1.) 3 yr old FS Siamese cat: 3 day history of lethargy, anorexia. Dyspneic, thin, febrile.

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1 1.) 3 yr old FS Siamese cat: 3 day history of lethargy, anorexia. Dyspneic, thin, febrile. NUCLEATED CELLS 19.5 High x 10^3/ul METAMYELOCYTES 9 % 1.8 High x 10^3/ul BAND NEUTROPHILS 61 % 11.9 High x 10^3/ul SEG NEUTROPHILS 12 % x 10^3/ul LYMPHOCYTES 8 % x 10^3/ul MONOCYTES EOSINOPHILS 2 % x 10^3/ul nrbcs 1 % 0.2 High x 10^3/ul MYELO 5 % 1.0 High x 10^3/ul BLAST 2 % 0.4 High x 10^3/ul PLASMA PROTEIN g/dl RBC x 10^6/ul HGB g/dl PCV % MCV fl MCHC g/dl RDW CLUMPED PLATELETS

2 1.) 3 yr old FS Siamese cat: 3 day history of lethargy, anorexia. Dyspneic, thin, febrile. GLUCOSE MG/DL BUN MG/DL CREATININE 0.7 Low MG/DL PHOSPHORUS MG/DL CALCIUM MG/DL TOTAL PROTEIN GM/DL ALBUMIN 1.7 Low GM/DL GLOBULIN 5.9 High GM/DL A/G RATIO 0.3 Low RATIO CHOLESTEROL MG/DL T_BILIRUBIN 4.4 High MG/DL CK 457 High IU/L ALP 6 Low IU/L ALT IU/L AST 206 High IU/L GGT IU/L SODIUM MEQ/L POTASSIUM MEQ/L CHLORIDE 112 Low MEQ/L BICARBONATE (HC03-) MEQ/L ANION GAP CALC CALC. OSMOLALITY mosm/kg

3 1.) 3 yr old FS Siamese cat: 3 day history of lethargy, anorexia. Dyspneic, thin, febrile. Arterial po2 = 56 (73-92) Thoracic Radiographs: Large volume of pleural fluid Thoracic fluid: 140,000 cells/µl >95% poorly preserved neutrophils 4.2 gm/dl protein Large numbers of a mixed bacterial population -Culture: 3+ Pasteurella multocida 3+ Fusobacterium 3+ Prevotella bivia

4 2.) 18 yr old FS DSH cat: Wt loss, vomiting. NUCLEATED CELLS 20.6 High x 10^3/ul BAND NEUTROPHILS x 10^3/ul SEG NEUTROPHILS 83 % 17.1 High x 10^3/ul LYMPHOCYTES 6 % 1.2 Low x 10^3/ul MONOCYTES 1 % x 10^3/ul EOSINOPHILS 10 % 2.1 High x 10^3/ul BASOPHILS x 10^3/ul nrbcs x 10^3/ul PLASMA PROTEIN g/dl RBC 4.6 Low x 10^6/ul HGB 8.3 Low g/dl PCV 26.0 Low % MCV 57.0 High fl MCHC g/dl RETICULOCYTES 0.4 % 18, #/ul CELL HEMOGLOGIN-RETIC pg MEAN CELL VOLUME-RETIC fl RDW 21.8 High PLATELETS Low x 10^3/ul

5 2.) 18 yr old FS DSH cat: Wt loss, vomiting. GLUCOSE MG/DL BUN 38 High MG/DL CREATININE 3.9 High MG/DL PHOSPHORUS MG/DL CALCIUM MG/DL MAGNESIUM MG/DL TOTAL PROTEIN GM/DL ALBUMIN GM/DL GLOBULIN GM/DL A/G RATIO RATIO CHOLESTEROL MG/DL T_BILIRUBIN MG/DL CK IU/L ALP IU/L ALT IU/L AST IU/L GGT IU/L SODIUM MEQ/L POTASSIUM MEQ/L CHLORIDE 127 High MEQ/L BICARBONATE (HC03-) MEQ/L ANION GAP CALC CALC. OSMOLALITY mosm/kg URINE SPECIFIC GRAVITY = 1.021

