Reference Intervals. Graham Jones / Gus Koerbin
|
|
- James Gordon
- 5 years ago
- Views:
Transcription
1 Reference Intervals Graham Jones / Gus Koerbin
2 Adult CRI - Harmonisation Harmonisation : (13 tests + 1 calculation) Harmonisation : Confirm 2012 recommendations. Discussed: albumin, globulin, AST & ALT (+/- P5P), GGT, bilirubin, Lipase (KC, GC). Aussie normal, Bias 2 study (GK) Harmonisation : summary of data used for decision making and between lab analytical differences (AoN, local and international). Flagging rates for common analytes on different systems raw data included (KS). IMPLEMENT! Next analytes: Albumin, globulin, bilirubin, GGT, lipase Harmonisation : ALT x 40 (M); X-35 (F) X=5? (Non-P5P) AST x -35 (M), x 30 (F) (Non P5P) X=5? Albumin: recommend age-related. Bilirubin: x-20 (labs to decide X) Data for CK, GGT, Lipase, Urea Harmonisation : Uptake of CRI (1 st set of analytes), baseline for 2 nd set of analytes) Next analytes: albumin, urea, TF, blood gases, FBC, Common intervals (GC) Harmonisation : Urea intervals recommended Discussion on: blood gases, iron studies
3 Adult CRI - Publications Tate et al. for AACB WP on CRI. Harmonising adult and paediatric common reference intervals in Australia and New Zealand for a first panel of chemistry analytes. Clin Biochem Rev 2014;35: Vasikaran et al. Harmonised Australian Reference Intervals for Serum PINP and CTX in Adults. Clin Biochem Rev 2014;34(4): Graham Jones and Sabrina Koetsier. RCPAQAP First Combined Measurement and reference interval survey. Clin Biochem Revs 2014: Jones GRD, Koetsier S. Uptake of recommended common reference intervals for chemical pathology in Australia. Ann Clin Biochem 2017;54: G Jones, K Sikaris, Jan Gill. Allowable Limits of Performance for External Quality Assurance Programs an Approach to Application of the Stockholm Criteria by the RCPA Quality Assurance Programs. Clin Biochem revs. 2012;33: Koerbin G et al. for AACB WP on CRI. Harmonising Adult Reference Intervals Mini-Review Harmonising Adult Reference Intervals in Australia and New Zealand the Continuing Story. Clin Biochem rev 2016;37:131-4 [CK, ALT, AST, GGT, Lipase] Maxine Reed. The New Zealand Approach to harmonised reference intervals. Clin Biochem Revs, 2012;33: Gus Koerbin et al for AACB WP on CRI. Bias Assessment of General Chemistry Analytes using Commutable Samples. Clin Biochem Revs 2014;35: Graham Jones, Reiner Haeckel, Alex Katayev, Y. Ozarda, Tze Ping Loh, Ken Sikaris IFCC C- RIDL: Indirect methods for reference interval determination - Review and recommendations. CCLM 2018
4 Paediatric CRI Harmonisation : proposed paediatric reference intervals (7 tests) Harmonisation : Confirmed 2012 recommendations. Harmonisation : common analytes data mining data available on line!! Age partitioning definitions (RF) Harmonisation : TFT (Caliper + manufacturers), Ammonia Harmonisation : Update (Tina Yen) sweat testing, ammonia, benchmarking, dynamic testing, AMH, neonatal bilirubin, egfr (Schwartz), new analytes
5 Pregnancy CRI Harmonisation : proposed pregnancy reference intervals (16 tests + 2 calculations) Harmonisation : Detailed data (Na, K, Cl, urea, creatinine, osmolality, AG, bicarbonate) (N Hadlow). Conclusions: Na ; Cl ; K (serum); urea ; creat Timing of gestation (Peter Ward) recommendations Rasied: urate, AG, bicarbonate, albumin, FBC, urine protein, urine albumin Harmonisation : Proposed intervals and flagging rates. Raw data available (KS) Harmonisation : TFT (Zhong Lu, Ken Sikaris) Harmonisation : (Zhong Lu, Ken Sikaris) Thyroid function testing in pregnancy (Dr Simon Forehan) Pregnancy RI review (Ken Sikaris); LIS issues (Tina yen) Publications Narelle Hadlow and Ken Sikaris. Aspects to consider in adopting pregnancy specific reference intervals. Clin Biochem Revs 2015;36: Alan McNeil and Phoebe Stanford. Reporting thyroid function tests in pregnancy. Clin Biochem Revs. 2015;36:109-26
6 Reference Interval harmonisation DATA FOR KEY COMPONENTS Methods give close enough results EQA data, GKs sample swap, average of normal data Reference interval to share Data from manufacturers; Aussie normals, current lab usage (EQA); literature; data mining (Sonic + others) Effect of intervals Flagging Rates
7 1 st Common Reference Intervals Clinical Biochemist Reviews 2014;35:
8 Analyte Male Female Calcium Phosphate Magnesium LDH [L to mmol/l mmol/l mmol/l U/L P]IFCC Sodium Potassium Chloride Bicarbonate mmol/l mmol/l mmol/l mmol/l Creatinine umol/l umol/l ALP U/L AST <40 <35 ALT <40 <30 Total Protein g/l
9
10 Jones GRD, Koetsier S Ann Clin Biochem 2016
11
12
13 Jones GRD, Koetsier S Ann Clin Biochem 2016
