage in Duodenogastroesophageal Reflux (DGER) Calabrese Carlo, Fabbri Anna, Bortolotti Mauro, Cenacchi Giovanna, Areni Alessandra, Scialpi Carlo, Miglioli Mario, Di Febo Giulio Co-administration of Oral Pentagastrin Enhances the M1439 Efficacy of Proton Pump Inhibitors Eytan Bardan, Lada Paul, Simon Bar Meir, Sabina Glozman, Yehuda Chowers Pharmacokinetic and Pharmacodynamic Profiles of M1440 AZD0865, a Novel, Potassium-Competitive Acid Blocker Bjorn Holstein, Agneta Holmberg, Malin Florentzson, Ann AurelI Holmberg, Magdalena Andersson, Kjell Andersson Response to Proton Pump Inhibitors in Non-Cardiac M1441 Chest Pain: A Meta-analysis Filippo Cremonini, James L. Wise, Nicholas J. Talley M1442 M1443 M1444 M1445 M1446 M1447 M1448 M1449 M1450 M1451 M1452 M1453 Early Effects of Tenatoprazole 40 mg And Esomeprazole 40 mg on Intragastric ph in Caucasian Healthy Volunteers Jean-Paul Galmiche, Stanislas Bruley des Varannes, Sylvie Sacher-Huvelin, Fabienne Vavasseur, Alain Taccoen, Paola Fiorentini, Michel Homerin Nizatidine Controlled Release (N) Has Gastric Prokinetic Effects in Patients with Gastroesophageal Reflux Disease (GERD) Richard W. McCallum, Edwin Zarling, Allen Goetsch, Carl Griffin, Irene Sarosiek, Keith Rotenberg Results of a National Education Initiative to Optimize PPI Dosing for the Treatment of Nocturnal Reflux- Induced Asthma Amongst Allergists Yuhjung J. Tsai, Naresh T. Gunaramam, James Baldwin, Eileen Robinson The Effect of Acid Suppression on Sleep Patterns and Sleep-Related Gastroesophageal Reflux William err, Jennifer Thompson, Suanne Goodrich The Effect of Proton Pump Therapy on Disturbed Sleep Mechanics Induced by Esophageal Acid Exposure Kuldip S. Banwait, Andra Greenberg, Eric Eschmger, Karl Doghramji, Sidney Cohen, Anthony J. DiMarino Jr. Nocturnal Acid Inhibition by Different Dosing Schemes of Rabeprazole in Relation to CYP2C19 Genotype Mitsushige Sugimoto, Takahisa Furuta, Naohito Shirai, Masayoshi Kajimura, Shinji Sakurai, Kyoichi Ohashi, Takashi Ishizaki Effect of Selective Vanilloid Receptor I(VR1) Antagonist JYL142 on Capsaicin and Acid-induced Activation of Vagal Afferent Fibers in the Esophagus Shachar Peles, Anders Lehmann, Bidyut K. Medda, Reza Shaker, Jyoti N. Sengupta Tenatoprazole, a Novel Proton Pump Inhibitor with a Prolonged Haff-Life. Effects of a 7-Day Dosing on Diurnal and Nocturnal Intragastric ph, and Comparison with Esomeprazole in Caucasian Healthy Volunteers Jean-Paul Galmiche, Philippe Ducrotte, Stanislas Bmley des Varannes, Sylvie Sacher-Huvelin, Fabienne Vavasseur, Alain Taccoen, Paola Fiorentini, Michel Homerin Esomeprazole for the Relief of Moderate to Severe LZ~ Nighttime Heartburn and Associated Sleep Disturbance in Patients with GERD: A Muhicenter, Randomized, 1 Double-Blind, Placebo-Controlled, 4-Week Stud}'... ~ David Johnson, William err. Assunr.a Cuccia, Ba~t)'-i la.xkt, Kurt Brown, Thomas Roth Pentadecapeptide BPC157 Combines Lower Esophageal and Pyloric Sphincter Pressure and Reflux Esophagiti~ Attenuation in Rat Igor Petrovic, Petar Drvis, h'an Dobric, Marie Kopljal- Damir Shejbal, Lovorka Batclja, Alenka Boban-Bla~aic, Neven Kokic, Ante Tonkic, Skjcpan Mi>e. Mat-io qtare~,ink. Tomislav Anic, Sven Seiwerth, Predrag Sikiric Prolonged Effect of Baclofcn on Esophageal Motility: A 48-hour Manometric Study in Healthy Subjects Laurino Grossi, Giorgio Cappello, Mariangela Spezzaferro, Leonardo Marzio Biphasic Effect of Prostaglandin E2 on Acid Reflux Esophagitis Mediated by EP1 Receptors in Rats: Relation to Pepsin Secretion Masanori Yamato, Kenji Nagahama, Shinichi Kate, Koji Takeuchi Denotes DDW Poster of Distinction P-173

63 POSTER SESSIONSmCLINICAL SCIENCE M1454 Gastroesophageal Reflux Disease (GERD) as a Cause of Death Is Increasing: Analysis of Fatal Cases Under Conservative Treatment Jarmo A. Salo, Tuomo K. Rantanen, Jari V. Rasanen, Jouko O. Isolauri, Eero I. Sihvo M1467 Esomeprazole as Compared with Other PPI's in Reflux Esophagitis: A Meta-Analysis of Randomized Controlled Trials Suryakanth R. Gurudu, Virender Sharma, Ahmed Khan, Ashish Sharma, Pankaj Singh M1455 Chewable Combination for Therapy of Gastroesophageal Reflux Disease: A Novel Approach to Treatment Robert Reddig, Irene Sarosiek, Mohammed Kabir, Katherine Roeser, Sandra Sostarich, Stanley Edlavitch, Richard McCallum, Jerzy Sarosiek Splitting the Daily Esomeprazole Dose Improves Initial Gastric Acid Control and Reduces Nocturnal Acid Breakthrough Compared to Once Daily Dosage Johann Hammer, Barbara Schmidt M1468 Famotidine 20 mg is Superior to Famotidine 10 mg in Preventing Heartburn Symptoms when Administered Prior to a Provocative Meal Scott H. Korn, Marianne Villani, Robert W. Tipping, Amy R. Replogle, Jeffrey G. Levine M O N D A Y MAY 17 M1456 M1457 M1458 M1459 M1460 M1461 M1462 M1463 M1464 M1465 Effect of Esomeprazole 40 mg BID Versus Pantoprazole 40 mg BID on Intragastric Acidity in Healthy Subjects: A Randomized Cross-over Study Stephan Miehlke, Ahmed Madisch, Franziska Lindner, Christian Kirsch, Eberhard Kuhlisch, Andrea Morgner, Joachim Labenz Esomeprazole 40 mg Heals Significantly More Helicobacter Pylori-Negative Erosive Esophagitis Patients Than Pantoprazole 40 mg Joachim Labenz, Emma Naucler, Nanna Keeling, Stefan Eklund The Influence of Cytochrome P450 2C19 Metabolizer Genotype on the Antisecretory Effects of Esomeprazole, Lansoprazole, Pantoprazole and Rabeprazole Clive H. Wilder-Smith, Daniel Schindler, Kerstin Rohss Effects of Rabeprazole on Regional Gastric Acidity and the Acid Pocket at the Cardia/Gastroesophageal Junction Lien Vo, Hrair P. Simonian, Siva Doma, Robert S. Fisher, Henry P. Parkman The Economical Impact of Six Months Management of Gastroesophageal Reflux Disease in Primary Care: Comparison Between on Demand Treatment and Treatment Courses with Esomeprazole Villy Meineche-Schmidt, Anne Hvenegaard, Henrik H. Juhl A Comparison of the Bioavailability of 15MG Lansoprazole Oro-Dispersible Tablet Dispersed in the Mouth with Prior Dispersal in Water Jorg Taubel, Ulrike Lorch, Garth Baxter A Novel Proton Pump Inhibitor Administration Option: Lansoprazole Orally Disintegrating Tablet Dispersed in Water and Administered via Nasogastric Tube James W. Freston, Brendan J. Colgan, Michael J. Kukulka, Eric Lloyd, Chang Lee The Interaction of Alcohol, Helicobacter pylori and GERD Nils Homann, Stephan Bornhardt, Diether Ludwig The Effect of Powerful Acid Suppression on Acidic and Non-Acidic Reflux During Sleep William Orr, Michael D. Hunter, Suanne Goodrich M1469 M1470 M1471 M1472 M1473 M1474 M1475 M1476 M1477 Inhibitory Effect of Rebamipide on Acute Reflux Esophagitis in Rats Kazuhiro Katada, Norimasa Yoshida, Yutaka Isozaki, Masaaki Kuroda, Kazuhiko Uchiyama, Tomohisa Takagi, Satoshi Kokura, Hiroshi Ichikawa, "fuji Naito, Takeshi Okanoue, Toshikazu Yoshikawa Effects of Rabeprazole, 20 rag, or Esomeprazole, 20 rag, on 24-h Intragastric ph in H. Pylori Positive PPI Extensive Metabolizers Vasily A. Isakov, Sergey V. Morozov, Olga M. Tsodikova, Alexander E. Guschin The Therapeutic Effects of Rabeprazole at a Dose of 10mg on Reflux Esophagitis May Not Be Influenced by CYP2C19 Polymorphism Ken Ariizumi, Shuichi Ohara, Tomoyuki Koike Sr., Masashi Kawamura, Yoshifumi Inomata, Yasushi Kitagawa, Naohiro Dairaku, Katsunori Iijima, Akira Imatani, Katsuaki Kato, Hitoshi Sekine, Tooru Shimosegawa Sleep Efficiency; Effect of PPI Therapy in Patients with Marked Sleep Disturbance Anthony J. DiMarino Jr., Kuldip S. Banwait, Eric Eschinger, Andra Greenberg, Karl Doghramji, Sidney Cohen A Randomized Open Trial for Comparison of Proton Pump Inhibitors (PPIs) for Endoscopic positive Reflux Disease (ERD) and Endoscopic Negative Reflux Disease (NERD) in Relation to Helicobacter pylori (HP) infection Hajime Kuwayama, Shigeki Oka, Hironobu Takada, Hiroki Ichimura, Morio Takahashi Incidence of Erosive Esophagitis After Short-term Discontinuation of Proton Pump Inhibitor Therapy Julia J. Liu, Veruska Di Sena, Rie Ookubo, John Saltzman Superior Clinical, Endoscopic and Histologic Efficacy and Tolerability of Pantoprazole Compared with Ranitidine and Omeprazole in Patients with Gastro- Oesophageal Reflux Disease (GORD) Roland Pulanic, Marina Premuzic, Tomislav Brkic, Milorad Opacic, Natasa Jokic-Begic OTC PPIs Unlikely To Be Used As Directed Latoya E. Bernard, Lisa Mclntyre, John M. Inadomi Intravenous Pantoprazole Is an Effective Gastric Acid Suppressant When Used Initially in Patients with Gastroesophageal Reflux Disease (GERD) Vijaya S. Pratha, Daniel L. Hogan, Richard B. Lynn, Robyn Karlstadt, Michael Burton, David C. Metz M1466 Omeprazole Long-Term Maintenance Therapy in Reflux Esophagitis (RE): Remission Rate and Adverse Drug Reaction by CYP2C19 Genotype Toshifumi Ohkusa, Takama Maekawa, Tetsuo Arakawa, Masatsugu Nakajima, Kazuma Fujimoto, Etsuo Hoshino, Yasushi Mitachi, Shiro Hamada, Tetsuya Mine, Yoshio Kawahara, Toshihiko Nagai, Nobuo Aoyama, Norimasa Yoshida, Keiichi Tadokoro, Nobuyuki Chiba, Yoshitaka Konda, Hiroshi Senoo, Tomohiko Shimatani, Masaki Inoue, Nobuhiro Sato M1478 Bioequivalence Between Esomeprazole 40 mg MUPS and Its Encapsulated Form Simona Talpes, Daniel Mascher, Reinhard Huber, Bernd Pfaffenberger P-174 ~ Denotes DDW Poster of Distinction

64 POSTER SESSIONS~CLINICAL SCIENCE AM-5:00 PM Hall F,~ Sponsored by: Gastrointestinal Oncology COLON CANCER: CLINICAL II Four-Dimensional Elastic Light-Scattering Fingerprinting M1479 (4D-ELF) Provides Accurate Risk Stratification for Human Colonic Neoplasia Stephen Y. Chang, Hemant K. Roy, Young Kim, Yang Liu, Michael J. Goldberg, Ramesh K. Wall, Vladimir Turzhitsky, Jonathan P. Horwitz, Vadim Backman Self-Assessed Priority of Common Preventive Health M1480 Services Relative to Colorectal Cancer (CRC) Screening Among Primary Care Residents: Results of the National Colorectal Cancer Roundtable (NCCRT) Survey Amy S. Oxentenko, Nisheeth K. God, Darrell S. Pardi, Robert A. Vierkant, Wesley O. Petersen, Joseph C. Kolars, Robert T. Flinchbaugh, Timothy O. Wilson, Katherine Sharpe, John H. Bond, Robert Smith, Bernard Levin, J. Bart Pope, Paul C. Schroy III, Paul J. Limburg Barriers/Motivators of Colorectal Cancer (CRC) M1481 Screening Among Primary Care Residents: Results of the National Colorectal Cancer Roundtable (NCCRT) Survey Amy S. Oxentenko, Nisheeth K. Goel, Darrell S. Pardi, Robert A. Vierkant, Wesley O. Petersen, Joseph C. Kolars, Robert T. Flinchbaugh, Timothy O. Wilson, Katherine Sharpe, John H. Bond, Robert Smith, Bernard Levin, J. Bart Pope, Paul C. Schroy III, Paul J. Limburg Clinical Significance of Incidental 18F-FDG M1482 Accumulation in the Gastrointestinal Tract Using PET- CT: Correlation with Endoscopic and Histopathological Sampling Miriam Thumshim, Ehab Kamel, Kaspar Truninger, Thomas Hany, Marc Schiesser, Michael Fried, Barbara Padberg, Gustav Von Schulthess, Katrin Stumpe Prospective Study of Flexible Sigmoidoscopy to Screen M1483 for Colorectal Cancer in HIV-Infected Patients 50 Years of Age and Older Edmund J. Bini, James Park, Fritz Francois Fluorescence-Tagging of Adenoma Surface Marl~er: M1484 Using Polyethylene Glycol (PEG) As a Linker Chi Zhang, Yah Feng, Timothy Mitchison What is the Appropriate Screening Protocol in HNPCC? M1485 Andrea E. de Jong, Fokko M. Nagengast, Fred H. Menko, Jan H. Kleibeuker, Gerrit Griffioen, Annemieke Cats, Hans F. A. Vasen Screening for Anal Cancer in HlV-Infected Men M1486 Jill Tinmouth St., Irving Salit, Marie Sano, William Chapman, Alice Lytwyn Prevalence and Characteristics of Adenomas in the M1487 Dutch General Population Andrea E. de Jong, Hans Morreau, Annemieke Cats, Gerrit Griffioen, Jan H. Kleibeuker, Lisbeth M H. Mathus-Vliegen, Fokko M. Nagengast, Hans F. A. Vasen Comparing Yield of FOBT and FS in a Screening M1488 Population Angelo Pera, Carlo Senore, Roberta DiPlacido, Arnaldo Ferrari, Roberto Ferraris, Marco Pennazio, Serafino Recchia, Alessandro Repici, Mario Rizzetto, Mauro Spandre, Delio Turco, Nereo Segnan M1489 M1490 M1491 M1492 M1493 M1494 M1495 M1496 M1497 M1498 M1499 M1500 M1501 M1502 M1503 Temporal Trends in New Diagnoses of Colorectal Cancer Presenting as Obstruction, Perforation or Emergency Admission: A Population-Based Study Linda Rabeneck, Lawrence Paszat, Deanna Rothwell, Jingsong He Cost-Effectiveness Analysis of Colorectal Cancer Screening by Immunochemical or Biochemical Faecal Occult Blood Tests Raquel Aguiar, Antonio Gimeno, Adolfo Parra-Blanco, David Nicolas, Daniel Deniz, Marta Garcia, Ana Hernandez, Fernando Leon, Pedro Serrano, Yoshinobu Eishi, Yasushi Sano, Enrique Quintero Factors Determining Colorectal Cancer Screening Discussions During Primary Care Visits Parita Patel, Samuel Forjuoh, Andrejs Avots-Avotins, Tushar Patel Colonoscopic Findings in 500 Average-Risk Patients Undergoing Colorectal Cancer Screening Charles Randall, Carlo M. Taboada, David Stump, Franz Zurita The Impact of Physicians' Personal Health Beliefs on Colorectal Cancer Screening Practices Kenneth Shieh, Dayna Early A Survey of Canadian Physicians' Choices for Their Own Colon Cancer Screening Mamoon Raza, Charles N. Bernstein, Harminder Singh, Alexandra Ilnyckyj Receipt of Colorectal Testing Prior to Colorectal Cancer Diagnosis: A Population-Based Study Gregory S. Cooper, Jonathan D. Payes Increased Fecal Calprotection Levels in Colorectal Cancer Are Caused by the Mucosal Production in the Neoplastic Tissue Nils Homann, Kim Luley, Diether Ludwig Is There an Effect of Gender on the Type of Initial Colorectal Evaluation? A Population Based Study Stacey Shapira, Deanna Rothwell, Lawrence Paszat, Jingsong He, Susan Stafford, Linda Rabeneck Colonoscopy and Stool-Based DNA Testing Preferrcd for Routine Colorectal Cancer Screening (CRCS) Subodh Lal, Philippe Zamor, Julic Glick, 1 imothy I lccrcn. Paul C. Schroy lii Proximal Migration of Colonic Polyps: An Analysis of 3,581 Polyps Found Among Chinese Over a Period of 9 Years James Y. W. Lau, Wai K. Leung, Janet F. T. Lee, Cat/Jail Cheung, Sara Fung, Joseph J. Y. Sung Gelatinolytic Activities of Matrix Metalloproteinase 2 and 9 in Gastric Cancer Moon Gi Chung, Yu Kyung Kim, Kx\ang An K\\on. Don,,, Kyun Park, Sun Suk Kim, Yeon Suk Kim. 5o ~ouno K~nn. Duck Joo Choi, Yu Jin Hwang. Ju Hyun Kim Low Awareness of Screening for Colorectal Cancer Among Adults Aged 50 to 74 Years S. Elizabeth McGregor, Robert J. Hflsden Survey of Primary Physicians Knowledge of Colorectal Cancer (CRC) Screening Shlomo Birkenfeld, Yaron Niv Findings on Screening Colonoscopy in a Community Hospital Kenneth I. O'Riordan, Scott Hammerman, Dean N. Silas Denotes DDW Poster of Distinction P-175

65 POSTER SESSIONSmCLINICAL SCIENCE M1504 M1505 Demographics and Clinical Predictors of an Advanced Lesion on Colonoscopy Thomas M. Zarchy, Linda S. Chan, Frank Tsai, John M. Lee, Rimma Shaposhikov Diagnosis of Small Bowel Tumors with Video Capsule Endoscopy - Report of 16 Cases Martin Keuchel, Christoph Thaler, Joerg Caselitz, Friedrich Hagenmueller M1516 M1517 A New Generation Probe for Laparoscopic Ultrasound Guided Biopsy: First Clinical Evaluation Peter Vilmann, Jacob Holm, Hassem Hassan Indication of Surgical Treatment for Intraductal Papillary Mucinous Tumor of the Pancreas (Ipmt) Judged by Long-Term, Periodical, Uhrasonograpic Follow-up Yamaguchi Taketo 1 M O N D A Y MAY 17 M1506 M1507 M1508 M1509 M1510 M1511 M1512 M1513 M1514 Analysis of Patient Demographics and Yield of Average- Risk Screening Colonoscopy One Year After Medicare Reimbursement Change Joseph Healy, Alan Chiemprabha, Jamal A. Ibdah Endoscopic Follow-up of 383 Patients with Colorectal Adenomas: An Observational Study in a Clinical Setting Daisy Jonkers, Justi Ernst, Ingrid Pladdet, Reinhold Stockbrugger, Wim Hameeteman Screening Colonoscopy for Colorectal Cancer Prevention, One Year Results from a Prospective Health Care Service Research in Bavaria (Germany) Berndt R. Birkner, S. Kleff, J. Thomas, R. Fritsche, A. Munte Efficacy of an Immunological Fecal Occult Blood Test for Colorectal Cancer Screening in a Southern European Population Adolfo Parra-Blanco, Antonio Gimeno, David Nicolas, Daniel Deniz, Begona Grosso, Maria Garcia, Ana Hernandez, Fernando Leon, Yoshinobu Eisbi, Yasushi Sano, Enrique Quintero Anatomic Location of Colorectal Cancer and Receipt of Previous Screening Gregory S. Cooper, Jonathan D. Payes Is the Pattern of Colorectal Cancer Changing? Avanthi Ragam, Mani Mahdavian The Clinical Utility of Digital Rectal Examination with Fecal Occult Blood Testing upon Hospital Admission Charles D. Scales Jr., Steve Fein, Gregory Samsa, Andrew Muir, Don Rockey Colorectal Cancer Screening (CRC) with Fecal Occult Blood Test (FOBT) and Total Colonoscopy. Immediate Results and Revision After Five Years Panades Agusti, Seoane Agustin, Torra Sandra, Nieto Miquel, Courtier Ricard, Andreu Montserrat, Bessa Xavier, Bori Felipe Prevalence of Colorectalcarcinoma in a High Risk Area of North Italy Angelo Franze', Vincenzo De Lisi, Carlo Missorini, Veronica Iori, Gabriella Di Cola, Beatrice Prati, Marta Maino, Federico Marcucci, Giorgio Nervi, Nadia Altavilla, Francesco Di Mario AM-5:00 PM Hall F ~ M1518 M1519 M1520 M1521 M1522 M1523 M1524 M1525 Usefulness of Color Doppler Ultrasonography in the Diagnosis of Anomalous Pancreaticobiliary Ductal Union Hiroki Kawashima, Yoshiki Hirooka, Akihiro Itoh, Senju Hashimoto, Terutomo Itoh, Kazuo Hara, Akira Kanamori, Naoki Ohmiya, Yasumasa Niwa, Hidemi Goto A Comparative Study of Barium Follow Through and Small Intestinal Ultrasound for the Investigation of Suspected Small Bowel Pathology in a District General Hospital Simon Cowlam, Nigel Grunshaw, Peter Trewby, James Anderson, Stephen Mitchell Identification of Organ Necrosis in Patients with Acute Pancreatitis by Echo-enhanced Sonography and Angio- CT Scan Steffen Rickes, Stefan Kahl, Sabine Klauck, Sven Kolfenbach, Peter Malfertheiner Videofluoroscopy and Image Analysis: A New Method for the Simultaneous Assessment of Gastric Emptying and Upper Gastrointestinal (GI) Motility in Humans Premysl Bercik, Elena F. Verdu, John Rawlinson, Stephen M. Collins, David Armstrong Oral Peppermint Oil Is a Useful Antispasmodic for Double-Contrast Barium Meal Examination Shigeaki Mizuno, Kimitoshi Kato, Yoshiki Ono, Hanzou Kurosaka, Kiyoshi Yano, Hiromo Abeta, Atsuhiko Takahashi, Yukimoto Ishii, Noriko Nakajima, Ariyoshi Iwasaki, Yasuyuki Arakawa Computer Aided Diagnosis (CAD) of Dysplasia in Barrett's Esophagus (BE) Using Endoscopic Optical Coherence Tomography (EOCT) Xin Qi, Michael V. Sivak Jr., David L. Wilson, Andrew M. Rollins Changes in Gene Expression in Human Gastric Epithelium Through Helicobacter pylori Eradication Ayako Yanai, Yoshihiro Hirata, Wataru Shibata, Yuzo Mitsuno, Motoyuki Otsuka, Tomoya Ohmae, Shin Maeda, Keiji Ogura, Haruhiko Yoshida, Takao Kawabe, Masao Omata Accuracy and Patient Preference in Evaluating Perianal Fistulas Using Hydrogen Peroxide-Enhanced Three- Dimensional Endoanal Uhrasonography and Endoanal Magnetic Resonance Imaging R. L. West, S. Dwarkasing, R. J. F. Felt-Bersma, W. R. Schouten, W. C. J. Hop, S. M. Hussain, Ernst Kuipers Sponsored by: Imaging and Advanced Technology ULTRASOUND AND OCT IMAGING M1515 Evaluation of a New Ultrasound Simulator in Ultrasound Education and Skill Assessment Christoph Terkamp, Martin Caselitz, Harald Reindell, Bita Boozari, Joerg Bleck, Michael P. Manns, Michael Gebel P Denotes DDW Poster of Distinction

