Chem 109 C. Fall Armen Zakarian Office: Chemistry Bldn 2217

Save this PDF as:
 WORD  PNG  TXT  JPG

Size: px
Start display at page:

Download "Chem 109 C. Fall Armen Zakarian Office: Chemistry Bldn 2217"

Transcription

1 Chem 109 C Fall 2014 Armen Zakarian ffice: Chemistry Bldn 2217

2 Chapter 25 o Glycolysis : fates of pyruvate NADH, H + H + C 2 NADH, H + H - (S)-lactic acid lactate dehydrogenase; anaerobic conditions - pyruvate pyruvate decarboxylase, TPP anaerobic, yeast alcohol dehydrogenase H pyruvate dehydrogenase system; aerobic conditions 2

3 Chapter 25 o Glycolysis : fates of pyruvate NADH, H + H + C 2 NADH, H + H - (S)-lactic acid lactate dehydrogenase; anaerobic conditions - pyruvate pyruvate decarboxylase, TPP anaerobic, yeast alcohol dehydrogenase H pyruvate dehydrogenase system; aerobic conditions PRACTICE PRBLEM Provide a mechanism for the reduction of acetaldehyde to ethanol with NADH. 3

4 o Catabolism of proteins: amino acids Chapter 25 - NH + 3 phenylalanine hydroxylase H - NH + 3 tyrosine aminotransferase PLP H - MECHANISM? phenylalanine tyrosine p-hydroxyphenylpyruvate p-hydroxyphenylalanine dioxygenase - H homogentisate - C + fumarate 4

5 o Catabolism of proteins: amino acids Chapter 25 - NH + 3 phenylalanine hydroxylase H - NH + 3 tyrosine aminotransferase PLP H - MECHANISM? phenylalanine tyrosine p-hydroxyphenylpyruvate oxidation decarboxylation p-hydroxyphenylalanine dioxygenase H H H - H epinephrine (adrenaline) NH 2 CH 3 homogentisate - C + fumarate 5

6 Chapter 25 PRACTICE PRBLEM Heptadecanoic, or margaric acid is a saturated fatty acid found in the fat and milkfat of ruminants. Its complete metabolism gives 7 equivalents of and one equivalent of propionyl-coa. Metabolism of propionyl-coa includes two reactions giving succinyl-coa, which is a citric cycle intermediate. Identify the coenzyme required for each step. - C propionyl-coa methylmalonyl-coa succinyl-coa 6

7 Chapter 25 PRACTICE PRBLEM What carbon atoms of glucose end up in ethanol under anaerobic conditions in yeast? 7

8 H 2 NADH, H + 8 H - C (S)-malate 7 - C H 2 oxaloacetate 1 CoASH H citrate citric acid cycle 2 1. eliminate H 2 2. add H 2 H isocitrate 3 Chapter 25 NADH, H +, C 2 - C fumarate FADH 2 FAD 6 - C 5 4 α-ketoglutarate, CoASH succinate GTP, CoASH succinyl-coa GDP, HP 2-3 NADH, H +, C 2 8

9 H 2 NADH, H + 8 H - C (S)-malate 7 - C H 2 oxaloacetate 1 CoASH H citrate citric acid cycle 2 1. eliminate H 2 2. add H 2 H isocitrate 3 Chapter 25 NADH, H +, C 2 - C fumarate FADH 2 FAD 6 - C 5 4 α-ketoglutarate, CoASH succinate GTP, CoASH succinyl-coa GDP, HP 2-3 NADH, H +, C 2 9

10 H 2 NADH, H + 8 H - C (S)-malate 7 - C H 2 oxaloacetate 1 CoASH H citrate citric acid cycle 2 1. eliminate H 2 2. add H 2 H isocitrate 3 Chapter 25 NADH, H +, C 2 - C fumarate FADH 2 FAD 6 - C 5 4 α-ketoglutarate, CoASH succinate GTP, CoASH succinyl-coa GDP, HP 2-3 NADH, H +, C 2 10

11 H 2 NADH, H + 8 H - C (S)-malate 7 - C H 2 oxaloacetate 1 CoASH H citrate citric acid cycle 2 1. eliminate H 2 2. add H 2 H isocitrate 3 Chapter 25 NADH, H +, C 2 - C fumarate FADH 2 FAD 6 - C 5 4 α-ketoglutarate, CoASH succinate GTP, CoASH succinyl-coa GDP, HP 2-3 NADH, H +, C 2 11

12 H 2 NADH, H + 8 H - C (S)-malate 7 - C H 2 oxaloacetate 1 CoASH H citrate citric acid cycle 2 1. eliminate H 2 2. add H 2 H isocitrate 3 Chapter 25 NADH, H +, C 2 - C fumarate FADH 2 FAD 6 - C 5 4 α-ketoglutarate, CoASH succinate GTP, CoASH succinyl-coa GDP, HP 2-3 NADH, H +, C 2 12

13 H 2 NADH, H + 8 H - C (S)-malate 7 - C H 2 oxaloacetate 1 CoASH H citrate citric acid cycle 2 1. eliminate H 2 2. add H 2 H isocitrate 3 Chapter 25 NADH, H +, C 2 - C fumarate FADH 2 FAD 6 - C 5 4 α-ketoglutarate, CoASH succinate GTP, CoASH succinyl-coa GDP, HP 2-3 NADH, H +, C 2 13

14 H 2 NADH, H + 8 H - C (S)-malate 7 - C H 2 oxaloacetate 1 CoASH H citrate citric acid cycle 2 1. eliminate H 2 2. add H 2 H isocitrate 3 Chapter 25 NADH, H +, C 2 - C fumarate FADH 2 FAD 6 - C 5 4 α-ketoglutarate, CoASH succinate GTP, CoASH succinyl-coa GDP, HP 2-3 NADH, H +, C 2 14

