LIST OF AVAILABLE ASSAYS. Methods/Platforms. Biomarkers Core Laboratory 622 West 168th Street PH New York, NY

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1 Biomarkers Core Laboratory 622 West 168th Street PH New York, NY Tel LIST OF AVAILABLE ASSAYS Assay Methods/Platforms 25 hydroxy Vitamin D2, D3 3-Aminopropanol Acetoacetate ACY-1215 Acylcarnitines * Adiponectin Adrenocorticotropic Hormone AGE-CML Alisertib Alpha 1-Antichymotrypsin (AACT) Alpha 2-macroglobulin Alpha-Synuclein Alsterpaullone Aminoacids * Androstenedione Angiopoietin-1 (ANG1) Angiopoietin-2 (ANG2) Anti-Mullerian Hormone (AMH) Anti-Rheumatoid Factor IgM (RF IgM) Apolipoprotein A1 (Apo AI) Apolipoprotein AII (Apo AII) Apolipoprotein B (Apo B), Apolipoprotein B48 (Apo B48) Apolipoprotein CII (Apo CII),, Apolipoprotein CIII (Apo CIII),, Apolipoprotein E (Apo E) Apolipoprotein Turnover Kinetics APP bctf AR-12 BDNF Beta Amyloid I-40 Beta Amyloid I-42 Beta-Hydroxybutyrate Bile Acids * Biocrates P180 Kit Metabolomics Panel* Biogenic amines * Biospecimen processing (Blood, Saliva, Urine) Bone TRAcP

2 BoneALP Brain Natriuretic Peptide (BNP) BUN Calcium Carotenoids * Caspase-1/ICE Cathelicidin (LL-37) CCL11/Eotaxin CCL18/PARC CD14, soluble CD146 CD163, soluble CD30 Ceramides * Cholesterol Collagen Crosslinks Panel * Complement Component C4a Complement Component C4b Cortisol Cortisol Cotinine C-peptide Creatinine CRH CRPhs C-terminal Telopeptide (CTx) CXCL10 / IP10 Cyclic Citrullinated Peptide (CCP3 IgG) Cystatin C Cytokines/Chemokines Multiplex Panel D-Dimer DHEA DHEA-S DHT, Testosterone DNA Methylation Dofetilide Dopamine Endocannabinoids * Endoglin Endothelin-1 Epinephrine Erlotinib E-Selectin Estradiol Estradiol, Progesterone, and Testosterone Estrone Estrone Sulfate Estrone, Estradiol, Testosterone, LUMINEX

3 Ethinyl Estradiol Etonogestrel Etoposide Fentanyl FGF-23 C-Term FGF-Basic Fibrinogen Fibroblast Growth Factor 21 (FGF21) Free Fatty Acids * Fructosamine FSH Galectin-1 Galectin-3 Ghrelin GIP (Total) Glucagon Glucagon Like Peptide-1 (GLP-1) Glucose Glycerol Growth Hormone (GRH) GUCA2A HbA1c hcg HDL-C Hepatocyte growth factor (HGF) Hepcidin High Mobility Group Box 1 (HMGB1) Homocysteine Ibrutinib ICAM-1, CD54 ICTP I-FABP IFN-gamma IGF-1 IGFBP-3 IL-10 IL-10 Hs IL-1b IL-2 IL-4 Hs IL-6 IL-7 IL-8 Insulin Irisin Isoprostane Ketamine KU60019 Colorimetric,,,

4 Kynurenine Lactate LDL-C direct Leptin Levonorgestrel Lipopolysaccharide Binding Protein (LBP) Lipopolysacharide (LPS) LONZA LL-37 / Cathelicidin LOC14 LPa Luteinzing Hormone (LH) Matrilysin (MMP7-Total) Medroxy Progesterone Acetate (MPA) Melatonin MEW3144 Midozolam Drug Panel Minocycline MIP2/CXCL2 MMAE, Bendamustine MMI-270 Neopterin Nerve Growth Factor (NGF) Neuron Specific Enolase (NSE) NGAL, N-telopeptide (NTx) O-75 Organic Acids * GCMS Osteocalcin Osteoprotegerin (OPG) Oxytocin Paclitaxel Pancreatic Polypeptide (PP) Parathyroid hormone (PTH) PCSK9, Pentosidine, Peptide YY (PYY) Placenta Growth Factor (PLGF) Plasminogen Activator Inhibitor (PAI -1) Polyamines* Pralatrexate Procollagen I intact N-terminal (P1NP) Progesterone Prolactin P-Selectin, soluble PTH-Intact PTH-Whole RAGE RANKL (Total)

5 Retinal, Retinol & Retinyl Ester Retinoic Acid Metabolites * Romidepsin Ropinirole S100 Calcium Binding Protein Sclerostin Serotonin SHBG Sirolimus/Temsirolimus Sphingomyelin Sphingosine/Spinganine Surfactant Protein D (SP-D) T3 free T3 total T4 free T4 total TAC Tamoxifen TARC/CCL17 TBARS Testosterone TGF-β TNF RI, Soluble TNF RII, Soluble TNF-α Transcortin Transferrin Triglycerides Trimethyamine N-Oxide (TMAO) Troponin 1 Tryptophan TSH Tumor necrosis factor α (TNF-α) Ulipristal acetate Uric acid µpar Vasopressin VCAM, soluble VEGF VEGF R1/ Flt1 Vitamin B12 Vitamin B6 Vitamin D Binding protein (VDBP) Vitamin D Metabolites* Zonulin (Haptoglobin) Colorimetric * Targeted Metabolomic Panels: Please contact Renu Nandakumar, PhD (rn2374@cumc.columbia.edu) for more information on the analytes included in each panel.

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