Physiology. Offered in the School of Medical Sciences. Basic Human Physiology

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1 Physiology Offered in the School of Medical Sciences Basic Human Physiology HPHS111 W1 (52L-4T-33P-0S-42H-21R-0F-0G-8A-15W-16C) Aim: The student must demonstrate an understanding of the structure and function of the various organ systems in the human body including their role in maintaining homeostasis Content: Introduction to basic and physical and chemical concepts; Introduction to cells, tissues, homeostatic control mechanisms, nutrition, blood, metabolism and the basic structure and function of the nervous, cardio vascular, respiratory, renal, gastro intestinal, endocrine and reproductive systems. Practical: 1x 3hrs weekly. Lectures: 5 x 45 min lectures weekly Assessment: Class assessment makes up 40% of the final mark (generated from assessment of practical reports, 2 tutorial tests and 2 theory tests); one two -hour written paper examination makes up 60% of final mark. If a student is absent from a test, a medical certificate must be produced immediately on return to enable the student to be re-tested. A zero mark will be otherwise allocated. The make-up test will be in the form of a viva. DP requirement: 90% practical, 100% test attendance. 40% achieved in the semester mark Physiological Changes in Exercise & Training HPHS112 W2 (52L-4T-33P-0S-41H-22R-0F-0G-8A-15W-16C) Aim: An integrated understanding of the role of the cardio respiratory and muscular systems in exercise and training Content: A study of different types of muscles and their role and changes during exercise and training; Nerve cells and their function; The central nervous system; The autonomic nervous system and the special senses with special reference to exercise and training; A study of the heart, the major blood vessels and blood circulation and regulation

2 of cardiovascular function during rest, exercise and training; The components and functions of the digestive system; The metabolic processes; nutrition and training. Environmental aspects of exercise and training. Practicals: Practicals: 1x 3 hrs weekly. Lectures: 5 x 45 min lectures weekly Assessment: Class assessment makes up 40% of the final mark (generated from assessment of practical reports, 2 tutorial tests and 2 theory tests; one two-hour written examination paper makes up 60% of final mark. If a student is absent from a test, a medical certificate must be produced immediately on return to enable the student to be retested. A zero mark will be otherwise allocated. The make-up test will be in the form of a viva. DP requirement: 90% practical, 100% test attendance. 40% obtained for semester mark. Physiology 1 HPHS1NU (52L-0T-0P-0S-102H-0R-0F-0G-6A-15W-16C) Aim: To provide core knowledge on the structure, principles of function and integrated control of neuromuscular, blood and immune systems. To become familiar with the relevant core knowledge of the structure and function of the human gastro intestinal system and blood. To equip students with relevant core knowledge of the structure and function of the cardiovascular and respiratory systems of the human body Content: Homeostasis, Membrane, nerve and muscle physiology. Introduction to the functioning of the nervous system, cardiovascular, respiratory, renal and gastro intestinal systems. Basic concepts of blood and immunology. Endocrine and reproductive physiology. Assessment: Course work assessment: (i) 2 class tests - each test will be 1 hour long and (ii) assignments. Each test will contribute equally to the semester mark. Assignments will contribute 30% to the semester mark and tests will contribute 70% to the semester mark. If a student is absent from a test, a medical certificate must be produced immediately on return to enable the student to be retested. A zero mark will otherwise be allocated. The make-up test will be in the form of a viva.