66 POSTER SESSIONS~CLINICAL SCIENCE AM-5:00 PM Hall F ~ Sponsored by: Immunology, Microbiology & Inflammatory Bowel Disorders IBD GENETICS The Pattern of Evolution and Worldwide Distribution of M1526 CARD15 Variants as Evidence for Local Selection Pressure in the Historic European Populations Manuela Nemetb, Paul Grundmer, Claudia Willheim, Peter Ferenci, Christoph Gasche Polymorphisms in the MEP1A Gene: A Role in M1527 Inflammatory Bowel Disease (IBD)? Lee Min Yap, Daniel Lottaz, Tariq Ahmad, Lyna Zhang, David Van Heel, Dermot McGovern, Kenichi Negoro, Erwin Sterchi, Ian Sanderson, Ken Welsh, Derek Jewell The IBD-Genetics Consortium Provides Further M1528 Evidence for Linkage to the IBD4 Locus and Shows Interaction with Smoking Marieke Pierik, Huiying Yang, Michael M. Barmada, Juleen A. Cavanaugh, Robert M. Vlietinck, Kent Taylor, Paul Pavli, Steven Brant, Mark Silverberg, Judy Cho, Paulina Paavola, Jean-Pierre Hugot, Jochen Hampe, Vito Annese, Derek Jewell, Richard Duerr, Graham Radford-Smith, International IBD Genetics Consortium Localization of a Disease Susceptibility Locus in 6p in M1529 Japanese Patients with Ulcerative colitis g Eiki Nomura, Yoshitaka Kinouchi, Kenichi Negoro, Hiroko Abe, Masaki Tosa, Manabu Shiraki, Shinya Oomori, Mikako Sugimura, Mika Hiroki, Sho Takagi, Hiroyuki Aihara, Seiichi Takahashi, Nobuo Hiwatashi, Tooru Shimosegawa Crohn's Disease Is Associated with a Toll-Like Receptor M1530 (TLR)-9 Polymorphism Helga P. Torok, Laurian Tonenchi, Juergen Glas, Christian Folwaczny A TDT Study of Novel Polymorphisms in the Innate M1531 Immunity Genes Toll-Like Receptor (TLR) 2 and 4 in Inflammatory Bowel Disease (IBD) Marie Pierik, Greet Claessens, Nele Van Schuerbeek, Sofie Joossens, Paul Rutgeerts, Severine Vermeire Demand for Genetic Testing for Inflammatory Bowel M1532 Disease (IBD) Jennifer I. Appehon, Justine Mascarenhas, Mary J. Esplen, Kate Butler, David T. Rubin, Mark S. Silverberg The Influence of Smoking on Disease Susceptibility in M1533 Individuals at High Genetic Risk of Crohn's Disease Tariq Ahmad, Dermot McGovem, Sue Goldthorpe, David van Heel, Sara Marshall, Derek Jewell Association Between Polymorphism of Tumor Necrosis M1534 Factor Receptor 1A and Diminished Bone Density in Crohn's Disease J. J. Theal, Mark Silverberg, H. Steinhart, S. Irwin, G. R. Greenberg Pregnane-X-Receptor Polymorphism Is Associated with M1535 Steroid Resistance in Ulcerative Colitis Megan Dring, Carol Goulding, Nassir Mahmud, Richard Farrell, Rachel Cooney, Dermot Kellehor, Ross McManus M1536 M1537 M1538 M1539 M1540 M1541 M1542 M1543 M1544 M1545 Analysis of MICA Alleles in Japanese Patients with Ulcerative Colitis Mikako Sugimura, Yoshitaka Kinouchi, Kenichi Negoro, Seiichi Takahashi, Hiroyuki Aihara, Sho Takagi, Mika Hiroki, Shinya Oomori, Eiki Nomura, Manabu Shiraki, Masaki Tosa, Hiroko Abe, Nobuo Hiwatashi, Tooru Shimosegawa Multidrug Resistance Gene (MDR-1) Polymorphisms in a Refractory Crohns Disease Population Megan Dring, Jack Satsangi, lan Amott, Gwo-Tzer Ho, Dermot Kellehor, Ross McManus Influence of the Major Immunogenetic and Environmental Factors on the Crohn's Disease (CD) Behavior Alicia M. Sambuelli, Laura Murillo, Silvia Negreira, Anibal Gil, Sergio Huemos, Silvina Gon, Martin Toro, Paula Fernandez, Julio C. Bai, Amado S. Pena Regional Differences in the Prevalence of Single Nucleotide Polymorphisms in CARD15/NOD2 but Not in Toll-Like Receptor 4 (TLR4) Asp299Gly Polymorphism in Patients with Inflammatory Bowel Disease (IBD) Across Europe: Results from the EC-IBD Study Group Lene B. Riis, Frank Wolters, Camilla Solberg, Aria Vieira, Marieke Pierik, Mercedes Butron, Dolores Rodriguez- Martinez, Greet Claessens, Joao Freitas, Morten Vam, Reinhold Stockbmgger, Ebbe Langholz Granulomas, Pattern Recognition Receptors (PRR) and Phenotypes of Crohn's Disease (CD) Marie Pierik, Gert De Hertogh, Severine Vermeire, Sofie Joossens, Peter Van Eyken, Greet Claessens, Gert Van Assche, Karel Geboes, Paul Rutgeerts Weak Evidence for Linkage Replication to the IBD2 Locus from a Large International Collaborative Dataset Betty Q. Doan, Joan E. Bailey-Wilson, Michael M. Barmada, Juleen A. Cavanaugh, Huiying Yang, Jochen Hampe, Vito Annese, Derek P. Jewel, Richard Duerr, Graham Radford- Smith, Kirsten E. Adams, Severine Vermeire, Kent Taylor, Mark S. Silverberg, Judy H. Cho, Jean-Pierre Hugot, Steven R. Brant, Paulina Paavola, International IBD Genetics Consortium NOD2 Polymorphisms and Their Relalionship to Serologic Markers of Disease in Children with IBD James Markowitz, Jeffrey Hyam~, Jonathan I!\'anq, Da\id Mack, Maria Oliva-Hemker, Anthony Otley, Marialq Pfefferkorn, Joel Rosh, Vasmldhara I'olia, William I recltq. Katie M. Smith The Vitamin D-Receptor Promoter CDX2-SiIe Polymorphism in Inflammatory Bowel Disease, Dysplasia and Neoplasia Konstantia-Maria Chavele, P Erwin, gvlargarct Hoper. R Smyth, R. J. Maxwell, Frederick C. CalnpbeH. Julian R I Wahers Linkage of Inflammatory Bowel Disease to IBD3 and Association to TNFo~-576c with Possible Interaction with NOD2/CARD15 Carolien Panhuysen, Juleen Cavanaugh, Huiying Yang, Michael M. Barmada, Severine M. Vermeire, Jerry Rotter, Paulina Paavola, Jochen Hampe, Vito Annese, Derek Jewell, Richard Duerr, Graham Radford-Smith, Nathan O'Callaghan, Steven Brant, Mark Silverberg, Judy Cho, Jean-Pierre Hugot, International IBD Genetics Consortium Association of Inflammatory Bowel Diseases with Familial Mediterranean Fever Gene MEFV Lyna Zhang, Qian Cao, Tariq Ahmad, Dermot McGovern, Lee Min Ming Yap, Derek Jewell Denotes DDW Poster of Distinction P-177

67 POSTER SESSIONS--CLINICAL SCIENCE M O N D A Y MAY 17 M1546 M1547 M1548 M1549 M1550 M1551 M1552 M1553 M1554 M1555 M1556 M1557 Comparisons of Gene Expression in Non-Inflamed Colonic Mucosa Reveal Over-Representation of Genes from IBD Susceptibility Regions in IBD Patients Compared with Control Subjects Jorgen Olsen, Jakob B. Seidelin, Lene T. Kirkeby, Jesper T. Troelsen, Ole H. Nielsen Fine Mapping of the 5q31 Risk Haplotype in Crohn's Disease Clive Onnie, Sheila Fisher, Muddassar Mirza, Jochen Hampe, Alastair Forbes, John Mansfield, Jeremy Sanderson, Stefan Schreiber, Cathryn Lewis, Christopher Mathew Novel Genes Are Implicated by mrna Differential Display in Individuals with Ulcerative Colitis Mark Varsanyi, Sofie Lundberg, Per M. Hellstrom Phenotypic Concordance in Monozygotic Twin Pairs with Ulcerative Colitis Jonas Halfvarson, Tine Jess, Lennart Bodin, Curt Tysk, Vibeke Binder, Gunnar Jarnerot NOD2/CARD15 and TNF Promoter Polymorphisms in a UK IBD Population Sarah Waller, Mark Tremelling, Francesca Bredin, Jeremy Woodward, Stephen Middleton, Miles Parkes Analysis of Interleukin-12 Gene Polyrnorphisms in the Susceptibility to Crohn's Disease Toon Zwiers, Diana Seegers, Roel Heijmans, Michelle Borm, Andreas Koch, Jochen Hampe, Stefan Schreiber, Salvador Pena, Gerd Bouma The Analysis of Mutagenic Mechanisms in Patients with Ulcerative Colitis Truc Nguyen, Richard Colletti, Terri Messier, Patrick O'Neill, Barry Finette The Presence of CARD15 Polymorphisms Is Linked with Higher ASCA Titers in Crohn's Disease Harald Peeters, Bert Vander Cruyssen, Debby Laukens, Paul Coucke, llse Hoffman, Filip De Keyser, Martine De Vos Impact of PPAR~/ Gene Variants on Crohn's Disease Phenotypes: Association of the Functional Pro12Ala Polymorphism with Penetrating Behaviour Alexandra-Chloe Villani, Line Dufresne, Peter Suenaert, Alain Bitton, Alan B. R. Thomson, Gary E. Wild Genetic Susceptibility to Ulcerative Colitis (UC) in the Chinese Han Population: Association with TNF Polyrnorphisms Qian Cao, Tariq Ahamd, Min Gao, Wei L. Hu, Derek Jewell, Jian M. Si The 1007fs insc mutation in NOD21CARD15 in Crohn's Disease Patients from Hungary: Association with Stenotic Disease Behaviour and Ileal Resections Carsten Buning, Tamas Molnar, Ferenc Nagy, Janos Lonovics, Bettina Bochow, Renita Weltrich, Janine Genschel, Hartmut Schmidt, Herbert Lochs Consistency of the Association Between NOD2/CARD15 Polymorphisms and Crohn's Disease Susceptibility and Phenotype Across Diverse Populations: A Meta-Analysis Michael Economou, Thomas A. Trikafinos, Konstantinos Loizou, Epameinondas Tsianos, John P. A. Ioannidis M1559 M1560 M1561 M1562 M1563 M1564 M1565 M1566 M1567 M1568 M1569 IL-18 Promoter Polymorphism as a New Genetic Susceptibility Factor for Inflammatory Bowel Diseases Stephan Haas, Andreas Koch, Stefan Schreiber, Iris Reinhard, Manfred V. Singer, Ulrich Boecker Concordance of Serologic and Genetic Markers in Twins with Inflammatory Bowel Disease Sofie Joossens, Marielle Romberg-Camps, Severine Vermeire, K. De Boer, Greet Claessens, Maurice Russel, Marie Pierik, Nele Van Schuerbeeck, Robert Vlietinck, Xavier Bossuyt, Paul Rutgeerts Systematic Functional Analysis of NOD2 Reveals Regulatory Mechanisms and Critical Residues Involved in Muramyl Dipeptide Recognition Mathias Chamaillard, Tsuyoshi Tanabe, Yasunori Ogura, Li Zhu, Su Qiu, Junya Masumoto, Partho Ghosh, Anthony Moran, Martina M. Predergast, Gerard Tromp, Charlene J. Williams, Naohiro Inohara, Gabriel Nunez Evaluation of SNPs in TNF (C-857T) and MDR1 (C3435T) As Susceptibility Factors for IBD Peter Croucher, Jochen Hampe, Silvia Mascheretti, Christopher G Mathew, Ulrich R. Foelsch, Stefan Schreiber TNF-Alpha and IL-10 Snps Act Together to Predict Disease Behaviour in Crohn's Disease Beth Fowler, Georgia Hume, Graham Radford-Smith TLR4 Asp299Gly, Inflammation and Response to Infliximab in CD Marie Pierik, Tibor Hlavaty, Greet Claessens, Nele Van Schuerbeek, Sofie Joossens, Paul Rutgeerts, Severine Vermeire A Polymorphism in Insulin-Lik~ ~kl~wth Factor 1 Gene May be Associated ~a ~/~]~swl~zing Behaviour in Colonic.~#iJa~s~b~l~ ~i~ ~l w-- N~ lo~s~e~ ~elaiche, Cecille Libioulle, Julie Tl~sIA~n~ Vijverman, Rosita Winkler, Fabienne ElYafi, Michel Malaise, Michel Georges, Edouard Louis Increased Frequency of a Single Nucleotide Polymorphism in Hypothetical Gene FLJ21425 in Patients with Crohn's Disease in a Louisiana Population Elizabeth Mannick, San-San Ng, Rebecca Brennan, Mariela Gastanaduy, John Udall Jr., Raynorda Brown, Eberhard Schmidt-Sommerfeld, Bronya Keats, Adriana Zapata- Velandia Genetic Crohn's Disease. A Different Entity Than Sporadic. A Study in Monozygotic Twins Jonas Halfvarson, Francesca Bresso, Curt Tysk, Sven Pettersson, Gunnar Jamerot polymorphisms of the Autoimmune-Regulator (AIRE) Gene in Correlation with Presence of Autoantibodies in Inflammatory Bowel Disease Laurian Tonenchi, Helga P. Torok, Juergen Glas, Uwe Schiemann, Christian Folwaczny NOD2/CARD15 and TLR4 Gene Polymorphisms and Histopathological Features of Surgical Specimens in Crohn's Disease Gert De Hertogh, Marie Pierik, Severine Vermeire, Sofie Joossens, Greet Claessens, Peter Van Eyken, Gert Van Assche, Paul Rutgeerts, Karel Geboes M1558 High Frequency of SNP8, 13 and Further exon4 NOD2/ CARDI5 Mutations in 527 Hungarian Patients with Crohn's Disease Peter L. Lakatos, Laszlo Lakatos, Ferenc Szalay, Claudia Willheim-Polli, Zsoh Tulassay, Tamas Molnar, Werner Reinisch, Janos Papp, Hungarian IBD Study Group, Peter Ferenci M1570 Prevalence and Significance of Mutations in the Familial Mediterranean Fever Gene in Patients with Crohn's Disease Matt Waterman, Amir S. Karban, Efrat Dagan, Rami Eliakim, Amnon Herman, Shula Nesher, Batia Weiss, Drora Berkowitz, Raanan Shamir, Ruth Gershoni-Baruch P Denotes DDW Poster of Distinction

68 POSTER SESSIONS--CLINICAL SCIENCE M1571 Polymorphisms of the Lipopolysaccharide-Signaling Complex in Inflammatory Bowel Disease Helga P. Torok, Juergen Glas, Laurian Tonenchi, Christian Folwaczny AM-5:00 PM Hall F ~_~ Sponsored by: Motility & Nerve-Gut Interaction ANORECTAL MOTILITY AND DISORDERS Evidence for the Presence of Angiotensin 1I (Ang II) M1572 Biosynthetic Machinery in the Internal Anal Sphincter (IAS): Role in the Basal Tone Marcio De Godoy, Stephen Dunn, Satish Rattan Sacral Nerve Stimulation for Faecal Incontinence M1573 Secondary to Obstetric Damage: Superior to Sphincter Repair Michael E. D. Jarrett, Carolynne Vaizey, Richard Cohen, John John Nicholls, Michael A. Kamm Influence of Capsaicin on Rectal Sensorimotor Function M1574 in Man Maura Corsetti, Rita Vos, Jozef Janssens, Jan Tack Pseudoaffective Response to.~alloon Distention M1575 in Healthy Male.'~pla~nle~ ~'~ Rober_t~,!~~l~, ~lf~ed Bayati, Yi Mao, ~ ~ I ~, ~revor Murphy, Subhas Ganguli, Adrian R. ~d?'lr-pton, Gervais Tougas Application of L-Erythro Methoxamine Gel Increases M1576 Anal Resting Pressure in Healthy Volunteers Pasha Nisar, Hans-Juergen Gruss, Jeffrey Thompson, Norman Barras, Debbie Bush, Austin Acheson, John Scholefield The Application of Sacral Nerve Stimulation to the M1577 Disrupted Anal Sphincter Angela Gardiner, Stephen Pillinger, Tariq Ahmed, Graeme S. Duthie Anal Sphincter Function and Rectal Capacity Affect M1578 Anorectal Sensation and Continence in Health Mark Fox, Wemer Schwizer, Dieter Menne, Michael Fried, Miriam Thumshirn Abnormal Neo-rectal Contractility or "Irritable Neo- M1579 rectum" After Preoperative Radiotherapy and Rectal Resection for Rectal Carcinoma Roel Bakx, Frederik Slors, Willem Bemelman, Jan Van Lanschot, Guy Boeckxstaens Anorectal Motor and Sensory Function After 3D M1580 Conformal Radiation Therapy for Carcinoma of the Prostate is Similar to the 2D Approach Addolorata Di Matteo, Rochelle Botten, Richard Holloway, Robert Fraser, Eric Yeoh Compression of Peri-Rectal Structures During Rectal M1581 Distension Guido Basilisco, Annalisa Dal Lago, Maura Corsetti, Pietro Biondetti, Alberto Minetti Rectal Contractions are Part of Normal Defecation M1582 Albena Halpert, Lenore Keck, Douglas A. Drossman, William E. Whitehead Anorectal Physiology Predicts Response to Conservative M1583 Medical Management of Fecal Incontinence Steve Heymen, Yolanda Scarlett, William E. Whitehead M1584 M1585 M1586 M1587 M1588 M1589 M1590 M159I M1592 M1593 M1594 M1595 M1596 M1597 M1598 Simple VAS Versus St. Mark's Grading for the Assessment of Fecal Incontinence Satish S. C. Rao, Vanitha Singaram, Ramazan Ozturk, Mary Stessman, Bridget Zimmerman Gender Effects on the Innervation Pattern of the External Anal Sphincter of Healthy Subjects Paul Enck, Heidemarie Hinninghofen, Ming Liu, Heiko Franz, Fernando Azpiroz, Roberto Merletti Reproducibility of Rectal Sensation and Compliance in Healthy Subjects Filippo Cremonini, Michael Camilleri, Irene Ferber, E. Janet Castillo, Alan Zinsmeister Long - Term Results of Chemical Sphincterotomy for Chronic Anal Fissure (CAF): A Prospective Study Joseph Lysy, Israeli Eran, Sharon Levy, Gloria Rozentzweig, Nourit Strauss-Liviatan, Goldin Eran Comparison of Sensory Perception and Reproducibility of Electrical and Mechanical Stimulation of the Healthy Human Rectum Mary Louise Harris, Anthony Hobson, Shaheen Hamdy, David Thompson, Louis Akkermans, Qasim Aziz Abnormalities in the Intermuscular plexus and Interstitial Cells of Cajal may Contribute to the Pathology of Rectal Prolapse Catherine Streutker, Cathy Ross, Robert H. Riddell The Effects of the First Dose and 2-Weeks of Daily Administration of Sildenafil on Anal Sphincter Characteristics and Rectal Sensation in Healthy Men Mark Milone, John DiBaise Anal Sphincter and Vaginal Delivery: A 5-Year Followup of 197 Primiparous Women Henri Damon, Luc Henry, Georges Mellier, Francois Mion Does Ulcerative Colitis Lead to Persistent Changes in Rectal Perceptions? Dulce-Maria Cruz-Santamaria, Enrique Rey, Julio Garcia- Paredes, Juan-Luis Mendoza, Carlos Taxonera, Cristina Alba, Manuel Diaz-Rubio Inhibitory Effect of Rectal Distention on Gastric Tone Is Not Mediated via Cholinergic Pathway in Dogs Yong/.el, Hongbing Zhu, Jiande Z. Chen Volmne Measurements of the Anal Sphincter Complex Using 3D Endoanal Uhrasonography R. k. West, R. J. F. Felt Bersma, B E. Plansctn, t!rn>t Kuipers Comparing Anal Sphincter Volumes in Continent and Incontinent Parous Females Using 3D-Endoanal Uhrasonography R. L. West, R. J. F. Felt-Bersma, B. E. Hansen, \V. R. Schouten, Ernst Kuipers A New Questionnaire for Fecal Incontinence and Constipation (FICA) Barbara Seide, G Richard Locke 111, Cathy ',chic,k. Akin Zinsmeister, Adil E. Bharucha Altered Rectal Sensorimotor Function in Patients with the Irritable Bowel Syndrome (IBS) Magnus Simren, Gisela Ringstrom, Pia Agerforz, Anette Lindh, Iris Posserud, Einar Bjornsson, Hasse Abrahamsson Comparison of Air Coupled Balloon Anorectal Manometry Catheters with Water Perfused Anorectal Manometry Catheters John Fang, Kristen Hilden, Kathryn Peterson, Ashok Tuteja Denotes DDW Poster of Distinction P-179

