University of Parma - Karolinska Institutet IV Workshop on Lipid Metabolism and Vascular Biology
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1 University of Parma - Karolinska Institutet IV Workshop on Lipid Metabolism and Vascular Biology Parma, Centro S. Elisabetta Campus Universitario 8-10 October, 2018 Organized by Franco Bernini (University of Parma, Italy) and Paolo Parini (Karolinska Institutet, Sweden) SCIENTIFIC and LOCAL COMMITTEE Ilaria Zanotti, Maria Pia Adorni, Nicoletta Ronda, Francesca Zimetti (University of Parma, Italy) Matteo Pedrelli (Karolinska Institutet, Sweden) SEZIONE REGIONALE EMILIA ROMAGNA 1
2 PROGRAMME Monday, October 8, :00-15:20 Arrival and registration 15:20-15:30 Welcome address 15:30 16:10 Turning trash to treasure: targeting endothelial non-coding RNAs in atherosclerosis Mark Feinberg (Harvard Medical School, USA) Symposium on atherosclerosis and vascular biology 16:10 16:30 Atherosclerosis is modulated by PLIN2 through a feed-forward loop between LXR and autophagy Shirin Pourteymour (Karolinska Institutet, Sweden) 16:30 16:50 Molecular mechanisms of carotid and femoral atherosclerosis Anton Razuvaev (Karolinska Institutet, Sweden) 16:50 17:10 Immunometabolic role of apolipoprotein E at the crossroads between systemic and immune cells cholesterol metabolism Fabrizia Bonacina (University of Milano, Italy) 17:10 17:30 Coffee break 17:30 17:50 Correlation of computed tomography with carotid plaque transcriptomes associates calcification to lesion-stabilization Eva Karlöf (Karolinska Institutet, Sweden) 17:50 18:10 Lipoprotein(a) levels and association to cardiovascular disease in patients with diabetes mellitus type 1 Karin Littman (Karolinska Institutet, Sweden) 18:10 18:30 Sphingosine 1-phosphate (S1P)/S1P receptor 1 (S1P1) axis as a modulator of macrophage functions Enrica Scalera (University of Parma, Italy) 18:30 18:50 Sphingosine 1-phosphate (S1P)/S1P1 axis and its role in insulin resistance Simone Battista (University of Parma, Italy) 2
3 18:50 19:10 Role of sphingosine 1-phosphate (S1P) and its receptor S1P3 in the reverse cholesterol transport Bianca Papotti (University of Parma, Italy) Free evening Tuesday, October 9, :15 9:55 Macrophage contribution to insulin resistance independently of inflammation Myriam Aouadi (Karolinska Institutet, Sweden) Symposium on lipid metabolism and related pathologies 9:55 10:15 ABCA1- and ABCG1-mediated cholesterol efflux capacity of cerebrospinal fluid is impaired in Alzheimer's disease Cinzia Marchi (University of Parma, Italy) 10:15 10:35 CRISPR-mediated correction of rare liver diseases Tomas Jakobsson (Karolinska Institutet, Sweden) 10:35 10:55 Lipoprotein and lipid metabolism in liver-humanized mice Mirko Minniti (Karolinska Institutet, Sweden) 10:55 11:15 Oxisterol metabolism in intestinal barrier functions Srustidhar Das (Karolinska Institutet, Sweden) 11:15 11:35 Roles of TGIF1 in lipid metabolism Camilla Pramfalk (Karolinska Institutet, Sweden) 11:35 11:55 Genetic hypoalphalipoproteinemia and inflammation: the role of monocytes Chiara Pavanello (University of Milano, Italy) 11:55 13:00 Light lunch 3
4 13:00 13:40 Fatty acids as master controllers of inflammation Philip Calder (University of Southampton, UK) Symposium on nutrition, lipid metabolism and inflammation 13:40 14:00 Dietary polyphenols and cardio-metabolic disease prevention: an overview Pedro Mena (University of Parma, Italy) 14:00 14:20 Insulin-like growth factor binding protein 7 (Igfbp7) secreted by liver macrophages directly regulates liver metabolism Cecilia Morgantini (Karolinska Institutet, Sweden) 14:20 14:40 Tryptophan metabolism in atherosclerosis - inflammation and lipid metabolism Martin Berg (Karolinska Institutet, Sweden) 14:40 15:00 Bile acid deficiency in gallstone disease Amit Laskar (Karolinska Institutet, Sweden) 15:00 15:20 Stearic acid induced lipotoxicity in circulating myeloid angiogenic cells: a network between inflammation, apoptosis and metabolism Valentina Spigoni (University of Parma, Italy) Free afternoon 19:30-23:00 Social Event (restaurant Gallo D Oro, Borgo della Salina 3, Parma) Wednesday, October 10, :15 9:55 Modulation of CNS lipids in the treatment of neurodegenerative diseases Monique Mulder (Erasmus University Medical Center, The Netherlands) 4
5 Symposium on pharmacological modulation of lipid metabolism and inflammation 9:55 10:15 Sphingosine 1-phosphate (S1P) in cardiovascular system: good, bad or both? Francesco Potí (University of Parma, Italy) 10:15 10:35 Sphingolipids and inflammation: what s new? Irene Zini (University of Parma, Italy) 10:35 10:55 Pharmacological modulation of sphingosine-1-phosphate receptors in mesenteric ischemia-reperfusion Valentina Vivo (University of Parma, Italy) 10:55 11:15 Ezetimibe in combination with simvastatin reduces remnant-cholesterol without affecting biliary lipid concentrations in gallstone patients Osman Ahmed (Karolinska Institutet, Sweden) 11:15 11:35 Hormonal effects on liver function Christina Savva (Karolinska Institutet, Sweden) 11:35 11:55 Long-term exposure to air pollution raises circulating levels of PCSK9 Chiara Macchi (University of Milano, Italy) 11:55 Closing Remarks Have a nice trip back home and hope to see you also next time in Stockholm!! Supported by: SEZIONE REGIONALE EMILIA ROMAGNA 5
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