14 2017
15
16 Common Reference Intervals Actual
17 Why Not? Unaware Not important enough / too busy No problems here mate! Insufficient evidence Specific scientific objection Unable to get local agreement Keep local customers happy Were we wrong before? Multiple factors
18 Manufacturers - Instruments
19 Sodium 83% 90%
20 Sodium (average of normal)
21 Potassium (yellow = OCD) 92% 57%
22 Magnesium 90% 72%
23 Bicarbonate 75% 90%
24 Bicarbonate LSC 2017 DIFFERENCE FROM MEDIAN (mmol/l) Abbott Siemens Advia Siemens Dade Roche Hitachi Ortho Beckman AU DIFFERENCE / Reference interval Width Abbott Siemens Advia Siemens Dade Roche Hitachi Ortho Beckman AU
25 Phosphate (yellow = OCD) 56% 90%
26 ALP (Beckman AU in Yellow) ~70% ~45%
27
28 CK (OCD in yellow) CRI: U/L (M <60 years) 30%
29 ALT (no P5P in yellow) CRI: 5 35 U/L (female) <5%
30 GGT CRI: 5 50 U/L (male) 28% 45%
31 Lipase CRI: U/L 15% 40%
32 Common Reference Intervals nd round
33 Urea M40 F40
34 Albumin (BCP in yellow)
35 Iron
36
37 Calculations WP 2017 Meeting
38 Anion Gap (with K) (75/89) AG: Siemens Advia (median = 13) AG: Roche Hitachi (median = 21)
39 Anion Gap Liquid Serum Chemistry - sample Siemens Advia Siemens Dade Abbott Beckman AU OCD Roche Hitachi Median Mean S.D %CV 19% 12% 10% 14% 10% 10% Pred CV 6% 4% 6% 5% 3% 6%
40 Calculations WP 2017 Meeting
41 Calculations WP 2017 Meeting
42
43 Calcium
44 Bicarbonate
45 Chloride
46 egfr
47
48
49 Cholesterol
50 HDL Cholesterol
51
52 Adult Reference Intervals Urea Recommendations Common reference intervals for Urea (all) (methods suitable) Age and sex related intervals (17:3; Aust v NZ) Intervals:
53 Adult Reference Intervals Iron Studies Iron Can share intervals (assays suitable based) Limited data on methods Data mining less useful Reference interval studies difficult NSW Health Pathology Have compared methods Have surveyed intervals Prepared to share information (thank you)
54 S1 S2 Albumin g/l Amylase U/L Cholesterol mmol/l Creatinine umol/l Glucose mmol/l Lactate U/L LDH U/L Lipase U/L Osmolality mmol/kg ph Protein g/l Sodium mmol/l Triglycerides mmol/l
55 Albumin Body Fluids Pilot
56 Amylase Body Fluids Pilot
57 Glucose Body Fluids Pilot
58 Lactate Body Fluids Pilot
59 Total protein Body Fluids Pilot
60 Triglycerides Body Fluids Pilot
61 CEA Body Fluids Pilot
62 Triglycerides Mid -2SD +2SD Target Max between method bias 0.2 mmol/l
63 Total Cholesterol Mid -2SD +2SD Target Max between method bias 0.7 mmol/l ( )
64 HDL Cholesterol Mid -2SD +2SD Target Max between method bias 0.25 mmol/l ( )
65 Non-HDL Cholesterol Mean Average -2SD +2SD
66 LDL Cholesterol
Evidence Based Commutability: Bias 2 Study. Janice Gill Manager RCPAQAP Chemical Pathology Adelaide SA
Evidence Based Commutability: Bias 2 Study Janice Gill Manager RCPAQAP Chemical Pathology Adelaide SA Australian Bias Studies conducted by Gus Koerbin, ACT Pathology on behalf of AACB Harmonisation Committee
More informationHarmonisation of Reference Ranges
Harmonisation of Reference Ranges Ken Sikaris BSc(Hons), MBBS, FRCPA, FAACB, FFSc Vice President, AACB (Education) Chemical Pathologist, Melbourne Pathology Director of Clinical Support Systems, Sonic
More informationThe Whats and Hows of Reference Intervals. Graham Jones Department of Chemical Pathology St Vincent s Hospital, Sydney
The Whats and Hows of Reference Intervals Graham Jones Department of Chemical Pathology St Vincent s Hospital, Sydney Surabaya Indonesia 2016 Acknowledgements Reference Intervals - Summary What are they
More informationImpact of Proposed HRI s on Laboratory Report Flagging Rates
Impact of Proposed HRI s on Laboratory Report Flagging Rates A/Prof. Ken Sikaris Melbourne Pathology BSc(Hons), MBBS, FRCPA, FAACB, FFSc CBN 2011 WORKSHOP 2012 WORKSHOP 2013 WORKSHOP 2014 GENERAL CONCEPTS
More informationSetting of quality standards
Setting of quality standards Graham Jones Department of Chemical Pathology St Vincent s Hospital, Sydney AACB ASM Adelaide October 2014 Setting of Quality Standards - 2013 The 2013 QC workshop revealed
More informationQuality Initiative In Pathology. Harmonisation of Laboratory Testing
Quality Initiative In Pathology Harmonisation of Laboratory Testing Harmonisation: what do we mean? Agreement of test results irrespective of the method used or the testing laboratory Requires: Common
More informationConfirmation - A Practical Approach
Data Mining i for Reference Interval Confirmation - A Practical Approach Graham Jones Chemical Pathologist St Vincent s Hospital, Sydney AACB Webinar 5 th June 2013 Summary A little (more) background Current
More informationBreakout Session C: Harmonisation of the Alert Table.
