Curriculum Vitae Mr. N. K. Patel

Transcription

1 Curriculum Vitae Mr. N. K. Patel BSc (Hons), MBBS (Hons), FRCS (Neuro.Surg) 1

2 PERSONAL DETAILS Name Nationality Address PATEL Nikunj Kantilal British Department of Neurosurgery, Frenchay Hospital, Bristol BS16 1LE, United Kingdom GMC EDUCATION Epsom College, Epsom, Surrey Charing Cross & Westminster Medical School QUALIFICATIONS B.Sc. in Basic Medical Sciences with Anatomy - 1st Class Honours 1994 M.B.B.S. with Pathology Honours 1996 Jan Primary F.R.C.S. (England) 1996 U.S.M.L.E. (United States Medical Licensing Examinations) 1998 April F.R.C.S. (England) 2004 August F.E.A.N.S. (Fellowship of the European Association of Neurological Surgeons) 2004 October F.R.C.S. (Neuro.Surg.) 2

3 AWARDS AND DISTINCTIONS Neurosurgical Hunterian Professorship in Neurosurgery Royal College of Surgeons of England 2003 EANS Aesculup Research Award (European Association of Neurological Surgeons) 2003 Philip C. Gildenberg Resident Award for Stereotactic and Functional Surgery (American Association of Neurological Surgeons) MRC Fellowship for Functional Neurosurgery (REF: G ) 2002 South-West Neurosciences Association (SWENA) Presentation Prize Education 1994 Distinction in Pathology (M.B.B.S. Part IV) 1993 The Royal College of Pathologists Elective Bursary 1991 Intercalated B.Sc. 1 st Class Honours MRC Scholarship for B.Sc. Course 1990 Harry Barkley Biochemistry and Immunology Prize Charing Cross & Westminster Medical School Entrance Scholarship MEMBERSHIP OF PROFESSIONAL BODIES General Medical Council Principal list Medical Defence Union No J British Medical Association Fellow of the Royal Society of Medicine Member of the Worshipful Society of Apothecaries of London Associate Member of the Society of British Neurological Surgeons 3

4 Member of the Global College of Neuroprotection and Neuroregeneration Faculty Member for the European Society for Stereotactic and Functional Neurosurgery APPOINTMENTS AND EXPERIENCE A. Current Position 09/05 Consultant Neurosurgeon Department of Neurosurgery, Frenchay Hospital, Bristol B. Additional Positions Hunterian Professorship, Royal College of Surgeons of England Clinical Lecturer to the University of Bristol Honorary Consultant to the University of Kentucky, Lexington, USA C. Higher Surgical Training 02/99-08/05 Neurosurgery Specialist Registrar Department of Neurosurgery, Frenchay Hospital, Bristol Professor H. Coakham, Mr. R. Nelson, Mr. D. Sandeman, Mr. S. Gill, Mr. I. Pople, Mr. G. Malcolm, Mr. N. Patel, Mr. D. Porter 03/02 02/03 Functional Neurosurgery Fellowship Department of Neurosurgery, Frenchay Hospital Mr. S. Gill 01/02 02/03 MRC Clinical Research Fellowship PDSURG MRC Trial MRC Clinical Trials Unit, University of Birmingham 03/01 02/02 Functional Neurosurgery Research Registrar Department of Neurosurgery, Frenchay Hospital Mr. S. Gill D. Basic Surgical Training 4

5 11/98 1/99 Intensive Care: SHO (3 months) John Farman Intensive Care Unit, Addenbroke s Hospital, Cambridge Dr. G. Park, Dr. M. Lindop, Dr. K. Gunning, Dr. V. Navapurkar 2/98 7/98 General and Breast and Gastrointestinal surgery: SHO (6 months) Norfolk and Norwich Hospital, Norwich, Mr. D. Ralphs 2/96-1/98 OXFORD BASIC SURGICAL TRAINING ROTATION: 8/97-1/98 General and Vascular surgery: SHO (6 months) John Radcliffe Hospital, Oxford, Professor P. Morris, Mr. J. Collin, Miss L. Hands 2/97-7/97 Neurosurgery: SHO (6 months) Radcliffe Infirmary Hospital, Oxford, Mr. R. Kerr, Mr. C. Adams, Mr. P. Teddy, Mr. T. Aziz, Mr. T. Cadoux-Hudson 11/96-1/97 Trauma Surgery: SHO (3 months) John Radcliffe Hospital, Oxford, Mr. C. Bulstrode, Mr. R. Handley, Mr. R. Keys, Mr. C. Oliver, Mr. P. Wilde, Mr. K. Willett 8/96-10/96 Orthopaedics: SHO (3 months) Nuffield Orthopaedic Hospital, Oxford, Mr. P. McLardy-Smith, Mr. C. Dodd 2/96-7/96 Accident and Emergency: SHO (6 months) Wycombe General Hospital, High Wycombe, Mr. D. Small, Mr. D. Potts E. Pre-registration Posts 2/95-7/95 General Medicine and Neurology: House Physician (6 months) Royal Surrey County Hospital, Guildford, Dr. M. J. Smith, Dr. P. Trend, Dr. M. Gross 8/94-1/95 General Surgery: House Surgeon (6 months) Queen Mary s University Hospital, Roehampton, Mr. J. S. Kirkham E. Teaching 8/95 2/96 Anatomy Prosectorship (6 months) Department of Human Anatomy, Oxford University. 2/96 7/97 College Lecturer in Human Anatomy Worcester College, Oxford University. 02/02 Clinical Lecturer in Neurosurgery Clinical Medical Students, University of Bristol 5

