*Total award amount reflects Direct Costs only for the duration of the project

Transcription

1 Grants & Contracts Awards Join us as we congratulate the investigators listed below who have recently received a new or competitive renewal award: *Total award amount reflects Direct Costs only for the duration of the project January 2012 Principal Investigator: Ghassan K. Abou- Alfa, MD Department/Program: Medicine/Gastrointestinal Oncology Service Project Title: Quantitative Volume and Density Response Assessment: Sarcoma and HCC as a Model Total Award* Amount: $59,071 Award Date: 01/11/12 Awarding Agency: Columbia University/National Cancer Institute Principal Investigator: Michael F. Berger, PhD Department/Program: Pathology/Genetics Research Project Title: Systematic Studies of Resistance to Targeted Anticancer Therapeutics Total Award* Amount: $359,126 Award Date: 01/17/12 Awarding Agency: Starr Cancer Consortium Principal Investigator: Samuel Danishefsky, PhD Project Title: T32 Grant from Weill Cornell Total Award* Amount: $47,993 Award Date: 01/13/12 Awarding Agency: Weill Medical College of Cornell University/National Institutes of Health Principal Investigator: Sara Olson, PhD Department/Program: Epidemiology & Biostatistics Project Title: International Case- Control Study of Malignant Glioma Total Award* Amount: $560,830 Award Date: 01/20/12 Awarding Agency: Baylor College of Medicine/National Cancer Institute 1 Memorial Sloan- Kettering Cancer Center

2 Principal Investigator: Eric Pamer, MD Department/Program: Medicine/Infectious Disease/Immunology Project Title: CC- Chemokines in Listeria Infection Total Award* Amount: $1,250,000 Award Date: 01/30/12 Awarding Agency: National Institute of Allergy and Infectious Diseases/National Institutes of Health Principal Investigator: John Petrini, PhD Department/Program: Molecular Biology Project Title: Regulation of the DNA Damage Response by the Mre11 Complex Total Award* Amount: $1,251,829 Award Date: 01/30/12 Project Duration: 4 Years Awarding Agency: National Institute of General Medical Sciences Principal Investigator: Craig B. Thompson, MD Project Title: Lymphocyte Survival: Implications for Lymphomagenesis Total Award* Amount: $70,594 Award Date: 01/13/12 Project Duration: 6 Months Principal Investigator: Paul Vadola, PhD Project Title: Synthesis of a Homogenous Erythropoietin via Iterative Native Chemical and Alanine Ligations Total Award* Amount: $99,724 Award Date: 01/13/12 Awarding Agency: National Institute of General Medical Sciences/National Institutes of Health February 2012 Principal Investigator: Mary Alpaugh, PhD Project Title: The Role of Bone Marrow- Derived Progenitor Cells and Tumor Emboli- Derived Exosomes in Malignant Progression of IBC Total Award* Amount: $10,000 Award Date: 02/06/12 2 Memorial Sloan- Kettering Cancer Center

3 Awarding Agency: The Mary Kay Foundation/Weill Medical College of Cornell University Principal Investigator: Hisham Bazzi, PhD Department/Program: Developmental Biology Project Title: Centrosomes and Hedgehog Signaling in Development and Polycystic Kidney Disease Total Award* Amount: $113,404 Award Date: 02/02/12 Awarding Agency: National Institute of Diabetes & Digestive & Kidney Diseases/National Institutes of Health Principal Investigator: Richard D. Carvajal, MD Department/Program: Medicine/Melanoma & Sarcoma Service Project Title: Per Case Reimbursement for Operational Costs at the Site Related for the NCI- CTEP Trial #8443 Total Award* Amount: $100,000 Award Date: 02/15/12 Project Duration: 3 Months Awarding Agency: Westat, Inc./National Cancer Institute Principal Investigator: Gabriela Chiosis, PhD Department/Program: Medicine/Breast Cancer Medicine/Molecular Pharmacology & Chemistry Project Title: Biomarkers of Response to Hsp90 Inhibitors in Triple- Negative Breast Cancer Total Award* Amount: $239,250 Award Date: 02/29/12 /National Institutes of Health Principal Investigator: Sarat Chandarlapaty, MD Department/Program: Medicine/Breast Cancer Medicine Service Project Title: Therapeutic Targeting of the Pl3K Enzymes in Breast Cancer Total Award* Amount: $10,000 Award Date: 02/07/12 Awarding Agency: Clinical and Translational Science Center/ National Center for Research Resources Principal Investigator: Samuel Danishefsky, PhD Project Title: R01 Aim 3 Danishefsky Total Award* Amount: $100,000 3 Memorial Sloan- Kettering Cancer Center

4 Award Date: 02/27/12 Project Duration: 6 Months Awarding Agency: Duke University Medical Center/ National Institutes of Health Principal Investigator: Mithat Gonen, PhD Department/Program: Epidemiology & Biostatistics Project Title: Maximum Entropy Estimation of Molecular and Genetic Diversity Total Award* Amount: $25,989 Award Date: 02/27/12 Awarding Agency: Dana Farber Cancer Institute/National Cancer Institute Principal Investigator: James J. Hsieh, MD, PhD Department/Program: Medicine/Genitourinary Oncology Service Project Title: Integrated Analyses of Taspase 1 (MLL Cleaving Protease) Total Award* Amount: $60,916 Award Date: 02/14/12 Project Duration: 13.5 Months /National Institutes of Health Principal Investigator: Yelena Y. Janjigian, MD Department/Program: Medicine/Gastrointestinal Oncology Service Project Title: Phase 2 Irinotecan for Treatment of p53 wr Gastric Adenocarcinoma Total Award* Amount: $18,491 Award Date: 02/22/12 Awarding Agency: Weill Medical College of Cornell University/ Food and Drug Administration Principal Investigator: William R. Jarnagin, MD, FACS Department/Program: Surgery/Hepatopancreatobiliary Service Project Title: Clinical Translation of Deformation Compensation for Image- Guided Liver Total Award* Amount: $106,193 Award Date: 02/03/12 Awarding Agency: Vanderbilt University/National Institutes of Health Principal Investigator: Ingo K. Mellinghoff, MD Department/Program: Neurology/Neurology Service Project Title: Ivy Foundation Early Phase Clinical Trials Consortium Total Award* Amount: $312,231 Award Date: 02/15/12 4 Memorial Sloan- Kettering Cancer Center

