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1 Journl of Mentl Helth Reserch in Intellectul Disbilities ISSN: (Print) (Online) Journl homepge: Full Issue PDF, Volume 10, Supplement 1 To cite this rticle: (2017) Full Issue PDF, Volume 10, Supplement 1, Journl of Mentl Helth Reserch in Intellectul Disbilities, 10:sup1, i-222, DOI: / To link to this rticle: Published online: 30 Aug Submit your rticle to this journl Article views: 1270 View relted rticles View Crossmrk dt Full Terms & Conditions of ccess nd use cn be found t Downlod by: [ ] Dte: 31 December 2017, At: 00:30

2 Journl of Mentl Helth Reserch in Intellectul Disbilities CONTENTS Volume 10 Number S An Introduction to the Abstrct Volume of the Luxembourg Congress KEY-NOTE SPEECHES Criticl Fctors to Promote Mentl Helth in ID: Looking for Coherent nd Inclusive Approch Aginst Frgmenttion nd Splitting t Different Orgnistionl Level 4 From Moleculr Studies to Trgeted Tretments in Frgile X Syndrome 6 Chllenging Behviour: Individul Difference Mtters 7 The Disbled Child: The Desire to Know nd Lerning With One s Peers 8 FOCUSED COMMUNICATION Psychotherpy in Supporting People With ID: New Advnces From Reserch nd Clinicl Prctice 9 Mentl Helth nd Qulity of Life in Neurodevelopmentl Disorders 10 Mentl Helth nd Intellectul Disbility: History nd Concepts Towrds Evidence-Bsed Prctices 13 Enlrging the Frme: Issues of Inclusion nd Mentl Helth in n Ageing Society 15 Chllenges of Prtnerships Between Ptients nd Helthcre Professionls 17 Trum nd Trumtic Sequele in People With Intellectul Disbilities 19 Autism nd Offending: Towrds n Evidence-Bsed Approch 22 Coopertion Models Among the Public Helth Sector nd School System: Inclusion of Children With Autism Spectrum Disorder 24 Mentl Helth for People With ID A Chllenge Between Humn Rights nd Scientific Progress 25 Exploring Problem Behviour Exhibited by Children nd Young Adults: Prevlence, Risk Mrkers nd Antecedent Events Associted With Its Occurrence 25 Desinstitution nd Inclusion A Rel Misunderstnding? 27 PRE-CONGRESS COURSES DM-ID-2 Dignostic Mnul Intellectul Disbility: A Textbook of Dignosis of Mentl Disorders in Persons With Intellectul Disbility 29 The Socio-Emotionl Development (SEO) in Dignosis nd Therpy of Adults With Intellectul Disbilities 31 Updte on Psychophrmcology for Persons With Intellectul Disbility And/Or Low Functioning Autism Spectrum Disorder 31 Psychotherpeutic Approches to the Support nd Cre of People With Intellectul Disbilities nd Their Fmilies 33 Dementi in Persons With Intellectul Disbility 33 Assessing Emotionl Development & Emotionl Needs 35 Coching for Front-Line Stff Supporting People With ID nd Chllenging Behviours 36 Reducing Restrints nd Restrictive Behviour Mngement Prctices 37 Lifestyle nd Integrtion of Vulnerble Groups: The Chllenge of Prtnership nd the Trnsmission of Knowledge 38

3 The Institutionl Journey: A Psychonlyticl Point of View with Two Voices 39 ASD nd Chllenging Behviours Cuses nd Prcticl Implictions 40 AGEING AND LIFE-SPAN INDIVIDUAL PAPERS Exploring the Experiences of Dementi in People With n Intellectul Disbility 41 Erly Signs of Dementi in Down Syndrome Bsed on 15-Yer Follow-Up 42 Trnsition to Adulthood Hs Negtive Consequences for Mentl Helth in Individuls With Intellectul Disbilities: Results From Qulittive Interviews nd Secondry Anlyses of Existing Dt 42 Ageing in Willims Syndrome: Longitudinl Trjectories of Neuropsychologicl Functioning in Adults 43 The Erly Presenttion of Dementi in People With Down Syndrome: A Simple Screening Protocol for the Assessment of Dementi in A Smple of the Itlin Popultion 44 Psychomotor Ageing of People With Intellectul Disbility 44 The Identity-Building Process of People With Intellectul Disbility Throughout the Stges of Life 45 Wht Indictes nd Determines Qulity of Life for Elderly People With Intellectul Disbilities? 46 The Germn Aging nd Disbility Study (GADS): Setup nd 5-Yer Follow-Up 46 POSTERS Effects of Aqutic Motor Trining on Blnce, Git nd Fll Risk Among Older Adults With Intellectul Disbilities 47 Dementi in Adults With Down Syndrome: Prevlence, Cuses nd Assessment A Clinicl Approch 47 Stress nd Burden of Stff Working With People With n Intellectul Disbility nd Dementi 48 Cretive Storytelling - Activting Communiction Skills of People With n Intellectul Disbility nd Dementi 49 Interventions for Accompnying nd Supporting People With Intellectul Disbilities nd Dementi First Results of Expert Interviews 50 ASSESSMENT, DIAGNOSIS, AND CLASSIFICATION SYMPOSIA Symposium: Disorders of Intellectul Disbilities nd the ICD Disorders of Intellectul Development s Successors of Mentl Retrdtion nd Intellectul Disbility: Is the Approch of the ICD-11 (drft) n Improvement? 51 Utility of the ICD11 in Dignosing Intellectul Disbility (ID) in LAMICs (Lower nd Middle Income Countries)- An Interntionl Collbortive Study 51 Disorders of Intellectul Development: On the Ongoing Diversity in Europen Terminology Cultures With Respect to People With Intellectul Disbilities 52 INDIVIDUAL PAPERS Wht to do When Interventions Fil? 53 Wht Does Music Revel About Autism? Vlidtion of the Music-Bsed Scle for Autism Dignostics (MUSAD) 53 Development of Germn Version of the Adptive Behvior Assessment System Third Edition (ABAS-3) 54

