Supplement: Table 1 List of analyzed metabolites Acylcarnitines (41)
|
|
|
- Christian Grant
- 6 years ago
- Views:
Transcription
1 Supplement: Table 1 List of analyzed metabolites Acylcarnitines (41) C0 Carnitine C2 Acetylcarnitine C3 Propionylcarnitine C3:1 Propenoylcarnitine semi- C3-OH Hydroxypropionylcarnitine semi- C4 Butyrylcarnitine / Isobutyrylcarnitine C4:1 Butenoylcarnitine semi- C4-OH (C3-DC) Hydroxybutyrylcarnitine (Malonylcarnitine) semi- C5 Valerylcarnitine / Isovalerylcarnitine / Methylbutyrylcarnitine C5:1 Tiglylcarnitine / Methylcrotonylcarnitine semi- C5:1-DC Glutaconylcarnitine / Mesaconylcarnitine semi- C5-DC (C6-OH) Glutarylcarnitine (Hydroxyhexanoylcarnitine) semi- C5-M-DC Methylglutarylcarnitine semi- C5-OH (C3-DC-M) Hydroxyvaleryl- / -isovaleryl- / -methylbutyrylcarnitine (Methylmalonylcarnitine) semi- C6 (C4:1-DC) Hexanoylcarnitine (Fumarylcarnitine) semi- C6:1 Hexenoylcarnitine semi- C7-DC Pimelylcarnitine semi- C8 Octanoylcarnitine C8:1 Octenoylcarnitine semi- C9 Nonanoylcarnitine semi- C10 Decanoylcarnitine C10:1 Decenoylcarnitine semi- C10:2 Decadienylcarnitine semi- C12 Dodecanoylcarnitine C12:1 Dodecenoylcarnitine semi- C12-DC Dodecanedioylcarnitine semi- C14 Tetradecanoylcarnitine C14:1 Tetradecenoylcarnitine semi- C14:1-OH Hydroxytetradecenoylcarnitine semi- C14:2 Tetradecadienylcarnitine semi- C14:2-OH Hydroxytetradecadienylcarnitine semi- C16 Hexadecanoylcarnitine C16:1 Hexadecenoylcarnitine semi- C16:1-OH Hydroxyhexadecenoylcarnitine semi- C16:2 Hexadecadienylcarnitine semi- C16:2-OH Hydroxyhexadecadienylcarnitine semi- C16-OH Hydroxyhexadecanoylcarnitine semi- C18 Octadecanoylcarnitine C18:1 Octadecenoylcarnitine semi- C18:1-OH Hydroxyoctadecenoylcarnitine semi- C18:2 Octadecadienylcarnitine semi- 1
2 Amino acids (21) Bile acids (17) Alanine Cholic acid Arginine Chenodeoxycholic acid Asparagine Deoxycholic acid Aspartic acid Glycocholic acid Citrulline Glycochenodeoxycholic acid Glutamine Glycodeoxycholic acid Glutamic acid Glycolithocholic acid Glycine Glycolithocholic acid sulfate Histidine Glycoursodeoxycholic acid Isoleucine Lithocholic acid Leucine Taurocholic acid Lysine semi- Taurochenodeoxycholic acid Methionine Taurodeoxycholic acid Ornithine Taurolithocholic acid Phenylalanine Taurolithocholic acid sulfate Proline Tauroursodeoxycholic acid Serine Ursodeoxycholic acid Threonine Tryptophan Eicosanoids and other Oxidation Products of Polyunsaturated Fatty acids (PUFA s)* (17) Tyrosine Leukotriene B4 Valine Thromboxane B2 Leukotriene D4 Biogenic Amines and Polyamines (14) Prostaglandin E2 Asymmetric dimethylarginine 8-iso-Prostaglandin F2α Symmetric dimethylarginine Prostaglandin F2α Total dimethylarginine 6-keto-Prostaglandin F1α Histamine Prostaglandin D2 Methionine-sulfoxide 9S-HODE Kynurenine 13S-HODE Hydroxykynurenine 14(15)-EpETE Putrescine 12S-HETE Spermidine semi- 15S-HETE Spermine semi- 15S-HpETE Serotonin semi- 5S-HpETE Phenylethylamine Arachidonic acid Nitrotyrosine Docosahexaenoic acid Creatinine Energy Metabolism (17) 3-Phosphoglycerate α-ketoglutaric acid Adenosine-5'-monophosphate Arginine Aspartate 3'-5'-cyclic Adenosine monophosphate Dihydroxyacetonephosphate + 3-Phosphoglyceraldehyde 2 semi- semi- semi- semi-
3 Fumarate Glutamate Hexose (e.g. Glucose) Hexosephosphate (e.g. Glucose-1-phosphate + Glucose-6-phosphate + Fructose-6-phosphate) Lactate Pentosephosphate (e.g. Ribose-5-phosphate + Ribulose-5-phosphate) Phosphoenolpyruvate Pyruvate + Oxaloacetate Succinate Tetrosephosphate (e.g. Erythrose-4-phosphate) semi- semi- semi- Glycerophospholipids* (92) PC aa C24:0 semi- PC ae C34:3 semi- PC aa C26:0 semi- PC ae C36:0 semi- PC aa C28:1 semi- PC ae C36:1 semi- PC aa C30:0 semi- PC ae C36:2 semi- PC aa C30:2 semi- PC ae C36:3 semi- PC aa C32:0 semi- PC ae C36:4 semi- PC aa