Curriculum Vitae. NET-JRF and Eligibility for Lectureship (June 1999): (Life Sciences) conducted By CSIR-UGC

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1 Curriculum Vitae A). Personal Details Name: Dr. Praveen Kumar Sharma Present Address: Centre of Life science, School of Natural sciences Central University of Jharkhand Brambe, Ranchi, Jharkhand Date of Birth: 25 th March, 1977 Gender: Male Nationality: INDIAN E mail: pksharma@cuj.ac.in B) Academic: Ph.D. (Jan 2000 to Dec. 2005): Title of thesis: Expression and regulation of Estrogen receptors in cerebral cortex of Aging Mouse. Supervisor: Prof. M. K. Thakur, Biochemistry and Molecular Biology Unit, Centre for Advance Study, Department of Zoology, Banaras Hindu University, Varanasi, Uttar Pradesh, India. NET-JRF and Eligibility for Lectureship (June 1999): (Life Sciences) conducted By CSIR-UGC M.Sc. ( ): Zoology (Specialization in Molecular Biology and Metabolism, Centre for Advance Study, Department of Zoology, Banaras Hindu University, Varanasi, Uttar Pradesh, India. B.Sc. ( ): K.B. P.G. College, Mirzapur (Then under V.B.S. Purvanchal University, Jaunpur. Uttar Pradesh, India. C) Area of Specialization: Molecular Biology, Neurobiology, Cell Signaling, Cancer Biology D) Academic ID ORCID Id: Researcher Id: L Google Scholar Id: OrbRTfwAAAAJ Vidwan Expert Id: E) Work Experience: Post-Doctoral Research: James Graham Brown Cancer Centre, University of Louisville, Louisville, KY, USA. Teaching Experience: Assistant Professor (contract) Centre for Life Sciences, Central University of Jharkhand Assistant Professor (Regular) Centre for Life Sciences, Central University of Jharkhand Administrative: Present: Coordinator NSS, Central University of Jharkhand

2 Member Proctorial Board, Central University of Jharkhand Past: Administrative Warden, Boy s hostel, Central University of Jharkhand F) Membership of Professional Organization: Present: Life Member, Indian academy of Neuroscience Life member, Association of Gerontology, India International Brain Research Organization Past: American association of Immunologists (AAI) American Association of Cancer Research (AACR) G) Research Publications: Peer Reviewed Original Research Papers 1: Gupta P, Sharma PK, Mir H, Singh R, Singh N, Kloecker GH, Lillard JW Jr, Singh S.(2014). CCR9/CCL25 expression in non-small cell lung cancer correlates with aggressive disease and mediates key steps of metastasis. Oncotarget Sep 25. [Epub ahead of print] 2: Rajesh Singh, Pranav Gupta,Praveen Kumar Sharma,Edwin W. Ades, Susan K. Hollingshead, Shailesh Singh, James W. Lillard Jr. (2014). Prediction and Characterization of helper T cell epitopes from pneumococcal surface adhesin A (PsaA). Immunology 141(4). DOI: /imm : Christelle P El-Haibi, Praveen Sharma, Rajesh Singh, Pranav Gupta, Dennis D Taub, Shailesh Singh, James W Lillard (2013) Differential G protein subunit expression by prostate cancer cells and their interaction with CXCR5. Molecular Cancer. 12(1):64. DOI: / : El-Haibi CP, Singh R, Gupta P, Sharma PK, Greenleaf KN, Singh S, Lillard JW Jr. (2012) Antibody microarray analysis of signaling networks regulated by Cxcl13 and Cxcr5 in prostate cancer. J. Proteomics Bioinform.5(8): doi: /jpb : El-Haibi CP, Singh R, Sharma PK, Singh S, Lillard JW Jr. (2011) CXCL13 mediates prostate cancer cell proliferation through JNK signaling and invasion through ERK activation. Cell Prolif. 44(4): : Christelle P El Haibi, Praveen K Sharma, Rajesh Singh, Paul R Johnson, Jill Suttles, Shailesh Singh and James W Lillard Jr. (2010) PI3Kp110-, Src-, FAK- dependent and DOCK2-independent migration and invasion of CXCL13-stimulated prostate cancer Cells. Molecular Cancer, 9:85 7: Rajesh Singh, Shailesh Singh, Praveen K Sharma, Udai P Singh, David E. Briles, Susan K. Hollingshead, James W. Lillard, Jr (2010) Helper T Cell Epitope- mapping reveals MHC-Peptide binding affinities that correlate with T helper cell responses to Pneumococcal Surface Protein A. PLos One 5:e9432

