WILMER EYE INSTITUTE JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE THE JOHNS HOPKINS HOSPITAL

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1 Neil M. Bressler, MD The James P. Gills Professor of Ophthalmology Chief, Retina Division 600 North Wolfe Street, Maumenee 752-A Baltimore, Maryland Administrative Office: Fax: To Whom It May Concern: Clinical Faculty J. Fernando Arévalo, M.D. Mary Beth Aronow, M.D. Christopher Brady, M.D. Neil M. Bressler, M.D. Susan B. Bressler, M.D. Peter A. Campochiaro, M.D. Daniel Finkelstein, M.D. Peter L. Gehlbach, M.D., Ph.D. Morton F. Goldberg, M.D. James T. Handa, M.D. Catherine B. Meyerle, M.D. Hendrik Scholl, M.D. Adrienne Scott, M.D. Syed Mahmood Shah, M.D. Mandeep Singh, M.D., Ph.D Akrit Sodhi, M.D., Ph.D. Sharon D. Solomon, M.D. Adam Wenick, M.D., Ph.D. Ingrid Zimmer-Galler, M.D. The Johns Hopkins Hospital 600 N. Wolfe Street Maumenee 205 Baltimore, MD phone fax WILMER toll free ( toll free) Bel Air 620 Boulton Street Bel Air, MD phone fax Bethesda 7315 Wisconsin Avenue West Tower, Suite 610 Bethesda, MD phone fax Columbia Charter Drive Suite 205 Columbia, MD phone fax WILMER EYE INSTITUTE JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE THE JOHNS HOPKINS HOSPITAL We would like to offer you the opportunity to support the 35th Annual Current Concepts in Ophthalmology Meeting to be held at the Johns Hopkins University School of Medicine in Baltimore, Maryland, March 11-16, We expect an attendance of approximately 100 physicians. If you would like to exhibit at this activity, an exhibit fee of $2,500 would entitle you to a six-foot table top display. Johns Hopkins University School of Medicine follows all ACCME guidelines for commercial support. Please visit the course website for more details: This Current Concepts course will highlight the recent developments regarding diagnosis as well as medical and surgical therapy of common eye diseases. The participant should get a comprehensive review of the most current concepts in the management of ophthalmology by experts across the breadth of the field. For example, clinical trials and other evidence in the peer-reviewed literature over the past few years have changed the approach to managing cataract including IOL technology and femtosecond laser cataract surgery, corneal disease including dry eye disease, keratoplasty, and collagen cross linking, glaucoma and minimally invasive glaucoma surgical devices, as well as diabetic retinopathy, macular degeneration, and retinal vein occlusions. Furthermore, the role of optical coherence tomography (OCT) and other imaging advances are expanding the understanding of the anatomy of the anterior and posterior segment of the eye. This course will address the ongoing pattern of registrants with repeat requests for demonstrations of the latest surgical techniques and medical therapies, questions regarding practice management issues and clarification of legislative updates. There is a demand for expert education of new techniques and medical therapies as well as the need for elucidation of associated clinical trials, and this course provides extensive coverage of that. We look forward to your consideration and funding of this educational meeting. We believe this activity is a worthwhile educational endeavor that will meet the needs of ophthalmologists by providing information that is current, relevant, and clinically useful to their practices. The Johns Hopkins University is a 501(c)3 non-profit organization and our Tax ID # is All checks for exhibit fees must be payable to the Johns Hopkins University and sent to Collections Center Drive, Chicago, IL along with an Exhibitor Booth Agreement. Please be sure to reference course # so that the monies are deposited in the appropriate account. More information is available on the Exhibitor Booth Agreement. Frederick 87 Thomas Johnson Drive Suite 102 Frederick, MD phone fax Green Spring Station Falls Rd Pavilion 2, Suite 455 Lutherville, MD phone fax Please contact Kathy Case in the CME office at kcase5@jhmi.edu if you are interested in exhibiting at this conference to receive the Exhibitor Booth Agreement and further directions. Sincerely, Neil M. Bressler, MD The James P. Gills Professor of Ophthalmology Johns Hopkins University School of Medicine Chief, Retina Division Wilmer Eye Institute Main Telephone: or toll free WILMER ( ) retina@jhmi.edu 24 hour page:

2 VAIL PROGRAM SUNDAY, MARCH 11, :30 5:30 Early Registration MONDAY, MARCH 12, 2018 Morning Session 6:00-7:00 Registration and Continental Breakfast Meet the Faculty 6:00 11:00 Exhibits Open Practice Management 6:30-6:40 What 25 Years of Working with Ophthalmologists has Taught Us* John Grande, CFP and Traudy Grande, CFP *This Session is not eligible for AMA PRA Category 1 Credit. 6:40-6:55 Washington Legislative Update for Ophthalmology 2018* Nancey McCann *This Session is not eligible for AMA PRA Category 1 Credit. 6:55-7:00 Welcome and Conference Goals Neil Bressler, MD Anterior Segment Chairs: Yassine Daoud, MD and Terry Kim, MD 7:00-7:15 Advances in Cataract Surgery: New Phaco Machines Yassine Daoud, MD 7:15-7:30 Comparison of Commercially Available Femtosecond Lasers Ronald Krueger, MD 7:30-7:45 FLACS in Complicated Cases William Culbertson, MD 7:45-8:00 Same Day Simultaneous Cataract Surgery Richard Kaiser, MD 8:00-9:00 Complex Cataract Case Presentations William Culbertson, MD, Yassine Daoud, MD, Richard Davidson, MD, Albert Jun, MD, PhD, Terry Kim, MD, Ronald Krueger, MD, and Rolando Toyos, MD 9:00-9:15 Intracameral Medications in Cataract Surgery Richard Kaiser, MD 9:15-9:30 Pupil Expansion Devices and Management of Zonule Loss Richard Davidson, MD

3 9:30-9:45 Outcomes of Retained Lens Fragments in Cataract Surgery Terry Kim, MD 9:45-10:00 Management of Post-surgical Cystoid Macular Edema Susan Bressler, MD 10:00-11:00 ORA Seminar Intraocular Abberometry Yassine Daoud, MD Afternoon Session 4:30-5:00 Refreshment Break Meet the Faculty 4:30 8:00 Exhibits Open Refractive Surgery Chairs: William Culbertson, MD and Ronald Krueger, MD 5:00-5:15 Custom Cataract Surgery Rolando Toyos, MD 5:15-5:30 Multifocal and Extended Depth of Focus IOLs Yassine Daoud, MD 5:30-5:45 Management of Astigmatism Richard Davidson, MD 5:45-6:00 Intraoperative Aberrometry for Cataract Surgery Ronald Krueger, MD 6:00-6:15 Corneal Inlays: What s Approved and What s on the Horizon Christina Prescott, MD, PhD 6:15-6:30 ICL and Bioptics Richard Davidson, MD 6:30-6:45 Topography Guided Ablation Ronald Krueger, MD 6:45-7:00 Starting SMILE Natalie Afshari, MD, FACS 7:00-8:00 Welcome Reception