C32:1 semi- PC ae C36:5 semi- PC aa C32:2 semi- PC ae C38:0 semi- PC aa C32:3 semi- PC ae C38:1 semi- PC aa C34:1 semi- PC ae C38:2 semi- PC aa C34:2 semi- PC ae C38:3 semi- PC aa C34:3 semi- PC ae C38:4 semi- PC aa C34:4 semi- PC ae C38:5 semi- PC aa C36:0 semi- PC ae C38:6 semi- PC aa C36:1 semi- PC ae C40:0 semi- PC aa C36:2 semi- PC ae C40:1 semi- PC aa C36:3 semi- PC ae C40:2 semi- PC aa C36:4 semi- PC ae C40:3 semi- PC aa C36:5 semi- PC ae C40:4 semi- PC aa C36:6 semi- PC ae C40:5 semi- PC aa C38:0 semi- PC ae C40:6 semi- PC aa C38:1 semi- PC ae C42:0 semi- PC aa C38:3 semi- PC ae C42:1 semi- PC aa C38:4 semi- PC ae C42:2 semi- PC aa C38:5 semi- PC ae C42:3 semi- PC aa C38:6 semi- PC ae C42:4 semi- PC aa C40:1 semi- PC ae C42:5 semi- PC aa C40:2 semi- PC ae C44:3 semi- PC aa C40:3 semi- PC ae C44:4 semi- PC aa C40:4 semi- PC ae C44:5 semi- PC aa C40:5 semi- PC ae C44:6 semi- PC aa C40:6 semi- lysopc a C6:0 semi- PC aa C42:0 semi- lysopc a C14:0 semi- PC aa C42:1 semi- lysopc a C16:0 semi- PC aa C42:2 semi- lysopc a C16:1 semi- 3
4 PC aa C42:4 semi- lysopc a C17:0 semi- PC aa C42:5 semi- lysopc a C18:0 semi- PC aa C42:6 semi- lysopc a C18:1 semi- PC ae C30:0 semi- lysopc a C18:2 semi- PC ae C30:1 semi- lysopc a C20:3 semi- PC ae C30:2 semi- lysopc a C20:4 semi- PC ae C32:1 semi- lysopc a C24:0 semi- PC ae C32:2 semi- lysopc a C26:0 semi- PC ae C34:0 semi- lysopc a C26:1 semi- PC ae C34:1 semi- lysopc a C28:0 semi- PC ae C34:2 semi- lysopc a C28:1 semi- Oxysterols (16) 22-R-Hydroxycholesterol 24-S-Hydroxycholesterol 25-Hydroxycholesterol 27-Hydroxycholesterol 22S-Hydroxycholesterol 24,25-Epoxycholesterol 7α-Hydroxycholesterol 7-Ketocholesterol 5ß,6ß-Epoxycholesterol 5α,6α-Epoxycholesterol 4ß-Hydroxycholesterol Desmosterol 7-Dehydrocholesterol Cholestenone Lanosterol 24-Dihydrolanosterol semi- Sphingolipids (Sphingomyelins)* (15) SM (OH) C14:1 SM C16:0 SM C16:1 SM (OH) C16:1 SM C18:0 SM C18:1 SM C20:2 SM C22:3 SM (OH) C22:1 SM (OH) C22:2 SM C24:0 SM C24:1 SM (OH) C24:1 SM C26:0 SM C26:1 semi- semi- semi- semi- semi- semi- semi- semi- semi- semi- semi- semi- semi- semi- semi- *) validated analytical method (FDA guidance for industry) 4
5 Analysed ratio`s Definition Numerator Denominator Orn/Cit Ornithine Citrulline Orn/Arg Ornithine Arginine Cit/Arg Citrulline Arginine Glu/Gln Glutamate Glutamine Asp/Asn Aspartic acid Asparagine Ala/Lys Alanine Lysine Phe/Tyr Phenylalanine Tyrosine Serotonin/Trp Serotonin Tryptophane Kyn/Trp Kynurenine Tryptophane Kyn/OHKyn Kynurenine Hydroykynurenine Putrescine/Orn Putrescine Ornithine Spermine/Spermidine Spermine Spermidine SDMA/ADMA Symmetric dimethylarginine Asymmetric dimethylarginine Met-SO/Met Methionine-Sulfoxide Methionine Ala/BCAA Alanine G.M. of Valine, Isoleucine and Leucine Gly/BCAA Glycine G.M. of Valine, Isoleucine and Leucine SumLyso SumPC+Lyso SumPC SumSM G.M. of 15 LysoPC G.M. of 92 LysoPC and PC G.M. of 77 PC G.M. of 15 SM SumSMOH/SumSM G.M. of 5 SM(OH) G.M. of 10 SM C16+C18/C0 G.M. of palmitoylcarnitine and stearylcarnitine Carnitine (free) SumMUFA G.M. of 26 mono-unsaturated lipids SumPUFA G.M. of 82 poly-unsaturated lipids SumSFA G.M. of 25 saturated lipids PUFA/SFA G.M. of 82 poly-unsaturated lipids G.M. of 25 saturated lipids PUFA/MUFA G.M. of 82 poly-unsaturated lipids G.M. of 26 mono-unsaturated lipids MUFA/SFA G.M. of 26 mono-unsaturated lipids G.M. of 25 saturated lipids 5
List of Metabolites: MxP Quant 500 Kit
List of Metabolites: MxP Quant 500 Kit Trigonelline TMAO Trigonelline Trimethylamine N-oxide Alkaloids (1) Amine Oxides (1) Amino Acids (20) Ala Alanine Leu Leucine Arg Arginine Lys Lysine Asn Asparagine
The choice is yours. Biocrates offers the technology to detect and quantify over 600 metabolites