4 People With Profound Intellectul nd Multiple Disbilities: A Cognitive Skills Profile 55 Vlidtion of the DiBAS-R nd the Impct of Level of Functioning 55 Norming of the Scle of Emotionl Development - Short 56 An Investigtion of the Adpted GAD-7 nd PHQ-9 Clinicl Mesures of Mood for Adults With Intellectul Disbilities 56 Review of Cses Attending Psychitry Service in Lrge Urbn-Bsed Intellectul Disbility Service in Irelnd 57 ABC Awreness-Body-Chrts to Fill in with Colors 58 The Use of Vlidtion in Mentl Helth Nursing for Adults With Intellectul Disbilities nd Mentl Illness: A Descriptive Study 58 Autism Archetype Survey 59 Mood Disorders in Ptients With Intellectul nd Developmentl Disorders: Preliminry Dt on the New Assessment Tool SPAIDD-M 60 Behviourl Equivlents of Psychitric Symptoms in People With Intellectul nd Developmentl Disbilities 61 The SPAIDD-G: New Findings on the Screening Version of the First Psychodignostic Tool for Persons With Intellectul nd Developmentl Disbilities 62 Vlidtion of the SPAIDD-ASD: A New Tool to Assess Autism Spectrum Disorder in Persons With Intellectul Disbility 62 The Assessment of Pin in Persons With NDD With Severe Limittions 63 Dignostic Interview for ADHD in Adults With Intellectul Disbility (DIVA-5-ID) 64 POSTERS The Socil Communiction Questionnire for Adults With Intellectul Disbility 65 Development of n Instrument to Mesure Stress Conditions in Ptients With Intellectul Disbilities nd Psychitric Disorders 66 The Spnish Version of the HoNOS-LD: Preliminry Results on Its Vlidity nd Relibility 67 CASE REPORT OF SERVICE PROVISION SYSTEM SYMPOSIA Symposium: Identify the Key Elements of the Cretion of Inclusive, Inclusive Employment nd Job Retention for People in High Psychologicl Vulnerbility 67 Identify the Key Elements of the Cretion of Inclusive, Inclusive Employment nd Job Retention for People in High Psychologicl Vulnerbility 68 Supporting Self-Determintion for People With Psychitric Disbilities: Fcilittors of Voctionl Recovery nd Subjective Well-Being, the Cse of ATP sbl. - Assocition d ide Pr Trvil Thérpeutique Pour Personnes Psychotiques (Luxembourg) 68 Symposium: How to Enhnce Knowledge Shring nd Appliction Between Acdemi nd Prctice? 69 Brriers nd Fcilittors for the Shring nd Appliction of Knowledge in Cre nd Support for People With Intellectul Disbilities: Results of Systemtic Literture Review 69 First Steps in Mking n Intervention Trnsmissible to Other Cre Providers: From Prctice-Bsed Evidence to Evidence-Bsed Prctice 70

5 Shring Knowledge by Building Networks to Connect Science, Eduction nd Prctice 71 Symposium: Lerning to Look With Generous Eye 71 Enbling Stff to Wtch Ech Client s Personhood in Meningful Wy Using Discovery Awreness (DA) 72 Stepping Bck nd Seeing Differently : Stff Reflections on Ptient Behviour nd the Impct of Discovery Awreness 72 Using Video-Anlysis to Work Through Counter-Trnsference of Professionl Stff: Looking to Imges s Looking in Mirror 73 CO-PRODUCTIVE WORKSHOPS Fcing the Chllenge of Developing Customized Approches in Mentl Helth Prevention Progrmmes for People With Intellectul Disbilities 74 Individul Cse Studies of Service Users With n Intellectul Disbility Supported by Adult Mentl Helth Services West Aucklnd, New Zelnd 74 Involvement nd Community Prticiption 75 INDIVIDUAL PAPERS Sexul Culture s the Subject of Orgniztionl Development Towrds Sexul Culture Within the Ligue HMC 76 Mentl Helth: A Prominent Theme in 24/7 Online Support for Independently Living People With Intellectul Disbilities 77 Comprison of Demnd for Cre by People With Borderline Intellectul Disbilities in the Netherlnds, Englnd, Flnders nd Ontrio 78 Greter Self-Determintion, New Provisions on Control Mesures 78 Hndicp, Eduction nd Child Psychitry: A Model of Intervention 79 POSTERS Does the Dutch Knowledge Progrmme Provide Good Exmple for Bridging Reserch nd Prctice? 79 Insight Into the Orgnistionl Environment of Services for People With Intellectul Disbilities nd Chllenging Behviours 80 CASE REPORT ON INDIVIDUAL INTERVENTION SYMPOSIA Symposium: Combining Successful Tretment nd Joyfulness in Semi-Residentil Fcility 80 Reserch Implictions of the Semi-Residentil Tretment t the Bnjrd 81 Clinicl Implictions for Anxious Children 81 Clinicl Implementtions for Infnt Mentl Helth 82 Symposium: Living With n Intellectul Disbility: How to Engge Individuls Voices nd Stimulte Autonomy nd Self-Determintion? 82 The Importnce of Autonomy Support, Need Stisfction, nd Motivtion in Adults With ID 83 Do Rules in Dily Cre Promote Individuls Autonomy? The Perspective of People With Moderte Intellectul Disbilities 84

6 Tking Into Account the Perspectives of People With Profound Intellectul nd Multiple Disbilities in Decisions Regrding Restrictive Mesures: The Development of Prototype Instrument 84 Symposium: Hndicp & Trum 85 Trum Trumtizes 85 Psychotherpy With Trumtized Children With Intellectul Disbility: Reflections on the Therpeutic Process 86 Trum nd Repetition 86 INDIVIDUAL PAPERS Giving Voice to the Speechless 87 Essentil Fctors in the Tretment of Mentl Helth Problems in MBID: A Cse Study 88 On the Wy to Work 88 Obsessive-Compulsive Disorder in n Adolescent Womn With Turner Syndrome nd Intellectul Disbility: A Cse Report 89 Being Me Being Us - Being Professionl 90 POSTERS Womn of Her Own Life Improving the Creer Mngement Skills of Women With Disbilities 90 The Young Ones: How to Approch Young Adults With Mentl Disbility Who Do Not Seem to Fit In 91 (The Success Story Of) Music Therpy in Luxembourg Fcility for Mentlly Disbled Persons 91 Duerfbuttek nd Duerftreff Beim Lis An Inclusive Solution for Smll Town Desires 92 EDUCATION, REHABILITATION AND EMPLOYMENT SYMPOSIA Symposium: Identifying the Key Elements of the Cretion of Inclusive Employment nd Job Retention for People in High Psychologicl Vulnerbility nd Mentl Disbilities 93 The Different Models of Professionl Inclusion From Prcticl View 93 Perceived Obstcles to the Integrtion of Intellectully Disbled Individuls Into the Job Mrket: A Sheltered Workshop s Point of View 94 INDIVIDUAL PAPERS Peer Mentoring for Secondry School Students With Profound nd Multiple Lerning Difficulties (PMLD) 94 Mesuring Job Stisfction in People With ID Using JIGS nd JDI: An Anlysis Using Item Response Theory 95 Vision, Concretism, Repetitism: Typicl Artistic Design Fetures in Drwings by Adults With Autism nd Intellectul Disbility 96 Predictors of Successful Temwork in Cre Mngement for People With Intellectul Disbility 96 Working With Intellectully Disbled People With South Asin Fmily Bckground: User Views of Services (Prt 1) 97 Student-Oriented Teching Skills for Children With Intellectul Disbilities 98 POSTERS Simulted Ptients With Intellectul Disbilities - Turning the Tble to Meet Helth Needs 99