69 POSTER SESSIONSnCLINICAL SCIENCE M1599 M1600 Rectal Compliance Is Disturbed in Children with Severe Constipation Wieger P. Voskuijl, Marc A. Benninga, Rijk van Ginkel, Guus A. Hart, Jan A. Taminiau, Guy E. Boeckxstaens Is There any Interest in Anal Function of Subjects with Solitary Ulcer Syndrome? Olivia Morio, Laurent Siproudhis, Ludivine Falize, Veronique Desfoumeaux, Alain Ropert, Jean-Francois Bretagne M M1612 Peri-menstrual Bloating in Patients with Irritable Bowel Syndrome (IBS) Is Not Associated with Abdominal Distension and May Be Related to Visceral Hypersensitivity Richard Lea, Brian Reilly, Peter J. Whorwell, Lesley A. Houghton Psychosocial Correlates of Symptoms in Functional Dyspepsia (FD) Michael P. Jones, Eric Lee, Michael D. Crowell M O N D A Y MAY 17 M1601 M1602 M1603 M1604 Puborectalis and External Anal Sphincter in Anal Canal Pressure: Effect of Pudendal Nerve Blockade Jianmin Liu, Noelani Guaderrama, Charles W. Nager, Dolores H. Pretorius, Geoff Sheean, Ghada Kalsho, Ravinder K. Mittal Colorectal Motor and Sensory Function in Constipated and Non-Constipated Patients After Hysterectomy Patrick van der Veek, Frederik Timmermans, Philomeen Weijenborg, Ad Masclee External Anal Sphincter Contraction During Balloon Distention: Does This Represent an Anismus Pattern? Saeid Goshtasbi, Moises A. Garcia, Walter J. Hogan, Reza Shaker Influence of Citalopram Administration on Rectal Adaptive Relaxation in Diarrhea-Predominant IBS Patients and Healthy Controls Tessa Kilkens, Robert-Jan Brummer, Adriaan Honig, Michiel van Nieuwenhoven AM-5:00 PM Hall F :r4~_~ Sponsored by: Motility & Nerve-Gut Interaction FUNCTIONAL GI DISORDERS: SYMPTOMS, DIAGNOSIS AND EPIDEMIOLOGY M1605 M M M M1609 M Post-Infectious Irritable Bowel Syndrome in Patients with Shigella Infection: A Prospective Case-Control Study Sang Won Ji, Hyojin Park, Dock Yong Lee, Sang-In Lee The Spectrum of Functional Dyspepsia with Delayed Gastric Emptying and Idiopathic Gastroparesis Jan Tack, Philip Caenepeel, Joris Arts, Raf Bisschops, Kristen Verbeke, Jozef Janssens Relationship Between Upper Gastrointestinal Symptoms and Partial Gastric Volumes Measured by 3-Dimensional Uhrasonography Niels van Lelyveld, Bob Scheffer, Marco Mundt, Melvin Samsom Biliary Colic Is Highly Prevalent, but Is Not the Main Indication for Cholecystectomy, in IBS Subjects with Gallstones. MICOL Population-based Study Enrico Corazziari, Adolfo Attili, Claudio Angeletti, Adriano De Santis Alteration in Heart Rate Variability During Colonic Distension in Irritable Bowel Syndrome Clinton Ng, Ross Hansen, Allison Malcolm, John Kellow Is Rectal Hypersensitivity in Irritable Bowel Syndrome (IBS) Only Present in Tertiary Care Patients? Magnus Simren, Gisela Ringstrom, Anette Lindh, Pia Agerforz, Einar Bjomsson, Hasse Abrahamsson M1613 M1614 M1615 M1616 M1617 M1618 M1619 M1620 M1621 M1622 M1623 Small Bowel Manometry Findings Cannot Predict Small Intestinal Bacterial Overgrowth (SIBO) in Patients with Irritable Bowel Syndrome (IBS) Iris Posserud, Gisela Ringstrom, Pia Agerforz, Anette Lindh, Per-Ove Stotzer, Einar S. Bjomsson, Hasse Abrahamsson, Magnus Simren The Placebo Effect in Irritable Bowel Syndrome (IBS) Trials: A Meta-analysis Sonal M. Patel, Sun Myeong Ock, William Stason, Anna Legedza, Lisa Conboy, Catherine E. Kerr, Eric Jacobson, Katia Canenguez, Eoin Kelly, Ted Kaptchuk, Anthony J. Lembo Irritable Bowel Syndrome and Fibromyalgia: Sharing a Common Endogenous Pain Inhibitory System Deficiency Patricia Bourgault, Itachi Falanga, Judith Parenteau, Nancy Julien, Ghislain Devroede, Alain Watier, Serge Marchand Identification of Irritable Bowel (IBS) Patients with Alternating Bowel Habits William E. Whitehead, Olafur S. Palsson, Rona L. Levy, Andrew D. Feld, Michael Von Korff, Marsha J. Turner, Douglas A. Drossman, Michael D. Crowell Beta-Adrenergic Receptor Activity in Irritable Bowel Syndrome: A Candidate for Biologic Marker Hyunseo Kim, Poong-kyul Rhee, Jun Haneg Lee, Young-Ho Kim, Jae J. Kim, Jong Chul Rhee, Eun Ho Kang, Bum-Hee Yu Natural History of the Functional GI Disorders: A Population-Based Study Nicholas J. Talley, Giles R. Locke Ill, Cathy D. Schleck, Hiedi M. Treitline, Patrick H. Griffin, Alan R. Zinsmeister Smoking, Irritable Bowel and Esophageal Acid Exposure: An Insight into the Nature of Symptoms of Gastroesophageal Reflux Joseph Zimmerman Association Between Dieting Practices and GI Symptoms and IBS Among Participants in a Weight Loss Program Rona L. Lew, Robert W. Jeffery, Jennifer Linde, Catherine R. White, Michelle D. Garner, Kayla A. Feld, William E. Whitehead Post-Cholecystectomy Diarrhea: A Prospective Study of Incidence Suzanne Skoog, Julie Simonson, Amindra Arora, Nancy Diehl, W. Scott Harmsen, G. Richard Locke III, George Longstreth, Yvonne Romero, Johnson Thistle, Alan Zinsmeister, Adil E. Bharucha Which Rapid Distension Paradigm Discriminates Best Between IBS Patients with Diarrhea, Constipation and Healthy Controls? Clive H. Wilder-Smith Can Symptoms Predict the Presence of Visceral Hypersensitivity in Patients with Irritable Bowel Syndrome? Sjoerd D. Kuiken, Robert Lindeboom, Guido Tytgat, Guy E. Boeckxstaens P-180 ~ Denotes DDW Poster of Distinction

70 v POSTER SESSIONS--CLINICAL SCIENCE M1624 M1625 M1626 M1627 M1628 M1629 M1630 M1631 M1632 M1633 M1634 M1635 M1636 M1637 Confidence in the Diagnosis of Functional Gastrointestinal Disorders: Variability Among Trainees, Internists and Gastroenterologists Nirmala Gonsalves, Qing Zhang, Colin Howden, Ikuo Hirano Impact of Functional Gastrointestinal Disorders (FGIDs) on Presentation and Outcome of Patients Undergoing Laparoscopic Anti-Reflux Surgery (LARS) Juan M. Perrone, Ray E. Clouse, Chandra Prakash, Margaret M. Frisella, Kenneth E. Freedland, Nathaniel J. Soper Visceral Sensitivity in Patients with Coeliac Disease (CD) and Irritable Bowel Syndrome (IBS) Maria Pia Caldarella, Flora Sacco, Francesco Laterza, Angelo Milano, Balatsinou Crisanthy, Matteo Neri Overlap of IBS and Dyspepsia: How Much Is Explained by Upper Abdominal Pain Associated with Bowel Habit? E. Janet Castillo, G. Richard Locke II1, Michael Camilleri, Gianrico Farrugia, Larry S. Brown, Alan Zinsmeister, Nicholas J. Talley Irritable Bowel Syndrome After Salmonella Gastroenteritis: One Year Follow-up Prospective Cohorts Study Fermin Mearin, Manel Perez-Oliveras, Antonia Perello, Jordi Vinyet, Albert Ibanez, Monica Perona, Jordi Coderch Tryptophan Depletion Study in Irritable Bowel Syndrome (IBS) Jonathan Shufflebotham, Scan Hood, John Potokar, Christopher Probert The Parental Worries of Recurrent Abdominal Pain Questionnaire: Do Parental Cognitions Distinguish Consulters from Non-Consuhers? Miranda A. L. van Tilburg, Neeta Venepalli, Olafur S. Palsson, William E. Whitehead Recurrent Abdominal Pain (RAP): The Relationship Between Illness Behavior (IB) and Health Services Consulting Neeta Venepalli, Miranda A. L. van Tilburg, William E. Whitehead Pelvic Floor Dysfunction in Irritable Bowel Syndrome with Constipation Gillian Prott, Ross D. Hansen, John E. Kellow, Allison Malcolm Prevalence and Characteristics of Irritable Bowel Syndrome Among Women with Chronic Pelvic Pain Rachel E. Williams, Katherine E. Hartmann, Robert S. Sandier, William C. Miller, John F. Steege The Effect of Bowel Habit and Time of Day on the Relationship between Abdominal Bloating and Visible Distension in Patients with Irritable Bowel Syndrome (1BS) Richard Lea, Brian Reilly, Peter J. Whorwell, Lesley A. Houghton Evidence of High Breath H2 Gas Excretion in IBS Patients Submitted to Lactose Tolerance Test Carlos Felipe Bernardes-Silva, Antonio Atilio Laudanna Overlapping Functional Gastrointestinal Disorders in Patients with Gastroesophageal Reflux Disease (GERD) Justin C. Y. Wu, Carrian M. Y. Cheung, Jessica Y. L. Ching, Wayne K. W. Chan, Francis K. L. Chan, Joseph J. Y. Sung Testing a Definition of Predominantly Alternating Bowel Habits in IBS Using the Previously Validated Rome Composite Score (RCS) Questionnaire Mark Pimentel, Sandy Park, Yuthana Kong M1638 M1639 M1640 M1641 M1642 M1643 M1644 M1645 M1646 M1647 M1648 M1649 M1650 M1651 M1652 Is Irritable Bowel Syndrome a Confounding Factor in Community Studies of Gastro-Oesophageal Reflux Disease? Imtiyaz Mohammed, Peter Nightingale, Nigel Trudgill Hypercoagnlability Is Overwhelmingly Present (93%) in Patients with Severe Gastroparesis Kevin Blanchard, William Rock, Robert Schmieg, Farshid Araghizadeh, Karen Borman, Anil Minocha, Thomas L. Abell The Risk of Abdominopelvic Surgery Is Increased Among Patients with Irritable Bowel Syndrome (IBS) J. Alexander Cole, Jodie M. Sherman, David L. Earnest, Jason M. Yeaw, Jennifer A. Cutone, Braden Kuo, Alexander M. Walker Dysmotility-like Upper G1 Symptoms (dmugi) : Prevalence, Impact and Sociodemographic Factors in the Canadian Population: Findings from the DIGEST Study Ying Chen, Andrew Eggleston, Gervais Tougas Gender Differences in Functional Bowel Disorders Johann Hammer, Nicholas J. Talley The ROME II Criteria for Functional Pediatric Disorders of Defecation: Are They Adequate for Children with Fecal Soiling? Vera Loening-Baucke Influence of Intragastric Balloon in the Assessment of Gastric Accommodation Hui Ouyang, Jieyun Yin, Jiande Chen Prevalence of Constipation and Irritable Bowel Syndrome in Patients After Hysterectomy Patrick van der Veek, Frederik Timmermans, Philomeen Weijenborg, Ad Masclee Comparison of Functional Dyspepsia Patients with or Without Meal-Related Symptoms Jan Tack, Raf Bisschops, Philip Caenepeel, Jozef Janssens Relationship of Sleep and Autonomic Characteristics to Symptom Severity in Women with Irritable Bowel Syndrome Monica Jarrett, Robert L. Burr, Kevin C. Cain, Margaret M. Heitkemper Mucosal Expression of IFN-'y and IL-4 in Irritable Bowel Syndrome Masahiro Ohtani, Takeshi A:uma. Yukinao Yamacaki. Yosbiyuki Ito, Atsushi Muramatsu. "1 omo} uki Okuda, Masaru Kuriyama Are Functional GI Disorders Often Associated with GERD? Results of a French Smwey Inw)lving Adult Patients Presenting with GERD Lionel Bueno, Francoi> Guillemot, Philippe Ducroltc Constipation in Children: Incidence in a Population Based Birth Cohort Denesh K. Chitkara, Heiko De Schcpper, Mat} ] Ru~l<~'v Amy L. Weaver, Slavica K. Katusic, Giles R Locke HI Nicholas J. Talley Validation of a Brief Inventory for Diagnosis and Monitoring of Symptomatic Gastroesophageal Reflux Joseph Zimmerman Is There a Relationship Between Disturbed Gastric Motor and Sensory Function and Health-related Quality of Life in Functional Dyspepsia? Sebastian Haag, Sefik Tagay, Matthias Langkafel, Nicholas J. Talley, Wolfgang Senf, Gerald Holtmann Denotes DDW Poster of Distinction P-181

71 POSTER SESSIONSDCLINICAL SCIENCE M O N D A Y MAY 17 M1653 M1654 M1655 M1656 M1657 M1658 M1659 M1660 M166I M1662 M1663 M1664 M1665 The Comparative Epidemiology of IBS Among Settled and Nomadic Bedouins in Southern Israel Ami D. Sperber, Pesah Shvartzman, Michael Friger, Alex Fich The Impact of Health-related Quality of Life in Functional Dyspepsia: Consulters vs. Non-consulters. A Combined Population and Referral Based Study Evelyn Maldonado-Lopez, Sebastian Haag, Elisabeth Grote, Wolfgang Senf, Gerald Holtmann Water Load Test in Children with Abdominal Pain, Obesity, and Good Health Teri H. Lavenbarg, Caroline E. Danda, Jose T. Cocjin, Jon T. Gertken, Ananthamani Sreenivas, Craig A. Friesen, Linda Andre, Eleanor Welchert, Jennifer V. Schurman, Paul E. Hyman Symptom Turnover Among Community Subjects with Irritable Bowel Syndrome (IBS) and/or Functional Dyspepsia (FD) Natasha A. Koloski, Philip M. Boyce, Nicholas J. Talley Prevalence and Impact of Fecal Incontinence in Women Adil E. Bharucha, G. Richard Locke, Kimberly McKeon, Barb Seide, Cathy Schleck, Alan R. Zinsmeister, L. Joseph Melton II1 Inter-rater Reliability of the Rome Criteria in Children Miguel Saps, Carlo Di Lorenzo Relationship Between Antral Distension and After Meal Symptoms in Functional Dyspepsia (FD) Nadia Pallotta, Patrizio Pezzotti, Enrico Corazziari The Role of Hypersensitivity to Colonic Gas in the Pathophysiology of Symptoms in Functional Patients Michele Di Stefano, Emanuela Miceli, Antonio Missanelli, Samanta Mazzocchi, Gino Roberto Corazza Tegaserod Improves Abdominal Bloating Without Modifying Intestinal Gas Production Capacity Michele Di Stefano, Antonio Missanelli, Emanuela Miceli, Samanta Mazzocchi, Gino Roberto Corazza The Prevalence and Social Impact of Functional Dyspepsia in Taiwan: A Questionnaire Survey Based on Rome I and II Criteria Ching-Liang Lu, Hui-Chu Lang, Full-Young Chang, Sun- Sang Wang, Chih-Yen Chen, Jiing-Chyuan Luo, Shou-Dong Lee Predictive Factors of Irritable Bowel Syndrome (IBS) Evolution: One-Year Prospective Evaluation in 517 Cases (RITMO STUDY) Fermin Mearin, Xavier Badia, Agustin Balboa, Jaurne Benavent, Antonio Maria Caballero, Enrique Dominguez, Vicente Garrigues, Josep Maria Pique, Montse Roset Depression Influences Symptom Presentation in Pediatric Patients with Recurrent Abdominal Pain Cheryl A. Little, S. E. Williams, L. S. Walker Cardiologists ManageMmany of the Newly Diagnosed Noncardiac Chest Pain (NCCP) Patients and Prefer to Refer the Others to a Primary Care Physician (PCP) Ronnie Fass, Joy N. Beeler, Sara Habib, Sara Risner Sensory Defects in Clinical Subgroups of IBS Patients M1668 Clive H. Wilder-Smith AM-5:00 PM Sponsored by: Pancreatic Disorders Hall F CHRONIC PANCREATITIS/PANCREATIC CANCER/ EXPERIMENTAL PANCREATITIS I Distinct Pattern of Free Fatty Acids in Chronic M1669 Pancreatitis Ina Mautsch, Konstantin Mayer, Wemer Seeger, Herbert Lochs, Johann Ockenga A New Clinicopathological Entity of IgG4-related M1670 Autoimmune Disease Terumi Kamisawa, Nobuaki Funata, Yukiko Hayashi, Hitoshi Nakajima, Atsutake Okamoto Nitric Oxide and Tumor Necrosis Factor Alpha in M1671 Chronic Alcoholic Pancreatitis Maria C. Siqueira Sr., Paula Rocha, Teresa Antunes, Miguel Cameiro de Moura Prevfilence of Pancreatic Duct (PD) Abnormalities in M1672 Patients Undergoing Liver Transplant for Primary Sclerosing Cholangitis (PSC) Tyler Stevens, Darwin L. Conwdi, Gregory Zuccaro, John Vargo Mortality and Survival in Chronic Pancreatitis: Has It M1673 Changed Over the Last 20 Years? Jianlin Xie, Nakechand Pooran, Cindy Huang, Robert Brunner, Angelo Fernandes, Simmy Bank Endoscopic Therapy of Chronic Pancreatitis in M1674 Children Marianna Arvanitakis, Myriam Delhaye, Marie Daguzan, Celso Matos, Michel Cremer, Jacques Deviere Pancreatic Fistula (PF) in the Course of Chronic M1675 Pancreatitis : Non-Invasive Diagnostic Methods and Therapeutic Strategies Dermot O'Toole, Marie-Pierre Vullierme, Philippe Ponsot, Valerie Calmels, Frederique Maire, Olivia Hentic, Pascal Hammel, Philippe Lew, Reza Kianmanesh, Alain Sauvanet, Jacques Belghiti, Vilgarin Valerie, Philippe Ruszniewski The Evaluation of Pancreatic Juice Cytology for M1676 Pancreatic Cancer by Endoscopic Nasal Pancreatic Drainage Takanobu Yoshimoto, Shujiro Yazumi, Hiroshi Hisatsune, Kazunori Hasegawa, Masanori Asada, Sakae Mikami, Akiyoshi Nishio, Tsutomu Chiba Exaggerated Cytokine Response of Peripheral Blood M1677 Mononuclear Cells (PBMCs) to Endotoxin in Pancreatic Cancer Raghuram P. Reddy, Suresh T. Chari, James W. Fulbright, Cornelia Weyand Sr. M1666 M1667 Gastrointestinal Symptoms Adversely Affect Quality of Life in Patients with HIV Uzma Siddiqui, Michael A. Poles, Jennifer Leong, Danise Schiliro, Sabeena Ramsetty, Khushbu Chandarana, Edmund J. Bini Gastrointestinal Symptom Profile in Patients with Functional Heartburn Sheila Rodriguez-Stanley, Maggie Wolff, Howard M. Proskin, Philip B. Miner Jr. Urokinase Type Plasminogen Activator(uPA) Is a M1678 Predictor of Malignancy in Cytologic Brushings Obtained at Endoscopic Retrograde Cholangio- Pancreatography (ERCP) Paramvir Singh, Shashi Harvey, James Corasanti, John Gibbs, Rakhee Saxena, Maisie I. Martinick Differentiated Diagnosis of Histology of Pancreatic M1679 Carcinoma Using Ultrasound Contrast Imaging Atsushi Sofuni, Takao Itoi, Daiju Nakayama, Kazuto Nakamura, Hiroko Iijima, Fuminori Moriyasu P-182 Denotes DDW Poster of Distinction

72 POSTER SESSIONS~CLINICAL SCIENCE M1680 M1681 M M1683 M1684 M1685 M1686 M1687 M1688 M1689 M1690 M1691 M1692 Usefulness of Contrast-Enhanced Ultrasonography for the Diagnosis of Pancreatic Tumors Yuko Okamoto, Hirofumi Kawamoto, Etsushi Ishida, Tsuneyoshi Ogawa, Hironon Tanaka, Shinichiro Nakamura, Eiji Matsumoto, Hiroyuki Kobayashi, Kohsaku Sakaguti, Yasushi Shiratoti Selective Inhibition of ikb Degradation by Calpain-1 Inhibitor Ameliorates the Indices of Murine Cerulein- Induced Acute Pancreatitis Ioannis Virlos, Emanuela Mazzon, Ivana Serraino, Christoph Thiemermann, Ajith K. Siriwardena, Salvatore Cuzzocrea Overexpression of Thioredoxin in Transgenic Mice Prevents Severe Acute Pancreatitis Induced with Caerulein and Lipopolysaccharide Shinya Ohashi, Akiyoshi Nishio, Satoko Inoue, Hiroshi Kitamura, Keiichi Kiriya, Hazuki Yoshizawa, Masanori Asada, Hiroyuki Tamaki, Minoru Matsuura, Kimio Kawasaki, Toshiro Fukui, Hiroshi Nakase, Hajime Nakamura, Junji Yodoi, Tsutomu Chiba The Ryanodine Receptor Modulates Pancreatic Zymogen Activation Sohail Z. Husain, Priyajit Prasad, Thomas R. Kolodecik, Michael H. Nathanson, Fred S. Gorelick Heme Oxygenase-1 Induction in Macrophages Protects Mice from Acute Panereatitis Ikuo Nakamichi, Bihui Zhong, M. Bishr Omary Intra-Acinar Cell Activation of Trypsinogen and Redistribution of F-Actin in Response to Supramaximal Caerulein Stimulation of Pancreatic Acini Are Mediated by the Combined Effects of Raising [Ca2+]i and Activating Protein Kinase A George Perides, Anupryia Sharma, Xiahong Tao, Arun Gopal, Brooke Ligon, Michael L Steer Overexpression of Smad6 Deteriorates Pancreatic Injury in Murine Acute Pancreatitis Hayato Nakamura, Mitsuo Tashiro, Hiroshi Asaumi, Yoko Nomiyama, Shiro Watanabe, Makoto Otsuki Dysregnlation of the Calpain-Calpastatin System Plays a Role in the Development of Cerulein-Induced Acute Pancreatitis in the Rat Heike Weber, Ludwig jonas, Saskia Huehns, Peter Schuff- Wemer Overexpression of Glia Maturation Factor (GM'F) in Pancreatic Acinar Cells Increases p38 MAPK Activation, inos Expression and NO Production Asgar Zaheer, Smita A. Zaheer, Ramon Lira, Isaac Samuel The Cholinergic Anti-inflammatory Pathway Mediates Experimental Pancreatitis Severity in Mice David van Westerloo, Ilona Giebelen, Marco Bruno, Alex de Vos, Sandrine Florquin, Kevin Tracey, Tom van der Poll Melatonin Protects Against Acute Obstructive Pancreatitis and Associated Lung Injury in Rats: Role of Neutrophils Afsar Barlas, Hulya Cevik, Sebnem Tekin, Scrap Arbak, Goksel Sener, Cumhur Yegen, Berrak C. Yegen Calcitonin Gene Related Peptide (CGRP): A Key Factor in the Pathogenesis of Acute Necrotizing Pancreatitis Lutz Schneider, Werner Hartwig, Thilo Hackert, Martha- Maria M. Gebhard, Markus W. Buechler, Waldemar Uhl,.lens Werner Gene Expression Profile of Caerulein-Induced Acute Pancreatitis in Mice Ying Hao, Su Yu, Anson Lowe M1693 Influence of Ischemic Precinditioning on the Course of Caerulein-Induced Acute Pancreatitis in Rats Zygmunt Warzecha, Artur Dembinski, Piotr Ceranowicz, Ryszard Sendur, Marcin Dembinski, Jolanta Jaworek, Stanislaw J. Konturek, Wieslaw Pawlik, Jerzy Stachura ASGE Poster Session Authors are required to be present during the Poster Session from 12:00-2:00 pm. AM-5:00 PM Hall F NEW TECHNOLOGY M1694 M1695 M1696 The DAVE Project (Digital Atlas of Video Endoscopy): A New Interuet Based Digital Video Atlas for Educational Purposes Brenna C. Bounds, William R. Brugge, Dan Collier, Peter B. Kelsey Computer-generated, Digital, Multimedia Database for Colonoscopy Piet C. de Groen, Jung Hwan Oh, Wallapak Tavanapong, Johnny S. Wong Development of the White Light-Emitting Diode- Illuminated Digestive Endoscope Hideo Yanai, Hiroki Nakamura, Kiwamu Okita ASGE Poster Session AM-5:00 PM Hall F NEW TECHNOLOGY M1697 M1698 M1699 M1700 M1701 M1702 Evaluation of the Given Patency System in the GI Tract: Results of a Multi-Center Study Guido Costamagna, Cristiano Spada, Gianluca Spera, Maria Elena Riccioni, Livia Biancone, Gouveia Hermano, Juan Manuel Herrerias, Herbert Lochs, Horst Neuhaus, Nageshwar Reddy, Paul Rutgeerts, Stefan Schreiber, Francesco Pallone, Selby Warwick M2A Patency Capsule Prior to Video Capsule Endoscopy in Patients with Morphological Small Bo~ cl Strictures Cristiano Spada, Gianluca Spera, Maria Ek'na Ric~iom, Andrea Tringali, Pietro Familiari, Michcle Malchcsc. Lucio iiiii i ~f-~ Petruzzielto, Livia Biancone, Francesco Pallone. Guicto : :: : :5 ~ Costamagna Feasibility, Safety and Acceptability of String Capsule Endoscopy in Patients with Barrett's Esophagus Francisco C. Ramirez, Masud Shaukat, Rodney Akin> Michele A. Young, David A. Johnson Effects of Temporary Gastric Electrical Stimulation With Endoscopically Placed Electrodes: A Report Of 41 Consecutive Patients Oscar Batista, Robert Schmieg, Thomas L. Abell New Technique of Magnification Pharmaco-endoscopy for Detection of Early Gastric Cancer Katsuro Shirakawa, Tetsuya Nakamura, Yasuo Okura, Takahiro Fujimori, Akira Terano, Hironori Masuyama 170 Wide Angle Colonoscope: Effect on Miss Rates and Efficiency Viju Deenadayalu, Douglas K. Rex 2 ~:-2- i-2-i.~7 i;,~ Denotes DDW Poster of Distinction P-183