Breakout Session C: Harmonisation of the Alert Table. RCPA-AACB High Risk Results Working Party Andrew Georgiou Craig Campbell Grahame Caldwell Hans Schneider Penelope Coates Que Lam Rita Horvath Robert
More informationNarelle Hadlow, Peter Ward, Ken Sikaris
Narelle Hadlow, Peter Ward, Ken Sikaris Analytes for consideration Vascular, renal and Na and water changes Consider physiology and review data Na, K, Cl, Urea, Cr, Osm Acid base status Consider physiology
More informationBody Fluids EQA. Rizzi de Leon. Royal College of Pathologists Australasia Quality Assurance Programs (RCPAQAP) Pathology Update Melbourne, Australia
Body Fluids EQA Royal College of Pathologists Australasia Quality Assurance Programs (RCPAQAP) Pathology Update Melbourne, Australia 22-24 February 2019 What is a Body Fluid? https://en.wikipedia.org/wiki/ascites
More informationROTUNDA HOSPITAL DEPARTMENT OF LABORATORY MEDICINE
This active test table informs the user of Biochemistry tests available in house. s referred to other sites are recorded in the Referred Table. Issue date: 4 TH April 2016 Contact Phone Number ext.1345/2522
More informationGeneral Chemistry Scheme Guide
General Chemistry Scheme Guide Copyright WEQAS. All rights reserved. No part of this document may be reproduced or utilised in any form without permission from WEQAS Contents. Scheme details and repertoire.....
More informationAUSTRALIAN PATHOLOGY UNITS AND TERMINOLOGY (APUTS) Harmonised Reference Intervals Chemical Pathology. (v1.1)
AUSTRALIAN PATHOLOGY UNITS AND TERMINOLOGY (APUTS) Harmonised Reference Intervals Chemical Pathology (v1.1) ISBN: Pending 1 State Health Publication Number (SHPN): Pending Online copyright RCPA 2014 This
More informationChemistry Reference Ranges and Critical Values
Alanine Aminotransferase (ALT, SGPT) 3-9 years 9-18 years 1-9 years 9-18 years 10-25 U/L 10-35 U/L 10-30 U/L 10-25 U/L 10-30 U/L 10-35 U/L 10-25 U/L 10-35 U/L 10-25 U/L 10-20 U/L 10-35 U/L Albumin 0-6
More informationChemistry Reference Ranges and Critical Values
Alanine Aminotransferase (ALT, SGPT) 3-9 years 9-18 years 1-9 years 9-18 years 10-30 U/L 10-30 U/L 10-20 U/L Albumin 0-6 days 6 days - 37 months 37 months - 7 years 7-20 years 2.6-3.6 g/dl 3.4-4.2 g/dl
More informationAuthorised: JSWoodford, Lead of Speciality. Biochemistry Reference Intervals, October Page 1 of 5
AFP All All < 15 ug/l Albumin All 0-3M 25-40 g/l Albumin All 3-12M 32-45 g/l Albumin All 1-70Y 34-48 g/l Albumin All >70Y 32-46 g/l Alk Phos All 0-10Y 80-350 U/L Alk Phos M 10-14Y 45-400 U/L Alk Phos F
More informationSchedule of Accreditation issued by United Kingdom Accreditation Service 2 Pine Trees, Chertsey Lane, Staines-upon-Thames, TW18 3HR, UK
2 Pine Trees, Chertsey Lane, Staines-upon-Thames, TW18 3HR, UK Biochemistry Department University Hospital of North Durham Durham County Durham DH1 5TW Contact: Dr Tim Lang Tel: +44 (0) 191 333 2694 Fax:
More informationWhat tests should be on the Alert List?
What tests should be on the Alert List? Dr Que Lam On behalf RCPA-AACB High Risk Results Working Party: Alan McNeil, Grahame Caldwell, Craig Campbell, Penelope Coates, Robert Flatman, Andrew Georgiou,
More informationEvaluation of VACUETTE CAT Serum Fast Separator Blood Collection Tube for Routine Chemistry Analytes in Comparison to VACUTAINER RST Tube
Evaluation of VACUETTE CAT Serum Fast Separator Blood Collection Tube for Routine Chemistry Analytes in Comparison to VACUTAINER RST Tube Background: Greiner-Bio-One, Austria has been selling plastic evacuated
More informationNEW RCPCH REFERENCE RANGES-
s vary between populations and age groups and it is important to always check the reference Haematology: Haemoglobin Male 130 175 g/l 0 6 days 145-220 g/l Female 115 165 g/l 7 days 140-186 g/l 8 days 3
More informationSerodos and Serodos plus
Design Verification Serodos and Serodos plus Contents 1 Value Adjustment... 2 2 Target Determination... 2 3 Stability... 2 Real-Time Stability... 3 Stability after Reconstitution... 4 Stability after Reconstitution
More informationWhy Traceability Matters to Patients?
