The Power and Promise of Digital Health

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1 The Power and Promise of Digital Health Laurel Pickering, MPH EVP, Enterprise Solutions Welldoc, Inc WellDoc, Inc. Intellectual Property. All rights reserved

2 Agenda Problem are we trying to solve Changing consumer and healthcare system Digital health and digital therapeutics Artificial intelligence Diabetes and BlueStar as an example

3 What problem are we trying to solve?

4 Problems Increasing health care costs Increase in prevalence of chronic conditions (New CDC numbers: 14% of Americans have diabetes) Hard to get employees to take care of themselves and engage in their health Tried multiple programs; many don t work and employees don t engage

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8 Your employees are changing and so is healthcare The New Consumer Care is moving to virtual and on-demand

9 9 Meet Lara Today s Healthcare Consumer

10 Music MUSIC SPOTIFY

11 Music COMMUTE UBER

12 Music EXERCISE PELOTON

13 Music DOCTOR TELEDOC

14 Characteristics of Lara s Tools

15 2018 WellDoc, Inc. Intellectual Property. All rights reserved Personalized

16 2018 WellDoc, Inc. Intellectual Property. All rights reserved On-Demand

17 2018 WellDoc, Inc. Intellectual Property. All rights reserved Virtual

18 2018 WellDoc, Inc. Intellectual Property. All rights reserved 24/7

19 How do your tools fit into Lara s expectations? 19

20 Digital Diabetes Health Space Space new apps each day 314 Wearables available worldwide 20% of large health systems have full-scale digital health programs Confusion 60% of apps are just general wellness Patient Churn

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23 Investor Trends: 2018 biggest year Digital health is key focus of investors time and money Healthcare at home/on-demand health tools Significant digital therapeutics fundraising: Pear Therapeutics ($46M) Click Therapeutics ($17M) Focus on companies making care continuous, accessible, convenient 31 FDA approvals in digital health Big tech pushes into healthcare Amazon acquires PillPack Apple Watch Series 4 Akili Interactive Labs ($68M) Virta Health ($45M) Propeller Health ($20M) Hinge Health ($26M)

24 SVB Analytics, Consumer Digital Health: How Market Shift is Leading to New Opportunities, 2016

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27 Software as Medicine: Digital Therapeutics Digital therapeutics are at the forefront of a new era in digital health. These clinically validated solutions may be used as standalone interventions or in association with other treatments to engage patients and improve the overall quality, cohesion, outcomes and value of healthcare delivery. Criteria: 1. Data analysis and feedback is evidence and theory based and tailored to the individuals clinical needs, goals, and lifestyle 2. Connects the patient with their own health care team (integrate into practice) 3. Has demonstrated safety and efficacy in randomized clinical trials 4. Ensures the safety and security of the patient-generated health data 5. Obtained regulatory clearance when used as medical device and are developed in accordance with appropriate QA/RA standards 6. Designed to be user friendly and engaging

28 Where Does AI Fit In?

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30 It s a new world, where artificial intelligence (AI) is moving beyond a back-end tool for the healthcare enterprise to the forefront of the consumer and clinician experience.

31 AI is the New UI: Healthcare Experience Above All, Accenture, 2017

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34 Spotlight on Diabetes 34 NOISE IN THE SYSTEM KEY PLAYERS

35 People with Type 2 Diabetes Need a 24/7 Personal Assistant * *Turning the tide on diabetes management: How leaders in health care are using multi-faceted approaches, Deloitte, 2016

36 and people need a digital assistant they can trust April 2015 April 2018 January 2018 The BlueStar app is one of only a few apps backed by data from clinical trials. Adults with diabetes can use sophisticated mobile technology, such as Welldoc to effectively manage their lifestyles and conditions, reducing the need for inperson encounters. Yet this miracle of modern science is not a new pill. It is a smartphone app called BlueStar.