5 Awarding Agency: University of California, San Francisco/Ben and Catherine Ivy Foundation, The Principal Investigator: Gavril W. Pasternak, MD, PhD Department/Program: Neurology/Neurology Service/Molecular Pharmacology & Chemistry Project Title: Biochemical Characterization of Opioid Binding Sites Total Award* Amount: $604,258 Award Date: 02/07/12 Awarding Agency: National Institute on Drug Abuse/National Institutes of Health Principal Investigator: Stewart Shuman, MD, PhD Department/Program: Medicine/Departmental/Molecular Biology Project Title: mrna Capping Enzymes Total Award* Amount: $1,511,488 Award Date: 02/09/12 Project Duration: 4 Years Awarding Agency: National Institute of General Medical Sciences/National Institutes of Health Principal Investigator: Daniel Thorek, PhD Project Title: Multimodal, High Resolution and Dynamic Imaging of Sentinel and Distal Metastatic Lymph Nodes Using Intra- Lymphatic 18F- FDG Mapping Total Award* Amount: $60,000 Award Date: 02/08/12 Awarding Agency: Society of Nuclear Medicine Principal Investigator: Ann Zauber, PhD Department/Program: Epidemiology & Biostatistics Project Title: Optimizing Colonoscopy & Fecal Immunochemical Tests for Community- Based Screening Total Award* Amount: $30,638 Award Date: 02/28/12 Awarding Agency: Kaiser Foundation Research Institute/National Institutes of Health March 2012 Principal Investigator: Kathryn Anderson, PhD Department/Program: Developmental Biology Project Title: Tissue- specific Roles of Axin in Canonical Wnt Signaling and Tumorigenesis Total Award* Amount: $239,250 5 Memorial Sloan- Kettering Cancer Center

6 Award Date: 03/23/12 Principal Investigator: Michelle S. Bradbury, MD, PhD Department/Program: Radiology/Neuroradiology Service Project Title: Renally Excreted Multimodal Core- Shell Silica Nanoparticles as Tumor- Selective Radiotherapeutic Platforms for Nanomedicine Total Award* Amount: $1,885,531 Award Date: 03/12/12 Principal Investigator: Maura N. Dickler, MD Department/Program: Medicine/Breast Cancer Medicine Service Project Title: An Assessment of Mdm2C Isoform Protein as a Prognostic Factor in Breast Cancer Total Award* Amount: $35,365 Award Date: 03/05/12 Awarding Agency: Hunter College/Clinical and Translational Science Center Principal Investigator: Jan Grimm, MD, PhD Department/Program: Radiology/Nuclear Medicine Service Project Title: Cerenkov- Emission Based Nanosensors to Detect Biologic Activities In Vivo Total Award* Amount: $900,000 Award Date: 03/08/12 Project Duration: 4 Years Awarding Agency: National Institute of Biomedical Imaging and Bioengineering/National Institutes of Health Principal Investigator: Eric Holland, MD Department/Program: Neurosurgery/Departmental/Cancer Biology and Genetics Project Title: Physical Science Oncology Center Training Program Total Award* Amount: $538,908 Award Date: 03/20/12 Principal Investigator: Hedvig Hricak, MD, PhD Department/Program: Radiology/Departmental/Molecular Pharmacology & Chemistry Project Title: Subcontract to Anonymize and Transfer Radiological Imaging Data for The Cancer Imaging 6 Memorial Sloan- Kettering Cancer Center

7 Archive Total Award* Amount: $6,000 Award Date: 03/23/12 Awarding Agency: SAIC- Frederick/National Cancer Institute Research and Technology Management Principal Investigator: Clifford Hudis, MD Department/Program: Medicine/Breast Cancer Medicine Service Project Title: TBCRC 20: The Incidence of Adjacent Synchronous Ipsilateral Infiltrating Carcinoma, DCIS, or Atypical Ductal Hyperplasia (ADH) in Patients Diagnosed with Lobular Neoplasia of the Breast by Core Needle Biopsy Total Award* Amount: $4,200 Award Date: 03/13/12 Awarding Agency: Johns Hopkins University/Breast Cancer Research Foundation Principal Investigator: Katharine C. Hsu, MD, PhD Department/Program: Bone Marrow Transplant Service Project Title: Hematopoeitic Stem Cell Transplantation Total Award* Amount: $23,966 Award Date: 03/20/12 Awarding Agency: Fred Hutchinson Cancer Research Center/National Institute of Allergy and Infectious Diseases Principal Investigator: Neil Lipman, VMD Department/Program: Metastasis Research Center Project Title: Tri- Institutional Training Program in Laboratory Animal Medicine and Science Total Award* Amount: $473,764 Award Date: 03/30/12 Project Duration: 4 Years Awarding Agency: National Institutes of Health - Office of the Director Principal Investigator: Scott Keeney, PhD Department/Program: Molecular Biology Project Title: Mechanism of Meiotic Recombination Initiation in Yeast Total Award* Amount: $887,896 Award Date: 03/26/12 Project Duration: 4 Years Awarding Agency: National Institute of General Medical Sciences 7 Memorial Sloan- Kettering Cancer Center

8 Principal Investigator: Richard N. Kolesnick, MD Department/Program: Medicine/Endocrinology/Molecular Pharmacology & Chemistry Project Title: Re- setting the Endothelial Ceramide Rheostat Total Award* Amount: $1,037,500 Award Date: 03/30/12 Awarding Agency: National Heart, Lung, and Blood Institute Principal Investigator: Douglas A. Levine, MD Department/Program: Surgery/Gynecology Service Project Title: Prevention of Ovarian High- Grade Serous Carcinoma by Elucidating its Early Changes Total Award* Amount: $244,139 Award Date: 03/07/12 Awarding Agency: Johns Hopkins University/National Institutes of Health Principal Investigator: Ross Levine, MD Department/Program: Medicine/Human Oncology & Pathogenesis Program (HOPP) Project Title: Molecular Pathogenesis and Therapy of Myeloproliferative Neoplasms Total Award* Amount: $523,810 Award Date: 03/22/12 Awarding Agency: Leukemia and Lymphoma Society Principal Investigator: Elisa Oricchio, PhD Project Title: Indentifying New Therapeutic Targets in Follicular Lymphoma. Total Award* Amount: $185,715 Award Date: 03/22/12 Awarding Agency: Leukemia and Lymphoma Society Principal Investigator: Andrea Pusic, MD, MHS Department/Program: Surgery/Plastic and Reconstructive Surgical Service Project Title: Mastectomy Reconstruction Outcomes Consortium (MROC) Study Total Award* Amount: $418,320 Award Date: 03/06/12 Awarding Agency: University of Michigan Cancer Center/National Institutes of Health Principal Investigator: Jessica Rios, BS Department/Program: Cell Biology 8 Memorial Sloan- Kettering Cancer Center