List of Metabolites We provide the Phenotype to the Genotype! Metabolite menu Docr. 35006 V 4.0 2017-01 The choice is yours. Biocrates offers the technology to detect and quantify over 600 metabolites
ACYLCARNITINES, QUANTITATIVE, PLASMA
Lab Dept: Test Name: Chemistry ACYLCARNITINES, QUANTITATIVE, PLASMA General Information Lab Order Codes: ACYP Synonyms: CPT Codes: Test Includes: Glycine conjugates plasma 82017 Acylcarnitines, quantitative,
Annotation of potential isobaric and isomeric lipid species analyzed using the MxP Quant 500 Kit
Annotation of potential isobaric and isomeric lipid species analyzed using the MxP Quant 500 Kit Introduction The MxP Quant 500 kit enables the analysis of up to 630 metabolites covering 26 compound classes
Newborn screening panel by American Health Information Community (AHIC)
Page 1 of 5 54089-8 Newborn screening panel by American Health Information Community (AHIC) NAME Component Property Time System Scale Method Example Units Newborn screening panel - Pt ^Patient - AHIC BASIC
Stable Isotope Standards for Mass Spectrometry
Cambridge Isotope Laboratories, Inc. isotope.com Stable Isotope Standards for Mass Spectrometry Mass spectrometry (MS) used as a routine tool in the clinic is becoming more and more of a reality every
Amino Acid Analyzer AAA400
Amino Acid Analyzer AAA400 Determination of amino acid of hydrolyzates (food and feed) Column: LG ANB OSTION 3.6x340 12μm Eluents: sodium-citrate buffers, 0.2 M NaOH Aspartic Acid, Threonine, Serine, Glutamic
TARGETED METABOLOMICS
[ APPLICATION NOTEBOOK ] TARGETED METABOLOMICS AND LIPIDOMICS This notebook is an excerpt from the larger Waters Application Notebook on Metabolomics and Lipidomics #720005245EN TABLE OF CONTENTS 3 Introduction
MRC-NIHR NPC Assay Portfolio
MRC-NIHR NPC Assay Portfolio No one technology platform or assay can provide the comprehensive coverage of the metabolome needed to provide insight into complex biological processes which is why the MRC-NIHR
Age-related reference ranges
Authoriser: Peter Beresford Page 1 of 6 Age-related reference ranges Alkaline Phosphatase (ALP) IU/L Both less than 14 days 90 273 Both 14 days
FRAMINGHAM HEART STUDY CODING MANUAL Metabolomics (Hilic - installment 1)
FRAMINGHAM HEART STUDY CODING MANUAL Metabolomics (Hilic - installment 1) COHORT: Offspring TIME INTERVAL: Exam 5 DATASET NAME: l_mtbli1_ex05_1_0610s # OBSERVATIONS: 1075 High throughput metabolite profiling
BASIC METHODOLOGICAL STRATEGIES IN METABOLOMIC RESEARCH
SECTION 1 BASIC METHODOLOGICAL STRATEGIES IN METABOLOMIC RESEARCH 1 Exploring the Human Metabolome by Nuclear Magnetic Resonance Spectroscopy and Mass Spectrometry David S. Wishart Although most of the
Amino Acid Metabolism
Amino Acid Metabolism Last Week Most of the Animal Kingdom = Lazy - Most higher organisms in the animal kindom don t bother to make all of the amino acids. - Instead, we eat things that make the essential
Fate of Dietary Protein
Fate of Dietary Protein Dietary protein Stomach: l, pepsin Denatured and partially hydrolyzed protein (large polypeptides) small intestine: proteases Amino acids and dipeptides intestinal lining: proteases
0010 Amino Acids 40 Profile - Plasma
Accession #: Order #: G1234567 Date Collected: Date Received: 01/22/2013 Reference #: Patient: Date of Birth: 02/05/1962 Date of Report: Telephone: 7704464583 Ordering Physician: 1234 Main St. Anywhere,
Amino Acid Metabolism
Amino Acid Metabolism Fate of Dietary Protein Dietary protein Stomach: l, pepsin Denatured and partially hydrolyzed protein (large polypeptides) small intestine: proteases Amino acids and dipeptides intestinal
E.coli Core Model: Metabolic Core
1 E.coli Core Model: Metabolic Core 2 LEARNING OBJECTIVES Each student should be able to: Describe the glycolysis pathway in the core model. Describe the TCA cycle in the core model. Explain gluconeogenesis.
