0400 Triad Profile. Metametrix Corporate Way Duluth, GA 30096
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1 3425 Corporate Way Duluth, GA Accession Number: Reference Number: Patient: Age: 48 Sex: Female Date of Birth: 02/05/1962 Date Collected: 12/7/10 Date Received: 12/8/10 Report Date: Telephone: Fax: Reprinted: Comment: 12/8/10 (770) (770) /2/ Triad Profile This report contains the following: 1. Laboratory data Organix Comprehensive Profile Amino Acid Analysis - 20 Plasma IgG4 Food Antibodies (90 Antigens) 2. Triad Profile Analyte Pattern Analysis To view your online Food Reaction Patient Guide, please visit our website at and select the Interpretive Guide tab on the top row navigation.
2 Date Received: 12/8/2010 Date Reported: 12/8/ Triad Profile Summary of abnormal results: Findings Intervention Options Metabolic Association Fatty Acid Metabolism Adipate High Carnitine, B2 Fatty acid oxidation Carbohydrate Metabolism Energy Production Markers Fumarate Hydroxymethylglutarate High High CoQ10 CoQ10 ATP production HMG-CoA reductase inhibition B-Complex Vitamin Markers Methylation Cofactor Markers Neurotransmitter Metabolism Markers Vanilmandelate Very Low 5-Hydroxyindoleacetate Low Oxidative Damage and Antioxidant Markers Detoxification Indicators Support Adrenal Function 5-HTP Epi- & Norepinephrine turnover inhibition Serotonin turnover inhibition Bacterial - General Benzoate p-hydroxybenzoate High High Glycine Probiotics Hepatic Phase II conjugation Intestinal bacterial overgrowth L. acidophillus/general bacteria Clostridial species Yeast/Fungal Essential Amino Acids Number of abnormal aminos 2 Customized free from amino acids Amino Acid insufficiency Neuroendocrine Metabolism Ammonia/Energy Metabolism Food Antibody Reactions (No. of foods) Mild (+1 and +2) 1 Moderate (+3 and +4) 2 Use Elimination Diet Use Elimination Diet Intestinal hyperpermeability Intestinal hyperpermeability
3 Total Number >= +1 3 Glutamine Intestinal hyperpermeability
4 Date Received: 12/8/2010 Date Reported: 12/8/2010 Organix Comprehensive - Urine Results are expressed as mcg/mg creatinine. Ranges: Ages 13 and over. Nutrient Markers Results Methodology: LC/Tandem Mass Spectroscopy, Colorimetric 95% Reference Interval Fatty Acid Metabolism (Carnitine & B2) Adipate 6.0 H <= Suberate <= Ethylmalonate 1.5 <= 6.3 Carbohydrate Metabolism (B1, B3, Cr, Lipoic Acid, CoQ10) 4 Pyruvate L-Lactate β-hydroxybutyrate <DL* Energy Production (Citric Acid Cycle) (B comp., Q10, Amino acids, Mg) Citrate Cis-Aconitate 51 H Isocitrate a-ketoglutarate <DL* <= Succinate <= Fumarate 0.67 H 0.59 <= Malate 0.4 <= Hydroxymethylglutarate 4.6 H <= 5.1 B-Complex Vitamin Markers (B1, B2, B3, B5, B6, Biotin) a-ketoisovalerate <DL* <= a-ketoisocaproate 0.06 <= a-keto-β-methylvalerate <DL* <= Xanthurenate 0.04 <= β-hydroxyisovalerate 2.5 <= 11.5 Methylation Cofactor Markers (B12, Folate) Methylmalonate 0.5 <= Formiminoglutamate 0.1 <= <= 6.4 <= 9.9 Page 1
5 Date Received: 12/8/2010 Date Reported: 12/8/2010 Methodology: LC/Tandem Mass Spectroscopy, Colorimetric Organix Comprehensive - Urine Ranges: Ages 13 and over. 95% Reference Interval Cell Regulation Markers Results Neurotransmitter Metabolism Markers (Tyrosine, Tryptophan, B6, antioxidants) 22 Vanilmandelate 0.6 L Homovanillate Hydroxyindoleacetate 1.7 L Kynurenate <= Quinolinate 1.4 <= Picolinate Oxidative Damage and Antioxidant Markers (Vitamin C and other antioxidants) 28 p-hydroxyphenyllactate <= Hydroxy-2-deoxyguanosine* 1.4 <= 7.6 * Units for 8-Hydroxy-2-deoxyguanosine are ng/mg creatinine. Toxicants and Detoxification Detoxification Indicators (Arg, NAC, Met, Mg and antioxidants) 30 2-Methylhippurate <= Orotate 0.09 <= Glucarate 2.9 <= a-hydroxybutyrate 0.3 <= Pyroglutamate Sulfate 1, , ,988 Page 2
