Modesto Junior College Course Outline of Record PHYSO 101

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1 Modesto Junior College Course Outline of Record PHYSO 101 I. OVERVIEW The following information will appear in the catalog PHYSO 101 Introductory Human Physiology 5 Units Prerequisite: Satisfactory completion of BIO 116 or BIO 111 or BIO 101 and ANAT 125 and CHEM 143. Study of body function, organ system integration, communication, and homeostasis at the biochemical, cellular, and system levels. Includes control of osmolarity, protein synthesis and cellular metabolism; cellular communication; neural information processing; blood movement; fluid balance; respiration and digestion; reproduction; sensory perception and control of movement. Intended for students entering the health professions. Field trips are not require (A-F or P/NP - Student choice) Lecture /Lab /Discussion Transfer: (CSU, UC) General Education: (MJC-GE: A ) (CSU-GE: B2, B3 ) (IGETC: 5B ) II. LEARNING CONTEXT Given the following learning context, the student who satisfactorily completes this course should be able to achieve the goals specified in Section III, Desired Learning: A. COURSE CONTENT Required Content: Introduction to Physiology i Organization of the body Homeostasis Chemistry of Life i ii Water and Solutions Biomolecules Elements and Atoms Molecules and Bonds The Cell i ii Plasma Membranes Organelles Cell Junctions Membrane Transport Cell Division Division: Science, Math & Engineering 1 of 10

2 Cell Metabolism i ii Metabolic Reactions Energy Changes in Reactions Glycolysis Krebs citric acid cycle Oxidative Phosphorylation e. Membrane Transport i ii Cellular Membrane Passive Transport Active Transport Epithelial Transport f. Cellular Communication i ii Chemical Messengers Cellular Receptors Signal Transduction g. Nerve Cells i ii Neurons and Glial Cells Membrane Potential Action Potential Synaptic Transmission Neurotransmitters h. Central Nervous System (CNS) i ii Anatomy of CNS Spinal Cord Brain Brain Function Sensory Physiology i ii Receptors and Sensory Pathways Somatic Senses Chemoreception Division: Science, Math & Engineering 2 of 10

3 Hearing and Equilibrium Vision j. Autonomic and Motor Nervous System Autonomic Nervous System Somatic Nervous System k. Endocrine Glands and Hormones i ii Endocrine communication Synthesis of Hormones Secretion and Release of Hormones l. Muscle Physiology i ii Molecular Mechanism of Contradiction Mechanics of Muscle Contraction Types of Skeletal Muscle Fibers Smooth Muscle Cardiac Muscle m. Cardiac Physiology i ii Heart Anatomy Electrical Activity of the Heart Cardiac Cycle Regulation of Cardiac Output n. Blood i ii Plasma and Cellular Elements Red Blood Cells Hemoglobin Clotting o. Blood and Lymphatic Circulation i ii Vascular System Physics of Blood Flow Blood Pressure Regulation of Circulation Capillary Exchange Division: Science, Math & Engineering 3 of 10

4 v Lymphatic System p. Respiration i ii Anatomy of Respiratory System Breathing Mechanism Respiratory Volumes and Air Flows Transport of Gases In the Blood Regulation of Respiration q. Digestive System i ii Functional Anatomy Digestion and Absorption Gastrointestinal Secretion Gastrointestinal; Motility Regulation of Gastrointestinal Function r. Metabolism i ii Energy Balance Regulation of Growth Regulation of Metabolism s. Fluid and electrolyte balance i ii Anatomy of Urinary System Basic Renal Functions Regulation of Fluids and Electrolytes Regulation of ph Micturition t. Reproductive System i ii Gametogenesis Male Reproductive System Female Reproductive System Fertilization and Pregnancy Parturition and Lactation Required Lab Content: Division: Science, Math & Engineering 4 of 10

5 Chemistry i ph Buffers Cellular Transport i Diffusion Osmosis Cell Biology i ii DNA Replication Transcription Translation DNA Fingerprinting e. Neurophysiology Special Senses i ii Vision Hearing Equilibrium Taste f. g. Endocrine Physiology Blood Analysis i ii v Hemotocrit Blood Typing Coagulation Time Differential Blood Counting Hemoglobin h. Cardiovascular Physiology Electrocardiograms Respiratory Physiology Spirometry Division: Science, Math & Engineering 5 of 10