73 POSTER SESSIONS--CLINICAL SCIENCE M 0 N D A g MAY 17 M1703 M1704 M1705 M1706 M1707 In vivo Histology of Normal and Diseased Human Colonic Mucosa Using a Fluorescence Confocal Endomicroscope Finlay Macrae, Adrian L. Polglase, Wendy J. McLaren, Elise R. Murr, Peter M. Delaney A Novel Autofluorlesence Imaging Videoendoscopy System for Diagnosis of Esophago-Gastric Cancers Noriya Uedo, Hiroyasu Iishi, Masaharu Tatsuta, Yoshiyuki Hukushima, Koji Higashino, Ryu lshihara, Hiroyuki Narahara Does Chromo Endoscopy in Association with High- Resolution Video Endoscopy Improve Colorectal Adenomas Diagnosis by Colonoscopy? Marie Georges Lapalus, Thierry Helbert, Bertrand Napoleon, Jean Francois Rey, Philippe Houcke, Thierry Ponchon, S. F. Ed M2A Wireless Capsule Endoscopy Versus Enteroclysis; A Prospective Study in 68 Patients with Suspected Small Bowel Disease Periklis Apostolopoulos, Eleftheria Giannakoulopoulou, loannis S. Papanikolaou, Georgios Alexandrakis, X. Papacharalampous, Chrissostomos Kalantzis, Peter Gabriel, Niko/aos Kalantzis Narrow Band Imaging System Could Be a Promising Tool to Detect a Stage 0 Head and Neck Cancer: New Enlightenment to the Endoscopists Manabu Muto, Yasushi Sano, Atsushi Ohtsu, Shigeaki Yoshida ASGE Poster Session AM-5:00 PM Hall F NEW TECHNOLOGY M1708 M1709 M1710 M1711 M1712 Randomized Controlled Evaluation of a Novel Endoscopic Stapling System in an Animal Model for GERD Steven A. Edmundowicz, Juan M. Perrone, Lawrence C. Siegel, James R. Gannoe, Thomas A. Meininger Force Transmission at Flexible Endoscopy with Conventional Endoscopes and Shape Locking Endoscope Guide Catheter Paul Swain, Vahid Sadaat, Rodney Brenneman, Richard Ewers Solutions to Some Difficulties in Sewing at Flexible Endoscopy Paul Swain, Annette Fritscher-Ravens, Sandy Mosse, Per-Ola Park, Keiichi Ikeda, Tim Mills Weight Gain Following Bariatric Surgery Secondary to Staple Line Disruption and Stomal Dilation: Endotherapy Using Sodium Morrhuate to Induce Stomal Stenosis Prevents Need for Surgical Revision Marc F. Catalano, Suku George, Miriam Thomas, Joseph E. Geenen, Thomas Chua En-block Resection of Large Colorectal Laterally Spreading Tumors by Endoscopic Submucosal Dissection Using Flex Knife Atsushi Imagawa, Naohisa Yahagi, Mitsuhiro Fujishiro, Naomi Kakushima, Masashi Oka, Katsuya Kobayashi, Takuhei Hashimoto, Hideyuki Miyoshi, Yoshikazu Moriyama, Masao Omata M1713 M1714 M1715 M1716 M1717 M1718 M1719 M1720 M1721 M1722 Correlation Between Clinical Outcome and Entetyx Implant Shape Glen A. Lehman, Karen Hieston, Lawrence B. Cohen, Colleen D'Souza, James Aisenberg, Robert Ganz, Jan Wakers, T. Raymond Foley, Margaret "Peg" Porter, Karen Wagner, Rebecca Hummel, David Johnson, Tammy L. Stacy, Sheila Friberg, Jacques Deviere, Nathalie Severs, Gregory Haber, Maria Cirocco, Jeffrey Peters, Rosemarie DeMonic, Teresa Rodriguez Treatment Of Esophageal Perforations And Symptomatic Anastomotic Leaks with a New Self-Expandable Plastic Stem Frank Kullmann, Nadia Ratiu, Heiko Rath, Juergen Schoelmerich, Cornelia Gelbmann Graded Esophageal Mucosal Ablation with Cryotherapy and Protective Effects of Submucosal Saline Gottumukkala S. Raju, Ijaz Ahmed, Shu-Yuan Xiao, Douglas Brining, Manoop S. Bhutani, Pankaj J. Pasricha Rotatable Planar Electrodes for Endoscopic Haemostasis Gary Long, Tim Mills, Paul Swain Approximation of Large Mucosal Defects after Endoscopic Mucosal Resection: A New Technique Using a Detachable Snare and Clips Bo-In Lee, Kyu-Yong Choi, Byung-Wook Kim, Hwaug Choi, Se-Hyun Cho, Se-Hee Kim, Woo-Chul Chung, In-Seok Lee, Kang-Moon Lee, Hiun-Suk Chae, Myung-Gyu Choi, In-Sik Chuhg Implantation of a Tubular Membrane in the Small Intestine Brian S. Kelleher, Corbett Stone, Ross rsukashima, Dana Launer Does the Number of Sutures Make a Difference? A Study with a New Device for Endoluminal Treatment of Gastroesophageal Reflux Z. A. Saeed, Anwaar A. Khan, Ahaf Alam, Shahid R. Khalid, Nasir H. Lak, Arshad K Butt Endoscopic Treatment of Esophagogastric Fistulae with an Acellular Matrix Fauze Maluf-Filho, Eduardo Moura, Paulo Sakai, Arthur Garrido Jr., Shinichi Ishioka, Joaquim Gama-Rodrigues, Luiz V. Berti Endoscopic Mucosal Resection of Large Colorectal Lesions Chris Fraser, David Swain, Noriko Suzuki, Brian Saunders Improving Endotherapy - A New Concept for Intraluminal Endoscopic Suturing Arnaldo B. Feitoza, Christopher Gostout, Elizabeth Rajah, Mary Knipschield, Lori Herman, Lawrence Burgart ASGE Poster Session AM-5:00 PM Hall F UPPER GI BLEEDING M1723 Quadruple Therapy ls an Effective Salvage Regimen for Helicobacter Pylori Infection in Patients After Failure of Standard Triple Therapy - Comparison of OMBT 7, 14 Days Regimen - Rok Son Choung, Sang Woo Lee, Hyung Joon Yim, Min Jeong Kim, Yong Sik Kim, Hong Sik Lee, Hoon Jai Chun, Jai Hyun Choi, Ho Sang Ryu, din Hal Hyun M1724 Peptic Ulcer Bleeding, NSAID Use and Helicobacter Pylori Infection: A Prospective Study Evaluating Prevalence and Outcome Monique E. Leerdam van, Dewkoemar Ramsoekh, Erik A. J. Rauws, Alfons A. M. Geraedts, Guido N. Tytgat P-184

74 POSTER SESSIONS~CLINICAL SCIENCE M1725 M1726 M1727 M1728 M1729 M1730 No Influence of Helicobacter Pylori and Previous NSAID/ ASA Therapy on Early Rebleeding Rate in Patients with Peptic Ulcer Bleeding lstvan Racz, Katalin Bircher, Andrea Szabo, Gyula Pecsi, Artur Nemeth Endoscopic 13C-Urea Breath Test for Detection of Helicobacter Pylori Infection After Partial Gastrectomy Yosbihisa Urita, Yoshinori Kikuchi, Kazuo Hike, Naotaka ToriL Eiko Kanda, Hidenori Kurakata, Masahiko Sasajima, Motonobu Ozaki, Kazumasa Miki CagA Positive Flelicobacter Pylori Strains Are Associated with Increased Risk of Peptic Ulcer Bleeding Among NSAID Users. A Multicenter Case-Control Study Michalis Economou, Dimitrios Tzourmakliotis, Spilios Manolakopoulos, Sotiris Bethanis, Christina Bergele, John Lakoumentas, Pantelis Sklavos, Haralambos Milionis, Alexandra Margeli, Evangellos Vogiatzakis, Alec Avgerinos Endoscopic Balloon Dilatation Should Be the Initial Therapy of Choice in Benign Ulcer Related Gastric Outlet Obstruction Vineet Ahuja, Vikram Bhatia, Kaushal Madan, G. Sathyanarayan, Mahesh P. Sharma EMR-Induced Ulcer Healing Rate According to the Duration of Omeprazole Therapy Sun-Young Lee, Jae J. Kim, Jun Haeng Lee, Young-Ho Kim, Poong-Lyul Rhee, Jong Chul Rhee Effect of the Temporary Placement of Stent in Benign Pyloric Stenosis Hyo Jung Kim, Jong-Jae Park, Chang Don Kang, Sung-Joon Lee~ Jin Yong Kim, Jong Eun Yeon, Jae Seon K/m, Kwan Soo Byun, Young-Tae Bak, Chang Hong Lee ASGE Poster Session AM-5:00 PM UPPER GI BLEEDING M1731 M1732 M1733 M1734 Hall F Mortal Convention Center Autoimmune Pancreatitis Can Be Confirmed with Gastroscopy Terumi Kamisawa, Masami Yoshiike, Hitoshi Nakajima, Atsutake Okamoto Diagnosis of Gastric Neoplasms by Newly Developed Auto-fluorescence Imaging Video Endoscopy. Akihiro Namihisa, Tatsuo Ogihara, Akimitsu Ohkawa, Noritomo Nakaniwa, Satoshi Abe, Osamu Kobayashi, Takeshi Terai, Hiroto Miwa, Toshifumi Ohkusa, Nobuhiro Sato Endoscopic Dilation of Gastroenteric Anastomotic Stricture After Gastric Bypass Nelson Heitor Coelho, Julio Pereira Lima, Claudio Rolim Teixeira, Ronaldo Torresini, Rosane Von Muhlen Cirne, Renato Souza, Luis De Carli Clinicopathological Features of Eosinophilic Gastroenteritis Yun-Ju Jo, Nam-In Kim, Young-Sook Park, Tae-Hun Kim, Yeon-Ho Joo ASGE Poster Session AM-5:00 PM Hall F Mortal Convention Center UPPER GI BLEEDING M1735 M1736 M1737 M1738 M1739 M 1740 M1 741 M1742 M 1743 Benefits and Safety of a Novel Double-Balloon Method Enteroscopy in the Detection of Small Intestinal Abnormalities Keigo Mitsui, Sbu Tanaka, Katya Gudis, Tsuguhiko Seo, Masaoki Yonezawa, Kazubiro Nagata, Yoshiaki Shibata, Isao Shinozawa, Atsushi Tatsuguchi, Shunji Fujimori, Teruyuki Kishida, Choitsu Sakamoto Intraoperative Enteroscopy for the Diagnosis of Bleeding from Unknown Origin. A Series of 58 Consecutive Patients Ralf Jakobs, Dirk Hartmann, Georg Bolz, Claus Benz, Dieter Schilling, Erhard Siegel, Uwe Weickert, Juergen F. Riemann Small-Bowel Tumors Diagnosed and Treated by Double- Balloon Endoscopy: Report of Twelve Cases Michiko Iwamoto, Hironori Yamamoto, Keijiro Sunada, Tomonori Yano, Hiroto Kita, Yutaka Sekine, Yoshikazu Hayashi, Hiroyuki Sato, Tomohiko Miyata, Takaaki Iwaki, Hironari Ajibe, Yoshiyuki Kwamura, Kenichi Ido, Kentarou Sugano Double-Balloon Enteroscopy in Patients with Obscure Gastrointestinal Bleeding and/or Chronic Abdominal Pain Andrea D. May, Lars Nachbar, Ahad Wardak, Chriatian Ell Analysis of the Clinical Features and Endoscopic Treatment of Small Intestinal Angiodysplasia Identified by Using Double-Balloon Enteroscopy Hiroyuki Sato, Hironori Yamamoto, Hiroto Kita, Keijiro Sunada, Yoshikazu Hayashi, Tomonori Yano, Michiko t'wamoto, Takaaki Iwaki, Tomohiko Miyata, Yutaka Sekine, Akiko Kuno, Yosiyuki Kwamura, Hironari Ajibe, Kenichi Ido, Kentaro Sugano Clinical Features of Small Intestinal Ulcers Induced by the Nonsteroidal Anti-inflammatory Drugs Identified by the Double-Balloon Enteroscopy Yoshikazu Hayashi, Hironori Yamamoto, Hiroto Kita, Keijiro SLmacla, Hh-O)'Ltki Solo T~n>mo~i "Yan,~ X]i<h:/<, Iwamoto, Yutaka Sekine, Fom,~hiko Mi) ata, ~l:ik,, Ku;> Takaaki Iwaki, Yoshiyuki Ka\~amtu-a. ~tiron~3ri,\ji/~< Kenichi [do, Kentaro Sugano Usefulness of Double-Balloon Total Enleroscopy Ioi Diagnosis and Trealnlent of Small Inlcslinal Disca,,cs Naoki Ohmiya, Ayumu Faguchi. Ma<ahir,~ ~,tnlacla. Kennosuke Shirai, Kenji Kami)'a, Tcl,u,~ klat-uul~ Ma>aya>u O:eki, Nobu)uki Maht<hi, l lh-on,~htt ]\ ~i/.{7~i'/,,<l Masanao NakalnUm, Akihiro Ito, '~o>hiki Hir,~,ka Yasumasa Niwa, Hidemi Goto Diagnostic Yield of Enteroscopy Using a Dedicaled Enteroscope vs. Pediatric Colonoscope Jose G de lx Nh~ia Chri,t,~phcr J c;,,,to<,! [i_,tl, tii!v, _, Mary Knipschield Accessibility of the Double-Balloon Endoscopy to the Anatomically Altered Gastrointestinal Tract by Surgical Procedures Keijiro Sunada, Hironori Yamamoto, Hiroto Kita, Tomonori Yano, Michiko lwamoto, Yoshikazu Hayashi, Hiroyuki Sato, Takaaki Iwaki, Yoshiyuki Kawamura, Hironari Ajibe, Kenichi ldo, Kentaro Sugano P-185

75 r POSTER SESSIONS--CLINICAL SCIENCE ASGE Poster Session AM-5:00 PM Hall F M1756 Re-Evaluation of Trans-Gastrostomic Endoscopy for PEJ Placement: Outcome Parameters William L. Berger, Kia Saeian M O N O A Y MAY 17 UPPER GI BLEEDING Transnasal and Peroral Percutaneous Endoscopic M1744 Gastrostomy by Uhrathin Endoscope in Unsedated Patients: Feasibility, Tolerance,and Complications Mario A. Vitale, Giuseppe villotti, Lucia D'Alba, Maria Assunta De Cesare, Stefano Frontespezi, Fedenco lacopini, Fiammetta Bracci, Giampaolo Iacopini Complications of Radiologically and Endoscopically- M1745 Placed Feeding Gastrostomy Tubes Elizabeth Carey, Shahriar S. Parsa, Eric Huettl, Darius Sorbi A New Infection Prevention K/t for Percutaneous M1746 Endoscopic Gastrostomy (PEGSAS) Can Prevent Peristomal Infection Yutaka Suzuki, Nobuyoshi Hanyu, Katsuhiko Yanaga Efficacy of an Over-tube for Reducing the Risk of M1747 Peristomal Infection After PEG Placement: A Prospective Randomized Comparison Iruru Maetani, Masaki Ikeda, Jun-Ichi Shimura, Takeo Ukita, Yoshihiro Sakai, Masatoshi Yasuda Predicting Outcome in Patients with Percutaneous M1748 Endoscopic Gastrostomy Yakub I. Khan, Ryan Fauble, Michael Piper, Sami Akkary, Catherine Lobocki Randomized Prospective Comparison of Direct M1749 Percutaneous Endoscopic Jejunostomy (DPEJ) vs Percutaneous Endoscopic Gastrostomy with Jejunal Extension (PEG-J) Feeding Tube Placement for Enteral Feeding Mark H. Delegge, Gregory Ginsberg, Steve McClave, James DiSario, Glen Lehman, John Fang Prognostic Factors of One-Month Mortality After M1750 Percutaneous Endoscopic Gastrostomy and Advantages of the Introducer Technique Mitsuhiro Yata, Masami Terada, Hiroyuki Amano, Sadayo Matsumoto, Yukio Tagashira, Junichi Abe, Noriko Yano, Shigeru Kuwayama Laboratory Parameters May Help Predict In-Hospital M1751 Mortality After Percutaneous Endoscopic Gastrostomy (PEG) Uma Kantamneni, Ajit Kokkat, Matio Ricci, HateI Massoumi, Edward Norkus, Nejat Kiyici, Hilary Hertan Use of Propofol in High Risk PEG and Direct PEJ M1752 Placements Kenny Chiu, Korta Yuasa, Maya Gambarin, Alan Kotin, Hans Gerdes, Mark Schatmer, Moshe Shike Effect of Percutaneous Endoscopic Gastrostomy on M1753 Gastro-esophageal Reflux and Gastric Emptying Akihito Iida, Toshihiro Konagaya, Tosihiko Hayakawa, Yasushi Funaki, Akihito Kasahara, Hiroshi Imamura, Shinichi Kakumu, Hiroshi Kaneko Placement of Gastrostomy Tubes in Patients with M1754 Ventriculoperitoneal Shunts Does Not Result in Increased Incidence of Shunt Infection or Decreased Survival Brent Roeder, Adnan Said, Mark Reichelderfer, Deepak Gopal M1755 Complications of Percutaneous Endoscopic Gastrostomy(PEG) and Risk Factors of Peristomal Wound Infection Han-Hyo Lee, Ki-Nam Shim, Jung-Mi Kwon, Jun-Sik Nam, Moon Sun Yeom, Hye-Kyung Jung, Sung-Ae Jung, Sun Young Yi, Doe-Young Kim, Kwon Yoo, I1-Hwan Moon ASGE Poster Session AM-5:00 PM Hall F UPPER GI BLEEDING M1757 M1758 M1759 M1760 M1761 M1762 Endoscopic Papillectomy of the Major Papilla: Results in 55 patients Jennifer J. Telford, Kaumudi Somnay, John R. Saltzman, Peter B. Kelsey, Robert Schapiro, William R. Brugge, Brenna C. Bounds, David L. Car>Locke Duodenal Polypectomy: A High Risk Procedure Gregory Monkewich, Gregory Haber, Paul Kortan, Catherine Streutker, Maria Cirocco, Nancy Bassett, Gabor Kandel, Norman Marcon Palliative Endoscopic Stenting in Malignant Duodenal Obstruction - an Alternative to Surgical Gastroenterostomy? Max Bittinger, Thomas Eberl, Reinhard Scheubel, Reinhard Fleischmann, Helmut Messmann Does Endoscopic Duodenal Stenting Interfere with Previously Inserted Biliary Drainage? Y. D.'Cho, E. R. Kim, Sang Woo Cha, Young Koog Cheon, Y. Kim, J. H. Moon, Y. S. Kim, Cban Sup Shim, Boo Sung Kim Does Endoscopic Duodenal Stenting Interfere with Previously Inserted Biliary Drainage? Y. D. Cho, B. R. Kim, Sang Woo Cha, Y. K. Cheon, Y. Kim, J. H. Moon, Y. S. Kim, Chan Sup Shim, Boo Sung Kim Rendezvous Laparoscopic Endoscopic Resection of Gastroduodenal Stromal Tumors Thomas Abernathy, Lok T. Tio, Frederick C. Finelli ASGE Poster Session AM-5:00 PM Hall F UPPER GI BLEEDING M1763 M1764 M1765 M1766 Long-term Outcome of Argon Plasma Coagulation Therapy in 84 Patients with Bleeding Gastrointestinal Angiomata Simon A. Zanati, Jonathan Cohen, Gregory B. Haber, Gabor Kandel, Paul Kortan, Norman E. Marcon Impact of Multimodal Endoscopic Therapy on Outcome of Acute Upper Gastrointestinal Bleeding (AUGIB): Comparison Between 2002 and in the Treviso Area (North-East Italy) Silvano Loperfido, Ludovica Bellina, Nadia Dal Bo, Sira Bizzotto, Elena Piovesana, Alessandro Caroli, Helena Heras Salvat, Luisa Maifreni, Fabio Monica, Adelina Salvador, Marzia Groppo, Lajos Okolicsanyi Emergency Endoscopy Within 4 Hours Is an Independent Predictive Factor for Reduced Mortality in Patients Presenting with High-R/sk Upper GI Bleeding Tze-Zen Ong, Khay-Guan Yeoh, Khek-Yu Ho Age-Adjusted Hospitalization Rates for Complicated Gastric and Duodenal Ulcers in the US: Have COX-2 Specific Inhibitors and PPIs Made Any Difference? Gurkirpal Singh, Alka Mithal, George Triadafilopoulos P-186