6 Date Reported: 12/8/2010 Organix Comprehensive - Urine Ranges: Ages 13 and over. Compounds of Bacterial or Yeast/Fungal Origin Date Received: 12/8/2010 Methodology: LC/Tandem Mass Spectroscopy, Colorimetric Bacterial - general 36 Benzoate 3.6 H 0.6 <= Hippurate 59 <= 1, Phenylacetate <DL* <= Phenylpropionate <DL* <= p-hydroxybenzoate 2.50 H <= p-hydroxyphenylacetate <DL* <= Indican 38 <= Tricarballylate 0.49 <= 1.41 L. acidophilus / general bacterial 44 D-Lactate Clostridial species 45 3,4-Dihydroxyphenylpropionate 0.3 <DL* <= 7.0 <= 0.12 Yeast / Fungal D-Arabinitol Creatinine =195 mg/dl 7 <= 73 * <DL = less than detection limit Page 3
7 Amino Acid Analysis - 20 Plasma Ranges: Ages 13 and over. Date Received:12/08/2010 Date Reported: 12/08/2010 Methodology: ION Exchange HPLC Essential Amino Acids Limiting Amino Acids Lysine Methionine Tryptophan Branched Chain Amino Acids Isoleucine Leucine Valine Other Essential Amino Acids Phenylalanine Histidine Threonine Conditionally Essential Amino Acids Arginine Taurine Glycine Serine Results 95% umol/l Reference Interval L L Page 4
8 Date Received:12/08/2010 Date Reported: 12/08/2010 Amino Acid Analysis - 20 Plasma Ranges: Ages 13 and over. Methodology: ION Exchange HPLC Results umol/l Functional Categories Vascular Function Arginine Taurine % Reference Interval Neurotransmitters and Precursors Phenylalanine Tyrosine Tryptophan Glutamic Acid Taurine Sulfur Amino Acids (Glutathione - related) 21 Methionine Taurine Urea Cycle and Ammonia Detoxification Arginine Citrulline Ornithine Glutamine Asparagine Aspartic Acid 5.0 Ratios 29 Phenyalanine/Tyrosine Glutamic Acid/Glutamine Tryptophan/LNAA* *Large neutral amino acids (Leu+Ile+Val+Phe+Thr) <= Page 5
9 Date Received: 12/8/2010 Date Reported: 12/8/ IgG4 Food Antibodies (90 Antigens) Methodology: ELISA Results ng/ml Response Class Dairy/Meat/Poultry Beef Casein 32 Chicken Egg, White 10 Egg, Yolk 19 Lamb 18 Milk 210 Mod +3 Pork Turkey Fish/Shellfish Clam Codfish Crab Flounder Halibut Lobster Mackerel Oyster Salmon Shrimp Trout Tuna Fruits Apple Apricot Banana Blueberry Cantaloupe Cranberry Grape Grapefruit Honeydew Lemon Orange Peach Pear Pineapple Strawberry Watermelon Grains Barley Corn Oat Rice Rye Wheat Legumes Bean, String Lentil Lima Bean Navy Bean Pea, Green Peanut Pinto Bean Soybean Miscellaneous Aspergillus Black Pepper Chocolate Cinnamon Coffee Ginger Malt Tea Vanilla Yeast, Baker's Yeast, Brewer's Nuts/Seeds Almond Cashew Coconut Pecan Pistachio Sesame Sunflower Walnut Results ng/ml Response Class Mild Mod Page 6
10 Vegetables Asparagus Avocado Broccoli Cabbage Carrot Cauliflower Celery Cucumber Garlic Lettuce Mushroom Mustard Seed Olive Onion Pepper, Green Potato Spinach Sweet Potato Tomato Zucchini These test results are not for the diagnosis of disease. They are intended to provide nutritional guidelines to qualified healthcare professionals with full knowledge of patient history and concerns to assist in their design of an appropriate healthcare program. Class Definitions Class Negative Mild (+1/+2) Moderate (+3/+4) Severe (+5) Cutoffs / /900 > 900 Page 7
11 Triad Profile Analyte Pattern Analysis A multi-analyte report can provide greater insight about health risks and special nutrient needs. Patterns of abnormalities can reinforce the degree of significance indicated by a single measurement. Analytes from the various profiles in the Triad report are combined below into categories associated with clinical/metabolic conditions. The categories included cover the most common areas of concern relevant to these profiles. Above each thermometer are listed the analytes used to calculate the degree of significance. An X appears when the patient result is in the fifth quintile of the population. An additional