thinkdelirium 4th Annual Meeting of the American Delirium Society Delirium: From Molecules to Clinical Implementation

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1 ISSUE JANUARY 2012 ISSUE 2 07 May 2014 thinkdelirium NEWSLETTER OF THE AMERICAN DELIRIUM SOCIETY 4th Annual Meeting of the American Delirium Society Delirium: From Molecules to Clinical Implementation Embassy Suites Baltimore- Inner Harbor and Grand Historic Venue Baltimore, Maryland June 1-3, 2014 This issue P Pre- Conference Program P Conference Program P9 P10 Safe Management of Behavioral Disorders in Extended Care Survey & New Book Registration Now Open upcoming-ads-events Joseph H. Flaherty, MD Geriatrics Division Saint Louis University Editor-in-Chief 1

2 Sunday, June 1, 2014 Time Session Speaker REGISTRATION Pre-Conference Workshop 1 Delirium 101: Introduction to Delirium Introduction to the course & faculty Introduction to Delirium Epidemiology Key features of Delirium Including DSM-5 Criteria & Subtypes Morbidity & Mortality Predisposing and Precipitating Factors Delirium Pathophysiology Neurobiology of Delirium Diagnosing Delirium Diagnostic Tools Mental Status as a Vital Sign Delirium vs. Dementia vs. Depression Delirium: Cognitive Sequelae Interaction Between Cognitive Deficit & Delirium Course Director José R. Maldonado MD FAPM FACFE José R. Maldonado MD FAPM FACFE José R. Maldonado MD FAPM FACFE Alasdair MacLullich MB ChB MRCP PhD James L. Rudolph MD MS Yesne Alici MD Q & A Entire Panel BREAK Delirium: A Nursing Perspective th Annual Meeting of the American Delirium Society Pre-Conference June 1, 2014 Delirium Assessment and Screening -- CAM & CAM-S: The Most Widely- Used Delirium Assessment Methods Delirium Assessment & Screening -- DSM-5 & Delirium Assessment Guidelines (including 4AT) Joyce Parks MSN RN-BC PMHCNS- BC Joseph H. Flaherty MD Q & A Entire Panel LUNCH not supplied by ADS Alasdair MacLullich MB ChB MRCP PhD Registration:

3 4 th Annual Meeting of the American Delirium Society Pre-Conference June 1, 2014 Sunday, June 1, 2014 ` Pre-Conference Workshop 2 ICU Delirium: An Old Syndrome with New Solutions Course Directors Dale M. Needham FCA MD PhD Babar A. Khan MD MS Opening Remarks Dale M. Needham FCA MD PhD Delirium in the ICU - A Patient s Perspective Cheryl Misak DPhil Epidemiology and Consequences of ICU Delirium Timothy D. Girard MD MSCI Q & A Society of Critical Care Medicine s 2013 Guidelines on Pain, Agitation, and Delirium in the ICU - What You Need to Know Delirium Screening in the ICU - Practical Tips for Making it Work BREAK Delirium and its Relationship with Post-ICU Long-Term Cognitive Impairment Improving Sleep in the ICU to Reduce Delirium Q & A Implementing the ABCDE Bundle to Reduce ICU Delirium Implementing Early Mobilization in the ICU to Reduce Delirium Babar A. Khan MD MS Nathan E. Brummel MD MS MSCI Moderator: Dale M. Needham FCA MD PhD Timothy D. Girard MD MSCI Biren Kamdar MD MBA Lauren M. King RN Leanne M. Boehm MSN RN ACNS- BC Jennifer M. Zanni PT DScPT Moderator: Dale M. Needham FCA MD PhD Closing Comments Dale M. Needham FCA MD PhD Poster Setup ADS 4 th Annual Meeting Welcome Reception Registration:

4 4 th Annual Meeting of the American Delirium Society Conference June 2 3, 2014 Monday, June 2, 2014 Time Session Speaker Welcome REGISTRATION Breakfast Session with Junior Faculty (by invitation) Presidential Addresses from ADS and EDA BREAK Scientific Session 1 Risk Factors and Pathogesis of Delirium Decreased Functional Connectivity and Loss of Small World Topology in the EEG of Postoperative Patients with Delirium Delirium Risk Factors in Older Emergency Department Patients Development and Validation of Daily Acute Brain Dysfunction Prediction Model in the Intensive Care Unit Does Apolipoprotein E Genotype Increase Risk of Postoperative Delirium? Benzodiazepine Administration and the Association with Delirium in the ICU: A Prospective Cohort Study Subtypes of Delirium During Critical Illness as Predictors of Long-Term Cognitive Impairment BREAK Plenary Session 1 Delirium Research: Policy and Advocacy to Bedside Implementation Research in the Time of Big Data Benefits to the Use of Common Measures Advocating for Dementia and Delirium Research in Europe Rakesh C. Arora MD PhD FRCSC FACS President Elect and Conference Planning Committee Chair Karin J. Neufeld MD MPH Alasdair MacLullich MB ChB MRCP PhD Babar A. Khan MD MS Jeffrey H. Silverstein MD MS AGSF Arjen Slooter MD PhD Jin Ho Han MD MSc Eduard E. Vasilevskis MD Sarinnapha Vasunilashorn PhD Irene J. Zaal MD PhD[c] Timothy D. Girard MD MSCI Session Chair Christine M. Waszynski APRN Molly V. Wagster PhD Alasdair MacLullich MB ChB MRCP PhD Delirium in a Hospital System George E. Taffet MD LUNCH POSTER SESSION

5 4 th Annual Meeting of the American Delirium Society Conference June 2 3, 2014 Monday, June 2, Early Afternoon Concurrent Sessions Symposium 1: Diagnosing and Managing Delirium in Challenging Populations Session Chair Pratik Pandharipande MD MSCI Delirium in the Neurologically Injured Patient Andrew M. Naidech MD MSPH Delirium in Infants and Toddlers Heidi A. B. Smith MD MSCI FAAP Delirium in Patients with Mental Illnesses Karin J. Neufeld MD MPH Delirium in Patients with Dementia Philippe Voyer RN PhD Q & A Moderator: Pratik Pandharipande MD MSCI Early Afternoon Concurrent Sessions Symposium 2: Near Infrared Spectroscopy Measurement of Cerebral Perfusion and Delirium Charles H. Brown MD Frederick E. Sieber MD Cerebral Oximetry and Post-Cardiac Surgery Tanya Mailhot RN BSc PhD[c] Delirium Intraoperative Blood Pressure Autoregulation and Post-Operative Delirium The Use of NIRS in the CVICU Q & A Cerebral Oximetry and Delirium in Patients Requiring 1 Lung Ventilation BREAK Charles W. Hogue MD Rakesh C. Arora MD PhD FRCSC FACS Monique L. Roberts BA Moderators: Charles H. Brown MD Frederick E. Sieber MD Q & A Entire Panel BREAK RECEPTION Hosted by the Johns Hopkins Delirium Consortium Registration:

6 4 th Annual Meeting of the American Delirium Society Conference June 2 3, 2014 Monday, June 2, Q & A Late Afternoon Concurrent Sessions Symposium 3: Interdisciplinary Management of Delirium in Palliative Care: Collaboratively Building the Evidence Base An Overview of Delirium Research Priorities in Palliative Care Research Relevant to Nursing Practice in Delirium Recognition and Assessment in Palliative Care Inpatient Settings A Hospital-wide, Multidisciplinary Delirium QI initiative, Relevant to Screening and Non-Pharmacological Interventions for Elderly Inpatients Results of a Randomised Controlled Trial of Pharmacological Interventions for Targeted Delirium Symptoms An Overview of Evidence for Delirium Management in the Last Days of Life Late Afternoon Concurrent Sessions Symposium 4: Delirium 201: Advanced Course on Delirium Management Non-Pharmacological Approaches Prophylaxis Treatment Pharmacological Management of Delirium Prophylaxis Treatment Jane L. Phillips RN BA Sc (Nur) PhD Annmarie Hosie MPCAC BHlthSc (Nurs) Peter Lawlor MD MMedSc Annmarie Hosie MPCAC BHlthSc (Nurs) Michelle T. Weckmann MD MS Meera R. Agar MBBS MPC FRACP FAChPM PhD Shirley Bush MBBS DRCOG DCH MRCGP Dip Pall Med FAChPM Moderator: Jane L. Phillips RN BA Sc(Nur) PhD Session Chair José R. Maldonado MD FAPM Joseph Flaherty MD Q & A Entire Panel BREAK José R. Maldonado MD FAPM FACFE RECEPTION Hosted by the Johns Hopkins Delirium Consortium Registration:

7 4 th Annual Meeting of the American Delirium Society Conference June 2 3, 2014 Tuesday, June 3, 2014 Time Session Speaker REGISTRATION Introduction of Keynote Speaker Karin J. Neufeld MD MPH The Conundrum of ICU Delirium: Measurement, Outcomes, and Patient Autonomy Plenary Session 2 Brain Injury: Local and Systemic Considerations Cheryl Misak DPhil Noll L. Campbell PharmD Edward R. Marcantonio MD SM Using Biomarkers to Subtype Brain Disease Heterogeneity: The Case of Dementia Constantine G. Lyketsos MD MHS Neural Basis of Delirium: Insights from Anatomical and Functional Neuroimaging Robert D. Stevens MD Blood Brain Barrier in Delirium Christopher Hughes MD BREAK Late Morning Concurrent Session Workshop: An Innovative Approach to Delirium Mangagement An Innovative Approach to Delirium Management Late Morning Concurrent Session Roundtable Discussion: Delirium Measurement LUNCH POSTER SESSION AND AWARDS Session Director Clay R. Angel MD Faculty: Clay R. Angel MD Kristen B. Brooks MD Rakesh C. Arora MD PhD FRCSC FACS Alasdair MacLullich MB ChB MRCP PhD Edward R. Marcantonio MD SM

8 4 th Annual Meeting of the American Delirium Society Conference June 2 3, 2014 Tuesday, June 3, Scientific Session 2 Delirium Assessment and Outcomes Duration of Subsyndromal Delirium, Institutionalization, Mortality and Cognitive Impairment Following Critical Illness Preventing ICU Subsyndromal Delirium Conversion to Delirium with Low Dose IV Haloperidol: A Double-Blind, Placebo-Controlled Pilot Study Use of Parecoxib as an Adjuvant to Intravenous Morphine Analgesia Decreases the Incidence of Delirium in Elderly Patients after Orthopedic Surgery: A Randomized Control Study Detection and Prevention of Delirium Among Home-Dwelling Older Adults After Recent Hospitalization or Acute Illness: A Randomized Controlled Pilot Study Recent Hospitalization or Acute Illness: A Randomized Controlled Pilot Study Can There be a Diagnostic Test for Delirium Superimposed on Dementia? CONFERENCE ADJOURNMENT Michael A. LaMantia MD MPH Marianne Shaughnessy PhD CRNP Nathan E. Brummel MD MS MSCI John W. Devlin PharmD Dong-Liang Mu, MD Henk Verloo RN PhD[c] O. Joseph Bienvenu, MD, PhD Gideon A. Caplan MBBS MD FRACP Next year, June 2015 ADS will be in Baltimore, MD again please join us! Please feel free distribute this newsletter to clinical and administrative teams that you believe would benefit from the opportunity to meet like-minded clinicians and scientists from many different disciplines and specialties; develop friendships and research partnerships to improve the care of your patients at your institution. Sincerely and many thanks in advance, Rakesh C. Arora, Chair of the Conference Planning Committee and President Elect of the American Delirium Society