6 2.) 18 yr old FS DSH cat: Wt loss, vomiting. Mesenteric Lymphadenopathy -Aspirate: Possible small cell lymphoma -PCR for antigen receptor rearrangements (PARR): + T cell FeLV/FIV: Negative Cobalamin: = 99 ng/l ( ng/l) Folate: = 6.9 µg/l ( µg/l)

7 3.) 6 yr old MC Labrador Retriever: Acute onset lethargy. NUCLEATED CELLS 0.7 Low x 10^3/ul BAND NEUTROPHILS 12 % x 10^3/ul SEG NEUTROPHILS 12 % 0.1 Low x 10^3/ul LYMPHOCYTES 60 % 0.4 Low x 10^3/ul MONOCYTES 16 % 0.1 Low x 10^3/ul nrbcs PLASMA PROTEIN g/dl RBC 5.0 Low x 10^6/ul HGB 12.3 Low g/dl PCV 35.0 Low % MCV fl MCHC g/dl RETICULOCYTES 1.0 % 50, #/ul CELL HEMOGLOGIN-RETIC pg MEAN CELL VOLUME-RETIC fl RDW 15.9 High PLATELETS 29.0 Low x 10^3/ul

8 3.) 6 yr old MC Labrador Retriever: Acute onset lethargy. GLUCOSE MG/DL BUN 61 High 7-32 MG/DL CREATININE 3.2 High MG/DL PHOSPHORUS MG/DL CALCIUM 15.7 High MG/DL MAGNESIUM MG/DL TOTAL PROTEIN GM/DL ALBUMIN GM/DL GLOBULIN GM/DL A/G RATIO RATIO CHOLESTEROL MG/DL T_BILIRUBIN MG/DL CK IU/L ALP IU/L ALT IU/L AST 74 High IU/L GGT IU/L SODIUM MEQ/L POTASSIUM MEQ/L CHLORIDE MEQ/L BICARBONATE (HC03-) MEQ/L ANION GAP CALC IONIZED CALCIUM = 1.6 mm/l ( mm/l)

9 3.) 6 yr old MC Labrador Retriever: Acute onset lethargy. Urinalysis Value Item Color Yellow Clarity Clear USG ph 5.0 Protein SSA Protein Glucose Ketones Bilirubin 1+ Blood Exp. Value Negative Neg. Not done Neg. Negative Neg. Negative Neg. Neg. (0-1+ Normal in dogs) Negative Neg. Urine Sediment Item Value Squamous None Transit/ Rare Renal WBC Rare RBC Rare Casts None: None Crystals Calcium Oxalate Dihydrate: Moderate Bacteria None: None Sperm Negative Fat Few

10 4.) 4 yr old MC Dachshund: 3 days of vomiting. NUCLEATED CELLS 24.4 High x 10^3/ul SEG NEUTROPHILS 83 % 20.3 High x 10^3/ul LYMPHOCYTES 2 % 0.5 Low x 10^3/ul MONOCYTES 15 % 3.7 High x 10^3/ul PLASMA PROTEIN g/dl RBC 9.8 High x 10^6/ul HGB 21.0 High g/dl PCV 61.0 High % MCV fl MCHC g/dl RDW PLATELETS x 10^3/ul

11 4.) 4 yr old MC Dachshund: 3 days of vomiting. GLUCOSE 141 High MG/DL BUN 138 High 7-32 MG/DL CREATININE 4.5 High MG/DL PHOSPHORUS 13.9 High MG/DL CALCIUM MG/DL TOTAL PROTEIN 9.1 High GM/DL ALBUMIN 4.8 High GM/DL GLOBULIN 4.3 High GM/DL A/G RATIO RATIO CHOLESTEROL 466 High MG/DL T_BILIRUBIN 0.4 High MG/DL ALP 215 High IU/L ALT IU/L AST 65 High IU/L GGT IU/L SODIUM 136 Low MEQ/L POTASSIUM MEQ/L CHLORIDE 72 Low MEQ/L BICARBONATE (HC03-) 26.4 High MEQ/L ANION GAP 42 High CALC CALC. OSMOLALITY 318 High mosm/kg AMYLASE High IU/L LIPASE 1138 High IU/L URINE SPECIFIC GRAVITY = URINE ph = 5.0