Xiaolei Xie, Marta Kozak. Thermo Fisher Scientific, 355 River Oaks Parkway, San Jose, CA Introduction
Comparison of Non-derivatization and Derivatization Tandem Mass Spectrometry Methods for Analysis of Amino Acids, Acylcarnitines, and Succinylacetone in Dried Blood Spots Xiaolei Xie, Marta Kozak Thermo
Metabolomics analyses to better understand complex phenotypes ZHONGHAO YU
Metabolomics analyses to better understand complex phenotypes ZHONGHAO YU München 2013 Aus dem HelmholtzZentrum München Deutsches Forschungszentrum für Gesundheit und Umwelt (GmbH) Institut für Epidemiologie
Supplementary material
Supplementary material Comprehensive Characterization and Evaluation for Hepatocellular Carcinoma by LC-MS based Serum Metabolomics Journal: Metabolomics Xin Lu 1,3, Huan Nie 1, Yiqun Li 1, Chao Zhan 2,
Short and Long Term Stability of 3-Hydroxy acylcarnitines Enriched Dried Blood Spots Stored at Various Temperatures and Humidities
Short and Long Term Stability of 3-Hydroxy acylcarnitines Enriched Dried Blood Spots Stored at Various Temperatures and Humidities Timothy Lim Biochemical Mass Spectrometry Laboratory Newborn Screening
Identification of Lipidomic Biomarkers for Coexposure to Subtoxic Doses of Benzo[a]pyrene and Cadmium: The Toxicological Cascade Biomarker Approach
![Identification of Lipidomic Biomarkers for Coexposure to Subtoxic Doses of Benzo[a]pyrene and Cadmium: The Toxicological Cascade Biomarker Approach](/thumbs/86/94000882.jpg "Identification of Lipidomic Biomarkers for Coexposure to Subtoxic Doses of Benzo[a]pyrene and Cadmium: The Toxicological Cascade Biomarker Approach")
Supporting Information Identification of Lipidomic Biomarkers for Coexposure to Subtoxic Doses of Benzo[a]pyrene and Cadmium: The Toxicological Cascade Biomarker Approach Harald Jungnickel,*,1 Sarah Potratz,
Amino acids. (Foundation Block) Dr. Essa Sabi
Amino acids (Foundation Block) Dr. Essa Sabi Learning outcomes What are the amino acids? General structure. Classification of amino acids. Optical properties. Amino acid configuration. Non-standard amino
Amino Acid Oxidation and the Urea Cycle
Amino Acid Oxidation and the Urea Cycle Amino Acids: Final class of biomolecules whose oxidation contributes significantly to the generation of energy Undergo oxidation in three metabolic circumstances
0010 Amino Acid Analysis - 40 Plasma
770.446.5483 770.441.2237 This report contains reference range adjustments from routine revalidation procedures. It also contains the following three upgrades: 1) The amino acids have been reorganized
Use of a Tandem Mass Spectrometry Research Method for the Analysis of Amino Acids and Acylcarnitines in Dried Blood Spots
Use of a Tandem Mass Spectrometry Research Method for the Analysis of Amino Acids and Acylcarnitines in Dried Blood Spots Xiaolei Xie and Marta Kozak Thermo Fisher Scientific, San Jose, CA, USA Application
Amino Acids. Amino Acids. Fundamentals. While their name implies that amino acids are compounds that contain an NH. 3 and CO NH 3
Fundamentals While their name implies that amino acids are compounds that contain an 2 group and a 2 group, these groups are actually present as 3 and 2 respectively. They are classified as α, β, γ, etc..
Lecture 10 - Protein Turnover and Amino Acid Catabolism
Lecture 10 - Protein Turnover and Amino Acid Catabolism Chem 454: Regulatory Mechanisms in Biochemistry University of Wisconsin-Eau Claire 1 Introduction 2 Proteins are degraded into amino acids. Protein
SUPPLEMENTARY DATA Supplementary Figure 1. Body weight and fat mass of AdicerKO mice.