15 H 2 NADH, H + 8 H - C (S)-malate 7 - C H 2 oxaloacetate 1 CoASH H citrate citric acid cycle 2 1. eliminate H 2 2. add H 2 H isocitrate 3 Chapter 25 NADH, H +, C 2 - C fumarate FADH 2 FAD 6 - C 5 4 α-ketoglutarate, CoASH succinate GTP, CoASH succinyl-coa GDP, HP 2-3 NADH, H +, C 2 15

16 H 2 NADH, H + 8 H - C (S)-malate 7 - C H 2 oxaloacetate 1 CoASH H citrate citric acid cycle 2 1. eliminate H 2 2. add H 2 H isocitrate 3 Chapter 25 NADH, H +, C 2 - C fumarate FADH 2 FAD 6 - C 5 4 α-ketoglutarate, CoASH succinate GTP, CoASH succinyl-coa GDP, HP 2-3 NADH, H +, C 2 16

17 Chapter 25 NADH 2.5 ATP FADH ATP 17

18 Chapter 25, brief summary Catabolism: fats 3 fatty acids + 1 glycerol glycerol DHA pyruvate [+1 ATP, +2 NADH] fatty acid fatty acyl-coa [-1 ATP] fatty acyl-coa [+1 FADH 2, +1 NADH] {β-oxidation} per 1 β-oxidation carbohydrates monosaccharides: glucose glycolysis - 10 reactions glucose 2 pyruvates [+ 2 ATP, + 2 NADH] proteins amino acids pyruvate, etc. 18

19 Chapter 25, brief summary pyruvate + C 2 pyruvate dehydrogenase system, [+1 NADH]! 2C 2 + CoASH [+ 1 ATP, + 3 NADH, + 1 FADH 2 ] 19

20 Chapter 25, brief summary stage 4 of catabolism: NADH 2.5 ATP FADH ATP 20

21 21.

22 Chapter 27, Lipids PRACTICE PRBLEM 26 When pyruvate is reduced by NADH to lactate, which hydrogen in lactate comes from NADH? 22

Chem 109 C. Fall Armen Zakarian Office: Chemistry Bldn 2217

Chem 109 C. Fall Armen Zakarian Office: Chemistry Bldn 2217 Chem 109 C Fall 2014 Armen Zakarian ffice: Chemistry Bldn 2217 o Catabolism of carbohydrates: 10 reactions of glycolysis Chapter 25 C C 2 C 2 D-glucose α-d-glucopyranose aworth projection α-d-glucopyranose

More information

MULTIPLE CHOICE QUESTIONS

MULTIPLE CHOICE QUESTIONS MULTIPLE CHOICE QUESTIONS 1. Which of the following statements concerning anabolic reactions is FALSE? A. They are generally endergonic. B. They usually require ATP. C. They are part of metabolism. D.

More information

Photosynthesis in chloroplasts. Cellular respiration in mitochondria ATP. ATP powers most cellular work

Photosynthesis in chloroplasts. Cellular respiration in mitochondria ATP. ATP powers most cellular work Light energy ECOSYSTEM CO + H O Photosynthesis in chloroplasts Cellular respiration in mitochondria Organic molecules + O powers most cellular work Heat energy 1 becomes oxidized (loses electron) becomes

More information

Citric Acid Cycle: Central Role in Catabolism. Entry of Pyruvate into the TCA cycle

Citric Acid Cycle: Central Role in Catabolism. Entry of Pyruvate into the TCA cycle Citric Acid Cycle: Central Role in Catabolism Stage II of catabolism involves the conversion of carbohydrates, fats and aminoacids into acetylcoa In aerobic organisms, citric acid cycle makes up the final

More information

TCA CYCLE (Citric Acid Cycle)

TCA CYCLE (Citric Acid Cycle) TCA CYCLE (Citric Acid Cycle) TCA CYCLE The Citric Acid Cycle is also known as: Kreb s cycle Sir Hans Krebs Nobel prize, 1953 TCA (tricarboxylic acid) cycle The citric acid cycle requires aerobic conditions!!!!

More information

Chapter 9. Cellular Respiration and Fermentation

Chapter 9. Cellular Respiration and Fermentation Chapter 9 Cellular Respiration and Fermentation Energy flows into an ecosystem as sunlight and leaves as heat Photosynthesis generates O 2 and organic molecules, which are used in cellular respiration

More information

4. Which step shows a split of one molecule into two smaller molecules? a. 2. d. 5

4. Which step shows a split of one molecule into two smaller molecules? a. 2. d. 5 1. Which of the following statements about NAD + is false? a. NAD + is reduced to NADH during both glycolysis and the citric acid cycle. b. NAD + has more chemical energy than NADH. c. NAD + is reduced

More information

Photosynthesis in chloroplasts CO2 + H2O. Cellular respiration in mitochondria ATP. powers most cellular work. Heat energy

Photosynthesis in chloroplasts CO2 + H2O. Cellular respiration in mitochondria ATP. powers most cellular work. Heat energy Figure 9-01 LE 9-2 Light energy ECOSYSTEM Photosynthesis in chloroplasts CO2 + H2O Cellular respiration in mitochondria Organic + O molecules 2 powers most cellular work Heat energy LE 9-UN161a becomes

More information

CH 7: Cell Respiration and Fermentation Overview. Concept 7.1: Catabolic pathways yield energy by oxidizing organic fuels

CH 7: Cell Respiration and Fermentation Overview. Concept 7.1: Catabolic pathways yield energy by oxidizing organic fuels CH 7: Cell Respiration and Fermentation Overview Living cells require energy from outside sources Some animals obtain energy by eating plants, and some animals feed on other organisms Energy flows into