7 Lights on Rights! A Reflection Focus to Promote Active Citizenship of People With Intellectul Disbilities 99 Job Stisfction, Job Demnds, Job Resources nd the Moderting Results for Personlity Trits of People With Intellectul Disbilities 100 EMOTIONAL, RELATIONAL, AND SPIRITUAL ISSUES SYMPOSIA Symposium: Stff Coching Bsed Upon Emotionl Development, Emotionl Avilbility nd Mentliztion 101 Coching Tem by Going Bck to the Essence of Lerning, Bsed on the Lerning Model High Impct Lerning by Dochy nd Collegues 101 Emotionl Avilbility, Stress-Regultion nd Mentliztion of Cregivers: A Coching Frmework Illustrted With A Cse Study 102 Stff Coching Bsed Upon Emotionl Development, Emotionl Avilbility nd Mentliztion: Key-Fctors nd Implictions 102 Symposium: Attchment in Prctice 103 Incorporting Attchment Theory Into Prctice: Clinicl Prctice Guideline 103 Bringing Attchment Inside the Window of Politiclly Acceptble Policies in ID 104 Lerning From Mentliztion Bsed Therpy for Mentliztion Bsed Support in Dily Cre 104 Symposium: Innovtive Prctices in Emotionl Development in Persons With Intellectul Disbilities 105 Emotionl Development in Persons With ID nd Autism 105 De Drd ( the Wire ): A Metphor for Working on Emotionl Development With Prents nd Cregivers 106 Emotionl Development Used s Bsic Frme in Support: Outrech for People With ID nd Mentl Helth Problems, nd Their Environment 106 Gret Cregivers re Msters in Aviling Bounding 107 Symposium: Mourning 107 Ethicl Issues in Nursing nd Medicl Cre in the Context of Intellectul Disbility nd the User s Will. Ensuring the Best Possible Qulity of Life in Difficult Medicl And/Or End-Of-Life Situtions 107 When Will Dddy Descend From Heven? How to Accompny People or A Group of People With Specil Needs in Mourning: A Multitude of Resources, Tools, Rites 108 INDIVIDUAL PAPERS Do Anxiety nd Depression Influence Attentionl Processing of Emotionl Fces Amongst Adults With Low Ability? 109 POSTERS The Stress of Prenting Child With Down Syndrome 109 Pssport to Life: Investigting the Need for Life-Skills Trining Among Young People With Autism Spectrum Disorders nd Their Prents 110 ETHNICAL AND CULTURAL ISSUES INDIVIDUAL PAPERS Working With Intellectully Disbled People With South Asin Fmily Bckground: User Views of Services 111

8 Experiences With Specilised Mentl Helth Services for Adult Ptients With Intellectul Disbilities in the Migrnt Popultion: A Qulittive Study 111 GENETICS, ETIOPATHOGENESIS, AND TRAINING INDIVIDUAL PAPERS Advntges nd Cvets of Neurobehviorl nd Cognitive Assessment in Rre Genetic Disorders With Moderte to Profound Intellectul Disbilities 112 Neurologicl nd Psychitric Phenotype in Adults With 22q11.2 Deletion Syndrome nd Bsl Gngli Clcifictions 113 HEALTH NEEDS, POLICY, SERVICE SYSTEM, AND TRAINING SYMPOSIA Symposium: Innovtive Tools for Implementtion of Qulity Mngement of Mentl Helth in ID 114 Qulity of n Ambulnt Service: The Courge to Ask 114 Use of Knowledge Mngement for the Development nd Networking of New Skills for Helth Cre Workers in Intellectul Disbility 115 Questioning Our Professionl Prctice in Order to Increse Support Qulity - Soft Violence: It Is for Your Own Good! 115 INDIVIDUAL PAPERS Nutrition in Adults With Multiple Developmentl Disbilities 116 Growing Up With Neurofibromtosis Type 1 nd Tuberous Sclerosis Complex: Concerns nd Cre Needs of Young Adults 116 ehelth Use in Support, Psychologicl Tretment nd Therpy for People With Intellectul Disbility: Results of Two Systemtic Literture Reviews 117 Discovery Awreness (DA): Addressing the Reltionl Perspective of Qulity of Cre nd Support 118 POSTERS Bodyweight nd Associted Risk Fctors in Adults With Intellectul Disbility: Results From Clinicl Cross-Sectionl Study 119 Vlidtion of the Frgile X Syndrome (FXS) Behviorl Phenotype According to Hgermn et l. (2009) 120 A Bioresponse System for Cregivers of Adults With Severe or Profound Intellectul Disbilities 121 INDEPENDENT LIVING AND INCLUSION SYMPOSIA Symposium: Furthering Prticiption nd Inclusion of People With Intellectul Disbility in Society 122 Public Perceptions Towrds People With Intellectul Disbilities 122 Living With Support: Experiences of Individuls With Mild Intellectul Disbilities 123 Collbortion Between Science nd Prctice: Structurlly Including Perspectives of People With Intellectul Disbilities 123 Symposium: Socil Networks of People With Mild Intellectul Disbility: Their Own Perspectives 124 Socil Networks of People With ID: An Explortion of Functionl Chrcteristics nd Wys for Enhncement 124 An Explortion of Fmily Configurtions of People With Mild Intellectul Disbility 125 Fmily Networks of People With Mild Intellectul Disbilities: Their Own Perspectives 126 Symposium: Involvement nd Community Prticiption 126