SUPPLEMENTARY DATA Supplementary Figure 1. Body weight and fat mass of AdicerKO mice. Twelve week old mice were subjected to ad libitum (AL) or dietary restriction (DR) regimens for three months. (A) Body
Journal of Cell Science Supplementary information. Arl8b +/- Arl8b -/- Inset B. electron density. genotype
J. Cell Sci. : doi:.4/jcs.59: Supplementary information E9. A Arl8b /- Arl8b -/- Arl8b Arl8b non-specific band Gapdh Tbp E7.5 HE Inset B D Control al am hf C E Arl8b -/- al am hf E8.5 F low middle high
Lab Guide 2019 Metabolic Section Lab Guide
Lab Guide 2019 Metabolic Section Lab Guide Quantitative Amino acids Plasma Plasma. Container/Tube: Preferred EDTA, Place immediately in ice. Acceptable: lithium heparin, sodium heparin. Patient preparation:
Biochemistry: A Short Course
Tymoczko Berg Stryer Biochemistry: A Short Course Second Edition CHAPTER 30 Amino Acid Degradation and the Urea Cycle 2013 W. H. Freeman and Company Chapter 30 Outline Amino acids are obtained from the
Metabolomics approach reveals metabolic disorders and potential. biomarkers associated with the developmental toxicity of
Supplementary information for Metabolomics approach reveals metabolic disorders and potential biomarkers associated with the developmental toxicity of tetrabromobisphenol A and tetrachlorobisphenol A Guozhu
Lecture 11 - Biosynthesis of Amino Acids
Lecture 11 - Biosynthesis of Amino Acids Chem 454: Regulatory Mechanisms in Biochemistry University of Wisconsin-Eau Claire 1 Introduction Biosynthetic pathways for amino acids, nucleotides and lipids
Application of LC-MS-based metabolomics method in differentiating septic survivors from non-survivors
Analytical and Bioanalytical Chemistry Electronic Supplementary Material Application of LC-MS-based metabolomics method in differentiating septic survivors from non-survivors Zhicheng Liu, Peiyuan Yin,
AMINO ACID METABOLISM. Sri Widia A Jusman Dept. of Biochemistry & Molecular Biology FMUI
AMINO ACID METABOLISM Sri Widia A Jusman Dept. of Biochemistry & Molecular Biology FMUI Amino acids derived from dietary protein absorbed from intestine through blood taken up by tissues used for biosynthesis
Biochemistry: A Short Course
Tymoczko Berg Stryer Biochemistry: A Short Course Second Edition CHAPTER 30 Amino Acid Degradation and the Urea Cycle 2013 W. H. Freeman and Company In the cytosol of a cell amino groups from amino acids
Proteins consist in whole or large part of amino acids. Simple proteins consist only of amino acids.
Today we begin our discussion of the structure and properties of proteins. Proteins consist in whole or large part of amino acids. Simple proteins consist only of amino acids. Conjugated proteins contain
1. Describe the relationship of dietary protein and the health of major body systems.
Food Explorations Lab I: The Building Blocks STUDENT LAB INVESTIGATIONS Name: Lab Overview In this investigation, you will be constructing animal and plant proteins using beads to represent the amino acids.
Speaker: Paul De Smet. Thursday June 4th 2015
Speaker: Paul De Smet Thursday June 4th 2015 Your logo Stress Support: the nutritional answer to stress, infection and disease Thursday June 4th 2015 Table of content Stress Support: the nutritional answer
AMINO ACIDS STRUCTURE, CLASSIFICATION, PROPERTIES. PRIMARY STRUCTURE OF PROTEINS
AMINO ACIDS STRUCTURE, CLASSIFICATION, PROPERTIES. PRIMARY STRUCTURE OF PROTEINS Elena Rivneac PhD, Associate Professor Department of Biochemistry and Clinical Biochemistry State University of Medicine
9/6/2011. Amino Acids. C α. Nonpolar, aliphatic R groups
Amino Acids Side chains (R groups) vary in: size shape charge hydrogen-bonding capacity hydrophobic character chemical reactivity C α Nonpolar, aliphatic R groups Glycine (Gly, G) Alanine (Ala, A) Valine
Full Report (All Nutrients) 01174, Milk, reduced fat, fluid, 2% milkfat, without added vitamin A and vitamin D
National base for Standard Reference Release 28 slightly revised May, 206 Full Report (All s) 074, Milk, reduced fat, fluid, 2% milkfat, without added vitamin A and vitamin D Report Date: February 23,
Nitrogen Metabolism. Overview
Nitrogen Metabolism Pratt and Cornely Chapter 18 Overview Nitrogen assimilation Amino acid biosynthesis Nonessential aa Essential aa Nucleotide biosynthesis Amino Acid Catabolism Urea Cycle Juicy Steak
M1 - Renal, Fall 2007
University of Michigan Deep Blue deepblue.lib.umich.edu 2007-09 M1 - Renal, Fall 2007 Lyons, R.; Burney, R. Lyons, R., Burney, R. (2008, August 07). Renal. Retrieved from Open.Michigan - Educational Resources
Tomoko Tanahashi 1, Yasushi Tsuchihashi 3*, Akiyo K. Sakamiya 1 1, 2. and Takeo Yano
Metabolomic approach using ultra-high-performance liquid chromatography-mass spectrometry: Quantitative amino acid analysis and characterization of four species of marine fish, and a cuttlefish Tomoko
Supplementary Information. Effects of Perfluorooctanoic Acid on Metabolic Profiles in Brain and Liver of Mouse by a
Supplementary Information Effects of Perfluorooctanoic Acid on Metabolic Profiles in Brain and Liver of Mouse by a High-throughput Targeted Metabolomics Approach Nanyang Yu, Si Wei, *, Meiying Li, Jingping
Dental Students Biochemistry Exam V Questions ( Note: In all cases, the only correct answer is the best answer)
Dental Students Biochemistry Exam V Questions - 2006 ( Note: In all cases, the only correct answer is the best answer) 1. Essential fatty acids are: A. precursors of biotin B. precursors of tyrosine C.