More information

Cellular Respiration: Harvesting Chemical Energy

Cellular Respiration: Harvesting Chemical Energy Chapter 9 Cellular Respiration: Harvesting Chemical Energy You should be able to: 1. Explain how redox reactions are involved in energy exchanges. Name and describe the three stages of cellular respiration;

More information

Chapter 9 Overview. Aerobic Metabolism I: The Citric Acid Cycle. Live processes - series of oxidation-reduction reactions. Aerobic metabolism I

Chapter 9 Overview. Aerobic Metabolism I: The Citric Acid Cycle. Live processes - series of oxidation-reduction reactions. Aerobic metabolism I n n Chapter 9 Overview Aerobic Metabolism I: The Citric Acid Cycle Live processes - series of oxidation-reduction reactions Ingestion of proteins, carbohydrates, lipids Provide basic building blocks for

More information

Sheet #13. #Citric acid cycle made by zaid al-ghnaneem corrected by amer Al-salamat date 11/8/2016. Here we go.. Record #18

Sheet #13. #Citric acid cycle made by zaid al-ghnaneem corrected by amer Al-salamat date 11/8/2016. Here we go.. Record #18 1 Sheet #13 #Citric acid cycle made by zaid al-ghnaneem corrected by amer Al-salamat date 11/8/2016 Here we go.. Record #18 2 Three processes play central role in aerobic metabolism: 1) The citric acid

More information

The Citric Acid Cycle 19-1

The Citric Acid Cycle 19-1 The Citric Acid Cycle 19-1 The Citric Acid Cycle Three processes play central role in aerobic metabolism the citric acid cycle electron transport oxidative phosphorylation Metabolism consists of catabolism:

More information

Dr. Abir Alghanouchi Biochemistry department Sciences college

Dr. Abir Alghanouchi Biochemistry department Sciences college Dr. Abir Alghanouchi Biochemistry department Sciences college Under aerobic conditions, pyruvate(the product of glycolysis) passes by special pyruvatetransporter into mitochondria which proceeds as follows:

More information

BCH Graduate Survey of Biochemistry

BCH Graduate Survey of Biochemistry BCH 5045 Graduate Survey of Biochemistry Instructor: Charles Guy Producer: Ron Thomas Director: Glen Graham Lecture 50 Slide sets available at: http://hort.ifas.ufl.edu/teach/guyweb/bch5045/index.html

More information

Cellular Respiration: Harvesting Chemical Energy

Cellular Respiration: Harvesting Chemical Energy Chapter 9 Cellular Respiration: Harvesting Chemical Energy Edited by Shawn Lester PowerPoint Lecture Presentations for Biology Eighth Edition Neil Campbell and Jane Reece Lectures by Chris Romero, updated

More information

Cellular Metabolism. Biol 105 Lecture 6 Read Chapter 3 (pages 63 69)

Cellular Metabolism. Biol 105 Lecture 6 Read Chapter 3 (pages 63 69) Cellular Metabolism Biol 105 Lecture 6 Read Chapter 3 (pages 63 69) Metabolism Consists of all of the chemical reactions that take place in a cell Metabolism Animation Breaking Down Glucose For Energy

More information

Unit 2: Metabolic Processes

Unit 2: Metabolic Processes How is energy obtained biologically? Recall: Red Ox Reactions Unit 2: Metabolic Processes Oxidation Is the chief mechanism by which chemical potential energy is released This energy comes from reduced

More information

Citrate Cycle. Lecture 28. Key Concepts. The Citrate Cycle captures energy using redox reactions

Citrate Cycle. Lecture 28. Key Concepts. The Citrate Cycle captures energy using redox reactions Citrate Cycle Lecture 28 Key Concepts The Citrate Cycle captures energy using redox reactions Eight reactions of the Citrate Cycle Key control points in the Citrate Cycle regulate metabolic flux What role

More information

CHE 242 Exam 3 Practice Questions

CHE 242 Exam 3 Practice Questions CHE 242 Exam 3 Practice Questions Glucose metabolism 1. Below is depicted glucose catabolism. Indicate on the pathways the following: A) which reaction(s) of glycolysis are irreversible B) where energy

More information

Cellular Respiration: Harvesting Chemical Energy Chapter 9

Cellular Respiration: Harvesting Chemical Energy Chapter 9 Cellular Respiration: Harvesting Chemical Energy Chapter 9 Assemble polymers, pump substances across membranes, move and reproduce The giant panda Obtains energy for its cells by eating plants which get

More information

Aerobic Fate of Pyruvate. Chapter 16 Homework Assignment. Chapter 16 The Citric Acid Cycle

Aerobic Fate of Pyruvate. Chapter 16 Homework Assignment. Chapter 16 The Citric Acid Cycle Chapter 16 Homework Assignment The following problems will be due once we finish the chapter: 1, 3, 7, 10, 16, 19, 20 Additional Problem: Write out the eight reaction steps of the Citric Acid Cycle, using

More information

Cellular Respiration and Fermentation

Cellular Respiration and Fermentation LECTURE PRESENTATIONS For CAMPBELL BIOLOGY, NINTH EDITION Jane B. Reece, Lisa A. Urry, Michael L. Cain, Steven A. Wasserman, Peter V. Minorsky, Robert B. Jackson Chapter 9 Cellular Respiration and Fermentation

More information

Citrate Cycle Supplemental Reading

Citrate Cycle Supplemental Reading Citrate Cycle Supplemental Reading Key Concepts - The Citrate Cycle captures energy using redox reactions - Eight enzymatic reactions of the Citrate Cycle - Key control points in the citrate cycle regulate