9 Co-Construction nd Co-Conceptulistion of Resident Council: People With Intellectul Disbilities nd Professionl Mentors Work Together to Pln nd Implement Resident Council 127 From the Residents Council to the Delegte to the Expression of the Users: 20 Yers of Experience. The Evolution of the Pltforms of Prticiption, Plces of Expression nd Exchnges 127 INDIVIDUAL PAPERS Perspectives nd Trnsition Experiences of Adolescents nd Young Adults With Disbilities 128 Are Children With Intellectul Disbilities Fully Included nd Their Rights Fulfilled in Portugl? 129 Dughters of Fortune: Reserch Into the Stories of Prents With Lerning Disbilities With Lerning Disbled Perspective 129 LEGAL (JURIDICAL) AND FORENSIC ISSUES SYMPOSIA Symposium: New Wys to Increse Awreness of Freedom Restrictions: Mesures, Effectiveness of Expert Tems nd Action Reserch with Support Stff 130 Effects of A Multidisciplinry Approch on the Use of Freedom Restrictions in Cre for People With Intellectul Disbilities: A Clustered Rndomized Tril 131 Exploring Freedom Restrictions Through Action Reserch: Prticiptive Observtion Studies of Support Stff in Cre Services for People With Cognitive Impirments 131 Reporting Use of Coercive Mesures From Dutch Perspective 132 INDIVIDUAL PAPERS Personl Experiences of the Criminl Justice System by Individuls With Autism Spectrum Disorders 133 Gender Dysphori in Ptients With Lerning Disbilities in Forensic Settings: A Descriptive Study 134 LIFE EVENTS, ENVIRONMENT, AND FAMILY INDIVIDUAL PAPERS Qulity of Life nd Inclusion: A Journey in the World of Cinem 134 Fmily Functioning in Rre Genetic Syndromes: Wht Is the Burden for the Prents? 135 Being the Mother of Child With n Intellectul Disbility in the Arb Society: The Contribution of Internl nd Externl Resources to Personl Growth Among Arb Mothers of Children With/Without Intellectul Disbilities 135 Socio-Environmentl Fctors nd Intellectul Disbility: A Study of Reltion 136 NEUROLOGICAL AND PHYSICAL ISSUES POSTER Adults With Rre Childhood Onset Epilepsies 137 PERSON-CENTERED APPROACH AND QUALITY OF LIFE SYMPOSIA Symposium: Prenting Children With n Intellectul or Developmentl Disbility 138 From Erly Adversity to Behviour Problems Through Prenting: The Fmily Stress Model in Fmilies of Children With n Intellectul Disbility 138 The Reltionship Between Prents nd Their Child With Significnt Developmentl Dely: An Explortion of Differentited Attchment Behviour 139 Reliztion of the Fmily-Centered Approch in Home-Bsed Support for Fmilies With Children With n Intellectul Disbility in Flnders: Opinions of Prents nd Professionls 139 A Community-Bsed Prenting Intervention for Prents of Children With Disbility: Outcomes in the Austrlin Stepping Stones Triple P Project 140

10 CO-PRODUCTIVE WORKSHOPS Interpersonl Reltions nd ICT 141 INDIVIDUAL PAPERS Understnding the Qulity of Life Predictors of Citizens With nd Without Intellectul Disbility 141 A Systemtic Review Evluting the Effectiveness of Active Support 142 Outcomes From Mentl Helth nd Behviorl Interventions for Children With Dul Dignosis 143 New Findings on the Use of the Itlin Adpttion of the Fmily Qulity of Life Survey 143 QuIQ (Quick Instrument for Qulity of Life): An Instrument for Rpid Assessment of Generic Qulity of Life 144 An Allince for the Qulity of Life of People With Intellectul Disbility 145 POSTERS Trnsntionl Study on the Knowledge of Rights nd the Perception of Discrimintion in People With Intellectul Disbility: A Comprison of Results Between Answers of Reltives, Professionls nd People With Disbilities in Five Europen Countries 145 Preventive Group Intervention for Adolescents With Mild Intellectul Disbility nd Their Prents 146 PSYCHOPATHOLOGY AND PROBLEM BEHAVIOURS SYMPOSIA Symposium: Who s Chllenging Who?: A Co-Produced Trining Course to Improve Stff Empthy nd Attitudes 147 Theoreticl, Empiricl nd Co-Production Bckground for Who s Chllenging Who? 147 Co-Producing the Who s Chllenging Who Trining Course With People With n Intellectul Disbility 148 A Cluster Rndomised Controlled Tril to Test the Effectiveness of Who s Chllenging Who to Improve Support Stff Attitudes nd Empthy Towrds Adults With Intellectul Disbility nd Chllenging Behviours 149 Triner nd Trinee Experiences of Engging With the Who s Chllenging Who? Stff Trining Course 149 Symposium: The AUP Multi-Centre Study: A Clinicl Study on Autism, Intellectul Disbility nd Psychitric Disorders 150 Psychitric Assessment in ASD/ID: A Cse Study 150 Adverse Life Events in the Occurrence of Anxiety nd Depression Among Adults With Autism nd Comorbid Intellectul Disbility 151 Ptients, Fmily Members nd Professionl Crers Experiences of Psychoeductionl Multifmily Groups for Prticipnts With Intellectul Disbilities nd Mentl Illness 152 Symposium: Bet-It: The Process nd Outcomes of Lrge Scle Rndomised Control Tril of Behviourl Activtion Compred to Guided Self-Help for People With Intellectul Disbilities nd Depression 152 A Rtionle for the Tril nd Adpttion of the Behviourl Activtion nd Guided Self-Help Interventions for People With Intellectul Disbilities nd Depression 153 Fidelity to Protocol nd Therpy Qulity in the BetIt Study 153

11 Prticipnt, Supporter nd Therpist Experiences of Psychologicl Interventions for People With Mild/Moderte Intellectul Disbilities nd Depression in the BetIt Tril: A Qulittive Anlysis 154 The BetIt Tril Outcomes: Compring the Effectiveness of Behviourl Activtion for Depression in Adults With Intellectul Disbilities With n Attention Control Intervention 155 Symposium: The Tretment of Psychitric Disorders, Especilly Depression, in People With Intellectul Disbilities 156 A Systemtic Review of Non-Phrmcologicl Interventions for Adults With ID nd Depression 156 The Applicbility of Bright Light Therpy in Adults With Intellectul Disbilities 157 A Multicenter Rndomized Controlled Tril for Bright Light Therpy in Adults With Intellectul Disbility nd Depression: Obstcles nd Chllenges 157 Results of Psychophrmcologicl Tretment of People With Intellectul Disbilities 158 Symposium: Autism Spectrum Disorder 158 Using the Comportementl Approch in Fcing Behvior Problems Help to Find Strtegies nd Pedgogicl Support 159 Psychophrmcology in Autism Spectrum Disorders: Reducing Medictions is Possible t the FAL 159 Empowerment of the Next Genertion of Self-Advoctes; How Cn We Help? 160 Symposium: Equipping Stff to Meet Chllenging Behviour 161 Scndls: Where nd Why They Hppen 161 Cre Stff s Unherd Stkeholders 162 Engging With Uncertinty: Interpreting Ptient Behviour in Discovery Awreness (DA) Sessions 163 Symposium: The Triple-C Model: Tretment nd Support of People With Severe Chllenging Behviour 163 The Triple-C Model: A Different Approch to Supporting People With n Intellectul Disbility nd Chllenging Behviour 164 Supporting Triple-C Professionls: Trining nd Coching 164 First Steps in Developing Scientificlly Grounded Description of the Prctice-Bsed Triple-C Model, Method to Support People With n Intellectul Disbility nd Chllenging Behviour 165 Symposium: Chllenging Behviours 166 People With Chllenging Behviours nd Qulity of Life: A Necessry nd Possible Fit! 166 Tri.A.S.: The Trier Aggression- nd Sfety Progrm 167 Child & Adolescent Psychitric Aspects s Prt of Multidisciplinry Approch in the Tretment of Inptient Mentlly Disbled Youth With Comorbid Psychitric Disorders 167 Chllenging Behviour A Survey Study 168 Symposium: Reducing Restrints in Individuls With Intellectul Disbilities 169 Reducing Restrints nd Restrictive Behvior Mngement Prctices in Individuls With Intellectul Disbilities nd Autism Spectrum Disorders: The Contribution of Applied Behvior Anlysis 169 Reduction of Use of Restrints for Persons Restrined 24 Hours Dy 169