H or L next to an analyte indicates that the patient result is outside the reference limit or interval for that analyte. The thermometer advances to the right as the number and severity of relevant abnormalities increases. The longer the filled bar, the greater the degree of significance or likelihood that a health threat may exist in that category. The preceeding laboratory reports provide the detail upon which these thermometers are based. Fatigue (Mitochondrial Impairment) Isoleucine L Leucine L Phenylalanine Adipate H Suberate akg Succinate Malate Xanthurenate MeMalonate FIGLU Low significance Mental/Emotional Tryptophan Tyrosine Xanthurenate MeMalonate FIGLU Quinolinate VMA L X 5-HIA L HVA Low significance Intestinal Hyperpermeability (Leaky Gut) Positive IgG scores of 2+ or higher were found for 2 foods. Low significance Digestive Insufficiency Histidine Isoleucine L Leucine L Lysine Methionine Threonine Valine MeMalonate Pyruvate akbmeval Glutamine Low significance Page 8
12 Triad Profile Analyte Pattern Analysis Toxic Exposure 2-MeHipp Glucarate Sulfate Orotate Citrate Cis-Aconitate H Isocitrate Quinolinate Low significance Mitochondrial Functional Impairment Adipate H Suberate Ethylmalonate Pyruvate L-Lactate β-hb Succinate Fumarate H Malate HMG H Low significance Amino Acid Insufficiency Arginine Histidine Isoleucine L Leucine L Lysine Methionine Phenylalanine Threonine Tryptophan Valine akg Succinate Sulfate Low significance Gut Dysbiosis D-Arabinitol PhAc PhProp phphac Indican Tricarb D-Lactate 3,4-DHPP Low significance Detoxification Capacity Methionine Glycine Taurine Sulfate Pyroglutamate AHB Low significance Page 9
13 Triad Profile Analyte Pattern Analysis Methylation Methionine Xanthurenate MeMalonate FIGLU Low significance Abbreviatio 2-MeHipp 5-HIA 8-OhdG AHB akbmeval AKG akicap akival BHB BHiVal 3,4-DHPP FIGLU Analyte Name 2-Methylhippurate 5-Hydroxyindoleacetate 8-Hydroxy-2-deoxyguanosine a-hydroxybutyrate a-keto-ß-methylvalerate a-ketoglutarate a-ketoisocaproate a-ketoisovalerate ß-Hydroxybutyrate ß-Hydroxyisovalerate 3,4-Dihydroxyphenylpropionate Formiminoglutamate Abbreviation HVA HMG IgG MeMalonate PhAc PhProp phbenz phphac phphlac Tricarb VMA Analyte Name Homovanillate Hydroxymethylglutarate Immunoglobulin G* Methylmalonate Phenylacetate Phenylpropionate p-hydroxybenzoate p-hydroxyphenylacetate p-hydroxyphenyllactate Tricarballylate Vanilmandelate * Thermometers are affected when more than nine foods cause reactions of +2 or higher. Page 10
14 0400 Triad Profile Ordered By: Customized Vitamin-Mineral Formula With knowledge of a patient's full medical history and concerns, the Triad Profile laboratory results may be used to help create an individually optimized nutritional support program. Based strictly on the results from this test, the summary table below shows estimates of nutrient doses that may help to normalize nutrient-dependent metabolic functions. All amounts are adult doses that should be reduced for children according to body weight. Customized Vitamin and Mineral Formulation Nutrients listed in this section are normally contained in a multi-vitamin preparation. "Base" amounts may be used for insurance of health even when no abnormalities are found. Customized preparations of the multi-vitamin/mineral formula shown below may be produced by compounding pharmacies. Base Daily Amounts Units Added Vitamin A* B-Carotene* Vitamin C Vitamin D* Vitamin E (Mixed Tocopherols) Vitamin K* Thiamin (B1) Riboflavin (B2) Niacin (B3) Pyridoxine (B6) 2500 IU 5500 IU 250 mg 400 IU 100 IU 100 mcg 5 mg 5 mg 25 mg 15 mg Folic Acid (or 5-Methyl-THF) 400 mcg 800 mcg Vitamin B12 Biotin Pantothenic Acid (B5) 50 mcg 100 mcg 25 mg Calcium citrate 500 mg 400 mg Iodine* Magnesium Zinc* Selenium Copper Manganese* Chromium Molybdenum* 75 mcg 250 mg 15 mg 100 mcg 1.5 mg 5 mg 200 mcg 25 mcg Boron* 1 mg * Nutrients with an asterisk are not modified based on the Triad test results. MM01