76 POSTER SESSIONSmCLINICAL SCIENCE.M M1768 M1769 M1770 M1771 M1772 M1773 M1774 M1775 M1776 Frequency of Variceal Upper Gastrointestinal Bleeding (UGIB) in Patients with Established Varices Kevin J. Peifer, Gary R. Zuckerman, Mauricio Lisker- Melman, Chandra Prakash Utilisation of the Rockall Score in the Development of a Clinical Pathway for the Management of Non-Variceal Upper Gastrointestinal Bleeding Peter Bampton, Jayne Sandford, Gautam Ramnath, Graeme Young Nasogastric Aspirates Frequently Lead to Erroneous Results and Delay of Therapy in Patients with Suspected UGI Bleeding Asyia Ahmad, Joseph M. Bruno, Robert Boynton, Carlos Leon, Zaid Alnoah, Norman Zitomer, James C. Reynolds The Blatchford Scoring System Do not Predict the Need for Intervention in Upper Gastrointestinal Haemorrhage Virginie Humbert-Sebbagh, Alain Attar, Philippe Le Toumelin, Kouroche Vahedi, Yoram Bouhnik, Groupe des Endoscopistes de garde a' l' AP-HP Evaluation of Endoscopic Treatment of Bleeding Gastroduodenal Ulcers: A 7 year Experience Riadh Bouali, Fawzi Khediri, Slimen Ourak, Amine Hila A Prospective Comparison of Two Endoscopic Clipping Devices in an Animal Model Jeanin E. Van Hooft, Jacques J. Bergman, Paul Fockens Usefulness of the Combined Endoscopic Hemostatic Therapy of Hemoclip Method Following 5% Hypertonic Saline-Epinephrine Injection for the Management of Actively Bleeding Peptic Ulcers Akira Horiuchi, Yoshiko Nakayama, Hideyasu Fujii A Prospective, Randomized Trial of Endoscopic Band Ligation Versus Endoscopic Epinephrine Injection for Actively Bleeding Mallory-Weiss Syndrome Chang-Hwan Park, Wan-Sik Lee, Young-Eun Joo, Hyun-Soo Kim, Sung-Kyu Choi, Jong-Sun Rew, Sei-Jong Kim Procedure of Endoscopic Hemostasis Using a Distal Attachment and Short Clips Against Upper Gastrointestinal Bleeding Naoki Hosoe, Hiroyuki Imaeda, Haruhiko Ogata, Hidekazu Suzuki, Tatsuhiro Masaoka, Manabu Nakashita, Tomoko Tsuda, Hiroyuki Kimura, Koichi Aiura, Yasushi Iwao, Hiroshi Nagata, Koichiro Kumai, Toshifumi Hibi, Hiromasa Ishii The Usefulness of Endoscopic Treatment Compared Hemoclipping with Band Ligation on Active Bleeding of Mallory-Weiss Syndrome Jong Hyun Park, Hiun Suk Chae, Young Seok Cho, Sung Soo Kim, Sok Won Han, Chang Don Lee, in-sik Chung ASGE Poster Session AM-5:00 PM UPPER GI BLEEDING M1777 M1778 Hall F Sensitivity and Inter-Observer Variability for Capsule Endoscopy Image Analysis in a Cohort of Novice Readers Gary Chen, Simon Chan, Clifford Quan, Mary Kalpakian, Tam Tran, Pedram Enayati, Mary Lee Henderson, Gareth Dulai, Ian Arnott, Fumiaki Kitahara, Jeff Gombein, Rome Jutabha Capsule Endoscopy (CE) for Obscure Gastrointestinal Bleeding (OGIB): Does the Yield Decrease with Increased Access? Robert Enns M1779 M1780 M1781 M1782 M1783 M1784 M1785 M1786 M1787 M1788 M 1789 Prospective Controlled Multicentric Trial Comparing Capsule Endoscopy with Intraoperative Enteroscopy: Long Term Results in Patients with Chronic Gastrointestinal Bleeding Harald Schmidt, Dirk Hartmann, Frank Kinzel, Dieter Schilling, Georg Bolz, Peter Reitzig, Henning E. Adamek, Hartmut Hollerbuhl, Klaus Guenther, Klaus Schoenleben, Juergen F. Riemann, Hans J. Schulz The Significance of Capsule Endoscopy (CE) Findings: Results from the CORI Database Douglas O. Faigel, Jennifer Holub, Jonathan Leighton, Glenn Eisen Diagnostic Yield of Video Capsule Endoscopy for Iron Deficiency Anemia Without Overt Gastrointestinal Bleeding Kirk Bernadino, Peter B. Anderson, Steve P. Bensen A Negative Capsule Endoscopy Decreases Resource Utilization in Obscure Gastrointestinal Bleeding Stacey Shapira, Kaja Pluta, Robert Enns The Diagnostic Yield of Capsule Endoscopy in Iron Deficiency Anemia Zvi Fireman, Shosh Frideman Influence of Patient Selection on the Outcome of Capsule Endoscopy in Patients with Chronic Gastrointestinal Bleeding Andrea D. May, Ahad Wardak, Nachbar Lars, Stefanie Retake, Christian Ell Value of the Suspected Blood Indicator in Wireless Capsule Endoscopy Simon A. Zanati, Shou-Jiang Tang, Elena Dubcenco, Gregory Monkewich, Naveen Arya, Gregory B. Haber, Gabor Kandel, Paul Kortan, Norman E. Marcon Automatic Detection of "Red Spots" During Videocapsule Study of the Small Intestine for Unexplained GI Bleeding: Is It Useful? Veronique Michalet, Sabine Roman, Sylvie Radenne, Jean- Louis Gaudin, Jean-Christophe Souquet Second Capsule Endoscopy Examination in Patients with Severe Iron Deficiency Anemia (IDA) Simon Bar-Meir, Moshe Nadler, Olga Barkai, Zvi Fi~cl>,u~ Eytan Scapa, Eytan Bardan, Rami Eliakim Impact of Videocapsule Findings in the Management and Evolution of Unexplained Digestive Bleeding : 50 Patients with 11 Months Follow-up Favre Olivier, Jacob Philippe, Daudet Jacques Evaluation of the Diagnostic Yield of Capsule Endoscopy (CE) in Patients with Obscure Gastrointestinal Bleeding (OGIB) or Unexplained Chronic Iron Deficiency Anemia (UIDA) Juergen R. A. Barnert, Monika Wicker, Max Bittin4ct, Ih~o Eberl, Theo Eberl, Werner Schmidbaur, Hc/mut hlc,,tnann ASGE Poster Session AM-5:00 PM Hall F UPPER GI BLEEDING M 1790 Clinical Outcome of Endoscopic Aspiration Mucosectomy for Early Stage Gastric Cancer Satoshi Tanabe, Wasaburo Koizumi, Katsuhiko Higuchi, Tohru Sasaki, Katsunori Saigenji P-187

77 POSTER SESSIONS--CLINICAL SCIENCE M1791 Recurrence Rate and Risk Factors After Endoscopic Mucosal Resection Dong Seok Lee, Chang Keun Park, Chang Min Cho, Young- Oh Kweon, Chang Hun Yang, Yong Hwan Choi, Sung Kook Kim M1805 Metastatic Tumors to the Stomach: Analysis of 83 Patients Diagnosed by Endoscopy Noriko Sakemura, Takuji Gotoda, Takahisa Matsuda, Hisanao Hamanaka, Ichiro Oda M1792 M1793 Efficacy and Safety of Endoscopic Mucosal Resection Using Precut Method for Treatment of Early Gastric Cancer: Impact of Learning Curve Il Ju Choi, Hee Jin Chang, Hee Sung Kim, Chan Gyoo Kim, Jun Ho Lee, Keun Won Ryu, Young Woo Kim, Jae-Moon Bae The Magnified Endoscopic Finding of an Irregular Microvascular Pattern is a Very Useful Marker for Differentiating Between Gastritis and Gastric Cancer: A Prospective Study Kenshi Yao, Akinon Iwashita, Toshiyuki Matsui, Tsuneyoshi Yao, Keisuke Ikeda, Yasuhiro Takagi, Yosuke Kikuchi, Makoto Yorioka, Kanta Kikuma ASGE Poster Session AM-5:00 PM Hall F UPPER GI BLEEDING M1806 M1807 High Yield of Wireless Capsule Endoscopy in Complicated Celiac Disease Jeanine Daly, Andrea N. Culliford, Moshe Rubin, Peter H. R. Green Capsule Endoscopy: Improving the Transit Time and the Image View Zvi Fireman, Dan Paz Y o N O A g MAY 17 ii M1794 M1795 M1796 M1797 M1798 M1799 M1800 M1801 A New Procedure of En-Bloc Endoscopic Mucosal Resection (EMR) Using Improved Papillotomy Knife (MUCOSECTOME) Kawahara Yoshiro, Shigeatu Fujiki, Yasushi Shiratori The Natural History of Sporadic Duodenal Adenomas and Risk of Synchronous Colonic Adenomas Alexander C. Ford, Olorunda Rotimi, Simon M. Everett Role of Endoscopic Follow-up After Radical Gastrectomy for Stomach Cancer Yong Soo Kim, Tae I1 Kim, Yong Chan Lee, Si Young Song, Won Ho Kim, Jae-Bock Chung, Jin-Kyung Kang, Seung Woo Park The Comparison of Covered and Uncovered Expandable Metal Stents in the Palliation of Malignant Gastric Outlet Obstruction Yu Kyung Cho, Sang-Woo Kim, Se-Hee Kim, Hae-Won Ham In-Seok Lee, Myung Gyu Choi, In-Sik Chung Endoscopic Mucosal Resection (EMR) for Diffuse-Type Mucosal Gastric Cancer Masaya Inoue, Takuji Gotoda, Roy M. Soetikno, Hisanao Hamanaka, Ichiro Oda, Daizo Saito The Effectiveness of Through-the-scope Self-Expandable Metal Stent in Palliation of Malignant Gastrointestinal Obstruction Jeong Seop Moon, Eun Soon Kim, You Sun Kim, Jung Whan Lee, Soo Hyung Ryu Fundamental Endoscopic Findings of Early Gastric Cancer: Importance of Recognition Tatsuo Hirano Endoscopic Submucosal Dissection for Lesions of the Esophago-Gastric Junction and Gastric Cardia Naohisa Yahagi, Mitsuhiro Fujishiro, Naomi Kakushima, Atsushi Imagawa, Katsuya Kobayashi, Takuhei Hashimoto, Masashi Oka, Masao Omata M1808 M1809 M1810 M1811 M1812 M1813 The Capsule Is Not Better and Is Less Cost-Effective Than Conventional Means in Diagnosing Small Bowel Pathology (i.e.: Crohn), but Superior to Enteroclysis in Mapping its Extent George Katsoras, George Grammatopoulos, Charalambos Pavlopoulos, Greg Tsiotos, Konstantinos Dells, Auastasios Grammatopoulos Wireless Capsule Enteroscopy: A Comparison with Entcrography, Push Enteroscopy and Ileo-colonoscopy in the Diagnosis of Small Bowel Crohn's Disease Ervin Toth, Frans-Thomas Fork, Per Almqvist, Cecilia Benoni, Olle Ekberg, Olof Grip, Tombjom Gustafson, Stefan Lindgren, Bodil Ohlsson, Roll Olsson, Klas Sjoberg, Hans Verbaan A Prospective Study of Cox-2 Inhibitors vs NSAIDS Induced Small Bowel Lesions in Asymptomatic Patients Using Video Capsule Endoscopy Jose Luis Vazquez-lglesias, Benito Gonzalez-Conde, Emilio Estevez-Prieto, David Martinez-Ares, Fausto Galdo, Genaro Grana, Antonio Manes Factors That Delay Transit Time of Wireless Capsule Endoscopy Simon Chan, Gary Chen, Mary Kalpakian, Clifford Quan, Mary Lee Henderson, Tam Tran, Pedram Enayati, Gareth Dulai, Ian Arnott, Fumiaki Kitahara, J. Gombein, Rome Jutabha Capsule Endoscopy of the Small Intestine in Graft Versus Host Disease Samuel N. Adler, Harold Jacob, Michael Y. Shapira, Reuven Or, Eliezer Rosenmann Diagnosing Crohn's Disease (CD) of the Small Bowel (SB): Should Capsule Endoscopy (CE) Be Used? CE vs. Other Diagnostic Modalities Elena Dubcenco, Khursheed N. Jeejeebhoy, Rima Petroniene, Arthur H. Zalev, Geoffrey W. Gardiner, Jan E. Irvine, Jeffrey P. Baker M1802 M1803 The Discordance Between Endoscopic Forceps Biopsy and Endoscopic Polypectomy Specimen of Gastric Polyps Dong Ho Lee, Na Young Kim, Jin Wook Kim, Jin Hyeok Hwang, Won Jae Yoon, Hyun Chae Jung, Yong Bum Yoon, In Sung Song Efficacy of Endoscopic Mucosal Resection with Suction in the Treatment of Gastric Adenoma Jae G. Kim, Hyung Joon Kim, Bong Gi Cha, Jae Hyuk Do, Sae Kyung Chang, Sill Moo Park Influence of Collagen in Endoscopic Fluorescence Spectroscopy for Gastric Cancer Brigitte Mayinger, Martin Jordan, Thomas Horbach, Werner Hohenberger, Eckhart Hahn M1814 M1815 Is There a Way to Improve Reading Performance of Wireless Capsule by the Multi-View System Using Maximal Speed of Reading Emmanuel Ben Soussan, Stephane Lecleire, Simon Ramirez, Michel Antonietti, Guillaume Savoye Will a Lesion Seen by Capsule Endoscopy be Amenable to Endoscopic Diagnosis & Treatment? Jose G. de la Mora, Christopher J. Gostout, Elizabeth Rajan, Mary Knipschield M1804 P-188

78 POSTER SESSIONSmCLINICAL SCIENCE ~ M1816 M1817 M1818 M1819 M1820 M1821 M1822 M1823 M1824 M1825 M1826 M1827 M1828 M1829 Should an Entero-CT Scanner (CT) Necessarily Preceed Capsule Endoscopy (CE) Recording When Exploring Patients with Suspected Intestinal Disease (SID)? Michel M. Delvaux, Valerie Laurent, Denis Regent, Gerard Gay A Retrospective Evaluation of Wireless Capsule Endoscopy: Determination of Factors That Influence Transit Time Simon Chan, Jennifer Wang, Jan M. Daniels, Rome Jutabha, Simon K. Lo Interobserver Variability in Wireless Capsule Endoscopy(WCE): 40 Cases of Celiac Disease(CD) Andrea N. Culliford, Moshe Rubin, Jeanine Daly, Peter H. R. Green Tegaserod Decreases Small Bowel Transit Times in Patients Undergoing Capsule Endoscopy Ira J. Schmelkin The Assessment of Wireless Capsule Endoscopy in Paediatrics Mark A. Furman, Maria Mylonaki, Robert Heuschkel, Simon H. Murch, Paul Swain, Annette Fritscher-Ravens, Mike Thomson Reduction of Gastric Transit Time of Video Capsule Endoscopy by Right Lateral Positioning Ritu Sachdev, Patricia Hibberd, Anish Mammen, David R. Cave Is the Angiodisplasia of the Small Bowel a Real Source of Obscure GI Bleeding (OGIB) or Just an Aging Alteration of Small Bowel? Thiago Secchi, Paula Poletti, Ying Tung, Manoel Galvao, Gregorio Feldman, Artur Parada Diagnostic Value of Capsule Endoscopy (CE) in Obscure Digestive Bleeding (ODB) and Effect of Erythromycin Injection Dimitri Coumaros, Laurent Claudel, Patrick Lew, Michel Doffoel Can Capsule Endoscopy Help Differentiate the Aetiology of Indeterminate Colitis? David A. Whitaker, Georgia Hume, Graham U Radford- Smith, Mark N. Appleyard Wireless Capsule Endoscopy vs Small Bowel Enteroclysis in the Detection of Ileal Involvement in Crohn's Disease: A Prospective Controlled Trifil Riccardo Marmo, Gianluca Rotondano, Maria Antonia Bianco, Roberto Piscopo, Livio Cipolletta Analysis of Incomplete Small Bowel Investigation in Capsule Endoscopy Jin Hal Hyun, Bo-Ra Keum, Rok Son Choung, Yong Sik Kim, Yoon Tae Jeen, Hoon Jai Chun, Hong Sik Lee, Soon Ho Um, Sang Woo Lee, Jai Hyun Choi, Chang Duck Kim, Ho Sang Ryu Does Wireless Capsule Endoscopy Have a Role in Evaluating Small Bowel Disorders Other Than Bleeding? Shyam Varadarajulu, Tammy Glenn, Brenda J. Hoffman Capsule Endoscopy (CE): Indications and Results from 100 Consecutive Patients in 2 Tertiary Hospitals in Switzerland Peter Hengstler, Christoph Gubler, Peter Bauerfeind, Christa Meyenberger Influence of Bowel Preparation for Capsule Endoscopy: Quality of Examination and Transit Time Emmanuel Ben Soussan, Michel Antonietti, Stephane Lecleire, Guillaume Savoye M1830 M1831 M1832 M1833 M1834 Randomised Controlled Trial of Polyethyelene Glycol Administration Prior to Capsule Endoscopy Andre Chong, Ashley Miller, Andrew Taylor, Paul Desmond Wireless Capsule Endoscopy in the Diagnosis of Small Intestinal Neoplasms in Patients with Gastrointestinal Polyposis Syndromes. Preliminary Results of a Comparative Study with Barium Contrast Series Alfredo Mata, Josep Llach, Antoni Castells, Maria Pellise, Gloria Fernandez-Esparrach, Angels Gines, Josep Maria Rovira, Josep Maria Pique, Josep Maria Bordas Capsule Endoscopy for the Evaluation of Small Bowel: Great Expectations Still Waiting to Be Met Giacomo C. Sturniolo, Vincenza Di Leo, Maria G. Vettorato, Renata D'Inca' A Pilot Study of Capsule Endoscopy Reading by a Nurse Endoscopist Shai Friedland, Kuan Wu, Roy M. Soetikno Indications Versus Findings in Capsule Endoscopy (CE) Davendra Ramkumar SSAT Poster Session AM-5:00 PM Hall F BILIARY: CLINICAL M1835 M1836 M1837 M1838 M1839 M1840 M1841 M1842 Is Patient Selection the Cause of Higher Complication Rates Observed with Open Common Bile Duct Exploration (CBDE) Relative to ERCP? Edward H. Livingston, Robert V. Rege Prospective Evaluation of Endoscopic Ultrasonography in the Diagnosis of Biliary Microlithiasis in Patients with Normal Conventional Ultrasonography Seyed Amir Mirbagheri, Mehdi Mohamadnejad, Jafar Nasiri, Reza Malekzadeh, Ramin Ghadimi, Farhad Zamani, Shahin Merat lsf-fdg PET in the Evaluation of Patients with Gallbadder Cancer Carlos U. Corvera, Timothy Akhurst, Ronald P. DeMatteo, Michael D'Angelica, Leslie Blumgart, William Jarnagin, Yuman Fong What Do We Do in Elderly Patients Presenling with Common Bile Ducts Stones and a Gallbladder In Situ? The Economic hnplications of a "Wait and See" Approach Versus Cholecystectomy Britt Drake, Miguel R. Arguedas, blcredith Kilg~,t<' (]tztll,.- M. Wilcox Access- Related Complications After Laparoscopic Cholecystectomy: The Risk is in the Closed Tcchnique Rocio Anula-Fernandez, Maria Jesu> Pena bolia, Ct i>tllq.l Pardo-Martinez, Julio M. Mayol, Jesus A Fcnqanclc: IZcprc,,, The Usefulness of Bovine Pericardium in the Repair of Full Thickness Bile Duct Defects: An Experimental Study in Pigs Ronald Matteotti, Ahmad Assalia, Kazuki Ueda, Michel Gagner The Effect of Successful Hepatico-Jejunostomy on Bile and Its Flow - a One-Year Experimental Study Johanna Laukkarinen, Pierce Chow, Juhani Sand, Sidney Yu, S. Somanesan, Irene Kee, In Chin Song, Teck Hin Ng, Isto Nordback The United States Experience with Conversion from Laparoscopic to Open Cholecystectomy Edward H. Livingston, Robert V. Rege Denotes DDW Poster of Distinction P-189