12 5.) 3 yr old MC Belgian Shepard: Not eating 48 hrs., vomited 1x, T = 104 o NUCLEATED CELLS 17.5 High x 10^3/ul BAND NEUTROPHILS x 10^3/ul SEG NEUTROPHILS 17.0 High x 10^3/ul LYMPHOCYTES MONOCYTES x 10^3/ul PLASMA PROTEIN 8.2 RBC x 10^6/ul HGB g/dl PCV % MCV fl MCHC g/dl RETICULOCYTES 73,700 High #/ul CELL HEMO-RETIC 22.0 Low pg MCV-RETIC fl RDW PLATELETS Low x 10^3/ul MPV fl CLUMPED PLATELETS

13 5.) 3 yr old MC Belgian Shepard: Not eating 48 hrs., vomited 1x, T = 104 o GLUCOSE 66 Low MG/DL BUN MG/DL CREATININE MG/DL PHOSPHORUS 1.6 Low MG/DL CALCIUM MG/DL MAGNESIUM 2.7 High MG/DL TOTAL PROTEIN 7.3 High GM/DL ALBUMIN GM/DL GLOBULIN GM/DL A/G RATIO RATIO CHOLESTEROL 389 High MG/DL T_BILIRUBIN 8.2 High MG/DL CK 2023 High IU/L ALP 390 High IU/L ALT 4317 High IU/L AST 2126 High IU/L GGT IU/L SODIUM 175 High MEQ/L POTASSIUM MEQ/L CHLORIDE 152 High MEQ/L BICARBONATE (HC03-) 9.0 Low MEQ/L ANION GAP CALC CALC. OSMOLALITY 340 High mosm/kg

14 5.) 3 yr old MC Belgian Shepard: Not eating 48 hrs., vomited 1x, T = 104 o URINALYSIS: Voided USG ph 9.0 Protein 1+ (30 mg/dl) SSA Protein 1+ Glucose 4+ (100 mg/dl) Ketones Negative Bilirubin 2+ Blood 3+ Urine Sediment Squamous Occasional Transit/Renal Occasional WBC None, RBC Rare Casts: Hyaline-Occasional, Granular-Occasional Crystals None Bacteria Cocci: Many Day 0 Day2 PRO TIME seconds APTT seconds

15 6.) 8 yr old FS Dalmation: PU/PD, anorexia, lethargy, acutely down in hindend NUCLEATED CELLS 16.8 High x 10^3/ul BAND NEUTROPHILS 8 % 1.3 High x 10^3/ul SEG NEUTROPHILS 80 % 13.4 High x 10^3/ul LYMPHOCYTES 8 % x 10^3/ul MONOCYTES 4 % x 10^3/ul PLASMA PROTEIN g/dl RBC x 10^6/ul HGB g/dl PCV % MCV fl MCHC g/dl RETICULOCYTES 0.7 % 52, #/ul CELL Hb-RETIC pg MCV-RETIC fl RDW PLATELETS Low x 10^3/ul MPV 17.6 High fl

16 6.) 8 yr old FS Dalmation: PU/PD, anorexia, lethargy, acutely down in hindend AT III 0 Pooled Control=123% GLUCOSE MG/DL BUN 53 High 7-32 MG/DL CREATININE 4.5 High MG/DL PHOSPHORUS 10.6 High MG/DL CALCIUM MG/DL MAGNESIUM MG/DL TOTAL PROTEIN 4.8 Low GM/DL ALBUMIN 1.7 Low GM/DL GLOBULIN GM/DL A/G RATIO 0.5 Low RATIO CHOLESTEROL 573 High MG/DL T_BILIRUBIN MG/DL CK High IU/L ALP 333 High IU/L ALT 179 High IU/L AST 649 High IU/L GGT IU/L SODIUM MEQ/L POTASSIUM MEQ/L CHLORIDE 108 Low MEQ/L HC MEQ/L ANION GAP 24 High 13-22

17 6.) 8 yr old FS Dalmation: PU/PD, anorexia, lethargy, acutely down in hindend USG ph 7.0 Protein 4+ Glucose Negative Ketones Negative Bilirubin Negative Blood 4+ Urine Sediment Squamous None Transit/Renal 1-4/hpf WBC Rare, RBC >250/hpf Casts: Hyaline-Occasional Crystals None URINE PROTEIN/CREATINE RATIO = 24.6 APTT = 19.1 ( sec) 12-15% Blood Severe

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