More information

Cellular Respiration and Fermentation

Cellular Respiration and Fermentation Chapter 9 LECTURE PRESENTATIONS For CAMPBELL BIOLOGY, NINTH EDITION Jane B. Reece, Lisa A. Urry, Michael L. Cain, Steven A. Wasserman, Peter V. Minorsky, Robert B. Jackson Cellular Respiration and Fermentation

More information

Releasing Chemical Energy

Releasing Chemical Energy Releasing Chemical Energy Ø Energy From Carbohydrates Ø Aerobic Respiration/ Stages Ø Fermentation Ø Food as a Source of Energy How Do Cells Access the Chemical Energy in Carbohydrayes? Aerobic Respiration

More information

number Done by Corrected by Doctor Nafeth Abu Tarboush

number Done by Corrected by Doctor Nafeth Abu Tarboush number 7 Done by حسام أبو عوض Corrected by Shahd Alqudah Doctor Nafeth Abu Tarboush 1 P a g e As we have studied before, in the fourth reaction of the Krebs cycle, α- ketoglutarate is converted into Succinyl-CoA

More information

Cell Respiration Ch 7. Both autotrophs and heterotrophs use cellular respiration to make CO2 and water from

Cell Respiration Ch 7. Both autotrophs and heterotrophs use cellular respiration to make CO2 and water from Cell Respiration Ch 7 Objectives: Identify the 2 major steps of cellular respiration Describe the major events in glycolysis Compare lactic acid fermentation with alcoholic fermentation Calculate the efficiency

More information

III. Metabolism The Citric Acid Cycle

III. Metabolism The Citric Acid Cycle Department of Chemistry and Biochemistry University of Lethbridge III. Metabolism The Citric Acid Cycle Slide 1 The Eight Steps of the Citric Acid Cycle Enzymes: 4 dehydrogenases (2 decarboxylation) 3

More information

RESPIRATION: SYNTHESIS OF ATP. Clickers!

RESPIRATION: SYNTHESIS OF ATP. Clickers! RESPIRATION: SYNTHESIS OF ATP Clickers! Respiration is a series of coupled reactions Carbon (in glucose) is oxidized ATP is formed from ADP plus phosphate O 2 ADP + Pi CO 2 + H 2 O ATP Synthesis of ATP

More information

Nafith Abu Tarboush DDS, MSc, PhD

Nafith Abu Tarboush DDS, MSc, PhD Nafith Abu Tarboush DDS, MSc, PhD natarboush@ju.edu.jo www.facebook.com/natarboush Why do we need it? Location & where is it in the picture? Electron (energy) carrying molecules Components Enzymes & cofactors

More information

1 CH:14 RESPIRATION IN PLANTS https://biologyaipmt.com/

1 CH:14 RESPIRATION IN PLANTS https://biologyaipmt.com/ 1 CH:14 RESPIRATION IN PLANTS https://biologyaipmt.com/ CHAPTER 14 RESPIRATION IN PLANTS All the energy required for 'life' processes is obtained by oxidation of some macromolecules that we call 'food'.

More information

Cellular Respiration Part V: Oxidative Phosphorylation

Cellular Respiration Part V: Oxidative Phosphorylation Cellular Respiration Part V: Oxidative Phosphorylation Figure 9.16 Electron shuttles span membrane 2 NADH or 2 FADH 2 MITOCHONDRION 2 NADH 2 NADH 6 NADH 2 FADH 2 Glucose Glycolysis 2 Pyruvate Pyruvate

More information

Chapter 17 - Citric Acid Cycle

Chapter 17 - Citric Acid Cycle hapter 17 - itric Acid ycle I. Introduction - The citric acid cycle (A) was elucidated in the 1930's by ans Krebs, who first noticed that oxygen consumption in suspensions of pigeon breast muscle was greatly

More information

The Krebs cycle is a central pathway for recovering energy from three major metabolites: carbohydrates, fatty acids, and amino acids.

The Krebs cycle is a central pathway for recovering energy from three major metabolites: carbohydrates, fatty acids, and amino acids. Chapter 16 - Citric Acid Cycle TCA (tricarboxylic acid cycle) Citric acid cycle and Krebs cycle. Named after Sir Hans Krebs, Nobel Laureate. He worked as an assistant professor for Otto Warburg (Nobel

More information

Cellular Respiration: Harvesting Chemical Energy

Cellular Respiration: Harvesting Chemical Energy Chapter 9 Cellular Respiration: Harvesting Chemical Energy Overview: Life Is Work Living cells require energy from outside sources Some animals, such as the giant panda, obtain energy by eating plants,

More information

METABOLISM Sri Widia A Jusman Department of Biochemistry & Molecular Biology FMUI

METABOLISM Sri Widia A Jusman Department of Biochemistry & Molecular Biology FMUI METABOLISM Sri Widia A Jusman Department of Biochemistry & Molecular Biology FMUI 1 METABOLISM Process of how cells acquire, transform, store and use energy Study of the chemistry, regulation and energetics

More information

BY: RASAQ NURUDEEN OLAJIDE

BY: RASAQ NURUDEEN OLAJIDE BY: RASAQ NURUDEEN OLAJIDE LECTURE CONTENT INTRODUCTION CITRIC ACID CYCLE (T.C.A) PRODUCTION OF ACETYL CoA REACTIONS OF THE CITIRC ACID CYCLE THE AMPHIBOLIC NATURE OF THE T.C.A CYCLE THE GLYOXYLATE CYCLE

More information

How Cells Release Chemical Energy. Chapter 8

How Cells Release Chemical Energy. Chapter 8 How Cells Release Chemical Energy Chapter 8 Impacts, Issues: When Mitochondria Spin Their Wheels More than forty disorders related to defective mitochondria are known (such as Friedreich s ataxia); many