9 Project Title: Biochemical and Functional Analysis of Wnt Acyltransferase, Porcupine Total Award* Amount: $126,696 Award Date: 03/29/12 Awarding Agency: National Institute of General Medical Sciences Principal Investigator: Alberto Rosello- Diez, PhD Department/Program: Developmental Biology Project Title: Examining Growth Coordination Between Left and Right Sides of the Developing Vertebrate Body Total Award* Amount: $164,980 Award Date: 03/30/12 Awarding Agency: Human Frontier Science Program Principal Investigator: Stewart Shuman, MD, PhD Department/Program: Medicine/Departmental/Molecular Biology Project Title: Viral and Microbial RNA Modifying Enzymes Total Award* Amount: $1,473,415 Award Date: 03/23/12 Project Duration: 4 Years Awarding Agency: National Institute of General Medical Sciences April 2012 Principal Investigator: Arjun Balar, MD Department/Program: Medicine Project Title: Phase II Study of Gemcitabine and Pazopanib in Cisplatin Ineligible Patients with Metastatic Urothelial Cancer and the Potential Impact of Inherited Genetic Variation on Outcomes Total Award* Amount: $47,500 Award Date: 04/02/12 Awarding Agency: Conquer Cancer Foundation of the American Society of Clinical Oncology Principal Investigator: Omar Abdel- Wahab, MD Department/Program: Human Oncology & Pathogenesis Program (HOPP) Project Title: Understanding and Targeting Epigenetic Alterations in Acquired Bone Marrow Failure Total Award* Amount: $300,000 Award Date: 04/20/12 Awarding Agency: DOD - Department of Defense 9 Memorial Sloan- Kettering Cancer Center

10 Principal Investigator: Richard D. Carvajal, MD Department/Program: Medicine/Melanoma & Sarcoma Service Project Title: Human Melanoma: Etiology, Progression and Therapy Total Award* Amount: $43,798 Award Date: 04/13/12 Awarding Agency: University of California, San Francisco/National Cancer Institute Principal Investigator: Stephen Chung, MD Department/Program: Human Oncology & Pathogenesis Program (HOPP) Project Title: Characterization of CD99 as a Therapeutic Target in MDS and AML Total Award* Amount: $47,500 Award Date: 04/02/12 Awarding Agency: Conquer Cancer Foundation of the American Society of Clinical Oncology Principal Investigator: Alexander Drilon, MD Department/Program: Medicine Project Title: A Phase II Trial of Subcutaneous Bortezomib and Analysis of the NF- kb Pathway in a Molecularly- Selected Cohort of Advanced Previously- Treated KRAS G12D- Mutant Lung Adenocarcinoma Total Award* Amount: $47,500 Award Date: 04/02/12 Awarding Agency: Conquer Cancer Foundation of the American Society of Clinical Oncology Principal Investigator: James Harding, MD Department/Program: Medicine Project Title: An Evaluation of the Therapeutic and Molecular Effects of Histone Deacetylase Inhibition in Metastatic Uveal Melanoma Total Award* Amount: $47,500 Award Date: 04/02/12 Awarding Agency: Conquer Cancer Foundation of the American Society of Clinical Oncology Principal Investigator: Elizabeth H. Lacy, PhD Department/Program: Developmental Biology Project Title: Genetic Pathways Directing Ventral Folding Morphogenesis in Mammalian Embryos Total Award* Amount: $1,307,760 Award Date: 04/13/12 Awarding Agency: National Institute of Child Health and Human Development 10 Memorial Sloan- Kettering Cancer Center

11 Principal Investigator: Julian Lange, PhD Department/Program: Molecular Biology Project Title: Regulating the Number and Distribution of DNA Breaks in Mammalian Meiosis Total Award* Amount: $52,000 Award Date: 04/02/12 Awarding Agency: American Cancer Society Principal Investigator: Christina Leslie, PhD Department/Program: Computational Biology Project Title: Integrative Analysis Tools to Dissect Cell- Type Specific Transcriptional Programs in Mammalian Cells Total Award* Amount: $1,142,215 Award Date: 04/23/12 Awarding Agency: National Human Genome Research Institute Principal Investigator: Hans G. Lilja, MD, PhD Department/Program: Clinical Chemistry Project Title: SPORE in Prostate Cancer Total Award* Amount: $20,000 Award Date: 04/03/12 Awarding Agency: Mayo Clinic Rochester/National Cancer Institute Principal Investigator: Sadek Nehmeh, PhD Department/Program: Medical Physics Project Title: Prognostic Value of Tumor Hypoxia, as Measured by 18F- FMISO Breath Hold PET/CT Total Award* Amount: $960,753 Award Date: 04/27/12 Principal Investigator: Jamie Ostroff, PhD Department/Program: Psychiatry Project Title: Implementing Tobacco Use Treatment Guidelines in Dental Public Health Clinics Total Award* Amount: $145,445 Award Date: 04/30/12 Awarding Agency: New York University School of Medicine/National Cancer Institute 11 Memorial Sloan- Kettering Cancer Center

12 Principal Investigator: Paul Paik, MD Department/Program: Medicine Project Title: Squamous Cell Carcinoma of the Lung Mutation Analysis Program (SQ- MAP) Total Award* Amount: $187,399 Award Date: 04/05/12 Awarding Agency: Conquer Cancer Foundation of the American Society of Clinical Oncology Principal Investigator: Charles Sawyers, MD Department/Program: Human Oncology & Pathogenesis Program (HOPP) Project Title: Understanding Resistance to Next Generation Antiandrogens Total Award* Amount: $1,176,525 Award Date: 04/27/12 Principal Investigator: Charles A. Sklar, MD Department/Program: Long- Term Follow- Up Project Title: Childhood Cancer Survivor Study Total Award* Amount: Award Date: $325,500 Awarding Agency: Saint Jude Children's Research Hospital/National Cancer Institute Principal Investigator: Derek Tan, PhD Project Title: Small Molecule Inhibitors of P. aeruginosa Quinolone (Pqs) Quorum Sensing Total Award* Amount: $266,632 Award Date: 04/02/12 Awarding Agency: National Institute of Allergy and Infectious Diseases Principal Investigator: Martin Voss, MD Department/Program: Genitourinary Oncology Project Title: Predictive Tissue Biomarkers for mtor Inhibitors in Advanced Renal Cell Carcinoma (RCC) Total Award* Amount: $47,500 Award Date: 04/02/12 Awarding Agency: Conquer Cancer Foundation of the American Society of Clinical Oncology 12 Memorial Sloan- Kettering Cancer Center

13 Principal Investigator: Rona Yaeger, MD Project Title: Targeting PI3K/AKT effector signaling in KRAS mutant colorectal tumors Total Award* Amount: $98,000 Award Date: 04/02/12 Awarding Agency: American Cancer Society May 2012 Principal Investigator: Peter J. Allen, MD, FACS Department/Program: Surgery/Hepatopancreatobiliary Service Project Title: Pancreatic Cystic Reference Set Total Award* Amount: $20,023 Award Date: 05/02/12 Awarding Agency: University of Pittsburgh School of Medicine/ National Cancer Institute Principal Investigator: Kathryn Anderson, PhD Department/Program: Developmental Biology Project Title: Genetic Analysis of Mouse Nervous System Development Total Award* Amount: $1,597,975 Award Date: 05/08/12 Awarding Agency: National Institute of Neurological Disorders and Stroke Principal Investigator: Peter Bach, MD, MAPP Department/Program: Epidemiology & Biostatistics Project Title: Radiomics of Lung Cancer Screening Total Award* Amount: $73,089 Award Date: 05/30/12 Awarding Agency: H. Lee Moffitt Cancer Center & Research Institute Principal Investigator: Rashmi Bhardwaj, PhD Department/Program: Human Oncology & Pathogenesis Program (HOPP) Project Title: The Role of Ribosomal Protein Deficiency in Pathogenesis of Bone Marrow Total Award* Amount: $294,953 Award Date: 05/30/12 Awarding Agency: DOD - Department of Defense Principal Investigator: Ronald Blasberg, MD 13 Memorial Sloan- Kettering Cancer Center

