Table of Contents. Farming. Purity. Process Integrity. Customization. Consistent High Quality. Full Traceability

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2 Table of Contents Introduction...2 Vertical Integration Locations of CBD Receptors...5 PCR Products...6 Phytocannabinoid-Rich Hemp Oil...7 Nanoemulsion-Based Platform...8 Water-Soluble Technology...9 Zero-THC PCR Hemp Oil (PDS)...10 Water-Soluble Powder (PDS)...11 Water-Soluble Liquid (PDS)...12 HydroPCR (PDS)...13 PCR Softgels (PDS)...14 Advanced PCR Softgels With Curcumin (PDS)...15 Advanced PCR Softgels With Melatonin (PDS)...16 PCR Tinctures (PDS)...17 Balms (PDS)...18 Vape & E-Liquids (PDS)...19 Cosmeceuticals...20 Meet Our Chief Scientific Officer...21 Eye Serum (PDS)...22 Face Cream (PDS)...23 Body Lotion (PDS)...24 Pain Cream (PDS)...25 Animal Health Overview K9 Chews (PDS)...28 Hemp Pellets (PDS)...29 Animal Health FAQ Product Configurations...32 Disclaimer...33 Farming Purity Process Integrity Customization Consistent High Quality Full Traceability 1

3 Folium Biosciences Folium Biosciences is the largest vertically integrated grower, manufacturer, and bulk distributor of medicinal hemp-derived phytocannabinoids in the USA. Our company was founded in 2014 in Colorado Springs, Colorado and was one of the first companies in the United States to receive a legal license to grow, process and distribute industrial hemp. We are fully licensed and registered with the Colorado Department of Agriculture. All of our Phytocannabinoid-Rich (PCR) hemp is grown in full compliance under section 7606 of the 2014 Federal Farm Bill. At Folium Biosciences, we believe the best products start with the best ingredients. We know that not all hemp is created equal, and not all CBD is the same. This is why we grow our own proprietary strain of hemp that is naturally high in cannabinoids. Folium Biosciences hemp is derived from a unique medicinal hemp variety. Therefore, our hemp can provide the real health benefits of medicinal cannabis without the psychoactive effects of THC. Quality, Consistency, and Transparency is our business. Whether it is the hemp growing in the greenhouses and farmland, or the processing of our PCR hemp oil in our state of the art extraction and purification facility, we pride ourselves on quality, consistency, and transparency. Our vertical integration and rigorous quality control allow us to create the best products with the highest potencies and purity. We know how important it is to understand the entire supply chain and are dedicated to the transparency and integrity of the entire 'seed to sale' process. Industrial Hemp Grown for Fiber & Seeds vs PCR Hemp Grown by Folium (medicinal hemp) 2

4 Vertical Integration Farming Extraction & Purification Located in La Junta, Colorado Our unique genetics provide our customers with a competitive advantage in the global hemp-derived phytocannabinoid industry Our plants are not genetically modified Proprietary high cannabidiol (CBD)/ low THC cultivar Phytocannabinoid and terpenoid rich strain On-site chromatography testing and 3rd party batch testing ensures accurate levels of phytocannabinoids and confirms the absence of THC through our proprietary processes Preserve the full spectrum profile of non-psychoactive phytocannabinoids and synergistic compounds such as cannabigerol (CBG), cannabinol (CBN), cannabichromene (CBC), and over 40 naturally preserved terpenes The end result is the highest quality full spectrum hemp derived phytocannabinoid-rich oil that contains no solvents, no heavy metals, no pesticides and no THC Phytocannabinoid-Rich Hemp Full Plant Outdoor High CBD Harvest 3

5 Turn-Key Solution White label our products with your brand; ready to be sold direct to consumers We offer an array of formulated, tested and packaged finished products In-house product development team Unique and custom formulations Rigorous stability testing We ship domestically & internationally Formulation & Development Distribution 4

6 Locations of CBD Receptors CANNABINOID RECEPTORS & NON-RECEPTOR PATHWAYS MODULATE HOMEOSTASIS Endocrine system Heart & circulatory system Urinary system Brain & central nervous system Complete skeletal system Lungs & respiratory system Digestive system Reproductive system Muscular system Epidermis, dermis, & subcutaneous tissue Peripheral nervous system CANNABINOID RECEPTORS OF THE BRAIN EXPLAIN BENEFITS OF ENDOCANNABINOIDS Cerebellum Movement Basal Ganglia Movement Medulla Nausea and vomiting chemoreceptor Spinal cord Peripheral sensation including pain Cerebral cortex Higher cognitive function Hypothalamus Appetite Hippocampus Learning, memory and stress ENDOCANNABINOID NEURO MODULATION Presynaptic Neuron Cannabinoid Receptors Neurotransmitters Neurotransmitter Receptors Endocannabinoid Lipid precursor Postsynaptic Neuron 5

7 PCR Prodcuts White Label Products PCR Soft Gels PCR Formulated Tinctures PCR Balms Vape and E-Liquids Animal Health Products Cosmeceuticals Bulk Products PCR Hemp Oil HydroPCR Water-Soluble Powder Water-Soluble Liquid 6