15 0400 Triad Profile Ordered By: Other Items Indicated for individual supplementation Various conditionally essential nutrients and other potentially beneficial interventions appear in this section only if relevant abnormalities are present. These ingredients are not included in the customized vitamin formula on the previous page. Amino acids listed on this page result from functional markers of individual amino acid insufficiency and do not reflect amino acids measured in plasma. Any amino acids that appear may be needed in addition to the customized amino acid formula on the following page. Item Amount Potential to Benefit from Probiotics Carnitine Mild 400 mg Coenzyme Q10 60 mg Glycine 3000 mg Need for Other Antioxidants Minimal Page 12
16 Customized Free-Form Amino Acids 30 - Day Amino Acid Powder Supplement Recommendation The table below shows a customized amino acid formula based on the results of your laboratory profile. The formula is optimized by adding amounts shown in the Grams Added column according to the relative positions of results found. Directions: Adults mix 1 and 1/2 measuring teaspoon (5g) in juice or water 2 times daily between meals as a dietary supplement, or as directed by a health care provider. Children under 12 years old: 3/4 teaspoon 1-2 times daily between meals. Children under 5 years old: Use 1/4 teaspoon, 1-3 times daily; adjust for body weight. Grams Added % of Formula Active mg/day L-Arginine HCl (80% active) L-Histidine HCl (74% active) L-Isoleucine ,101 L-Leucine ,442 L-Lysine HCl (80% active) L-Methionine L-Phenylalanine ,108 Taurine L-Threonine L-Tryptophan L-Valine Pyridoxal-5-phosphate Alpha-ketoglutaric acid Total grams added 41 Base Formula amount 259 Total Weight 300 L-5-Hydroxytryptophan This formula is intended to optimize essential and conditionallly essential amino acid intake. Other non-essential amino acids can be produced in human tissues. Pyridoxal-5-phosphate (an active form of vitamin B6) and alpha-ketoglutaric acid are key factors needed for the body's utilization of amino acids. The formula may be ordered as a powder that dissolves easily in beverages or may be added to foods such as applesauce. Other forms of supplemental dietary protein or amino acids may need to be restricted while using your customized formula. If enhanced energy levels prevent sleep, avoid bedtime use. This formula is provided as a starting point that may guide decisions about medical treatment based on the test results. It is derived only from the laboratory results included in this report. Final recommendations should be based on consideration of the patient's medical history and current clinical condition. In addition to the above customized amino acid formula, this patient may benefit from further use of single amino acids, as evidenced by profiles other than plasma amino acids. See the category, "Other Indicated Nutrients" on your Supplement Recommendation Summary Page. Page 13
0410 Triad Bloodspot Profile
Accession Number: Order Number: Reference Number: Patient: Age: Date of Birth: Date Collected: Report Date: Telephone: Fax: Reprinted: Comment: 0410 Triad Bloodspot Profile This report contains the following:
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Accession Number: Order Number: Reference Number: Patient: Age: Sex: Date of Birth: Date Collected: Date Received: Report Date: Telephone: Fax: Reprinted: Comment: 0400 Triad Profile This report contains