6 Nursing Students, University of West England 8/04 European Society for Stereotactic and Functional Neurosurgery Teaching Faculty Member F. Courses Attended 2007 Occipital Nerve Stimulation for the Treatment of Chronic Intractable Headaches, Boston Scientific, Lucerne 2007 Spinal Cord Stimulation for Chronic Low Back Pain, Boston Scientific, Lucerne 2006 The Balloon Kyphoplasty Surgeon Training Program, Leiden 2006 Trabecular Metal Technology Trans-lumbar Interbody Fusion Workshop, Paris 2006 Minimally Invasive Spine Surgery: Innovative treatment methods in lower lumbar spine surgery, Bordeaux 2005 Management Course for Specialist Registrars, PasTest, London 2004 Neurosurgery Specialist Fellowship Course, Royal London Hospital 2004 Workshop on Neuroprotection and Neurorestoration, Member of Faculty, European Society for Stereotactic and Functional Neurosurgery, Vienna 2004 Instruction in Advanced Powered Surgical Instrumentation for Neurosurgical Procedures, Midas Rex Institute 2004 European Association of Neurosurgical Surgeons Course, Kracow Brain Tumours and Paediatric Neurosurgery 2003 European Association of Neurosurgical Surgeons Course, Amsterdam Vascular Neurosurgery 2002 European Association of Neurosurgical Surgeons Course, Rome: Spine and Peripheral Nerve Surgery 2001 European Association of Neurological Surgeons Course, Prague: Functional Neurosurgery, Head Injury and Paediatric Neurosurgery 2000 Movement Disorders: Pathophysiology, Diagnosis and Treatment, Congress of Neurological Surgeons Annual Meeting, San Antonio, Texas 1998 Whipps Cross Advanced Surgery Course 1997 ALS, Radcliffe Infirmary Hospital, Oxford 1996 Popumet, for safety in use of radiation, Churchill Hospital, Oxford 1996 RCS Basic Surgical Skills Course, St. Mary s Hospital, London 6

7 1996 ATLS, Stoke Mandeville Hospital, Aylesbury RESEARCH EXPERIENCE A. Towards Degree B.Sc.: Basic Science Research Project: The Role of N-Methyl-D-Aspartate Receptors in Mediating Changes Induced by Neuronal Injury in Rodent Model of Alzheimer s disease M.D.: Clinical Science Research Project: A Pilot Study to Assess the Safety and Efficacy of Chronic Intraputaminal Glial Cell Line-Derived Neurotrophic Factor (GDNF) for the Treatment of PD B. Current Projects Functional Neurosurgery Optimization of MRI localization of deep brain targets Pain Deep Brain Stimulation for Pain: Deep brain stimulation for peripheral de-afferentation pain: A comparative clinical outcome and functional mechanism trial of peri-ventricular grey/medial thalamus versus sensory lateral thalamic stimulation application submitted for MRC funding (Lead Investigator) Spinal Cord Stimulation for Neuropathic Pain Disorders: Understanding pain mechanisms through functional imaging changes with spinal cord stimulation Movement Disorders Glial Cell Line-Derived Neurotrophic factor (GDNF) treatment for Parkinson s disease Deep brain stimulation for Parkinson s disease, Dystonia and Essential Tremor Randomized Cross-over Study Comparing Centromedian/Parafascicular versus Caudal Zona Incerta Stimulation for PD trial sponsored by Medtronic Inc. PDSURG MRC Trial: A large randomised long-term assessment of the relative effectiveness of surgery for PD (Investigator and MRC Clinical Research Registrar: Jan 2002 March 2003) Surgery for Psychiatric Disease Deep Brain Stimulation in Treatment Refractory Major Depressive Disorder: a pilot study Deep brain stimulation for severe depression: Phase II study sponsored Advanced Neuromodulation Systems Inc. 7