14 Department/Program: Neurology/Neurology Service/Molecular Pharmacology & Chemistry Project Title: Tumor Microenvironment: Impact on T Cell Tumor-Targeting, Activation and Survival Total Award* Amount: $1,387,392 Award Date: 05/09/12 Principal Investigator: Gardner Creech, PhD Project Title: NCL with Induced a-helices: de Novo Chemical Synthesis of the ATAD2 Bromodomain Total Award* Amount: $148,518 Award Date: 05/16/12 Awarding Agency: National Institute of General Medical Sciences Principal Investigator: Samuel Danishefsky, PhD Department/Program: Molecular Pharmacology & Chemistry Project Title: Synthesis of Antitumor Natural Products Total Award* Amount: $1,037,500 Award Date: 05/14/12 Principal Investigator: Joseph P. Erinjeri, MD, PhD Department/Program: Radiology/Interventional Radiology Service Project Title: Modulating Inflammation to Improve Treatment Response Following Thermal Ablation of Tumors Total Award* Amount: $152,000 Award Date: 05/21/12 Awarding Agency: Radiological Society of North America Principal Investigator: Eric Holland, MD Department/Program: Neurosurgery/Departmental/Cancer Biology and Genetics Project Title: RCAS-tva System Ependymoma Modeling Total Award* Amount: $200,000 Award Date: 05/02/12 Awarding Agency: CERN Foundation Principal Investigator: Ross Levine, MD 14 Memorial Sloan- Kettering Cancer Center

15 Department/Program: Medicine/Human Oncology & Pathogenesis Program (HOPP) Project Title: Investigation of the effects of Asxl1 loss on hematopoietic stem cell self- renewal Total Award* Amount: $5,000 Award Date: 05/03/12 Awarding Agency: American Society of Hematology Principal Investigator: Marcel Van Den Brink, MD, PhD Department/Program: Medicine/Division of Hematologic Oncology/Immunology Project Title: IL-22 in Thymic Regeneration Total Award* Amount: $1,374,175 Award Date: 05/31/12 Awarding Agency: National Institute of Allergy and Infectious Diseases Principal Investigator: Ryan Willett, PhD Department/Program: Developmental Biology Project Title: Roles of Engrailed Proteins in Granule Cells During Cerebellum Development Total Award* Amount: $148,518 Award Date: 05/25/12 Awarding Agency: National Institute of Neurological Disorders and Stroke August 2012 Principal Investigator: James Allison, PhD/Alexander Rudensky, PhD Department/Program: Medicine/Departmental/Immunology Project Title: Immunology Research Training Total Award* Amount: $1,107,912 Award Date: 08/01/12 Principal Investigator: Charlotte E. Ariyan, MD, PhD Department/Program: Surgery/Gastric and Mixed Tumor Service Project Title: Combining CTLA-4 Blockade with Regional Chemotherapy to Augment Antitumor Immunity in Melanoma Total Award* Amount: $100,000 Award Date: 08/21/12 Awarding Agency: Society of Surgical Oncology 15 Memorial Sloan- Kettering Cancer Center

16 Principal Investigator: Elena Elkin, PhD Department/Program: Biostatistics Project Title: Medical Decision Making in Cancer Total Award* Amount: $10,000 Award Date: 08/20/12 Research and Technology Management Principal Investigator: Jenna Goldberg, MD Department/Program: Bone Marrow Transplant Service Project Title: Immune Mediated Disorders After Allogeneic Hematopoietic Cell Transplants (HCT)- Project 1 Total Award* Amount: $13,598 Award Date: 08/23/12 Awarding Agency: Fred Hutchinson Cancer Research Center/National Cancer Institute Principal Investigator: Jenna Goldberg, MD Department/Program: Bone Marrow Transplant Service Project Title: Immune Mediated Disorders After Allogeneic Hematopoietic Cell Transplants (HCT)- Project 2 Total Award* Amount: $16,802 Award Date: 08/23/12 Awarding Agency: Fred Hutchinson Cancer Research Center/National Cancer Institute Principal Investigator: Alan M. Hanash, MD, PhD Department/Program: Medicine Project Title: IL-22 in Epithelial Regeneration After Allogeneic Transplant Total Award* Amount: $633,125 Award Date: 08/24/12 Awarding Agency: National Heart, Lung, and Blood Institute Principal Investigator: Kitai Kim, PhD Project Title: Hematopoietic Potential of Histocompatible Embryonic Stem Cell Lines Total Award* Amount: $488,710 Award Date: 08/21/12 Project Duration: 7 Years Awarding Agency: National Heart, Lung, and Blood Institute Principal Investigator: Moritz F. Kircher, MD, PhD Department/Program: Radiology Project Title: Combined Pre & Intraoperative Brain Tumor Imaging Strategy using a Dual- 16 Memorial Sloan- Kettering Cancer Center

17 Modality MRI-Raman Nanoparticle Total Award* Amount: $827,500 Award Date: 08/06/12 Principal Investigator: Robert Klein, PhD Project Title: Identification of Regulatory Cancer Risk SNPs for Chemoprevention Discovery Total Award* Amount: $100,000 Award Date: 08/02/12 Principal Investigator: Ross Levine, MD Department/Program: Medicine/Human Oncology & Pathogenesis Program (HOPP) Project Title: Targeting Cytosine Hydroxymethylation in AML Stem Cells Total Award* Amount: $540,054 Award Date: 08/24/12 Awarding Agency: Leukemia and Lymphoma Society Principal Investigator: Yueming Li, PhD Project Title: Regulation and Function of Gamma-Secretase Total Award* Amount: $459,500 Award Date: 08/21/12 Awarding Agency: National Institute on Aging Principal Investigator: Hans G. Lilja, MD, PhD Department/Program: Clinical Chemistry Project Title: Prospective Validation of a Multi-Marker Prostate Cancer Prediction Model Total Award* Amount: $1,483,802 Award Date: 08/08/12 Project Duration: 4 Years Principal Investigator: Scott Lowe, PhD Project Title: Computational and Functional Approaches to Validating Cancer Genome Targets. Proj 5 Total Award* Amount: $1,072,120 Award Date: 08/30/12 17 Memorial Sloan- Kettering Cancer Center