3 Examination assessment: One two hour written examination. The final module mark will be made up of 40% semester mark and 60% examination mark. DP requirement: DP requirements: 40% obtained for the semester mark Homeostasis HPHS221 W1 (52L-4T-33P-0S-41H-22R-0F-0G-8A-15W-16C) Aim: On completion of this module students should be able to relate how the body maintains homeostasis by use of the relevant bodily systems in health and disease. Students should also attain proficiency in related practicals. Content: Structure and function of the components of the neuromuscular, respiratory, renal and gastro intestinal system; Blood and body fluids, the regulation of extracellular fluid composition and volume and in acid-base balance; Renal, respiratory and gastro intestinal adjustments in health and disease; Metabolism of carbohydrates, proteins and lipids; Thermo regulation by physical and physiological mechanism. Practicals: Practicals: 1 x 3 hrs weekly Lectures: 5 x 45 min lectures weekly Assessment: Course work assessment: 2 x 1hr Theory test & 1 x 1hr practical test and course work practical assignments will constitute 40% of the final module mark. If a student is absent from a test, a medical certificate must be produced immediately on return to enable the student to be retested. A zero mark will otherwise be allocated. The make-up test will be in the form of a viva. Examination assessment: One 2 hr written paper that will constitute 60% of the final module mark DP requirement: 90% practical, 100% test attendance. A minimum of 40% required for the semester mark Integration and Communication HPHS222 W2 (52L-4T-33P-0S-41H-22R-0F-0G-8A-15W-16C) Aim: To study the integrated function of human organ systems in health and disease. Content: A study of the anatomy and function of nerve cells, spinal cord, brain sympathetic and parasympathetic nervous system; a study of the function of the

4 special senses; disorders of the nervous system. The structure of the heart and its function as a pump; the vascular system, blood composition and function of its components; Blood pressure control and hypertension; Cardiovascular homeostasis in health and disease. Structure of the endocrine glands, hormonal secretion and associated abnormalities. Reproduction and hormonal control of sexual functions. Practicals: Practicals: 1 x 3hrs weekly Lectures: 5 x 45 min lectures weekly Assessment: Coursework assessment: 2 x 1 hour theory tests and 1 x 1 hour practical test and coursework practical assignments will constitute 40% of the final module mark. If a student is absent from a test, a medical certificate must be produced immediately on return to enable the student to be retested. A zero mark will otherwise be allocated. The make-up test will be in the form of a viva. Examination assessment: One 2 hr written paper that will constitute 60% of the final module mark DP requirement: 90% practical, 100% test attendance. A minimum of 40% required for the semester mark Foundations of Physiology HPHS231 W2 (52L-12T-78P-10S-140H-20R-0F-0G-8A-15W-32C) Prerequisite Requirement: BIOL103W1 or Biol101W1; CHEM110W1; CHEM120W2; PHY S131W1; BIMI120W2 or BIOL102W2 Aim: To provide core knowledge on the structure, principles of function and integrated control of neuromuscular, gastro intestinal, blood and immune systems Content: Homeostasis and homeostatic mechanisms; Cellular transport systems and chemical messengers; Neuron structure and physiology, signal transduction, intraneuronal and interneuronal signal transformation and transmission; muscle classification, structure, chemistry, physiological roles and mechanisms of contraction; Autonomic nervous system: structure, components, chemistry and physiological roles; Circulating body fluids; Haemostasis; Immune mechanisms in health and disease; Structure, function and regulation of the gastro intestinal system

5 Practicals: Practicals: 2 x 3hrs weekly. Lectures: 5 x 45 min lectures weekly Assessment: Course work assessment: 2 x 1 hour theory tests and 2 x 1 hour practical tests and written assignments per semester will contribute to 40% of final module mark. Examination assessment: One 2 hour written paper will constitute 60% of final module mark. If a student is absent from a test, a medical certificate must be produced immediately on return to enable the student to be retested. A zero mark will be otherwise allocated. The make-up test will be in the form of a viva. DP requirement: 90% practical, 100% test attendance. A minimum of 40% required for the semester mark Cardiorespiratory and Renal Physiology HPHS232 W2 (52L-12T-78P-10S-140H-20R-0F-0G-8A-15W-32C) Prerequisite Requirement: BIOL103W1 or BIOL101W1; CHEM110W1; CHEM120W2; PHY S131W1; BIMI120W2 or BIOL102W2 Aim: To provide core knowledge on the structure, principles of function and integrated control of cardiovascular, respiratory and renal systems. Content: Electrical and mechanical activity of the heart; haemodynamics: the vascular system, microcirculation and lymphatics; the peripheral circulation and circulation through special regions; cardiovascular regulatory mechanisms in health and disease; Structure, function and regulation of the respiratory system. Structure and function of the renal system: Mechanism of urine formation and micturation; Homeostatic role of the kidneys in body-fluid, electrolyte and acid-base regulation, renal function in disease and drug handling. Practicals: Practicals: 2 x 3hrs weekly. Lectures: 5 x 45 min lectures weekly Assessment: Coursework assessment: 2 x 1 hour theory tests and 2 x 1 hour practical tests and assignments per semester will contribute to 40% of final module mark. Examination assessment: One 2 hour written paper will constitute 60% of final module mark. If a student is absent from a test, a medical certificate must be produced immediately on return to enable the student to be retested. A zero mark will be otherwise allocated. The make-up test will be in the form of a viva.