Why Traceability Matters to Patients? (and you are all patients) Graham Jones Department of Chemical Pathology St Vincent s Hospital, Sydney JCTLM Members and Stakeholders meeting, Paris 2017 Acknowledgements
More informationAssessment of latest LFT guidelines from American College of Gastroenterology. Gus Koerbin
Assessment of latest LFT guidelines from American College of Gastroenterology Gus Koerbin Focus on ALT Review AACB current recommendations RI (examples) Bias Clinical Significance BMI AGC Guidelines Response
More informationWSLH. Calibration Verification/ Linearity Products. roficiency. esting. Products provided in partnership with:
WSLH PT roficiency esting Calibration Verification/ Linearity Products Products provided in partnership with: www.wslhpt.org 800-462-5261 PTService@slh.wisc.edu General Chemistry Ammonia/Ethanol - 5 x
More informationVITROS MicroSlide Assay Summary
ACET Acetaminophen ALB Albumin EDTA 10 9 TDM PV Specialty 5.5 4 PV Isotonic saline or 10 200 μg/ml 66 1323 μmol/l (μmol/l = μg/ml x 6.616) 1.00 6.00 g/dl 10.0-60.0 g/l (g/l = g/dl x 10) Therapeutic: 670
More informationCan We Now Recommend a Common Calculation for Osmolar Gap?
Can We Now Recommend a Common Calculation for Osmolar Gap? Oral Presentation AACB 4 th Harmonisation Workshop, Sydney, May 2015 Dr James Doery INTRODUCTION What is the osmolal gap? Why measure? Clinical
More informationQuestionnaire. Traceability in EQA. Traceability
Questionnaire in EQA QUESTIONNAIRE ON TRACEABILITY QUESTIONNAIRE ON TRACEABILITY GENERAL INFORMATION Name EQA organisation Country Specify the total number of measurands in the schemes of your EQA organisation
More informationNORMAL LABORATORY VALUES FOR CHILDREN
Pediatric Drug Lookup Normal Laboratory Values for NORMAL LABORATORY VALUES FOR CHILDREN CHEMISTRY Normal Values Albumin 0-1 y 2.0-4.0 g/dl 1 y to adult 3.5-5.5 g/dl Ammonia Newborns 90-150 mcg/dl 40-120
More informationHamilton Regional Laboratory Medicine Program
Created: April 2002 of Review: February 2004 of Review: June 2006 of Review: July 2007, St. Joseph s Healthcare went live with Meditech as of June18, 2007. of Review: August 2009 of Review: December 2011;
More informationComparison of VACUETTE Heparin Gel Tubes for Common Chemistry Analytes
Comparison of VACUETTE Heparin Gel Tubes for Common Chemistry Analytes Background: Greiner-Bio-One, Austria has been selling plastic evacuated tubes (VACUETTE ) for venous blood collection since 9. The
More informationTRENDS IN TIME. EXTERNAL EVALUATION PROGRAM FOR Immmunoassays - Chemistry
Commissie voor Klinische Biologie Commission de Biologie Clinique EXTERNAL EVALUATION PROGRAM FOR Immmunoassays - Chemistry TRENDS IN TIME CM Van Campenhout N Hamers JC Libeer WIV/ISP/IPH Clinical Biology
More informationStability of VACUETTE Lithium Heparin Separator tubes with modified centrifugation conditions
Stability of VACUETTE Lithium Heparin Separator tubes with modified centrifugation conditions Background: Greiner-Bio-One, Austria has been selling plastic evacuated tubes (VACUETTE ) for venous blood
More informationPaediatric reference intervals an update. Tina Yen Harmonisation Workshop Sydney 18 th May 2017
Paediatric reference intervals an update Tina Yen Harmonisation Workshop Sydney 18 th May 2017 Meeting of the AACB Paediatric SIG Tuesday 16 th May 2017 Prof Frank Bowling (NSW/ TAS) Prof Rita Horvath
More informationTables of Normal Values (As of February 2005)
Tables of Normal Values (As of February 2005) Note: Values and units of measurement listed in these Tables are derived from several resources. Substantial variation exists in the ranges quoted as normal
More informationAnalyte Specimen Demographic Reference Range Units
Acetone Negative titer Alanine aminotransferase (ALT/SGPT) 10-49 U/L Albumin 3.2-4.8 g/dl Alcohol < 10 Alpha-fetoprotein (AFP) < 1.3-8.1 ng/ml Alkaline phosphatase 0 7 days 7 30 days 1 3 3 6 6 12 1 3 3
More informationCERTIFICATE OF ACCREDITATION
CERTIFICATE OF ACCREDITATION In terms of section 22(2) (b) of the Accreditation for Conformity Assessment, Calibration and Good Laboratory Practice Act, 2006 (Act 19 of 2006), read with sections 23(1),
More informationHamilton Regional Laboratory Medicine Program
Created: April 2002 of Review: February 2004 of Review: June 2006 of Review: July 2007, St. Joseph s Healthcare went live with Meditech as of June18, 2007. of Review: August 2009 of Review: December 2011;
More informationPlease contact the Client Services Team if you require further information.