8 Phytocannabinoid-Rich Hemp Oil CBD is 90% of all cannabinoids in the extract* Total terpenes range between 1 and 4% Cannabidiol (CBD) Cannabichromene (CBC) Cannabigerol (CBG) Cannabidiolic Acid (CBDA) H OH Cannabidiol (CBD) Cannabinol (CBN) H Minor Cannabinoids HO *Minor cannabinoids are reduced to trace levels in the Zero-THC PCR Hemp Oil Understanding Different CBD in the Market β-bisabolene β-caryophyllene d-limonene Camphene Linalool Myrcene Guaiol Cadinene α-pinene Farnesol Phytol δ-3-carene Eucalyptol P-Cymene β-farnesene α-humulene Nerolidol E-Farnesene Myrcene γ-terpinene β-maaliene α-gurjunene Aristolene α-bisabolol Isopulegol Calarene Terpinene Geraniol Folium s PCR Oil PCR (Phytocannabinoid-Rich) Hemp Oil with Zero-THC is golden amber in color and rich in phytocannabinoids, terpenes, and fatty acids, making it a full spectrum oil. Our PCR oil has a high concentration of CBD, when combined with the other synergistic compounds makes it the most precious hemp-derived oil on the market. CBD Isolate CBD (cannabidiol) Isolate is a single molecule from the hemp plant that endures heavy processing to achieve its purity. All other beneficial cannabinoids, terpenes, etc. are destroyed in the process. The final product is a White / Off-white powder and used in many products to provide CBD. Hemp Seed Oil Hemp Seed Oil is Green in color and does not contain phytocannabinoids. This oil is a popular food source due to the high content of protein and omega fatty acids. It s also a beneficial emollient for skin. Cannabis Oil Cannabis Oil or Hash is an oil similar to PCR, however, cannabis oil is dark green or brown and is traditionally created with a high THC content; this oil has psychoactive effects. 7

9 Nanoemulsion-Based Platform OH Folium's nanoemulsions are patent pending formulas that use optimized composition and a unique process to manufacture. The average size of our hemp oil droplet in this form is 25 nanometers, compared with nanometers that is usually obtained by using the industry standard liposomal delivery method. The small size of the Folium nanoemulsion hemp oil leads to a much larger surface area of the hemp oil droplets leading to much higher absorption in the bloodstream. Hemp oil nanoemulsions can also be used in a number of consumer products, including the cosmetic, pharmaceutical and food industries. Due to their thermodynamic stability, nanoemulsions do not lead to phase separation (oil separating from water), thus enabling the formulation of stable products. H O 25 Nanometer (AVG) Folium s Patent Pending Nano-Sized Microemulsion for Maximum Bioavailability Superior 50% Absorption Competitor Nanometer Liposomal Microemulsion (Competitor) Only 10% Absorption H OH H HO 8

10 Water-Soluble Technology We have several proprietary and patent pending PCR water-soluble options for our customers to choose from. Our water-soluble technology is used to create a liquid or a powder that results in cannabidiol that is water soluble and highly bioavailable. Pure phytocannabinoid-rich hemp oil that is added to water remains insoluble, and under physiological conditions, is not readily absorbed into the bloodstream. However, when our hemp oil is converted into a water-soluble liquid, it quickly goes into the solution, forming cannabinoid emulsion droplets with an average size of 25 nanometers, providing a high surface area for enhanced bioavailability. This results in a superior ingredient for our customers to formulate with. Our standard PCR water-soluble powder is a phytocannabinoid-rich (PCR) powder with 20% CBD, other minor phytocannabinoids, and terpenes. This proprietary formulation has been designed for optimum bioavailability and maximum absorption. It is intended for dissolution immediately prior to consumption and for manufacturing of semisolid/solid products. Our standard water-soluble liquid formula is made with PCR hemp oil and food grade emulsifiers. It contains 7.5% CBD for flavored beverage formulations and semisolid formulations, or 35% for cosmetic applications. Product Attributes Completely Water Soluble Highly Bioavailable Water-Soluble Powder is 20% Cannabidiol Water-Soluble Liquid is 35% Cannabidiol for Cosmetic Products Full Spectrum 9

11 Zero-THC PCR Hemp Oil PRODUCT DATA SHEET Product Description Active Ingredients Attributes Packaging Microbial Analysis Contaminant Analysis Our Zero-THC Phytocannabinoid Hemp Oil has all cannabinoids and terpenes naturally found in hemp except Delta 9-Tetrahydrocannabinol (THC). This nonpsychoactive product allows for the global distribution of our hemp oil into international markets that have zero tolerance for any levels of THC. Our extraction & purification process uses a proprietary and patented technology that preserves all the phytocannabinoids, terpenes, and plant lipids while eliminating unwanted THC and chlorophyll. Customers can customize our hemp oils to the desired potency and specifications. A rigorous testing scheme using chromatography and 3rd party testing is followed to ensure that the critical attributes of taste, color, potency, and purity consistently meet quality control specifications for making finished products. Phytocannabinoid-Rich Hemp Oil Phytocannabinoids up to 85% Full Spectrum Tetrahydrocannabinol (THC) Not Detected Bulk 24 Month Shelf Life Total Aerobic Count < 2,000 cfu/g Total Yeast and Mold < 200 cfu/g E. Coli = Negative Salmonella = Negative Heavy Metals: Not Detected (ND) Lead: ND Arsenic: ND Residual Solvents: ND Approved Terminology Non-GMO Manufactured in the USA Organically Grown Hemp Halal Kosher Infuse into your product line. This product is not intended to diagnose, treat, cure, or prevent any disease and has not been evaluated by the FDA. 10 Bulk Products

12 Water Soluble Powder PRODUCT DATA SHEET Product Description Active Ingredients Inactive Ingredients Attributes Packaging Microbial Analysis Contaminant Analysis Our standard water-soluble PCR powder contains 20% CBD, other minor phytocannabinoids, and terpenes. This proprietary formulation has been designed for optimum bioavailability and maximum absorption. The product is full spectrum water soluble powder with a light herb taste. It is intended for dissolution immediately prior to consumption and for manufacturing of semisolid/solid products. 20% Phytocannabinoid-Rich Hemp Oil Dextrin, Acacia Gum, Sunflower Lecithin, Vitamin E Completely Water Soluble Highly Bioavailable Zero-THC Manufacturing Ready Full Spectrum Bulk 18 Month Shelf Life Total Aerobic Count < 2,000 cfu/g Total Yeast and Mold < 200 cfu/g E. Coli = Negative Salmonella = Negative Heavy Metals: Not Detected (ND) Lead: ND Arsenic: ND Residual Solvents: ND Approved Terminology Manufactured in the USA Organically Grown Hemp Halal Kosher This product is not intended to diagnose, treat, cure, or prevent any disease and has not been evaluated by the FDA. 11 Water Soluble Bulk Products