12 A Commitment Sttement for Reducing the Use of Restrints in the Region of Flnders (Belgium): A Joint Chllenge From the Field 170 CO-PRODUCTIVE WORKSHOPS MID/BIF nd Trum in Ptients in Functionl Assertive Community Tretment Tems: An Unmet Issue in Tretment 171 INDIVIDUAL PAPERS Self-Injurious Behviour in Womn With Mild Intellectul Disbility nd Co-Occurring Psychitric Disorders: Using the Self-Hrm Scle 172 Could There Be Role for Electroconvulsive Therpy or Deep Brin Stimultion in the Mngement of Self-Destructive nd Aggressive Behviour? 172 Autism Spectrum Disorder, Intellectul Disbility, nd Emotionl Functioning: Reltedness nd Prticulr Impct on Chllenging Behvior 173 Suicide Behviours in Persons With ID or ASD: Understnding to Prevent 174 Regultion of Personl Spce by Socio-Economicl Interctions in Adults With Autism Spectrum Disorders: An fmri Study 174 Emotionl Egocentric Bis in Autism Spectrum Disorder: Behviorl nd Neurophysiologicl Evidence 175 Screening nd Dignostic Assessment of Neurodevelopmentl Disorders nd Mentl Helth Comorbidity in Mle Prison 176 Cregivers of Individuls With Dul Dignosis of Intellectul Disbilities nd Psychopthology: Burden nd Post-Trumtic Growth 177 Studying the Core ASD Phenotype, Adptive Functioning nd Associted Psychitric Comorbidities in the EU-AIMS Longitudinl Europen Autism Project (EU-AIMS LEAP) 177 Exploring the Effectiveness of Non-Symbolic Augmenttive Communiction for Adults With Intellectul Disbility, Autism Spectrum Disorder nd Chllenging Behviour 178 Psychitric nd Psychologicl Support for Adolescent Womn With 22q11.2 Deletion Syndrome nd Intellectul Disbility: A Good Outcome 179 Re-Defining the Boundries Between Intellectul Development, Autism Spectrum, nd Schizopheni Spectrum Disorders in the Neurodevelopmentl Perspective 180 Autism Spectrum Disorder A Vulnerbility Fctor for Psychitric Comorbidity in Adults With Intellectul Disbility? A Literture Review 180 Personlity Disorders in Intellectul Disbility: A Prevlence Study 181 Psychitric Comorbidity in Adults With Autistic Spectrum Disorders: Preliminry Results in n Itlin Smple 182 The Effects of Trining Progrms for Direct Cre Stff Working With People With Intellectul Disbilities nd Aggressive Behviour: A Met-Anlysis 182 Problem Behvior in Corneli de Lnge Syndrome 183 Problem Behviours nd Mjor Depressive Disorder in Intellectul Disbility nd Autism: A Contribution of PET nd MRI 184 Problem Behviours nd Mjor Depressive Disorder in Adults With Intellectul Disbility nd Autism 185 Evluting Screening Instruments for Depressive Symptomtology in Adults With n Intellectul Disbility nd Autism Spectrum Disorder 186

13 POSTERS The Orgnistionl Environment nd Chllenging Behviour in People With Intellectul Disbilities 186 Psychitric Dignoses in People With Intellectul Disbility nd Dishrmonious Developmentl Profile 187 The Assocition Between Chllenging Behviour nd Cffeine Intke in People With Intellectul Disbilities: A Study in 13 Residentil Settings in the Netherlnds 188 Chllenges of Home-Bsed Service for Children With Developmentl Disorders: Chllenging Behvior nd Prenting Stress 189 Benefits of Nursing Cre Workshops in Hospitliztion Unit Specilized in Intellectul Disbility 189 The Reltionship Between Restrictive Security Mesures nd Aggression Towrds Helth Stff in Residence for People With Intellectul Disbility nd Mentl Helth Dignosis 190 Self-Injurious Behvior in Adults With Autism: A Survey of Residentil Cre Fcilities 191 PSYCHOPHARMACOLOGY SYMPOSIA Symposium: Psychotropic Mediction Use in People With Intellectul Disbilities 192 An Emotionl Developmentl Approch to Mnging Mediction in People With Intellectul Disbilities 193 New nd Very New Genertion Antipsychotics in Intellectul Developmentl Disorders 193 The Overuse of Psychotropic Mediction in People With Intellectul Disbilities 194 Symposium: Wys to Fcilitte Approprite Psychotropic Drug Use in People With Intellectul Disbility (ID) 194 Resons of Physicins Not to Discontinue Off-Lbel Use of Antipsychotics in People With ID 195 A Pilot Study Exmining the Effectiveness of Behviourl Stff Trining Groningen (BSTG) for Individuls With ID nd CB 196 Online Lerning Intervention on Psychotropic Drug Use in People With ID for Direct Support Professionls 196 Discontinution of Off-Lbel Used Antipsychotics in People With ID Living in Service Fcilities: Results nd Determinnts 196 Long-Term Effectiveness of Off-Lbel Risperidone in Children nd Adults With ID: A Double-Blind Plcebo-Controlled Discontinution Study 197 INDIVIDUAL PAPERS Pregblin in Intellectul Disbilities 197 Fcilittors nd Brriers in Implementing nd Using Guidelines on Antipsychotic Drugs in People With Intellectul Disbilities 198 A Pilot Rndomised Controlled Tril of Community-Led Anti-Psychotic Drug Reduction for Adults With Lerning Disbilities (ANDREA-LD) 199 Prevlence of Metbolic Syndrome Among Adults Prescribed Antipsychotic Drugs in n Irish Community-Bsed Intellectul Disbility Popultion 200 Tretment of Addiction in Ptients With n Intellectul Disbility Using 12-Step Fcilittion 200 POSTERS Adherence of Clinicins to Guidelines for the Prescription of Antipsychotic Drugs to People With Intellectul Disbilities 201