More information

Tricarboxylic Acid Cycle. TCA Cycle; Krebs Cycle; Citric Acid Cycle

Tricarboxylic Acid Cycle. TCA Cycle; Krebs Cycle; Citric Acid Cycle Tricarboxylic Acid ycle TA ycle; Krebs ycle; itric Acid ycle The Bridging Step: Pyruvate D hase O H 3 - - pyruvate O O - NAD + oash O 2 NADH O H 3 - - S - oa acetyl oa Pyruvate D hase omplex Multienzyme

More information

Chapter 8 Mitochondria and Cellular Respiration

Chapter 8 Mitochondria and Cellular Respiration Chapter 8 Mitochondria and Cellular Respiration Cellular respiration is the process of oxidizing food molecules, like glucose, to carbon dioxide and water. The energy released is trapped in the form of

More information

Chapter 9 Notes. Cellular Respiration and Fermentation

Chapter 9 Notes. Cellular Respiration and Fermentation Chapter 9 Notes Cellular Respiration and Fermentation Objectives Distinguish between fermentation and anaerobic respiration. Name the three stages of cellular respiration and state the region of the cell

More information

Photosynthesis and Cellular Respiration: Cellular Respiration

Photosynthesis and Cellular Respiration: Cellular Respiration Photosynthesis and Cellular Respiration: Cellular Respiration Unit Objective I can compare the processes of photosynthesis and cellular respiration in terms of energy flow, reactants, and products. During

More information

Tricarboxylic Acid Cycle

Tricarboxylic Acid Cycle Tricarboxylic Acid Cycle Overview (Also called KREBS CYCLE, or CITRIC ACID CYCLE ) Occur totally in mitochondria. TCA cycle is an aerobic pathway, bcz O 2 is required as the final electron accepter. Supplies

More information

How Cells Release Chemical Energy Cellular Respiration

How Cells Release Chemical Energy Cellular Respiration How Cells Release Chemical Energy Cellular Respiration Overview of Cellular Respiration HO double membrane outer membrane inner membrane CO matrix Produces molecules Requires oxygen Releases carbon dioxide

More information

MITOCHONDRIA LECTURES OVERVIEW

MITOCHONDRIA LECTURES OVERVIEW 1 MITOCHONDRIA LECTURES OVERVIEW A. MITOCHONDRIA LECTURES OVERVIEW Mitochondrial Structure The arrangement of membranes: distinct inner and outer membranes, The location of ATPase, DNA and ribosomes The

More information

ANSC 619 PHYSIOLOGICAL CHEMISTRY OF LIVESTOCK SPECIES. Carbohydrate Metabolism

ANSC 619 PHYSIOLOGICAL CHEMISTRY OF LIVESTOCK SPECIES. Carbohydrate Metabolism ANSC 619 PHYSIOLOGICAL CHEMISTRY OF LIVESTOCK SPECIES I. Glycolysis A. Pathway Regulation of glycolysis Hexokinase: Activated by glucose. Inhibited by G6P. 6-Phosphofructokinase: Inhibited by ATP, especially

More information

Cellular Respiration Harvesting Chemical Energy ATP

Cellular Respiration Harvesting Chemical Energy ATP Cellular Respiration Harvesting Chemical Energy ATP 2006-2007 What s the point? The point is to make ATP! ATP 2006-2007 Harvesting stored energy Energy is stored in organic molecules carbohydrates, fats,

More information

A) Choose the correct answer: 1) Reduction of a substance can mostly occur in the living cells by:

A) Choose the correct answer: 1) Reduction of a substance can mostly occur in the living cells by: Code: 1 1) Reduction of a substance can mostly occur in the living cells by: (a) Addition of oxygen (b) Removal of electrons (c) Addition of electrons (d) Addition of hydrogen 2) Starting with succinate

More information

Energy Production In A Cell (Chapter 25 Metabolism)

Energy Production In A Cell (Chapter 25 Metabolism) Energy Production In A Cell (Chapter 25 Metabolism) Large food molecules contain a lot of potential energy in the form of chemical bonds but it requires a lot of work to liberate the energy. Cells need

More information

What s the point? The point is to make ATP! ATP

What s the point? The point is to make ATP! ATP ATP Chapter 8 What s the point? The point is to make ATP! ATP Flows into an ecosystem as sunlight and leaves as heat Energy is stored in organic compounds Carbohydrates, lipids, proteins Heterotrophs eat

More information

Active Learning Exercise 5. Cellular Respiration

Active Learning Exercise 5. Cellular Respiration Name Biol 211 - Group Number Active Learning Exercise 5. Cellular Respiration Reference: Chapter 9 (Biology by Campbell/Reece, 8 th ed.) 1. Give the overall balanced chemical equation for aerobic cellular

More information

Cellular Respiration and Fermentation

Cellular Respiration and Fermentation LECTURE PRESENTATIONS For CAMPBELL BIOLOGY, NINTH EDITION Jane B. Reece, Lisa A. Urry, Michael L. Cain, Steven A. Wasserman, Peter V. Minorsky, Robert B. Jackson Chapter 9 Cellular Respiration and Fermentation

More information

NAME KEY ID # EXAM 3a BIOC 460. Wednesday April 10, Please include your name and ID# on each page. Limit your answers to the space provided!