13 Water Soluble Liquid Competitor Competitor Folium PRODUCT DATA SHEET Standard Oil Nanometer Liposomal Microemulsion 25 Nanometer (AVG) Folium s Patent Pending Nano-Sized Microemulsion for Maximum Bioavailability Product Description Active Ingredients Inactive Ingredients Attributes Packaging Microbial Analysis Contaminant Analysis Approved Terminology Nanoemulsion vs Liposomal Our patent pending water-soluble formulation is developed through our nanoemulsion technology platform. This technology transforms active compounds into nano-sized emulsions making them highly bioavailable and more permeable when applied to the skin. This proprietary formulation has been designed for optimum bioavailability and maximum absorption intended for cosmetics/personal care products. 35% Phytocannabinoid-Rich Hemp Oil Polysorbate Emulsifiers, Water Completely Water Soluble Highly Bioavailable Zero-THC Manufacturing Ready Full Spectrum Bulk 18 Month Shelf Life Total Aerobic Count < 2,000 cfu/g Total Yeast and Mold < 200 cfu/g E. Coli = Negative Salmonella = Negative Heavy Metals: Not Detected (ND) Lead: ND Arsenic: ND Residual Solvents: ND Manufactured in the USA Organically Grown Hemp Halal Kosher Folium's nanoemulsions are patent pending formulas that use optimized composition and a unique process to manufacture. The average size of our hemp oil droplet is 25 nanometers, compared with nanometers that is usually obtained by using the industry standard liposomal delivery method. The small size of the Folium nanoemulsion leads to a much larger surface area of the hemp oil droplets, leading to much higher absorption in the bloodstream. Hemp oil nanoemulsions can also be used in a number of consumer products, including the cosmetic, pharmaceutical and food industries. Due to their thermodynamic stability, nanoemulsions do not lead to phase-separation (oil separating from water), and thus enable the formulation of stable products. This product is not intended to diagnose, treat, cure, or prevent any disease and has not been evaluated by the FDA. 12 Water Soluble Bulk Products

14 HydroPCR PRODUCT DATA SHEET Product Description Active Ingredients Inactive Ingredients Attributes Packaging Approved Terminology Microbial Analysis Contaminant Analysis HydroPCR is a 4% PCR Hemp Oil Nanoemulsion from Folium Biosciences. Built with Nano-Enhanced Absorption Technology (NEAT), this fully water-soluble formula was designed to create ready-to- drink, shelf stable beverages and bottled water. It is made with full-spectrum THC-free hemp oil rich in phytocannabinoids and contains substantially reduced amounts of natural surfactants compared to previous technologies. The manufacturing process uses a patented technology that breaks down cannabinoids into nanoemulsions 70 nm in size. This state-of-the-art solution was designed with the following in mind: (1) Shelf stability: The plant lipids in HydroPCR s 4% PCR Hemp Oil Nanoemulsion play a crucial role in ensuring that the beverage to which it is added, remains shelf stable. This makes it a superior product (compared to isolate) as the plant lipids in the hemp oil slow down Ostwald ripening, leading to 18 months of shelf life of the final product. (2) Bioavailability: Employing NEAT the nano-sized cannabinoid emulsion droplets lead to a much higher surface area, enhancing absorption through sublingual, topical or intestinal routes. Also, the full-spectrum hemp oil ensures that the carrier lipids do not break down in the small intestine, resulting in higher bioavailability of the cannabinoids. (3) Safety: The natural emulsifiers (Quillaja saponaria saponins) used in HydroPCR are derived from the soap bark tree, and are organic, preservative free and Generally Recognized as Safe, GRAS. The very low ratio of cannabinoids to surfactants (approximately 1:1) ensures that only a few milligrams of emulsifiers are consumed with the cannabinoids, resulting in an exceptionally safe and efficacious product. 4% Phytocannabinoid-Rich Hemp Oil Natural Emulsifier, Glycerin Zero-THC Full Spectrum Profile Water Soluble Highly Bioavailable Manufacturing Ready Nano-Enhanced Absorption Technology Bulk 18 Month Shelf Life Temperature sensitive, should be stored at F for maximum shelf life. Manufactured in the USA Organically Grown Hemp Halal Kosher Total Aerobic Count < 2,000 cfu/g Total E. ColiYeast and Mold < 200 cfu/g = Negative Salmonella = Negative Heavy Metals: Not Detected (ND) Lead: ND Arsenic: ND Residual Solvents: ND Fish gelatin may be used as a processing aid. This product is not intended to diagnose, treat, cure, or prevent any disease and has not been evaluated by the FDA. 13 Water Soluble Bulk Products