37 Our Solution BlueStar Powered by WellDoc Digital Personal Assistant Data-driven user experience and artificial intelligence combined with evidencebased medicine Named Top App for type 2 diabetes treatment 1 st digital therapeutic for diabetes 30 peer reviewed publications/posters including clinical outcomes in randomized controlled studies and real-world. Experience with 30,000 people with diabetes FDA Registered as a Class 2 Medical Device, works online & offline. HIPAA compliant. SOC 2 Certified. ISO for International Business by IQVIA November 2017 Source: IQVIA 2017 Report The Growing Value of Digital Health

38 BlueStar Ecosystem

39 Tailored, Comprehensive Experience Symptoms (Surveys, Notes) Meds (Adherence, Insights) Labs (BG, BP, Weight) Tracks and analyzes the 6 critical dimensions impacting diabetes, incl hypertension & weight management Psycho-social (Distress, Disability, Economic Conditions) Activity (Sleep/Exercise) Unique, real-time feedback messages given within each dimension Diet (Carbs, Calories, Sodium, Water)

40 A Closer Look at BlueStar Connect Plan & Track Real-time Feedback Medication Reminders Weekly Insights Longitudinal Patterns Provider Smart Visit Report

41 Key BlueStar Stats Engagement 24 weekly in-app actions Clinical Results Reduction in A1C Time to Results Most A1C reductions seen in first 3 months Cost Savings Average Savings of $251-$274 per month Quinn CC, Shardell MD, Terrin ML, Barr EA, Ballew SH, Gruber-Baldini AL. Cluster-randomized trial of a mobile phone personalized behavioral intervention for blood glucose control. Diabetes Care Sep;34(9): Erratum in: Diabetes Care Nov;36(11):3850. Tang, P. Peeples, M. Duni, J. Peskin,S. Macleod, J. Kowitt, S. Fisher, E. ehealth-assisted Lay Health Coaching for Diabetes Self-Management Support. ADA, New Orleans, Poster

42 Outcomes Peer-Reviewed Journals Over 32 peer reviewed posters and presentations 2.0 Point A1C Improvement (mean) 3 month RCT 1.9 Point A1C Improvement (mean) 12 month RCT 58% Reduction in Hospitalizations & ER Visits

43 Comparison of A1C Reduction T2D Treatment Average A1C Reduction Insulin BlueStar Metformin 1.5 Sulfonylureas 1.5 SGLT-2s BlueStar is second only to insulin in terms of ability to reduce A1C No side effects Fully scalable GLP-1R Agonist DPP-4 Inhibitor.6 -.8

44 Financial Outcomes WellDoc Validates Potential of Its Digital Therapeutic, BlueStar, to Significantly Reduce Healthcare Costs. $254-$271 Average Savings per User per Month Cost savings based on: Reductions in hospitalizations Emergency room visits Supplies and medications Co-morbid conditions 3-5x Average ROI

45 How Does it Work? You purchase BlueStar for your employees/patients/members We provide you with a unique code We work with you to market the tool and target, if possible blast, posters, phone outreach, onsite enrollment, website, existing platform, clinician education, workflow Employees/members/patients download the app from app store They use your unique code to activate You provide eligibility file We provide you with regular reporting: how many are using BlueStar, how often, what features are they using, blood glucose values, medication adherence, preventive exams, etc.

46 Keeping BlueStar Users Engaged In-app and out-of-app engagement methods Real-Time Feedback Messages Weekly Challenges Longitudinal Feedback Messages Weekly Summaries Diabetes Curriculum In-App Engagement Out-of-App Engagement Dynamic s Mobile Notifications Targeted Re-Engagement s BlueStar Team/Care Team Phone Outreach

47 Helping people live their best life I can t live without BlueStar! 5.8 A1C reduction in about 7 months Lost weight (over 70 pounds) More active and living a healthy lifestyle Feels BlueStar helped her get her life back BlueStar helps her keep her diabetes in control Candy K. Barnes 62 year old - Manager March Diagnosed with T2D April Began BlueStar Starting A1C: 11.5 Ending A1C: A1C reduction in ~7 months Recent A1C of 5.7 was recorded early Nov. 2017

48 It is amazing what a digital personal assistant can do for population health.

49 Laurel Pickering, MPH EVP, Enterprise Solutions

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