6 DP requirement: 90% practical, 100% test attendance. A minimum of 40% required for the semester mark Physiology 2 HPHS2NU (52L-0T-0P-0S-102H-0R-0F-0G-6A-15W-16C) Aim: To equip students with the knowledge of how to apply Physiology to clinical conditions. To integrate basic introductory physiology concepts with clinical conditions Content: Applied cardiovascular physiology and pathophysiology, including an introduction to cardiac failure and hypertension. Nutritional aspects of physiology related to nursing practice. Applied respiratory physiology and pathophysiology. The Immune system and HIV. Practicals: Practicals: 2 x 3hrs weekly. Lectures: 5 x 45 min lectures weekly Assessment: Coursework assessment: 2 x 1 hour theory tests and 2 x 1 hour practical tests and assignments per semester will contribute to 40% of final module mark. Examination assessment: One 2 hour written paper will constitute 60% of final module mark. If a student is absent from a test, a medical certificate must be produced immediately on return to enable the student to be retested. A zero mark will be otherwise allocated. The make-up test will be in the form of a viva. DP requirement: 40% obtained for the semester mark. Human Genetics Applied Physiology HPHS322 W2 (52L-12T-78P-10S-140H-20R-0F-0G-8A-15W-32C) Prerequisite Requirement: HPHS231W1, HPHS232W2, BIOC201W1, BIOC202W2 Aim: Knowledge and understanding of normal body metabolism and thermoregulation and the adaptive physiological changes that occur during stress due to environment, exercise and disease. Knowledge and understanding of chromosomal basis of heredity, human and population genetics and genetic diseases. Knowledge and understanding of immunological defence mechanisms Content: Metabolism during well-fed, fasting, starving and diseased states;

7 Thermo regulation and the consequences of the breakdown thereof; nutrition, malnutrition and the balanced diet; Environmental factors in health and disease; Stress; Exercise; regulation and interaction of multiple systems; Integrative and adaptive mechanisms of physiological functions in health and disease; Chromosomal basis of heredity and chromosomal disorders; Population genetics; Genetic diseases and their treatment. Practicals: 2 x 3hrs weekly 5 x 45 min lectures weekly Assessment: Coursework assessment: 2 x 1 hour theory tests and 2 x 1 hour practical tests and an assignment per semester will contribute to 40% of final module mark. Examination assessment: One 2 hour written paper will constitute 60% of final module mark. If a student is absent from a test, a medical certificate must be produced immediately on return to enable the student to be retested. A zero mark will be otherwise allocated. The make-up test will be in the form of a viva. DP requirement: 90% practical, 100% test attendance. A minimum of 40% required for the semester mark Neuroendocrine Physiology HPHS331 W1 (52L-12T-78P-10S-140H-20R-0F-0G-8A-15W-32C) Prerequisite Requirement: HPHS231W1, HPHS232W2, BIOC201W1, BIOC202W2 Aim: Demonstrate a knowledge and understanding of the nervous system and its regulatory function, a knowledge and understanding of the endocrine and reproductive systems and their function Content: The peripheral nervous system, The somatosensory system and special senses, Spinal organization of motor function and its control by the cerebral cortex, cerebellum and basal ganglia, Reticular activating system and sleep, The autonomic nervous system and its control, The limbic system, the cerebral cortex and higher functions of the nervous system. General principles of neuroendocrine hormone regulation: synthesis, release, transport, mechanismofaction and regulation of metabolism by the thyroid gland, endocrine pancreas and the adrenal gland. Hormonal control of calcium and phosphate metabolism. Development and function of the male and female