15 PCR Softgels 10 mg 25 mg PRODUCT DATA SHEET Product Description Active Ingredients Inactive Ingredients Our Phytocannabinoid-Rich (PCR) Softgels are created with our patent pending water-soluble PCR hemp oil, along with other minor phytocannabinoids and naturally present terpenes. This product contains 10 mg or 25 mg of phytocannabinoids per dose and is designed to have optimum bioavailability. The patent-pending water-soluble formulation inside these softgels is composed of a nanoemulsion-based delivery system with cannabinoid emulsion droplets approximately 25 nanometers in size. The high surface area of cannabinoid droplets maximizes in-vivo absorption and the resulting bioavailability is 3-5 times higher than cannabinoids delivered in oil form. The enhanced and consistent absorption (despite fed vs. fasting state) leads to predictable biological response and improved efficacy. 10 mg or 25 mg Phytocannabinoid-Rich Hemp Oil 10 mg: Polysorbate Emulsifiers, Medium Chain Triglycerides, Beta Caryophyllene. Gelatin Shell: Bovine-derived Gelatin, Glycerin, Sorbitol, and Water 25 mg: Polysorbate Emulsifiers, Medium Chain Triglycerides (MCT), Beta-Caryophyllene. Gelatin Shell: Bovine-derived Gelatin, Glycerin, Sorbitol and Water, Artificial Coloring which includes Red 40, Red 3, Yellow 5, Yellow 6, Blue 1, Blue 2 Attributes Packaging Microbial Analysis Contaminant Analysis Approved Terminology Measurements Zero-THC Full Spectrum Profile Pharmaceutical Grade Bulk or Bottled 18 Month Shelf Life Total Aerobic Count < 2,000 cfu/g Total Yeast and Mold < 200 cfu/g E. Coli = Negative Salmonella = Negative Heavy Metals: Not Detected (ND) Lead: ND Arsenic: ND Residual Solvents: ND Manufactured in the USA Organically Grown Hemp Pharmaceutical Grade 5/16 1/2 Weight: 0.66 Grams This product is not intended to diagnose, treat, cure, or prevent any disease and has not been evaluated by the FDA. 14 White Label

16 Advanced PCR Softgels With Curucmin PRODUCT DATA SHEET Product Description Active Ingredients Inactive Ingredients Attributes Packaging Unique Claims Microbial Analysis Contaminant Analysis Approved Terminology Measurements Our Phytocannabinoid-Rich (PCR) Softgels with Curcumin are created with our patent pending water-soluble PCR hemp oil. This product contains 25 mg of phytocannabinoids and 10 mg of curcumin per dose and is designed to have maximum absorption and optimum bioavailability. The patent-pending water-soluble formulation inside these softgels is composed of a nanoemulsion-based delivery system with cannabinoid and curcumin emulsion droplets approximately 25 nanometers in size. The high surface area of cannabinoid and curcumin droplets maximizes in-vivo absorption and the resulting bioavailability is 3-5 times higher for CBD, and 100-times higher for curcumin than their natural oily form. The enhanced and consistent absorption (despite fed vs. fasting state) leads to predictable biological response. 25 mg Phytocannabinoid-Rich Hemp Oil & 10 mg Curcuminoids per Softgel Polysorbate Emulsifiers, Medium Chain Triglycerides (MCT) Oil, Beta-Caryophyllene. Gelatin Shell: Bovine-derived Gelatin, Glycerin, Sorbitol and Water and Artificial Coloring which includes Yellow 5, Yellow 6 Zero-THC Full Spectrum Profile Pharmaceutical Grade Bulk or Bottled 18 Month Shelf Life CBD and curcumin are in water-soluble nanoemulsion form, increasing bioavailability. Made with full spectrum oil. Total Aerobic Count < 2,000 cfu/g Total Yeast and Mold < 200 cfu/g E. Coli = Negative Salmonella = Negative Heavy Metals: Not Detected (ND) Lead: ND Arsenic: ND Residual Solvents: ND Manufactured in the USA Organically Grown Hemp Pharmaceutical Grade 5/16 1/2 Weight: 0.66 Grams This product is not intended to diagnose, treat, cure, or prevent any disease and has not been evaluated by the FDA. 15 White Label

17 Advanced PCR Softgels With Melatonin PRODUCT DATA SHEET Product Description Active Ingredients Inactive Ingredients Attributes Packaging Unique Claims Microbial Analysis Contaminant Analysis Approved Terminology Measurements The advanced water-soluble nanoemulsion softgels are designed to address specific conditions like insomnia and sleep disorders and is composed of water-soluble phytocannabinoid-rich hemp oil and melatonin in a microemulsion form. The nano-sized droplets of cannabidiol and melatonin make these botanical actives easy to absorb into the bloodstream. With 25 mg of PCR hemp oil and 1 mg of Melatonin per softgel, this formula is truly synergistic, leveraging multiple botanical actives through various pathways help accomplish better quality of sleep. 25 mg Phytocannabinoid-Rich Hemp Oil & 1 mg Melatonin per Softgel Polysorbate Emulsifiers, Medium Chain Triglycerides (MCT) Oil, Beta-Caryophyllene. Gelatin Shell: Bovine-derived Gelatin, Glycerin, Sorbitol and Water and Artificial Coloring which includes Blue 1, Yellow 5, Blue 2, Red 40 Zero-THC Full Spectrum Profile Pharmaceutical Grade Bulk or Bottled 18 Month Shelf Life CBD and melatonin are in water-soluble nanoemulsion form, increasing bioavailability. Made with full spectrum oil. Total Aerobic Count < 2,000 cfu/g Total Yeast and Mold < 200 cfu/g E. Coli = Negative Salmonella = Negative Heavy Metals: Not Detected (ND) Lead: ND Arsenic: ND Residual Solvents: ND Manufactured in the USA Organically Grown Hemp Pharmaceutical Grade 5/16 1/2 Weight: 0.66 Grams This product is not intended to diagnose, treat, cure, or prevent any disease and has not been evaluated by the FDA. 16 White Label