8 Spinal Surgery Long-term follow-up study for cervical arthroplasty C. Publications related to MD Thesis 1. Direct brain infusion of glial cell line-derived neurotrophic factor (GDNF) in Parkinson s disease. Gill SS, Patel NK, Hotton GR, O Sullivan K, McCarter R, Bunnage M, Brooks DJ, Svendsen CN, Heywood P Nature Medicine. 2003; 9(5): Intraparenchymal Delivery of GDNF towards a treatment for Parkinson s Disease (A Review) Patel NK, Gill SS Gene Therapy and Molecular Biology. 2004; 8: Intraputamenal infusion of GDNF in Parkinson s disease: A two year outcome study Patel NK, Hotton GR, Bunnage M, Plaha P, Brooks DJ, Svendsen CN, Heywood P, Gill SS Annals of Neurology. 2005; 57(2): Glial cell line-derived neurotrophic factor induces neuronal sprouting in human brain Love S, Plaha P, Patel NK, Hotton GR, Brooks DJ, Gill SS Nature Medicine. 2005; 11(7): GDNF delivery for Parkinson s disease (Chapter) Patel NK, Gill SS Acta Neurochirurgica Supplement. 2007; 97(2): D. Other Publications 1. Excitotoxin Induction of Ornithine Decarboxylase in Cerebral Cortex is Reduced by Phospholipase A2 Inhibition. Gardiner IM, Patel NK, Li A, de Belleroche J., Life Sciences. 1992; Vol 51: pp. PL Acute Compartment Syndrome Following Ankle Fracture Dislocation Ashworth MA, Patel N, Journal of Orthopaedic Trauma. 1998; 12(1): Basic Surgical Training FRCS to MRCS: A Transition Period Patel NK, Bhinda H, College and Faculty Bulletin, Annal of the Royal College of Surgeons. 1998; 80(2): Incidental Finding of Trigeminal Neuronal Hamartoma at Surgery for Microvascular Decompression for Tic 8

9 Patel NK, Moss T, Coakham HB Journal of Neurosurgery. 2000; 93(3): Subthalamotomy for Parkinson s Disease (Chapter) Gill SS, Patel NK, Heywood P In Tarsy D, Vitek J, Lozano A, editors. Surgical Treatment of Parkinson s Disease and Other Movement Disorders. Humana, MRI-Directed Subthalamic Nucleus Surgery for Parkinson s Disease Patel NK, Heywood P, O Sullivan K, Love S, Gill SS Stereotactic and Functional Neurosurgery. 2002; 78(3-4): Unilateral Lesioning of the Subthalamic Nucleus in Parkinson s Disease Patel NK, Heywood P, O Sullivan K, Love S, Gill SS Brain. 2003; 126: How accurate is MRI in predicting neurovascular compression in patients with Trigeminal Neuralgia? Patel NK, Aquilina K, Clarke Y, Renowden SE, Coakham HB British Journal of Neurosurgery. 2003; 17(1): Implantation of deep brain stimulation electrodes in unshaven patients. Plaha P, Patel NK, Gill SS Journal of Neurosurgery. 2003; 99(1): MRI-directed Bilateral Stimulation of the Subthalamic Nucleus in Patients with Parkinson s Disease. Patel NK, Plaha P, O Sullivan K, McCarter R, Heywood P, Gill SS Journal of Neurology, Neurosurgery and Psychiatry. 2003; 74(12): Subthalamic region stimulation for Essential Tremor. Plaha P, Patel NK, Gill SS Journal of Neurosurgery. 2004;101(1): Current and Future Surgical Therapies for PD (Chapter) Patel NK, Gill SS Birmingham Movement Disorders Course Manual. 2004: Foreign accent following head injury and stroke: syndrome or epiphenomenon? Edwards RJ, Patel NK, Pople IK European Journal of Neurology. 2005; 53(2): An Implantable Guide Tube for MRI-directed Functional Neurosurgery (Chapter). Patel NK, Plaha P, Gill SS Accepted for publication in Starr P, Barbaro N, Larson P, editors. Neurosurgical Operative Atlas 2E: Functional Neurosurgery. Thieme, Some patients with multiple sclerosis have neurovascular compression causing their trigeminal neuralgia and can be treated effectively with MVD: Report of five cases. 9