14 Helth Relted Qulity of Life (HRQoL) of People With Intellectul Disbility (ID) Who Use Off-Lbel Long-Term Antipsychotics 202 PSYCHOTHERAPY (PSYCHOLOGICAL AND BEHAVIOURAL THERAPY) SYMPOSIA Symposium: Delyed Emotionl Development nd Its Impct 202 Emotionl Support for Children With Intellectul Disbilities in Specilist School Setting 203 Further Developments in the Vlue of Recognising Delyed Emotionl Development in People With ID 203 I Cn Move Agin - A Modern Dy Cse of Hystericl Prlysis 204 Symposium: Prenting nd Erly Interventions in Intellectul Disbilities 204 Evidence for Prent Interventions in Young Children With Intellectul Developmentl Disbilities: Appliction in the EPICC-ID Rndomised Controlled Tril 205 Studying the Effect of Video-Feedbck Intervention to Promote Positive Prenting for Prents of Children With A Visul or Visul nd Intellectul Disbility (VIPP-V): A Rndomized Controlled Tril 206 Possible Predictors of the Qulity of Interction Between Prents With Mild or Borderline Intellectul Disbilities (MID) nd Their Young Children 207 CO-PRODUCTIVE WORKSHOPS Tretment of Mentl Disorders in Children nd Adolescents With Mild to Moderte Lerning Disbility 207 INDIVIDUAL PAPERS AutCom Evlution of Multimodl Group Trining Progrm Supporting Adults With Autism nd Intellectul Disbility 209 Behviour Anlysis: From Controlling to Understnding the Chllenging Behviour 209 Who Am I? A Life Story Intervention for People With Intellectul Disbilities nd Psychitric Problems 210 Cn Thoughts Predict Symptoms of Depression nd Anxiety in Adults With Low Ability 211 Rehbilittion nd Technology: An Integrted Tilored Approch to ASD - Prospectives of Interventions From Trditionl Therpy to Virtul Relity nd Prent Trining 212 Nine, Autistic nd in Stritjcket - How to Get Rid of It? 213 Integrtion Model for Self-Mngement 213 Psychoctive Medictions nd Contextul Behviorl Sciences: Moving From Biologicl Dt to Humn Interction Frme 214 POSTERS The Usefulness of Group Cognitive Remedition in Young Adults With Mild to Moderte Intellectul Disbility: A Pilot Study 215 Medicl Hypnosis to Mnge Distress Relted to Blood Tests in Children With Down Syndrome 216 SPORT, EXERCISE, AND BODY-MIND LINK POSTER Mentl Helth nd Physicl Activity: The Applicbility of Sports-Relted Bsic Needs Model in People With Intellectul Disbilities 217 AUTHOR INDEX 218

15 JOURNAL OF MENTAL HEALTH RESEARCH IN INTELLECTUAL DISABILITIES 2017, VOL. 10, NO. S1, th Europen Congress Mentl Helth in Intellectul Disbility Luxembourg, September 21 23, 2017 Better Mentl Helth for People with Intellectul Disbility Providing better cre using knowledge trnsfer nd bridging together innovtive nd collbortive networks Abstrct Book Committee: Germin Weber (Austri), Mrco Bertelli (Itly), Filip Morisse (Belgium), Crlo Schuengel (The Netherlnds), Roger Bnks (United Kingdom), Régine Scelles (Frnce), Tnj Sppok (Germny), Gerrd Zribi (Frnce)

16 2 EAMHID ABSTRACT BOOK WHERE TO HEAD TO IN THE NEXT TWO DECADES? EAMHID 11TH CONGRESS: THE FIRST IN THE SECOND SERIES OF TEN. SHORT RETROSPECT CHALLENGING OUTLOOK! An Introduction to the Abstrct Volume of the Luxembourg Congress 2017 Germin Weber Deprtment for Applied Psychology: Helth, Development, Enhncement nd Intervention, Fculty of Psychology, University of Vienn, Vienn, Austri Mentl helth mtters. lso for people with intellectul disbilities! This might hve been the unexpressed slogn motivting numerous mbitious reserchers, professionls, NGO mngers, minly from the Netherlnds nd the United Kingdom, to cll for Europen mentl helth gend for people with n intellectul disbility in the lte 1980s nd the erly 1990s. The Europen Assocition on Mentl Helth nd Mentl Retrdtion now known s Europen Assocition on Mentl Helth in Intellectul Disbilities hs its origins in tht period with the im of mking use of erly evidence to promote new thinking bout the mentl helth issue in people with intellectul disbilities. From the erly dys of the founders nd the ssocition s multi-professionl membership, psychitrists, psychologists, eductionl scientists, mentl helth nurses, mngers of support services for people with intellectul disbility were convinced tht stging biennil Europen congress presenting nd promoting dvnces in the re of mentl helth nd intellectul disbility might be substntil step towrds mjor chnge. Indeed, up to this point, mentl helth issues nd problem behviour in people with intellectul disbilities were commonly referred to s being inherent to the intellectul disbility itself, with low intellectul functioning being viewed s resultof dysfunctionl or bnorml brin sitution. In line with this ssumption nd the fct tht there ws no cure for the suggested brin dmge, it ws common prctice to tret mentl helth problems in this popultion without comprehensive mentl helth ssessment nd thus bstining from tretments bsed on dignostic criteri nd clinicl evidence. Now, 20 yers lter, with mjor dvncements in bsic nd pplied reserch, knowledge on mentl helth issues specific to people with intellectul disbilities hs rised substntilly. In the pst 20 yers, the EAMHID orgnised ten conferences, with the inugurl being held in Amsterdm in 1995 nd the 10th being hosted in Florence in Abstrct compiltions of these conferences re good proof tht EAMHID is offering unique pltform in Europe for exchnging dvnces in the field, disseminting evidence-bsed prctices, promoting competences nd skills within professionl groups nd encourging reserch. Obviously, much chnged during this period, with more nd more voices reching out with convincing evidence, using the network offered by EAMHID. However, limittions of these chievements become evident when evluting the success of the knowledge ccumulted in this period being trnsferred into prctice nd when ssessing the impct our knowledge ctully hs for the mentl well-being of individuls with intellectul disbilities.