4 TUESDAY, MARCH 13, 2018 Morning Session 6:30 7:00 Continental Breakfast Meet the Faculty 6:30 11:15 Exhibits Open Practice Management 6:30-6:45 Is Giving Up Some of Your Upside Potential Worth Hedging Part of the Downside Risk?* John Grande, CFP and Traudy Grande, CFP *This session is not eligible for AMA PRA Category 1 Credit. 6:45-7:00 ASCRS Update* Nancey McCann *This session is not eligible for AMA PRA Category 1 Credit. Cornea (Refractive) Chairs: Kathryn Colby, MD, PhD and Mark Terry, MD 7:00-7:15 Social Media for Ophthalmologists Rolando Toyos, MD 7:15-7:30 SMILE versus LASIK Terry Kim, MD 7:30-7:45 Use of Fibrin Adhesives for Epithelial Ingrowth Management Terry Kim, MD 7:45-8:00 Amniotic Membrane Transfer for SJS and TENS Darren Gregory, MD Cornea (Surgical) Chairs: Kathryn Colby, MD, PhD and Mark Terry, MD 8:00-8:15 Descemet s Stripping Without Keratoplasty Kathryn Colby, MD, PhD 8:15-8:30 Starting DMEK Mark Terry, MD 8:30-8:45 DMEK Complications Mark Terry, MD 8:45-9:00 When to Perform DSAEK versus DMEK Mark Terry, MD 9:00-9:15 Trends in Corneal Transplantation Natalie Afshari, MD, FACS 9:15-9:30 Intraoperative OCT for Corneal Surgery William Culbertson, MD

5 9:30-9:45 DALK for Keratoconus Samar Al-Swailem, MD 9:45-10:00 Keratoprosthesis: How Has Technology Changed? Kathryn Colby, MD, PhD 10:00-10:15 Endothelial Graft Inserters Mark Terry, MD 10:15-11:15 Endothelial Keratoplasty Graft (DMEK) Inserters Seminar Yassine Daoud, MD Afternoon Session 4:00-4:30 Refreshment Break Meet the Faculty 4:00 7:00 Exhibits Open Practice Management 4:30-5:00 The Confidence of a Life Well Planned* John Grande, CFP and Traudy Grande, CFP *This Session is not eligible for AMA PRA Category 1 Credit. Cornea (Medical) Chairs: Marguerite McDonald, MD, FACS and Christina Prescott, MD, PhD 5:00-5:15 Dry Eye with Stem Cell Deficiency: What are the Options? Christina Prescott, MD, PhD 5:15-5:30 Diagnostics and Therapeutics for Dry Eye Marguerite McDonald, MD, FACS 5:30-5:45 Dry Eye Masqueraders Richard Davidson, MD 5:45-6:00 Management of Dry Eye in Surgical Patients Marguerite McDonald, MD, FACS 6:00-6:15 Updates in Ocular Allergy Michael Raizman, MD 6:15-6:30 Refractive Changes with Cross Linking Michael Raizman, MD 6:30-6:45 Long Term Effects of Cross Linking Samar Al-Swailem, MD 6:45-7:00 How to Evaluate Keratoconus Progression and Cross Linking Success Stephen Klyce, PhD, FARVO

6 WEDNESDAY, MARCH 14, 2018 Morning Session 6:30-7:00 Continental Breakfast Meet the Faculty 6:30 10:35 Exhibits Open Practice Management 6:40-7:00 Smart Strategies for Claiming Social Security Benefits* John Grande, CFP and Traudy Grande, CFP *Practice Management Session is not eligible for AMA PRA Category 1 Credit. Glaucoma Chair: E. Randy Craven, MD 7:00 7:10 Laser Updates Leonard Seibold, MD 7:10 7:20 New Glaucoma Medications Releases Jeffrey Soohoo, MD 7:20 7:30 Managing Perimetry in the EHR Era E. Randy Craven, MD 7:30 7:40 Issues with IOP Leonard Seibold, MD 7:40 7:50 Ab-Interno Prodedures Jeffrey Soohoo, MD 7:50 8:00 Questions and Answers 8:00 8:10 How to Pick the Right MIGS E. Randy Craven, MD 8:10 8:20 Trabeculectomy Steven Gedde, MD 8:20 8:30 Deep Sclerectomy E. Randy Craven, MD 8:30 8:40 Secondary Glaucomas Steven Gedde, MD 8:40 8:50 Pseudoexfoliation Syndrome Leonard Seibold, MD 8:50 9:00 Questions and Answers 9:00 9:10 When to NOT Operate Steven Gedde, MD