10 Athanasiou TC, Patel NK, Clarke Y, Varian E, Renowden SE, Coakham HB British Journal of Neurosurgery. 2005; 19(6): A Multicenter, Randomized, Double-Blind, Placebo-Controlled Trial of Liatermin (r-methugdnf) Administered by Bilateral Intraputaminal Infusion to Patients With Idiopathic Parkinson s Disease. Lang AE, Gill S, Patel NK, Lozano A, Nutt JG, Penn R, Brooks DJ, Hotton G, Moro E, Heywood P, Brodsky MA, Burchiel K, Hutchinson M, Kelly P, Dalvi A, Scott B, Stacy M, Turner D, Wooten V GF, Elias WJ, Laws ER, Dhawan V, Stoessl AJ, Matcham J, Coffey RJ, Traub M (Member of Publication Committee) Annals of Neurology. 2006; 59(3): Stimulation of the caudal zona incerta is superior to stimulation of the subthalamic nucleus in improving contralateral parkinsonism. Plaha P, Ben-Shlomo Y, Patel NK, Gill SS. Brain. 2006;129(7): Trigeminal neuralgia (Chapter) Love S, Patel NK New Encyclopaedia of Neuroscience 19. Trigeminal neuralgia and its Management (Review) Bennetto L, Patel NK, Fuller G British Medical Journal. 2007;334: Magnetic resonance imaging-directed method for functional neurosurgery using implantable guide tubes Patel NK, Plaha P, Gill SS Neurosurgery. 2007;61(5 Suppl 2): Comparison of atlas- and magnetic resonance imaging-based stereotactic targeting of the subthalamic nucleus in the surgical treatment of Parkinson s disease Patel NK, Gill SS Accepted for publication in Stereotactic and Functional Neurosurgery 22. Neurosurgical Techniques in Chronic Pain Patel NK Requested for publication in Brook, Connell and Pickering, editors. Oxford Handbook of Pain Management, Oxford Medical Publications 23. Ablative Therapies in Chronic Pain Management (Chapter) Stannard CF, Patel NK Requested for publication in Oxford Textbook of Palliative Medicine, 4 th Edition 10

11 E. Abstracts Published 1. Induction of Ornithine Decarboxylase in Cerebral Cortex is Reduced by Phospholipase A2 Inhibition. Gardiner IM, Patel NK, Li A, de Belleroche J, Neuroscience letters. 1992; 42: p.s37 2. The Foreign Accent Syndrome: A Rare Sequela of Head Injury and Stroke Edwards RJ, Patel NK, Pople IK, Journal of Neurological Sciences, 2001; 187: p.s Unilateral Lesioning of the Subthalamic Nucleus in Parkinson s Disease Patel NK, O Sullivan K, Heywood PH, Gill SS, Journal of Neurological Sciences, 2001; 187: p.s MRI-Directed Method for Subthalamic Nucleus Targeting for the Treatment of Parkinson s Disease. Patel NK, O Sullivan K, Heywood P, Gill SS. Proceedings of 12 th World Congress of Neurosurgery, Unilateral Subthalamotomy in Advanced Parkinson s Disease. Patel NK, O Sullivan K, Heywood P, Gill SS. Proceedings of 12 th World Congress of Neurosurgery, Bilateral Pallidal Stimulators for Hyperkinetic Movement Disorder in an 11-year-old: A Case Report. Gill SS, Curran A, Tripp J, Melikas L, Hurran C, Stanley O, Stephenson E, Patel NK. Proceedings of 12 th World Congress of Neurosurgery, Intraparenchymal Putaminal Administration of Glial-Derived Neurotrophic Factor in the Treatment of Advanced Parkinson s Disease Gill SS, Patel NK, O Sullivan K, Brooks DJ, Hotton GR, Svendsen C, Heywood P Neurology, 2002; 58(7): p.a Chronic Intraputaminal Infusion of Glial Derived Neurotrophic Factor (GDNF) in the Treatment of Advanced Parkinson s Disease Patel NK, Heywood P, Hotton GR, Brooks DJ, Svendsen CN, Gill SS Movement Disorders, 2002; 17 (Suppl. 5): P Chronic Intraputaminal Infusion of Glial Derived Neurotrophic Factor (GDNF) in the Treatment of Advanced Parkinson s Disease: An 18F-dopa PET study Hotton GR, Gill SS, Patel NK, Heywood P, Svendsen CN, Brooks DJ 11