Short polymer. Dehydration removes a water molecule, forming a new bond. Longer polymer (a) Dehydration reaction in the synthesis of a polymer
HO 1 2 3 H HO H Short polymer Dehydration removes a water molecule, forming a new bond Unlinked monomer H 2 O HO 1 2 3 4 H Longer polymer (a) Dehydration reaction in the synthesis of a polymer HO 1 2 3
Lecture 3: 8/24. CHAPTER 3 Amino Acids
Lecture 3: 8/24 CHAPTER 3 Amino Acids 1 Chapter 3 Outline 2 Amino Acid Are Biomolecules and their Atoms Can Be Visualized by Two Different Ways 1) Fischer projections: Two dimensional representation of
Amino acids. You are required to know and identify the 20 amino acids : their names, 3 letter abbreviations and their structures.
Amino acids You are required to know and identify the 20 amino acids : their names, 3 letter abbreviations and their structures. If you wanna make any classification in the world, you have to find what
Lecture 17: Nitrogen metabolism 1. Urea cycle detoxification of NH 3 2. Amino acid degradation
Lecture 17: Nitrogen metabolism 1. Urea cycle detoxification of NH 3 2. Amino acid degradation Reference material Biochemistry 4 th edition, Mathews, Van Holde, Appling, Anthony Cahill. Pearson ISBN:978
Biomolecules. Presented by Amelia McCutcheon
Biomolecules Presented by Amelia McCutcheon Fats Carbohydrates Proteins Vitamins Fats Also known as lipids Fats are solids (high mel=ng point) ils are liquids (low mel=ng point) Mainly consist of Carbon
AMINO ACIDS NON-ESSENTIAL ESSENTIAL
Edith Frederika Introduction A major component of food is PROTEIN The protein ingested as part of our diet are not the same protein required by the body Only 40 to 50 gr of protein is required by a normal
Stable Isotope-Labeled Products
isotope.com RESEARCH PRDUCTS Stable Isotope-Labeled Products For Metabolomics Cambridge Isotope Laboratories, Inc. North America: 1.800.322.1174 cilsales@isotope.com International: +1.978.749.8000 intlsales@isotope.com
Metabolism of amino acids I. Josef Fontana
Metabolism of amino acids I Josef Fontana EC Overview of the lecture Introduction to protein and amino acids metabolism Metabolic pathways of amino acids Transamination Conversion glutamate - glutamine
Cleveland Clinic Laboratories
Cleveland Clinic Laboratories Technical Update December 2018 Cleveland Clinic Laboratories is dedicated to keeping you updated and informed about recent testing changes. This Technical Update is provided
number Done by Corrected by Doctor Dr.Diala
number 32 Done by Mousa Salah Corrected by Bahaa Najjar Doctor Dr.Diala 1 P a g e In the last lecture we talked about the common processes between all amino acids which are: transamination, deamination,
Fatty acids and phospholipids
PYS 4xx Intro 2 1 PYS 4xx Intro 2 - Molecular building blocks We now describe in more detail the nomenclature and composition of several classes of compounds of relevance to the cell, including: membrane
Four Classes of Biological Macromolecules. Biological Macromolecules. Lipids
Biological Macromolecules Much larger than other par4cles found in cells Made up of smaller subunits Found in all cells Great diversity of func4ons Four Classes of Biological Macromolecules Lipids Polysaccharides
LAB#23: Biochemical Evidence of Evolution Name: Period Date :
LAB#23: Biochemical Evidence of Name: Period Date : Laboratory Experience #23 Bridge Worth 80 Lab Minutes If two organisms have similar portions of DNA (genes), these organisms will probably make similar
AbsoluteIDQ Kit: Targeted Metabolomics Identification and Quantification
AbsoluteIDQ Kit: Targeted Metabolomics Identification and Quantification Accurate, Reproducible, Metabolomics Studies The word metabolome refers to the complete set of small molecule metabolites arising
Hydroxycarboxylic acid receptors are essential for breast cancer cells to control their lipid/fatty acid metabolism
Hydroxycarboxylic acid receptors are essential for breast cancer cells to control their lipid/fatty acid metabolism Supplementary Material Supplemental Tables Table S1: Origin and pathology verification
Page 8/6: The cell. Where to start: Proteins (control a cell) (start/end products)
Page 8/6: The cell Where to start: Proteins (control a cell) (start/end products) Page 11/10: Structural hierarchy Proteins Phenotype of organism 3 Dimensional structure Function by interaction THE PROTEIN
Food for special medical purposes. phenylketonuria (PKU) Important notice: Suitable only for individuals with proven phenylketonuria.