8 reproductive system. Practicals: Practicals: 2 x 3 hrs weekly. Lectures: 5 x 45 min lectures weekly Assessment: Coursework assessment: 2 x 1 hour theory and 2 x 1 hour practical tests and assignments per semester will contribute 40% of the final module mark. Examination assessment: 1 written 2 hour paper will constitute 60% of the final module mark. If a student is absent from a test, a medical certificate must be produced immediately on return to enable the student to be retested. A zero mark will be otherwise allocated. The makeup test will be in the form of a viva DP requirement: A minimum of 40% required for the semester mark. 90% practical attendance and 100% test attendance Specialized Physiological Techniques HPHS701 W1 (15L-15T-100P-0S-30H-0R-0F-0G-0A-15W-16C) Prerequisite Requirement: B.Sc or B.MedSC degree with minimum 60% pass in level 3 Physiology modules. Aim: To demonstrate a knowledge of the theoretical and practical basis of electrolyte, trace element, blood pressure analysis and protein and lipid analysis. Content: Radioisotope techniques; ELISA techniques; Electrolyte, protein and lipid analysis; Haematology and Aggregometry, Atomic Absorption Spectrometry and trace metal analysis; Pharmacophysiological Screening Tests; Animal diet formulation; Histological Techniques Assessment: One 2 hour written paper will constitute the final module mark. DP requirement: 100% practical attendance Ancillary research techn. for Life Sciences HPHS710 (15L-15T-100P-0S-30H-0R-0F-0G-0A-15W-16C) Prerequisite Requirement: B.Sc or B.MedSC degree with minimum 60% pass in level 3 Physiology modules. Aim: To introduce students to general laboratory based Research in Medical Sciences Content: Core aspects of scientific research such as statistics, scientific writing,

9 and the use of different biological models in research. Assessment: Coursework: Practical reports and attendance and 1 x hr statistics test will form 40% final module mark Examination: One 2 hour written paper will constitute 60% of final module mark. DP requirement: minimum of 40% year mark, 90% practical attendance and 100% test attendance Integrative Physiology HPHS711 W1 (20L-40T-0P-0S-78H-20R-0F-0G-2A-15W-16C) Prerequisite Requirement: B.Sc or B.MedSC degree with minimum 60% pass in level 3 Physiology modules. Aim: To provide an advanced integrated study of selected topics in exercise, respiratory and cardiovascular physiology, cytology and neurophysiology Content: Selected essays on exercise, respiratory, cardiovascular physiology, cytology and neurophysiology Assessment: Coursework: Assessment of assignments will form 40% final module mark Examination: One 2 hour written paper will constitute 60% of final module mark. DP requirement: 100% assignment submission. A minimum of 40% for the semester mark Applied Physiology HPHS721 W2 (20L-20T-0P-0S-98H-20R-0F-0G-2A-15W-16C) Prerequisite Requirement: BSc or B.MedSC degree with minimum 60% pass in level 3 Physiology modules Aim: To provide an advanced integrated study in applied aspects of immunology, endocrinology, gastro intestinal, renal and reproductive physiology. It entails a review and presentation on selected topics in Applied physiology. Content: Applied aspects of immunology, endocrinology, gastro intestinal, renal and reproductive physiology