12 Movement Disorders, 2002; 17 (Suppl. 5): P Implantable Guide Tubes allow Functional Neurosurgery to be performed under General Anaesthesia. Patel NK, Gill SS Movement Disorders, 2002; 17 (Suppl. 5): P Chronic Intraputaminal Infusion of Glial Derived Neurotrophic Factor (GDNF) in the Treatment of Advanced Parkinson s Disease Patel NK, Heywood P, Hotton GR, Brooks DJ, Svendsen CN, Gill SS Journal of Neurosurgery, 2003; 12. Subthalamic region stimulation for Essential Tremor Plaha P, Patel NK, Gill SS. Journal of Neurosurgery, The long-term effect of Glial Derived Neurotrophic Factor infusions on 18 F-dopa uptake in PD. Hotton GR, Patel NK, Gill SS, Heywood P, Svendson CN, Brooks DJ. Neurology The zona incerta may be a better target than the subthalamic nucleus for deep brain stimulation for Parkinson s disease. Plaha P, Shlomo YB, Patel NK, O Brien D, O Sullivan K, Gill SS. Movement Disorders, 2004; 19, Suppl. 9: S Intraputamenal infusion of glial cell line-derived neurotrophic factor in Parkinson s disease: A two year clinical, cognitive and quality of life outcome study Patel NK, Hotton GR, Plaha P, Bunnage M, Brooks DJ, Svendsen CN, Heywood P, Gill SS. Movement Disorders, 2004; 19 (Suppl. 9): S Intraputamenal infusion of glial cell line-derived neurotrophic factor in Parkinson s disease: Towards a potential neuroprotective and neurorestorative therapy. Patel NK, Hotton GR, Plaha P, Bunnage M, Brooks DJ, Svendsen CN, Heywood P, Gill SS. Acta Neurochirurgica, 2004;146 (8): Intraputamenal infusion of glial cell line-derived neurotrophic factor in Parkinson s disease: A two year clinical, cognitive and quality of life outcome study Patel NK, Bunnage M, Heywood P, Plaha P, Hotton GR, Brooks DJ, Svendsen CN, Gill SS. International Journal of Neuroprotection and Neuroregeneration, 2004; 1(1) 18. Microsurgical treatment of Trigeminal Neuralgia. Long-term follow-up of surgical results and patient satisfaction. Coakham H, Plaha P, Patel NK, Clarke Y, Zakrzewska J. British Journal of Neurosurgery, Bilateral intraputaminal infusion of Liatermin (Glial Cell Line-derived Neurotrophic Factor; r-methugdnf) in subjects with advanced Parkinson s disease. Lang A, Lozano AM, Gill S, Heywood P, Moro E, Penn R, Dalvi A, Burchiel KJ, Nutt J, Kelly P, Hutchinson M, Elias WJ, Wooten F, Turner D, Scott B, Patel NK, Laws ER, 12

13 Matcham J, Coffey R, Traub M. Annals of Neurology, Bilateral intraputaminal infusion of Liatermin (Glial Cell Line-derived Neurotrophic Factor; r-methugdnf) in subjects with advanced Parkinson s disease. Gill S, Heywood P, Lozano AM, Lang A, Moro E, Penn R, Dalvi A, Burchiel KJ, Nutt J, Kelly P, Hutchinson M, Elias WJ, Wooten F, Turner D, Scott B, Patel NK, Laws ER, Matcham J, Coffey R, Traub M. Neurosurgery, Bilateral High Frequency stimulation of the Caudal Zona Incerta for Parkinson s disease: Better Clinical outcome than Subthalamic nucleus stimulation. Plaha P, Ben- Shlomo Y, Patel NK, Gill SS. Journal of Neurosurgery, A unilateral, randomised, double-blind, placebo-controlled trial of GDNF infusion in patients with Parkinson s disease who have already received bilateral chronic GDNF infusion over 2 years. Plaha P, Patel NK, Hotton G, Brooks DJ, Deidre O Brien, Heywood P, Gill SS. Journal of Neurosurgery, Should we stimulate the subthalamic nucleus or the Caudal Zona Incerta in the treatment of idiopathic Parkinson s disease? Plaha P, Ben-Shlomo Y, Patel NK, Gill SS. Stereotactic and Functional Neurosurgery, A unilateral, randomised, double-blind, placebo-controlled trial of Intraputaminal GDNF infusion in patients with Idiopathic Parkinson s disease. Plaha P, Patel NK, Hotton G, Brooks DJ, Deidre O Brien, Heywood P, Gill SS. Stereotactic and Functional Neurosurgery, Bilateral high frequency stimulation of the Caudal Zona Incerta for the treatment of Parkinsonian and Non-Parkinsonian tremor. Plaha P, Patel NK, Gill SS. Stereotactic and Functional Neurosurgery, The Subthalamic nucleus or the Caudal Zona Incerta? Which is a better target for deep brain stimulation in the treatment of Parkinson s disease? Plaha P, Ben-Shlomo Y, Patel NK, Gill SS. Proceedings of 13 th World Congress of Neurosurgery, Bilateral high frequency stimulation of the Caudal Zona Incerta for the treatment of tremor-dominant Parkinson s disease. Plaha P, Patel NK, Gill SS. Proceedings of 13 th World Congress of Neurosurgery, 2005 F. Presentation to National and International Meetings related to M.D. Thesis 1. Hunterian Lecture: GDNF for Parkinson s disease A Potential Restorative Therapy. Patel NK. Society of British Neurological Surgeons Meeting, Edinburgh,