PKU Nutri 1 Energy Food for special medical purposes. For the dietary management of proven phenylketonuria (PKU) in infants from birth to 12 months and as a supplementary feed up to 3 years. An amino acid
Large-Scale Metabolite Analysis by Laser Desorption Ionization Mass Spectrometry from Silicon Nanopost Arrays
Supporting Information Large-Scale Metabolite Analysis by Laser Desorption Ionization Mass Spectrometry from Silicon Nanopost Arrays Andrew R. Korte, Sylwia A. Stopka, Nicholas Morris, Trust Razunguzwa,
Fundamentals of Organic Chemistry CHEM 109 For Students of Health Colleges
Fundamentals of Organic Chemistry CHEM 109 For Students of Health Colleges Credit hrs.: (2+1) King Saud University College of Science, Chemistry Department CHEM 109 CHAPTER 9. AMINO ACIDS, PEPTIDES AND
Biology. Lectures winter term st year of Pharmacy study
Biology Lectures winter term 2008 1 st year of Pharmacy study 3 rd Lecture Chemical composition of living matter chemical basis of life. Atoms, molecules, organic compounds carbohydrates, lipids, proteins,
Stable Isotope-Labeled Products For Metabolomics
Cambridge Isotope Laboratories, Inc. RESEARCH PRDUCTS Stable Isotope-Labeled Products For Metabolomics Cambridge Isotope Laboratories, Inc. http://www2.otsuka.co.jp/cil/ isotope@otsuka.jp Cambridge Isotope
BODY CHEMISTRY TEST. Sample Report
BODY CHEMISTRY TEST * Sample Report Ver. 1.0, Date created: Nov 5, 2017 Disclaimer: VitaminLab is for informational purposes only. lease discuss your results or concerns with your health care professional
Amino acids-incorporated nanoflowers with an
Amino acids-incorporated nanoflowers with an intrinsic peroxidase-like activity Zhuo-Fu Wu 1,2,+, Zhi Wang 1,+, Ye Zhang 3, Ya-Li Ma 3, Cheng-Yan He 4, Heng Li 1, Lei Chen 1, Qi-Sheng Huo 3, Lei Wang 1,*
Glycolysis. Cellular Respiration
Glucose is the preferred carbohydrate of cells. In solution, it can change from a linear chain to a ring. Energy is stored in the bonds of the carbohydrates. Breaking these bonds releases that energy.
Quantitative analysis of hydrophilic metabolite using ion-paring chromatography with a high-speed triple quadrupole mass spectrometer
Quantitative analysis of hydrophilic metabolite using ion-paring chromatography with a high-speed triple ASMS 2012 ThP11-251 Zanariah Hashim 1 ; Yudai Dempo1; Tairo Ogura 2 ; Ichiro Hirano 2 ; Junko Iida
Supporting Information
Supporting Information Chaleckis et al. 10.1073/pnas.1603023113 SI Materials and Methods Human Subject Characteristics. Thirty healthy male and female volunteers participated in this study (Table S2).
Metabolomic Data Analysis with MetaboAnalystR
Metabolomic Data Analysis with MetaboAnalystR Name: guest623839008349489450 February 7, 2018 1 Background Understanding the functional importance of metabolites in untargeted metabolomics is limited due
Nitrogen Metabolism. Pratt and Cornely Chapter 18
Nitrogen Metabolism Pratt and Cornely Chapter 18 Overview Nitrogen assimilation Amino acid biosynthesis Nonessential aa Essential aa Nucleotide biosynthesis Amino Acid Catabolism Urea Cycle Juicy Steak
Reactions and amino acids structure & properties
Lecture 2: Reactions and amino acids structure & properties Dr. Sameh Sarray Hlaoui Common Functional Groups Common Biochemical Reactions AH + B A + BH Oxidation-Reduction A-H + B-OH + energy ª A-B + H
GL Science Inertsearch for LC Inertsil Applications - Acids. Data No. Column Data Title Solutes Eluent Detection Data No.
GL Science Inertsearch for LC Inertsil Applications: Acids For complete Product Description, Chromatograms Price & Delivery in Australia & New Zealand contact info@winlab.com.au or call 61 (0)7 3205 1209
(a) (i) Describe how the production and action of interferon differs from the production and action of lysozyme. (3)
1 Histamine and the proteins interferon and lysozyme are involved in the non-specific responses to infection. (a) (i) escribe how the production and action of interferon differs from the production and
18 Amino Acid Oxidation and Production of Urea W. H. Freeman and Company
18 Amino Acid Oxidation and Production of Urea 2013 W. H. Freeman and Company 1 Last Class of Biomolecules For Energy 1. Production of acetyl-coa. Glucose. To pyruvate via glycolysis. To acetyl-coa by
New biomarkers for assessing kidney diseases
Lundin 2009 New biomarkers for assessing kidney diseases Publication number WO2010139341 A1 Publication type Application Application number PCT/EP2009/003926 Publication date Dec 9, 2010 Filing date Jun
Objective: You will be able to explain how the subcomponents of
Objective: You will be able to explain how the subcomponents of nucleic acids determine the properties of that polymer. Do Now: Read the first two paragraphs from enduring understanding 4.A Essential knowledge:
AMINO ACID METABOLISM
AMINO ACID METABOLISM PHL-285 Biochemistry-2 Mahmoud N. Nagi, Ph.D. Professor of Biochemistry Overview of amino acid metabolism. Classification of amino acids. Biosynthesis of nonessential amino acids.
