No White Coat No stethoscope: UNDER PRESSURE

Transcription

1 No White Coat No stethoscope: UNDER PRESSURE My people are destroyed for lack of knowledge: because thou hast rejected knowledge, I will also reject thee, that thou shalt be no priest to me seeing thou hast forgotten the law of thy God, I will also forget thy children. Hosea 4: 6 We have come to a time when every member of the church should take hold of medical missionary work. The world is a lazar house filled with victims of both physical and spiritual disease. Everywhere people are perishing for lack of a knowledge of truths that have been committed to us. The members of the church are in need of an awakening, that they may realize their responsibility to impart these truths. A Call to Medical Evangelism 10.5 Without a Knowledge of Health principles, no one is fitted for life s responsibilities. Ministry of Healing: Health Principles The study to which to give thought is that which concerns natural life, a knowledge of oneself... It is the house in which we live that we need to preserve, that we may do honor to God who has redeemed us. We need to know how to preserve the living machinery, that our soul, body, and spirit may be consecrated to his service. As rational beings we are deplorably ignorant of the body and its requirements. Healthful Living p. 13.5

2 So it is on this basis we will be going over the controlling apparatus that helps to regulate our blood pressure. But first Let us look at what is blood pressure. In layman s term Blood pressure is the Heart s ability to contract and relax. The contracting force that causes the blood to exert against the walls of your blood vessels is called SYSTOLIC and the relaxing pressure is called DIASTOLIC. Now if the Diastolic Number is high it means that certain hormones or enzymes secreted in the body is slowing up the RELAXATION TIME of the heart and smooth muscle of the blood vessels be it the arteries or capillaries. And if the Systolic Number is too high it means hormones or enzymes secreted in the body is prolonging the CONSTRICTION TIME of the heart and smooth muscle as well as causing the body to retain water and sodium. The Diastolic Pressure is controlled by the Parasympathetic nervous system and the Systolic Pressure is controlled by the Sympathetic nervous system.

3 HOPEFULLY THIS WILL GIVE YOU AN IDEA AS TO THE GENESIS OF CHRONIC HIGH BLOOD PRESURE. The Parasympathetic nervous system and the Sympathetic nervous system are the two divisions of the Autonomic nervous system, which is responsible for regulating the body's involuntary actions.

4 RENIN ANGIOTENSIN ALDOSTERONE SYSTEM (RAAS) is an involuntary bodily function carried out by the endocrine system and it plays a big role in the regulation of long term BP and extra cellular volume (Fluid Balance) in the body. Here is the 1st step in long term BP regulation As you can see here; the liver releases agiotensinogen (rennin substrate) into the blood circulation. NORMALLY whenever this happens it is usually in response to two things: low blood pressure and adverse changes in sodium concentration.

5 Here is the 2nd step in long term BP regulation An enzyme secreted by the Kidney called Renin function like a sharp Scissors and cut angiotensinogen into to two to form the inactive decapeptide angiotensin-1.

6 Angiotensin-1 is then transformed into angiotensin-2 by angiotensin converting enzyme (ACE) as you can see below in the illustrations. ACE converts the inactive decapeptide angiotensin-1 into the vasoactive peptide angiotensin-2, which can affect the diameter of blood vessels, which in turn affect blood pressure.

7 ACE is chiefly found in the Lungs; but is also produce in the thin layer of flattened cells that lines the inside of body cavities like the kidneys, adrenal glands, brain, and heart. David once song I am fearfully and wonderfully made and I can testify to that simply because I have been blessed to understand some things about the human body. Take for example; there are other pathways that do not use Renin and ACE to act upon the substrate angiotensinogen and angiotensin-1.

8 These alternative pathways are referred to as Non-Renin and Non-ACE pathway. In Non-Renin pathway the body uses two other enzymes, Tonin and Cathepsin D in the place of renin to release angiotensin-1 from angiotensinogen and tissue plasminogen activator (tpa) and can make angiotensin-2 directly from angiotensinogen without the use of Renin. Moreover, enzyme like Chymase can also form angiotensin-2 directly from angiotensin-1 independently of the ACE. I show you this so that you can see that God designed the body to rectify any and every ailment in more ways than one.

9 This illustration shows that both Angiotensin-2 and ACE inhibits the production of Nitric Oxide. Nitric Oxide function as vasodialator and ACE inhibit its production by degrading Bradykinin, which is required for the synthesis of this major blood vessel dilator; and angiotensin-2 binds to AT1-R that is expressed on the surface of vascular endothelium (flattened cells that line the surface of blood vessels and other body cavity) and impairs the synthesis of Nitric Oxide as well. Thus, reduce bioavailability of nitric oxide combined with the stimulation of AT1-R on smooth muscle cells leads to vasoconstriction.