7 9:10 9:20 Medicolegal issues with Glaucoma Care E. Randy Craven, MD 9:20 9:30 Cataract Surgery in Glaucoma Patients Jeffrey Soohoo, MD 9:30 9:40 Valve Update Steven Gedde, MD 9:40 9:50 Difficult Cases Leonard Seibold, MD and Jeffrey Soohoo, MD 9:50 10:00 Questions and Answers 10:00 10:35 MIGS Seminar E. Randy Craven, MD, Steven Gedde, MD, Leonard Seibold, MD, and Jeffrey Soohoo, MD Afternoon Session 3:50-4:20 Refreshment Break Meet the Faculty 3:50 7:00 Exhibits Open Retina Chairs: Susan Bressler, MD and Akrit Sodhi, MD, PhD 4:20-4:40 Teleretinal Screening for Macular Disease Christina Weng, MD 4:40-5:00 Initial Treatment of Diabetic Macular Edema: Why Anti-VEGF Instead of Laser or Corticosteroids? How Many Initial Doses? Susan Bressler, MD 5:00-5:20 What to Do about Persistent Diabetic Macular Edema: Laser? Corticosteroids? Other? Neil Bressler, MD 5:20-5:40 Common Questions on Intravitreous Injections: (1) Role of Pre- or Post-Injection Topical Antibiotics (2) Impact of Injections on IOP (3) Impact of Vitrectomy Prior to Injections Anat Loewenstein, MD, MHA 5:40-6:00 Update on Management of Choroidal Neovascularization in Age-related Macular Degeneration Susan Bressler, MD 6:00-6:20 Proliferative Diabetic Retinopathy: Panretinal Photocoagulation (PRP) or Anti-VEGF Agents or Both Neil Bressler, MD

8 6:20-6:40 Managing the Intermediate Stage of AMD: (1) Dietary Supplements (2) Home Monitoring Anat Loewenstein, MD, MHA 6:40-7:00 Questions and Answers

9 THURSDAY, MARCH 15, 2018 Morning Session 7:00-7:30 Continental Breakfast Meet the Faculty 7:00 11:30 Exhibits Open Surgical Retina for the Comprehensive Ophthalmologist Chairs: J. Fernando Arevalo, MD, FACS and Anat Loewenstein, MD, MHA 7:30-7:45 Pseudoholes, Lamellar Holes, Epiretinal Membranes What s the Difference? Scott Oliver, MD 7:45-8:00 What s New in Uveal Melanoma? Scott Oliver, MD 8:10-8:30 Endophthalmitis After Cataract Surgery in 2018 Christina Weng, MD 8:30-8:50 Heads-Up Displays Possible Future of Retina Surgery Anat Loewenstein, MD, MHA 8:50-9:10 3D Visualization Systems J. Fernando Arevalo, MD, FACS 9:10-9:30 Macular Hole Surgery: What s the Latest? J. Fernando Arevalo, MD, FACS 9:30-9:50 Vitreomacular Traction: What Do We Know about Ocriplasmin? Christina Weng, MD 9:50-10:10 Managing Macular Edema When an ERM is Present Anat Loewenstein, MD, MHA 10:10-10:30 The Lens Went South: What Should the Cataract Surgeon Do? Christina Weng, MD 10:30-11:30 Retina OCT Seminar (or 3D Surgical Seminar) J. Fernando Arevalo, MD and Christina Weng, MD Afternoon Session 4:00-4:30 Refreshment Break Meet the Faculty 4:30 7:00 Exhibits Open Practice Management 4:00-4:30 Washington Legislative Update for Ophthalmology 2018* Nancey McCann *This session is not eligible for AMA PRA Category 1 Credit.