Supporting Information. New Insights into the Cytotoxic Mechanism of. Hexabromocyclododecane from a Metabolomic Approach
Supporting Information New Insights into the Cytotoxic Mechanism of Hexabromocyclododecane from a Metabolomic Approach Feidi Wang,, Haijun Zhang, *, Ningbo Geng,, Baoqin Zhang, Xiaoqian Ren,, Jiping Chen
PROTEIN. By: Shamsul Azahari Zainal Badari Department of Resource Management and Consumer Studies Faculty of Human Ecology UPM
PROTEIN By: Shamsul Azahari Zainal Badari Department of Resource Management and Consumer Studies Faculty of Human Ecology UPM OBJECTIVES OF THE LECTURE By the end of this lecture, student can: Define
Table S1. Identified metabolites in rats plasma
Electronic Supplementary Material (ESI) for Molecular BioSystems. This journal is The Royal Society of Chemistry 2015 Table S1. Identified metabolites in rats plasma NO Retention time Metabolites Level
Biomolecules: amino acids
Biomolecules: amino acids Amino acids Amino acids are the building blocks of proteins They are also part of hormones, neurotransmitters and metabolic intermediates There are 20 different amino acids in
Preface to the Second Edition... xv Preface to the First Edition... xvii Author... xix. Introduction
Contents Preface to the Second Edition... xv Preface to the First Edition... xvii Author... xix Part I The Theory Chapter 1 Proteins and Amino Acids... 3 Introduction... 3 Amino Acids... 4 Peptide Linkage...
Carbohydrates. Building a carbohydrate:
Carbohydrates Monomer: Monosaccharide (simple s) Example: glucose, fructose Disaccharide: 2 monosaccharides joined together Example: sucrose (glucose + fructose) olymer: olysaccharide (starch) Example:
Chapter 5: Structure and Function of Macromolecules AP Biology 2011
Chapter 5: Structure and Function of Macromolecules AP Biology 2011 1 Macromolecules Fig. 5.1 Carbohydrates Lipids Proteins Nucleic Acids Polymer - large molecule consisting of many similar building blocks
MSUD HCU Tyrosinaemia MMA/PA IVA (for PKU cooler see pages 11-13)
(for PKU see pages 11-13) + Description A food for special medical purposes. Cooler is a ready-to-drink protein substitute containing essential and non-essential amino acids (but excluding the offending
Metabolism of amino acids. Vladimíra Kvasnicová
Metabolism of amino acids Vladimíra Kvasnicová Classification of proteinogenic AAs -metabolic point of view 1) biosynthesis in a human body nonessential (are synthesized) essential (must be present in
Nitrogen Metabolism. Overview
Nitrogen Metabolism Pratt and Cornely Chapter 18 Overview Nitrogen assimilation Amino acid biosynthesis Nonessential aa Essential aa Nucleotide biosynthesis Amino Acid Catabolism Urea Cycle Juicy Steak
Annual Report ERNDIM-EQAS Quantitative Amino Acids 2002
Annual Report ERNDIM-EQAS Quantitative Amino Acids 2002 1. Purpose The purpose of the ERNDIM External Quality Assurance Scheme for Quantitative Organic Acids is the monitoring of the analytical quality
Amino acid metabolism II
Amino acid metabolism II Fates of amino acid carbon skeleton degradation to common intermediates pyruvate, intermediates of citric acid cycle, acetyl-coa Glucogenic AA precursors of glucose - degradation
SUMMARY OF PRODUCT CHARACTERISTICS
SUMMARY OF PRODUCT CHARACTERISTICS 1. NAME OF THE MEDICINAL PRODUCT PRIMENE 10% 2. QUALITATIVE AND QUANTITATIVE COMPOSITION Each litre of the infusion solution contains: L-Isoleucine L-Leucine L-Valine
S-01 SUPPORTING INFORMATION. TITLE: Inter-laboratory reproducibility of a targeted metabolomics platform for analysis of human serum and plasma
SUPPORTING INFORMATION TITLE: Inter-laboratory reproducibility of a targeted metabolomics platform for analysis of human serum and plasma Alexandros P. Siskos, 1 Pooja Jain, 1 Werner Römisch-Margl, 2 Mark
Differences in elongation of very long chain fatty acids and fatty acid metabolism between triple-negative and hormone receptor-positive breast cancer
Yamashita et al. BMC Cancer (2017) 17:589 DOI 10.1186/s12885-017-3554-4 RESEARCH ARTICLE Open Access Differences in elongation of very long chain fatty acids and fatty acid metabolism between triple-negative
PHAR3316 Pharmacy biochemistry Exam #2 Fall 2010 KEY
1. How many protons is(are) lost when the amino acid Asparagine is titrated from its fully protonated state to a fully deprotonated state? A. 0 B. 1 * C. 2 D. 3 E. none Correct Answer: C (this question
So where were we? But what does the order mean? OK, so what's a protein? 4/1/11
So where were we? We know that DNA is responsible for heredity Chromosomes are long pieces of DNA DNA turned out to be the transforming principle We know that DNA is shaped like a long double helix, with