18 Awarding Agency: Cold Spring Harbor Laboratory/National Institutes of Health Principal Investigator: Srinivas Malladi, PhD Project Title: Candidate Mediators of Latent Metastasis: Identification and Validation Total Award* Amount: $150,000 Award Date: 08/13/12 Awarding Agency: American Cancer Society Principal Investigator: Joan Massagué, PhD Project Title: Dissecting and Targeting Latent Metastasis Total Award* Amount: $5,000,000 Award Date: 08/20/12 Awarding Agency: Congressionally Directed Medical Research Programs Principal Investigator: Christian J. Nelson, PhD Department/Program: Psychiatry and Behavioral Sciences Project Title: Decision Making For Active Surveillance in Prostate Cancer Patients and Spouses Total Award* Amount: $311,222 Award Date: 08/20/12 Principal Investigator: Sun Park, PhD Project Title: Characterization of the Role of Msi2 in Hematopoiesis Total Award* Amount: $140,000 Award Date: 08/22/12 Awarding Agency: Tri-Institutional Stem Cell Initiative Principal Investigator: Dinshaw J. Patel, PhD Department/Program: Structural Biology Project Title: Functions and Mechanisms of E-Box Binding Transcription Factors in AML1- ETO Mediated Leukemogenesis Total Award* Amount: $600,000 Award Date: 08/29/12 Awarding Agency: Starr Cancer Consortium 18 Memorial Sloan- Kettering Cancer Center

19 Principal Investigator: Fabiana Perna, PhD Project Title: Investigations into a Novel Epigenetic Silencing Mechanism of Globin Gene Expression Total Award* Amount: $100,000 Award Date: 08/17/12 Awarding Agency: American Society of Hematology Principal Investigator: Michel Sadelain, MD, PhD Department/Program: Medicine/Hematology/Molecular Pharmacology & Chemistry Project Title: Genetic Approaches to Cancer Immunotherapy Total Award* Amount: $8,641,801 Award Date: 08/30/12 Project Duration: 7 Years Principal Investigator: Gary Schwartz, MD Department/Program: Medicine/Melanoma and Sarcoma Project Title: Co-Chair of the Experimental Therapeutics Committee Total Award* Amount: $6,818 Award Date: 08/16/12 Awarding Agency: Alliance for Clinical Trials in Oncology Foundation Principal Investigator: Lorenz Studer, MD Department/Program: Neurosurgery/Departmental/Developmental Biology Project Title: PD ips Cell Line Consortium Total Award* Amount: $199,714 Award Date: 08/15/12 Awarding Agency: McLean Hospital/National Institute of Neurological Disorders and Stroke Principal Investigator: Brian Zeglis, BS Department/Program: Radiology Project Title: PET Imaging of Oxidative Stress in Prostate Cancer Total Award* Amount: $75,000 Award Date: 08/28/12 Awarding Agency: Congressionally Directed Medical Research Programs September 2012 Principal Investigator: Goutam Chakraborty, PhD Department/Program: Cell Biology 19 Memorial Sloan- Kettering Cancer Center

20 Project Title: Inhibition of Prostate Tumor Progression by Neogenin Total Award* Amount: $115,000 Award Date: 09/30/12 Awarding Agency: Congressionally Directed Medical Research Programs Principal Investigator: Timothy Chan, MD, PhD Department/Program: Radiation Oncology Project Title: The Mutational Landscapes Underlying Aggressiveness in Adenoid Cystic Carcinoma Total Award* Amount: $275,000 Award Date: 09/24/12 Awarding Agency: National Institute of Dental and Craniofacial Research Principal Investigator: Ping Chi, MD Department/Program: Medicine Project Title: An Integrative Approach to Target Lineage-Specific Oncogenic Transcription Factors Total Award* Amount: $1,500,000 Award Date: 09/13/12 Principal Investigator: Lisa Diamond, MD Department/Program: Psychiatry & Behavioral Sciences Project Title: Impact of Physician non-english Language Proficiency Level on Cancer Screening Total Award* Amount: $254,650 Award Date: 09/27/12 Principal Investigator: Mark Dunphy, DO Department/Program: Nuclear Medicine Project Title: First Human Trial of Src/Abl-Targeted Cancer Imaging with F-18 SKI PET Total Award* Amount: $415,000 Award Date: 09/18/12 Principal Investigator: Francesca Gany, MD Department/Program: Psychiatry & Behavioral Sciences Project Title: South Asian Health: From Research to Practice and Policy 20 Memorial Sloan- Kettering Cancer Center

21 Total Award* Amount: $49,941 Award Date: 09/26/12 Awarding Agency: National Institute of Child Health and Human Development Principal Investigator: Jan Grimm, MD, PhD Department/Program: Radiology/Nuclear Medicine Project Title: Prognosticating Nanoparticles for Molecular Imaging of Prostate Cancer Total Award* Amount: $225,000 Award Date: 09/11/12 Awarding Agency: Congressionally Directed Medical Research Programs Principal Investigator: Daniel Heller, PhD Project Title: Transient Metabolite Detection for Single-Cell Metabolomics and Diagnostics Total Award* Amount: $1,500,000 Award Date: 09/21/12 Awarding Agency: National Institute of Child Health and Human Development Principal Investigator: Clifford Hudis, MD Department/Program: Medicine/Breast Cancer Medicine Project Title: Role of Mechanical Properties of Obesity-Asociated Stroma in Breast Cancer Total Award* Amount: $11,250 Award Date: 09/11/12 Awarding Agency: Clinical and Translational Science Center/National Center for Advancing Translational Sciences Principal Investigator: Robert Klein, PhD Project Title: Linking Disease-Associated Variants to Transcriptional Regulation Using ENCODE Total Award* Amount: $1,079,717 Award Date: 09/19/12 Awarding Agency: National Human Genome Research Institute Principal Investigator: Mark Kris, MD Department/Program: Medicine/Thoracic Oncology Project Title: Targets for Therapy for Carcinomas of the Lung Total Award* Amount: $10,721,659 Award Date: 09/12/12 21 Memorial Sloan- Kettering Cancer Center

22 Principal Investigator: Ross Levine, MD Department/Program: Medicine/Human Oncology & Pathogenesis Program (HOPP) Project Title: Enhancing Targeted Therapy for Myeloproliferative Neoplasms Total Award* Amount: $53,704 Award Date: 09/27/12 Awarding Agency: H. Lee Moffitt Cancer Center & Research Institute/Congressionally Directed Medical Research Programs Principal Investigator: Susruta Majumdar, PhD Department/Program: Neurology Project Title: Analgesics Targeting Truncated Transmembrane Exon 11 Variants of MOR-1 (6TM-E11) Total Award* Amount: $246,926 Award Date: 09/10/12 Awarding Agency: National Institute on Drug Abuse Principal Investigator: Christine Mayr, MD Project Title: Dissecting the Role of Alternative 3'UTRs in Cancer with 3'-seq Total Award* Amount: $1,300,588 Award Date: 09/07/12 Project Duration: 4 Years Principal Investigator: Christian J. Nelson, PhD Department/Program: Psychiatry and Behavioral Sciences Project Title: Identifying and Measuring Depression in Older Cancer Patients Total Award* Amount: $290,560 Award Date: 09/24/12 Principal Investigator: Philipp Niethammer, PhD Department/Program: Cell Biology Project Title: Regulation of Wound Detection in Animal Tissues Total Award* Amount: $950,000 Award Date: 09/13/12 Awarding Agency: National Institute of General Medical Sciences 22 Memorial Sloan- Kettering Cancer Center

