Lecture 8. Section B (Week 2): Environmental and Chemical Triggers of Immune System Function and Dysfunction

Transcription

1 Lecture 8 Section B (Week 2): Environmental and Chemical Triggers of Immune System Function and Dysfunction 6. How does the environment affect our immune system function? 7. Effects of Diet on the immune system? 8. What can we do to boost the function of our immune system clinically proven and homeopathic approaches? 9. Plagues, epidemics, pandemics how have these events influenced our knowledge of the immune system? Examples will be the Black Plague, Cholera, Leprosy, Spanish Flu, H1N1, SARS 10. Treating immune disorders - the joys and pitfalls of the Pharmaceutical Industry.

2 Vitamins

3 Vitamins

4 Commercial Products

5 Clinical suggestions gene therapy v4sdgko

6 Clinical suggestions isolation The disorder -- severe combined immunodeficiency (SCID) -- compromises the immune system so severely that children can't fight off normally innocuous infection

7 Clinical suggestions bone marrow transplantation

8 Clinical suggestions bone marrow transplantation

9 Clinical suggestions use of biologics

10 Signaling or Cellular Communication Sequence in Innate Immunity Receptor TLR ligand (eg, LPS) or TNF Outside Kinase activator IKK Inside Inhibitor Transcription Factor IKK, I B kinase Beinke S. et al, Biochem J. 382, 393, 2004

11 Anti-TNF antibodies to soap Clinical suggestions use of biologics TNF cytokine that is causing active NF B activation and active inflammation /journal/v7/n11/full/nrrheum html

12 Clinical suggestion biologics for cancer Dr. Dennis Slamon Public Lecture on May 24 at 7 pm At Bernard Snell Hall Movie, Living Proof at Garneau at 730 on May 17 th Q&A to follow Type in on google crina ualberta /mor/mor html

13 Clinical suggestion small molecule inhibitors content/124/20/3040?ssochecked=true

14 Homeopath or alternative medicine Homeopathy, or homeopathic medicine, is a medical philosophy and practice based on the idea that the body has the ability to heal itself. Dates back to Hippocrates in 400 BC to treat mental illness with mandrake root Homeopathy believes that instead of trying to attack a specific problem, another strategy to re-establish health is to attempt to stimulate a person's own immune and defense system

15 Homeopath suggestions

16 Vitamins

17 10 ways to boost the immune system in kids Almonds are packed with vitamin E and manganese, a strong immune-boosting duo that both enhance natural killer cell activity Berries are full of antioxidants, which help your body fight oxidative stress caused by free radicals Yogurt - low sugar ones with probiotics can stimulate your immune system Salmon is rich in omega 3 fats. Not only are these fats essential for developing brains, they also reduce inflammation, which increases airflow and protects the lungs from colds and respiratory infections Eggs - have naturally occurring vitamin D and other immune-boosting nutrients, such as B vitamins and selenium Broccoli is a nutritional powerhouse with a number of immune system boosters, including vitamins C, A, and E and a number of antioxidants

18 10 ways to boost the immune system in kids Spinach is full of many of the vitamins and minerals that boost our immune systems including vitamin A, E, C, and K, folate, manganese, zinc, selenium, and iron. Sweet potatoes are high in beta-carotene that can increase the number of white blood cells and the activity of killer cells. Sweet potatoes are also a great source of vitamin C, which is another immune system enhancer. Pumpkin, sunflower, and flax seeds can boost their immune systems, a source of vitamin E, zinc, and omega 3 fatty acids, all of which help your immune system. Oats contain beta glucans, a component of fiber that activates killer cells. These are the cells that fight bacteria, viruses, and other intruders in our bodies.

19 Homeopath suggestions targets for Omega-3 Fatty Acids - Fish oils, seafood, walnuts, flax seeds and most nuts Folic Acid - in vitamin B9, broccoli, spinach, beans, lentils Uric acid (Arthritis, bone metastasis) Ginger helps reduce uric acid build up NF B - Curcumin/turmeric in indian curries & resveratrol [in grapes, plums and wine) NF B Green tea contains an active polyphenol that inhibits the activities of IL-1

20 Homeopath suggestions vitamins com/2013/07/23/the-immuneboosting-power-of-vitamin-c/

21 Homeopath suggestions vitamins Vitamin D Vitamin A supports by retaining moisture in mucous linings of mouth, throat, nose and other body parts. Vitamin E (IL-2 production) Vitamin B9 (Folic Acid) ironment/2011/1104/bonekey /full/bo nekey html

22 A balanced immune system