79 POSTER SESSIONS--CLINICAL SCIENCE ~ i%: M 0 N D A Y MAY 17 SSAT Poster Session AM-5:00 PM Hall F COLON-RECTAL: CLINICAL M1843 M1844 M1845 M1846 M1847 M1848 M1849 MI850 M1851 M1852 M1853 M1854 M1855 Duration of Postoperative Ileus After Elective Colectomy is Correlated to Surgical Specialization Pascal Gervaz Avoidance of Mechanical Bowel Preparation for Elective Colorectal Surgery with Primary Anastomosis: A Meta- Analysis Pascal Bucher, Bernadette Mermillod, Claudio Soravia, Pascal Gervaz, Philippe Morel Resection of Isolated Pelvic Recurrences After Colorectal Surgery- the Fox Chase Cancer Center Experience Leonard R. Henry, Elin Sigurdson, Eric A. Ross, Gary M. Freedman, Andre Konski, John P. Hoffman Intraperitoneal Hyperthel~aRf[~J~therapy for Peritoneal qarcw,,d~sd~l~&and Outcomes JF~~i~l[~t~" J~vlc~ar ty, Joseph Kuhn, Tammy Rate of Incisional Hernia After Laparoscopic-assisted Colectomy- Early Experience Joseph C. Muller, Andrea Ferrara, Paul R. Williamson, Sergio W. Larach, Joseph T. Gallagher, Samuel DeJesus, Robert A. Campbell Assessment of Quality of Life in Patients with Rectal Cancer Treated with Preoperative Radiotherapy: A Longitudinal Prospective Study Pascal Gervaz, Abdelkarim S. Allal, Arnaud Roth, Philippe Morel Multioption Strategy to Maximize Therapeutic Outcome in Patients with Liver Metastases from Colorectal Cancer Giovanni Begossi, Ihor Ponomarenko, Charu Taneja, Heidi Alien, Martha Jamison, Harold J. Wanebo Full-Thickness Transanal Excision Can Achieve Excellent Oncologic Outcomes in Low T1 and T2 Rectal Cancers John Lee, Ingrid M. Meszoely, John P. Hoffman Neoadjuvant Short-Term Radiotherapy of Low Rectal Cancer Is an Important Risk Factor for Anastomotic Breakdown After Surgery Bernhard Egger, Ivo Winiger, Richard Greiner, Daniel Candinas Efficacy of Fibrin Glue Sealing in the Treatment of Anal Fistulas Marco Sailer, Dominik Stehle, Dieter Bussen, Martin Fein Long-Term Results of Laparoscopic Rectopexy for Rectal Prolapse Tilman T. Zittel, Tobias Merle, Christian Leitz, Markus Kueper, Mario H. Mueller, Michael Kasparek, Joerg Glatzle, Ekkehard C. Jeble, Martin E. Kreis Posterior Rectal Resection (Altemeier Operation) for the Treatment of Rectal Prolapse or Rectocele Tobias Meile, Martin E. Kreis, Rosemarie Hinninghofen, Ilona Stabenow, Eckehard C. Jehle, Tilman T. Zittel Embolization as First-Line Therapy for Diverticulosis- Related Massive Lower Gastrointestinal Bleeding: Evidence from a Meta-Analysis Amit Khanna, Nicole Hodgson, Steven J. Ognibene, Leonidas G. Koniaris M1856 M1857 M1858 M1859 M1860 M1861 M1862 M1863 M1864 M1865 M1866 M1867 M1868 M1869 Comparison of the Cecal Intubation Rate and Diagnostic Yield of Screening Colonoscopy Performed by Gastroenterologists and Surgeons Christopher S. Lee, Shahzad Iqbal, Samera Vaseer, Jennifer Northrop, Christine T. Bang, Andrew Y. Lo, Albert D. Min Neoadjuvant Radiochemotherapy for Patients with Locally Advanced Rectal Caner Leads to Impairment of the Anal Sphincter Joerg Theisen, Werner K H. Kauer, Ludwig Schmid, J. Ruediger Siewert, Hubert Stein Patterns of Use of Nasogastric Intubation and Early Nutrition in the Management of Postoperative Ileus Henrik Kehlet, Markus Buechler, Robert Beart Jr., Russell Williamson Quality of Life and Functional Results After Colon Pouch Reconstruction Susanne Dorothea Otto, Martin Kruschewski, Hubert G. Hotz, Christoph T. Germer, Heinz J. Buhr De-epithelialization with Seton Placement or Curettage Is Effective Primary Therapy for Perianal Fistulae in Crohn's Disease Richard Tilson, Sonia Friedman, Ronald Bleday, Peter Banks, Rie Ookubo, Elizabeth Breen Is the Current Practice of Mechanical Bowel Preparation in Colonic Surgery Evidence Based? Henrik Kehlet, Markus Buechler, Robert Beart Jr., Russell Williamson Increased Use of Lower Anterior Resection for Rectal Cancer in Veterans Jessica A. Davila, Neena S. Abraham, Linda Rabeneck, David H. Berger, Hashem B. E1-Serag Examining the Feasibility of Laparoscopic Radical Proctosigmoidectomy for the Chemoirradiated Rectal Cancer John H. Marks, Ulana B. Kawun, Wajdi Hamdan, Mohammed Mohiuddin, Gerald Marks Criteria for Ileostomy Closure in Patients with Anastomotic Sinus Tracts Tina Wong, Avo Artinyan, Robert W. Beart Jr. Quality of Life After Ileal Pouch-Anal Anastomosis: Comparison of Patients with Familial Adenomatous Polyposis and Ulcerative Colitis Philippe Wuthrich, Pascal Gervaz, Philippe Morel Rectal Complications After Modern Radiation for Prostate Cancer: A Colorectal Surgical Challenge David W. Larson, Kristin Chrouser, Suzan Sweat, Tonia Young-Fadok, Heidi Nelson Effect of Immunosuppressive Therapy on Septic Complications in Ulcerative Colitis Martin J. Utzig, Anton J. Kroesen, Heinz J. Buhr Quality of Life After Proctocolectomy and Ileal Pouch- Anal Anastomosis (IPAA) in Patients with Ulcerative Colitis (UC) Michael S. Kasparek, Jana Conrad, Joerg Glatzle, Mario H. Mueller, Ekkehard C. Jehle, Martin E. Kreis, Tilman T. Zittd Outpatient Treatment of Diverticulits Jeffrey Friedman, Jose R. Monzon, Johelen Carleton, Steven J. Heneghan P Denotes DDW Poster of Distinction

80 POSTER SESSIONS--CLINICAL SCIENCE SSAT Poster Session AM-5:00 PM Hall F ESOPHAGEAL: CLINICAL CD147 and Matrix Metalloproteinase 2 Protein M1870 Expressions as Significant Prognostic Factors in Esophageal Cell Carcinoma Yoshio Ishibashi, Nobuyoshi Hanyu, Koji Nakada, Yutaka Suzuki, Nobuo Omura, Kyosuke Yamada, Kiyoshi Ohkawa, Mitsuyoshi Urashima, Makio Kawakami, Katsuhiko Yanaga Improved Prognosis of Resected Esophageal Cancer M1871 Over a Twenty Year Period Hubert J. Stein, Marcus Feith, Bjom Bruecher, Holger Bartels, J. Ruediger Siewert Upper Esophageal Sphincter (UES) Myotomy, but Not M1872 Botulinum Toxin Injection Is an Effective Treatment for Severe Oropharyngeal Dysphagia: Final Results of a Phase-2 Study Giovanni Zaninotto, Mario Costantini, Christian Rizzetto, Rosario Marchese Ragona, Stefano Masiero, Lorenza Caregaro-Negrin, Lorenzo Zanetti, Giampietro Feltrin, Chiara Briani, Loredana Nicoletti, Michela Costantino, Sandro Polidoro M1873 M1874 M1875 M1876 M1877 M1878 M1879 M1880 M1881 Characterizing Normal Pharyngeal Reflux Using Impedance and 24hr Pharyngeal ph Monitoring Federico Cuenca-Abente, Brant K. Oelschlager, John A. Isch, Carlos A. Pellegrini Symptomatic Outcome After Laparoscopic Antireflux Surgery in GERD Patients with Respiratory Symptoms Ruxandra Ciovica, Michael Gadenstatter, Christoph Neumayer, Rudolph Poinmer, Gerhard Schwab FDG-PET is Not Suitable for Staging of Early Cancers of the Upper Gastrointestinal Tract Burkhard H. A. yon Rahden, Hubert J. Stein, Hinrich Wieder, Wolfgang A. Weber, Katja Ott, Mario Sarbia, J. Ruediger Siewert lntra-operative Measurement of Gastroesophageal Junction Distensibility (GEJD): A New Technique to Evaluate Fundoplication "Tightness" Shailesh Bajaj, Jianxiang Liu, Osamu Kawamura, Candy Hofmann, Tanya Rittmann, Ronald C. Arndorfer, Gary Korus, Dennis Blom, Reza Shaker Trends in the Management of Esophageal Carcinoma: Treatment Practices of 595 Esophageal Surgeons Charles Kirn, Clifford Deveney, John Davis, Ashley Vernon, Kevin Reavis, Brett Sheppard, John G. Hunter, Blair A. Jobe Characterization of Dysphagia Using Multichannel Intraluminal Impedance Leena Khaitan, Sandy Everett, C. Daniel Smith BarrettEsophagus: Antireflux Procedure or Proton Pump Inhibitors Brian K. Zebrowski, Syed Shah, Aaron Sasson, John Dibaise, Jane L. Meza, Dmitry Oleynikov Experiences with Endoscopic Surveillance of Patients with Barrett's Esophagus in a Single German Center Burkhard H. A. von Rahden, Hubert J. Stein, Marcus Feith, Jakob Meyen, Mario Sarbia, J. Ruediger Siewert Extent of Resection for Esophagogastric Junction Siewert's Type II Tumors: Esophagectomy or Gastrectomy? Results From a Multicentre French Study Alain Sauvanet, Christophe Mariette, Jean-Pierre Triboulet, Pascal Thomas, Patrick Lozach, Philippe Segol, Emmanuel Tiret, Jean-Robert Delpero, Denis Collet, Joel Leborgne M1882 M1883 M1884 M1885 M1886 M1887 M1888 M1889 M1890 M1891 M1892 M1893 M1894 M1895 M1896 Progression of Barrett's Esophagus in the German Registry Karl-Hermann Fuchs, Martin Fein, Joern Maroske Obesity, Reflux, and Hiatal Hernia: Is There a Connection? Nahid Hamoui, Jeffrey Hagen, Anand Tamhankar, Gary Anthone, Peter Crookes Impedance As a Measure of Esophageal Motility in Patients with GERD Federico Cuenca-Abente, Brant K. Oelschlager, John A. Isch, Carlos A. Pellegrini Predictors of Impaired Quality of Life in Patients with Gastroesophageal Reflux Disease Martin Fein, Joern Maroske, Marco Sailer, Karl-Hermann Fuchs Optimal Therapy for Barrett Esophagus with High Grade Dysplasia: Cost-Effectiveness Analysis Mark K. Ferguson, Amy E. Durkin, Irving Waxman Prognostic Factors in Barretts Carcinoma: Results of 500 Consecutive Resected Adenocarcinoma of the Distal Esophagus Marcus Feith, Hubert J. Stein, J. Ruediger Siewert Impact of Laparoscopic Nissen Fundoplication with Mesh-hiatoplasty on Esophageal Body Motility: A Prospective Randomized Trial Frank A. Granderath, Ursula M. Schweiger, Thomas Kamolz, Rudolph Pointner Obesity Is Not a Contraindication to Laparoscopic Nissen Fundoplication Matthew J. D'Alessio, Dean Arnaoutakis, Natalie Giarelli, Alexander S. Rosemurgy li Extent of Preoperative Staging in Esophageal Cancer to Prevent Futile Explorative Surgery Henderik L. Van Westreenen, Pierre A. M. Heeren, Hendrik M. van Dullemen, Eric J. van der Jagt, Pieter L. Jager, Henk Groen, John T. H. M. Plukker Dysphagia After Laparoscopic Antireflux Surgery Is Related to Inadequate Hiatal Closure and Not to Fundoplication Frank A. Granderath, Ur, u]a M. Schwci.<eh T/>~ma, Kamolz, Rudolph Pointner Distal Esophageal Adenocarcinmna: Does Prescn(c of Barrett's Mucosa Matter? Giuseppe PoFtale, Jefftey H Petet-~, Ta>ha A. K Gandalllihardja, Chih Chcng ll>ieh, Ch<~din Ih.~.,~. Daniel Va]lboehmer, Anand P. Tanqhankar. ]clhc',.'~ Hagen, Cedric G Brenmer= Tom R Dc'NiccstcE + The Type of Reflux Does No! lnllucncc tl~e Ottlt,ltne o[ Nissen Fundoplication Carlos A Galvani Maria V C;or~dnel-, \lnlco (7 I~,/tt Patient Perception of a Clinical Pathway for Laparoscopic Foregut Surgery Lorenzo E. Ferri, Christopher Andrew, Liane Feldman, Robert Baird, Donna Stanbridge, Gerald Fried Does Vagotomy During Complex Esophageal Surgery Affect Clinical Outcomes? Todd A. Woltman, Brant K. Oelschlager, Kyle Yamamoto, Juan-David Parra, Carlos A. Pellegrini A Single Institution Experience with Robotically Assisted Transhiatal Total Esophagectomy Garth Jacobsen, N. J. Espat, Federico Moser, Adam Goldstein, Jason Harris, Robert Berger, Santiago Horgan Denotes DDW Poster of Distinction P-191

81 POSTER SESSIONS--CLINICAL SCIENCE M1897 Computer Enhanced Rob~ti I K~[gery Eliminates Esophageal p~f~t~ l~gli~l~ Myotomy W. ~. ~~Jb~fnd~n, Garth Jacobsen, Mark A. T~l~r~, ~r~iggo Horgan SSAT Poster Session AM-5:00 PM Hall F M O N 0 A Y MAY 17 M1898 M1899 M1900 M1901 M1902 M1903 M1904 M1905 M1906 M1907 M1908 M1909 Radiofrequency Energy Delivery to the Lower Esophageal Sphincter in Patients with Recurrent Reflux After Antireflux Surgery: Can Redo Surgery Be Avoided? David A. McClusky III, Leena Khaitan, Vickie A. Swafford, C. Daniel Smith T-tube Drainage to Create a Controlled Esophageal Fistula in the Face of Delayed Diagnosis of Esophageal Perforation James Huang, Hasan Batirel, Richard Gilbert, Jeanne Lukanich, Yolonda Colson, Michael Chang, Philip Linden, " Raphael Bueno, Steven Mentzer, David Sugarbaker, Michael Jaklitsch Esophagotomy During Laparoscopic Heller Myotomy Can Not Be Predicted by Application of Preoperative Therapies and Does Not Influence Long-term Outcome Steven Rakita, Mark Bloomston, Natalie Giarelli, Desiree Villadolid, Candace Kalipersad, Haim Pinkas, Emmanuel Zervos, Alexander Rosemurgy Laparoscopic Nissen Fundoplication: Robotic Assisted (AESOP) vs. Human Assisted. A Comparative Study Sergio Rojas-Ortega, Daniel Arizpe, Amelia Morales, Rachid Cesin, Gerardo Reed, Cris Gomez Dysphagia After Laparoscopic Partial Fundoplication Maud Lindeboom, Jan Ringers, Jan-Willem Straathof, Pieter van Rijn, Peter Neijenhuis, Ad Masclee Delayed Diagnosis of Esophageal Cancer Due to Psychiatric Disorders Jed Robinson, Jason Andrus, Brian Diggs, Blair Jobe Outcome and Quality of Life After Esophagectomy for High Grade Dysplasia and Intramucosal Cancer Robert J. Moraca, Donald E. Low Epidemiology of Symptoms Suggestive of Gastroesophageal Reflus Disease: A Pupulation-Based Study in South China Minhu Chen II, Lishou Xiong, Huixin Chen, Angao Xu, Pin-Jin Hu Cause and Treatment of Epiphrenic Diverticula Piero M. Fisichella, Maria V. Gorodner, Carlos A. Galvani, Lawrence W. Way, Marco G. Patti Geographical Variation in Patient Expectations of Antireflux Surgery Vic Velanovich, Thomas Kamolz, Rudolph Poinmer, Sandro Contini Laparoscopic Paraesophageal Hernia Repair (LPEHR) with Biomaterial Mesh: Favorable Short Term Results Omar K. Danner, George M. Eid, Samer G. Mattar, Ramesh C. Ramanathan, Giselle G. Hamad, Daniel R. Cottam, Philip R. Schauer Non-Reflux Related Pain After Laparoscopic Nissen Fundoplication Andrew J. Duffy, Nancy J. Hogle, Arnon Lambroza, Dennis L. Fowler HEPATIC: CLINICAL M1910 M1911 M1912 M1913 M1914 M1915 M1916 The Oncologic Effect of the TissueLink TM Device on Liver Surface Tumors and Positive Margins Eric S. Weiss, Michael S. Torbenson, Tracy J. Wanner, Barbara M. McGee, Jean F. Geschwind, Michael A. Choti Hepatic Resection for Incidentaloma Chi-Leung Liu, Sheung-Tat Fan, Chung-Mau Lo, See-Ching Chan, Irene O. Ng, Wai-Kuen Tso, John Wong Robotically-Assisted Radiofrequency Ablation of Liver Tumors: Comparison with Standard Manual Techniques Michael M. Awad, Stephen B. Solomon, Alex Patriciu, Dan Stoianovici, Michael A. Choti In-vivo Evaluation of a Simulation Model for Interstitial Tumor Ablation by Radiofrequency Thermotherapy in Porcine Liver with Normal and Interrupted Hepatic Perfusion Joerg P. Ritz, Christoph [sbert, Andre Roggan, Kai Lehmann, Heinz Buhr Surgical Drainage Following Hepatic Resection: A Prospjective Series from a Single Institution Jonathan B. Koea, All Almeida, John McCall NASH Risk Factors in Bariatrie Patients Ronatd E. Moore, Atul K. Madan, Mark A. Carlson, Constantine T. Frantzides Laparoscopic Radiofrequency Ablation of Resectable Colorectal Metastases to the Liver Jason T.H Wong, Paul Hansen SSAT Poster Session AM-5:00 PM Hall F PANCREAS: CLINICAL M1917 M1918 M1919 M1920 Randomized Controlled Trial of Pylorus-preserving Whipple Versus Duodenum-preserving Pancreatic Head Resection in Chronic Pancreatitis Frank Makowiec, Hartwig Riediger, Ulrich T. Hopt, Ulrich Adam Risk Factors and Outcomes in Patients with Postpancreaticoduodenectomy Pancreaticocutaneous Fistula John W. Lin, John L. Cameron, Charles J. Yeo, Taylor A. Sohn, Keith D. Lillemoe Endothelial Injury Induced by Neutrophils in Acute Pancreatitis. Role of Endothelins Lourenilson J. Souza Sr., Ellena C. Paulino, Nilza A. T. Molan, Sonia Jancar, Jose Eduardo M. Cunha, Marcel C. C. Machado Pancreaticoduodenectomy for Pancreatic Adenocarcinoma: Impact of Margin Status on Pattern of Failure and Survival Chandrajit P. Raut, Charles R. Scoggins, Karen R. Cleary, Eddie K. Abdalla, Jean-Nicolas Vauthey, Jeffrey E. Lee, Peter W. T. Pisters, Douglas B. Evans M1921 The Utility of Endoscopic Ultrasound in the Surgical Management of Pancreatic Disorders Paul Vietzen, Shawn Mallery, Rebecca Lai, Timothy Sielaff P-192 Denotes DDW Poster of Distinction

82 . v POSTER SESSIONSICLINICAL SCIENCE M1922 Mt923 M1924 M1925 M1926 M1927 : M1928 M1929 M1930 M1931 M1932 M1933 M1934 M1935 Patterns of Orexigenic Hormones Following Pancreaticoduodenectomy Syed A. Abroad, Jeffrey B. Matthews, S. Park, Andrew M. Lowy, A. Balasubramaniam, Sulaiman Sheriff Clinical Utility of 18-FDG PET in the Diagnosis and Management of Nonpancreatic Periampullary Neoplasms Cosimo Sperti, Claudio Pasquali, Andrea Ferronato, Domenico Decet, Franca Chierichetti, Guido Liessi, Sergio Pedrazzoli Relevance and Classification of Pancreatic Leackage After Pancreatic Resection Frank Makowiec, Ulrich Adam, Hartwig Riediger, Ulrich T. Hopt Influence of Hospital Volume on Mortality in Pancreaticodnodenectomy: A Meta-Analysis Tjarda Van Heek, Rutger Van Geenen, Steve De Castro, Huug Obertop, D. J. Gouma Single Institution Series of 20 Solid-psendopapillary Tumors of the Pancreas T. D. Dixon, Debashish Bose, John L. Cameron, Michael J. Zinner, Keith D. Lillemoe Expression of CEACAM6 Is a Factor of Independent Prognostic Significance in Pancreatic Cancer Evan Matros, Mark S. Duxbury, Mark Redston, Stanley W. Ashley, Edward E. Whang A Clinically-Relevant Definition of Pancreatic Anastomotic Leak After Pancreticoduodenectomy L. W. Traverso, Keita Wada, Hiroyuki Shinchi Stapled Laparoscopic Cystgastrostomy -- A Series with 15 Cases Andrew Hindmarsh, Grace Lee, Michael P. N. Lewis, Michael Rhodes Perioperative Blood Transfusion and Disease-Site Other Than Pancreas Are Associated with Increased Incidence of Clinically Relevant Intra-Abdominal Abscess Formation Following Pancreaticoduodenectomy Margo Shoup, Pamela Hodul, Gerard V. Aranha Role of Endoscopic Ultrasound in the Evaluation of Indeterminate Pancreatic Lesions R. Walsh, M. Ghanamah, N. Brown, Gregory Zuccaro, John Dumot, John Vargo Pharmacokinetics of the Antineoplastic Drug Mitomycin C in Regional Chemotherapy Using the Aortic Stop Flow Technique in Advanced Pancreatic Carcinoma Frank Meyer, Karsten Ridwelski, Reinhard Grote, Jens Martens-Lobenhoffer, Hans Lippert Long-term Results of Surgical Treatment of Vater Ampulla Neoplasms Pascal Bucher, Chassot Gilles, Durmischi Imer, Pascal Gervaz, Philippe Morel Long Term Safety of Laproscopic Distal Pancreatectomy in Patients with Cystic Neoplasms of the Pancreas Tauqeer Ahmad, Fazylov Rafeal, Theodoros Daskalakis, Joel Horovitz, Richard Lazarro, Jerzy Macura, Scott Tenner Systematic Appraisal of the Management of the Major Vascular Complications of Pancreatitis Srinivasan Balachandra, Ajith K. Siriwardena SSAT Poster Session AM-5:00 PM SMALL BOWEL: CLINICAL M1936 M1937 M1938 M1939 M1940 M1941 M1942 M1943 Hall F Immunosuppression with Steroids or Azathioprine Does not Increase the Postoperative Complication Rate in Abdominal Surgery for Crohn's Disease Markus Kueper, Andrei Dinescu, Mario H. Mueller, Tobias Meile, Michael Kasparek, Joerg Glatzle, Ekkehard C. Jehle, Martin E. Kreis, Tilman T. Zittel Analysis of 7090 Carcinoids in Florida Over the Last 20 Years Sarah E. Snell, Nicole Hodgson, Leonidas G. Koniaris, Alan S. Livingstone, Dido Franceschi Palliative Stenting for Late Malignant Gastric Outlet Obstruction Shannon J. Graewin, Kulwinder S. Dua, Attila Nakeeb, Beth A. Erickson, Paul S. Ritch, Henry A. Pitt A Modern Approach to Managing Superior Mesenteric Venous Thrombosis Gregory J. McKenna, Gabriel Gondolesi, Sharif Ellozy, Alfio Carrocio, Michael Harris, Michael Wayne, Manuel Rodriguez-Davalos, Sander Florman, Sukru Emre, Myron Schwartz, Thomas Fishbein Predictive Factors for Surgery in Pediatric Patients with Crohn's Disease Neera Gupta, Melvin B. Heyman, Stanley A. Cohen, Traci Clemons, Terry Smith, Benjamin D. Gold, Barbara Kirschner, George D. Ferry, Robert N. Baldassano, Harland S. Winter, Michael Durant, Pat L. Fain, Pediatric IBD Consortium Adenocarcinomas of the Jejunum and Ileum: A 25-year Experience Mustafa M. Ugurlu, Oktar Asoglu, D. D. Potter Jr., Sunni A. Barnes, W. Scott Harmsen, John H. Donohue Preoperative TNF-~ Antagonist Therapy in the Surgical Management of Crohn's Disease Hari Nathan, Mark A. Talamini, Susan Gearhart, Mary Harris, Theodore Bayless Small Bowel Adenocarcinoma: Presentation, Treatment. Pathologic Characteristics, and Outcome Edward C. McCarron, John Gibbs, Mar\van Fal<ih, I IL~,! Nava, Ashwani Rajput SSAT Poster Session AM-5:00 PM H~III F Morial Co~vcnthm ccn&'~ STOMACH: CLINICAL M M1945 M1946 Marked Improvement of Gastroesophageal Reflux Disease (GERD), Hypertension, Diabetes, and Other Obesity-Related Illnesses Following a Gastric Rcstriclion Procedure with an Adjustable Band Elizabeth E. Half, Mary F. Hewitt, Amir Onn, Hadar Spivak Clinical Response to Long-Term Gastric Electrical Stimulation in Patients with Post-Surgical Gastroparesis Jameson Forster, Zhiyue Lin, Irene Sarosiek, Paul Wetzel, Richard W. McCallum Contrast Studies After Weight Loss Surgery Do Not Change Outcome: An Analysis of 378 Patients Mercedeh Baghai, Edward Lin, Kent R. Van Sickle, Vickie A. Swafford, C. Daniel Smith Denotes DDW Poster of Distinction P-193