23 Principal Investigator: Alexandros Pertsinidis, PhD Department/Program: Structural Biology Project Title: Understanding Gene Transcription from First-Principles: A Single-Molecule Study Total Award* Amount: $1,500,000 Award Date: 09/21/12 Awarding Agency: National Institute of General Medical Sciences/National Institutes of Health Principal Investigator: Chris Sander, PhD Department/Program: Epidemiology & Biostatistics/Biostatistics/Computational Biology Project Title: Pathway Commons: A Public Library of Biological Pathways Total Award* Amount: $2,031,725 Award Date: 09/21/12 Awarding Agency: National Human Genome Research Institute/NIH Principal Investigator: Derek Tan, PhD Project Title: Rational Design of Adenylation Enzyme Inhibitors Total Award* Amount: $316,182 Award Date: 09/13/12 Project Duration: 4 Years Awarding Agency: National Institute of General Medical Sciences Principal Investigator: Craig B. Thompson, MD Project Title: Cancer Center Support Grant Total Award* Amount: $27,191 Award Date: 09/14/12 Principal Investigator: Craig B. Thompson, MD Project Title: Cancer Center Support Grant Total Award* Amount: $41,006 Award Date: 09/14/12 Principal Investigator: Craig B. Thompson, MD Project Title: Cancer Center Support Grant 23 Memorial Sloan- Kettering Cancer Center

24 Total Award* Amount: $136,687 Award Date: 09/19/12 Principal Investigator: Ann Zauber, PhD Department/Program: Epidemiology & Biostatistics Project Title: Modeling Effective Health Policies for Colorectal Cancer Total Award* Amount: $2,973,095 Award Date: 09/20/12 August 2012 Principal Investigator: Samuel Danishefsky, PhD Project Title: Synthesis Directed Toward Therapeutic Agents Total Award* Amount: $1,280,003 Award Date: 08/30/12 Project Duration: 4 Years Awarding Agency: National Institute of General Medical Sciences Principal Investigator: Jenna Goldberg, MD Department/Program: Bone Marrow Transplant Service Project Title: Immune Mediated Disorders After Allogeneic Hematopoietic Cell Transplants (HCT) - Pilot 1 Total Award* Amount: $9,200 Award Date: 08/01/12 Awarding Agency: Fred Hutchinson Cancer Research Center/National Cancer Institute Principal Investigator: Eric Lai, PhD Department/Program: Developmental Biology Project Title: Non-Canonical mirna Biogenesis Mechanisms in Drosophila and Mammals Total Award* Amount: $1,053,281 Award Date: 08/30/12 Project Duration: 4 Years Awarding Agency: National Institute of General Medical Sciences Principal Investigator: Alexander Rudensky, PhD Department/Program: Immunology Project Title: Immunology Research Training Total Award* Amount: $1,107,912 Award Date: 08/01/12 24 Memorial Sloan- Kettering Cancer Center

25 INTERNAL COMPETITIONS Principal Investigator: Leila Akkari, PhD Project Title: Unraveling the Role of Cysteine Cathepsin Proteases in the Brain Tumor Microenvironment Total Award* Amount: $80,000 Award Date: 08/15/12 Awarding Agency: Brain Tumor Center 25 Memorial Sloan- Kettering Cancer Center

26 Principal Investigator: Robert Benezra, PhD Project Title: Neutrophil Mediated Anti-Metastatic Therapy Total Award* Amount: $352,000 Award Date: 08/10/12 Awarding Agency: Metastasis Research Center Research and Technology Management Principal Investigator: Christian Grommes, MD Department/Program: Neurology Project Title: Exploring the Role of the PI3(K) Pathway in Tumor Maintenance and Therapy Response in Primary CNS Lymphoma Total Award* Amount: $80,000 Award Date: 08/01/12 Awarding Agency: Brain Tumor Center Principal Investigator: Daniel Heller, PhD Project Title: Real-Time In Vivo Marker Detection for Rapid Measurement of Metastasis Onset Total Award* Amount: $400,000 Award Date: 08/10/12 Awarding Agency: Metastasis Research Center Principal Investigator: Johanna A. Joyce, PhD Project Title: Developing Novel Strategies to Target Tumor Cell-Macrophage Interactions in Brain Metastasis Total Award* Amount: $400,000 Award Date: 08/10/12 Awarding Agency: Metastasis Research Center Principal Investigator: Gary Mason, MD Department/Program: Human Oncology & Pathogenesis Program (HOPP) Project Title: Elucidating the Oncogenic Effects of Histone Protein Mutations in Pediatric Glioma Total Award* Amount: $80,000 Award Date: 08/15/12 Awarding Agency: Brain Tumor Center 26 Memorial Sloan- Kettering Cancer Center

27 Principal Investigator: Thomas Reiner, PhD Department/Program: Radiology Project Title: Novel Bioorthogonal Strategies for Glioblastoma-Targeted Peptidic PET Probes Total Award* Amount: $80,000 Award Date: 08/09/12 Awarding Agency: Brain Tumor Center Principal Investigator: Sriram Venneti, MD, PhD Project Title: Evaluation of Glutamine Metabolism in Gliomas Using Biochemical and In Vivo PET Imaging Approaches Total Award* Amount: $80,000 Award Date: 08/15/12 Awarding Agency: Brain Tumor Center Principal Investigator: Hans-Guido Wendel, MD Project Title: New Therapeutic Opportunities in Follicular Lymphoma Total Award* Amount: $400,000 Award Date: 08/01/12 Awarding Agency: Geoffrey Beene Cancer Research Center Principal Investigator: Alexandre Wojcinski, PhD Department/Program: Developmental Biology Project Title: Identification of Genes and Cell Behaviors Regulated by HH/GLI2 Signaling During Medulloblastomas Tumor Progression Total Award* Amount: $80,000 Award Date: 08/15/12 Awarding Agency: Brain Tumor Center Principal Investigator: Nancy Lee, MD Department/Program: Radiation Oncology Project Title: Hypoxia Image-Guided Radiation Therapy Total Award* Amount: $1,196,105 Award Date: 07/31/12 Principal Investigator: Timothy Chan, MD, PhD Department/Program: Radiation Oncology Project Title: P01 Interim Application 27 Memorial Sloan- Kettering Cancer Center