NAME KEY ID # EXAM 3a BIOC 460. Wednesday April 10, Please include your name and ID# on each page. Limit your answers to the space provided! EXAM 3a BIOC 460 Wednesday April 10, 2002 Please include your name and ID# on each page. Limit your answers to the space provided! 1 1. (5 pts.) Define the term energy charge: Energy charge refers to the

More information

CHAPTER 7 10/16/2012. How cells release Chemical Energy

CHAPTER 7 10/16/2012. How cells release Chemical Energy CHAPTER 7 10/16/2012 How cells release Chemical Energy 1 7.1 OVERVIEW OF CARBOHYDRATE BREAKDOWN PATHWAYS Organisms stay alive by taking in energy. Plants and all other photosynthetic autotrophs get energy

More information

Cellular Respiration: Harvesting Chemical Energy

Cellular Respiration: Harvesting Chemical Energy Chapter 9 Cellular Respiration: Harvesting Chemical Energy PowerPoint Lecture Presentations for Biology Eighth Edition Neil Campbell and Jane Reece Lectures by Chris Romero, updated by Erin Barley with

More information

3.7.1 Define cell respiration [Cell respiration is the controlled release of energy from organic compounds in cells to form ATP]

3.7.1 Define cell respiration [Cell respiration is the controlled release of energy from organic compounds in cells to form ATP] 3.7 Cell respiration ( Chapter 9 in Campbell's book) 3.7.1 Define cell respiration [Cell respiration is the controlled release of energy from organic compounds in cells to form ATP] Organic compounds store

More information

LAB 6 Fermentation & Cellular Respiration

LAB 6 Fermentation & Cellular Respiration LAB 6 Fermentation & Cellular Respiration INTRODUCTION The cells of all living organisms require energy to keep themselves alive and fulfilling their roles. Where does this energy come from? The answer

More information

2/25/2015. Anaerobic Pathways. Glycolysis. Alternate Endpoints. Gluconeogenesis fate of end products

2/25/2015. Anaerobic Pathways. Glycolysis. Alternate Endpoints. Gluconeogenesis fate of end products Anaerobic Pathways Glycolysis Glucose + 2 ATP 4 ATP + 2 Pyruvate No oxygen required Fairly low energy yield Lactate byproduct Resting levels low Tolerances 40 mmole/kg in humans, 200 mmole/kg in sea turtles

More information

Concept 9.1: Catabolic pathways yield energy by oxidizing organic fuels Several processes are central to cellular respiration and related pathways

Concept 9.1: Catabolic pathways yield energy by oxidizing organic fuels Several processes are central to cellular respiration and related pathways Overview: Life Is Work Living cells require energy from outside sources Some animals, such as the chimpanzee, obtain energy by eating plants, and some animals feed on other organisms that eat plants Energy

More information

BPK 312 Nutrition for Fitness & Sport. Lecture 3

BPK 312 Nutrition for Fitness & Sport. Lecture 3 BPK 312 Nutrition for Fitness & Sport Lecture 3 Nutrient Roles in Bioenergetics 1. Learning Objectives for Lecture 3 2. Bioenergetics/Conservation of Energy 3. Redox Reactions 4. ATP/Phosphocreatine 5.

More information

Respiration 30/04/2013. Dr.M.R.Vaezi K., Hakim Sabzevari University

Respiration 30/04/2013. Dr.M.R.Vaezi K., Hakim Sabzevari University Respiration Metabolism - the sum of all the chemical reactions that occur in the body. It is comprised of: anabolism synthesis of molecules, requires input of energy catabolism break down of molecules,

More information

CHAPTER 5 MICROBIAL METABOLISM

CHAPTER 5 MICROBIAL METABOLISM CHAPTER 5 MICROBIAL METABOLISM I. Catabolic and Anabolic Reactions A. Metabolism - The sum of all chemical reactions within a living cell either releasing or requiring energy. (Overhead) Fig 5.1 1. Catabolism

More information

Chapter 9: Cellular Respiration: Harvesting Chemical Energy

Chapter 9: Cellular Respiration: Harvesting Chemical Energy AP Biology Reading Guide Name: Date: Period Chapter 9: Cellular Respiration: Harvesting Chemical Energy Overview: Before getting involved with the details of cellular respiration and photosynthesis, take

More information

Transport. Oxidation. Electron. which the en the ETC and. of NADH an. nd FADH 2 by ation. Both, Phosphorylation. Glycolysis Glucose.

Transport. Oxidation. Electron. which the en the ETC and. of NADH an. nd FADH 2 by ation. Both, Phosphorylation. Glycolysis Glucose. Electron Transport Chain and Oxidation Phosphorylation When one glucose molecule is oxidized to six CO 2 molecules by way of glycolysiss and TCA cycle, considerable amount of energy (ATP) is generated.

More information

Fatty Acid Degradation. Catabolism Overview. TAG and FA 11/11/2015. Chapter 27, Stryer Short Course. Lipids as a fuel source diet Beta oxidation

Fatty Acid Degradation. Catabolism Overview. TAG and FA 11/11/2015. Chapter 27, Stryer Short Course. Lipids as a fuel source diet Beta oxidation Fatty Acid Degradation Chapter 27, Stryer Short Course Catabolism verview Lipids as a fuel source diet Beta oxidation saturated Unsaturated dd chain Ketone bodies as fuel Physiology High energy More reduced

More information

Energy stores in different organs for a 155 lb male, in Calories

Energy stores in different organs for a 155 lb male, in Calories Energy stores in different organs for a 155 lb male, in Calories Organ Glucose/ Glycogen Triacyl Glycerols* Liver 400 450 400 Brain 8 0 0 Mobile Proteins Muscle 1,200 450 24,000 Adipose Tissue 80 135,000

More information

Cellular Respiration: Harvesting Chemical Energy

Cellular Respiration: Harvesting Chemical Energy Chapter 9 Cellular Respiration: Harvesting Chemical Energy PowerPoint Lecture Presentations for Biology Eighth Edition Neil Campbell and Jane Reece Lectures by Chris Romero, updated by Erin Barley with