10 Anterior Segment and Uveitis Chairs: Susan Lightman, MBBS, PhD and Michael Raizman, MD 4:30-4:45 New Regional Therapies for the Uveitides Susan Lightman, MBBS, PhD 4:45-5:00 Diagnosis of Posterior Uveitides Douglas Jabs, MD, MBA 5:00-5:15 Uveitis: What s the Work-Up? Susan Lightman, MBBS, PhD 5:15-5:30 Questions and Answers 5:30-5:45 Acute Retinal Necrosis Can We Use Oral Valcyclovir Rather Than Oral Acyclovir? Susan Lightman, MBBS, PhD 5:45-6:00 Dry Eye Diagnostic Testing Michael Raizman, MD 6:00-6:15 Questions and Answers 6:15-6:30 Anti-Inflammatory Therapy of the Non-infectious Posterior Uveitides Douglas Jabs, MD, MBA 6:30-6:45 Treatment Options for Keratoconus: Crosslinking and Beyond Michael Raizman, MD 6:45-7:00 Questions and Answers

11 FRIDAY, MARCH 17, 2018 Morning Session 7:00-7:30 Continental Breakfast Meet the Faculty 7:00 10:00 Exhibits Open Uveitis Chairs: Douglas Jabs, MD, MBA and Susan Lightman, MBBS, PhD 7:00-7:20 The MUST Trial: 7-Year Results Douglas Jabs, MD, MBA 7:20-7:40 Other Biologics for the Uveitides Susan Lightman, MBBS, PhD 7:40-8:00 Anti-TNF-α Monoclonal Antibody Therapy for the Uveitides Douglas Jabs, MD, MBA 8:00-8:20 Toxoplasmic Retinochoroiditis Susan Lightman, MBBS, PhD 8:20-8:40 Uveitic Macular Edema Douglas Jabs, MD, MBA 8:40 9:00 Questions and Answers Oculoplastics and Orbit Chair: Sophie Liao, MD 9:15 9:30 Update on Non-Ablative Laser Applications Sophie Liao, MD 9:30 9:45 Orbital Tumor Update Sophie Liao, MD 9:45-10:00 Questions and Answers 10:00 Adjourn You will receive an notification to complete the evaluation form and to attest to the number of hours in attendance. The registration desk will remain open during conference hours. The Johns Hopkins University School of Medicine takes responsibility for the content, quality and scientific integrity of this CME activity. This schedule is subject to change.

12 Today s Date: EXHIBIT BOOTH AGREEMENT The Wilmer Eye Institute's 35 th Annual Current Concepts in Ophthalmology Vail Marriott, Vail, Colorado March 11-16, 2018 * COMPANY: CONTACT NAME: ADDRESS: CITY: STATE: ZIP: PHONE: FAX: DISPLAY FEE: $2,500 NAME AND OF REPRESENTATIVES TO BE PRESENT AT CONFERENCE: REP 1: REP 1 REP 2: REP 2 Exhibitor representatives who would like to attend educational sessions are required to register separately for the conference. Exhibit space includes: One 6'x30" table and 2 chairs will be provided. # Outlets Needed: Exhibits will be held at the Vail Marriott, Vail, Colorado. Access to the exhibit area will be available for set-up on March 11, 2018 beginning at 12:00 p.m. Registration will begin at 3:30 p.m. on Sunday, March 11, 2018 and 6:00 a.m. on Monday, March 12, Due to lack of storage space, please do not ship display to arrive prior to March 8, It is your company s responsibility to make arrangements with a courier service to have the display picked up immediately following the last day of the activity. Shipments should be addressed as follows: Vail Marriott 715 West Lionshead Circle Vail, CO ATTN: Kathy Case PLEASE HOLD FOR THE Current Concepts in Ophthalmology CONFERENCE, held March 11-16, I agree to abide by the ACCME Standards for Commercial Support: Specifically 4.2 states: Product-promotion material or product-specific advertisement of any type is prohibited in or during CME activities. The juxtaposition of editorial and advertising material on the same products or subjects must be avoided. Live (staffed exhibits, presentations) or enduring (printed or electronic advertisements) promotional activities must be kept separate from CME. For live, face-to-face CME, advertisements and promotional materials cannot be displayed or distributed in the educational space immediately before, during, or after a CME activity. Providers cannot allow representatives of Commercial Interests to engage in sales or promotional activities while in the space or place of the CME activity. (Refer to ACCME standards at It is the Johns Hopkins Medicine policy that faculty and staff, employees, students, trainees, and volunteers may not accept gifts or entertainment, regardless of value, from pharmaceutical companies or medical device manufacturers or suppliers with respect to any activity at any JHM member organization site and any activity conducted under the auspices of or using the name of any JHM member organization. This policy extends to all exhibitors of this activity. To adhere to this policy no pens, pads, candy, etc. may be offered at your exhibit table. By signing below the above company acknowledges and agrees to the following (1) The required exhibit fee is for the sole purchase of exhibit space and two complimentary registrations for exhibiting personnel. These personnel must complete and submit a registration form prior to the activity. (2) If more than two personnel wish to attend they must register separately and pay the full registration fee. (3) Payment is required by the company prior to the activity. (4) Each of the costs subsidized by the fee is incremental to the exhibit space and not standard institutional or organizational overhead, and (5) any payment to exhibit is not intended to influence planning of any CE/CME activity or interfere with presentations at any associated CE/CME activity. PRINT OR TYPE NAME AUTHORIZED SIGNATURE DATE CHECK MUST BE MADE PAYABLE TO The Johns Hopkins University/ Johns Hopkins University Federal Tax ID: Kindly return this form with payment upon receipt to Kathy Case, Conference Coordinator, Johns Hopkins University, Office of Continuing Medical Education, Johns Hopkins University Central Lockbox, Bank of America, Collections Center Drive, Chicago, IL Kathy Case PHONE: FAX: kcase5@jhmi.edu Program information will be available at three months prior to activity.