28 Total Award* Amount: $100,000 Award Date: 08/15/12 Awarding Agency: Brain Tumor Center Principal Investigator: Eric Holland, MD Department/Program: Neurosurgery/Departmental/Cancer Biology and Genetics Project Title: P01 Interim Application Total Award* Amount: $100,000 Award Date: 08/15/12 Awarding Agency: Brain Tumor Center Principal Investigator: Jason T. Huse, MD, PhD Department/Program: Human Oncology & Pathogenesis Program (HOPP) Project Title: P01 Interim Application Total Award* Amount: $64,000 Award Date: 08/15/12 Awarding Agency: Brain Tumor Center Principal Investigator: Johanna A. Joyce, PhD Project Title: P01 Interim Application Total Award* Amount: $100,000 Award Date: 08/15/12 Awarding Agency: Brain Tumor Center Principal Investigator: Tim A. Ahles, PhD Department/Program: Psychiatry/Neuropsychiatry Project Title: The CCNY/MSKCC Partnership for Research Training and Outreach Total Award* Amount: $4,546,069 Award Date: 09/20/12 Principal Investigator: Tim A. Ahles, PhD Department/Program: Psychiatry/Neuropsychiatry Project Title: The CCNY/MSKCC Partnership for Research Training and Outreach Total Award* Amount: $4,681,657 Award Date: 09/21/12 28 Memorial Sloan- Kettering Cancer Center

29 Principal Investigator: Zhirong Bao, PhD Department/Program: Developmental Biology Project Title: An Integrated System to Monitor Complex Tissues at Single-Cell Resolution Total Award* Amount: $2,281,856 Award Date: 09/26/12 Awarding Agency: National Institute of Child Health and Human Development Principal Investigator: Jonine Bernstein, PhD Department/Program: Epidemiology & Biostatistics Project Title: Mammographic Density and Risk of Contralateral Breast Cancer Total Award* Amount: $1,492,868 Award Date: 09/19/12 Principal Investigator: Luca Cartegni, PhD Project Title: Controlled Premature Termination of Translation to Generate Designated Truncated Variants Total Award* Amount: $413,250 Award Date: 09/20/12 Principal Investigator: Katharine C. Hsu, MD, PhD Department/Program: Bone Marrow Transplant Service Project Title: Phase 1 Study of Immunotherapy with NK Cells anti-gd2 for Neuroblastoma Total Award* Amount: $331,303 Award Date: 09/11/12 Awarding Agency: Food and Drug Administration Principal Investigator: David P. Kelsen, MD Department/Program: Medicine/Gastrointestinal Oncology Service Project Title: The Cancer Genome Atlas Gastroesophageal Cancers Total Award* Amount: $46,124 Award Date: 09/07/12 Awarding Agency: SAIC-Frederick/ National Cancer Institute Principal Investigator: Wendy G. Lichtenthal, PhD Department/Program: Psychiatry & Behavioral Sciences Project Title: Attention and Interpretation Modification for Fear of Breast Cancer Recurrence (AIM-FBCR): An Intervention Development Study 29 Memorial Sloan- Kettering Cancer Center

30 Total Award* Amount: $90,000 Award Date: 09/12/12 Awarding Agency: Clinical and Translational Science Center/National Center for Research Resources Principal Investigator: Ingo K. Mellinghoff, MD Department/Program: Neurology/Neurology Service Project Title: Molecular Mechanisms of IDH1-mediated Gliomagenesis Total Award* Amount: $1,194,094 Award Date: 09/20/12 Awarding Agency: National Institute of Neurological Disorders and Stroke October 2012 Principal Investigator: Dean F. Bajorin, MD Department/Program: Medicine/Genitourinary Oncology Service Project Title: K30 Research Education Total Award* Amount: $1,291,005 Award Date: 10/23/12 Awarding Agency: Clinical and Translational Science Center/National Center for Research Resources Principal Investigator: Richard D. Carvajal, MD Department/Program: Medicine/Melanoma & Sarcoma Service Project Title: Participant and Clinical Interaction Resources Total Award* Amount: $904,235 Award Date: 10/23/12 Awarding Agency: Clinical and Translational Science Center/National Center for Research Resources Principal Investigator: Nai-Kong Cheung, MD, PhD Department/Program: Pediatrics Project Title: Phase I Study of Humanized 3F8 Monoclonal Antibody (Hu3F8) in Patients with High-Risk Neuoblastoma and GD2-Positive Tumors Total Award* Amount: $1,477,221 Award Date: 10/02/12 Awarding Agency: Congressionally Directed Medical Research Programs Principal Investigator: Katherine Fain, MPA Department/Program: Clinical Research 30 Memorial Sloan- Kettering Cancer Center

31 Project Title: Regulatory Knowledge and Support Total Award* Amount: $165,995 Award Date: 10/23/12 Awarding Agency: Clinical and Translational Science Center/National Center for Research Resources Principal Investigator: Alberto Fernandez-Tejada, PhD Project Title: Vaccine Adjuvants Total Award* Amount: $24, Award Date: 10/14/12 Awarding Agency: European Union Principal Investigator: Alan L. Ho, MD, PhD Department/Program: Medicine/Head and Neck Oncology Project Title: Targeting the Oncogenic Transcription Factor c-myb in Adenoid Cystic Carcinomas Total Award* Amount: $622,500 Award Date: 10/03/12 Principal Investigator: Eric Holland, MD Department/Program: Neurosurgery/Departmental/Cancer Biology and Genetics Project Title: Non-neoplastic cell types dictate gliomagenesis and response to therapy Total Award* Amount: $324,055 Award Date: 10/15/12 Awarding Agency: Cleveland Clinic Foundation/National Cancer Institute Principal Investigator: Raya Khanin, PhD Department/Program: Research Facilities Project Title: Bioinformatics Total Award* Amount: $1,232,775 Award Date: 10/23/12 Awarding Agency: Clinical and Translational Science Center/National Center for Research Resources Principal Investigator: Michael LaQuaglia, MD Department/Program: Pediatric Surgical Service Project Title: Children's Oncology Group: Scientific Leadership Chair Grant Total Award* Amount: $11, Memorial Sloan- Kettering Cancer Center

32 Award Date: 10/17/12 Awarding Agency: Children's Hospital of Philadelphia/National Cancer Institute Principal Investigator: Douglas A. Levine, MD Department/Program: Surgery/Gynecology Service Project Title: PROTOCOL GOG-0229N: Phase II Evaluation of ACE-041 Total Award* Amount: $118,009 Award Date: 10/17/12 Awarding Agency: Gynecological Oncology Group Principal Investigator: Douglas A. Levine, MD Department/Program: Surgery/Gynecology Service Project Title: The Cancer Genome Atlas: Retrospective Cases of Uterine Carcinosarcoma Total Award* Amount: $122,560 Award Date: 10/05/12 Awarding Agency: SAIC-Frederick/National Cancer Institute Principal Investigator: Babak J. Mehrara, MD Department/Program: Surgery/Plastic and Reconstructive Surgical Service Project Title: Mechanisms of Fibrosis and Lymphatic Dysfunction in Post-Surgical Lymphedema Total Award* Amount: $2,141,093 Award Date: 10/05/12 Awarding Agency: National Heart, Lung, and Blood Institute Principal Investigator: Dinshaw J. Patel, PhD Department/Program: Structural Biology Project Title: Chromatin Mechanisms and Epigenetic Targeting in Hematological Malignancies Total Award* Amount: $750,000 Award Date: 10/18/12 Awarding Agency: Northwestern University/Leukemia and Lymphoma Society Principal Investigator: George Plitas, MD Department/Program: Surgery Project Title: Impact of Regulatory T cells on the tumor microenvironment during breast carcinogenesis Total Award* Amount: $47,500 Award Date: 10/10/12 32 Memorial Sloan- Kettering Cancer Center