18 PCR Tinctures PRODUCT DATA SHEET Product Description Active Ingredients Inactive Ingredients Attributes Packaging Microbial Analysis Contaminant Analysis Approved Terminology Our Phytocannabinoid-Rich (PCR) Tincture products are created using our full spectrum hemp oil and diluted with hemp seed oil, grape seed oil, or medium chain triglycerides and can be custom designed with any of our PCR Hemp oils. These products are designed for sublingual application. Our PCR tinctures can also be formulated with specific isolated terpenes, terpene blends, as well as our water-soluble liquid. Phytocannabinoid-Rich Hemp Oil Medium Chain Triglycerides (MCT) and/or Hemp Seed Oil and/or Grape Seed Oil, Orange Oil or Lemon Oil or Peppermint Oil for flavor Available in 250 mg, 500 mg, 1000 mg, or 1500 mg Full Spectrum Profile Standard Flavor Options: Peppermint, Orange, Lemon, No Flavor Customizations Available Bulk or Bottled 18 Month Shelf Life Total Aerobic Count < 2,000 cfu/g Total Yeast and Mold < 200 cfu/g E. Coli = Negative Salmonella = Negative Heavy Metals: Not Detected (ND) Lead: ND Arsenic: ND Residual Solvents: ND Manufactured in the USA All Natural Organically Grown Hemp Halal Kosher This product is not intended to diagnose, treat, cure, or prevent any disease and has not been evaluated by the FDA. 17 White Label

19 Balms PRODUCT DATA SHEET Product Description Our Phytocannabinoid-Rich (PCR) Hemp Oil Balms, are created with beeswax and medium chain triglycerides as well as essential oils of your choice. Active Ingredients Inactive Ingredients Attributes Packaging Microbial Analysis Contaminant Analysis Approved Terminology % Phytocannabinoid-Rich Hemp Oil Beeswax, Medium Chain Triglycerides, Lavender Essential Oil and Eucalyptus Essential Oil Custom Formulations Available 1 oz available in 250 mg, 500 mg, or 1000 mg 2 oz available in 500 mg, 1000 mg, or 2000 mg 1 oz, & 2 oz Bulk 18 Month Shelf Life Total Aerobic Count < 2,000 cfu/g Total Yeast and Mold < 200 cfu/g E. Coli = Negative Salmonella = Negative Heavy Metals: Not Detected (ND) Lead: ND Arsenic: ND Residual Solvents: ND Manufactured in the USA Organically Grown Hemp This product is not intended to diagnose, treat, cure, or prevent any disease and has not been evaluated by the FDA. 18 White Label

20 Vape & E-Liquids PRODUCT DATA SHEET Product Description Our Phytocannabinoid-Rich (PCR) Hemp Oil Vape products are created with VG or MCT oil, and have been designed to have accurate dosing delivery with our zero-thc oil. Our extraction process uses the entire plant for a full spectrum oil, containing all phytocannabinoids and terpenes naturally found in hemp. Active Ingredients Attributes Packaging Microbial Analysis Contaminant Analysis % Phytocannabinoid-Rich Hemp Oil Custom Terpene Blends Full Spectrum Profile Custom Products Available Different Flavors Available 1 oz VG in 250 mg, 500 mg, or 1000 mg 1 ml MCT in 150 mg, 200 mg, or 250 mg Bulk or Bottled 18 Month Shelf Life Total Aerobic Count < 2,000 cfu/g Total Yeast and Mold < 200 cfu/g E. Coli = Negative Salmonella = Negative Heavy Metals: Not Detected (ND) Lead: ND Arsenic: ND Residual Solvents: ND Approved Terminology Manufactured in the USA Organically Grown Hemp This product is not intended to diagnose, treat, cure, or prevent any disease and has not been evaluated by the FDA. 19 White Label

21 Cosmeceuticals CBD Skincare and the Endocannabinoid System (ECS) The main physiological function of the cutaneous ECS is to constitutively control the proper and well-balanced proliferation, differentiation and survival, as well as immune competence and tolerance, of skin cells. The use of CBD internally or as a skin lotion, patch, or oil maintains this delicate balance and may prevent from pathological conditions and diseases of the skin (e.g. acne, seborrhea, allergic dermatitis, itch and pain, psoriasis, hair growth disorders, and systemic sclerosis). 20

22 Meet our Chief Scientific Officer Dr. Raj Gupta Chief Scientific Officer Folium Biosciences Dr. Gupta is a pharmaceutical scientist, in charge of product development, technical operations, and laboratory services at Folium. Prior to Folium, Dr. Gupta was Senior Director of Technical Operations at Guthy Renker, overseeing contract manufacturing sites and commercializing billion-dollar brands under Proactiv+ and Meaningful Beauty brands. Prior to Guthy Renker, Dr.Gupta was a Principal Life Sciences Consultant for Quintiles and Validant Consulting, responsible for implementing GMP processes and FDA-compliant quality practices across over-the-counter drugs and personal care companies. Prior to Quintiles/Validant Consulting. Dr.Gupta held key technical roles at Clorox. Dr. Gupta earned a Ph.D. in Analytical Chemistry, and an M.B.A. in Operations Management, both from the University of Massachusetts, Amherst. Dr. Gupta received his B.S. from Indian Institute of Technology, Kharagpur Cosmeceuticals