Reference ranges are quoted on all reports where appropriate for the test carried out. The reference range and reporting units, including any interpretive information, is specific to the methodology used
More informationLIQUID ASSAYED CHEMISTRY CONTROL PREMIUM PLUS - LEVEL 1 (LIQ CHEM ASY PREMIUM PLUS 1)
0086 LIQUID ASSAYED CHEMISTRY CONTROL PREMIUM PLUS - LEVEL 1 (LIQ CHEM ASY PREMIUM PLUS 1) CAT. NO. LAL 4213 LOT NO. 238UL SIZE: 12 x 5 ml EXPIRY: 2018-04-28 GTIN: 05055273209006 INTENDED USE This product
More informationCoping with Analytical Interferences
Coping with Analytical Interferences (Handling Icteric, Hemolytic and Lipaemic Samples) Graham Jones Department of Chemical Pathology St Vincent s Hospital, Sydney Surabaya Indonesia 2016 Acknowledgements
More informationRoyal College of Pathologists of Australasia Allowable Limits of Performance
The RCPA (Royal College of Pathologists of Australasia) have developed a thorough set of specifications for allowable error. For those not bound by the CLIA regulations, these can serve as a valuable resource.
More informationTraceability in External Quality Assessment: How Weqas ensures traceability in EQA and stresses its importance to users. David Ducroq.
Traceability in External Quality Assessment: How Weqas ensures traceability in EQA and stresses its importance to users David Ducroq Weqas Unit 6, Parc Tŷ Glas Llanishen Cardiff UK www.weqas.com Programme
More informationSydPath Reference Intervals for Clinical Trials (Contract Pathology Unit) Unauthorised Copy
HAEMATOLOGY APTT 1 150 M 25 35 sec APTT 1 150 F 25 35 sec Basophils Cord 2 weeks M 0.0 0.4 10^9/L Basophils Cord 2 weeks F 0.0 0.4 10^9/L Basophils 2 wks 3 mths M 0.0 0.2 10^9/L Basophils 2 wks 3 mths
More informationManufacturer Report for Siemens Unassayed Chemistry Lot Exp 30 Jun 2018
Acetaminophen Enzymatic, colorimetric µg/ml.09 0..0.09 0..0 0. 0. 0. 0. 9.. 9.0 0.9.0..9.. Albumin Bromcresol Purple (BCP) g/dl.0 0.0..0 0.00.. 0.0.. 0.09..9 0.0..9 0.0..0 0.0..0 0.0. Alkaline Phosphatase
More informationExternal Quality Assessment for Calibration Laboratories in Laboratory Medicine - RELA -
External Quality Assessment for Calibration Laboratories in Laboratory Medicine - RELA - Anja Kessler Bonn, Germany 1 RELA Surveys www.dgkl-rfb.de 2 RELA Annual Process Each participant receives two different
More informationSeeing is not Believing (13-Nov-2004)
In: 55th Annual Meeting of the American College of Veterinary Pathologists (ACVP) & 39th Annual Meeting of the American Society of Clinical Pathology (ASVCP), ACVP and ASVCP (Eds.) Publisher: American
More informationBiochemistry Adult Reference Ranges
Certified correct on 28/06/2016 Biochemistry Adult Reference Ranges Test Reference range Units Reference range from Traceable to standard reference material Albumin 35 50 g/l Pathology IRMM ERM-DA470k/IFCC
More informationEvaluation of new MiniCollect Z Serum (Separator) Tubes
Evaluation of new MiniCollect Z Serum (Separator) Tubes Background: Greiner Bio-One has developed a newly designed MiniCollect tube offering an integrated collection scoop. The advantage of the new tube
More informationProvided by MedicalStudentExams.com NORMAL LABORATORY VALUES
NORMAL LABORATORY VALUES 1. BLOOD, PLASMA, SERUM 2. CEREBROSPINAL FLUID 3. HEMATOLOGIC 4. SWEAT 5. URINE 6. SYNOVIAL FLUID 7. TOXIC LEVELS 8. Tumour Markers 9. Differential of Cerebral Spinal Fluid 10.
More information10 Essential Blood Tests PART 1
Presents 10 Essential Blood Tests PART 1 The Blood Chemistry Webinars With DR. DICKEN WEATHERBY Creator of the Blood Chemistry Software Essential Blood Test #1: Basic Chem Screen and CBC http://bloodchemsoftware.com
More informationThe analytical phase
The analytical phase Result interpretation Test request Result Sampling Black box: the lab ANALYTICAL PHASE The CASE Uncle Pete, 67 years old Marked abdominal pain 8 pm, ED Acute abdomen? Assessment (+
More informationENROLLMENT CONFIRMATION
Step 1: Please review the Facility/Contact information. If any of the information is incorrect, please make the appropriate changes below: Facility/Contact Phone: (850)474-3660 Fax: (850)474-3659 6431
More informationMEMORANDUM. These reference ranges are effective immediately but sample requirements remain unchanged currently.