14 2. Chronic Intraputaminal infusion of GDNF in the treatment of Advanced Pakinson s disease. Patel NK, Hotton GR, O Sullivan K, Brooks DJ, Svendsen CN, Heywood P, Gill SS. Oral Presentation. San Diego Phillip C. Gildenberg Resident Award Presentation. 3. A unilateral, randomised, double-blind, placebo-controlled trial of Intraputaminal GDNF infusion in patients with Idiopathic PD. Plaha P, Patel NK, Hotton G, Brooks DJ, Deidre O Brien, Heywood P, Gill SS. World Society for Stereotactic and Functional Neurosurgery, Rome, A unilateral, randomised, double-blind, placebo-controlled trial of GDNF infusion in patients with Parkinson s disease who have already received bilateral chronic GDNF infusion over 2 years. Plaha P, Patel NK, Hotton G, Brooks DJ, Deidre O Brien, Heywood P, Gill SS. American Association of Neurosurgeons, New Orleans, Intraputamenal infusion of glial cell line-derived neurotrophic factor in Parkinson s disease: A two year clinical, cognitive and quality of life outcome study Patel NK, Hotton GR, Plaha P, Bunnage M, Brooks DJ, Svendsen CN, Heywood P, Gill SS. Poster Presentation. International Congress for Parkinson s Disease and Movement Disorders, Rome, Biodelivery of GDNF for neurorestoration and neuroprotection. Workshop on Neurotransplantation and Neuroprotection for Parkinson s disease". Patel NK, XVIth congress of the European society for stereotactic and functional neurosurgery, Vienna, Intraputamenal infusion of glial cell line-derived neurotrophic factor in Parkinson s disease: A two year clinical, cognitive and quality of life outcome study Patel NK, Bunnage M, Heywood P, Plaha P, Hotton GR, Brooks DJ, Svendsen CN, Gill SS. Poster Presentation. The Global College of Neuroprotection and Neuroregeneration Annual Conference, Zermatt The long-term effect of Glial Derived Neurotrophic Factor infusions on 18 F-dopa uptake in Parkinson's disease Hotton GR, Patel NK, Gill SS, Heywood P, Svendson CN, Brooks DJ. Oral Presentation. American Association of Neurology, San Francisco, A pilot study to assess the safety and efficacy of Intraputaminal GDNF Infusion in patients with Parkinson s disease. Gill SS, Patel NK, O Sullivan K, Hotton GR, Brooks DJ, Svendsen CN, Heywood P. Oral Presentation. American Academy of Neurology, Denver Chronic Intraputaminal infusion of GDNF in the treatment of Advanced Pakinson s disease. Gill SS, Patel NK, Hotton GR, O Sullivan K, Brooks DJ, Svendsen CN, Heywood P. Poster Presentation. Society for Neurosciences Meeting, Orlando Chronic Intraputaminal infusion of GDNF in the treatment of Advanced Pakinson s disease. Gill SS, Patel NK, Hotton GR, O Sullivan K, Brooks DJ, Svendsen CN, 14

15 Heywood P. Poster Presentation. Movement Disorder Society Meeting, Miami Chronic Intraputaminal Infusion of Glial Derived Neurotrophic Factor (GDNF) in the Treatment of Advanced Parkinson s Disease: An 18F-dopa PET study. Hotton GR, Gill SS, Patel NK, Heywood P, Svendsen CN, Brooks DJ. Poster Presentation. Movement Disorder Society Meeting, Miami A pilot study to assess the safety and efficacy of Intraputaminal GDNF Infusion in patients with Parkinson s disease. Patel NK, Heywood P, O Sullivan K, Hotton GR, Brooks DJ, Svendsen CN, Gill SS. Oral Presentation. South-West Neurosciences Association (SWENA) Meeting Presentation Prize Winner. G. Presentation to National and International Meetings 1. Long-term Follow-up Study of Patients Treated with the Prestige Artificial Cervical Disc at a Single Center. Patel NK, Robertson JT, Metcalf NH, Gill SS. Congress of Neurological Surgeons, San Diego, Image-guided Deep Brain Stimulation of the PAG/PVG for chronic intractable pain. Khan S, Pickering A, Papouchado M, Love-Jones S, Steeds C, Patel NK. Congress of Neurological Surgeons, San Diego, Bilateral High Frequency stimulation of the Caudal Zona Incerta for Parkinson s disease: Better Clinical outcome than Subthalamic nucleus stimulation. Plaha P, Ben- Shlomo Y, Patel NK, Gill SS. American Association of Neurosurgeons, New Orleans, Should we stimulate the subthalamic nucleus or the Caudal Zona Incerta in the treatment of idiopathic Parkinson s disease? Plaha P, Ben-Shlomo Y, Patel NK, Gill SS. World Society for Stereotactic and Functional Neurosurgery, Rome, Bilateral high frequency stimulation of the Caudal Zona Incerta for the treatment of Parkinsonian and Non-Parkinsonian tremor. Plaha P, Patel NK, Gill SS. World Society for Stereotactic and Functional Neurosurgery, Rome, The Subthalamic nucleus or the Caudal Zona Incerta? Which is a better target for deep brain stimulation in the treatment of Parkinson s disease? Plaha P, Ben-Shlomo Y, Patel NK, Gill SS. 13 th World Congress of Neurosurgery, Marrakech, Morocco, Bilateral high frequency stimulation of the Caudal Zona Incerta for the treatment of tremor-dominant Parkinson s disease. Plaha P, Patel NK, Gill SS. 13 th World Congress of Neurosurgery, Marrakech, Morocco, Bilateral intraputaminal infusion of Liatermin (Glial Cell Line-derived Neurotrophic 15