9 Attention: Extended Care Administrators and Staff (concurrently offered with the 4th Annual Conference additional fee required) Safe Management of Behavioral Disorders in Extended Care Monday, June 2, am - 12pm Improve Dementia Care and Reduce Unnecessary Use of Antipsychotic Medications in Your Facility Tools you can use today! This workshop will provide attendees with: 1) an understanding of how and why these drugs have been used to manage behavioral symptoms and the risks associated with their use in older adults, 2) innovative approaches to managing challenging behaviors, 3) insight into the current regulatory environment, and 4) tools for effectively managing behavioral disorders and maintaining a safe environment of care for both residents and staff. Faculty: James Rudolph, MD Geriatrician/Researcher in the VA Boston Healthcare System. Ann Kolonowski, PhD, RN, FGSA, FAAN Professor in the College of Nursing; Penn State University. Barbara Resnick, PhD, RN, CRNP, FAAN, FAANP is a Professor University of Maryland School of Nursing. Alice Bonner, PhD, RN, GNP Associate Professor at Northeastern University School of Nursing and former Monday June 2, 2014 Ionic Room (3rd Floor, Grand Historic Venue) 7:30-8:00 Registration 8:00-8:10 Welcome and Introductions 8:10-9:00 Describe Dangerous Dilemmas: Delirium, Dementia, and Drugs - James Rudolph 9:00-9:55 A Toolkit for Innovative Approaches to Managing Challenging Behaviors - Ann Kolanowski and Barbara Resnick 10:00-10:30 Break/Exhibits 10:30-11:30 Regulatory issues in the care of nursing home residents with dementia and delirium: updates on the CMS National Partnership and Implications for Practice - Alice Bonner 11:30-12:00 Panel/Case Discussion 12:00 Evaluation and Adjourn The American Delirium Society Mission: The goals of the American Delirium Society are to foster research, education, quality improvement, advocacy & implementation science to minimize the impact of delirium on short- and long-term health and well being, and the effects of delirium on the health care system as a whole. ADS President, Karin Neufeld MD MPH,

10 May 2014 ISSUE 07 thinkdelirium Dear EDA-ADS members and friends, Although there have been many advances in our knowledge of delirium there are still substantial uncertainties and a lack of consensus on the diagnosis of delirium superimposed on dementia (DSD). The European Delirium Association (EDA) and the American Delirium Society (ADS) have been spreading the knowledge of delirium across the world. The EDA and the ADS have decided to conduct a survey to help understand the range of opinions among mailing list members and other interested parties on various aspect of DSD diagnosis. We greatly appreciate your expertise and we believe that this Survey will provide a significant advancement in the knowledge of DSD. The results of this survey will be presented at the next EDA conference. You can find the survey following this link: The survey includes 26 questions and takes less than 10 minutes to be completed. We are very grateful for your time and we are looking forward to receiving your essential contribution and seeing you in Baltimore (Maryland, USA) on June 1-3 for the ADS 2014 meeting and in Cremona (Italy) on November 6 th -7 th for the EDA 2014 meeting. Kind Regards, Alessandro Morandi, MD, MPH Board Member, EDA Alasdair MacLullich, MRCP (UK), PhD President, EDA Karin Neufeld, MD, MPH President, ADS Brain dysfunction is a major clinical problem in intensive care, with potentially debilitating long-term consequences for post-icu patients of any age. The resulting extended length of stay in the ICU and post-discharge cognitive dysfunction are now recognized as major healthcare burdens. This comprehensive clinical text provides intensivists and neurologists with a practical review of the pathophysiology of brain dysfunction and a thorough account of the diagnostic and therapeutic options available. Initial sections review the epidemiology, outcomes, relevant behavioral neurology and biological mechanisms of brain dysfunction. Subsequent sections evaluate the available diagnostic options and preventative and therapeutic interventions, with a final section on clinical encephalopathy syndromes encountered in the ICU. Each chapter is rich in illustrations, with an executive summary and a helpful glossary of terms. Brain Disorders in Critical Illness is a seminal reference for all physicians and neuroscientists interested in the care and outcome of severely ill patients.