More information

Cellular Respiration

Cellular Respiration Cellular Respiration The breakdown of glucose for cellular energy. happens in all living cells. is exothermic H atoms and e are removed from glucose (oxidization) and added to oxygen (reduction) excess

More information

FREE ENERGY Reactions involving free energy: 1. Exergonic 2. Endergonic

FREE ENERGY Reactions involving free energy: 1. Exergonic 2. Endergonic BIOENERGETICS FREE ENERGY It is the portion of the total energy change in a system that is available for doing work at constant temperature and pressure; it is represented as ΔG. Reactions involving free

More information

Metabolism: From Food to Life

Metabolism: From Food to Life CHAPTER 7 Metabolism: From Food to Life Chapter Summary Metabolism is the sum total of all chemical and physical processes by which the body catabolizes and anabolizes molecules. Metabolic pathways are

More information

24 METABOLISM AND NUTRITION

24 METABOLISM AND NUTRITION CHAPTER 24 METABOLISM AND NUTRITION 1079 24 METABOLISM AND NUTRITION Figure 24.1 Metabolism Metabolism is the sum of all energy-requiring and energy-consuming processes of the body. Many factors contribute

More information

page1 (of9) BIBC102 Midterm 1 Sp 2009

page1 (of9) BIBC102 Midterm 1 Sp 2009 page1 (of9) 1) (2 pts) Define catabolism and anabolism. One sentence each should be fine. Catabolism- group of metabolic pathways that break down molecules to gain energy and precursors for biosynthesis

More information

2: Describe glycolysis in general terms, including the molecules that exist at its start and end and some intermediates

2: Describe glycolysis in general terms, including the molecules that exist at its start and end and some intermediates 1 Life 20 - Glycolysis Raven & Johnson Chapter 9 (parts) Objectives 1: Know the location of glycolysis in a eukaryotic cell 2: Describe glycolysis in general terms, including the molecules that exist at

More information

Cellular Respiration Harvesting Chemical Energy ATP

Cellular Respiration Harvesting Chemical Energy ATP Cellular Respiration Harvesting Chemical Energy ATP 2006-2007 What s the point? The point is to make ATP! ATP 2006-2007 Harvesting stored energy Energy is stored in organic molecules carbohydrates, fats,

More information

Fate of Dietary Protein

Fate of Dietary Protein Fate of Dietary Protein Dietary protein Stomach: l, pepsin Denatured and partially hydrolyzed protein (large polypeptides) small intestine: proteases Amino acids and dipeptides intestinal lining: proteases

More information

I tried to put as many questions as possible, but unfortunately only answers were found without the questions.

I tried to put as many questions as possible, but unfortunately only answers were found without the questions. I tried to put as many questions as possible, but unfortunately only answers were found without the questions. These are some questions from doctor2015 med exam : 1. One of them isn t acute phase protein

More information

2. What are the products of cellular respiration? Include all forms of energy that are products.

2. What are the products of cellular respiration? Include all forms of energy that are products. Name Per Cellular Respiration An Overview Why Respire Anyhoo? Because bucko all cells need usable chemical energy to do work. The methods cells use to convert glucose into ATP vary depending on the availability

More information

Amino Acid Metabolism

Amino Acid Metabolism Amino Acid Metabolism Fate of Dietary Protein Dietary protein Stomach: l, pepsin Denatured and partially hydrolyzed protein (large polypeptides) small intestine: proteases Amino acids and dipeptides intestinal

More information

Complete breakdown of Glucose: + Light + 6 H 2 O = C 6 H 12 O 6 6 CO O 2. + Energy = 6 CO 2 C 6 H 12 O 6. What is Glucose Metabolism?

Complete breakdown of Glucose: + Light + 6 H 2 O = C 6 H 12 O 6 6 CO O 2. + Energy = 6 CO 2 C 6 H 12 O 6. What is Glucose Metabolism? Chapter 8: Harvesting Energy: Glycolysis and Cellular Respiration What is Metabolism? Answer: The breakdown of glucose to release energy from its chemical bonds Photosynthesis: 6 CO 2 Carbon Dioxide +

More information

Name: KEY. Chem 3511 Exam 4

Name: KEY. Chem 3511 Exam 4 Chem 3511 Exam 4 The exam starts on the next page. It has 12 questions, worth a total of 100 points. Please write legibly and don t assume that long answers are required if there is a lot of space left

More information

Enzymes and Metabolism

Enzymes and Metabolism PowerPoint Lecture Slides prepared by Vince Austin, University of Kentucky Enzymes and Metabolism Human Anatomy & Physiology, Sixth Edition Elaine N. Marieb 1 Protein Macromolecules composed of combinations

More information

Fatty Acid and Triacylglycerol Metabolism 1

Fatty Acid and Triacylglycerol Metabolism 1 Fatty Acid and Triacylglycerol Metabolism 1 Mobilization of stored fats and oxidation of fatty acids Lippincott s Chapter 16 What is the first lecture about What is triacylglycerol Fatty acids structure

More information

Energy Metabolism. Topics

Energy Metabolism. Topics Energy Metabolism Nur Hidayat Topics TOPIC 1: OXIDATION, REDUCTION, AND NADH TOPIC 2: GLYCOLYSIS TOPIC 3: KREBS (CITRIC ACID) CYCLE TOPIC 4: ELECTRON TRANSPORT CHAIN AND OXIDATIVE PHOSPHORYLATION TOPIC

More information

Lipid Metabolism. Catabolism Overview

Lipid Metabolism. Catabolism Overview Lipid Metabolism Pratt & Cornely, Chapter 17 Catabolism Overview Lipids as a fuel source from diet Beta oxidation Mechanism ATP production Ketone bodies as fuel 1 High energy More reduced Little water