MEMORANDUM Originating Department Chemical Pathology Issued By: Issued To: Subject: Details: Dr. Shari Srinivasan All Laboratory Service Users Change in Chemical Pathology Analysers Dear Colleague, As
More informationHUMAN ASSAYED MULTI-SERA - LEVEL 2 (HUM ASY CONTROL 2)
0843 HUMAN ASSAYED MULTI-SERA - LEVEL 2 (HUM ASY CONTROL 2) CAT. NO. HN1530 / HS2611 LOT NO. 899UN SIZE: 20 x 5ml / 5 x 5ml EXPIRY: 2018-02 INTENDED USE This product is intended for in vitro diagnostic
More informationControls & Calibrators Clinical Chemistry
Controls & Calibrators Clinical Chemistry Clinical Chemistry Controls & Lipids Clinical Chemistry and lipid quality controls have been manufactured from true human serum to ensure they perform the same
More informationEvaluation Report of the Pneumatic Tube Transport System (PEVCO) connecting Dialysis Hospital to. Mubarak Hospital. Dr.
5 Evaluation Report of the Transport System (PEVCO) connecting Dialysis Hospital to Mubarak Hospital Dr. Anwar AlAnjeri Senior Registrar Clinical Biochemistry Laboratory Mubarak Hospital Introduction:
More informationUpdate: Body Fluid Testing. Fernando San Gil
Update: Body Fluid Testing Fernando San Gil Background Notes - 1 Year Significant moments in IVD 2013 NATA and the TGA publish new validation and registration requirements for in-house IVDs and for in-house
More informationSchedule of Accreditation issued by United Kingdom Accreditation Service 2 Pine Trees, Chertsey Lane, Staines-upon-Thames, TW18 3HR, UK
2 Pine Trees, Chertsey Lane, Staines-upon-Thames, TW18 3HR, UK Tameside and Glossop Integrated Care NHS Foundation Trust Department of Blood Sciences Tameside General Hospital New Fountain House Ashton-under-Lyne
More informationGlobal Report #01 27/11/2013. Patient percentile monitoring compared to internal quality control (IQC) monitoring
Patient Percentile Monitoring Global Report #01 CONTENT Project status Patient percentile monitoring compared to internal quality control (IQC) monitoring Comparison of outpatient/all patient monitoring
More informationDR. Miswar Fattah, SSi, MSi Makassar, 6 th June Education. Current position
DR. Miswar Fattah, SSi, MSi Makassar, 6 th June 1978 Education 1997 : SMAK Depkes Makassar 2002 : Chemistry - UNHAS 2006 : Master of Science in Clinical Chemistry, Biomedicine- UNHAS 2012 : Doctor of Medicine
More informationCALIBRATION SERUM LEVEL 3 (CAL 3)
CALIBRATION SERUM LEVEL 3 (CAL 3) CAT. NO. CAL 2351 LOT NO. 907UE SIZE: 20 x 5ml EXPIRY: 2019-07-28 GTIN: 05055273200966 INTENDED USE For use as a Calibrator in clinical chemistry assays. RANDOX Calibration
More informationHUMAN ASSAYED MULTI-SERA - LEVEL 2 (HUM ASY CONTROL 2)
0120 HUMAN ASSAYED MULTI-SERA - LEVEL 2 (HUM ASY CONTROL 2) CAT. NO. HN1530 / HS2611 LOT NO. 995UN SIZE: 20 x 5ml / 5 x 5ml EXP: 2018-12 INTENDED USE This product is intended for in vitro diagnostic use,
More informationGENERAL. Compulsory module GEN II Example questions (Acute and Routine Clinical Chemistry)
GENERAL Compulsory module GEN II Example questions (Acute and Routine Clinical Chemistry) ESSAY ANSWER QUESTIONS 2 Questions - each question is worth 35 marks.all questions should be attempted Question
More informationInspector's Accreditation Unit Activity Menu
01/12/20XX 15:58:57 Laboratory Accreditation Program Page 1 of 9 CHEMISTRY 1501 ALT, serum/plasma 1502 Albumin, serum/plasma 1504 Alkaline phosphatase, serum/plasma 1506 Amylase, serum/plasma 1508 Bilirubin,
More informationTypes of target values, acceptable ranges
Types of target values, acceptable ranges As the differential of rounding, maximum 1 percent point deviation is allowed from the maximum acceptable range. 100. Clinical chemistry (wet) 1. Calcium RMV 10
More informationCALIBRATION SERUM - LEVEL 2 (CAL 2)
CAT. NO. CAL 2350 LOT NO. 1242UN SIZE: 20 x 5ml EXPIRY: 2020-02-28 GTIN: 05055273200959 INTENDED USE For use as a Calibrator in clinical chemistry assays. RANDOX Calibration Sera are based on lyophilised
More informationCALIBRATION SERUM LEVEL 3 (CAL 3)
CALIBRATION SERUM LEVEL 3 (CAL 3) CAT. NO. CAL 2351 LOT NO. 709UE SIZE: 20 x 5ml EXP: 2016-12 INTENDED USE For use as a Calibrator in clinical chemistry assays. RANDOX Calibration Sera are based on lyophilised
More informationRapid Laboratories In House Tests
Electrolytes CL CL (CHLORIDE) Electrolytes CO2 CO2 (BICARBONATE) Electrolytes K K (POTASSIUM) Electrolytes NA NA (SODIUM) Basic Metabolic Panel (BMP) GLU GLU (GLUCOSE) Basic Metabolic Panel (BMP) CA CA