23 Eye Serum with 1% CBD PRODUCT DATA SHEET Product Description Active Ingredients Inactive Ingredients Attributes Directions Packaging Microbial Analysis Approved Terminology Our Eye Serum is designed to help your skin feel soft, but not oily. Absorb within minutes, this formula delivers CBD topically as well as into the bloodstream. For best results, use around eyes in combination with our Face Cream and Body Lotion. The unique formula with skin permeation agents improves the retention of cannabidiol onto and enhance permeation through the skin. The unique ability of cannabidiol to bind with the skin s endocannabinoid system helps it modulate, control, and influence the desirable attributes; contrast, pigmentation, hair health, hydration, and oil production. 1% Phytocannabinoid-Rich Hemp Oil Water/Aqua, Haloxyl (Aqua,Chrysin,Glycerin,N-Hydroxysuccinimide, Palmitoyl Tetrapeptide-7, Palmitoyl Tripeptide-1, Steareth-20), Propanediol, Saccharomyces Cerevisiae Extract, Sodium Polyacrylate, Aloe Barbadensis Leaf Juice, Sandalwood extract, Cucumber5 extract, Niacinamide (Vitamin B3), Trisodium EDTA, Phenoxyethanol, Caprylyl Glycol, Ethylhexylglycerin, Hexylene Glycol Zero-THC Bulk 18 Month Shelf Life Full Spectrum Profile Use every morning and/or night after you cleanse and tone. Place a pea-sized amount of Eye Serum onto fingertips and spread evenly around eyes using upward circular motions. Total Aerobic Count < 2,000 cfu/g Total Yeast and Mold < 200 cfu/g E. Coli = Negative Salmonella = Negative Manufactured in the USA This product is not intended to diagnose, treat, cure, or prevent any disease and has not been evaluated by the FDA. 22 Cosmeceuticals

24 Face Cream with 0.5% CBD PRODUCT DATA SHEET Product Description Active Ingredients Inactive Ingredients Attributes Directions Packaging Microbial Analysis Approved Terminology Our Phytocannabinoid-Rich (PCR) Face Cream with 0.5% CBD is perfect for all skin types. It is ph balanced and made with organic botanical ingredients to help the skin stay moisturized. The unique formula with skin permeation agents improves the retention of cannabidiol onto and enhance permeation through the skin. The unique ability of cannabidiol to bind with the skin s endocannabinoid system helps it modulate, control, and influence the desirable attributes; contrast, pigmentation, hair health, hydration, and oil production. 0.5% Phytocannabinoid-Rich Hemp Oil Water/Aqua, Sweet Almond oil, Glyceryl Stearate SE, Isopropyl Palmitate, C12-15 Alkyl Benzoate, Sucrose Acetate Isobutyrate, Cetyl Alcohol, Stearic Acid, Glyceryl Stearate, PEG-100 Stearate, Butyrospermum Parkii (Shea Butter) Fruit, Ashwagandha extract, Gotu Kola extract, Lotus extract, Panthenol (ProVitamin B5), Glycerin, Phenoxyethanol, Caprylyl Glycol, Ethylhexylglycerin, Hexylene Glycol, Xanthan gum, Propanediol, Trisodium EDTA, Dimethicone, Carbomer, Triethanolamine, Fragrance Zero-THC Bulk 18 Month Shelf Life Full Spectrum Profile Apply to face and neck every morning and/or night after you cleanse and tone, using upward circular motions. Total Aerobic Count < 2,000 cfu/g Total Yeast and Mold < 200 cfu/g E. Coli = Negative Salmonella = Negative Manufactured in the USA This product is not intended to diagnose, treat, cure, or prevent any disease and has not been evaluated by the FDA. 23 Cosmeceuticals

25 PCR Body Lotion with 0.3% CBD PRODUCT DATA SHEET Product Description Our Moisturizing Body Lotion is perfect for dry skin. The unique formula with skin permeation agents improve the retention of cannabidiol onto and enhance permeation through the skin. The unique ability of cannabidiol to bind with the skin s endocannabinoid system helps it modulate, control, and influence the desirable attributes; contrast, pigmentation, hair health, hydration, and oil production. Active Ingredients Inactive Ingredients Attributes Directions Packaging Microbial Analysis Approved Terminology 0.3% Phytocannabinoid-Rich Hemp Oil Water/Aqua, Isopropyl Palmitate, C12-15 Alkyl Benzoate, Sucrose Acetate Isobutyrate, C12-15 Alkyl Benzoate, Glycerin, Glyceryl Stearate, PEG-100 Stearate, Cetyl Alcohol, Triphala extract, Honey extract, Coconut extract, Tocopheryl Acetate (Vitamin E), Sodium PCA (NMF-Natural Moisturizing Factor), Stearic Acid, Xanthan gum, Trisodium EDTA, Dimethicone, Triethanolamine, Carbomer, Phenoxyethanol, Caprylyl Glycol, Ethylhexylglycerin, Hexylene Glycol, Fragrance Zero-THC Apply to full body including face, elbows and heels. Bulk 18 Month Shelf Life Total Aerobic Count < 2,000 cfu/g Total Yeast and Mold < 200 cfu/g E. Coli = Negative Salmonella = Negative Manufactured in the USA Full Spectrum Profile This product is not intended to diagnose, treat, cure, or prevent any disease and has not been evaluated by the FDA. 24 Cosmeceuticals

26 Pain Cream with 0.35% CBD PRODUCT DATA SHEET Product Description Our Pain Cream is designed as a skin analgesic, which also helps relieve joint pain. The unique formula with skin permeation agents improves the retention of cannabidiol onto and enhance permeation through the skin. The unique ability of cannabidiol to interfere with local pain receptors allows it to address topical and internal inflammation. Active Ingredients Inactive Ingredients Attributes Directions Packaging Microbial Analysis Approved Terminology 0.35% Phytocannabinoid-Rich Hemp Oil Water/Aqua, Sweet Almond oil, Glyceryl Stearate SE, Cetyl Alcohol, Dimethicone, Isopropyl Palmitate, C12-15 Alkyl Benzoate, Sucrose Acetate Isobutyrate, Stearic Acid, Glyceryl Stearate, PEG-100 Stearate, Butyrospermum Parkii (Shea Butter) Fruit, Boswellia extract, Arnica montana extract, Aloe vera extract, Menthyl Lactate, Panthenol (ProVitamin B5), Propanediol, Phenoxyethanol, Caprylyl Glycol, Ethylhexylglycerin, Hexylene Glycol, Xanthan gum, Trisodium EDTA, Carbomer, Polysorbate 80, Polysorbate 20, Sodium hydroxide, Fragrance: Winter Mint [and] Eucalyptus Zero-THC Apply to affected areas once or twice a day. Bulk 18 Month Shelf Life Total Aerobic Count < 2,000 cfu/g Total Yeast and Mold < 200 cfu/g E. Coli = Negative Salmonella = Negative Manufactured in the USA Full Spectrum Profile This product is not intended to diagnose, treat, cure, or prevent any disease and has not been evaluated by the FDA. 25 Cosmeceuticals