10 In addition to a vasoconstriction effect, stimulation of AT1-R causes the adrenal glands to secrete the hormone Aldosterone, resulting in sodium and water retention. Sodium retention combined with vasoconstriction undoubtedly leads to increased blood pressure. At this juncture in my presentation I would like all of you to get your Bibles and read with me a few well known Bible passages. 2 Kings 2: 20 Matthew 5: 13 I use some salt, and always have, because from the light given me by God, this article, in the place of being deleterious, is actually essential for the blood. The whys and wherefores of this I know not, but I give you the instruction as it is given me. - Letter 37, 1901 CD Mrs. White was not told why it was important to consume salt; but although she was not told the reason, she understood there was a reason and so she obeyed.

11 My Line of reasoning is to help you understand that there is no such thing as an idiopathic disorder. Every symptom and disease has an underlying cause. LET US LOOK AT HOW WE CAN ELIMINATE HYPERTENTION BY INDENTIFING SOME OF THE CAUSES THAT GAVE RISE TO IT. You have a determined will, which causes the mind to react upon the body, unbalancing the circulation, and producing congestion in certain organs; and you are sacrificing health to your feelings. - Testimonies for the Church 5: HL (Excess Cortisol) The exercise of the brain in study without corresponding physical exercise has a tendency to attract the blood to the brain, and the circulation of the blood through the system becomes unbalanced. The brain has too much blood and the extremities too little. - Testimonies for the Church 3: HL (Lack of Exercise)

12 The chief if not the only reason why many become invalids is that the blood does not circulate freely, and the changes in the vital fluid which are necessary to life and health do not take place. They have not given their bodies exercise or their lungs food, which is pure, fresh air; therefore it is impossible for the blood to be vitalized, and it pursues its course sluggishly through the system. - Testimonies for the Church 2: HL (Reduced bioavailability Nitric Oxide) Your health is greatly injured by overeating and eating at improper times. This causes a determination of the blood to the brain... You are in danger of apoplexy; and if you continue to disobey the laws of health, your life will be cut short suddenly. - Testimonies for the Church 4:501, HL (Insulin Resistance) Flesh meats will depreciate the blood. Cook meat with spices, and eat it with rich cakes and pies, and you have a bad quality of blood. The system is too heavily taxed in disposing of this kind of food. - Testimonies for the Church 2: HL (Metabolic Syndrome) Question: what is Metabolic Syndrome? Answer: Metabolic syndrome is a cluster of conditions High blood pressure, high blood sugar, excess body fat around the waist, High cholesterol or triglyceride levels that occur together, increasing your risk of heart disease, stroke, diabetes, dementia, cancer, polycystic ovarian syndrome and non-alcoholic fatty liver.

13 Question: what is the common denominator of Metabolic Syndrome? Answer: Insulin Resistance or High insulin levels at improper times. Research links on insulin resistance: Hypertension link: Cancer link: Dementia link: rt00003 What is insulin resistance? Insulin resistance is a condition in which multiple tissues in the human body become resistant to the effects of insulin. Simply stated, insulin resistance occurs when tissues become dumb to insulin.

14 Question: what is the cause of insulin resistance? Answer: Insulin Resistance is caused by snacking, especially on fake carbohydrates (foods that are easily converted to glucose and stored as fat) or eating between meals and lack of exercise, which in turn lead to lipid overload in the body. When insulin is release and its main function The rise in blood glucose causes insulin to be released from the pancreas. Proteins in food and other hormones produced by the gut in response to food also stimulate insulin release. However, once the blood glucose levels return to normal, insulin release slows down. Insulin mainly controls how the body uses carbohydrate and fat found in food. Insulin allows cells in the muscles, liver and fat (adipose tissue) to take up sugar (glucose) that has been absorbed into the bloodstream from food. This provides energy to the cells. This glucose can also be converted into fat to provide energy when glucose levels are too low. In addition, insulin has several other metabolic effects (such as stopping the breakdown of protein and fat).

15 The whole insulin and glucose system looks like this: Elevated free fatty acid levels (due to snacking, lack of exercise and/or high dietary fat intake) cause insulin resistance in skeletal muscle and liver in the following way:

16 Insulin resistance, forces the pancreas to secrete increasing amounts of insulin into the blood, which in turn lead to a condition known as hyperinsulinemia. Hyperinsulinemia cause the body not to break down fats. Thus producing lipid overload, mitochondria dysfunction and low-grade inflammation; these contributes to the development of atherosclerotic vascular diseases and increased fat synthesis in the liver known as non-alcoholic fatty liver disease (NAFLD). This is the very reason God warned us not to eat fat (animal fat) Leviticus 3: 17