10 Assessment: Coursework : Assessment of written seminar and presentation will form 40 % final module mark Examination: One 2 hour written paper will constitute 60% of final module mark. DP requirement: 100% seminar submission and presentation. A minimum of 40% for the semester mark Pathophysiology HPHS731 W2 (20L-20T-0P-20S-80H-18R-0F-0G-2A-15W-16C) Prerequisite Requirement: BSc or B.MedSC degree with minimum 60% pass in level 3 Physiology modules Content: It entails a review on selected topics in pathophysiology, neuroendocrine control mechanisms, nutrition and metabolism. Assessment: Continuous assessment (class record), 40%; one two-hour written paper, 60% of final mark. DP requirement: 100% assignment submission, A minimum of 40% for the semester mark. A lecture note fee will be charged for this module. Physiology Honours Research Project HPHS741 W2 (20L-60T-220P-60S-100H-20R-0F-0G-0A-26W-48C) Aim: After completion of the module students will be expected to report on results they have obtained during a research project and should be able to critically analyse data and compare their results to known literature in the field Content: Research project in any one of the following Physiology fields: Cardiovascular, Respiratory, Exercise Physiology, Endocrinology, Renal, Environmental or Nutritional/Gastro-intestinal Physiology, Neurophysiology and Immunology. Assessment: Mini dissertation or project write-up (65% of final mark) Research performance during the year (15% of final mark) End of year presentation of results (20% of final mark) DP requirement: As per faculty rules

11 Research Project HPHS811 WY (40L-15T-10P-0S-430H-0R-140F-0G-5A-26W-64C) Aim: To equip the learner with an empirical research experience which will enable him to collect data, statistically analyse and interpret the data and write it up in the form of a mini-thesis which can be seen as a pilot study for a PhD or larger self-initiated project. Content: Literature Review, Research proposal, Ethics application. Methods and Procedures, Results, Discussion & Conclusion. List of References Assessment: Examination of the dissertation. DP requirement: Student s declaration and supervisor s confirmation that mini-thesis is original work of the student and has not been submitted in any form to another university or institution. Research Methodology and Statistics HPHS819 W1 (39L-0T-3P-8S-50H-40R-0F-20G-3A-13W-16C) Aim: To enhance the student s knowledge on research methods. And the tools that are required to analyse the date Content: This module surveys various research methods and prepares the student in the interpretation, presentation and the writing of scientific research reports Assessment: (class mark, 30%), examination: one 3-hour paper (70%). DP requirement: Student must attain a minimum D.P. mark of 50% in order to qualify to write the exams. Muscle Physiology and Metabolism HPHS825 W1 (10L-10T-0P-10S-80H-47R-0F-0G-3A-13W-16C) Aim: To establish in the learner the sound knowledge of the effects of exercise training on skeletal muscle adaptation and function, endocrine system function and metabolic activity in order to understand assessment and intervention strategies. Content: Effects of the different types of exercise and exercise training on

12 skeletal muscle function and adaptation. Bioenergetics applicable to exercise physiology. The effects of exercise and training on endocrine function and maintenance of homeostasis. Neuromuscular physiology Assessment: Assessment of student participation in the module by means of evaluating assignments and presentations shall contribute 40% of the total mark of the module. Formal 3-hour examination shall contribute 60% to the final mark of the module. This examination may be an open and/or closed book examination. DP requirement: Completion of all assignments and assessments Cardiorespiratory Physiology HPHS826 W1 (10L-10T-0P-10S-80H-47R-0F-0G-3A-13W-16C) Aim: To establish in the learner the sound knowledge of those aspects of cardiovascular and respiratory physiology that are needed for an understanding of exercise physiology and the practise of sports medicine. Content: Acute and long term central and peripheral cardiovascular adaptations to exercise. The response of the respiratory system to exercise and training. Cardio respiratory evaluation Assessment: Assessment of student participation in the module by means of evaluating assignments and presentations shall contribute 40% of the total mark of the module. Formal 3-hour examination shall contribute 60% to the final mark of the module. This examination may be an open and/or closed book examination. DP requirement: Completion of all assignments and assessments.