83 POSTER SESSIONS--CLINICAL SCIENCE M1947 M1948 M1949 M1950 M1951 M1952 M1953 M1954 M1955 Treatment of Stomal Stricture After Gastric Bypass with Endoscopic Balloon Dilation Ramon E. Rivera, Sreenivasa Jonnalagadda, J. Chris Eagon Laparoscopic Gastric Bypass Results in Decreased Medication Costs With-in Six Months Jon Gould, Michael Garren, James Starling Patterns of Lymph Node Metastasis in Early Gastric Cancer and Impact on Survival Carlos E. Jacob, Claudio Bresciani, Sidney Arazawa, Renato Iwashita, Rodrigo Perez, Kyioshi lryia, Bruno Zilberstein, Joaquim Gama-Rodrigues Extreme Obesity and Outcomes Following Long-Limb Gastric Bypass Thomas H. Magnuson, Michael Schweitzer Complications and Reoperations After Laparoscopic Adjustable Gastric Banding for Morbid Obesity - Long Term Follow-Up from an FDA Trial Center Stewart E. Rendon, Kenneth G. MacDonald Jr., William H. H. Chapman, Bobbie L. Price Pyloroplasty with Fundoplication in the Treatment of Combined Gastroesophageal Reflux Disease and Bloating Vic Velanovich Adjustable Gastric Banding as an Outpatient Procedure; A Multi-Institutional Experience of 700 Successful Patients Santiago Horgan, Garth Jacobsen, Federico Moser, Fernando Elli, Jason Harris, Adam Goldstein, Robert Berger, Jaime Ponce Prognostic Factors in the Management of Primary Gastric Lymphoma Heriberto Medina-Franco, Santos Soto-Germes, Carlos Chan, Carmen Lome-Maldonado Vitamin and Iron Metabolism in Morbid Obese Patients Before and Two Years After Gastric Band Jocelyn P. M Roduit, Natascha Potoczna, Thomas Ricklin, Rudolf Steffen, Thomas Krech, Fritz F. Horber M1962 M1963 M1964 M1965 M1966 M1967 M1968 M1969 M1970 Perioperative and Postoperative Changes in Body Composition After Gastrectomy Teruo Kiyama, Takashi Tajiri, Akira Tokunaga, Toshiro Yoshiyuki, Takashi Mizutani, Takeshi Okuda, Itsuro Fujita, Shunji Kato, Adrian Barbul Laparoscopic Resection of Gastric Stromal Tumonrs -- A Series with 29 Cases Andrew Hindmarsh, Brendan Koo, Grace Lee, Michael P. N. Lewis, Michael Rhodes Metabolic Syndrome and the Impact of Gastric Bypass Surgery Thomas H. Magnuson, Michael Schweitzer, Jon Vogel Management of Failed Adjustable Gastric Banding Rudolf Steffen, Laurent Biertho, Ruth Branson, Natascha Potoczna, Thomas Ricklin, Grazyna Piec, Fritz F. Horber Age Alone Does Not Have a Significant Impact on the Short and Long-Term Outcome of Roux-En-Y Gastric Bypass for Morbid Obesity loannis S. Raftopoulos, Julie A. Ercole, Anthony O. Udekwu, James D. Luketich Sr., Anita P. Courcoulas The Preoperative Serum Albumin Level Is a Prognostic Indication for Adenocarcinoma of the Gastric Cardia Yung-Chang Lien, Chih-Cheng Hsieh, Yu-Chung Wu, Han- Shui Hsu, Wen-Hu Hsu, Liang-Shun Wang, Min-Hsiung Huang, Biing-Shiun Huang Analysis of Volume and Gastric Acid Output from 2 and 15 Minute Infusions of Intravenous Pantoprazole (IVP) from a Pilot Study in Peri-operative Setting joseph R. Pisegna, Robyn Karlstadt, David S. Oh, Brian G. Field, Jay Graepel Characterization of Psychosoeial and Demographic Predictors of Outcome Following Weight Loss Surgery Mercedeh Baghai, Leena Khaitan, David A. McClusky ii1, Nana Gletsu, Stanley L. Chapman, C. Daniel Smith Laparoscopic Gastric Bypass in High Risk Patients Paul A. Thodiyil, Tomasz Rogula, Samer G. Mattar, George M Eid, William F. Gourash, Philip R. Schauer D A MAY; 17 M1956 M1957 M1958 Extended Resection for Locally Advanced Siewert's Type III Esophagogastric Junction Cancer: Is It Advisable? Results From a French Multicentre Study Christophe Mariette, Main Sauvanet, Jean-Pierre Triboulet, Pascal Thomas, Patrick Lozach, Philippe Segol, Emmanuel Tiret, Jean-Robert Delpero, Denis Collet, Joel Leborgne Realistic Expectations: Outcomes After Roux En Y Gastric Bypass in Patients with BMI over 55 Steven P. Bowers Jr., Donald H. Jenkins, Joel E. Goldberg Peroral Endoscopic Repair of Staple-Line Dehiscence in Roux-en-Y Gastric Bypass: A Less Invasive Approach Christopher C. Thompson, David L. Car>Locke, John Saltzman, David Lautz, James Slattery, Malcolm K. Robinson M1971 M1972 M1973 Depressive Illness and History of Sexual Assualt in Bariatric Surgery Canidates Steven C. Poplawski, Patricia Choban, Jon Schram, Jessica Schram, Nikhil Dhurandhar Relationship Between Dyspeptic Symptoms, Gastroduodenal Lesions and H. Pylori Infection in Chronic Renal Failure Gerardo Nardone, Alba Rocco, Maria Fiorillo III, Marisa Del Pezzo, Giovanni Autiero, Antonietta Lambiase, Gabriele Budillon, Bruno Cianciaruso Surgical Pathology and Outcome of Gastrointestinal Stromal Tumors of the Stomach Yi-Qian N. You, Imran Hassan, Roman Shyyan, Florencia G. Que, Thomas C. Smyrk, John H. Donohue iili M1959 M1960 Influence of Preoperative Age, Gender and BMI on Outcome After Gastric Banding Thomas Ricklin, Rudolf Steffen, Ruth Branson, Natascha Potoczna, Grazyna Piec, Fritz F. Horber The Impact of Bariatric Surgery on Resident Operative Experience Jon D. Vogel, Michael A. Schweitzer, Thomas H. Magnuson M1974 M1975 Revision Versus First-Time Gastric Bypass in Morbid Obesity - a 5-year Follow-up Study Sven Gustavsson, Magnus Sundbom, Anita Ohlin Preoperative Nutritional Status of Patients Undergoing Roux-en-Y Gastric Bypass for Morbid Obesity Tihesha Wilson, Victoria Drake VI, Toni Colarusso, Louis Flancbaum M1961 Resolution of Diabetes After Roux en Y Gastric Bypass Carson D. Liu, Christina Y. Kim M1976 Incidental Gastroscopic Findings in Morbidly Obese Patients Dan Azagury, Gilles Chassot, Jean-Marc Dumonceau, Philippe Morel, Olivier Huber P Denotes DDW Poster of Distinction

Physiological processes in the GI tract:

Physiological processes in the GI tract: Gastrointestinal physiology for medical students General principal of gastrointestinal function Motility, nervous control and blood circulation Physiological processes in the GI tract: Motility Secretion

More information

ulcer healing role 118 Bicarbonate, prostaglandins in duodenal cytoprotection 235, 236

ulcer healing role 118 Bicarbonate, prostaglandins in duodenal cytoprotection 235, 236 Subject Index Actin cellular forms 48, 49 epidermal growth factor, cytoskeletal change induction in mucosal repair 22, 23 wound repair 64, 65 polyamine effects on cytoskeleton 49 51 S-Adenosylmethionine

More information

CASTLE HOWARD EVENT 2018

CASTLE HOWARD EVENT 2018 Castle Howard Triathlon Saturday 21st July 2018 Castle Howard Triathlon Sunday 22nd July 2018 The 'Brideshead Revisited' Sprint Plus - 800m/46km/8km Includes Macmillan Cancer Support Charity Place Race

More information

Genome-wide association study of esophageal squamous cell carcinoma in Chinese subjects identifies susceptibility loci at PLCE1 and C20orf54

Genome-wide association study of esophageal squamous cell carcinoma in Chinese subjects identifies susceptibility loci at PLCE1 and C20orf54 CORRECTION NOTICE Nat. Genet. 42, 759 763 (2010); published online 22 August 2010; corrected online 27 August 2014 Genome-wide association study of esophageal squamous cell carcinoma in Chinese subjects

More information

INTRODUCTION TO GASTROINTESTINAL FUNCTIONS

INTRODUCTION TO GASTROINTESTINAL FUNCTIONS 1 INTRODUCTION TO GASTROINTESTINAL FUNCTIONS 2 Learning outcomes List two main components that make up the digestive system Describe the 6 essential functions of the GIT List factors (neurological, hormonal

More information

IL-12 family members in experimental colitis. Markus F. Neurath I. Medical Clinic Johannes Gutenberg-University Mainz, Germany

IL-12 family members in experimental colitis. Markus F. Neurath I. Medical Clinic Johannes Gutenberg-University Mainz, Germany IL-12 family members in experimental colitis Markus F. Neurath I. Medical Clinic Johannes Gutenberg-University Mainz, Germany IBD - Pathogenesis Genetic Predisposition Bacterial Antigens Activation of

More information

Gastrointestinal Anatomy and Physiology. Bio 219 Napa Valley College Dr. Adam Ross

Gastrointestinal Anatomy and Physiology. Bio 219 Napa Valley College Dr. Adam Ross Gastrointestinal Anatomy and Physiology Bio 219 Napa Valley College Dr. Adam Ross Functions of digestive system Digestion Breakdown of food (chemically) using enzymes, acid, and water Absorption Nutrients,

More information

For more information about how to cite these materials visit

For more information about how to cite these materials visit Author: John Williams, M.D., Ph.D., 2009 License: Unless otherwise noted, this material is made available under the terms of the Creative Commons Attribution Non-commercial Share Alike 3.0 License: http://creativecommons.org/licenses/by-nc-sa/3.0/

More information

Gastrointestinal Motility 2: Intestinal and Colonic Motility Jack Grider, Ph.D.

Gastrointestinal Motility 2: Intestinal and Colonic Motility Jack Grider, Ph.D. Gastrointestinal Motility 2: Intestinal and Colonic Motility Jack Grider, Ph.D. OBJECTIVES: 1. Contrast the types of motility in the small intestine. 2. Describe the neural circuits that mediate peristalsis.

More information

Overview of digestion

Overview of digestion Key concepts in Digestion. Overview of digestion introduction to the GI system Prof. Barry Campbell Cellular & Molecular Physiology e-mail: bjcampbl@liv.ac.uk http://pcwww.liv.ac.uk/~bjcampbl DIGESTION

More information

Soft palate elevates, closing off the nasopharynx. Hard palate Tongue Bolus Epiglottis. Glottis Larynx moves up and forward.

Soft palate elevates, closing off the nasopharynx. Hard palate Tongue Bolus Epiglottis. Glottis Larynx moves up and forward. The Cephalic Phase Chemical and mechanical digestion begins in the mouth Saliva is an exocrine secretion Salivary secretion is under autonomic control Softens and lubricates food Chemical digestion: salivary

More information

12/10/2009. Department of Pathology, Case Western Reserve University. Mucosal Cytokine Network in IBD

12/10/2009. Department of Pathology, Case Western Reserve University. Mucosal Cytokine Network in IBD Cytokine-Mediated Inflammation in IBD Theresa T. Pizarro Department of Pathology, Case Western Reserve University Mucosal Cytokine Network in IBD Andoh, et al., 2008 1 Interleukin-1 (IL-1) Family Cytokine

More information

Section Coordinator: Jerome W. Breslin, PhD, Assistant Professor of Physiology, MEB 7208, ,

Section Coordinator: Jerome W. Breslin, PhD, Assistant Professor of Physiology, MEB 7208, , IDP Biological Systems Gastrointestinal System Section Coordinator: Jerome W. Breslin, PhD, Assistant Professor of Physiology, MEB 7208, 504-568-2669, jbresl@lsuhsc.edu Overall Learning Objectives 1. Characterize

More information

17 th International Conference of the Inflammation Research Association: Wednesday AM (Day 4) September 9-13, 2012

17 th International Conference of the Inflammation Research Association: Wednesday AM (Day 4) September 9-13, 2012 17 th International Conference of the Inflammation Research Association: Wednesday AM (Day 4) September 9-13, 2012 The Sagamore Resort, Bolton Landing, NY, USA The following report includes highlights

More information

University of Buea. Faculty of Health Sciences. Programme in Medicine

University of Buea. Faculty of Health Sciences. Programme in Medicine Faculty of Health Sciences University of Buea Wednesday, 28 th January 2009 Time: 8 00-10 00 Programme in Medicine MED 303 (Gastrointestinal Physiology) EXAMS (2008-2009) Identify the letter of the choice

More information

Genetics. Environment. You Are Only 10% Human. Pathogenesis of IBD. Advances in the Pathogenesis of IBD: Genetics Leads to Function IBD

Genetics. Environment. You Are Only 10% Human. Pathogenesis of IBD. Advances in the Pathogenesis of IBD: Genetics Leads to Function IBD Advances in the Pathogenesis of IBD: Genetics Leads to Function Pathogenesis of IBD Environmental Factors Microbes Scott Plevy, MD Associate Professor of Medicine, Microbiology & Immunology UNC School

More information

Overview of digestion or, gut reactions - to food

Overview of digestion or, gut reactions - to food Key concepts in Digestion. Indigestion module Overview of digestion or, gut reactions - to food Prof. Barry Campbell Gastroenterology Cellular & Molecular Physiology e-mail: bjcampbl@liv.ac.uk http://pcwww.liv.ac.uk/~bjcampbl

More information

Virchow s Hypothesis lymphorecticular infiltration of cancer reflected the origin of cancer at sites of inflammation

Virchow s Hypothesis lymphorecticular infiltration of cancer reflected the origin of cancer at sites of inflammation Virchow s Hypothesis 1863 lymphorecticular infiltration of cancer reflected the origin of cancer at sites of inflammation Barrett s esophagus/ Esophageal adenocarcinoma PSC / Cholangiocarcinoma Viral hepatitis

More information

Gender Differences in Autoimmune Diseases

Gender Differences in Autoimmune Diseases //9 Impact of Gender on the Pathogenesis of Crohn s Disease Theresa T. Pizarro Department of Pathology, CWRU Gender Differences in Autoimmune Diseases n Autoimmune diseases affect ~.7-. million people

More information

renoprotection therapy goals 208, 209

renoprotection therapy goals 208, 209 Subject Index Aldosterone, plasminogen activator inhibitor-1 induction 163, 164, 168 Aminopeptidases angiotensin II processing 64 66, 214 diabetic expression 214, 215 Angiotensin I intrarenal compartmentalization

More information

NASH Bench to Bedside

NASH Bench to Bedside NASH Bench to Bedside October 2006 Anna Mae Diehl, M.D. Gastroenterology Division Duke University NonAlcoholic Fatty Liver Disease Common ~1/4-1/3 1/3 US adults Outcome highly variable Course indolent

More information

Exosomes as a. Novel Therapeutic Approach to Gastrointestinal Diseases Rebecca Murray APRN, FNP, CDE

Exosomes as a. Novel Therapeutic Approach to Gastrointestinal Diseases Rebecca Murray APRN, FNP, CDE Exosomes as a Novel Therapeutic Approach to Gastrointestinal Diseases Rebecca Murray APRN, FNP, CDE Endocrine Nurse Practitioner Institute for Hormonal Balance Orlando, FL Medical Director Ward-Murray

More information

What part of the gastrointestinal (GI) tract is composed of striated muscle and smooth muscle?

What part of the gastrointestinal (GI) tract is composed of striated muscle and smooth muscle? CASE 29 A 34-year-old man presents to his primary care physician with the complaint of increased difficulty swallowing both solid and liquid foods. He notices that he sometimes has more difficulty when

More information

Subject Index. hypothalamic-pituitary-adrenal axis 158. Atherosclerosis, ghrelin role AVP, see Arginine vasopressin.

Subject Index. hypothalamic-pituitary-adrenal axis 158. Atherosclerosis, ghrelin role AVP, see Arginine vasopressin. Subject Index Acromegaly, somatostatin analog therapy dopamine agonist combination therapy 132 efficacy 132, 133 overview 130, 131 receptor subtype response 131, 132 SOM30 studies 131, 132 ACTH, see Adrenocorticotropic

More information

Innate immune regulation of T-helper (Th) cell homeostasis in the intestine

Innate immune regulation of T-helper (Th) cell homeostasis in the intestine Innate immune regulation of T-helper (Th) cell homeostasis in the intestine Masayuki Fukata, MD, Ph.D. Research Scientist II Division of Gastroenterology, Department of Medicine, F. Widjaja Foundation,

More information

Subject Index. Bcl-2, apoptosis regulation Bone marrow, polymorphonuclear neutrophil release 24, 26

Subject Index. Bcl-2, apoptosis regulation Bone marrow, polymorphonuclear neutrophil release 24, 26 Subject Index A1, apoptosis regulation 217, 218 Adaptive immunity, polymorphonuclear neutrophil role 31 33 Angiogenesis cancer 178 endometrium remodeling 172 HIV Tat induction mechanism 176 inflammatory

More information

Overview of digestion or, gut reactions - to food

Overview of digestion or, gut reactions - to food 1 Key concepts in Digestion. Indigestion module Overview of digestion or, gut reactions to food Prof. Barry Campbell Gastroenterology Cellular & Molecular Physiology email: bjcampbl@liv.ac.uk http://pcwww.liv.ac.uk/~bjcampbl

More information

ACTIVATION OF T LYMPHOCYTES AND CELL MEDIATED IMMUNITY

ACTIVATION OF T LYMPHOCYTES AND CELL MEDIATED IMMUNITY ACTIVATION OF T LYMPHOCYTES AND CELL MEDIATED IMMUNITY The recognition of specific antigen by naïve T cell induces its own activation and effector phases. T helper cells recognize peptide antigens through

More information

ROLE OF TGF-BETA SIGNALING IN PIK3CA-

ROLE OF TGF-BETA SIGNALING IN PIK3CA- ROLE OF TGF-BETA SIGNALING IN - DRIVEN HEAD AND NECK CANCER INVASION AND METASTASIS 1,2 Sophia Bornstein, 3 Jingping Shen, 3 Jacob Minor, 3 Frank Hall, 3 Fang Zhang, 4 Sherif Said, 4 Xiao-Jing Wang, 1

More information

Special Issue on Pain and Itch

Special Issue on Pain and Itch Special Issue on Pain and Itch Title: Recent Progress in Understanding the Mechanisms of Pain and Itch Guest Editor of the Special Issue: Ru-Rong Ji, PhD Chronic pain is a major health problem world-wide.

More information

Getting into the weed: the endocannabinoid system of the gut-brain axis in energy homeostasis. Keith Sharkey

Getting into the weed: the endocannabinoid system of the gut-brain axis in energy homeostasis. Keith Sharkey Getting into the weed: the endocannabinoid system of the gut-brain axis in energy homeostasis Keith Sharkey Department of Physiology & Pharmacology University of Calgary Dr. Keith Sharkey Financial Interest

More information

2.4 Autonomic Nervous System

2.4 Autonomic Nervous System 2.4 Autonomic Nervous System The ANS regulates visceral activities normally outside the realm of consciousness and voluntary control: Circulation. Digestion. Sweating. Pupillary size. The ANS consists

More information

Role of nuclear bile acid receptor FXR in intestinal bacterial overgrowth and translocation

Role of nuclear bile acid receptor FXR in intestinal bacterial overgrowth and translocation Role of nuclear bile acid receptor FXR in intestinal bacterial overgrowth and translocation Antonio Moschetta University of Bari, Consorzio Mario Negri Sud, Santa Maria Imbaro (Chieti), Italy www.negrisud.it

More information

Cell-Derived Inflammatory Mediators

Cell-Derived Inflammatory Mediators Cell-Derived Inflammatory Mediators Introduction about chemical mediators in inflammation Mediators may be Cellular mediators cell-produced or cell-secreted derived from circulating inactive precursors,

More information

Overview of Gastroenterology

Overview of Gastroenterology Harvard-MIT Division of Health Sciences and Technology HST.121: Gastroenterology, Fall 2005 Instructors: Dr. Jonathan Glickman Overview of Gastroenterology Gastroenterology Made Really Simple! Food Waste

More information

Animal Models to Understand Immunity

Animal Models to Understand Immunity Animal Models to Understand Immunity Hussein El Saghire hesaghir@sckcen.be Innate Adaptive immunity Immunity MAPK and NF-kB TLR pathways receptors Fast Slow Non-specific Specific NOD-like receptors T-cell

More information

Why would fatty foods aggravate the patient s RUQ pain? What effect does cholecystokinin (CCK) have on gastric emptying?

Why would fatty foods aggravate the patient s RUQ pain? What effect does cholecystokinin (CCK) have on gastric emptying? CASE 28 A 43-year-old woman presents to the emergency department with the acute onset of abdominal pain. Her pain is located to the right upper quadrant (RUQ) and radiates to the right shoulder. She reports

More information

Amniotic fluid stem cells provide considerable advantages in epidermal. regeneration: B7H4 creates a moderate inflammation

Amniotic fluid stem cells provide considerable advantages in epidermal. regeneration: B7H4 creates a moderate inflammation Amniotic fluid stem cells provide considerable advantages in epidermal regeneration: B7H4 creates a moderate inflammation microenvironment to promote wound repair Qing Sun 1, +, Fang Li 1, +, Hong Li 2,

More information

T-cell activation T cells migrate to secondary lymphoid tissues where they interact with antigen, antigen-presenting cells, and other lymphocytes:

T-cell activation T cells migrate to secondary lymphoid tissues where they interact with antigen, antigen-presenting cells, and other lymphocytes: Interactions between innate immunity & adaptive immunity What happens to T cells after they leave the thymus? Naïve T cells exit the thymus and enter the bloodstream. If they remain in the bloodstream,

More information

T-cell activation T cells migrate to secondary lymphoid tissues where they interact with antigen, antigen-presenting cells, and other lymphocytes:

T-cell activation T cells migrate to secondary lymphoid tissues where they interact with antigen, antigen-presenting cells, and other lymphocytes: Interactions between innate immunity & adaptive immunity What happens to T cells after they leave the thymus? Naïve T cells exit the thymus and enter the bloodstream. If they remain in the bloodstream,

More information

Human Lung Cancer Pathology and Cellular Biology Mouse Lung Tumor Workshop

Human Lung Cancer Pathology and Cellular Biology Mouse Lung Tumor Workshop Human Lung Cancer Pathology and Cellular Biology Mouse Lung Tumor Workshop Jan 7 th and 8 th, 2014 Brigitte Gomperts, MD University of California, Los Angeles Lung Structure and Function Airway Epithelial

More information

Cytokines, adhesion molecules and apoptosis markers. A comprehensive product line for human and veterinary ELISAs

Cytokines, adhesion molecules and apoptosis markers. A comprehensive product line for human and veterinary ELISAs Cytokines, adhesion molecules and apoptosis markers A comprehensive product line for human and veterinary ELISAs IBL International s cytokine product line... is extremely comprehensive. The assays are

More information

Cathepsin S Inhibitors for the Treatment of Inflammatory Bowel Disease. Therapeutic Area Partnerships Presentation.