More informationHUMAN ASSAYED MULTI-SERA - LEVEL 2 (HUM ASY CONTROL 2)
0086 HUMAN ASSAYED MULTI-SERA - LEVEL 2 (HUM ASY CONTROL 2) CAT. NO. HN1530 GTIN: 05055273203783 SIZE: 20 x 5ml CAT. NO. HS2611 GTIN: 05055273203813 SIZE: 5 x 5ml LOT NO. 1089UN EXPIRY: 2020-02-28 INTENDED
More informationDIABETES AND LABORATORY TESTS. Author: Josephine Davis
DIABETES AND LABORATORY TESTS Author: Josephine Davis LAB TESTS Think twice before you test. What is the reason for testing? Laboratory tests are generally requested in primary care for one of the following
More informationFullerton Healthcare Screening Centres
Fullerton Healthcare Screening Centres Fullerton Healthcare Screening Centre @ Ngee Ann City The Penthouse, #26-02 Ngee Ann City Tower B, 391B Orchard Road, Singapore 238874 Operating hours: Monday - Friday
More informationLaboratory Medicine Standardization Activity in Japan
JCTLM 15/11/2005 Sevres, Paris oratory Medicine Standardization Activity in Japan National Institute Metrology of Japan (NMIJ) Koichi Chiba Fujirebio Inc. Katsuhiko Yamamoto University of Tsukuba Katsuhiko
More informationS Potassium K mmol/l Up to 1m m - 1y >1y /07/2010. S Chloride CL mmol/l Up to 3m > 3m /07/2010
Northumbria Healthcare NHS Trust Clinical Chemistry Deartment Reference Ranges Reference Ranges in use in Telepath Laboratory System at July 2005 unless indicated otherwise Last date Amended; 20/08/2010
More informationHUMAN ASSAYED MULTI-SERA - LEVEL 3 (HUM ASY CONTROL 3)
0086 HUMAN ASSAYED MULTI-SERA - LEVEL 3 (HUM ASY CONTROL 3) CAT. NO. HE1532 / HS2611 LOT NO. 789UE SIZE: 20 x 5ml / 5 x 5ml EXP: 2019-05 INTENDED USE This product is intended for in vitro diagnostic use
More informationBiochemistry Department Laboratory Handbook
Biochemistry Department Laboratory Handbook Version : 3.3 Page 1 of 12 Table of contents Biochemistry Department... 1 Laboratory Handbook... 1 Introduction... 3 The Biochemistry Department... 3 High risk
More informationREFERENCE INTERVALS. Units Canine Feline Bovine Equine Porcine Ovine
REFERENCE INTERVALS Biochemistry Units Canine Feline Bovine Equine Porcine Ovine Sodium mmol/l 144-151 149-156 135-151 135-148 140-150 143-151 Potassium mmol/l 3.9-5.3 3.3-5.2 3.9-5.9 3.0-5.0 4.7-7.1 4.6-7.0
More informationCERTIFICATE OF ACCREDITATION
CERTIFICATE OF ACCREDITATION In terms of section 22(2) (b) of the Accreditation for Conformity Assessment, Calibration and Good Laboratory Practice Act, 2006 (Act 19 of 2006), read with sections 23(1),
More informationCOMPANY OR UNIVERSITY
CONTRIBUTOR NAME Daniel Heinrich, DVM CONTRIBUTOR EMAIL dheinric@umn.edu COAUTHORS Jed Overmann, DVM, DACVP; Davis Seelig DVM, PhD, DACVP & Matthew Sturos, DVM COMPANY OR UNIVERSITY University of Minnesota
More informationOnline catalog
This catalog contains information about tests performed at Green Clinic Laboratory. For samples to be sent to Quest Diagnostics or any other reference lab please contact the Green Clinic Laboratory (318-251-6378)
More informationcobas c 501 analyzer and cobas c 311 analyzer Within Run Imprecision Guidelines
cobas c 501 analyzer and cobas c 311 analyzer General Information How to use these guidelines Unless otherwise indicated, the data presented is the same for both the cobas c 501 analyzer and the cobas
More informationAustralian and New Zealand College of Veterinary Scientists. Membership Examination. Veterinary Pathology Paper 1
Australian and New Zealand College of Veterinary Scientists Membership Examination June 2014 Veterinary Pathology Paper 1 Perusal time: Fifteen (15) minutes Time allowed: Two (2) hours after perusal Answer
More informationTotal Cost of Ownership (TCO): An evidence-based approach to compare laboratory equipment
Total Cost of Ownership (TCO): An evidence-based approach to compare laboratory equipment P.C.G. Gontard 1, L.I. Stankevich 1, B.G. Gorodetsky 1 SUMMARY Clinical laboratories across the globe operate in
More informationAustralian and New Zealand College of Veterinary Scientists. Membership Examination. Small Animal Medicine Paper 1
Australian and New Zealand College of Veterinary Scientists Membership Examination June 2017 Small Animal Medicine Paper 1 Perusal time: Fifteen (15) minutes Time allowed: Two (2) hours after perusal Answer
More informationBC Biomedical Laboratories Adult Reference Ranges
BC Biomedical Laboratories Adult s Name Age 25 OH VITAMIN D Blood B 0-100 nmol/l Interpretation: < 25 Deficient 25-74 Insufficient 75-199 Sufficient > 200 Toxic 5HIAA (CALC) Urine B 0-100
