Methylation Summit. Inaugural Australian

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1 Inaugural Australian Methylation Summit 12 to 13 August 2017 Australian Events Centre, Melbourne, Victoria Presented by Understanding methylation basics The effects of the environment on methylation Learn from the world leaders Clinically relevant case studies REGISTER TODAY TO SECURE YOUR SPOT PROUDLY SPONSORED BY Major sponsors Bronze sponsors

2 Inaugural Australian Methylation Summit, Melbourne 2017 Invitation Inaugural Australian Methylation Summit Environmental effects on methylation Dear Practitioner, I d like to invite you to the Inaugural Australian Methylation Summit. Over the last 5 years, I ve seen how rewarding its been for me and how life changing it can be for my patients to address methylation issues. Some of you may think this is a complicated issue, but it isn t. This conference will demystify everything you might have thought about methylation. More and more patients are aware of MTHFR and Methylation and they expect practitioners, Dr s and healthcare professionals to understand the issues and be able to address them. I hope you will join me in Melbourne for this inaugural event and I m sure you will leave this Summit with new insights and treatment strategies that you can implement with every patient every day. I look forward to seeing you there. Kind Regards Carolyn Ledowsky Founder MTHFR Support Australia 2 mthfrsupport.com.au/summit

3 Why you should attend If you want to understand MTHFR and methylation and know how to treat your patients, this conference is a must. Everyone has methylation issues because of the environment we live in, so this affects everyone not just people with MTHFR mutations. Regardless of the genetic SNP s, we need to be able to identify what environmental factors can disrupt these pathways and what we can do about it. You will receive simple clinical applications for patients Case studies to put the science and the application together Step by step instructions on how to start, where to start and what tests to do You will be empowered to walk straight out the door on Sunday and apply these concepts and this knowledge on Monday morning Methylation Basics Class NEED A REFRESHER FIRST? We will simplify complex concepts so that you feel empowered. As part of the Summit we invite you to join us on the Friday afternoon as we take you step by step through the biochemistry, conditions and effects of MTHFR and methylation. Learn how this benefits you and your patients. If you would like to attend this additional class the cost will be $65 plus GST. Register Today to secure your spot Presented by mthfrsupport.com.au/summit 3

4 Inaugural Australian Methylation Summit, Melbourne 2017 Speakers Key Note Speaker Dr Debby Hamilton Dr, Author, Physician in Charge of Clinical Research & Physician Education, Researched Nutritionals Dr. Debby Hamilton is a Paediatrician with experience in primary care, integrative medicine, research, speaking and writing. She is board-certified in pediatrics, physician nutrition, and integrative/ holistic medicine (AIHM). Dr. Debby Hamilton founded Holistic Pediatric Consulting in Colorado in Her practice used an integrative focus to treat children with chronic diseases such as Autism and ADHD. By using functional medical testing, she could evaluate the underlying mechanisms involved in chronic diseases such as inflammation, immune deficiencies and mitochondrial dysfunction. After treating many children with chronic disease, she became interested in understanding the risk factors involved in children developing these illnesses. After researching over 600 references, she wrote Preventing Autism & ADHD: Controlling Risk Factors, Before, During & After Pregnancy. Her book led to her collaboration in the writing of The Healthy Child Guide through the Neurological Health Foundation ( Dr Stephanie Seneff Senior Research Scientist MIT Computer Science and Artificial Intelligence Laboratory Dr. Stephanie Seneff is a Senior Research Scientist at MIT. She has a BS degree from MIT in biology and a PhD from MIT in electrical engineering and computer science. She has published over 200 peer-reviewed papers in scientific journals and conference proceedings. Her recent interests have focused on the role of toxic chemicals and micronutrient deficiencies in health and disease, with a special emphasis on the pervasive herbicide, Roundup and the mineral, sulphur. She has authored over two dozen peer-reviewed journal papers over the past few years on these topics, and has delivered numerous slide presentations around the world. Dr Andrew Rostenberg Functional Medicine Expert, Methylation Researcher, Director of Red Mountain Natural Medicine in Boise, ID Dr Andrew Rostenberg has become a leading voice in the emerging field of functional medicine and genetics, raising awareness of how genetic variation impacts our health. In addition to running a busy practice, Dr. Rostenberg has developed cutting-edge protocols using methylation pathways designed to optimise biochemistry, detoxification, digestion, brain function and more. Due to the popularity of his BeyondMTHFR YouTube channel and website, he has attracted patients from all over the world who seek to optimise their genes and change their lives. He has clinical experience treating patients of all ages and walks of life, ranging from elite athletes and children to those suffering from complex digestive, autoimmune and neurological diseases. Carolyn Ledowsky ND, Founder & Director of MTHFR Support Australia Carolyn ledowsky has become the leader in the field of MTHFR and methylation in Australia. She founded MTHFR Support Australia with a goal to raising the awareness of how MTHFR genetic polymorphisms may affect health. This has lead to the existence of the largest MTHFR and methylation clinic in the world. Carolyn and her team of practitioners work with patients from all over the world. MTHFR Support Australia this year, launched its own brand of products dedicated to patients with MTHFR and methylation issues. Carolyn spends much of her time teaching and training practitioners all over Australia and New Zealand on how to address the genes to make a huge difference to patient outcomes. Carolyn has a Bachelor of Herbal Medicine, Bachelor of Naturopathy, Advanced Diploma of Naturopathy and Diploma of Nutrition. She has also studied courses in genetics at Duke University (Genetics and Evolution) and The University of Maryland (Genes and the Human condition from behaviour to biotechnology) in the US. For full conference programme and speaker topics see:

5 Inaugural Australian Methylation Summit, Melbourne 2017 Speaker Topics Dr Debby Hamilton: Methylation and other genetic mutations lead to increased susceptibility to environmental toxins and infections in children with Autism and Down s syndrome. Autism and Down s syndrome are chronic disabling conditions in children. Although many argue about specific causation, the general consensus is that a combination of genetic and environmental risk factors play a role. Multiple methylation mutations exist in children with autism and Down s syndrome and many of these overlap, contributing to children with Down s syndrome being at an increased risk of developing autism. In addition to methylation issues, these children also have problems in their sulfation pathways and with the enzyme PON1 among others. These contribute to an increase risk of developing digestive issues, chronic infections, mitochondrial dysfunction, immune weakness, autoimmune issues and difficulty with environmental toxins secondary to poor detoxification. Dr Stephanie Seneff: Glyphosate disruption of methylation/ transsulfuration pathways as a key factor in chronic diseases. Glyphosate is the active ingredient in the pervasive herbicide, roundup and is a common contaminant in our food supply. It is not adequately monitored due to its perceived minimal toxicity to humans. Stephanie has identified a link between glyphosate and a large number of metabolic disorders, one of which is impairment in the methylation and transsulfuration pathways. Glyphosate has been shown to deplete methionine supplies in plants and to suppress certain enzymes in common gut microbes that incorporate sulphur from sulphite and sulphate. Glyphosate also plausibly disrupts the pathway that supplies methyl groups from glycine. Furthermore, glyphosate can be expected to disrupt the supply of the essential B vitamin, folate, since it is derived from the shikimate pathway which glyphosate suppresses. An awareness of a link between folate deficiency and spina bifida has led to regulatory action in the United States and Australia to require folic acid fortification in wheat-based products. This has not actually solved the problem of folate deficiency and may in fact make things worse, particularly with regard to increasing risk to autism. In addition, multiple mechanisms by which glyphosate disrupts the supply of sulfate to the body lead to an epidemic in sulfate deficiency in our population, which is linked to a long list of debilitating diseases. Earn CPE and CPD points MTHFR Support Australia is seeking CPE and CPD accreditation for this event. Information will be provided before the event. Registration Costs Early Bird Registration $550 plus GST (Expires 30 June 2017) Full Registration $650 plus GST (Registrations received from 1 July 2017) Student Registration $395 plus GST A copy of your student ID must be ed to office@mthfrsupport.com.au Methylation Basics Class $65 plus GST Venue The Australian Event Centre 1 Larkin Boulevard, Essenden Fields, Melbourne VIC 3041 For accommodation details see: Dr Andrew Rostenberg: Genetic Roots of Stress and Anxiety: The Epigenetics of Catecholamine Metabolism. Discover how environmental changes in the gut and endocrine system have profound impacts on our metabolism of neurotransmitters. We know that people with COMT, MAO, MTHFR and related genes are more susceptible to the effects of stress, with elevated rates of depression, anxiety, panic, worry, insomnia, cravings, addictions and more. Learn how gut imbalances and overgrowth of bacteria and yeast can slow down COMT, SULT and other important detoxification pathways. In addition, learn how oestrogen and testosterone influence our catecholamine pathways adding another layer of environmental stress into our unique genetic pathways. Case studies will be presented and protocols will be provided and discussed on how to best support these issues. Carolyn Ledowsky: Genetic Polymorphisms that affect susceptibility to environmental toxins. Individual differences in gene-environment interactions is key to understanding the different level of risk amongst our patients. Even though we are all exposed to pretty much the same environmental toxins, some genetic mutations will compromise detoxification capacity and make the patient more prone to disease. Understand which SNP s are the most important and how we improve the functioning of these genes to improve patient outcomes and prevent disease onset or progression. mthfrsupport.com.au/summit 5

6 Registration Inaugural Australian Methylation Summit 12 to 13 August 2017 The Australian Event Centre, 1 Larkin Boulevard, Essenden Fields, Melbourne Victoria 3041 RSVP Deadlines: Early Bird 30 June 2017, Full and Student 25 July 2017 Enquiries: Lisa Harrison Registration Title (Dr, Mr, Mrs, Miss, Ms) First Name Surname Position Modality Organisation Address Suburb State Post Code Country Phone Dietary Requirements: Please tick Vegetarian Vegan Gluten-free Lactose Free Other Registration includes Entry to all sessions Lunch, morning and afternoon tea Conference notes Exhibition Early Bird Registration $550 plus GST (Total $605) if registered by 30 June. Full Registration $650 plus GST (Total $715) from 1 July. Student Registration $395 plus GST (Total $434.50) must be accompanied by your student ID. Methylation Basics Class $65 plus GST (Total $71.50) Payment Details Registration Form: Mail: MTHFR Support Australia, PO Box 1265, Neutral Bay Junction, 2089 Fax: office@mthfrsupport.com.au or Register online: Registration Fee AUD$ + Methylation Basic Class $65 (if attending) +10% GST = Total: Method of Payment VISA MasterCard Amex Expiry Date Card Number CCV Name on Card Signature Date Terms and Conditions Cancellations can be made in writing to Carolyn Ledowsky cledowsky@mthfrsupport.com.au up to and including 25 July Due to venue requirements, cancellations cannot be accepted after this time. By ticking this box, you agree to the above terms and conditions Signature Date 6 mthfrsupport.com.au/summit

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