27 Animal Health Dr. Robert Silver DVM, MS, CVA Chief Veterinary Officer, Folium Biosciences Dr. Robert Silver is a gifted veterinarian, researcher, and author who has been practicing medicine for over three decades. He graduated from Colorado State University s College of Veterinary Medicine in After working in Colorado Springs, Dr. Silver moved to Boulder in 1993 to establish Boulder s Natural Animal, one of the first integrative veterinary medical practices in the US. For the past 12 years, Dr. Silver has been investigating and recording the influence of cannabis on his patients; leading him to be known as the veterinary authority on treating companion animals with medicinal cannabis. Literally writing the book on how cannabis works with animals, he has documented its effects in a wide variety of conditions found in companion animals. These observations resulted in the writing of his book entitled: Medical Marijuana and Your Pet. Currently, Dr. Silver is involved in ongoing studies detailing the benefits phytocannabinoids have on animals through a multi-centered approach that involves veterinarians from around the US. Dr. Silver came to Folium Biosciences originally in 2015 where he found the high-quality hemp extracts he had been looking for on behalf of an animal nutraceutical company and was recruited to join Team Folium in February of Animal Health

28 K9 Soft Chews Zero-THC Hemp Pellets Zero-THC For Equine, Ruminants, Birds, & Pocket Pets Tinctures Zero-THC For Mammals, Birds, & Reptiles Available in 250 mg, 500 mg, 1000 mg, or 1500 mg Full Spectrum Profile 27

29 K9 Soft Chews PRODUCT DATA SHEET Product Description Active Ingredients Inactive Ingredients Recommended Dosage Attributes Packaging Microbial Analysis Contaminant Analysis Approved Terminology Our veterinarian formulated canine soft chews provide a full spectrum profile of synergistic compounds that are naturally present in our zero-thc phytocannabinoid-rich organically grown hemp oil. Each soft chew is beef flavored and easy to digest. They are specially formulated to help canines, as a supplement. 2 mg Phytocannabinoid-Rich Hemp Oil Water, dried brewer s yeast, glycerin, gum arabic, sodium alginate, beef liver powder, natural bacon flavor, flaxseed oil, microcrystalline cellulose, organic sweet potato powder, sunflower lecithin (non-gmo), citrus pectin, vitamin E, sodium propionate, calcium sulfate dehydrate, natural mixed tocopherols (natural preservative), dextrin 0.25 mg/kg 1-2 Times Daily (1 mg for every 8.8 lbs) Full Spectrum Profile Total Aerobic Count < 2,000 cfu/g Total Yeast and Mold < 200 cfu/g E. Coli = Negative Salmonella = Negative Zero-THC 10-pound bulk sealed foil bags: contain approx 1000 soft chews. Shipping carton: 2 X 10-pound bags = 20 pounds per carton (about 2,000 chews) Pallets: 84 X 10-pound bags per pallet (about 84,000 chews per pallet) Bulk Only. Heavy Metals: Not Detected (ND) Lead: ND Arsenic: ND Residual Solvents: ND Manufactured in the USA Organically Grown Hemp Veterinarian Formulated Measurements 1/2 Weight: 4.5 Grams / per piece 5/8 This product is not intended to diagnose, treat, cure, or prevent any disease and has not been evaluated by the FDA. 28 Animal Health

30 Hemp Pellets For Equine, Large and Small Ruminants, Avian & Pocket Pets PRODUCT DATA SHEET Product Description Hemp Pellets are pressed from Folium Biosciences s Hemp Meal, which contains Zero-THC and a guaranteed minimum cannabinoid content of 0.3% in dry matter. They have been assayed to contain 20% plant protein, 30% insoluble fiber and 50% complex carbohydrates. The hemp meal used to make the pellets has been sterilized, sieved, and blended for safety, efficacy, and consistency. A food-grade FDA approved mold inhibitor has been added to the pellets for additional shelf life. These pellets can be easily administered to a variety of species, including horses, donkeys, mules, goats, sheep, swine, poultry, and pet caged birds, rabbits, and pocket pets. The minimum guaranteed amount, 0.3% phytocannabinoids, provides 9-10 mg of phytocannabinoids per teaspoon and mg of phytocannabinoids per tablespoon. Active Ingredients 0.3% Phytocannabinoids Inactive Ingredients Myco Curb, Apple Ade Recommended Dosage 1 level Teaspoon = 9-10 mg phytocannabinoids 1 level Tablespoon = mg phytocannabinoids Attributes Zero-THC Packaging 25 Pound Sacks 18 Month Shelf Life Microbial Analysis Total Aerobic Count < 2,000 cfu/g Total Yeast and Mold < 200 cfu/g E. Coli = Negative Salmonella = Negative Contaminant Analysis Heavy Metals: Not Detected (ND) Lead: ND Arsenic: ND Residual Solvents: ND Approved Terminology Manufactured in the USA Organically Grown Hemp This product is not intended to diagnose, treat, cure, or prevent any disease and has not been evaluated by the FDA. Animal Health 29

