PRODUCT LIST. Ensuring the best natural solutions

Transcription

1 PRODUCT LIST Ensuring the best natural solutions

2 From Selected Botanical Ingredients to Innovative Natural Solutions Linnea experience in Natural Extracts is now extended to provide New Natural Solutions for targeted therapeutic applications. We improve the quality of life by manufacturing and supplying great natural solutions worldwide. Doing business responsibly. LINNEA INGREDIENTS Active Pharmaceutical Ingredients Purified Ingredients Herbal Extracts NioSkin TM - Niosome Active Ingredients NEW NeoSol TM - Water Soluble Ingredients NEW FINISHED PRODUCT PLATFORM A tailored and innovative solutions for finished products targeted to a wide range of medical applications. SylTech TM - Micro Silver System NEW FINISHED PRODUCT FINISHED PRODUCT APPLICATIONS Pharmaceutical Ingredients Dietary Supplements Cosmetics NEW Medical Devices NEW

3 LINNEA INGREDIENTS Your guarantee of the best Botanical Active Ingredients is our long experience in the manufacturing of Herbal Extracts, Purified Ingredients and Semi-synthetic APIs of Natural Origin. Linnea ingredients are manufactured in our Swiss GMP facility in compliance with international standards. ACTIVE PHARMACEUTICAL INGREDIENTS BUTYLSCOPOLAMINE (Hyoscine Butylbromide) Semisynthetic derivative of Duboisia leaves. USES: Antispasmodic (treatment of abdominal pain and cramps). HYJECT (Hyoscine Butylbromide) Semisynthetic derivative of Duboisia leaves. API non sterile, suitable for injectable use. USES: Antispasmodic (treatment of abdominal pain and cramps). VINPOCETINE Semisynthetic derivative of Voacanga africana seeds. USES: Peripheral vasodilator (brain support, cerebrovascular disorders and neuroprotection). VINJECT (Vinpocetine) Semisynthetic derivative of Voacanga africana seeds. API non sterile, suitable for injectable use. USES: Peripheral vasodilator (brain support, cerebrovascular disorders and neuroprotection). VINCAMINE Semisynthetic derivative of Voacanga africana seeds. USES: Peripheral vasodilator (brain support, cerebrovascular disorders and neuroprotection). HERBAL EXTRACTS BILBERRY Standardized and refined dry extract of Vaccinium myrtillus fruits (EP: between 32.4 % and 39.6 % anthocyanins; USP: NLT 36 % anthocyanins). TRADITIONAL USES: Eye health, vasoprotection and antioxidant. CANNABIS EXTRACT NEW Extract of Cannabis sativa L., 1-20% Cannabidiol (THC< 1%) TRADITIONAL USES: Antiepileptic, anti-inflammatory, anti-emetic, muscle relaxing, anxiolytic, neuroprotective and anti-psychotic activity. GINKGO BILOBA EPG 246 Refined and quantified dry extract of Ginkgo biloba leaves (between 22.0% and 27.0 % ginkgo flavon glycosides and NLT 6.0% terpene lactones). TRADITIONAL USES: Antioxidant and peripheral vasodilator (brain support, cerebrovascular disorders, neuroprotection and tinnitus). GINKGO BILOBA ETHANOL 246 E Herbal extract of Ginkgo biloba leaves (NLT 24% ginkgo flavon glycosides and NLT 6.0% terpene lactones). TRADITIONAL USES: Antioxidant and peripheral vasodilator (brain support, cerebrovascular disorders, neuroprotection and tinnitus). RED CLOVER IFL 40 Standardized and refined dry extract of Trifolium pratense aerial parts (between 36.0% and 44.0% total isoflavones). TRADITIONAL USES: Relief of menopausal symptoms. SAW PALMETTO FRUIT LIPIDIC EXTRACT Extract of Serenoa repens fruits (NLT 80.0 % total fatty acids, NLT 23 % lauric acid, NLT 0.20 % total sterols and NLT 0.10 % β sitosterol). TRADITIONAL USES: Prostate health (BHP). VALERIAN DRY HYDROALCOHOLIC EXTRACT Extract of Valeriana officinalis root (NLT 0.25 % sesquiterpenic acids). TRADITIONAL USES: Relief of mild nervous tension, mental stress and sleep disorders.