6 j. Renal Physiology i Urinanalysis Renal Function k. Digestion Enzyme Activity l. Metabolism Basal Metabolic Rate m. Muscle Physiology Myogram B. ENROLLMENT RESTRICTIONS Prerequisites Satisfactory completion of BIO 116 or BIO 111 or BIO 101 and ANAT 125 and CHEM 143. Requisite Skills Before entering the course, the student will be able to: e. f. g. h. j. k. l. m. n. o. Apply the principles of dimensional analysis to unit conversions Define subatomic particles, cations, anions and isotopes. Identify atomic number and mass of an element on the periodic table. Calculate molar mass Write balanced chemical equations and identify types of equations. Differentiate between ionic, covalent and polar covalent bonds Describe and identify intermolecular bonding Predict the effect of changing pressure, volume, temperature or number of moles on a gaseous system holding one or more of these variables constant. Define vapor pressure, surface tension and boiling point of substances Calculate mass percent, mass/volume percent and volume percent of a solution. Calculate molarity, molality and osmotic pressure and osmolarity of a solution Differentiate between strong and weak acids; strong and weak bases. Calculate ph and hydrogen ion (H+) concentration Identify oxidized and reduced elements in a single replacement reaction Identify families of organic compounds Division: Science, Math & Engineering 6 of 10

7 p. q. r. s. t. u. w. x. y. a`. a a a a ae. af. ag. ah. a aj. ak. Describe the structure of cells and tissues Compare and contrast the histology and function of the muscle tissues. Identify the external and internal anatomy of the heart Describe the flow of blood through systemic and pulmonary circulations Compare and contrast arteries, arterioles, capillaries, venules and veins Describe the components of the lymphatic system and list their functions. Identify the principal parts of the spinal cord and brain Locate and describe the receptors and structures associated with special senses. Compare and contrast the sympathetic and parasympathetic divisions of the autonomic nervous system. Describe the location, histology, blood and nerve supplies of endocrine glands. Identify the organs of the respiratory system Compare and contrast the functional histology of different regions of respiratory system. Describe the histological structure of the gastrointestinal tract. Identify the organs of the gastrointestinal tract and explain their functions. Describe the external and internal gross and microanatomy of the kidney. Describe the location, structure, histology and function of the sexual organs. Use the language of biology and physiology as it relates to homeostatic mechanisms. Describe the structure and functions of the plasma membrane Describe the structure and functions of the membranous and non-membranous cellular organelles. Explain the role of DNA and gene expression in the control of cellular function. Explain how DNA and RNA control the production of proteins. Explain the role of DNA, RNA and proteins in the functioning of a cell, including cellular communiation, cellular movement,membrane transport and metabolism. C. HOURS AND UNITS 5 Units INST METHOD TERM HOURS UNITS Lect Lab Disc D. METHODS OF INSTRUCTION (TYPICAL) Instructors of the course might conduct the course using the following method: Material relevant to the objectives will be presented through lecture and laboratory exercises. Division: Science, Math & Engineering 7 of 10

8 3. 4. Laboratory instruments, demonstrated by the instructor and used by the students, (including spirometers, electrocardiographs, and computers coupled to data acquisition equipment) are used to investigate physiological principles. Audiovisual materials Hypothetical clinical scenarios to stimulate discussion of physiological concepts. E. ASSIGNMENTS (TYPICAL) EVIDENCE OF APPROPRIATE WORKLOAD FOR COURSE UNITS Time spent on coursework in addition to hours of instruction (lecture hours) Students write weekly laboratory reports. Students write two or three reviews of contemporary research in physiology per term. Students study for exams weekly. Students read textbook chapters weekly. EVIDENCE OF CRITICAL THINKING Assignments require the appropriate level of critical thinking Students will evaluate physiological mechanisms which account for physiological observations. For example: Compare and contrast the role of calcium in the control of cardiac vs. smooth muscle contraction. Students will apply course principles to hypothetical situations to predict physiological responses. For example: Explain how the body compensates for the loss of blood volume. Each student will provide a written assessment of completed lab work and explain the results obtaine F. TEXTS AND OTHER READINGS (TYPICAL) Book: Robert M. Thornton (2004). The Chemistry of Life (2nd /e). Prentice Hall. Book: William J. Germann and Cindy L. Stanfield (2011). Human Physiology (4th/e). Benjamin Cummings. III. DESIRED LEARNING A. COURSE GOAL As a result of satisfactory completion of this course, the student should be prepared to: explain the chemical and physical processes of the human body at the biochemical, cellular, and systemic level as is necessary in the allied health professions. B. STUDENT LEARNING GOALS Mastery of the following learning goals will enable the student to achieve the overall course goal. Required Learning Goals Upon satisfactory completion of this course, the student will be able to: Apply the concept of homeostasis to physiological processes. Explain the importance of biomolecules, water and solutions. Division: Science, Math & Engineering 8 of 10

