3B/4B (repeat): Tending the Garden Within: Cultivating GI Wellness

Transcription

1 SIMPLY SPICY 2017 July 8-9, 2017 Sagebrush Inn & Suites, Taos, New Mexico 3B/4B (repeat): Tending the Garden Within: Cultivating GI Wellness Sally Fisher, MD & Satkirin Khalsa, MD Sunday, July 9, :30 p.m. 3:00 p.m. 3:15 p.m. 4:45 p.m.

2 Tending The Garden Within: Cultivating GI Wellness Satkirin K. Khalsa, MD Simply Spicy July 9, 2017 Objectives Review the Brain-Gut & Microbiota Axes Discuss the physiology of breathing Neuro-endocrine mechanical pathways and functions Review pulmonary anatomy Correlate Brain-Gut-Microbiota Axis & Lung physiology Inflammatory cascade Neuro-endocrine modulation Microbiota harmony Brain-Gut-Microbiota Axis Stress Traumatic Life event Physical Emotional Situational/environmental Inflammatory Cascade Bi-directional central integrative interactions Brain-Gut-Microbiota-Gut-Brain 1

3 Nervous Gut Brzozowski B., et al. Mechanisms by which stress affects the Inflammatory Bowel Disease (IBD): Role of Brain- Gut Axis Current Neuropharmacology 2016; 14: Bi-Directional Complexities Brzozowski B., et al. Mechanisms by which stress affects the Inflammatory Bowel Disease (IBD): Role of Brain- Gut Axis Current Neuropharmacology 2016; 14: Stress Tentacles Konturek PC, et al. Stress and the Gut: Pathophysiology, Clinical Consequences, and Diagnostic Approach and Treatment Options Journal of Physiology and Pharmacology 2011; 62(6):

4 Symphony of Nerves and Microbes Konturek PC, et al. Stress and the Gut: Pathophysiology, Clinical Consequences, and Diagnostic Approach and Treatment Options Journal of Physiology and Pharmacology 2011; 62(6): Dysregulation of Microbiota via BGA Konturek PC, et al. Stress and the Gut: Pathophysiology, Clinical Consequences, and Diagnostic Approach and Treatment Options Journal of Physiology and Pharmacology 2011; 62(6): Breathing Anatomy Diaphragm and the crural diaphragm Slow adapting stretch receptor distribution Vagal Nerve: Afferent/efferent neurons & signaling pathways 3

5 Breathing A&P Anatomy Posture Chest Capacity Intra-thoracic Pressure and Atmosphere Alveolar Sensors Slow adapting stretch receptors Paced breathing Baroreceptor modulation Heart Rate Variability sensitivity Breathing & Brain-Gut Axis Crural diaphragm Afferent/Efferent Neurons of the Autonomic Nervous System Lower esophageal sphincter tone Mechanical barrier for acid reflux Physiology of Long Deep Breathing Recruit & expand more alveoli Stimulate slow adapting stretch receptors: SARS Baroreceptors in carotid arteries detect stretch Baroreceptors communicate through neuroendocrine pathways to affect kidney function Salt and water filtration increased as: Autonomic nervous system altered: Sympathetic tone decreases, as parasympathetic tone is favored 4

6 Autonomic Tone in Parasympathetic Favor S Anatomy Larynx- breathing tube Anatomy: chest Cavity 5

7 Anatomy: The Diaphragm Diaphragm Muscle, View From Below When Parasympathetic is Favored: Overall Decrease in Vascular tone Muscle tension HR, Blood Pressure Improve HR variability and synchronicity Bernardi L, et al Effect of rosary prayer and yoga mantras on autonomic cardiovascular rhythms: Comparitive Study BMJ 2001 Dec; 323:

8 Practice Makes Perfect Back to basics: baby posturing, belly breathing, Practice Retrain body to breathe long, deep At Baseline: Clavicle angle Distance between head of clavicles, articulation to sternum Ribs, Intercostals Shoulders internal rotation Apex of lung situated. 7

9 External rotation of shoulders (anatomic): Clavicle angled up Distance between head of clavicles, articulation to sternum increased Apex of lung situated. higher Breathe Control, with Postures Patients can use at any time Always in back pocket Useful, immediate, effective tool Can be done anywhere It s free And..we re already breathing Happy Humans Happy Microbiota Happy Gut Thank You! 8