Cathepsin S Inhibitors for the Treatment of Inflammatory Bowel Disease. Therapeutic Area Partnerships Presentation. Inhibitors for the Treatment of Inflammatory Bowel Disease Therapeutic Area Partnerships Presentation November 29, 2012 Cathepsin Cysteine Proteinases Fibrosis Cathepsin O Cathepsin B Cathepsin C Cathepsin

More information

PBS Class #2 Introduction to the Immune System part II Suggested reading: Abbas, pgs , 27-30

PBS Class #2 Introduction to the Immune System part II Suggested reading: Abbas, pgs , 27-30 PBS 803 - Class #2 Introduction to the Immune System part II Suggested reading: Abbas, pgs. 15-25, 27-30 Learning Objectives Compare and contrast the maturation of B and T lymphocytes Compare and contrast

More information

Inflammation in the clinic

Inflammation in the clinic Inflammation in the clinic Stephen T. Holgate MRC Clinical Professor of Immunopharmacology ILSI Europe Workshop, Seville, May 14-15 2012 The immune system acts in four general ways to ensure host defence

More information

Principles of Genetics and Molecular Biology

Principles of Genetics and Molecular Biology Cell signaling Dr. Diala Abu-Hassan, DDS, PhD School of Medicine Dr.abuhassand@gmail.com Principles of Genetics and Molecular Biology www.cs.montana.edu Modes of cell signaling Direct interaction of a

More information

Extracellular and Intracellular Signaling

Extracellular and Intracellular Signaling Extracellular and Intracellular Signaling Edited by James D. Adams, Jr. School of Pharmacy, University of Southern California. Los Angeles. CA, USA Keith K. Parker Department of Biomedical and Pharmaceutical

More information

Central tolerance. Mechanisms of Immune Tolerance. Regulation of the T cell response

Central tolerance. Mechanisms of Immune Tolerance. Regulation of the T cell response Immunoregulation: A balance between activation and suppression that achieves an efficient immune response without damaging the host. Mechanisms of Immune Tolerance ACTIVATION (immunity) SUPPRESSION (tolerance)

More information

Mechanisms of Immune Tolerance

Mechanisms of Immune Tolerance Immunoregulation: A balance between activation and suppression that achieves an efficient immune response without damaging the host. ACTIVATION (immunity) SUPPRESSION (tolerance) Autoimmunity Immunodeficiency

More information

Mechanisms of Tumor Suppressor Gene Demethylation in Colon Cancer by Berries

Mechanisms of Tumor Suppressor Gene Demethylation in Colon Cancer by Berries Mechanisms of Tumor Suppressor Gene Demethylation in Colon Cancer by Berries Li-Shu Wang, PhD Assistant Professor Department of Medicine Medical College of Wisconsin Cancer Center Ten Leading Cancer Types

More information

Development of Carcinoma Pathways

Development of Carcinoma Pathways The Construction of Genetic Pathway to Colorectal Cancer Moriah Wright, MD Clinical Fellow in Colorectal Surgery Creighton University School of Medicine Management of Colon and Diseases February 23, 2019

More information

EMPEROR'S COLLEGE MTOM COURSE SYLLABUS HERB FORMULAE I

EMPEROR'S COLLEGE MTOM COURSE SYLLABUS HERB FORMULAE I COURSE DESCRIPTION The first of three courses in the Herb Formulae series. These courses can be taken in any order. The Herb Formulae series analyzes the functions, ingredients, and properties of approximately

More information

Necrotizing Enterocolitis: The Role of the Immune System

Necrotizing Enterocolitis: The Role of the Immune System Necrotizing Enterocolitis: The Role of the Immune System Patricia Denning, M.D. Associate Professor in Pediatrics Division of Neonatology Emory University School of Medicine What is NEC? What is NEC? Necrotizing

More information

CONFIRMATION DOCKET REPORT- 4/4/2019 RONALD B. KING

CONFIRMATION DOCKET REPORT- 4/4/2019 RONALD B. KING 1950215 BUTTLES MONTOYA, CYNTHIA 1853063 CAIN EDWARDS, KURT W. & REBECCA 1950206 CAIN MACKEY, MICHAEL & REINA, MACKEY 1950209 CAIN MENDEZ, MARICELA RODARTE 1852885 CAIN PAEZ, DANIEL R. 3/25/19 san_report_mattercalendardocket

More information

Meeting to Transform. Networking Events. Help Transform IBD Through Collaborative Solutions in Patient-centric Care. Submit An Abstract

Meeting to Transform. Networking Events. Help Transform IBD Through Collaborative Solutions in Patient-centric Care. Submit An Abstract be sent December 4. Late-breaking abstracts will be accepted from November 28-December 8. Fellows, nurses, and advanced practice providers are encouraged to submit abstracts for oral presentation and be

More information

Discussion & Conclusion

Discussion & Conclusion Discussion & Conclusion 7. Discussion DPP-4 inhibitors augment the effects of incretin hormones by prolonging their half-life and represent a new therapeutic approach for the treatment of type 2 diabetes

More information

Supplementary Figure 1.

Supplementary Figure 1. Supplementary Figure 1. Increased expression of cell cycle pathway genes in insulin + Glut2 low cells of STZ-induced diabetic islets. A) random blood glucose measuers of STZ and vehicle treated MIP-GFP

More information

Antigen Presentation and T Lymphocyte Activation. Abul K. Abbas UCSF. FOCiS

Antigen Presentation and T Lymphocyte Activation. Abul K. Abbas UCSF. FOCiS 1 Antigen Presentation and T Lymphocyte Activation Abul K. Abbas UCSF FOCiS 2 Lecture outline Dendritic cells and antigen presentation The role of the MHC T cell activation Costimulation, the B7:CD28 family

More information

Gamma-aminobutyric acid (GABA) treatment blocks inflammatory pathways and promotes survival and proliferation of pancreatic beta cells

Gamma-aminobutyric acid (GABA) treatment blocks inflammatory pathways and promotes survival and proliferation of pancreatic beta cells Gamma-aminobutyric acid (GABA) treatment blocks inflammatory pathways and promotes survival and proliferation of pancreatic beta cells Gérald J. Prud homme, MD, FRCPC Keenan Research Centre for Biomedical

More information

Review Questions: Janeway s Immunobiology 8th Edition by Kenneth Murphy

Review Questions: Janeway s Immunobiology 8th Edition by Kenneth Murphy Review Questions: Janeway s Immunobiology 8th Edition by Kenneth Murphy Chapter 11 (pages 429-460): Dynamics of Adaptive Immunity prepared by Kelly von Elten, Walter Reed National Military Medical Center,

More information

EMPEROR'S COLLEGE MTOM COURSE SYLLABUS HERB FORMULAE II

EMPEROR'S COLLEGE MTOM COURSE SYLLABUS HERB FORMULAE II COURSE DESCRIPTION The second of three courses in the Herb Formulae series. Categories covered in Formulae II include the Tonify Qi and Blood, Regulate Qi, Invigorate the Blood, Stop Bleeding, Stabilize

More information

Motilin. Edited by. Zen Itoh. Gastrointestinal Laboratories College of Medical Technology Gunma University Maebashi, Japan

Motilin. Edited by. Zen Itoh. Gastrointestinal Laboratories College of Medical Technology Gunma University Maebashi, Japan Motilin Edited by Zen Itoh Gastrointestinal Laboratories College of Medical Technology Gunma University Maebashi, Japan Academic Press, Inc. Harcourt Brace Jovanovich, Publishers San Diego New York Berkeley

More information

CORRELATION BETWEEN SURVIVIN OVEREXPRESSION AND CLINICO-PATHOLOGICAL FEATURES OF INVASIVE CERVICAL CANCER: A META-ANALYSIS

CORRELATION BETWEEN SURVIVIN OVEREXPRESSION AND CLINICO-PATHOLOGICAL FEATURES OF INVASIVE CERVICAL CANCER: A META-ANALYSIS Acta Medica Mediterranea, 2018, 34: 1091 CORRELATION BETWEEN SURVIVIN OVEREXPRESSION AND CLINICO-PATHOLOGICAL FEATURES OF INVASIVE CERVICAL CANCER: A META-ANALYSIS HUI-RONG LI 1, JI-LI BAI 2*, RUI XU 2,

More information

Northumberland Special Olympics Regional Gala 2013 at Blyth Sports Centre RESULTS

Northumberland Special Olympics Regional Gala 2013 at Blyth Sports Centre RESULTS Northumberland Special Olympics Regional Gala 2013 at Blyth Sports Centre RESULTS EVENT 1 Male Pick Up Object 1 Robbie Strachan Northumberland 1:00.00 2 Paul Clarkson Northumberland 1:05.00 John Hall Northumberland

More information

Lymphoid System: cells of the immune system. Answer Sheet

Lymphoid System: cells of the immune system. Answer Sheet Lymphoid System: cells of the immune system Answer Sheet Q1 Which areas of the lymph node have most CD3 staining? A1 Most CD3 staining is present in the paracortex (T cell areas). This is towards the outside

More information

They all do it! What?

They all do it! What? They all do it! What? Defensins: the endogenous antibiotics of body surfaces Wehkamp J et al. (2005) Mechanisms of Disease: defensins in gastrointestinal diseases Nat Clin Pract Gastroenterol Hepatol 2:

More information

Inflammatory bowel disease (IBD) is a chronic, relapsing. Role of Neuropeptides in Inflammatory Bowel Disease BASIC SCIENCE REVIEW

Inflammatory bowel disease (IBD) is a chronic, relapsing. Role of Neuropeptides in Inflammatory Bowel Disease BASIC SCIENCE REVIEW BASIC SCIENCE REVIEW Role of Neuropeptides in Inflammatory Bowel Disease Kara J. Gross, MD,*, and Charalabos Pothoulakis, MD* Abstract: Inflammatory bowel disease (IBD) is a chronic, relapsing condition

More information

2011 International Conference of Inflammation, Cancer and Metabolic Disorders Program

2011 International Conference of Inflammation, Cancer and Metabolic Disorders Program Friday, November 4 th, 2011 09:00-09:30 Registration 09:30-09:40 Welcome & Opening Remarks Kenneth K. Wu, M.D., Ph.D. Fu-Tong Liu, M.D., Ph.D. Plenary Lecture I Chair: Kenneth K. Wu, M.D., Ph.D. 09:40-10:40

More information

Chapter 20 The Digestive System Exam Study Questions

Chapter 20 The Digestive System Exam Study Questions Chapter 20 The Digestive System Exam Study Questions 20.1 Overview of GI Processes 1. Describe the functions of digestive system. 2. List and define the four GI Processes: 20.2 Functional Anatomy of the

More information

CONTENTS. Preface... xii

CONTENTS. Preface... xii CONTENTS Preface... xii 1. Autocrine Transformation: Cytokine Model... 1 James A. McCubrey, Xiao-Yang Wang, Paul A. Algate, William L. Blalock and Linda S. Steelman Abstract... 1 Cytokine Regulation of

More information

Molecular and Cellular Basis of Immune Protection of Mucosal Surfaces

Molecular and Cellular Basis of Immune Protection of Mucosal Surfaces Molecular and Cellular Basis of Immune Protection of Mucosal Surfaces Department of Biologic & Materials Sciences School of Dentistry University of Michigan Ann Arbor, Michigan 48109-1078 1 Image quality

More information

Purinergic Neuron-to-Glia Signaling in the Enteric Nervous System Dr. Brian D. Gulbransen

Purinergic Neuron-to-Glia Signaling in the Enteric Nervous System Dr. Brian D. Gulbransen 1 Assistant Professor Neuroscience Program and Department of Physiology Michigan State University East Lansing, Michigan USA The requirement to nourish and sustain an organism, as well as to defend it

More information

5. Which component of the duodenal contents entering the stomach causes the most severe changes to gastric mucosa:

5. Which component of the duodenal contents entering the stomach causes the most severe changes to gastric mucosa: Gastro-intestinal disorders 1. Which are the most common causes of chronic gastritis? 1. Toxic substances 2. Chronic stress 3. Alimentary factors 4. Endogenous noxious stimuli 5. Genetic factors 2. Chronic

More information

Tolerance 2. Regulatory T cells; why tolerance fails. Abul K. Abbas UCSF. FOCiS

Tolerance 2. Regulatory T cells; why tolerance fails. Abul K. Abbas UCSF. FOCiS 1 Tolerance 2. Regulatory T cells; why tolerance fails Abul K. Abbas UCSF FOCiS 2 Lecture outline Regulatory T cells: functions and clinical relevance Pathogenesis of autoimmunity: why selftolerance fails

More information

ACTIVATION AND EFFECTOR FUNCTIONS OF CELL-MEDIATED IMMUNITY AND NK CELLS. Choompone Sakonwasun, MD (Hons), FRCPT

ACTIVATION AND EFFECTOR FUNCTIONS OF CELL-MEDIATED IMMUNITY AND NK CELLS. Choompone Sakonwasun, MD (Hons), FRCPT ACTIVATION AND EFFECTOR FUNCTIONS OF CELL-MEDIATED IMMUNITY AND NK CELLS Choompone Sakonwasun, MD (Hons), FRCPT Types of Adaptive Immunity Types of T Cell-mediated Immune Reactions CTLs = cytotoxic T lymphocytes

More information

The Digestive System. What is the advantage of a one-way gut? If you swallow something, is it really inside you?

The Digestive System. What is the advantage of a one-way gut? If you swallow something, is it really inside you? The Digestive System What is the advantage of a one-way gut?! If you swallow something, is it really inside you? Functions and Processes of the Digestive System: Move nutrients, water, electrolytes from

More information

Descendants of Luigi Lobosco

Descendants of Luigi Lobosco Descendants of Luigi Lobosco Generation No. 1 1. Luigi 3 Lobosco (Michele 2, Rosario 1 ) was born September 02, 1895 in Sala Consilina, Italy, and died February 25, 1978 in Paterson, New He married Antonia

More information

Visceral Pain and Irritable Bowel Syndrome

Visceral Pain and Irritable Bowel Syndrome Visceral Pain and Irritable Bowel Syndrome Victor Chaban, PhD, MS Professor Charles R. Drew University of Medicine and Science University of California Los Angeles Editor In Chief, International Journal

More information

Gastrointestinal Physiology

Gastrointestinal Physiology Gastrointestinal Physiology Digestion and Absorption Definition Digestion: i Food dis dissolved d and broken down. Physical digestion: Propulsion and mixing of food by muscle in the alimentary tract. Chemical

More information

Cell Signaling (part 1)

Cell Signaling (part 1) 15 Cell Signaling (part 1) Introduction Bacteria and unicellular eukaryotes respond to environmental signals and to signaling molecules secreted by other cells for mating and other communication. In multicellular

More information

Parenteral Nutrition. Outline. Potential Biomarkers for Use in Intestinal Adaptation. Jejunum is primary site of digestion and absorption

Parenteral Nutrition. Outline. Potential Biomarkers for Use in Intestinal Adaptation. Jejunum is primary site of digestion and absorption Outline Potential Biomarkers for Use in Intestinal Adaptation Kelly A. Tappenden, Ph.D., R.D. Professor of Nutrition and GI Physiology 1. Intestinal Adaptation potential regulators 2. Intestinal mucosal

More information

CB2-mediated immunoregulation in Inflammatory Bowel Disease. David Ziring, MD Clinical Instructor, UCLA Div of Peds GI

CB2-mediated immunoregulation in Inflammatory Bowel Disease. David Ziring, MD Clinical Instructor, UCLA Div of Peds GI CB2-mediated immunoregulation in Inflammatory Bowel Disease David Ziring, MD Clinical Instructor, UCLA Div of Peds GI Overview Why study cannabinoid signaling in intestinal immunoregulation? G_i2 -/- mice

More information

Understanding clinical aspects of Crohn s disease and ulcerative colitis: Implications for the basic scientist

Understanding clinical aspects of Crohn s disease and ulcerative colitis: Implications for the basic scientist Understanding clinical aspects of Crohn s disease and ulcerative colitis: Implications for the basic scientist Scott Plevy, MD Associate Professor of Medicine, Microbiology & Immunology UNC School of Medicine

More information

1. The scavenger receptor, CD36, functions as a coreceptor for which TLR? a. TLR ½ b. TLR 3 c. TLR 4 d. TLR 2/6

1. The scavenger receptor, CD36, functions as a coreceptor for which TLR? a. TLR ½ b. TLR 3 c. TLR 4 d. TLR 2/6 Allergy and Immunology Review Corner: Cellular and Molecular Immunology, 8th Edition By Abul K. Abbas, MBBS, Andrew H. H. Lichtman, MD, PhD and Shiv Pillai, MBBS, PhD. Chapter 4 (pages 62-74): Innate Immunity

More information

DIGESTIVE PHYSIOLOGY

DIGESTIVE PHYSIOLOGY DIGESTIVE PHYSIOLOGY GASTROINTESTINAL PHYSIOLOGY Ingested foodstuff contributes to an increase in the overall weight of the animal, but does not become an integral part of the structure or metabolic activities

More information

XV Jornada de Avances en Hepatología Málaga 20 y 21 de Mayo de Barrera intestinal en la cirrosis. Agustín Albillos

XV Jornada de Avances en Hepatología Málaga 20 y 21 de Mayo de Barrera intestinal en la cirrosis. Agustín Albillos XV Jornada de Avances en Hepatología Málaga 20 y 21 de Mayo de 2016 Barrera intestinal en la cirrosis Agustín Albillos Hospital Universitario Ramón y Cajal Universidad de Alcalá, Ciberehd Madrid, Spain

More information

Growth Hormone, Somatostatin, and Prolactin 1 & 2 Mohammed Y. Kalimi, Ph.D.

Growth Hormone, Somatostatin, and Prolactin 1 & 2 Mohammed Y. Kalimi, Ph.D. Growth Hormone, Somatostatin, and Prolactin 1 & 2 Mohammed Y. Kalimi, Ph.D. I. Growth Hormone (somatotropin): Growth hormone (GH) is a 191 amino acid single chain polypeptide (MW 22,000 daltons). Growth

More information

Understanding Root Cause: Pathogenesis of Hepatic Fibrosis

Understanding Root Cause: Pathogenesis of Hepatic Fibrosis 10/1/12 Understanding Root Cause: Pathogenesis of Hepatic Fibrosis Hepatitis C Virus Mild inflammation Inflammation Fibrosis Cirrhosis 1 10/1/12 Non-alcoholic Fatty Liver Disease Steatosis Steatohepatitis

More information

Curriculum Vitae. Yosef Jose Greenspon, M.D. Include faculty appointment with rank as well as administrative roles

Curriculum Vitae. Yosef Jose Greenspon, M.D. Include faculty appointment with rank as well as administrative roles 1 Revised 3/7/2013 Curriculum Vitae Yosef Jose Greenspon, M.D. Personal Information Professional Address Phone 314-577-5629 Fax 314-268-6454 Current Position, Institution and start date Include faculty

More information

Effector T Cells and

Effector T Cells and 1 Effector T Cells and Cytokines Andrew Lichtman, MD PhD Brigham and Women's Hospital Harvard Medical School 2 Lecture outline Cytokines Subsets of CD4+ T cells: definitions, functions, development New

More information

Prepared by Cyrus H. Nozad, MD, University of Tennessee and John Seyerle, MD, Ohio State University

Prepared by Cyrus H. Nozad, MD, University of Tennessee and John Seyerle, MD, Ohio State University Allergy and Immunology Review Corner: Chapter 21 of Middleton s Allergy Principles and Practice, Seventh Edition, edited by N. Franklin Adkinson, et al. Chapter 21: Antigen-Presenting Dendritic Cells (Pages

More information

New and Emerging Therapies in IBD. Sarah Streett MD, AGAF Clinical Associate Professor of Medicine Stanford University

New and Emerging Therapies in IBD. Sarah Streett MD, AGAF Clinical Associate Professor of Medicine Stanford University New and Emerging Therapies in IBD Sarah Streett MD, AGAF Clinical Associate Professor of Medicine Stanford University New and Emerging Therapies in IBD I have no relevant financial disclosures. IBD is

More information

Immunology MIMM-314 MID-TERM II EXAMINATION. 1 hour between 8:30 a.m. - 10:00 a.m. McIntyre Medical Rm 504 (Martin Amphitheatre)

Immunology MIMM-314 MID-TERM II EXAMINATION. 1 hour between 8:30 a.m. - 10:00 a.m. McIntyre Medical Rm 504 (Martin Amphitheatre) GROUP (Version) 1 Annotated version April 8, 2011, RGEP DEPARTMENT OF MICROBIOLOGY AND IMMUNOLOGY Immunology MIMM-314 MID-TERM II EXAMINATION Course Coordinator: Dr. Roger Palfree Date: Thursday, March

More information

Curriculum Vitae. Lawrence E Stern, MD, FACS, FASCRS

Curriculum Vitae. Lawrence E Stern, MD, FACS, FASCRS Curriculum Vitae Lawrence E Stern, MD, FACS, FASCRS Education: Doctor of Medicine: Bachelor of Science, Biology: University of Virginia Health Sciences Center Charlottesville, Virginia University of Michigan

More information

MILTON HELPERN AWARD AMERICAN ACADEMY OF FORENSIC SCIENCES PATHOLOGY/BIOLOGY SECTION

MILTON HELPERN AWARD AMERICAN ACADEMY OF FORENSIC SCIENCES PATHOLOGY/BIOLOGY SECTION MILTON HELPERN AWARD Lemoyne Snyder... February 1987 Charles P. Larson Russell S. Fisher... February 1988 John I. Coe George E. Gantner (posthumous)... February 1989 Ali Z. Hameli, MD... February 1990

More information

Mucosal Immunology Sophomore Dental and Optometry Microbiology Section I: Immunology. Robin Lorenz

Mucosal Immunology Sophomore Dental and Optometry Microbiology Section I: Immunology. Robin Lorenz Mucosal Immunology Sophomore Dental and Optometry Microbiology Section I: Immunology Robin Lorenz rlorenz@uab.edu Why do we Need to Understand How the Mucosal Immune System Works? The mucosa is the major

More information

Root & Branch Bulk Formula List

Root & Branch Bulk Formula List An asterisk * indicates the inclusion of 1 or more granule versions of an herb because of limited availability on the American herbal market. These products are usually animal in nature like E Jiao, Shui

More information

Medical Virology Immunology. Dr. Sameer Naji, MB, BCh, PhD (UK) Head of Basic Medical Sciences Dept. Faculty of Medicine The Hashemite University

Medical Virology Immunology. Dr. Sameer Naji, MB, BCh, PhD (UK) Head of Basic Medical Sciences Dept. Faculty of Medicine The Hashemite University Medical Virology Immunology Dr. Sameer Naji, MB, BCh, PhD (UK) Head of Basic Medical Sciences Dept. Faculty of Medicine The Hashemite University Human blood cells Phases of immune responses Microbe Naïve

More information

Butyrate induces cell apoptosis through activation of JNK MAP kinase pathway in human colon cancer RKO cells.

Butyrate induces cell apoptosis through activation of JNK MAP kinase pathway in human colon cancer RKO cells. Chem Biol Interact. 2010 May 14;185(3):174-81. Epub 2010 Mar 25. Butyrate induces cell apoptosis through activation of JNK MAP kinase pathway in human colon cancer RKO cells. Zhang Y, Zhou L, Bao YL, Wu

More information

DIVISION OF GASTROENTEROLOGY

DIVISION OF GASTROENTEROLOGY DR. Lloyd Mayer T H E H E N R Y D. J A N O W I T Z DIVISION OF GASTROENTEROLOGY Mount Sinai is consistently ranked among the top five gastroenterology centers in the nation. The irresistible combination

More information