13 INVOICE Invoice Number: Date: The Johns Hopkins University School of Medicine Office of Continuing Medical Education Turner 20, 720 Rutland Avenue Baltimore, MD Phone: Fax: The Wilmer Eye Institute's 35 th Annual Current Concepts in Ophthalmology March 11-16, 2018 * Vail Marriott, Vail, Colorado TO: Company Name: FOR: Exhibit Fee AMOUNT: $ 2,500 DUE: Payment is due 5 business days prior to start of activity. The Johns Hopkins University Federal Tax ID: NOTE: Activity budget number on the check. PAYMENT TYPE: [ ]CHECK PAYABLE TO: The Johns Hopkins University/ [ ]Via WIRE TRANSFER TO JOHNS HOPKINS: BANK NAME: Bank of America ACCOUNT NAME: Johns Hopkins University Central Lockbox ACCOUNT NUMBER: ABA NUMBER: REFERENCE: Continuing Medical Education; ; Company Name: [ ]CREDIT CARD: [ ]VISA [ ]MASTERCARD [ ]DISCOVER [ ]AMEX Card # Exp. Date Name on Card Signature and Date MAIL TO: Kathy Case, CME Conference Coordinator The Johns Hopkins University School of Medicine Office of Continuing Medical Education Johns Hopkins University Central Lockbox Bank of America Collections Center Drive Chicago, IL 60693

14 Form W-9 Request for Taxpayer Give Form to t he (Rev. December 2014) requester. Do not Identification Number and Certification Department of the Treasury Internal Revenue Service ~ Q) Ol 1 Name (as shown on your income tax return). Name is required on this line; do not leave this line blank. Johns Hopkins University 2 Business name/disregarded entity name, if different from above send to the IRS. J HU School of Medicine "' a. c: 3 Check appropriate box for federal tax classification; check only one of the following seven boxes: 4 Exemptions (codes apply only to 0 certain entities, not individuals; see D lndividuavsole proprietor or D C Corporation D S Corporation D Partnership D TrusVestate instructions on page 3): Q) "' single-member LLC c. 5 Exempt payee code (if any) ~.-::: D Limited liability company. Enter the tax classification (C=C corporation, S=S corporation, P=partnership)., Note. 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