More information

Secondary Energy Deficiencies in Organic Acidemias. Kimberly A Chapman MD PhD Children s National July 26, 2014

Secondary Energy Deficiencies in Organic Acidemias. Kimberly A Chapman MD PhD Children s National July 26, 2014 Secondary Energy Deficiencies in Organic Acidemias Kimberly A Chapman MD PhD Children s National July 26, 2014 2 Goals of this talk Describe the secondary energy deficiencies seen in organic acidemias

More information

Metabolism. Metabolic pathways. BIO 5099: Molecular Biology for Computer Scientists (et al) Lecture 11: Metabolic Pathways

Metabolism. Metabolic pathways. BIO 5099: Molecular Biology for Computer Scientists (et al) Lecture 11: Metabolic Pathways BIO 5099: Molecular Biology for Computer Scientists (et al) Lecture 11: Metabolic Pathways http://compbio.uchsc.edu/hunter/bio5099 Larry.Hunter@uchsc.edu Metabolism Metabolism is the chemical change of

More information

Chapter 7, Cellular Respiration from Biology by Boundless is available under a Creative Commons Attribution-ShareAlike 4.0 International license.

Chapter 7, Cellular Respiration from Biology by Boundless is available under a Creative Commons Attribution-ShareAlike 4.0 International license. Chapter 7, Cellular Respiration from Biology by Boundless is available under a Creative Commons Attribution-ShareAlike 4.0 International license. 2015, boundless.com. CHAPTER 7 CELLULAR RESPIRATION 201

More information

Oxidative Phosphorylation

Oxidative Phosphorylation Electron Transport Chain (overview) The NADH and FADH 2, formed during glycolysis, β- oxidation and the TCA cycle, give up their electrons to reduce molecular O 2 to H 2 O. Electron transfer occurs through

More information

Section 9 2 The Krebs Cycle and Electron Transport (pages )

Section 9 2 The Krebs Cycle and Electron Transport (pages ) Section 9 2 The Krebs Cycle and Electron Transport (pages 226 232) This section describes what happens during the second stage of cellular respiration, called the Krebs cycle. It also explains how high-energy

More information

Information transmission

Information transmission 1-3-3 Case studies in Systems Biology Goutham Vemuri goutham@chalmers.se Information transmission Fluxome Metabolome flux 1 flux flux 3 Proteome metabolite1 metabolite metabolite3 protein 1 protein protein

More information

ENERGY DEFICIENCY IN ORGANIC ACIDEMIAS. Kimberly A. Chapman, M.D., Ph.D. Children s National Medical Center

ENERGY DEFICIENCY IN ORGANIC ACIDEMIAS. Kimberly A. Chapman, M.D., Ph.D. Children s National Medical Center ENERGY DEFICIENCY IN ORGANIC ACIDEMIAS Kimberly A. Chapman, M.D., Ph.D. Children s National Medical Center 1 What is energy? Energy is the money that drives all biological processes Protein (amino acids),

More information

ANSC/NUTR 618 Lipids & Lipid Metabolism

ANSC/NUTR 618 Lipids & Lipid Metabolism I. Overall concepts A. Definitions ANC/NUTR 618 Lipids & Lipid Metabolism 1. De novo synthesis = synthesis from non-fatty acid precursors a. Carbohydrate precursors (glucose, lactate, and pyruvate) b.

More information

Electron transport chain,oxidative phosphorylation & mitochondrial transport systems. M.Kohutiar, B.Sopko

Electron transport chain,oxidative phosphorylation & mitochondrial transport systems. M.Kohutiar, B.Sopko Electron transport chain,oxidative phosphorylation & mitochondrial transport systems. M.Kohutiar, B.Sopko Content 1. Structure of mitochondria Mitochondrial transport systems 2. Electron transport 3. Parts

More information

Chem Lecture 8 Carbohydrate Metabolism Part I: Glycolysis

Chem Lecture 8 Carbohydrate Metabolism Part I: Glycolysis Chem 352 - Lecture 8 Carbohydrate Metabolism Part I: Glycolysis Introduction Carbohydrate metabolism involves a collection of pathways. Glycolysis Hexoses 3-Carbon molecules Gluconeogenesis 3-Carbon molecules

More information

Cellular Respiration

Cellular Respiration Cellular Respiration 1. To perform cell work, cells require energy. a. A cell does three main kinds of work: i. Mechanical work, such as the beating of cilia, contraction of muscle cells, and movement

More information

Enzymes what are they?

Enzymes what are they? Topic 11 (ch8) Microbial Metabolism Topics Metabolism Energy Pathways Biosynthesis 1 Catabolism Anabolism Enzymes Metabolism 2 Metabolic balancing act Catabolism Enzymes involved in breakdown of complex

More information

Page 2 of 51 WJEC/CBAC 2016 pdfcrowd.com

Page 2 of 51 WJEC/CBAC 2016 pdfcrowd.com 1. Page 2 of 51 WJEC/CBAC 2016 Page 3 of 51 WJEC/CBAC 2016 2. Page 4 of 51 WJEC/CBAC 2016 Page 5 of 51 WJEC/CBAC 2016 3. Page 6 of 51 WJEC/CBAC 2016 Page 7 of 51 WJEC/CBAC 2016 4. Page 8 of 51 WJEC/CBAC

More information

Case Study: Carbohydrate Metabolism. eating an early dinner the night before and skipping breakfast that morning, Sid goes to the

Case Study: Carbohydrate Metabolism. eating an early dinner the night before and skipping breakfast that morning, Sid goes to the Student Name Biochemistry 4320 Case Study Part I 4 November 2013 Case Study: Carbohydrate Metabolism Sid is a high school student who has decided to start exercising before school. After eating an early

More information