33 Awarding Agency: Conquer Cancer Foundation of the American Society of Clinical Oncology Principal Investigator: Milind Rajadhyaksha, PhD Department/Program: Medicine/Dermatology Project Title: Line-scanned MEMS-based dual-axes confocal microscopy to detect oral lesions in vivo Total Award* Amount: $785,190 Award Date: 10/18/12 Awarding Agency: Stony Brook University/National Institute of Dental and Craniofacial Research Principal Investigator: Jaya Satagopan, PhD Department/Program: Epidemiology & Biostatistics Project Title: Research Design and Biostatistics Total Award* Amount: $326,240 Award Date: 10/24/12 Awarding Agency: Clinical and Translational Science Center/National Center for Research Resources Principal Investigator: Yiauchung Sheh, MS Project Title: Translational Technologies and Resources Total Award* Amount: $99,825 Award Date: 10/18/12 Awarding Agency: Clinical and Translational Science Center/National Center for Research Resources Principal Investigator: Hans-Guido Wendel, MD Project Title: Improving Treatment of Follicular Lymphoma Total Award* Amount: $600,000 Award Date: 10/01/12 Awarding Agency: American Cancer Society Principal Investigator: Richard White, MD, PhD Project Title: BRAFV600E as a Regulator of Transcriptional Elongation Total Award* Amount: $50,000 Award Date: 10/23/12 33 Memorial Sloan- Kettering Cancer Center

34 Awarding Agency: American Association for Cancer Research Research and Technology Management Principal Investigator: Haiming Xu, PhD Department/Program: Human Oncology & Pathogenesis Program (HOPP) Project Title: Molecular Mechanism of Severe Cytopenia in a Mouse Model of Myelodysplastic Syndromes (MDS) Total Award* Amount: $299,954 Award Date: 10/17/12 Project Duration: Years Awarding Agency: Congressionally Directed Medical Research Programs November 2012 Principal Investigator: Katherine M. Bell-McGuinn, MD, PhD Department/Program: Medicine/Gynecologic Medical Oncology Project Title: Targeting the P13K Pathway in Women s Cancers Total Award* Amount: $58,035 Award Date: 11/02/12 Awarding Agency: Dana Farber Cancer Institute/Stand Up To Cancer Principal Investigator: Francesca Gany, MD Department/Program: Psychiatry & Behavioral Sciences Project Title: Assessing the Contribution of Transplantation Barriers to Disparities in Liver Cancer Survival in Minorities Total Award* Amount: $13,390 Award Date: 11/07/12 Awarding Agency: Mount Sinai School of Medicine/National Cancer Institute Principal Investigator: Francesca Gany, MD Department/Program: Psychiatry & Behavioral Sciences Project Title: The Taxi Network Total Award* Amount: $561,200 Award Date: 11/20/12 Awarding Agency: National Center on Minority Health and Health Disparities Principal Investigator: Richard N. Kolesnick, MD Department/Program: Medicine/Endocrinology/Molecular Pharmacology & Chemistry Project Title: Neutralization of Ceramide as a Novel Approach to Specifically Inhibit Acute GVHD Total Award* Amount: $93,976 Award Date: 11/12/12 34 Memorial Sloan- Kettering Cancer Center

35 Awarding Agency: Ceramide Therapeutics, LLC/National Institute of Allergy and Infectious Diseases Principal Investigator: Douglas A. Levine, MD Department/Program: Surgery/Gynecology Project Title: Proteome Characterization Center: A Genoproteomics Pipeline for Cancer (Verification Unit) Total Award* Amount: $15,252 Award Date: 11/03/12 Awarding Agency: Johns Hopkins University/National Cancer Institute Principal Investigator: Scott Lowe, PhD Project Title: Cold Spring Harbor Laboratory Cancer Research Center Total Award* Amount: $1,852,040 Award Date: 11/02/12 Project Duration: 4 Years Awarding Agency: Cold Spring Harbor Laboratory/National Cancer Institute Principal Investigator: Jamie Ostroff, PhD Department/Program: Psychiatry Project Title: Integrating Tobacco Treatment Into Cancer Care Total Award* Amount: $705,870 Award Date: 11/14/12 Awarding Agency: Massachusetts General Hospital/National Cancer Institute Principal Investigator: Si Jia Pan, PhD Project Title: Identification of Notch-1 and Notch-2 Modulators for Tumor Therapies Total Award* Amount: $45,941 Award Date: 11/07/12 Awarding Agency: Weill Medical College of Cornell University/National Cancer Institute Principal Investigator: Dinshaw J. Patel, PhD Department/Program: Structural Biology Project Title: Posttranscriptional Regulation by mrna-binding Shuttling and Transport Proteins Total Award* Amount: $832,500 Award Date: 11/14/12 Awarding Agency: Rockefeller University/National Institutes of Health 35 Memorial Sloan- Kettering Cancer Center

36 October 2012 Principal Investigator: Michelle S. Bradbury, MD, PhD Department/Program: Radiology/Neuroradiology Project Title: Renally Excreted Multimodal Silica Nanoparticles as Melanoma-Selective Therapies Total Award* Amount: $70,000 Award Date: 10/18/12 Awarding Agency: Clinical and Translational Science Center/National Center for Research Resources Principal Investigator: Samuel Danishefsky, PhD Project Title: Construction of Glycopeptide Immunogens Total Award* Amount: $106,902 Award Date: 10/19/12 Awarding Agency: Duke University Medical Center/National Institute of Allergy and Infectious Diseases Principal Investigator: Mark Frattini, MD, PhD Department/Program: Medicine/Leukemia Project Title: Genome-Wide Identification of DNA Methylation Biomarkers in AML Total Award* Amount: $19,112 Award Date: 10/16/12 Awarding Agency: Cornell University/National Institutes of Health Principal Investigator: Mark Kris, MD Department/Program: Medicine/Thoracic Oncology Project Title: Lung Cancer Mutation Consortium (LCMC) Total Award* Amount: $75,000 Award Date: 10/18/12 Awarding Agency: National Lung Cancer Partnership/University of Colorado at Denver Principal Investigator: Douglas A. Levine, MD Department/Program: Surgery/Gynecology Project Title: PROTOCOL GOG-0170R, A Phase II Evaluation of Dalantercept Total Award* Amount: $118,009 Award Date: 10/24/12 Awarding Agency: Gynecological Oncology Group 36 Memorial Sloan- Kettering Cancer Center