Principles of Biomedical Sciences Semester 1 Review
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1 Unit 1 The Mystery Lesson 1.1: Investigating the Scene 1. Why is it important to be careful and methodical when investigating a crime scene? 2. What are the main parts in the experimental design process? a. Define: Independent variable b. Define: Dependent variable 3. Give three examples of methods used to investigate crime scenes. 4. What is PPE and why is it important in crime scene investigations? 5. What were the pills found at the crime scene of Anna Garcia? a. What kind of method would be used to determine the identity of a mystery substance such as the pills? b. What kind of scientist would conduct this part of the investigation? 6. What type of evidence collected from a crime scene might contain DNA? 7. What information about a crime scene can be obtained by analyzing a bloodstain pattern? 8. How can height of a blood drop be determined? 9. What shape will be produced when a blood drop hits a surface from a 90 degree angle? 1
2 When an answer has more than one word leave a space (box) in the puzzle between each word. 1.1 Vocab 2
3 Lesson 1.2: DNA Analysis 1. What does DNA stand for? 2. What is the basic structural unit (monomer) of DNA? 3. What are the three components of a nucleotide? Draw the basic structure of the nucleotide and label each of the components. 4. What are the four bases in DNA? 5. What are Chargaff s base pair rules? 6. Using the base pair rules determine the complimentary strand for the following sequence: AATGCAATGGCC 7. What is the shape of DNA? a. What are the names of the scientists that discovered this shape? 8. Why is DNA considered a polymer? 9. What type of chemical bond is found between the paired bases of the DNA double helix? 10. Genes contain the instructions to assemble what type of molecule? 11. What are restriction enzymes and how are they used in DNA analysis? 12. What is an RFLP? 13. What caused DNA to run across a gel in gel electrophoresis? a. What size pieces of DNA would you find travel the furthest down a gel? 3
4 1.2 & 1.3 Vocab 4
5 Unit 1.3 The Findings 10. What is an Autopsy? a. Who performs and autopsy? b. What situations always require and autopsy? 11. What is included in an autopsy report? 12. What is the difference between cause and manner of death? 13. What are three examples of manner of death? 14. What are two examples of cause of death? 15. What is the difference between a coroner and a medical examiner? Unit 2 Diabetes Lesson 2.1: What is Diabetes? 1. What is the role of insulin in our body? a. Why is insulin needed in terms of cellular use of glucose? 2. How does insulin stimulate glucose to enter a cell within the body? 3. What is the protein channel called that allows glucose into the cell? 4. What is the difference between hyperglycemia and hypoglycemia? 5. How do Type 1 and Type 2 diabetes differ? 5
6 2.1 Vocab Name Date Period Lesson 2.2: The Science of Food 6. What is the role of a chemical bond in energy transfers? a. What does breaking these bonds provide for the body? b. How do we test for the heat energy contained in foods? c. What unit is food energy measured in? 7. What is the relationship between foods, nutrients, chemical reactions and energy? 6
7 a. Why do we eat food? b. What is our main source of energy? c. What food is a source of long term energy? 8. What are the main functions of a. Carbohydrates b. Proteins c. Lipids 9. What do the four macromolecules look like structurally? Identify the following molecules as carbohydrate, lipid, protein or nucleic acid. There WILL be pictures on the test. 10. Go back to the pictures in number 5: identify the monomer for each macromolecule. List it by the picture. 7
8 11. What types of foods supply a. Carbohydrates (sugars and starches) b. Proteins c. Lipids 12. Give two examples of foods that would provide more than one macromolecule. 13. How can macromolecules be detected in foods? 14. What are the basic recommendations for a diabetic diet? 15. What chemical reaction takes place to combine monomers to form a polymer? 16. What chemical reaction takes place to break apart a polymer? 17. What is the by-product of dehydration synthesis? 18. How is the amount of energy in food determined? a. What unit is used to measure food energy? 8
9 2.2 Vocab 9
10 Lesson 2.3: Life with Diabetes 19. What are the signs and symptoms for Type 1 and Type 2 Diabetes? 20. What are three possible complications resulting from diabetes? 21. What are the treatments for Type 1 and Type 2 Diabetes? 22. What is the normal level of glucose in the blood? 23. Why is it important for a diabetic to regularly check blood sugar levels? 10
11 2.3 Vocab 11
12 Unit 3 Sickle Cell Lesson 3.1: The Disease 1. What is sickle cell disease? 2. Describe what a sickle cell looks like. 3. What are the four parts of blood? List each and describe its function. 12
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