17 EAMHID ABSTRACT BOOK 3 Everyone hs n equl opportunity to experience mentl well-being throughout their lifespn, prticulrly those who re most vulnerble or t risk (WHO Europe, 2013). Indeed, mentl helth is more thn helth issue, covering res like eduction, fmily ties, employment nd ernings or helthy life-styles s outlined in the Europen Mentl Helth Action Pln of WHO Europe Further, there is brod greement tht good mentl helth is essentil for ll humn beings, including people with intellectul disbilities in order to enjoy good life nd especilly good life in the community. In turn, socil prticiption nd inclusion re vitl ingredients nourishing good mentl helth. This interply nd reciprocl effect between personl outcomes nd socil fctors s well s the biologicl fctors intercting with behviour nd experience re highlighted in the so-clled bio-psycho-socil frmework, widely recognised model. Consequently, this prdigm prominently determines WHO Europe s cycle for mentl well-being. Recently, most of our societies committed themselves to developing equl opportunities for people with disbilities, iming, mong other things, for socil inclusion of people with disbilities in ll res of life, including people with intellectul disbilities, presenting substntil move offering options for new mentl helth promotion strtegies especilly for people with intellectul disbilities. The lck of inclusion nd violence re known to be mjor risk fctors for mentl helth, while n ccessible nd cceptble mentl helth system is of gret importnce for effective support nd eduction, nd community ties re significnt protective fctors for good mentl helth. In ddition, recent evidence on dversities in the ffective-emotionl development of children nd young dults with intellectul disbilities s well s new findings with respect to biologicl fctors nd gene-to-behviour reltions, often reported with specific syndromes, re now offering us new perspectives for understnding the complex nd high vulnerbility for mentl helth problems in people with intellectul disbilities. Thus, with this conference in 2017, the first of the next series of ten, EAMHID strives towrds next mjor step for improving mentl helth for people with ID. In its cll for contributions, EAMHID offered trditionl formts for presenting genuine reserch like individul ppers or symposi, offering the collbortion of up to four scholrs, contributing to one overll topic. In ddition, co-productive workshops were offered within the trditionl congress trcks. This new formt goes fr beyond clssicl formts for presenting reserch t conferences nd ims t bringing stkeholders from different sectors together, including people with intellectul disbilities themselves. We re convinced tht congress offering n inclusive setting nd tking dvntge of more inclusive strtegies will offer better frme for inspiring experiences. Looking t the big picture opens perspectives for something new, often leding to cross-sectorl collbortion, be it in res of reserch or sectors tht re commonly not linked or communicting with ech other. Thus, EAMHID encourges more unified efforts s kick-off for next substntil promotion of good mentl helth for people with ID. According to this unified pproch, those responsible for the scientific progrm of the congress hve brought together some leding experts from selected sectors offering keynote presenttions nd focused communictions to shre their knowledge nd expertise. The bstrct collection of this volume summrizes recent dvnces in the field of mentl helth nd incorportes erly developments in co-productive strtegies illustrting the wy in which this new kind of collbortion contributes to better mentl helth for people with ID. Reserch contributions rnge from bsic reserch such s gene-behviour interction to outcomes in trnspersonl interction nlysis, nd from recent strtegies in ssessing trumtic stress to pplied behviour nlysis in inclusive eductionl settings.

18 4 EAMHID ABSTRACT BOOK This volume is orgnised into different sections beginning with keynote bstrcts, followed by focused communictions. The over 200 peer-reviewed bstrcts selected for presenttion re divided into themtic sectors, including individul bstrcts, symposium bstrcts nd bstrcts relted to co-productive workshops, hving been ssocited with one of the congress s trcks. In ddition, bstrct of pre-congress workshops offered in supplement, s models trnsferring reserch into pplied prctice re included. The bstrct volume concludes with n lphbetic index of the contributing uthors, referring to the pge of the respective bstrct. My this volume be prt of new step towrds improving the mentl helth of people with intellectul disbilities, nd my this led to more effective nd respectful tretment with personcentred nd biogrphicl pproches being more widely used to understnd the individul s mentl helth chllenges, thus going beyond explining it. Mentl helth for people with intellectul disbility is definitely more thn helth issue! References World Helth Orgnistion, Regionl Office Europe. (2013). The Europen Mentl Helth Action Pln. Copenhgen, Denmrk: WHO-Europe. KEY-NOTE SPEECHES Criticl Fctors to Promote Mentl Helth in ID: Looking for Coherent nd Inclusive Approch Aginst Frgmenttion nd Splitting t Different Orgnistionl Level John De Groef,b john.de.groef@telenet.be vzw Zonnelied, Roosdl, Belgium; b Deprtment of Eductionl Sciences, Ctholic University Leuven, Leuven, Belgium Our globlised multiculturl society is chrcterised by chngebility, diversity, nd uncertinty. Ours is predominntly neoliberl society (Verheghe, 2015) ssessing everything nd everyone from business nd mrket prdigm. With their subjcent views on mn nd society, these developments provide in certin wy nd to certin extent the foundtions for prticulr wy of speking nd thinking, certin prctice vis-à-vis persons with ID. Disbility cre hs undergone prdigm shift over the lst fifty yers, from medicl prdigm to citizenship prdigm. A person with ID no longer belongs in psychitric cre: People with ID re now fully-fledged citizens. Erlier, we strove to normlise nd integrte different persons; tody the guiding principle is inclusion. These societl tendencies coincide with scientific nd orgnistionl developments such s Qulity of Life, socio-

19 EAMHID ABSTRACT BOOK 5 ecologicl pproch of disbility, bespoke ssistnce nd need-oriented cre. Mentl helthcre knows similr evolution: societlistion, de-institutionlistion, flexibilistion nd mrketistion become common prctice. Both mentl helthcre nd cre for the elderly especilly the demented show prdigm shift. Once the medicl discourse hs reched its limits, mny ll-importnt questions remin unnswered for those struggling with complex nd lifelong problems. The Qulity of Life pproch the Ter Horst orthopedgogic dge of restortion of ordinry life gins full significnce in these fctul domins of disbility in the brod sense of the term. Wht do these evolutions entil for persons with mentl helth problems in ID? Our yerlong experience with these people in Belgium nd Luxemburg llows us to identify some problemtic phenomen viz. frgmenttion nd splitting tht impose (n) (ideology-)criticl ttitude towrds the dominnt discourse nd its guiding principles. Our experience imposes certin fundmentl reflections on lnguge hygiene (Broekmn, 1996): However importnt principles like inclusion nd societlistion my be, they re not self-evidence but chllenge,ndtheyshouldnotbewieldedsslogns or dogms. As guiding ethicl principles tke form, they need constnt reformultion on humn scle. We distinguish three domins in which the core problem of frgmenttion nd splitting occurs with ll its ensuing itrogenic effects: Legl nd dministrtive orgnistion of helth cre: double dignosis In our Western societies with ll their historic ntionl idiosyncrsies, the differentition between mentl helth cre nd disbility cre hs yielded seprte orgnistion of the ltter. It hs developed its own identity, different nd seprte from mentl helth cre. They ech fll under the jurisdiction of different ministries nd dministrtions, nd hve their seprte finncing nd regultions. They lso use expertise nd knowledge models from different fculties. They employ more or less numerous, differently trined stff. Both function ccording to their own (mutully exclusive?) discourse. The double dignosis in this context is very meningful rtefct. I do not use the term to refer to double dignosis strictu sensu; I m referring to those persons who resort under both domins t the sme time. It is not the clinicl but the business logic (who foots the bill?) which becomes the finl stumbling block through which these people fll between two orgnistionl stools. Double dignosis turns into n excuse for splitting nd exclusion. Lyered relities: colonistion of life fctulity Themeso-leveliswheretheinterfcendtrnsformtion must tke plce, from the objectivting mcro-logic to the level of ctul service, nmely in the life-fctul subjective nd intersubjective context of the rel individuls concerned. Here, the implied expertise, emotionl stmin, vilbility nd persevernce throughout every crisis, nd reoccurrence of bsl problems re of crucil importnce. This sks of ll concerned, especilly professionls, reflective pproch enbling them to ctch the specific centrl psychodynmics nd socio-emotionl development of specific person with ll subjectivities nd detils. The continuity of reltions proves priceless here.