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Accession #: Order #: Reference #: Patient: Date of Birth: Age: Sex: Date Collected: Date Received: Telephone: Fax: Organix Interpretation Organix Interpretive Guide is downloadable at: www.metametrix.com/files/test-menu/interpretive-guides/organix-ig.pdf
0091 Organix Comprehensive Profile - Urine
3425 Corporate Way Duluth GA 30096 USA 770.446.5483 Fax: 770.441.2237 www.gdx.net/www.metametrix.com Ordering Physician: Accession #: Reference #: Patient: Date of Birth: Age: Sex: Reprinted: 07/04/2001
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Ordering Physician: 255252-279741 Via Borin 48 31100 Treviso Number: Age: 43 Sex: F Date of Birth: 03/01/1964 Date Collected: 12/12/07 Date Received: 12/17/07 Telephone: Fax: Summary of abnormal results:
0291 Organix Basic Profile - Urine
Accession #: Order #: Reference #: Patient: G1234567 Date Collected: Date Received: Date of Report: 04/03/2012 Date of Birth: 02/05/1962 Telephone: 7704464583 Ordering Physician: Age: Sex: 50 Female Fax:
0291 Organix Basic Profile Summary of abnormal results:
Ordering Physician: 250200-274226 Reference Number: Age: 57 Sex: F Date of Birth: 12/25/1949 Date Collected: 11/18/07 Date Received: 11/18/07 Report Date: Telephone: Fax: Reprinted: 12/5/07 7704465483
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Ordering Physician: Metametrix 1234 Main St. Anywhere, GA 30096 Reference Number: Age: 50 Sex: Female Date of Birth: 02/05/1962 Date Collected: 6/12/12 Date Received: 6/13/12 Report Date: Telephone: Fax:
0490 ION with Amino Acids 40 Profile
Accession Number: Order Number: Number: Patient: Age: Sex: Date of Birth: Date Collected: Report Date: Telephone: Fax: Reprinted: Comment: 0490 ION with Amino Acids 40 Profile Amino Acids 40 Profile -
Essential Amino Acids
3425 Corporate Way Duluth, GA 30096 Patient: SAMPLE PATIENT DOB: Sex: MRN: 3100 ION Profile - Blood / Urine Amino Acids 20 Profile - Plasma Methodology: High Performance Liquid Chromatography s: Ages 13
4315 NY Designs for Health Metabolic Profile
Ordering Physician: Metametrix Staff & Family 3425 Corporate Way Duluth, NY 30096 Accession Number:A0909030008 Reference Number: Age: 47 Sex: Female Date of Birth: 02/05/1962 Date Collected: 9/2/09 Date
0490 ION with Amino Acids 40 Profile
Metametrix 1234 Main St. Anywhere, GA 30096 Accession Number: Order Number: G1234567 Number: Patient: Age: 51 Date Collected: Report Date: Telephone: Fax: Reprinted: Comment: Sex: 4/3/13 Date Received:
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3425 Corporate Way Duluth, GA 30096 3102 ION Profile with Amino Acids 40 - Blood/Urine Amino Acids 40 Profile - Plasma Methodology: High Performance Liquid Chromotography s: Ages 13 and over. Limiting
588G: Dietary Antigen Testing: Sensitivity and Complement 1/5. Dietary Antigen Exposure by Food Group
PATIENT NAME: CLINIC: DOB: SAMPLE DATE: RECEIVE DATE: REPORT DATE: R //2 /28/27 /29/27 /3/27 Dunwoody Labs 9 Dunwoody Park Suite 2 Dunwoody, GA 3338 USA Phone: 6787366374 Fax: 776747 Nine Dunwoody Park,
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Ordering Physician: Metametrix 3425 Corporate Way Duluth, GA 30096 Accession Number:A0909030010 Reference Number: Age: 47 Sex: Female Date of Birth: 02/05/1962 Date Collected: 9/2/09 Date Received: 9/3/09
0490 ION with Amino Acids 40 Profile
Accession Number: Order Number: Number: Patient: Age: Sex: Date of Birth: Date Collected: Report Date: Telephone: Fax: Reprinted: Comment: 0490 ION with Amino Acids 40 Profile Amino Acids 40 Profile -
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0290 Cardio/ION Profile
3425 Corporate Way Duluth GA 30096 USA 770.446.5483 Fax: 770.441.2237 www.gdx.net/www.metametrix.com Accession Number: Number: Patient: Age: Date of Birth: Date Collected: Report Date: Telephone: Fax:
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