16 Factor; r-methugdnf) in subjects with advanced Parkinson s disease. Lang A, Lozano AM, Gill S, Heywood P, Moro E, Penn R, Dalvi A, Burchiel KJ, Nutt J, Kelly P, Hutchinson M, Elias WJ, Wooten F, Turner D, Scott B, Patel NK, Laws ER, Matcham J, Coffey R, Traub M. Oral Presentation. American Neurological Association, 129 th Annual Meeting, Toronto, Bilateral intraputaminal infusion of Liatermin (Glial Cell Line-derived Neurotrophic Factor; r-methugdnf) in subjects with advanced Parkinson s disease. Gill S, Heywood P, Lozano AM, Lang A, Moro E, Penn R, Dalvi A, Burchiel KJ, Nutt J, Kelly P, Hutchinson M, Elias WJ, Wooten F, Turner D, Scott B, Patel NK, Laws ER, Matcham J, Coffey R, Traub M. Oral Presentation. Congress of Neurological Surgeons, 53 rd Annual Meeting, San Francisco, Subthalamic region stimulation for Essential Tremor Plaha P, Patel NK, Gill SS. Oral Presentation. American Association of Neurosurgeons, Orlando The zona incerta may be a better target than the subthalamic nucleus for deep brain stimulation for Parkinson s disease. Plaha P., Shlomo YB, Patel NK, O Brien D, O Sullivan K, Gill SS. Poster Presentation. International Congress for Parkinson s Disease and Movement Disorders, Rome, Microsurgical treatment of Trigeminal Neuralgia. Long-term follow-up of surgical results and patient satisfaction. Coakham H, Plaha P, Patel NK, Clarke Y, Zakrzewska J. Society of British Neurological Surgeons Meeting, Oxford, Implantable guide tubes allow functional neurosurgery to be performed under general anaesthesia. Patel NK, Gill SS. Poster Presentation. American Association of Neurosurgeons, San Diego Implantable guide tubes allow functional neurosurgery to be performed under general anaesthesia. Patel NK, Gill SS. Poster Presentation. American Association of Neurosurgeons, San Diego Subthalamic region stimulation for Essential Tremor. Plaha P, Patel NK, Gill SS. Oral Presentation. South-West Neurosciences Association (SWENA) Meeting Implantable guide tubes allow functional neurosurgery to be performed under general anaesthesia. Patel NK, Gill SS. Oral Presentation. British Stereotactic and Functional Neurosurgery Group Meeting, Birmingham Implantable guide tubes allow functional neurosurgery to be performed under general anaesthesia. Patel NK, Gill SS. Poster Presentation. Movement Disorder Society Meeting, Miami Bilateral Pallidal Stimulators for Hyperkinetic Movement Disorder in an 11-year-old: A Case Report. Gill SS, Curran A, Tripp J, Melikas L, Hurran C, Stanley O, Stephenson E, Patel NK. Oral and Poster Presentation. 12 th World Congress of Neurosurgery, Sydney