20 6 EAMHID ABSTRACT BOOK Restoring ordinry life or the trnsformtion towrds the (INTRA-)subjective Wht is exmined, thought nd dignosed, in short the mcro-meso-level, cnnot simply be pplied on the micro-level; mutul reduction must be voided. Both levels follow their own logic (Broekmn, 1996). An objectivting integrtive dignostic hs to be rephrsed in cse-relted understnding of the prticulr psychodynmics in which the socio-emotionl dynmics re ctive s well (Dosen & De Groef, 2015). A function-oriented dignostic (Vnheule, 2017) insted of dysfunction-oriented one, together with n nthropopsychitriclly conceived psychopthology (Feys, 2009), my prove inspiring in this cse. Such rephrsing cretes link between the objectivting dignostics nd meningful metphors from stories bout the person concerned, nd cquires the qulities of portrit. Surpssing the different jrgons of the vrious disciplines nd models hs trnsdisciplinry effect. It reformultes the cse in contined mnner, promoting dilogue in everydy, concrete lnguge nd strong imges tht spek for themselves for ll those concerned. The institutionl middle stff ply n eminently crucil role in this contined rephrsing. All the crucil fctors from the different domins cn be clustered s follows: Contct, continuity nd circulrity; Coherence, consecutive consistency; Implied commitment nd control; Comprehensive continment. To the extent to which the implementtions of these Cs misfire or fil, one my expect splitting nd frgmenttion, with ll the pthologicl consequences for ll those concerned. References Broekmn, J. (1996). Intertwinements of lw nd medicine. Identity in socil context. Leuven Lw Series Nr. 7. Leuven, Belgium: Leuven University Press. Dosen, A., & De Groef, J. (2015). Wht is norml behviour in persons with developmentl disbilities?. Advnces in Mentl Helth nd Intellectul Disbilities, 9(5), doi: /amhid Feys, J. L. (2009). L nthropopsychitrie de Jcques Schotte. Une introduction. Pris, Frnce: Hermnn Editeurs. Vnheule, S. (2017). Psychitric dignosis revisited: From DSM to clinicl cse formultion. New York: Plgrve Springer Int. Publictions. Verheghe, P. (2015). Wht bout me? The struggle for identity in mrket-bsed society. Mellbourne-London, UK: Scribe. From Moleculr Studies to Trgeted Tretments in Frgile X Syndrome Rndi Hgermn rjhgermn@ucdvis.edu Deprtment of Peditrics, University of Cliforni t Dvis Medicl Center nd MIND Institute, Scrmento, Cliforni, USA Studies of niml models of frgile X syndrome (FXS) nd the moleculr pthwys tht re dysregulted in the bsence of FMRP hve led to new trgeted tretments of children nd dults with FXS. FMRP controls the trnsltion of hundreds of messges importnt for other disorders

21 EAMHID ABSTRACT BOOK 7 including schizophreni nd utism spectrum disorder (ASD). We know tht the mglur5 pthwy is upregulted in FXS nd the GABA pthwys re downregulted. The initil trils of mglur5 ntgonists did not show efficcy in dolescents nd dults with FXS in the behviourl outcome mesures tht were chosen. However, there is evidence tht younger ptients my do better nd the outcome mesures should include cognitive mesures in ddition to electrophysiologicl studies, mesures of hbitution to sensory stimuli, eye trcking studies, nd behviourl mesures. We hve found tht the event relted potentils (ERPs) prticulrly hbitution prdigms tht trget brin processing bnormlities with deficient GABA inhibitory input were prticulrly helpful in our controlled tril of minocycline in young children with FXS. Other new mesures include expressive lnguge smpling mesures developed by Dr Len Abbeduto nd collegues nd the use of the NIH toolbox dpted by Dr Dvid Hessl for children with FXS to ssess improvements in cognitive processes nd ttention. We hve lso lerned tht erly intervention with trgeted tretments cn significntly improve developmentl testing in young children with FXS s seen by the controlled tril of low dose sertrline in those ges 2 6yo. This controlled tril of mg of sertrline over 6 month period demonstrted significnt improvements in the Visul Perception nd Fine Motor subtests nd in the overll Composite T score in the Mullen Scles of Erly Lerning (MSEL) in those on sertrline vs plcebo. Those with FXS plus ASD lso demonstrted significnt improvement in the Expressive Lnguge subtest of the MSEL on sertrline vs plcebo. Erly intervention is lso studied now with the mglur5 ntgonist, AFQ056, combined with intensive lnguge intervention provided by videoconferencing to the fmily in their home for young children with FXS ges 3 6yo in multicenter tril funded by NIH. Mouse nd Drosophil models of FXS hve demonstrted the benefit of metformin s trgeted tretment nd encourging results re seen in open lbel studies with controlled tril in process. Other medictions tht hve shown efficcy in FXS include minocycline, rbclofen nd trofinetide nd these studies will be reviewed. Since mny pthwys re dysregulted in FXS it my tke more thn one tretment to mke overll cognitive nd behviourl improvements in FXS. The ddition to novel lerning prdigms for FXS re lso expnding nd such prdigms cn be combined with trgeted tretment. We hve shown efficcy in lnguge improvements with Prent Implemented Lnguge Intervention (PILI) tht is guided by speech nd lnguge pthologist combined with BCBA nd the intervention is given through skype twice week in the home. The PILI intervention hs lso been combined with controlled tril of lovsttin, nother trgeted tretment for FXS in n ongoing tril. The future looks bright for new trgeted tretments tht will benefit not only FXS but other neurodevelopmentl disorders including ASD tht hve common spects of moleculr dysregultion. Chllenging Behviour: Individul Difference Mtters Chris Oliver c.oliver@bhm.c.uk Cerebr Centre for Neurodevelopmentl Disorders, School of Psychology, University of Birminghm, Birminghm, UK The substntil body of reserch into the reltionship between the etiology of intellectul disbility nd emotionl, cognitive nd behviourl phenotypes hs resurrected the importnce of individul difference. Identifiction of dimensions of difference in the reserch literture hs brodened models of the cuses of chllenging behviour beyond exclusively opernt lerning theory ccounts tht hve neglected evidence tht demonstrtes more limited role for the environment thn previously climed. Review of the behviourl phenotype literture revels substntil individul difference on the dimensions of physicl helth, sensory experience, socil motivtion nd cognition, nd