More informationBASIC METABOLIC PANEL
Update 2/12/2018 BASIC METABOLIC PANEL CPT 80048 Stability: 3 days at 15-25 C; 7 days at 2-8 C; > 7 days at -70 C Colorimetric Assay, Rate reaction, ISE Components: BUN, Calcium, Chloride, CO2, Creatinine,
More informationVenous Blood Gas Reference Intervals
Venous Blood Gas Reference Intervals The NSW Health Pathology approach Andrea Rita Horvath Department of Clinical Chemistry & Endocrinology NSW Health Pathology, Prince of Wales Hospital, Sydney andrea.horvath@health.nsw.gov.au
More informationHarmonizing Reference Intervals (hris) ± Result Uncertainty (RU)
Harmonizing Reference Intervals (hris) ± Result Uncertainty (RU) What do you think the main concerns will be for harmonized reference intervals in your lab? How can we do a better job of conveying what
More informationSchedule of Accreditation issued by United Kingdom Accreditation Service 2 Pine Trees, Chertsey Lane, Staines-upon-Thames, TW18 3HR, UK
2 Pine Trees, Chertsey Lane, Staines-upon-Thames, TW18 3HR, UK Spire Portsmouth Hospital Bartons Road Havant PO9 5NP United Kingdom Contact: Natalie Peck E-Mail: natalie.peck@spirehealthcare.com Website:
More informationSchedule of Accreditation issued by United Kingdom Accreditation Service 2 Pine Trees, Chertsey Lane, Staines-upon-Thames, TW18 3HR, UK
2 Pine Trees, Chertsey Lane, Staines-upon-Thames, TW18 3HR, UK Biochemistry Department Poole Hospital Longfleet Road Poole BH15 2JB Contact: Dr Fergus Jack Tel: +44 (0) 1202 442 497 E-Mail: Fergus.jack@poole.nhs.uk
More informationAdams Memorial Hospital Decatur, Indiana EXPLANATION OF LABORATORY TESTS
Adams Memorial Hospital Decatur, Indiana EXPLANATION OF LABORATORY TESTS Your health is important to us! The test descriptions listed below are for educational purposes only. Laboratory test interpretation
More informationDr Bill Bartlett Blood Sciences, Ninewells Hospital & Medical School, NHS Tayside, Scotland, UK.
Dr Bill Bartlett Blood Sciences, Ninewells Hospital & Medical School, NHS Tayside, Scotland, UK. Bill.Bartlett@nhs.net www.biologicalvariation.com Biological variation affects the clinical utility of reference
More informationAustralian and New Zealand College of Veterinary Scientists. Fellowship Examination. Veterinary Clinical Pathology Paper 1
Australian and New Zealand College of Veterinary Scientists Fellowship Examination June 2012 Veterinary Clinical Pathology Paper 1 Perusal time: Twenty (20) minutes Time allowed: Three (3) hours after
More informationCERTIFICATE OF ACCREDITATION
CERTIFICATE OF ACCREDITATION In terms of section 22(2) (b) of the Accreditation for Conformity Assessment, Calibration and Good Laboratory Practice Act, 2006 (Act 19 of 2006), read with sections 23(1),
More informationCLINICAL CHEMISTRY REAGENTS. Product Profile
Product Profile Why Clinical Chemistry Reagents? Quantitative determination of specific analytes associated with various types of disease. Diagnosis Identifying a disease already present Prognosis Forecasting
More informationTest Profiles Time for a Change. Tony Badrick (AACB Harmonisation Committee)
Test Profiles Time for a Change Tony Badrick (AACB Harmonisation Committee) 1. Why Profiles 2. Profiles A. LFT B. Electrolyte C. Renal D. Bone 3. Summary Same clothes!! Harmonisation! Same car!! Harmonisation!
More information1.) 3 yr old FS Siamese cat: 3 day history of lethargy, anorexia. Dyspneic, thin, febrile.
1.) 3 yr old FS Siamese cat: 3 day history of lethargy, anorexia. Dyspneic, thin, febrile. NUCLEATED CELLS 19.5 High 4.0-14.0 x 10^3/ul METAMYELOCYTES 9 % 1.8 High 0.0-0.0 x 10^3/ul BAND NEUTROPHILS 61
More informationThe positive side of overdiagnosis
The positive side of overdiagnosis Does an immediate comprehensive panel of laboratory tests in outpatient care improve patient outcomes? Bram Vrijsen, Maarten ten Berg, Christiana Naaktgeboren, Jolande
More informationEvidence Based HbA1c Accuracy. Sabrina Koetsier Medical Scientist RCPAQAP Chemical Pathology
Evidence Based HbA1c Accuracy Sabrina Koetsier Medical Scientist RCPAQAP Chemical Pathology Fresh lycohaemoglobin This program is designed to assist laboratories to assess the accuracy of their hihba1c
More informationREFERENCE INTERVALS OF COMMON CLINICAL CHEMISTRY ANALYTES FOR ADULTS IN HONG KONG
The Journal of the International Federation of Clinical Chemistry and Laboratory Medicine CHEMISTRY ANALYTES FOR ADULTS IN HONG KONG YC Lo 1, David A. Armbruster 2 1 Pamela Youde Nethersole Eastern Hospital,
More information