4 HAMAMELIS VIRGINIANA DISTILLATE Distillate of Hamamelis virginiana (Whitch hazel) twings (1:1.6 m/v). TRADITIONAL USES: Skin emollient, mild skin injuries or lesions, local inflammations, anti-hemorrhoids. ZEA MAYS UNSAPONIFIABLE FRACTION Extract of the unsaponifiable fraction of Zea mays oils (between 20.0 % and 25.0 % β sitosterol). TRADITIONAL USES: Dental and mouth disorders (gum disease). PURIFIED INGREDIENTS 5 HTP (L-5- Hydroxytryptophan) Purified extract of Griffonia simplicifolia seeds (NLT 99.0% L-5- Hydroxytryptophan). USES: Mood booster, antidepressant, migraine, appetite control and sleep disorders. HMRlignan TM (7-Hydroxymatairesinol) Purified extract of Picea abies knots (NLT 90% 7-Hydroxymatairesinol). USES: Cardiovascular protection. Metabolic syndrome. INGREDIENTS APPLICATIONS Therapeutic area Product Applications Mental Health L-5-HTP Mood improvement Headache Vincamine Vinpocetine Ginkgo biloba Cerebrovascular disorders Cognitive functions Tinnitus and vertigo Mood, Sleep and Anxiety Valerian Anxiety and sleep disorders L-5-HTP Mood & Sleep improvement Appetite control Stress management Garstrointestinal Disease Butylscopolamine Abdominal cramps Irritable Bowel Syndrome Dysmenorrhea Eye Health Bilberry Prevention of main ophthalmic disorders Vascular Health Bilberry Peripheral vascular disorders Ginkgo biloba Women s Health Red Clover Menopause symptoms HMRlignan Cardiovascular protection L-5-HTP Mood & Sleep improvement Appetite control Men s Health Red Clover Andropause HMRlignan Cardiovascular Health Saw Palmetto BPH (Benign Prostatic Hyperplasia) Antioxidant Bilberry Ophtalmology Vascular protection Ginkgo Vascular protection Neuroprotection General Discomforts Cannabis Anti-Emetic Anti-Inflammatory Anti epileptic Muscle relaxing Anxiolitic

5 LINNEA INNOVATIVE SOLUTIONS Innovative Patented Technology exclusively from Linnea WATER SOLUBLE INGREDIENTS NEW NeoSol is a proprietary new technology optimizing the solubility of Natural Extracts for dietary supplement applications. The new complex increases the availability of the active compounds, improving their physiological activity. This new technology allows the encapsulation in special carriers to obtain innovative and effective products for a wide range of solid and liquid formulations. As result of a balanced combination of nature and science we transform highly purified ingredients and standardized extracts in technological products. Through the selection of natural active compounds and their encapsulation in special carriers we design and develop effective ingredients suitable for targeted formulations. NIOSOME ACTIVE INGREDIENTS NEW NioSkin is an innovative solution making Linnea Extracts available for formulation of high quality cosmetic products. NioSkin Active Extracts is an innovative solution with improved skin absorption and proven effectiveness. The encapsulation into the niosome guarantees the effectiveness of the ingredients with optimal bioavailability and superior performances. Product Indication Product Indication NeoSol RCL40 Anti-aging Menopause Red Clover Isoflavone Aglycones Extract Antioxidant NeoSol Ginkgo Anti-aging Anti-cellulite Ginkgo Biloba 24/6 Extract Microcirculation Vascular protection Ocular microcirculation Tinnitus and vertigo NioSkin RCL40 Anti-aging Skin whitening Red Clover Isoflavone Aglycones Extract Antioxidant Skin tone lightening NioSkin HMRLignan Anti-aging Skin protection Picea Abies Purified Lignan Soothing for sensitive skin DNA damage protection 7-Hydroxymataresinol Extract Antioxidant NioSkin Ginkgo Anti-aging Microcirculation enhancer Ginkgo Biloba 24/6 Extract Anti-cellulite NioSkin Bilberry Anti-aging Microcirculation enhancer European Bilberry Anthocianins Extract Heavy legs Eye swelling Couperose Dark eye circles

6 FINISHED PRODUCTS Innovative and Customized Formulations available in License exclusively from Linnea. SylTech TM is a unique medical silver ready to market in a wide range of formulations. SylTech TM Medical Devices are licensed exclusively from Linnea with full marketing and scientific support. Capsules MICRO SILVER SYSTEM NEW SylTech TM is a patented system based on microparticles able to provide effective solutions in infective diseases and in mucosal healing. SylTech TM technology stabilizes silver monovalent ion with superior efficacy. SylTech TM protective film sinergistically provides antimicrobial, protective, and selfrepairing effects. SylTech TM medical device is suitable for application in Gynecology, Dermatology, Proctology, Ophthalmology and Oral Care. Cream Foam / Spray Soft gel Wipes APPLICATIONS Gynecology Vulvar Spray Foam Vulvar Gel Wipes with Hamamelis Under development Vaginal Capsules/Softgels Vaginal Gel with NioSkin RCL40 Under development Dermatology Topical Face Acne Cream Herpes Labial Cream Topical Repair Spray Powder Proctology Proctology Gel + Hamamelis Under development Wipes + Hamamelis Under development Ophthalmology Eye Gel Under development Mini Wipes + Hamamelis Under development Oral care High Density Aphte Gel Under development Oral Gel Under development Mouthwash Under development Vulvar vaginitis Vulvar surgery Vaginitis and Vaginosis Vaginal Dryness Day hospital surgery Acne Dermatitis Herpes (labial) Wounds healing Hemorrhoids Proctology post- surgery Prevention of cutaneous integrality Ocular infections Ocular dermatosis Post-surgery lesions Oral infections: Aphte, Gingivitis Oral mucositis Stomatitis Post-surgery lesions, implantology Skin Impurity Eczema

7 Global Presence Linnea s headquarters are based in Riazzino, a small town close to Maggiore Lake, in Ticino Canton, Switzerland. Linnea Inc., the American branch, was inaugurated in 1997, in Easton PA and manages the North American market. Headquarters Linnea SA Via Cantonale CH-6595 Riazzino (TI) Switzerland Tel: +41 (0) Fax: +41 (0) info@linnea.ch US office Linnea Inc. 435 McCartney Street Easton, PA USA Tel: (US) or Fax: dstanek@linnea.ch