9 e. f. g. h. j. k. l. m. n. o. p. q. r. s. t. u. w. x. Explain membrane structure and relate it to membrane dynamics. Relate glycolysis, Krebs cycle and oxidative phosphorylation to energy metabolism. Explain the movement of chemicals across the cell membrane and epitheli Compare and contrast different types of receptors and signal transduction mechanisms. Explain the molecular basis for membrane potential, action potential and synaptic transmission. Describe and explain the components of the central nervous system. Discuss higher brain functions including memory, learning and motivation. Diagram sensory pathways associated with somatic sensation, olfaction, vision, hearing and equilibrium. Compare and contrast the major divisions of the autonomic nervous system. Describe the sliding filament theory and the events that occur during excitation-contraction coupling. Compare and contrast the physiology of smooth muscle and skeletal muscle. Describe the conduction system of the heart and phases of the cardiac cycle. Classify the constituents of blood and describe the characteristics of each. Contrast and compare the intrinsic and extrinsic pathways for blood clotting. Relate hydrodynamics to blood circulation and the exchange of material between capillaries and tissues. Describe the mechanics of breathing and the transport of gases in the bloo Relate the anatomy of the renal tubule to the key renal functions of filtration, absorption and secretion. Describe the hormonal and neural control of fluid and electrolyte balance and micturition. Describe the absorption of nutrient molecules and patterns of gastric motility. Explain the hormonal and neural regulation of energy balance in the absorptive and post-absorptive states. Describe hormonal control of energy metabolism, growth and hormone secretion. Discuss the neural and hormonal control of male and female sexual cycles. Lab Learning Goals Upon satisfactory completion of the lab portion of this course, the student will be able to: e. Calculate ph and describe the relation of ph to the conditions of alkalemia and acidemi (Full description of lab learning goals will following when we do the official review.) Compare and contrast diffusion and osmosis. Calculate the osmolarity of chemical solutions. Simulate the processes of transcription and translation resulting in protein synthesis. Imitate using a model of the human eye the conditions of emmetropia, myopia and hyperopi Analyze blood samples to determine coagulation time, hemoglobin value, hematocrit, blood types, differential counts, and total blood counts. Division: Science, Math & Engineering 9 of 10

10 f. g. h. j. k. Record an electrocardiogram (EKG) and analyze the EKG to evaluate the conduction system of the heart. Employ a spirometer to collect lung volumes. Calculate lung capacities. Compare lung volumes and capacities to normal values. Collect urine samples and perform a urinalysis. Experiment with the effects of fluid and salt intake on the rate of urine formation and salt concentration. Analyze the action of specific enzymes on carbohydrates, proteins and fats. Assess the effects of temperature and ph on enzyme activity. Calculate the basal metabolic rate of a mouse based on its oxygen consumption. Analyze endocrine, muscular and neurophysiological function using computer simulations. 3. Recommended Learning Goals Upon satisfactory completion of the course (when the related recommended content is covered) the student will be able to: Explain the role of muscle stretch reflexes in the control of movement. Explain the role of the cerebral cortex and basal nuclei in the control of movement. Explain the role of cells and tissues in specific and non-specific immunity. IV. METHODS OF ASSESSMENT (TYPICAL) A. FORMATIVE ASSESSMENT 3. Quizzes Midterms Lab Reports B. SUMMATIVE ASSESSMENT Comprehensive Final Exam Division: Science, Math & Engineering 10 of 10