31 Frequently Asked Questions with our Chief Veterinary Officer Dr. Robert J. Silver, DVM, MS Phytocannabinoids and Pets: CBD and THC Q. How does CBD work in pets? A. It works the same way it works in people, by stimulating the endocannabinoid system to create balance in the body which helps to relieve pain, reduce neurological problems, reduce anxiety, and address problems with diseases like osteoarthritis, cancer, inflammatory bowel disease, epilepsy, asthma, etc. Q. Is THC necessary for CBD to work? A. No. This was a common belief before more research was done regarding hemp s other cannabinoids. New information has shown that THC and CBD can sufficiently function without the other. Full spectrum products that are THC-free but still have several other cannabinoids present are the most beneficial as the cannabinoids are able to complement each other s individual effects. Q. Is THC safe to use in pets? A. Folium Biosciences does not recommend giving THC to animals. Every species will experience different reactions to the compound. Dogs have been found to be highly sensitive to its psychoactive properties, while cats have been shown to be less susceptible. THC in larger animals like horses can be potentially dangerous to both the animal and owner, due to THC causing excessive excitement or positive drug tests. Q. Is THC an important medicinal cannabinoid? A. THC does have clinical value when combined with CBD for severe pain and aggressive types of cancer. Other than those two applications, the other major and minor cannabinoids and terpenes found in full spectrum hemp extracts are more than adequate to address most clinical conditions responsive to cannabinoids. 30

32 Phytocannabinoids and Animals: Dosing and Drug Testing Q. What is the recommended dosage for pets? A. We always suggest starting with a low dosage and seeing how it affects the animal before moving up. For the most common ailments, such as anxiety or mild pain, the lowest dose twice a day works very well. Even for more severe problems, the positive reaction to CBD can be profound enough at this low dosage to benefit the quality of life entirely. Every individual is unique and will process cannabinoids differently, meaning that there is no one-size-fits-all dose for all animals. The best way to make sure that the animal is receiving an adequate amount of CBD is to start low and monitor behavior for 5-10 days before increasing intake. RECOMMENDED DOSAGES FOR PETS Dosage per pound per 10 pounds low 0.05 mg 0.5 mg mid 0.10 mg 1.0 mg high 0.25 mg 2.5 mg Q. How was the recommended dose calculated? A. Several scientific studies were analyzed and compared with first-hand evidence to create the recommended dose. Study groups of neurology and oncology veterinary specialists were given Folium s Phytocannabinoid-rich (PCR) tinctures to administer to their patients and examine the outcomes. Through their results and overwhelming anecdotal evidence collected over the course of two years from other vets and pet owners, this was determined to be the most advantageous dose to begin with. Q. What is the recommended dosage for horses? A. Folium Biosciences had several equine veterinarians test CBD dosages on numerous horses to find the ideal amount needed for a given condition. Horses are very efficient at absorbing phytocannabinoids. For example, anxiety, a common occurrence when eventing or loading onto a trailer, was greatly reduced with the use of 25 mg once or twice a day. Mild lameness or pain was also remedied by that same dosage. For more serious conditions like laminitis, marked lameness, metabolic syndrome, or Cushing s disease, 50 mg twice daily made a notable improvement. Q. Will drug testing be a problem for equestrian events? A. Currently, in the US, horses are only being tested for THC, not CBD. Rules regarding CBD in these cases are subject to change, and we will be continually monitoring any development in this area. While the federal law on hemp allows small amounts of THC to be present, Folium Biosciences prides itself on creating zero-thc hemp products. Animals will not show a positive THC result on drug tests when using Folium s PCR hemp products, which very few hemp companies can promise. 31 Animal Health

33 Bottle & Container Specifications Pipette 1 ml of Liquid oz Amber / Cobalt Glass Dropper Bottle Max Safe Label Dimensions: W: 3.75 x H: 1.6 RECYCLABLE BOTTLE CAPACITY 30cc / 1oz / 30ml NECK FINISH OVERFLOW CAPACITY 36.2cc / 1.2oz / 35.5ml HEIGHT(W/Dropper) 4in / 101.6mm DIAMETER 1.25in / 31.75mm RECOMMENDED APPLICATIONS: Tinctures Vape & E-Juice Heat Resistant up to 400 F Impact Resistance Rigidity Scratch Resistance / / oz Straight Sided Glass Jar 2 7 Max Safe Label Dimensions: W: 6 x H: 1 RECYCLABLE BOTTLE CAPACITY cc / 2oz NECK FINISH OVERFLOW CAPACITY 76.9cc / 2.6oz HEIGHT 1.922in / 48.82mm DIAMETER 2.153in / 54.69mm RECOMMENDED APPLICATIONS: Balm Salve Heat Resistant up to 930 F Impact Resistance Rigidity Scratch Resistance oz Straight Sided Glass Jar RECYCLABLE Max Safe Label Dimensions: W: 5 x H:.75 BOTTLE CAPACITY 30cc / 1oz NECK FINISH OVERFLOW CAPACITY 38.45cc / 1.3oz HEIGHT 1.73in / 43.94mm DIAMETER 1.73in / 43.94mm RECOMMENDED APPLICATIONS: Balm Salve Heat Resistant up to 930 F Impact Resistance Rigidity Scratch Resistance oz Cobalt / Amber PET Packer Bottle RECYCLABLE Max Safe Label Dimensions: W: 5 x H: 2 BOTTLE CAPACITY 75cc / 2.5oz NECK FINISH OVERFLOW CAPACITY 93cc / 3.14oz HEIGHT 3.25in / 82.55mm DIAMETER 1.66in / 42.06mm RECOMMENDED APPLICATIONS: Softgels Heat Resistant up to 120 F Impact Resistance Rigidity Scratch Resistance

34 FBPro All information in this document is property of Folium Biosciences and may not be reproduced or distributed without express written permission. 33

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