3 8: Sharma PK, Singh R, Eaton J, Novakovic KR, Chun LWK, Grizzle WE, Singh S (2010). CCR9- CCL25 interaction inhibits drug induced apoptosis of prostate cancer cell. Int. J. Cancer. 127 (9); : Singh S, Singh R, Sharma PK, Singh UP, Rai SN, Chung LWK, Cooper CR, Novakovic KR, Grizzle WE, Lillard JW Jr (2009). Serum CXCL13 positively correlated with prostatic disease, prostate specific antigen and mediates prostate cancer cell invasion, integrin clustering and cell adhesion. Cancer Lett. 283: : Thakur MK, Sharma PK (2008) Binding of Estrogen receptor alpha promoter to nuclear proteins of mouse cerebral cortex; effect of age, sex and gonadal steroids. Biogerontol 9: : Thakur MK, Sharma PK (2007) Transcription of estrogen receptor and β in mouse cerebral cortex: effect of age, sex, 17 β estradiol and testosterone. Neurochem Int 50: : Sharma PK, Thakur MK (2006) Expression of estrogen receptor (ER) and β in mouse cerebral cortex: effect of age, sex, and gonadal steroids. Neurobiol. Aging 27: : Gaur P, Thakur BK, Sharma PK, Oka T, Thakur MK (2005). Expression of perchloric acid soluble 14 kda protein in mouse brain. Anal. Neurosci. 12: : Sharma PK, Thakur MK (2004). Estrogen receptor α expression in mice kidney shows sex differences during aging. Biogerontol 5: : Thakur MK, Sharma PK, Ghosh S, Mani ST (2004). Estrogen intervention in aging and longevity: problems and perspectives. Geriat. Gerontol Int 6: S259-S261. Peer Reviewed Review: 1: Thakur MK, Sharma PK (2006). Aging of Brain: Role of Estrogen. Neurochem. Res. 31: Book Chapter: 1: Thakur MK, Sharma PK, Ghosh S. (2005) Estrogen effects in the brain: Implications for aging and Alzheimer s disease. In Molecular and Cellular Neurobiology (eds. MK Thakur and S Prasad), Narosa Publishing House Pvt. Ltd., New Delhi. Pp Selected Abstracts Published in conference Proceedings 1: CXCR6-CXCL16 interaction in prostate cancer cells activate signaling molecules involved in cytoskeletal rearrangement. NEHU, Shillong.25/03/2011 2: Sharma PK, Singh R, Eaton JW, Lillard JW Jr., Novakovic KR, Grizzle WE, Chung LWK & Singh S. CCL25 blockade inhibits anti-apoptotic signals in prostate cancer cells and enhances the efficacy of etoposide. American Urological Association (AUA) Annual meeting Abs# : Singh R, Singh S, Sharma PK & Lillard JW Jr. XPCLAD nanoparticle-mediated prostate tumor and T-regulatory cell targeting and apoptosis. AUA Abs#

4 4: Lasharon D. Mosley,Rajesh Singh, Praveen K. Sharma, Ashley S. Triplett1, Shailesh Singh, James W. Lillard, Jr.. Mechanisms mediated by CXCL12 signaling through CXCR4 and CXCR7 in breast cancer. AACR Annual Meeting Abs # : Praveen K. Sharma, Rajesh Singh, William E. Grizzle, Shailesh Singh, Clinical and biological significance of CCR9-CCL25 axis in prostate cancer. AACR Annual Meeting Abs# : Ashley Triplet,Praveen K. Sharma, Rajesh Singh, James W. Lillard, Jr., William E. Grizle, Shailesh Singh CXCR6-mediated cellular and molecular events involved in breast cancer cell migration and invasion. AACR Annual Meeting Abs# : Triplett Ashley,Sharma Praveen,Singh Rajesh, Lillard James,Singh Shailesh CXCR6 mediates migration and invasion of breast cancer cells in a Src, FAK, and ERK1/2 dependent fashion. J Immunol V 184, AAI Annual meeting abstarcts : Lillard James, Singh Rajesh, Sharma Praveen, Singh Shailesh CXCL13 inhibition prevents bone metastasis in hormone-refractory prostate cancer. J Immunol V AAI Annual meeting abstarcts. 9: Singh Shailesh, Sharma Praveen, Singh Rajesh, Grizzle William, Role of CCR9-CCL25 axis in Prostate Cancer Metastasis. J Immunol V AAI Annual meeting abstarcts. 10: Sharma PK, Singh R, Eaton JW, Lillard JW Jr., Novakovic KR, Grizzle WE, Chung LWK & Singh S. CCL25 blockade inhibits anti-apoptotic signals in prostate cancer cells and enhances cytotoxic effects of Etoposide. AACR Annual Meeting Abs# : Sharma PK, Singh R, Eaton JW, Lillard JW Jr., Novakovic KR, Grizzle WE, Chung LWK & Singh S. Expression and functional role of CXCR6 in prostate cancer. AACR Annual Meeting Abs# : Singh R, Singh S, Sharma PK & Lillard JW Jr. Prostate cancer cell- and T regulatory cell-specific drug targeting using novel XPclad nanoparticles. AACR Annual Meeting Abs.# : Mosley LD, Sharma P, Singh R, Singh S & Lillard JW Jr. CXCL11 and CXCL12 modulates matrix metalloproteinase expression by breast cancer cells predominately through CXCR7 interactions. AACR Annual Meeting Abs# : El-Haibi CP, Johnson PR, Sharma P, Suttles J, Singh S & Lillard JW Jr. CXCL13-CXCR5 interactions support prostate cancer cell migration and invasion in a PI3K p110-, SRC-, and FAKdependent. AACR Annual Meeting Abs# : Mosley LD, Singh R, Sharma PK, Singh S & Lillard JW Jr. CXCL11 and CXCL12 modulate ERK1/2 and NF-kB activation in breast cancer cells via CXCR3, CXCR4 and CXCR7. AACR Annual Meeting Abs# : El-Haibi C, Singh R, Sharma PK, Singh S & Lillard JW Jr. CXCL13 blockade abrogates bone metastasis by impairing integrinβ3 activation and matrix metalloproteinase expression by prostate cancer cells. AACR Annual Meeting Abs#