17 19. Unilateral Lesions of the Subthalamic Nucleus in Parkinson s disease. Patel NK, O Sullivan K, Heywood PH, Gill SS. Oral Presentation. XVII World Congress of Neurology, London The Foreign Accent Syndrome. A rare sequelae of head injury and stroke. Edwards RJ, Patel NK, Pople IK. Poster Presentation. XVII World Congress of Neurology, London MRI-Directed Method for Subthalamic Nucleus Targeting for the Treatment of Parkinson s Disease. Patel NK, O Sullivan K, Heywood P, Gill SS. Oral Presentation. 12 th World Congress of Neurosurgery, Sydney Unilateral Subthalamotomy in Advanced Parkinson s Disease. Patel NK, O Sullivan K, Heywood P, Gill SS. Oral Presentation. 12 th World Congress of Neurosurgery, Sydney Trigeminal Neuralgia in patients with Multiple Sclerosis: Strategy for Surgical Treatment. Patel NK, Athanasiou T, Clarke Y, Renowden S, Coakham HB. Oral Presentation. Congress of Neurological Surgeons, San Antonio A prospective study to assess the use of MRA in the diagnosis of neurovascular compression in patients with Trigeminal Neuralgia and Hemifacial Spasm. Comparison with surgical findings. Patel NK, Clarke Y, Renowden S, Coakham HB. Oral Presentation. Congress of Neurological Surgeons, San Antonio Arachnoid Webs An under-recognised cause of syringomyelia. Clinical presentation, radiological diagnosis and outcome of surgery. Edwards RE, Renowden SA, Patel NK, Bolger CM, Gill SS. Poster presentation. Congress of Neurological Surgeons, San Antonio Induction of Ornithine Decarboxylase in Cerebral Cortex is Reduced by Phospholipase A2 Inhibition. Gardiner IM, Patel NK, Li A, de Belleroche J. Oral Poster Presentatation. Brain Research Association Meeting, Nottingham H. Invited Lectures 1. The Joint Pain/Neurosurgery Service. Now and Into the Future. Wessex and Southwest Pain Society Meeting, Bath, An overview of Functional Neurosurgery. Post Fellowship Neuroanasthesia Study Day, Frenchay Hospital, Bristol, Surgical Treatment for Parkinson s disease. 20 th National Neuro-Radiographers Conference, Bristol,

18 4. Neuroprotection for Parkinson s disease: GDNF Therapy. World Society for Stereotactic and Functional Neurosurgery, Rome, Biodelivery of GDNF for neurorestoration and neuroprotection. Workshop on Neurotransplantation and Neuroprotection for Parkinson s disease". XVIth congress of the European society for stereotactic and functional neurosurgery, Vienna, GDNF treatment for advanced Parkinson s disease. Amgen European Marketing Managers Meeting, Rome Surgery for Movement Disorders. Department of Anaesthesia, Frenchay Hospital, Bristol GDNF treatment for advanced Parkinson s disease. Amgen European Marketing Managers Meeting, London Functional Neurosurgery for Movement Disorders. Neurosciences Directorate, University Hospital of Wales, Cardiff Functional Surgery for the Treatment of Parkinson s Disease. Parkinson s Disease Master Class, Grantham, Lincs Advances in Parkinson s Disease. The 7 th Bristol Neurology GP Study Day, Bristol Chronic intraputaminal infusion of GDNF in the treatment of advanced Parkinson s disease A Pilot Study. GDNF Experts Meeting. Amgen Inc. San Francisco A pilot study to assess the safety and efficacy of infusing GDNF into the putamen of patients with Parkinson s disease. Amgen Inc., Los Angeles, California, USA Intraparenchymal infusion of GDNF for Parkinson s disease. University of Kentucky, Lexington, Kentucky, USA The rationale and design of the PDSURG trial. PD MED Collaborators Meeting, Birmingham, Infusion of GDNF into the putamen of patients with Parkinson s disease. Institute of Movement Neuroscience Workshop, Queen s Square, London Chronic intraputaminal infusion of GDNF in the treatment of advanced Parkinson s disease. 13 th NECTAR Meeting, Amsterdam Infusion of GDNF into the putamen to treat Parkinson s disease. 15 th European Congress of Neuropsychiatry, Barcelona Putaminal administration of the neurotrophic factor GDNF in the treatment of Parkinson s disease. 6th PHARMACIA Symposium: Parkinson s disease Evidence for neuroprotection, Copenhagen, Denmark

19 20. Functional Surgery for the Treatment of Dystonia. South-West Dystonia Society, Bristol 2001 OTHER EXPERIENCE Tropical Medicine: Fellow of the Royal Society of Tropical Medicine and Hygiene Medical School Elective (10/93 12/93): o Cairo University, Cairo, EGYPT. Field study on the morbidity of Schistosoma mansoni. Clinical attachment in general and tropical medicine. o Chikwawa District Hospital, MALAWI Clinical attachment in general and tropical medicine Medecins sans Frontieres in Malawi. o Awarded Royal College of Pathologists Elective Bursary Adventure/Expedition Medicine: Camel Trophy and Land Rover International Competitions (Official Medical Staff Member ) o Camel Trophies Mongolia 1997, Patagonia 1998 and Tonga-Samoa 2000 o Land Rover G4 Global Challenges 2003 and 2006 Media: Neurosurgical Advisor to BBC Holby City Productions (2003) 19