5 17: Sharma PK, Singh R, Eaton JW, Lillard JJW Jr., Novakovic KR, Grizzle WE & Singh S. Inhibition of anti-apoptotic signals in prostate cancer cells by CCL25 blockade enhances the cytotoxic effects of etoposide. J Immunol, 2009, 182 (MeetingAbstracts), 98:91. 18: Singh R, Singh S, Sharma PK & Lillard JJW Jr. T regulatory and prostate cancer cell-specific drug targeting using novel XPclad (C) nanoparticles. J Immunol, 2009, 182 (MeetingAbstracts), 42:47. 19: El-Haibi CP, Johnson PR, Sharma PK, Suttles J, Singh S & Lillard JJW Jr. CXCL13-CXCR5 interactions support prostate cancer cell migration and invasion in a PI3K p110-, SRC- and FAKdependent fashion. J Immunol, 2009, 182 (MeetingAbstracts), 98:95. 20: El-Haibi CP, Singh R, Sharma PK, Singh S & Lillard JJW Jr. CXCL13 blockade abrogates bone metastasis by impairing beta-3 integrin activation and matrix metalloproteinase expression by prostate cancer cells. J Immunol, 2009, 182 (MeetingAbstracts), 98:94. 21: Mosley LD, Sharma PK, Singh R, Singh S & Lillard JJW Jr. CXCL11 and CXCL12 mediate matrix metalloproteinase expression by breast cancer cells through CXCR7. J Immunol, 2009, 182 (MeetingAbstracts). 98:92. 22: Mosley LD, Singh R, Sharma PK, Singh S & Lillard JJW Jr. CXCL11 and CXCL12 activates ERK1/2 and NF-kB in breast cancer cells via CXCR3, CXCR4 and CXCR7. J Immunol, 2009, 182 (MeetingAbstracts), 98:93. 23: Sharma P, Singh R, Lillard J, Chung L, Grizzle W & Singh S. CCR9-mediated inhibition of druginduced apoptosis in prostate cancer cells. AACR Annual meeting Abstarct # : Singh R, Sharma P, Singh S & Lillard J. Cisplatin- loaded starch nanoparticle enhance the efficacy of chemotherapy in prostate cancer. AACR Annual meeting Abstarct # : El-Haibi C, Singh S, Sharma P & Lillard J. Identification of G protein isoforms coupled to CXCR5 in prostate cancer cells. AACR Annual meeting Abstarct # : Mosley L, Sharma P, Singh R, Singh S, & Lillard J. CXCR7 and CXCR3 interactions promote breast cancer (BrCa) cell migration, adhesion and survival. AACR Annual meeting Abstarct # : Sharma PK, Singh R, Lillard JW Jr, Chung LWK, Grizzle WE, Singh S (2008). Anti apoptotic role of CCR9 in prostate cancer. FASEB 22: : Mosley LD, Sharma PK, Singh R, Singh S, Lillard JW Jr (2008). Differential beta-3 integrin of CXCR3, CXCR4, and CXCR7 clustering on breast cancer cells in response to CXCL11, CXCL12, and Adrenomedullin. FASEB 22: *******************************